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Patient Support | OXLUMO® (lumasiran)
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Patients may or may not be on an Alnylam therapy.</p> <h1 class="text-align-center">Alnylam Assist® is experienced in providing support services to patients on OXLUMO® (lumasiran)</h1> <p class="text-align-center"><strong>When you and your doctor choose to begin treatment with OXLUMO and to enroll in Alnylam Assist®, the next step is to complete the Start Form together. </strong></p> <p class="text-align-center">Your doctor will submit the form to Alnylam Assist®. Upon receipt of the <a href="https://www.alnylamassist.com/oxlumo/get-started">Start Form</a>, an Alnylam Case Manager will reach out to you and your doctor within 2 business days.</p> </div> </div> </div> </div> </div> </div> </section> </div> <div class="field--item"> <section class="pb-0" > <div class="wrapper"> <div class="field field--name-field-sub-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--full-html-content paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-content field--type-text-long field--label-hidden field--items"> <div class="field--item"><h2 class="text-align-center">Experienced Team Members</h2> <h3 class="text-align-center darkgreen">An Alnylam Case Manager</h3> <p class="text-align-center">When you and your healthcare provider choose to begin treatment with OXLUMO, you will be partnered with an Alnylam Case Manager. Case Managers are trained professionals whose expertise is in helping patients get started on treatment and providing product support.</p> <ul class="flex-list"> <li>Helping you get started on treatment</li> <li>Understanding your insurance benefits</li> <li>Providing you with product support throughout your treatment</li> <li>Determining your eligibility for financial assistance*</li> </ul> <h3 class="mt-48 text-align-center darkgreen">An Alnylam Patient Education Liaison (PEL)</h3> </div> </div> </div> </div> </div> </div> </section> </div> <div class="field--item"> <section class="columns image-text pt-32" > <div class="wrapper"> <div class="field field--name-field-sub-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--full-html-content paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-content field--type-text-long field--label-hidden field--items"> <div class="field--item"><article class="align-center media media--type-image media--view-mode-default"><div class="field--label sr-only">Image</div> <div class="field--item"> <img src="/sites/default/files/2023-03/patient-education-liason-hex-icon.svg" alt="" loading="lazy" typeof="foaf:Image" /></div> </article></div> <div class="field--item"><h3>A PEL can help</h3> <p>The purpose of the PELs program is to provide education for patients, their families, and caregivers. PELs have a background in nursing and experience in educating patients and families about PH1 and providing information about treatment with OXLUMO. </p> <p>They can help:</p> <ul> <li>Support you with understanding PH1</li> <li>Explain how OXLUMO works</li> <li>Answer questions about treatment with OXLUMO</li> <li>Connect you with additional resources</li> </ul> <p>PELs are employees of Alnylam Pharmaceuticals. They are not acting as healthcare providers and are not part of your healthcare team.</p> <p>PELs do not provide medical care or advice. All diagnosis and treatment decisions should be made by you and your doctor.</p> </div> </div> </div> </div> </div> </div> </section> </div> <div class="field--item"> <section class="thinner pt-48 pb-32" > <div class="wrapper"> <div class="field field--name-field-sub-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--full-html-content paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-content field--type-text-long field--label-hidden field--items"> <div class="field--item"><p class="text-align-center"><strong>For more information about Alnylam Assist® or to access downloadable materials:</strong></p> <div class="flex-list"> <div> <p class="text-align-center"><a class="js-open-corp-inter" href="https://www.alnylamassist.com/oxlumo/your-team" target="_blank"><img alt="Alnylam Assist" src="/sites/default/files/2020-08/alnylam-assist-logo.svg" typeof="foaf:Image" /></a></p> </div> <div> <p class="mobile_center"><strong><a class="js-open-corp-inter" href="https://alnylamassist.com/oxlumo" id="home-nurse" target="_blank">Visit: AlnylamAssist.com</a></strong></p> <p class="mobile_center"><a class="mobile_call nursing_call" href="tel:1-833-256-2748"><span