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class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/31221751/The_use_of_an_air_bubble_curtain_to_reduce_the_received_sound_levels_for_harbor_porpoises_Phocoena_phocoena_">The use of an air bubble curtain to reduce the received sound levels for harbor porpoises (Phocoena phocoena)</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/UrsulaSiebert">Ursula Siebert</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://lboro.academia.edu/PaulLepper">Paul Lepper</a></span></div><div class="wp-workCard_item"><span>The Journal of the Acoustical Society of America</span><span>, 2011</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">In December 2005 construction work was started to replace a harbor wall in Kerteminde harbor, Den...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">In December 2005 construction work was started to replace a harbor wall in Kerteminde harbor, Denmark. A total of 175 wooden piles were piled into the ground at the waters edge over a period of 3 months. During the same period three harbor porpoises were housed in a marine mammal facility on the opposite side of the harbor. All animals showed strong avoidance reactions after the start of the piling activities. As a measure to reduce the sound exposure for the animals an air bubble curtain was constructed and operated in a direct path between the piling site and the opening of the animals&#x27; semi-natural pool. The sound attenuation effect achieved with this system was determined by quantitative comparison of pile driving impulses simultaneously measured in front of and behind the active air bubble curtain. Mean levels of sound attenuation over a sequence of 95 consecutive pile strikes were 14 dB (standard deviation (s.d.) 3.4 dB) for peak to peak values and 13 dB (s.d. 2.5 dB) for...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="4e4294101f6fa8f157bf6249ebc8fcbc" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":51633654,"asset_id":31221751,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/51633654/download_file?st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="31221751"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="31221751"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 31221751; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=31221751]").text(description); $(".js-view-count[data-work-id=31221751]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 31221751; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='31221751']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 31221751, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "4e4294101f6fa8f157bf6249ebc8fcbc" } } $('.js-work-strip[data-work-id=31221751]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":31221751,"title":"The use of an air bubble curtain to reduce the received sound levels for harbor porpoises (Phocoena phocoena)","translated_title":"","metadata":{"abstract":"In December 2005 construction work was started to replace a harbor wall in Kerteminde harbor, Denmark. 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class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204078/Phocine_distemper_virus_PDV_seroprevalence_as_predictor_for_future_outbreaks_in_harbour_seals">Phocine distemper virus (PDV) seroprevalence as predictor for future outbreaks in harbour seals</a></div><div class="wp-workCard_item"><span>Veterinary microbiology</span><span>, 2016</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Phocine distemper virus (PDV) infections caused the two most pronounced mass mortalities in marin...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Phocine distemper virus (PDV) infections caused the two most pronounced mass mortalities in marine mammals documented in the past century. During the two outbreaks, 23,000 and 30,000 harbour seals (Phoca vitulina), died in 1988/1989 and 2002 across populations in the Wadden Sea and adjacent waters, respectively. To follow the mechanism and development of disease spreading, the dynamics of Morbillivirus-specific antibodies in harbour seal populations in German and Danish waters were examined. 522 serum samples of free-ranging harbour seals of different ages were sampled between 1990 and 2014. By standard neutralisation assays, Morbillivirus-specific antibodies were detected, using either the PDV isolate 2558/Han 88 or the related canine distemper virus (CDV) strain Onderstepoort. A total of 159 (30.5%) of the harbour seals were seropositive. Annual seroprevalence rates showed an undulating course: Peaks were seen in the post-epidemic years 1990/1991 and 2002/2003. Following each PDV ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204078"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204078"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204078; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204078]").text(description); $(".js-view-count[data-work-id=29204078]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204078; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204078']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204078, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=29204078]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204078,"title":"Phocine distemper virus (PDV) seroprevalence as predictor for future outbreaks in harbour seals","translated_title":"","metadata":{"abstract":"Phocine distemper virus (PDV) infections caused the two most pronounced mass mortalities in marine mammals documented in the past century. During the two outbreaks, 23,000 and 30,000 harbour seals (Phoca vitulina), died in 1988/1989 and 2002 across populations in the Wadden Sea and adjacent waters, respectively. To follow the mechanism and development of disease spreading, the dynamics of Morbillivirus-specific antibodies in harbour seal populations in German and Danish waters were examined. 522 serum samples of free-ranging harbour seals of different ages were sampled between 1990 and 2014. By standard neutralisation assays, Morbillivirus-specific antibodies were detected, using either the PDV isolate 2558/Han 88 or the related canine distemper virus (CDV) strain Onderstepoort. A total of 159 (30.5%) of the harbour seals were seropositive. Annual seroprevalence rates showed an undulating course: Peaks were seen in the post-epidemic years 1990/1991 and 2002/2003. Following each PDV ...","publication_date":{"day":null,"month":null,"year":2016,"errors":{}},"publication_name":"Veterinary microbiology"},"translated_abstract":"Phocine distemper virus (PDV) infections caused the two most pronounced mass mortalities in marine mammals documented in the past century. During the two outbreaks, 23,000 and 30,000 harbour seals (Phoca vitulina), died in 1988/1989 and 2002 across populations in the Wadden Sea and adjacent waters, respectively. To follow the mechanism and development of disease spreading, the dynamics of Morbillivirus-specific antibodies in harbour seal populations in German and Danish waters were examined. 522 serum samples of free-ranging harbour seals of different ages were sampled between 1990 and 2014. By standard neutralisation assays, Morbillivirus-specific antibodies were detected, using either the PDV isolate 2558/Han 88 or the related canine distemper virus (CDV) strain Onderstepoort. A total of 159 (30.5%) of the harbour seals were seropositive. Annual seroprevalence rates showed an undulating course: Peaks were seen in the post-epidemic years 1990/1991 and 2002/2003. Following each PDV ...","internal_url":"https://www.academia.edu/29204078/Phocine_distemper_virus_PDV_seroprevalence_as_predictor_for_future_outbreaks_in_harbour_seals","translated_internal_url":"","created_at":"2016-10-16T22:58:01.510-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":30859474,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Phocine_distemper_virus_PDV_seroprevalence_as_predictor_for_future_outbreaks_in_harbour_seals","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":30859474,"first_name":"Ursula","middle_initials":null,"last_name":"Siebert","page_name":"UrsulaSiebert","domain_name":"independent","created_at":"2015-05-07T06:42:56.107-07:00","display_name":"Ursula Siebert","url":"https://independent.academia.edu/UrsulaSiebert"},"attachments":[],"research_interests":[{"id":159,"name":"Microbiology","url":"https://www.academia.edu/Documents/in/Microbiology"},{"id":3037,"name":"Veterinary Microbiology","url":"https://www.academia.edu/Documents/in/Veterinary_Microbiology"},{"id":644860,"name":"Veterinary Sciences","url":"https://www.academia.edu/Documents/in/Veterinary_Sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204077"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204077/Temporal_and_Spatial_Trends_of_Perfluoroalkylated_Substances_in_Harbour_Porpoise_Phocoena_phocoena_Livers_from_Northern_Europe_1991_2008"><img alt="Research paper thumbnail of Temporal and Spatial Trends of Perfluoroalkylated Substances in Harbour Porpoise (Phocoena phocoena) Livers from Northern Europe, 1991 - 2008" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204077/Temporal_and_Spatial_Trends_of_Perfluoroalkylated_Substances_in_Harbour_Porpoise_Phocoena_phocoena_Livers_from_Northern_Europe_1991_2008">Temporal and Spatial Trends of Perfluoroalkylated Substances in Harbour Porpoise (Phocoena phocoena) Livers from Northern Europe, 1991 - 2008</a></div><div class="wp-workCard_item"><span>Science of the Total Environment</span><span>, Mar 1, 2012</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">ABSTRACT Long-term temporal trends (1991–2008) and spatial differences of perfluoroalkylated subs...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">ABSTRACT Long-term temporal trends (1991–2008) and spatial differences of perfluoroalkylated substances (PFASs) were investigated in harbor porpoise (Phocoena phocoena) liver samples of juvenile females from the Baltic and North Sea. Additionally, spatial differences between the populations in the Baltic Sea and Atlantic Ocean (i.e. Iceland and Norway) and the influence of the body mass, age and sex on the PFAS concentrations were examined. Perfluorooctane sulfonate (PFOS) was the predominant compound with a concentration range of 160–2425 ng/g wet weight (ww), followed by perfluorooctane sulfonamide (PFOSA, 1–237 ng/g ww) and perfluoroundecanoate (PFUnA, 3–124 ng/g ww). In terms of temporal trends, perfluoroalkyl sulfonates (PFSAs) and PFOSA concentrations decreased over time, while, conversely, the C9–C13 perfluoroalkyl carboxylate (PFCA) concentrations increased. Spatial distribution of the contaminant concentrations showed consistently higher concentrations in the Baltic Sea and lowest concentrations in the Icelandic population of the Atlantic Ocean.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204077"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204077"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204077; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204077]").text(description); $(".js-view-count[data-work-id=29204077]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204077; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204077']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204077, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=29204077]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204077,"title":"Temporal and Spatial Trends of Perfluoroalkylated Substances in Harbour Porpoise (Phocoena phocoena) Livers from Northern Europe, 1991 - 2008","translated_title":"","metadata":{"abstract":"ABSTRACT Long-term temporal trends (1991–2008) and spatial differences of perfluoroalkylated substances (PFASs) were investigated in harbor porpoise (Phocoena phocoena) liver samples of juvenile females from the Baltic and North Sea. 