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OXLUMO® (lumasiran) | Official Patient Website
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</li> <li class="last"> <a href="https://www.oxlumohcp.com/" class="hcp_site">HEALTHCARE PROFESSIONAL SITE</a> </li> </ul> </nav> </div> <div class="region region-header-third"> <div id="block-connectbutton" class="block block-block-content block-block-contentac762462-41f1-4379-a040-8cb090514b2c"> <div class="field--item"><p><a class="btn js-close-isi js-close-mobile" href="/patient-education-liaisons">CONNECT WITH AN ALNYLAM EDUCATOR</a></p> </div> </div> </div> </div> </div> <div class="header_bottom"> <div class="wrapper"> </div> </div> </header> <main role="main" class="main-container js-quickedit-main-content"> <div class="region region-content-top"> <div data-drupal-messages-fallback class="hidden"></div> </div> <section> <a id="main-content"></a> <div class="region region-content"> <div id="block-oxlumo-content" class="block block-system block-system-main-block"> <article data-history-node-id="1" role="article" about="/home" typeof="schema:WebPage" class="node node--type-page node--view-mode-full"> <span property="schema:name" content="Homepage" class="rdf-meta hidden"></span> <div class="node__content"> <div class="field field--name-field-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <section class="home-hero" > <div class="wrapper"> <div class="field field--name-field-sub-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--full-html-content paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-content field--type-text-long field--label-hidden field--items"> <div class="field--item"><article class="media media--type-image media--view-mode-default"><div class="field--label sr-only">Image</div> <div class="field--item"> <img src="/sites/default/files/2022-01/logo-large.png" width="363" height="97" alt="" loading="lazy" typeof="foaf:Image" /></div> </article><h1 style="line-height: 1.2;">The first approved PH1 prescription medication for people of all ages and stages of kidney function.<span class="hide_desktop"><sup>†</sup></span><span class="hide_mobile">*</span></h1> <h3 style="color: inherit;">OXLUMO® (lumasiran) is a prescription medicine for the treatment of primary hyperoxaluria type 1 (PH1) to lower oxalate in urine and blood in children and adults.</h3> <p class="note dagger hide_desktop">OXLUMO was studied in infants, children, and adults with different stages of kidney disease from near normal (not on hemodialysis) up to advanced kidney disease, including patients on hemodialysis.</p> <p class="note asterisk hide_mobile">OXLUMO was studied in infants, children, and adults with different stages of kidney disease from near normal (not on hemodialysis) up to advanced kidney disease, including patients on hemodialysis.</p> <p><a class="btn arrow" href="/about-oxlumo">Tell Me About OXLUMO®</a> <a class="btn btn-secondary arrow" href="/what-is-primary-hyperoxaluria-type-1">Learn More About PH1</a></p> <div class="caption"> <div class="name"><strong>Natalie</strong><br /><strong><em>Person with PH1<sup class="hide_mobile">†</sup><span class="hide_desktop">*</span></em></strong></div> <strong><sup class="hide_mobile">†</sup><span class="hide_desktop">*</span>Alnylam is proud to feature real patients in our advertising. Patients may or may not be on an Alnylam therapy.</strong></div> </div> </div> </div> </div> </div> </div> </section> </div> <div class="field--item"> <section class="columns image-text" > <div class="wrapper"> <div class="field field--name-field-sub-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--full-html-content paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-content field--type-text-long field--label-hidden field--items"> <div class="field--item"><article class="asdf align-center media media--type-image media--view-mode-default"><div class="field--label sr-only">Image</div> <div class="field--item"> <img src="/sites/default/files/2022-01/family-icon-large.svg" alt="" loading="lazy" typeof="foaf:Image" /></div> </article></div> <div class="field--item"><h2>OXLUMO works by reducing oxalate production in infants, children, and adults</h2> <p>OXLUMO is a prescription medicine for the treatment of primary hyperoxaluria type 1 (PH1) to lower oxalate in urine and blood in children and adults.</p> <p class="mobile_center"><a class="btn arrow" href="/about-oxlumo">Show Me the Results</a></p> </div> </div> </div> </div> </div> </div> </section> </div> <div class="field--item"> <section class="columns text-image" > <div class="wrapper"> <div class="field field--name-field-sub-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--full-html-content paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-content field--type-text-long field--label-hidden field--items"> <div class="field--item"><h2>What to expect from treatment with OXLUMO</h2> <p>Learn about how OXLUMO is given.