class="call_box"><span class="call_box_inner"><span class="phone"><strong>Call: <span class="number">1-833-256-2748</span></strong></span> <span class="hours">Monday-Friday, 8<sub> AM</sub>-6<sub> PM</sub></span></span></span></a></p> </div> </div> <h2 class="text-align-center">Alnylam Assist® is here to help you access treatment</h2> <p class="text-align-center tiny_left">Alnylam offers a support program for patients receiving OXLUMO. Support services include:<br /> <span class="hide_desktop"> </span></p> </div> </div> </div> </div> </div> </div> </section> </div> <div class="field--item"> <section class="shorter pt-0 pb-0" > <div class="wrapper"> <div class="field field--name-field-sub-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--full-html-content paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-content field--type-text-long field--label-hidden field--items"> <div class="field--item"><p><span><strong>Financial Assistance</strong></span><br /> Alnylam offers financial assistance programs for eligible patients. After being prescribed OXLUMO, you can talk to an Alnylam Case Manager to learn if you may be eligible.* Below are examples of two Alnylam Financial Assistance programs.</p> <ul> <li>I have insurance but have concerns about paying for OXLUMO <ul> <li>Our Commercial Copay Program covers certain out-of-pocket costs for eligible patients with commercial insurance<sup>†</sup></li> </ul> </li> </ul> <ul> <li>I’m uninsured, or I have insurance but do not have coverage for OXLUMO <ul> <li>Our Patient Assistance Program may be able to provide you with one of Alnylam's products at no cost if you’re eligible</li> </ul> </li> </ul> <p><br class="hide_desktop" /> <span> </span></p> </div> </div> </div> </div> </div> </div> </section> </div> <div class="field--item"> <section class="tiny_left pt-0" > <div class="wrapper"> <div class="field field--name-field-sub-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--full-html-content paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-content field--type-text-long field--label-hidden field--items"> <div class="field--item"><p class="note asterisk">Patients must meet specified eligibility criteria to qualify for assistance. Alnylam reserves the right to make eligibility determinations and to modify or discontinue any program at any time.</p> <p class="note dagger">Patients with Medicare, Medicaid, or other government-sponsored insurance are not eligible for the Alnylam Assist® Commercial Copay Program. Out-of-pocket costs for the administration of Alnylam products will not be covered for patients residing where it is prohibited by law or where otherwise restricted.</p> <p style="height: 1px;"> </p> <p style="height: 1px;"> </p> <p class="text-align-center mobile_center"><a class="btn outicon js-open-corp-inter" href="https://alnylamassist.com/oxlumo" id="home-nurse" target="_blank">Visit AlnylamAssist.com</a></p> </div> </div> </div> </div> </div> </div> </section> </div> <div class="field--item"> <section class="columns image-text green_image" > <div class="wrapper"> <div class="field field--name-field-sub-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--full-html-content paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-content field--type-text-long field--label-hidden field--items"> <div class="field--item"><article class="align-center media media--type-image media--view-mode-default"><div class="field--label sr-only">Image</div> <div class="field--item"> <img src="/sites/default/files/2020-10/in-home-nursing-icon.svg" alt="" loading="lazy" typeof="foaf:Image" /></div> </article></div> <div class="field--item"><h3>In-home nursing support services</h3> <p>Depending on your doctor's recommendations and if your insurance coverage allows, you may be able to have a healthcare professional administer OXLUMO in your home.*</p> <p><strong>Reach out to Alnylam Assist® with questions. </strong></p> <p class="mobile_center"><a class="mobile_call nursing_call" href="tel:1-833-256-2748"><span class="call_box"><span class="call_box_inner"><span class="phone"><strong>Call: <span class="number">1-833-256-2748</span></strong></span> <span class="hours">Monday-Friday, 8<sub> AM</sub>-6<sub> PM</sub></span></span></span></a></p> <p class="note asterisk" style="margin-top: 2em;">Once you and your doctor have decided to start treatment with OXLUMO, you can call Alnylam Assist® to find out if you may be eligible for at‑home administration based on your insurance coverage.