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Perfluorooctane sulfonate (PFOS) was the predominant compound with a concentration range of 160–2425 ng/g wet weight (ww), followed by perfluorooctane sulfonamide (PFOSA, 1–237 ng/g ww) and perfluoroundecanoate (PFUnA, 3–124 ng/g ww). In terms of temporal trends, perfluoroalkyl sulfonates (PFSAs) and PFOSA concentrations decreased over time, while, conversely, the C9–C13 perfluoroalkyl carboxylate (PFCA) concentrations increased. Spatial distribution of the contaminant concentrations showed consistently higher concentrations in the Baltic Sea and lowest concentrations in the Icelandic population of the Atlantic Ocean.","internal_url":"https://www.academia.edu/29204077/Temporal_and_Spatial_Trends_of_Perfluoroalkylated_Substances_in_Harbour_Porpoise_Phocoena_phocoena_Livers_from_Northern_Europe_1991_2008","translated_internal_url":"","created_at":"2016-10-16T22:58:01.371-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":30859474,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Temporal_and_Spatial_Trends_of_Perfluoroalkylated_Substances_in_Harbour_Porpoise_Phocoena_phocoena_Livers_from_Northern_Europe_1991_2008","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":30859474,"first_name":"Ursula","middle_initials":null,"last_name":"Siebert","page_name":"UrsulaSiebert","domain_name":"independent","created_at":"2015-05-07T06:42:56.107-07:00","display_name":"Ursula Siebert","url":"https://independent.academia.edu/UrsulaSiebert"},"attachments":[],"research_interests":[{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary"}],"urls":[]}, dispatcherData: dispatcherData }); 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Cetacean morbilliviruses and papillomaviruses as well as Brucella spp. and Toxoplasma gondii are thought to interfere with population abundance by inducing high mortalities, lowering reproductive success or by synergistically increasing the virulence of other diseases. Severe cases of lobomycosis and lobomycosis-like disease (LLD) may contribute to the death of some dolphins. The zoonotic hazard of marine mammal brucellosis and toxoplasmosis may have been underestimated, attributable to frequent misdiagnoses and underreporting, particularly in developing countries and remote areas where carcass handling without protective gear and human consumption of fresh cetacean products are commonplace. Environmental factors seem to play a role in the emergence and pathogenicity of morbillivirus epidemics, lobomycosis/LLD, toxoplasmosis, poxvirus-associated tattoo skin disease and, in harbour porpoises, infectious diseases of multifactorial aetiology. Inshore and estuarine cetaceans incur higher risks than pelagic cetaceans due to habitats often severely altered by anthropogenic factors such as chemical and biological contamination, direct and indirect fisheries interactions, traumatic injuries from vessel collisions and climate change.","publication_date":{"day":1,"month":6,"year":2008,"errors":{}},"grobid_abstract_attachment_id":49655270},"translated_abstract":null,"internal_url":"https://www.academia.edu/29204076/Emerging_and_recurring_diseases_in_cetaceans_worldwide_and_the_role_of_environmental_stressors","translated_internal_url":"","created_at":"2016-10-16T22:58:01.221-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":30859474,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":49655270,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/49655270/thumbnails/1.jpg","file_name":"Emerging_and_recurring_diseases_in_cetac20161016-6506-1txy4fq.pdf","download_url":"https://www.academia.edu/attachments/49655270/download_file?st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Emerging_and_recurring_diseases_in_cetac.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/49655270/Emerging_and_recurring_diseases_in_cetac20161016-6506-1txy4fq-libre.pdf?1476684347=\u0026response-content-disposition=attachment%3B+filename%3DEmerging_and_recurring_diseases_in_cetac.pdf\u0026Expires=1732725922\u0026Signature=TKspWbGXJgF3dD0gKOpeNkxHkZDfMjKAzPUmXSBAsJCBXvjMsDC-sxBMVZN10Hwoq5Fa0PF0iJJ47yYXtEgGxTU67u71zjH2xLETFBsBgIZZYetjmnU7HnhYPMBuqnxY2uZYe1xJmUmSLABTuVcE00S8js80YjiK3tZwHuri1EoPf3V2d6fqtVqjqw8npLrdEm9OCelpfXkLQFZzZDcgFwMh8uN9miux114vCYvbeqZUQ8OaSz96tXA8-7~otTFxTICwZ3wFuEq6LUP7Ko1sj~zLMxriI97XGZMlWX-pGUOLP9dyyKxaOHKn6pBgL352zV38fBdjl8eZ~XCfwe94Cg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Emerging_and_recurring_diseases_in_cetaceans_worldwide_and_the_role_of_environmental_stressors","translated_slug":"","page_count":15,"language":"en","content_type":"Work","owner":{"id":30859474,"first_name":"Ursula","middle_initials":null,"last_name":"Siebert","page_name":"UrsulaSiebert","domain_name":"independent","created_at":"2015-05-07T06:42:56.107-07:00","display_name":"Ursula Siebert","url":"https://independent.academia.edu/UrsulaSiebert"},"attachments":[{"id":49655270,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/49655270/thumbnails/1.jpg","file_name":"Emerging_and_recurring_diseases_in_cetac20161016-6506-1txy4fq.pdf","download_url":"https://www.academia.edu/attachments/49655270/download_file?st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Emerging_and_recurring_diseases_in_cetac.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/49655270/Emerging_and_recurring_diseases_in_cetac20161016-6506-1txy4fq-libre.pdf?1476684347=\u0026response-content-disposition=attachment%3B+filename%3DEmerging_and_recurring_diseases_in_cetac.pdf\u0026Expires=1732725922\u0026Signature=TKspWbGXJgF3dD0gKOpeNkxHkZDfMjKAzPUmXSBAsJCBXvjMsDC-sxBMVZN10Hwoq5Fa0PF0iJJ47yYXtEgGxTU67u71zjH2xLETFBsBgIZZYetjmnU7HnhYPMBuqnxY2uZYe1xJmUmSLABTuVcE00S8js80YjiK3tZwHuri1EoPf3V2d6fqtVqjqw8npLrdEm9OCelpfXkLQFZzZDcgFwMh8uN9miux114vCYvbeqZUQ8OaSz96tXA8-7~otTFxTICwZ3wFuEq6LUP7Ko1sj~zLMxriI97XGZMlWX-pGUOLP9dyyKxaOHKn6pBgL352zV38fBdjl8eZ~XCfwe94Cg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[],"urls":[]}, dispatcherData: dispatcherData }); 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The interaction between toxicological results (Zn, Cd, Cu, Fe, Se, Hg), stable isotope data (δ 13 C and δ 15 N) and the most common pathological findings, namely emaciation and lesions of the respiratory system, were investigated in 132 porpoises collected along the coasts of northern France, Belgium, Germany, Denmark, Iceland and Norway between 1994 and 2001. The body condition of harbour porpoises stranded on the French, Belgian and German coasts was poor compared to that of by-catch individuals from Iceland and Norway, as reflected by blubber thickness and hepatic to total body-mass ratio. High Zn and Hg concentrations were observed in some porpoises collected along the southern North Sea coast compared to by-catch individuals from Iceland, Norway and the Baltic Sea. Increasing Zn levels were observed with deteriorating health condition (emaciation and bronchopneumonia), while Hg increases were not significant. The increases were not related to shrinking liver mass which remained unchanged. These observations indicate a general redistribution of trace metals within the organs (muscles and blubber to liver), as a result of protein and lipid catabolism. Muscle δ 13 C and δ 15 N values remained unchanged with deteriorating body condition. Cd concentrations were associated only with age and low δ 15 N values, indicating that high Cd concentrations in Iceland and Norway porpoises may be partly diet-related, i.e. a result of Cd contaminated prey.","publication_date":{"day":null,"month":null,"year":2005,"errors":{}},"grobid_abstract_attachment_id":49655266},"translated_abstract":null,"internal_url":"https://www.academia.edu/29204075/Ecological_and_pathological_factors_related_to_trace_metal_concentrations_in_harbour_seal_Phoca_vitulina_in_the_North_Sea","translated_internal_url":"","created_at":"2016-10-16T22:58:01.026-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":30859474,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":49655266,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/49655266/thumbnails/1.jpg","file_name":"Ecological_and_pathological_factors_rela20161016-20451-cfkez8.pdf","download_url":"https://www.academia.edu/attachments/49655266/download_file?st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Ecological_and_pathological_factors_rela.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/49655266/Ecological_and_pathological_factors_rela20161016-20451-cfkez8-libre.pdf?1476684348=\u0026response-content-disposition=attachment%3B+filename%3DEcological_and_pathological_factors_rela.pdf\u0026Expires=1732725922\u0026Signature=TiNTb7Hyk3Zad4e55LmApmXQFOfuyBzlfmaOMn6TEsv958WIRhAhcO7YKj2EFYL8wPJNn~jN9uXVHglkyuohwrcELJkgXeZAgRj2OuJN2FJT037zgXmjhaiTp5JE6bXdFPrUhNBGu2gCIuLCNlhS4Rlv1iClcIDqgomHbE35MK7pP1JkRo0NBNWfNjT2KcyNsCgpEUsopj1o1ZdR2Tf1RSxR8x29fzggsKbOg1WxmYWySG1sWcHQm2juFu9yONnKG4iXrbGJg96btOSyvZ-z8DfsPrCMgQ9wNBjC1coelDmblTlexhz~3JtPzkoDqRCuRq1Aa~PXCFijn~ft2E3Nog__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Ecological_and_pathological_factors_related_to_trace_metal_concentrations_in_harbour_seal_Phoca_vitulina_in_the_North_Sea","translated_slug":"","page_count":13,"language":"en","content_type":"Work","owner":{"id":30859474,"first_name":"Ursula","middle_initials":null,"last_name":"Siebert","page_name":"UrsulaSiebert","domain_name":"independent","created_at":"2015-05-07T06:42:56.107-07:00","display_name":"Ursula Siebert","url":"https://independent.academia.edu/UrsulaSiebert"},"attachments":[{"id":49655266,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/49655266/thumbnails/1.jpg","file_name":"Ecological_and_pathological_factors_rela20161016-20451-cfkez8.pdf","download_url":"https://www.academia.edu/attachments/49655266/download_file?st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Ecological_and_pathological_factors_rela.