Eukaryotic Ribosome Scanning

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<a href="https://pubmed.ncbi.nlm.nih.gov/38266075" target='_blank' title="Yeast eIF2A has a minimal role in translation initiation and uORF-mediated translational control in vivo.">Yeast eIF2A has a minimal role in translation initiation and uORF-mediated translational control in vivo.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/39091764" target='_blank' title="Leaky ribosomal scanning enables tunable translation of bicistronic ORFs in green algae.">Leaky ribosomal scanning enables tunable translation of bicistronic ORFs in green algae.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38863530" target='_blank' title="Critical -parameters influence STructure assisted RNA translation (START) initiation on non-AUG codons in eukaryotes.">Critical -parameters influence STructure assisted RNA translation (START) initiation on non-AUG codons in eukaryotes.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38232291" target='_blank' title="A second-generation eIF4A RNA helicase inhibitor exploits translational reprogramming as a vulnerability in triple-negative breast cancer.">A second-generation eIF4A RNA helicase inhibitor exploits translational reprogramming as a vulnerability in triple-negative breast cancer.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/39005336" target='_blank' title="Deciphering the regulatory landscape of natural yeast Transcript Leaders.">Deciphering the regulatory landscape of natural yeast Transcript Leaders.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/39289545" target='_blank' title="Structural basis for translational control by the human 48S initiation complex.">Structural basis for translational control by the human 48S initiation complex.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38138978" target='_blank' title="The Roles of eIF4G2 in Leaky Scanning and Reinitiation on the Human Dual-Coding POLG mRNA.">The Roles of eIF4G2 in Leaky Scanning and Reinitiation on the Human Dual-Coding POLG mRNA.</a> </div> <p><strong>Issue Release:</strong> 2023</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38052923" target='_blank' title="The molecular basis of translation initiation and its regulation in eukaryotes.">The molecular basis of translation initiation and its regulation in eukaryotes.</a> </div> <p><strong>Issue Release:</strong> 2023</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/36882295" target='_blank' title="Exploring the Targeting Spectrum of Rocaglates Among eIF4A Homologs.">Exploring the Targeting Spectrum of Rocaglates Among eIF4A Homologs.</a> </div> <p><strong>Issue Release:</strong> 2023</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/37986989" target='_blank' title="Yeast eIF2A has a minimal role in translation initiation and uORF-mediated translational control in vivo.">Yeast eIF2A has a minimal role in translation initiation and uORF-mediated translational control in vivo.</a> </div> <p><strong>Issue Release:</strong> 2023</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/36869665" target='_blank' title="PRRC2 proteins impact translation initiation by promoting leaky scanning.">PRRC2 proteins impact translation initiation by promoting leaky scanning.</a> </div> <p><strong>Issue Release:</strong> 2023</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/35554027" target='_blank' title="DAP5 Binding to the FGF-9 mRNA 5\' UTR is Structurally-Dependent.">DAP5 Binding to the FGF-9 mRNA 5\' UTR is Structurally-Dependent.</a> </div> <p><strong>Issue Release:</strong> 2022</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/36517212" target='_blank' title="Specific Mechanisms of Translation Initiation in Higher Eukaryotes: The eIF4G2 Story.">Specific Mechanisms of Translation Initiation in Higher Eukaryotes: The eIF4G2 Story.</a> </div> <p><strong>Issue Release:</strong> 2022</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/36510274" target='_blank' title="Distance-dependent inhibition of translation initiation by downstream out-of-frame AUGs is consistent with a Brownian ratchet process of ribosome scanning.">Distance-dependent inhibition of translation initiation by downstream out-of-frame AUGs is consistent with a Brownian ratchet process of ribosome scanning.</a> </div> <p><strong>Issue Release:</strong> 2022</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/35031321" target='_blank' title="Stepwise assembly of the eukaryotic translation initiation factor 2 complex.">Stepwise assembly of the eukaryotic translation initiation factor 2 complex.</a> </div> <p><strong>Issue Release:</strong> 2022</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/34900714" target='_blank' title="Zotatifin, an eIF4A-Selective Inhibitor, Blocks Tumor Growth in Receptor Tyrosine Kinase Driven Tumors.">Zotatifin, an eIF4A-Selective Inhibitor, Blocks Tumor Growth in Receptor Tyrosine Kinase Driven Tumors.</a> </div> <p><strong>Issue Release:</strong> 2021</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/34887587" target='_blank' title="Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.">Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.</a> </div> <p><strong>Issue Release:</strong> 2021</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/34782646" target='_blank' title="Bi-directional ribosome scanning controls the stringency of start codon selection.">Bi-directional ribosome scanning controls the stringency of start codon selection.</a> </div> <p><strong>Issue Release:</strong> 2021</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/34353608" target='_blank' title="1-Aminomethyl SAR in a novel series of flavagline-inspired eIF4A inhibitors: Effects of amine substitution on cell potency and in vitro PK properties.">1-Aminomethyl SAR in a novel series of flavagline-inspired eIF4A inhibitors: Effects of amine substitution on cell potency and in vitro PK properties.</a> </div> <p><strong>Issue Release:</strong> 2021</p> </div> </div> </div> <div id="way2buy_left_banner_1" class="rightads"></div> </div> <div class="col-md-4 mt-50"> <style> 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Eukaryotic Ribosome Scanning - Cell Biology