</p> </div> </div> </div> </div> </div> </div> </section> </div> <div class="field--item"> <section class="newSection hide_desktop hide_mobile" > <div class="wrapper"> <div class="field field--name-field-sub-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--full-html-content paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-content field--type-text-long field--label-hidden field--items"> <div class="field--item"><h2 class="text-align-center">Patient & Caregiver Stories</h2> <div class="ox-flex"> <div class="ox-row"> <div class="ox-col-1"> <article class="media media--type-image media--view-mode-default"><div class="field--label sr-only">Image</div> <div class="field--item"> <img src="/sites/default/files/2024-07/Group%2031.png" width="270" height="270" alt="Kelly" loading="lazy" typeof="foaf:Image" /></div> </article></div> <div class="ox-col-2"> <div class="name">Meet Kelly</div> <div class="userType">Patient</div> <blockquote class="content">“When I go and see my doctor now, I’m excited...my doctor is just thrilled to see my levels—OXLUMO exceeded my expectations.”</blockquote> <div class="f-bold">Learn more about Kelly's journey.</div> <div class="action"><a class="btn download">Download</a></div> </div> </div> <div class="ox-row"> <div class="ox-col-1"> <article class="media media--type-image media--view-mode-default"><div class="field--label sr-only">Image</div> <div class="field--item"> <img src="/sites/default/files/2024-07/Rectangle%207.png" width="90" height="90" alt="Amy" loading="lazy" typeof="foaf:Image" /></div> </article></div> <div class="ox-col-2"> <div class="name">Meet Amy</div> <div class="userType">Caregiver</div> <blockquote class="content">"Owen’s and my experience with OXLUMO has connected us to the community through the hope for better outcomes than there have been previously."</blockquote> <div class="f-bold">Learn more about Amy’s journey.</div> <div class="action"><a class="btn download">Download</a></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </section> </div> <div class="field--item"> <section class="faq" > <div class="wrapper"> <div class="field field--name-field-sub-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--full-html-content paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-content field--type-text-long field--label-hidden field--items"> <div class="field--item"><h2>Frequently asked questions about OXLUMO</h2> <dl> <dt>Who can take OXLUMO?</dt> <dd> <p>OXLUMO is a prescription medicine for the treatment of primary hyperoxaluria type 1 (PH1) to lower oxalate in urine and blood in children and adults. You and your doctor will determine if OXLUMO is right for you.</p> </dd> <dt>What is OXLUMO and how does it work?</dt> <dd> <p>OXLUMO is a prescription medicine for the treatment of PH1 to lower oxalate in urine and blood in children and adults.</p> <ul> <li>OXLUMO targets the GO enzyme—a liver enzyme involved in making oxalate</li> <li>OXLUMO reduces levels of the GO enzyme so that less oxalate is made and sent to the kidneys</li> </ul> </dd> <dt>What is the most common side effect?</dt> <dd> <p>The most common side effect is injection site reaction (redness, swelling, pain, bruising, itching, and discoloration at the site of injection). This is not the only possible side effect of OXLUMO. Talk to your doctor about side effects that you experience. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit <strong> <a class="js-open-inter" href="https://www.fda.gov/medwatch" target="_blank">www.fda.gov/medwatch</a> </strong>, or call <strong> <a href="tel:1-800-FDA-1088">1‑800‑FDA‑1088</a> </strong>.</p> </dd> <dt>How is OXLUMO given?</dt> <dd> <p>OXLUMO is an injection administered by a healthcare provider. OXLUMO is injected under the skin. Injection sites can include the area under the skin on the abdomen, thighs, or upper arms.</p> <p>Dosing of OXLUMO is based on the patient’s weight. Dosing happens in 2 phases:</p> <ul> <li> <p>The first 4 doses are taken a month apart. The first 3 are starting doses to <strong>help bring oxalate levels down</strong>. The 4th is the first ongoing dose and is given one month after the last starting dose.</p> </li> <li> <p>Ongoing dosing is quarterly (every 3 months) or monthly, <strong>depending on the patient’s weight</strong>.</p> <ul> <li> <p>For children under 10 kg (22 lb), 1 DOSE EVERY MONTH</p> </li> <li> <p>For patients weighing 10 kg (22 lb) or more, 1 DOSE EVERY 3 MONTHS</p> </li> </ul> </li> <li> <p>For patients on hemodialysis, OXLUMO will be administered after hemodialysis if administered on dialysis days.