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/49655266/Ecological_and_pathological_factors_rela20161016-20451-cfkez8-libre.pdf?1476684348=\u0026response-content-disposition=attachment%3B+filename%3DEcological_and_pathological_factors_rela.pdf\u0026Expires=1732725922\u0026Signature=TiNTb7Hyk3Zad4e55LmApmXQFOfuyBzlfmaOMn6TEsv958WIRhAhcO7YKj2EFYL8wPJNn~jN9uXVHglkyuohwrcELJkgXeZAgRj2OuJN2FJT037zgXmjhaiTp5JE6bXdFPrUhNBGu2gCIuLCNlhS4Rlv1iClcIDqgomHbE35MK7pP1JkRo0NBNWfNjT2KcyNsCgpEUsopj1o1ZdR2Tf1RSxR8x29fzggsKbOg1WxmYWySG1sWcHQm2juFu9yONnKG4iXrbGJg96btOSyvZ-z8DfsPrCMgQ9wNBjC1coelDmblTlexhz~3JtPzkoDqRCuRq1Aa~PXCFijn~ft2E3Nog__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":173,"name":"Zoology","url":"https://www.academia.edu/Documents/in/Zoology"},{"id":9846,"name":"Ecology","url":"https://www.academia.edu/Documents/in/Ecology"},{"id":224144,"name":"Pollutants","url":"https://www.academia.edu/Documents/in/Pollutants"}],"urls":[{"id":7649521,"url":"http://orbi.ulg.ac.be/handle/2268/72654"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204074"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204074/Seals_at_sea_%C3%A2_modelling_seal_distribution_in_the_German_Bight_based_on_aerial_survey_data"><img alt="Research paper thumbnail of Seals at sea â�� modelling seal distribution in the German Bight based on aerial survey data" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204074/Seals_at_sea_%C3%A2_modelling_seal_distribution_in_the_German_Bight_based_on_aerial_survey_data">Seals at sea â�� modelling seal distribution in the German Bight based on aerial survey data</a></div><div class="wp-workCard_item"><span>Marine Biology 156 Pp 811 820</span><span>, 2009</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204074"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204074"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204074; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204073"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204073/Isocyamus_delphinii_First_record_of_whale_lice_on_a_harbour_porpoise_Phocoena_phocoena_from_German_waters"><img alt="Research paper thumbnail of Isocyamus delphinii: First record of whale-lice on a harbour porpoise (Phocoena phocoena) from German waters" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204073/Isocyamus_delphinii_First_record_of_whale_lice_on_a_harbour_porpoise_Phocoena_phocoena_from_German_waters">Isocyamus delphinii: First record of whale-lice on a harbour porpoise (Phocoena phocoena) from German waters</a></div><div class="wp-workCard_item"><span>Veterinary Record 161 Pp 526 528</span><span>, 2007</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204073"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204073"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204073; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204073]").text(description); $(".js-view-count[data-work-id=29204073]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204073; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204073']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204073, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=29204073]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204073,"title":"Isocyamus delphinii: First record of whale-lice on a harbour porpoise (Phocoena phocoena) from German waters","translated_title":"","metadata":{"publication_date":{"day":null,"month":null,"year":2007,"errors":{}},"publication_name":"Veterinary Record 161 Pp 526 528"},"translated_abstract":null,"internal_url":"https://www.academia.edu/29204073/Isocyamus_delphinii_First_record_of_whale_lice_on_a_harbour_porpoise_Phocoena_phocoena_from_German_waters","translated_internal_url":"","created_at":"2016-10-16T22:58:00.623-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":30859474,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Isocyamus_delphinii_First_record_of_whale_lice_on_a_harbour_porpoise_Phocoena_phocoena_from_German_waters","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":30859474,"first_name":"Ursula","middle_initials":null,"last_name":"Siebert","page_name":"UrsulaSiebert","domain_name":"independent","created_at":"2015-05-07T06:42:56.107-07:00","display_name":"Ursula Siebert","url":"https://independent.academia.edu/UrsulaSiebert"},"attachments":[],"research_interests":[],"urls":[{"id":7649519,"url":"http://oceanrep.geomar.de/11245/"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204071"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204071/Viral_protein_expression_and_phenotyping_of_inflammatory_responses_in_the_central_nervous_system_of_phocine_distemper_virus_infected_harbor_seals_Phoca_vitulina_"><img alt="Research paper thumbnail of Viral protein expression and phenotyping of inflammatory responses in the central nervous system of phocine distemper virus-infected harbor seals ( Phoca vitulina)" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204071/Viral_protein_expression_and_phenotyping_of_inflammatory_responses_in_the_central_nervous_system_of_phocine_distemper_virus_infected_harbor_seals_Phoca_vitulina_">Viral protein expression and phenotyping of inflammatory responses in the central nervous system of phocine distemper virus-infected harbor seals ( Phoca vitulina)</a></div><div class="wp-workCard_item"><span>Veterinary Microbiology</span><span>, Mar 1, 2010</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The central nervous system (CNS) represents an important target organ of the phocine distemper vi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The central nervous system (CNS) represents an important target organ of the phocine distemper virus (PDV). The aim of the present study was to characterize pathological changes in the CNS of harbor seals suffering from natural PDV-infection. The distribution of virus protein and mRNA was investigated by immunohistochemistry (IHC) and in situ hybridization, respectively. In addition, inflammatory and glial cells were characterized by IHC. Polioencephalitis with glial activation, neuronal death and perivascular mononuclear infiltrations in the cerebral cortex was the main histopathological finding. Inflammatory responses, dominated by CD3(+) T-cells and activated microglia/macrophages were associated with a prominent MHC-II upregulation within the CNS. Viral protein was found predominantly in neurofilament-expressing neurons within inflamed areas as demonstrated by immunohistochemical double-labeling. Morbillivirus nucleo-, phospho-, matrix-, fusion- and hemagglutinin-proteins were found in CNS-lesions. The expressions of viral matrix- and fusion-proteins were reduced in severely inflamed plaques. Comparison of viral protein and mRNA expression revealed a diminished amount of viral phosphoprotein preferentially associated with perivascular inflammation. In summary, CNS-lesions in PDV-infected seals are similar to canine distemper virus-induced acute polioencephalitis in dogs and measles virus inclusion body polioencephalitis in men, respectively.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204071"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204071"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204071; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204071]").text(description); $(".js-view-count[data-work-id=29204071]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204071; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204071']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204071, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=29204071]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204071,"title":"Viral protein expression and phenotyping of inflammatory responses in the central nervous system of phocine distemper virus-infected harbor seals ( Phoca vitulina)","translated_title":"","metadata":{"abstract":"The central nervous system (CNS) represents an important target organ of the phocine distemper virus (PDV). The aim of the present study was to characterize pathological changes in the CNS of harbor seals suffering from natural PDV-infection. The distribution of virus protein and mRNA was investigated by immunohistochemistry (IHC) and in situ hybridization, respectively. In addition, inflammatory and glial cells were characterized by IHC. Polioencephalitis with glial activation, neuronal death and perivascular mononuclear infiltrations in the cerebral cortex was the main histopathological finding. Inflammatory responses, dominated by CD3(+) T-cells and activated microglia/macrophages were associated with a prominent MHC-II upregulation within the CNS. Viral protein was found predominantly in neurofilament-expressing neurons within inflamed areas as demonstrated by immunohistochemical double-labeling. Morbillivirus nucleo-, phospho-, matrix-, fusion- and hemagglutinin-proteins were found in CNS-lesions. The expressions of viral matrix- and fusion-proteins were reduced in severely inflamed plaques. Comparison of viral protein and mRNA expression revealed a diminished amount of viral phosphoprotein preferentially associated with perivascular inflammation. In summary, CNS-lesions in PDV-infected seals are similar to canine distemper virus-induced acute polioencephalitis in dogs and measles virus inclusion body polioencephalitis in men, respectively.","publication_date":{"day":1,"month":3,"year":2010,"errors":{}},"publication_name":"Veterinary Microbiology"},"translated_abstract":"The central nervous system (CNS) represents an important target organ of the phocine distemper virus (PDV). The aim of the present study was to characterize pathological changes in the CNS of harbor seals suffering from natural PDV-infection. The distribution of virus protein and mRNA was investigated by immunohistochemistry (IHC) and in situ hybridization, respectively. In addition, inflammatory and glial cells were characterized by IHC. Polioencephalitis with glial activation, neuronal death and perivascular mononuclear infiltrations in the cerebral cortex was the main histopathological finding. Inflammatory responses, dominated by CD3(+) T-cells and activated microglia/macrophages were associated with a prominent MHC-II upregulation within the CNS. Viral protein was found predominantly in neurofilament-expressing neurons within inflamed areas as demonstrated by immunohistochemical double-labeling. Morbillivirus nucleo-, phospho-, matrix-, fusion- and hemagglutinin-proteins were found in CNS-lesions. The expressions of viral matrix- and fusion-proteins were reduced in severely inflamed plaques. Comparison of viral protein and mRNA expression revealed a diminished amount of viral phosphoprotein preferentially associated with perivascular inflammation. In summary, CNS-lesions in PDV-infected seals are similar to canine distemper virus-induced acute polioencephalitis in dogs and measles virus inclusion body polioencephalitis in men, respectively.","internal_url":"https://www.academia.edu/29204071/Viral_protein_expression_and_phenotyping_of_inflammatory_responses_in_the_central_nervous_system_of_phocine_distemper_virus_infected_harbor_seals_Phoca_vitulina_","translated_internal_url":"","created_at":"2016-10-16T22:58:00.412-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":30859474,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Viral_protein_expression_and_phenotyping_of_inflammatory_responses_in_the_central_nervous_system_of_phocine_distemper_virus_infected_harbor_seals_Phoca_vitulina_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":30859474,"first_name":"Ursula","middle_initials":null,"last_name":"Siebert","page_name":"UrsulaSiebert","domain_name":"independent","created_at":"2015-05-07T06:42:56.107-07:00","display_name":"Ursula Siebert","url":"https://independent.academia.edu/UrsulaSiebert"},"attachments":[],"research_interests":[{"id":159,"name":"Microbiology","url":"https://www.academia.edu/Documents/in/Microbiology"},{"id":3037,"name":"Veterinary Microbiology","url":"https://www.academia.edu/Documents/in/Veterinary_Microbiology"},{"id":12071,"name":"Immunohistochemistry","url":"https://www.academia.edu/Documents/in/Immunohistochemistry"},{"id":35414,"name":"Veterinary","url":"https://www.academia.edu/Documents/in/Veterinary"},{"id":37836,"name":"In Situ Hybridization","url":"https://www.academia.edu/Documents/in/In_Situ_Hybridization"},{"id":39977,"name":"Measles Virus","url":"https://www.academia.edu/Documents/in/Measles_Virus"},{"id":78467,"name":"Cerebral Cortex","url":"https://www.academia.edu/Documents/in/Cerebral_Cortex"},{"id":130117,"name":"Glial Cell","url":"https://www.academia.edu/Documents/in/Glial_Cell"},{"id":147195,"name":"Central Nervous System","url":"https://www.academia.edu/Documents/in/Central_Nervous_System"},{"id":213897,"name":"Phenotype","url":"https://www.academia.edu/Documents/in/Phenotype"},{"id":284067,"name":"Inclusion Bodies","url":"https://www.academia.edu/Documents/in/Inclusion_Bodies"},{"id":310960,"name":"mRna expression levels","url":"https://www.academia.edu/Documents/in/mRna_expression_levels"},{"id":394656,"name":"Phocine Distemper Virus","url":"https://www.academia.edu/Documents/in/Phocine_Distemper_Virus"},{"id":396278,"name":"Neuronal Death","url":"https://www.academia.edu/Documents/in/Neuronal_Death"},{"id":501806,"name":"Protein