</p> <p class="mobile_center"><a class="btn arrow" href="/starting-oxlumo">Take Me There</a></p> <p class="mobile_center"><a class="btn btn-secondary arrow " href="/patient-support">Get Started With OXLUMO</a></p> </div> <div class="field--item"><article class="align-center media media--type-image media--view-mode-default"><div class="field--label sr-only">Image</div> <div class="field--item"> <img src="/sites/default/files/2022-01/calendar-icon-large.svg" alt="" loading="lazy" typeof="foaf:Image" /></div> </article></div> </div> </div> </div> </div> </div> </section> </div> <div class="field--item"> <section class="callout educator" > <div class="wrapper"> <div class="field field--name-field-sub-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--full-html-content paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-content field--type-text-long field--label-hidden field--items"> <div class="field--item"><article class="align-center media media--type-image media--view-mode-default"><div class="field--label sr-only">Image</div> <div class="field--item"> <img src="/sites/default/files/2022-01/educator-icon.svg" alt="" loading="lazy" typeof="foaf:Image" /></div> </article><h2 class="text-align-center">CONNECT WITH AN ALNYLAM EDUCATOR</h2> <p class="text-align-center">Learn about primary hyperoxaluria type 1 (PH1) and treatment with OXLUMO® from one of our trained Alnylam Patient Education Liaisons (PELs).</p> <p class="note text-align-center">PELs are employees of Alnylam Pharmaceuticals. They are not acting as healthcare providers and are not part of your healthcare team.</p> <p class="text-align-center"><a class="btn" href="/patient-education-liaisons">Let’s Connect</a></p> </div> </div> </div> </div> </div> </div> </section> </div> <div class="field--item"> <section class="columns support pb-32" > <div class="wrapper"> <div class="field field--name-field-sub-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--full-html-content paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-content field--type-text-long field--label-hidden field--items"> <div class="field--item"><article class="align-center media media--type-image media--view-mode-default"><div class="field--label sr-only">Image</div> <div class="field--item"> <img src="/sites/default/files/2022-01/dialog-icon-large.svg" alt="" loading="lazy" typeof="foaf:Image" /></div> </article><h2>We’re here to help you access therapy</h2> <p>Find support services that can help you and your family during treatment with OXLUMO.</p> <p class="mobile_center"><a class="btn btn-secondary" href="/patient-support">Let’s Go</a></p> </div> <div class="field--item"><article class="align-center media media--type-image media--view-mode-default"><div class="field--label sr-only">Image</div> <div class="field--item"> <img src="/sites/default/files/2020-10/sign-up-icon.svg" alt="" loading="lazy" typeof="foaf:Image" /></div> </article><h2>Sign up for updates</h2> <p>Learn more by signing up to receive important content.</p> <p class="mobile_center"><a class="btn btn-secondary" href="/sign-up-for-updates">Sign Me Up</a></p> </div> </div> </div> </div> </div> </div> </section> </div> </div> <div property="schema:text" class="field--item"></div> </div> </article> </div> </div> </section> <div class="region region-content-bottom"> <div id="block-importantsafetyinformation" class="isi block block-block-content block-block-content63d76fc1-b7f0-475f-917b-98825b6fba84"> <span class="close-isi"></span> <span class="open-isi"></span> <div class="field--item"><p class="h3">IMPORTANT SAFETY INFORMATION</p> <p>The most common side effect of OXLUMO® (lumasiran) is injection site reaction (redness, swelling, pain, bruising, itching, and discoloration at the site of injection). These are not all the possible side effects of OXLUMO. Talk to your doctor about side effects that you experience. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit <strong><a class="js-open-inter" href="https://www.fda.gov/medwatch" target="_blank">www.fda.gov/medwatch</a></strong>, or call <strong><a href="tel:1-800-FDA-1088">1‑800‑FDA‑1088</a></strong>.</p> <p>OXLUMO has not been studied in pregnant or breastfeeding women. Talk to your doctor about the risk of taking OXLUMO if you are pregnant, plan to become pregnant, are breastfeeding, or plan to breastfeed.</p> <p class="h3">WHAT IS OXLUMO?</p> <p>OXLUMO is a prescription medicine for the treatment of primary hyperoxaluria type 1 (PH1) to lower oxalate in urine and blood in children and adults. </p> <p><strong style="color: inherit;">For additional information about OXLUMO, please see full <a href="https://www.alnylam.com/oxlumo-us-prescribing-information" target="_blank">Prescribing Information</a>.</strong></p> </div> </div><div id="block-corporateinterstitial" class="block block-block-content block-block-content6e2edfba-b157-4b45-b715-dc959aab885e"> <div class="field--item"><div class="popup" id="corp_inter"> <div class="wrapper"><a class="close js-close-popup" href="#">×</a> <p class="h3">You are now leaving OXLUMO.com</p> <p>You are now being directed to another Alnylam website.</p> <p><a class="btn link js-close-popup" href="#">Visit Site</a> <a class="btn btn-secondary js-close-popup" href="#">Cancel</a></p> </div> </div> <div class="popup" id="inter"> <div class="wrapper"><a class="close js-close-popup" href="#">×</a> <p class="h3">You are now leaving OXLUMO.com</p> <p>Links to all outside sites are provided as a reference for our visitors. 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