</p> </li> </ul> <p>The most common side effect of OXLUMO is injection site reaction (redness, swelling, pain, bruising, itching, discoloration at the site of injection).</p> </dd> <dt>How can Alnylam Assist® help me?</dt> <dd> <p>Alnylam Assist® is here to help patients who are prescribed OXLUMO access treatment and learn more.</p> <p>After you and your doctor decide to begin OXLUMO and enroll in Alnylam Assist®, we can provide support in 3 key areas</p> <ul> <li>Understanding Benefits</li> <li>Eligibility for Financial Assistance*</li> <li>Disease and Product Education</li> </ul> <p>A trained Alnylam Patient Education Liaison (PEL)<sup>†</sup> is available to help you learn more about PH1 and OXLUMO. Visit the Alnylam Assist® website to learn more.</p> <p class="note asterisk">Individuals must meet specified criteria to qualify for assistance. Alnylam reserves the right to make eligibility determinations and to modify or discontinue the program at any time.</p> <p class="note dagger">PELs are employees of Alnylam Pharmaceuticals. They are not acting as healthcare providers and are not part of your healthcare team.</p> <p class="mobile_center"><a class="btn btn-secondary outicon js-open-corp-inter" href="https://alnylamassist.com/oxlumo" target="_blank">Take Me to Alnylam Assist®</a></p> </dd> </dl> </div> </div> </div> </div> </div> </div> </section> </div> <div class="field--item"> <section class="callout white sub_heading shorter pb-0" > <div class="wrapper"> <div class="field field--name-field-sub-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--full-html-content paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-content field--type-text-long field--label-hidden field--items"> <div class="field--item"><h2 class="text-align-center">Other resources and organizations</h2> <p class="text-align-center">You and your family may find the following independent sites and organizations helpful.</p> </div> </div> </div> </div> </div> </div> </section> </div> <div class="field--item"> <section class="groups shorter" > <div class="wrapper"> <div class="field field--name-field-sub-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--full-html-content paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-content field--type-text-long field--label-hidden field--items"> <div class="field--item"><article class="align-center media media--type-image media--view-mode-default"><div class="field--label sr-only">Image</div> <div class="field--item"> <img src="/sites/default/files/2020-10/oxalosis-and-hyperoxaluria-foundation-logo.png" width="320" height="120" alt="Oxalosis and Hyperoxaluria Foundation Logo" loading="lazy" typeof="foaf:Image" /></div> </article><p class="text-align-center"><a class="btn btn-secondary js-open-inter" href="https://www.ohf.org/" target="_blank">Visit Site</a></p> </div> <div class="field--item"><article class="align-center media media--type-image media--view-mode-default"><div class="field--label sr-only">Image</div> <div class="field--item"> <img src="/sites/default/files/2020-10/american-kidney-fund-logo.png" width="320" height="120" alt="American Kidney Fund Logo" loading="lazy" typeof="foaf:Image" /></div> </article><p class="text-align-center"><a class="btn btn-secondary js-open-inter" href="https://www.kidneyfund.org/" target="_blank">Visit Site</a></p> </div> <div class="field--item"><article class="align-center media media--type-image media--view-mode-default"><div class="field--label sr-only">Image</div> <div class="field--item"> <img src="/sites/default/files/2020-12/national-kidney-foundation-logo.png" width="254" height="116" alt="National Kidney Foundation Logo" loading="lazy" typeof="foaf:Image" /></div> </article><p class="text-align-center"><a class="btn btn-secondary js-open-inter" href="https://www.kidney.org/" target="_blank">Visit Site</a></p> </div> </div> </div> </div> </div> </div> </section> </div> <div class="field--item"> <section class="note shorter pt-32" > <div class="wrapper"> <div class="field field--name-field-sub-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--full-html-content paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-content field--type-text-long field--label-hidden field--items"> <div class="field--item"><p>We hope you find the resources mentioned here helpful. Alnylam Pharmaceuticals is not affiliated with these organizations. By listing these resources, Alnylam Pharmaceuticals is not endorsing any particular service or group, and we are not responsible for the content of these sites or services. They are provided for informational purposes and should not replace your doctor’s medical advice.