Expression","url":"https://www.academia.edu/Documents/in/Protein_Expression"},{"id":644860,"name":"Veterinary Sciences","url":"https://www.academia.edu/Documents/in/Veterinary_Sciences"},{"id":746733,"name":"Phoca Vitulina","url":"https://www.academia.edu/Documents/in/Phoca_Vitulina"},{"id":900875,"name":"Canine Distemper Virus","url":"https://www.academia.edu/Documents/in/Canine_Distemper_Virus"},{"id":985648,"name":"Phoca","url":"https://www.academia.edu/Documents/in/Phoca"},{"id":1109079,"name":"Encephalitis","url":"https://www.academia.edu/Documents/in/Encephalitis"},{"id":1159037,"name":"Fusion Protein","url":"https://www.academia.edu/Documents/in/Fusion_Protein"},{"id":2159933,"name":"Distemper","url":"https://www.academia.edu/Documents/in/Distemper"},{"id":2454817,"name":"Inflammatory response","url":"https://www.academia.edu/Documents/in/Inflammatory_response"}],"urls":[{"id":7649517,"url":"http://cat.inist.fr/?aModele=afficheN\u0026cpsidt=23264887"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204068"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204068/Spatiotemporal_analysis_of_the_genetic_diversity_of_seal_influenza_A_H10N7_virus_Northwestern_Europe"><img alt="Research paper thumbnail of Spatiotemporal analysis of the genetic diversity of seal influenza A(H10N7) virus, Northwestern Europe" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204068/Spatiotemporal_analysis_of_the_genetic_diversity_of_seal_influenza_A_H10N7_virus_Northwestern_Europe">Spatiotemporal analysis of the genetic diversity of seal influenza A(H10N7) virus, Northwestern Europe</a></div><div class="wp-workCard_item"><span>Journal of Virology</span><span>, 2016</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Influenza A viruses are major pathogens for humans, domestic animals and wildlife that cross the ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Influenza A viruses are major pathogens for humans, domestic animals and wildlife that cross the species barrier occasionally. In spring 2014, increased mortality of harbor seals (Phoca vitulina) was reported in Sweden and Denmark, associated with infection with an influenza A(H10N7) virus. Within a few months, this virus spread to seals of the coastal waters of Germany and the Netherlands, causing the death of thousands of animals. Genetic analysis of the hemagglutinin (HA) and neuraminidase (NA) genes of this seal influenza A(H10N7) virus revealed that it was most closely related to various avian influenza A(H10N7) viruses. The collection of samples from infected seals during the course of the outbreak provided an unique opportunity to follow the adaptation of this avian virus to its new seal host. Sequence data was obtained from samples collected from 41 different seals from four different countries between April 2014 and January 2015 using Sanger sequencing and next-generation sequencing to describe the molecular epidemiology of the seal influenza A(H10N7) virus. The majority of sequence variation occurred in the HA gene, and some mutations corresponded with amino acid changes not found in H10 viruses isolated from Eurasian birds. Also, sequence variation in the HA gene was greater at the beginning than at the end of the epidemic, when a number of the mutations observed earlier had been fixed. These results imply that when an avian influenza virus jumps the species barrier from birds to seals, amino acid changes in the HA may occur rapidly and are important for virus adaptation to its new mammalian host. Influenza A viruses are major pathogens for humans, domestic animals and wildlife. In addition to the continuous circulation of influenza A viruses among various host species, cross-species transmission of influenza A viruses occurs occasionally. Wild waterfowl and shorebirds are the main reservoir for most influenza A virus subtypes, and spillover of influenza A viruses from birds to humans or other mammalian species may result in major outbreaks. In the present study, various sequencing methods were used to elucidate the genetic changes that occurred after the introduction and subsequent spread of an avian influenza A(H10N7) among harbor seals of Northwestern Europe using various samples collected during the outbreak. Such detailed knowledge of genetic changes necessary for introduction and adaptation of avian influenza A viruses to mammalian hosts is important for a rapid risk assessment of such viruses soon after they cross the species barrier.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204068"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204068"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204068; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204068]").text(description); $(".js-view-count[data-work-id=29204068]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204068; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204068']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204068, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=29204068]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204068,"title":"Spatiotemporal analysis of the genetic diversity of seal influenza A(H10N7) virus, Northwestern Europe","translated_title":"","metadata":{"abstract":"Influenza A viruses are major pathogens for humans, domestic animals and wildlife that cross the species barrier occasionally. In spring 2014, increased mortality of harbor seals (Phoca vitulina) was reported in Sweden and Denmark, associated with infection with an influenza A(H10N7) virus. Within a few months, this virus spread to seals of the coastal waters of Germany and the Netherlands, causing the death of thousands of animals. Genetic analysis of the hemagglutinin (HA) and neuraminidase (NA) genes of this seal influenza A(H10N7) virus revealed that it was most closely related to various avian influenza A(H10N7) viruses. The collection of samples from infected seals during the course of the outbreak provided an unique opportunity to follow the adaptation of this avian virus to its new seal host. Sequence data was obtained from samples collected from 41 different seals from four different countries between April 2014 and January 2015 using Sanger sequencing and next-generation sequencing to describe the molecular epidemiology of the seal influenza A(H10N7) virus. The majority of sequence variation occurred in the HA gene, and some mutations corresponded with amino acid changes not found in H10 viruses isolated from Eurasian birds. Also, sequence variation in the HA gene was greater at the beginning than at the end of the epidemic, when a number of the mutations observed earlier had been fixed. These results imply that when an avian influenza virus jumps the species barrier from birds to seals, amino acid changes in the HA may occur rapidly and are important for virus adaptation to its new mammalian host. Influenza A viruses are major pathogens for humans, domestic animals and wildlife. In addition to the continuous circulation of influenza A viruses among various host species, cross-species transmission of influenza A viruses occurs occasionally. Wild waterfowl and shorebirds are the main reservoir for most influenza A virus subtypes, and spillover of influenza A viruses from birds to humans or other mammalian species may result in major outbreaks. In the present study, various sequencing methods were used to elucidate the genetic changes that occurred after the introduction and subsequent spread of an avian influenza A(H10N7) among harbor seals of Northwestern Europe using various samples collected during the outbreak. Such detailed knowledge of genetic changes necessary for introduction and adaptation of avian influenza A viruses to mammalian hosts is important for a rapid risk assessment of such viruses soon after they cross the species barrier.","publication_date":{"day":null,"month":null,"year":2016,"errors":{}},"publication_name":"Journal of Virology"},"translated_abstract":"Influenza A viruses are major pathogens for humans, domestic animals and wildlife that cross the species barrier occasionally. In spring 2014, increased mortality of harbor seals (Phoca vitulina) was reported in Sweden and Denmark, associated with infection with an influenza A(H10N7) virus. Within a few months, this virus spread to seals of the coastal waters of Germany and the Netherlands, causing the death of thousands of animals. Genetic analysis of the hemagglutinin (HA) and neuraminidase (NA) genes of this seal influenza A(H10N7) virus revealed that it was most closely related to various avian influenza A(H10N7) viruses. The collection of samples from infected seals during the course of the outbreak provided an unique opportunity to follow the adaptation of this avian virus to its new seal host. Sequence data was obtained from samples collected from 41 different seals from four different countries between April 2014 and January 2015 using Sanger sequencing and next-generation sequencing to describe the molecular epidemiology of the seal influenza A(H10N7) virus. The majority of sequence variation occurred in the HA gene, and some mutations corresponded with amino acid changes not found in H10 viruses isolated from Eurasian birds. Also, sequence variation in the HA gene was greater at the beginning than at the end of the epidemic, when a number of the mutations observed earlier had been fixed. These results imply that when an avian influenza virus jumps the species barrier from birds to seals, amino acid changes in the HA may occur rapidly and are important for virus adaptation to its new mammalian host. Influenza A viruses are major pathogens for humans, domestic animals and wildlife. In addition to the continuous circulation of influenza A viruses among various host species, cross-species transmission of influenza A viruses occurs occasionally. Wild waterfowl and shorebirds are the main reservoir for most influenza A virus subtypes, and spillover of influenza A viruses from birds to humans or other mammalian species may result in major outbreaks. In the present study, various sequencing methods were used to elucidate the genetic changes that occurred after the introduction and subsequent spread of an avian influenza A(H10N7) among harbor seals of Northwestern Europe using various samples collected during the outbreak. Such detailed knowledge of genetic changes necessary for introduction and adaptation of avian influenza A viruses to mammalian hosts is important for a rapid risk assessment of such viruses soon after they cross the species barrier.","internal_url":"https://www.academia.edu/29204068/Spatiotemporal_analysis_of_the_genetic_diversity_of_seal_influenza_A_H10N7_virus_Northwestern_Europe","translated_internal_url":"","created_at":"2016-10-16T22:58:00.169-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":30859474,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Spatiotemporal_analysis_of_the_genetic_diversity_of_seal_influenza_A_H10N7_virus_Northwestern_Europe","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":30859474,"first_name":"Ursula","middle_initials":null,"last_name":"Siebert","page_name":"UrsulaSiebert","domain_name":"independent","created_at":"2015-05-07T06:42:56.107-07:00","display_name":"Ursula Siebert","url":"https://independent.academia.edu/UrsulaSiebert"},"attachments":[],"research_interests":[{"id":4206,"name":"Phylogeography","url":"https://www.academia.edu/Documents/in/Phylogeography"},{"id":4233,"name":"Computational Biology","url":"https://www.academia.edu/Documents/in/Computational_Biology"},{"id":8089,"name":"Virology","url":"https://www.academia.edu/Documents/in/Virology"},{"id":28120,"name":"Spatio