</p> </div> </div> </div> </div> </div> </div> </section> </div> <div class="field--item"> <section class="callout educator" > <div class="wrapper"> <div class="field field--name-field-sub-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--full-html-content paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-content field--type-text-long field--label-hidden field--items"> <div class="field--item"><article class="align-center media media--type-image media--view-mode-default"><div class="field--label sr-only">Image</div> <div class="field--item"> <img src="/sites/default/files/2022-01/educator-icon.svg" alt="" loading="lazy" typeof="foaf:Image" /></div> </article><h2 class="text-align-center">CONNECT WITH AN ALNYLAM EDUCATOR</h2> <p class="text-align-center">Learn about primary hyperoxaluria type 1 (PH1) and treatment with OXLUMO® from one of our trained Alnylam Patient Education Liaisons (PELs).</p> <p class="note text-align-center">PELs are employees of Alnylam Pharmaceuticals. They are not acting as healthcare providers and are not part of your healthcare team.</p> <p class="text-align-center"><a class="btn" href="/patient-education-liaisons">Let’s Connect</a></p> </div> </div> </div> </div> </div> </div> </section> </div> <div class="field--item"> <section class="callout green" > <div class="wrapper"> <div class="field field--name-field-sub-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--full-html-content paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-content field--type-text-long field--label-hidden field--items"> <div class="field--item"><a href="/patient-education-liaisons"> <span class="inner"> <span class="left_text"> <p><em>NEXT:</em></p> <p class="hide_mobile">CONNECT WITH AN ALNYLAM PATIENT EDUCATION LIAISON (PEL) TODAY</p> </span> <span class="hide_mobile align-center media"> <img src="/sites/default/files/2020-07/slash.svg" alt="" typeof="foaf:Image"> </span> <span class="right_text">CONNECT WITH AN<br> <span class="arrow">ALNYLAM EDUCATOR</span> </span> </span> </a></div> </div> </div> </div> </div> </div> </section> </div> </div> <div property="schema:text" class="field--item"></div> </div> </article> </div> </div> </section> <div class="region region-content-bottom"> <div id="block-importantsafetyinformation" class="isi block block-block-content block-block-content63d76fc1-b7f0-475f-917b-98825b6fba84"> <span class="close-isi"></span> <span class="open-isi"></span> <div class="field--item"><p class="h3">IMPORTANT SAFETY INFORMATION</p> <p>The most common side effect of OXLUMO® (lumasiran) is injection site reaction (redness, swelling, pain, bruising, itching, and discoloration at the site of injection). These are not all the possible side effects of OXLUMO. Talk to your doctor about side effects that you experience. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit <strong><a class="js-open-inter" href="https://www.fda.gov/medwatch" target="_blank">www.fda.gov/medwatch</a></strong>, or call <strong><a href="tel:1-800-FDA-1088">1‑800‑FDA‑1088</a></strong>.</p> <p>OXLUMO has not been studied in pregnant or breastfeeding women. Talk to your doctor about the risk of taking OXLUMO if you are pregnant, plan to become pregnant, are breastfeeding, or plan to breastfeed.</p> <p class="h3">WHAT IS OXLUMO?</p> <p>OXLUMO is a prescription medicine for the treatment of primary hyperoxaluria type 1 (PH1) to lower oxalate in urine and blood in children and adults. </p> <p><strong style="color: inherit;">For additional information about OXLUMO, please see full <a href="https://www.alnylam.com/oxlumo-us-prescribing-information" target="_blank">Prescribing Information</a>.</strong></p> </div> </div><div id="block-corporateinterstitial" class="block block-block-content block-block-content6e2edfba-b157-4b45-b715-dc959aab885e"> <div class="field--item"><div class="popup" id="corp_inter"> <div class="wrapper"><a class="close js-close-popup" href="#">×</a> <p class="h3">You are now leaving OXLUMO.com</p> <p>You are now being directed to another Alnylam website.</p> <p><a class="btn link js-close-popup" href="#">Visit Site</a> <a class="btn btn-secondary js-close-popup" href="#">Cancel</a></p> </div> </div> <div class="popup" id="inter"> <div class="wrapper"><a class="close js-close-popup" href="#">×</a> <p class="h3">You are now leaving OXLUMO.com</p> <p>Links to all outside sites are provided as a reference for our visitors. 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