Temporal Analysis","url":"https://www.academia.edu/Documents/in/Spatio_Temporal_Analysis"},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences"},{"id":54433,"name":"Phylogeny","url":"https://www.academia.edu/Documents/in/Phylogeny"},{"id":75826,"name":"Europe","url":"https://www.academia.edu/Documents/in/Europe"},{"id":577933,"name":"Genetic variation","url":"https://www.academia.edu/Documents/in/Genetic_variation"},{"id":894908,"name":"Amino Acid Substitution Rates","url":"https://www.academia.edu/Documents/in/Amino_Acid_Substitution_Rates"},{"id":985648,"name":"Phoca","url":"https://www.academia.edu/Documents/in/Phoca"},{"id":1742022,"name":"Orthomyxoviridae Infections","url":"https://www.academia.edu/Documents/in/Orthomyxoviridae_Infections"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204066"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204066/Seasonal_distribution_of_harbour_porpoises_and_possible_interference_of_offshore_wind_farms_in_the_German_North_Sea"><img alt="Research paper thumbnail of Seasonal distribution of harbour porpoises and possible interference of offshore wind farms in the German North Sea" class="work-thumbnail" src="https://attachments.academia-assets.com/49655267/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204066/Seasonal_distribution_of_harbour_porpoises_and_possible_interference_of_offshore_wind_farms_in_the_German_North_Sea">Seasonal distribution of harbour porpoises and possible interference of offshore wind farms in the German North Sea</a></div><div class="wp-workCard_item"><span>Marine Ecology Progress Series 383 Pp 295 307</span><span>, 2009</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="2503cbe6265d3b3ee2f8a1517ed983ec" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":49655267,"asset_id":29204066,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/49655267/download_file?st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204066"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204066"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204066; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204066]").text(description); $(".js-view-count[data-work-id=29204066]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204066; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204066']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204066, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "2503cbe6265d3b3ee2f8a1517ed983ec" } } $('.js-work-strip[data-work-id=29204066]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204066,"title":"Seasonal distribution of harbour porpoises and possible interference of offshore wind farms in the German North Sea","translated_title":"","metadata":{"grobid_abstract":"The seasonal distribution of harbour porpoises in the German North Sea was investigated, hot spot areas were identified and the proportion of porpoises potentially affected by the imminent construction of offshore wind farms was estimated. Data were collected during dedicated aerial surveys conducted year-round between 2002 and 2006 following line transect methodology. Survey effort amounted to 44 739 km during which a total of 5121 harbour porpoises was detected, including 258 calves. Our data suggest that porpoises move to distinct areas on a seasonal basis as their biological requirements change. They move into German waters in early spring, reach high numbers in early summer and move out of the area in autumn. The abundance estimates for the German exclusive economic zone and 12 n mile zone were highest in spring (55 048 animals; 95% CI: 32 395 to 101 671) and summer (49 687 animals; 95% CI: 29 009 to 96 385) and lowest in autumn with 15 394 animals (95% CI: 8906 to 29 470). Important aggregation zones were detected in offshore waters: in spring, 2 hot spots, Borkum Reef Ground and Sylt Outer Reef (SOR), were identified as key foraging areas. In summer, only the large hot spot SOR persisted, causing a strong north-south density gradient. In autumn, porpoises were more evenly distributed. Most mother-calf pairs were observed during spring and summer in the SOR, underlining its importance as a foraging area when reproductive costs are high. Spatial overlap exists between important areas for porpoises and areas where offshore wind farms are currently licensed or planned. The proportion of the national stock possibly exposed to the construction noise of 18 licensed wind farms was estimated applying different scenarios. Within a 20 km zone of responsiveness -as worst case scenario -39% of the harbour porpoise stock in the German EEZ could be affected during construction.","publication_date":{"day":null,"month":null,"year":2009,"errors":{}},"publication_name":"Marine Ecology Progress Series 383 Pp 295 307","grobid_abstract_attachment_id":49655267},"translated_abstract":null,"internal_url":"https://www.academia.edu/29204066/Seasonal_distribution_of_harbour_porpoises_and_possible_interference_of_offshore_wind_farms_in_the_German_North_Sea","translated_internal_url":"","created_at":"2016-10-16T22:57:59.958-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":30859474,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":49655267,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/49655267/thumbnails/1.jpg","file_name":"Seasonal_distribution_of_harbour_porpois20161016-14503-h6v9pj.pdf","download_url":"https://www.academia.edu/attachments/49655267/download_file?st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Seasonal_distribution_of_harbour_porpois.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/49655267/Seasonal_distribution_of_harbour_porpois20161016-14503-h6v9pj-libre.pdf?1476684346=\u0026response-content-disposition=attachment%3B+filename%3DSeasonal_distribution_of_harbour_porpois.pdf\u0026Expires=1732725922\u0026Signature=fIGtLOGsFZYh08GjdjYBv6IX2oeNFuJ8jrcaXDygnmgWObZ6AL70gK22cC9dqQnk4gKWCBfvMf9Em5Jgdh7IZ4m5s24HWMTYNrtt7lamDWTsDPGWTJtp~WkfWteEj5MmasTN4yrWaDlZ3Jwm4NQeVlZuWI4UzBudzmBKE~ZG5iVN7JUn51-Sx1MIAAkgR3BdzrpE5js79X9IsOfaISlNR1hUR4vymXDevyKT8~sk7hmK3aXcSewLFcobJloSf03C2LdrW8GGchupB8gXrGIvf5P8fzShYyCUFQZl6lR86fVCEJHnOKslFNBXujkdLmzmc2pPYKCyAob9q74jzbcdfg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Seasonal_distribution_of_harbour_porpoises_and_possible_interference_of_offshore_wind_farms_in_the_German_North_Sea","translated_slug":"","page_count":13,"language":"en","content_type":"Work","owner":{"id":30859474,"first_name":"Ursula","middle_initials":null,"last_name":"Siebert","page_name":"UrsulaSiebert","domain_name":"independent","created_at":"2015-05-07T06:42:56.107-07:00","display_name":"Ursula Siebert","url":"https://independent.academia.edu/UrsulaSiebert"},"attachments":[{"id":49655267,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/49655267/thumbnails/1.jpg","file_name":"Seasonal_distribution_of_harbour_porpois20161016-14503-h6v9pj.pdf","download_url":"https://www.academia.edu/attachments/49655267/download_file?st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Seasonal_distribution_of_harbour_porpois.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/49655267/Seasonal_distribution_of_harbour_porpois20161016-14503-h6v9pj-libre.pdf?1476684346=\u0026response-content-disposition=attachment%3B+filename%3DSeasonal_distribution_of_harbour_porpois.pdf\u0026Expires=1732725922\u0026Signature=fIGtLOGsFZYh08GjdjYBv6IX2oeNFuJ8jrcaXDygnmgWObZ6AL70gK22cC9dqQnk4gKWCBfvMf9Em5Jgdh7IZ4m5s24HWMTYNrtt7lamDWTsDPGWTJtp~WkfWteEj5MmasTN4yrWaDlZ3Jwm4NQeVlZuWI4UzBudzmBKE~ZG5iVN7JUn51-Sx1MIAAkgR3BdzrpE5js79X9IsOfaISlNR1hUR4vymXDevyKT8~sk7hmK3aXcSewLFcobJloSf03C2LdrW8GGchupB8gXrGIvf5P8fzShYyCUFQZl6lR86fVCEJHnOKslFNBXujkdLmzmc2pPYKCyAob9q74jzbcdfg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":173,"name":"Zoology","url":"https://www.academia.edu/Documents/in/Zoology"},{"id":9846,"name":"Ecology","url":"https://www.academia.edu/Documents/in/Ecology"},{"id":57433,"name":"Seasonality","url":"https://www.academia.edu/Documents/in/Seasonality"},{"id":155790,"name":"Aerial Survey","url":"https://www.academia.edu/Documents/in/Aerial_Survey"},{"id":286419,"name":"Density gradient","url":"https://www.academia.edu/Documents/in/Density_gradient"},{"id":342071,"name":"Hot Spot","url":"https://www.academia.edu/Documents/in/Hot_Spot"},{"id":433256,"name":"Wind Farm","url":"https://www.academia.edu/Documents/in/Wind_Farm"},{"id":531422,"name":"North Sea","url":"https://www.academia.edu/Documents/in/North_Sea"},{"id":952246,"name":"Harbour Porpoise","url":"https://www.academia.edu/Documents/in/Harbour_Porpoise"},{"id":1761671,"name":"Exclusive economic zone","url":"https://www.academia.edu/Documents/in/Exclusive_economic_zone"}],"urls":[{"id":7649515,"url":"http://oceanrep.geomar.de/9017/"}]}, dispatcherData: dispatcherData }); 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204062"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204062/Development_of_a_Model_to_Assess_Masking_Potential_for_Marine_Mammals_by_the_Use_of_Air_Guns_in_Antarctic_Waters"><img alt="Research paper thumbnail of Development of a Model to Assess Masking Potential for Marine Mammals by the Use of Air Guns in Antarctic Waters" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204062/Development_of_a_Model_to_Assess_Masking_Potential_for_Marine_Mammals_by_the_Use_of_Air_Guns_in_Antarctic_Waters">Development of a Model to Assess Masking Potential for Marine Mammals by the Use of Air Guns in Antarctic Waters</a></div><div class="wp-workCard_item"><span>Advances in experimental medicine and biology</span><span>, 2016</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">We estimated the long-range effects of air gun array noise on marine mammal communication ranges ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">We estimated the long-range effects of air gun array noise on marine mammal communication ranges in the Southern Ocean. Air gun impulses are subject to significant distortion during propagation, potentially resulting in a quasi-continuous sound. Propagation modeling to estimate the received waveform was conducted. A leaky integrator was used as a hearing model to assess communication masking in three species due to intermittent/continuous air gun sounds. Air gun noise is most probably changing from impulse to continuous noise between 1,000 and 2,000 km from the source, leading to a reduced communication range for, e.g., blue and fin whales up to 2,000 km from the source.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204062"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204062"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204062; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204062]").text(description); $(".js-view-count[data-work-id=29204062]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204062; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204062']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204062, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=29204062]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204062,"title":"Development of a Model to Assess Masking Potential for Marine Mammals by the Use of Air Guns in Antarctic Waters","translated_title":"","metadata":{"abstract":"We estimated the long-range effects of air gun array noise on marine mammal communication ranges in the Southern Ocean. 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The harbour seal population in the North Sea was estimated at 36 000 individuals between 1994 and 1996). However, recurrent Phocine Distemper Virus (PDV) epizooties have affected the North Sea seal population. Recently, 21 500 harbor seals were killed by PDV in the North Sea and adjacent waters in 2002. Some intriguing questions about the interaction between PDV ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204060"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204060"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204060; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204060]").text(description); $(".js-view-count[data-work-id=29204060]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204060; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204060']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204060, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=29204060]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204060,"title":"Mercury, polychlorobiphenyls and stable isotopes in the blood of harbour seals (Phoca vitulina) from the southern North Sea","translated_title":"","metadata":{"abstract":"Abstract:[en] The harbor seal (Phoca vitulina) is one of the most widely distributed seal species and the North Sea contains around 10% of the world population. The harbour seal population in the North Sea was estimated at 36 000 individuals between 1994 and 1996). However, recurrent Phocine Distemper Virus (PDV) epizooties have affected the North Sea seal population. Recently, 21 500 harbor seals were killed by PDV in the North Sea and adjacent waters in 2002. Some intriguing questions about the interaction between PDV ...","publication_date":{"day":null,"month":null,"year":2005,"errors":{}}},"translated_abstract":"Abstract:[en] The harbor seal (Phoca vitulina) is one of the most widely distributed seal species and the North Sea contains around 10% of the world population. The harbour seal population in the North Sea was estimated at 36 000 individuals between 1994 and 1996). However, recurrent Phocine Distemper Virus (PDV) epizooties have affected the North Sea seal population. Recently, 21 500 harbor seals were killed by PDV in the North Sea and adjacent waters in 2002. Some intriguing questions about the interaction between PDV ...","internal_url":"https://www.academia.edu/29204060/Mercury_polychlorobiphenyls_and_stable_isotopes_in_the_blood_of_harbour_seals_Phoca_vitulina_from_the_southern_North_Sea","translated_internal_url":"","created_at":"2016-10-16T22:57:59.407-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":30859474,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Mercury_polychlorobiphenyls_and_stable_isotopes_in_the_blood_of_harbour_seals_Phoca_vitulina_from_the_southern_North_Sea","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":30859474,"first_name":"Ursula","middle_initials":null,"last_name":"Siebert","page_name":"UrsulaSiebert","domain_name":"independent","created_at":"2015-05-07T06:42:56.107-07:00","display_name":"Ursula Siebert","url":"https://independent.academia.edu/UrsulaSiebert"},"attachments":[],"research_interests":[{"id":224144,"name":"Pollutants","url":"https://www.academia.edu/Documents/in/Pollutants"}],"urls":[{"id":7649513,"url":"http://orbi.ulg.ac.be/handle/2268/72901"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204058"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204058/Blood_metal_levels_and_metal_influenced_immune_functions_of_harbour_seals_in_captivity"><img alt="Research paper thumbnail of Blood metal levels and metal-influenced immune functions of harbour seals in captivity" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204058/Blood_metal_levels_and_metal_influenced_immune_functions_of_harbour_seals_in_captivity">Blood metal levels and metal-influenced immune functions of harbour seals in captivity</a></div><div class="wp-workCard_item"><span>Marine Pollution Bulletin 56 Pp 764 769</span><span>, Apr 30, 2008</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Immunological blood parameters and the effects of environmental pollutants on the immune system a...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Immunological blood parameters and the effects of environmental pollutants on the immune system are important to assess the health status of seals. Animals living permanently in seal centres are useful for development and validation of diagnostic tools for free-ranging animals. In this study, parameters of cellular immunity as well as metal concentrations in blood and metal influence on cell proliferation of seven seals from a seal centre were investigated repeatedly using multi-element analysis and a lymphocyte proliferation assay. The metal concentrations, except for tin and chromium, were in general comparable to those of free-ranging animals of the North Sea. The unstimulated and mitogen-stimulated lymphocyte proliferation showed strong intra- and inter-individual variability, which reflected variability in activation of the immune status. Furthermore, both immunosuppressive and stimulative influences of metals on lymphocytes were found. Summarising, the methods used in this investigation provided useful information on these animals, and their application to free-ranging animals can be recommended.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204058"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204058"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204058; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204058]").text(description); $(".js-view-count[data-work-id=29204058]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204058; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204058']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204058, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=29204058]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204058,"title":"Blood metal levels and metal-influenced immune functions of harbour seals in captivity","translated_title":"","metadata":{"abstract":"Immunological blood parameters and the effects of environmental pollutants on the immune system are important to assess the health status of seals. Animals living permanently in seal centres are useful for development and validation of diagnostic tools for free-ranging animals. In this study, parameters of cellular immunity as well as metal concentrations in blood and metal influence on cell proliferation of seven seals from a seal centre were investigated repeatedly using multi-element analysis and a lymphocyte proliferation assay. The metal concentrations, except for tin and chromium, were in general comparable to those of free-ranging animals of the North Sea. The unstimulated and mitogen-stimulated lymphocyte proliferation showed strong intra- and inter-individual variability, which reflected variability in activation of the immune status. Furthermore, both immunosuppressive and stimulative influences of metals on lymphocytes were found. 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The unstimulated and mitogen-stimulated lymphocyte proliferation showed strong intra- and inter-individual variability, which reflected variability in activation of the immune status. Furthermore, both immunosuppressive and stimulative influences of metals on lymphocytes were found. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204054"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204054/Harbour_porpoise_thyroids_Histological_investigations_and_potential_interactions_with_environmental_factors"><img alt="Research paper thumbnail of Harbour porpoise thyroids: Histological investigations and potential interactions with environmental factors" class="work-thumbnail" src="https://attachments.academia-assets.com/49655194/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204054/Harbour_porpoise_thyroids_Histological_investigations_and_potential_interactions_with_environmental_factors">Harbour porpoise thyroids: Histological investigations and potential interactions with environmental factors</a></div><div class="wp-workCard_item"><span>Journal of Wildlife Diseases</span><span>, Oct 1, 2008</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="6f9bd3243864724b3b79159e3e04d87a" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":49655194,"asset_id":29204054,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/49655194/download_file?st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204054"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204054"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204054; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204054]").text(description); $(".js-view-count[data-work-id=29204054]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204054; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204054']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204054, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "6f9bd3243864724b3b79159e3e04d87a" } } $('.js-work-strip[data-work-id=29204054]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204054,"title":"Harbour porpoise thyroids: Histological investigations and potential interactions with environmental factors","translated_title":"","metadata":{"grobid_abstract":"The thyroid plays an important role in development and is of primary importance in metabolism and heat loss for cetaceans, including the harbor porpoise (Phocoena phocoena). Several studies have demonstrated that environmental contaminants can alter various aspects of thyroid function in mammals and may contribute to various histologic changes. The present study completes the data set of a 2006 study by Das et al., by performing histological and immunohistologic investigations on thyroids of 36 harbor porpoises from Belgian and United Kingdom waters. The number and mean diameter of follicles (mm) and the relative proportion of follicular, connective, and vascular tissue (%) were quantified in the thyroid gland of each individual. Interfollicular fibrosis has been observed in these thyroid glands, and the collective findings support the hypothesis of an endocrine disruption of thyroid function through organochlorinated compounds. Our study aimed also to reveal potential relationships between thyroid morphometric data and metal levels (Cd, Fe, Zn, Cu, Se, and Hg) using multivariate statistical analysis. The multiple regressions revealed statistically significant relationships between trace elements (cadmium, selenium, and copper) and thyroid fibrosis. The largely negative relationships are interesting findings but do not support the hypothesis that these elements have an adverse effect on thyroid morphometry. Further research is needed to understand the nature of any relationship between organochlorine and trace element exposure and thyroid gland morphology and function in harbor porpoises.","publication_date":{"day":1,"month":10,"year":2008,"errors":{}},"publication_name":"Journal of Wildlife Diseases","grobid_abstract_attachment_id":49655194},"translated_abstract":null,"internal_url":"https://www.academia.edu/29204054/Harbour_porpoise_thyroids_Histological_investigations_and_potential_interactions_with_environmental_factors","translated_internal_url":"","created_at":"2016-10-16T22:57:58.786-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":30859474,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":49655194,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/49655194/thumbnails/1.jpg","file_name":"Schnitzler_2008_JWD_444_888.pdf","download_url":"https://www.academia.edu/attachments/49655194/download_file?st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Harbour_porpoise_thyroids_Histological_i.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/49655194/Schnitzler_2008_JWD_444_888-libre.pdf?1476684373=\u0026response-content-disposition=attachment%3B+filename%3DHarbour_porpoise_thyroids_Histological_i.pdf\u0026Expires=1732725922\u0026Signature=c6davGsiEvt-OZ9TRSBrveZAwvPl-dugKuZGyU5W3-KrpHHeD3~HGD9l~h6U4HjcJgY7gSjdxjtzB8oNOQIpmHDrWr08RKXvNm4Y02XibU26xXwKibcwfRn9okzRAM5lf1DBgd-r2y609nIY8StigIMQysqPZcBEBohmiqI~LH2N1SuvcFkLn7cNOka2A0edcry~ckv7mPEWoH4zL1skGwn18Ne~fXHlfk8VFCRRrP6ZJSZg5pzBNsbJWsEY7zMfBq53NRAQJhzBx0BosZXnJeLsqtA4E~gbX6HRj0vSo70fiq~064xPdjQL55vBZx86BcaauLnRDenBK68BC6TGOg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Harbour_porpoise_thyroids_Histological_investigations_and_potential_interactions_with_environmental_factors","translated_slug":"","page_count":14,"language":"en","content_type":"Work","owner":{"id":30859474,"first_name":"Ursula","middle_initials":null,"last_name":"Siebert","page_name":"UrsulaSiebert","domain_name":"independent","created_at":"2015-05-07T06:42:56.107-07:00","display_name":"Ursula Siebert","url":"https://independent.academia.edu/UrsulaSiebert"},"attachments":[{"id":49655194,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/49655194/thumbnails/1.jpg","file_name":"Schnitzler_2008_JWD_444_888.pdf","download_url":"https://www.academia.edu/attachments/49655194/download_file?st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Harbour_porpoise_thyroids_Histological_i.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/49655194/Schnitzler_2008_JWD_444_888-libre.pdf?1476684373=\u0026response-content-disposition=attachment%3B+filename%3DHarbour_porpoise_thyroids_Histological_i.pdf\u0026Expires=1732725922\u0026Signature=c6davGsiEvt-OZ9TRSBrveZAwvPl-dugKuZGyU5W3-KrpHHeD3~HGD9l~h6U4HjcJgY7gSjdxjtzB8oNOQIpmHDrWr08RKXvNm4Y02XibU26xXwKibcwfRn9okzRAM5lf1DBgd-r2y609nIY8StigIMQysqPZcBEBohmiqI~LH2N1SuvcFkLn7cNOka2A0edcry~ckv7mPEWoH4zL1skGwn18Ne~fXHlfk8VFCRRrP6ZJSZg5pzBNsbJWsEY7zMfBq53NRAQJhzBx0BosZXnJeLsqtA4E~gbX6HRj0vSo70fiq~064xPdjQL55vBZx86BcaauLnRDenBK68BC6TGOg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":38428,"name":"Wildlife Diseases","url":"https://www.academia.edu/Documents/in/Wildlife_Diseases"}],"urls":[{"id":7649510,"url":"http://orbi.ulg.ac.be/bitstream/2268/992/1/Schnitzler_2008_JWD_44(4)_888.PDF"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204052"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204052/Heavy_metal_and_endocrine_disrupter_impact_on_marine_mammals"><img alt="Research paper thumbnail of Heavy metal and endocrine disrupter impact on marine mammals" class="work-thumbnail" src="https://attachments.academia-assets.com/49655193/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204052/Heavy_metal_and_endocrine_disrupter_impact_on_marine_mammals">Heavy metal and endocrine disrupter impact on marine mammals</a></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="6ec0061015087a35ca355e943ad5dbc4" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":49655193,"asset_id":29204052,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/49655193/download_file?st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204052"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204052"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204052; 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In the North Sea, high levels of mercury, PCBs, methyl sulfonyl PCBs, perfluorinated organochemicals, DDT and toxaphene have been found in the liver and blubber of the harbour porpoise Phocoena phocoena and the harbour seal Phoca vitulina. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204050"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204050/The_influence_of_environmental_and_physiological_factors_on_the_litter_size_of_wild_boar_Sus_scrofa_in_an_agriculture_dominated_area_in_Germany"><img alt="Research paper thumbnail of The influence of environmental and physiological factors on the litter size of wild boar (Sus scrofa) in an agriculture dominated area in Germany" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204050/The_influence_of_environmental_and_physiological_factors_on_the_litter_size_of_wild_boar_Sus_scrofa_in_an_agriculture_dominated_area_in_Germany">The influence of environmental and physiological factors on the litter size of wild boar (Sus scrofa) in an agriculture dominated area in Germany</a></div><div class="wp-workCard_item"><span>The Science of the total environment</span><span>, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The wild boar population has increased enormously in all of Europe over the last decades and caus...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The wild boar population has increased enormously in all of Europe over the last decades and caused problems like crop damage, transmission of diseases, and vehicle accidents. Therefore, it is necessary to investigate the underlying causes of this increase in order to be able to manage populations effectively. The purpose of this study was to analyse how environmental (food and climate) and physiological factors (maternal weight and age) as well as hunting and population density influence the litter size of wild boar populations in Northern Germany. The mean litter size in the studied population for the whole period was 6.6 (range 1–12), which is one of the highest in all of Europe. Litter size was positively influenced by maternal body weight, higher mast yield of oak as well as higher temperature in combination with higher precipitation in summer. Only higher temperature or only higher precipitation in summer however had a negative effect on litter size production. Probably,weathe...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204050"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204050"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204050; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204050]").text(description); $(".js-view-count[data-work-id=29204050]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204050; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204050']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204050, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=29204050]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204050,"title":"The influence of environmental and physiological factors on the litter size of wild boar (Sus scrofa) in an agriculture dominated area in Germany","translated_title":"","metadata":{"abstract":"The wild boar population has increased enormously in all of Europe over the last decades and caused problems like crop damage, transmission of diseases, and vehicle accidents. 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Probably,weathe...","publication_date":{"day":null,"month":null,"year":2015,"errors":{}},"publication_name":"The Science of the total environment"},"translated_abstract":"The wild boar population has increased enormously in all of Europe over the last decades and caused problems like crop damage, transmission of diseases, and vehicle accidents. Therefore, it is necessary to investigate the underlying causes of this increase in order to be able to manage populations effectively. The purpose of this study was to analyse how environmental (food and climate) and physiological factors (maternal weight and age) as well as hunting and population density influence the litter size of wild boar populations in Northern Germany. The mean litter size in the studied population for the whole period was 6.6 (range 1–12), which is one of the highest in all of Europe. Litter size was positively influenced by maternal body weight, higher mast yield of oak as well as higher temperature in combination with higher precipitation in summer. Only higher temperature or only higher precipitation in summer however had a negative effect on litter size production. Probably,weathe...","internal_url":"https://www.academia.edu/29204050/The_influence_of_environmental_and_physiological_factors_on_the_litter_size_of_wild_boar_Sus_scrofa_in_an_agriculture_dominated_area_in_Germany","translated_internal_url":"","created_at":"2016-10-16T22:57:58.452-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":30859474,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"The_influence_of_environmental_and_physiological_factors_on_the_litter_size_of_wild_boar_Sus_scrofa_in_an_agriculture_dominated_area_in_Germany","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":30859474,"first_name":"Ursula","middle_initials":null,"last_name":"Siebert","page_name":"UrsulaSiebert","domain_name":"independent","created_at":"2015-05-07T06:42:56.107-07:00","display_name":"Ursula Siebert","url":"https://independent.academia.edu/UrsulaSiebert"},"attachments":[],"research_interests":[{"id":10225,"name":"Agriculture","url":"https://www.academia.edu/Documents/in/Agriculture"},{"id":11801,"name":"Environmental Monitoring","url":"https://www.academia.edu/Documents/in/Environmental_Monitoring"},{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary"},{"id":50576,"name":"Germany","url":"https://www.academia.edu/Documents/in/Germany"},{"id":162645,"name":"Population Density","url":"https://www.academia.edu/Documents/in/Population_Density"},{"id":419370,"name":"Swine","url":"https://www.academia.edu/Documents/in/Swine"},{"id":993152,"name":"Sus Scrofa","url":"https://www.academia.edu/Documents/in/Sus_Scrofa"},{"id":1971355,"name":"Litter Size","url":"https://www.academia.edu/Documents/in/Litter_Size"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204049"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204049/Xenobiotic_and_Immune_Relevant_Molecular_Biomarkers_in_Harbor_Seals_as_Proxies_for_Pollutant_Burden_and_Effects"><img alt="Research paper thumbnail of Xenobiotic and Immune-Relevant Molecular Biomarkers in Harbor Seals as Proxies for Pollutant Burden and Effects" class="work-thumbnail" src="https://attachments.academia-assets.com/49655263/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204049/Xenobiotic_and_Immune_Relevant_Molecular_Biomarkers_in_Harbor_Seals_as_Proxies_for_Pollutant_Burden_and_Effects">Xenobiotic and Immune-Relevant Molecular Biomarkers in Harbor Seals as Proxies for Pollutant Burden and Effects</a></div><div class="wp-workCard_item"><span>Archives of environmental contamination and toxicology</span><span>, Jan 22, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Harbor seals are exposed to increasing pressure caused by anthropogenic activities in their marin...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Harbor seals are exposed to increasing pressure caused by anthropogenic activities in their marine environment. Persistent organic pollutants (POPs) and trace elements are hazardous contaminants that accumulate in tissues of harbor seals. POPs and trace elements can negatively affect the immune-system and have been reported, e.g., to increase susceptibility to viral infections in seals. Biomarkers of the xenobiotic metabolism, cytokines, and heat-shock protein as cell mediators of the immune-system were established to evaluate the impact of environmental stressors on harbor seals. Harbor seals (n = 54) were captured on sandbanks in the North Sea during 2009-2012. Health assessments, including hematology, were performed, and RNAlater blood samples were taken and analyzed using quantitative polymerase chain reaction. Normalized transcript copy numbers were correlated to hematology and POP concentration in blood and trace metals in blood and fur. A significant correlation between xenob...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="37407e701bfd41c4860f497a35f37a53" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":49655263,"asset_id":29204049,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/49655263/download_file?st=MTczMjcyMjMyMyw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204049"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204049"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204049; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204049]").text(description); $(".js-view-count[data-work-id=29204049]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204049; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204049']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204049, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "37407e701bfd41c4860f497a35f37a53" } } $('.js-work-strip[data-work-id=29204049]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204049,"title":"Xenobiotic and Immune-Relevant Molecular Biomarkers in Harbor Seals as Proxies for Pollutant Burden and Effects","translated_title":"","metadata":{"abstract":"Harbor seals are exposed to increasing pressure caused by anthropogenic activities in their marine environment. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="31221751"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/31221751/The_use_of_an_air_bubble_curtain_to_reduce_the_received_sound_levels_for_harbor_porpoises_Phocoena_phocoena_"><img alt="Research paper thumbnail of The use of an air bubble curtain to reduce the received sound levels for harbor porpoises (Phocoena phocoena)" class="work-thumbnail" src="https://attachments.academia-assets.com/51633654/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/31221751/The_use_of_an_air_bubble_curtain_to_reduce_the_received_sound_levels_for_harbor_porpoises_Phocoena_phocoena_">The use of an air bubble curtain to reduce the received sound levels for harbor porpoises (Phocoena phocoena)</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/UrsulaSiebert">Ursula Siebert</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://lboro.academia.edu/PaulLepper">Paul Lepper</a></span></div><div class="wp-workCard_item"><span>The Journal of the Acoustical Society of America</span><span>, 2011</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">In December 2005 construction work was started to replace a harbor wall in Kerteminde harbor, Den...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">In December 2005 construction work was started to replace a harbor wall in Kerteminde harbor, Denmark. A total of 175 wooden piles were piled into the ground at the waters edge over a period of 3 months. During the same period three harbor porpoises were housed in a marine mammal facility on the opposite side of the harbor. All animals showed strong avoidance reactions after the start of the piling activities. As a measure to reduce the sound exposure for the animals an air bubble curtain was constructed and operated in a direct path between the piling site and the opening of the animals&#x27; semi-natural pool. The sound attenuation effect achieved with this system was determined by quantitative comparison of pile driving impulses simultaneously measured in front of and behind the active air bubble curtain. Mean levels of sound attenuation over a sequence of 95 consecutive pile strikes were 14 dB (standard deviation (s.d.) 3.4 dB) for peak to peak values and 13 dB (s.d. 2.5 dB) for...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="4e4294101f6fa8f157bf6249ebc8fcbc" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":51633654,"asset_id":31221751,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/51633654/download_file?st=MTczMjcyMjMyMyw4LjIyMi4yMDguMTQ2&st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="31221751"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="31221751"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 31221751; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=31221751]").text(description); $(".js-view-count[data-work-id=31221751]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 31221751; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='31221751']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 31221751, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "4e4294101f6fa8f157bf6249ebc8fcbc" } } $('.js-work-strip[data-work-id=31221751]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":31221751,"title":"The use of an air bubble curtain to reduce the received sound levels for harbor porpoises (Phocoena phocoena)","translated_title":"","metadata":{"abstract":"In December 2005 construction work was started to replace a harbor wall in Kerteminde harbor, Denmark. 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class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204078/Phocine_distemper_virus_PDV_seroprevalence_as_predictor_for_future_outbreaks_in_harbour_seals">Phocine distemper virus (PDV) seroprevalence as predictor for future outbreaks in harbour seals</a></div><div class="wp-workCard_item"><span>Veterinary microbiology</span><span>, 2016</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Phocine distemper virus (PDV) infections caused the two most pronounced mass mortalities in marin...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Phocine distemper virus (PDV) infections caused the two most pronounced mass mortalities in marine mammals documented in the past century. During the two outbreaks, 23,000 and 30,000 harbour seals (Phoca vitulina), died in 1988/1989 and 2002 across populations in the Wadden Sea and adjacent waters, respectively. To follow the mechanism and development of disease spreading, the dynamics of Morbillivirus-specific antibodies in harbour seal populations in German and Danish waters were examined. 522 serum samples of free-ranging harbour seals of different ages were sampled between 1990 and 2014. By standard neutralisation assays, Morbillivirus-specific antibodies were detected, using either the PDV isolate 2558/Han 88 or the related canine distemper virus (CDV) strain Onderstepoort. A total of 159 (30.5%) of the harbour seals were seropositive. Annual seroprevalence rates showed an undulating course: Peaks were seen in the post-epidemic years 1990/1991 and 2002/2003. Following each PDV ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204078"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204078"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204078; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204078]").text(description); $(".js-view-count[data-work-id=29204078]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204078; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204078']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204078, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=29204078]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204078,"title":"Phocine distemper virus (PDV) seroprevalence as predictor for future outbreaks in harbour seals","translated_title":"","metadata":{"abstract":"Phocine distemper virus (PDV) infections caused the two most pronounced mass mortalities in marine mammals documented in the past century. During the two outbreaks, 23,000 and 30,000 harbour seals (Phoca vitulina), died in 1988/1989 and 2002 across populations in the Wadden Sea and adjacent waters, respectively. To follow the mechanism and development of disease spreading, the dynamics of Morbillivirus-specific antibodies in harbour seal populations in German and Danish waters were examined. 522 serum samples of free-ranging harbour seals of different ages were sampled between 1990 and 2014. By standard neutralisation assays, Morbillivirus-specific antibodies were detected, using either the PDV isolate 2558/Han 88 or the related canine distemper virus (CDV) strain Onderstepoort. A total of 159 (30.5%) of the harbour seals were seropositive. Annual seroprevalence rates showed an undulating course: Peaks were seen in the post-epidemic years 1990/1991 and 2002/2003. Following each PDV ...","publication_date":{"day":null,"month":null,"year":2016,"errors":{}},"publication_name":"Veterinary microbiology"},"translated_abstract":"Phocine distemper virus (PDV) infections caused the two most pronounced mass mortalities in marine mammals documented in the past century. During the two outbreaks, 23,000 and 30,000 harbour seals (Phoca vitulina), died in 1988/1989 and 2002 across populations in the Wadden Sea and adjacent waters, respectively. To follow the mechanism and development of disease spreading, the dynamics of Morbillivirus-specific antibodies in harbour seal populations in German and Danish waters were examined. 522 serum samples of free-ranging harbour seals of different ages were sampled between 1990 and 2014. By standard neutralisation assays, Morbillivirus-specific antibodies were detected, using either the PDV isolate 2558/Han 88 or the related canine distemper virus (CDV) strain Onderstepoort. A total of 159 (30.5%) of the harbour seals were seropositive. Annual seroprevalence rates showed an undulating course: Peaks were seen in the post-epidemic years 1990/1991 and 2002/2003. Following each PDV ...","internal_url":"https://www.academia.edu/29204078/Phocine_distemper_virus_PDV_seroprevalence_as_predictor_for_future_outbreaks_in_harbour_seals","translated_internal_url":"","created_at":"2016-10-16T22:58:01.510-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":30859474,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Phocine_distemper_virus_PDV_seroprevalence_as_predictor_for_future_outbreaks_in_harbour_seals","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":30859474,"first_name":"Ursula","middle_initials":null,"last_name":"Siebert","page_name":"UrsulaSiebert","domain_name":"independent","created_at":"2015-05-07T06:42:56.107-07:00","display_name":"Ursula Siebert","url":"https://independent.academia.edu/UrsulaSiebert"},"attachments":[],"research_interests":[{"id":159,"name":"Microbiology","url":"https://www.academia.edu/Documents/in/Microbiology"},{"id":3037,"name":"Veterinary Microbiology","url":"https://www.academia.edu/Documents/in/Veterinary_Microbiology"},{"id":644860,"name":"Veterinary Sciences","url":"https://www.academia.edu/Documents/in/Veterinary_Sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204077"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204077/Temporal_and_Spatial_Trends_of_Perfluoroalkylated_Substances_in_Harbour_Porpoise_Phocoena_phocoena_Livers_from_Northern_Europe_1991_2008"><img alt="Research paper thumbnail of Temporal and Spatial Trends of Perfluoroalkylated Substances in Harbour Porpoise (Phocoena phocoena) Livers from Northern Europe, 1991 - 2008" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204077/Temporal_and_Spatial_Trends_of_Perfluoroalkylated_Substances_in_Harbour_Porpoise_Phocoena_phocoena_Livers_from_Northern_Europe_1991_2008">Temporal and Spatial Trends of Perfluoroalkylated Substances in Harbour Porpoise (Phocoena phocoena) Livers from Northern Europe, 1991 - 2008</a></div><div class="wp-workCard_item"><span>Science of the Total Environment</span><span>, Mar 1, 2012</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">ABSTRACT Long-term temporal trends (1991–2008) and spatial differences of perfluoroalkylated subs...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">ABSTRACT Long-term temporal trends (1991–2008) and spatial differences of perfluoroalkylated substances (PFASs) were investigated in harbor porpoise (Phocoena phocoena) liver samples of juvenile females from the Baltic and North Sea. Additionally, spatial differences between the populations in the Baltic Sea and Atlantic Ocean (i.e. Iceland and Norway) and the influence of the body mass, age and sex on the PFAS concentrations were examined. Perfluorooctane sulfonate (PFOS) was the predominant compound with a concentration range of 160–2425 ng/g wet weight (ww), followed by perfluorooctane sulfonamide (PFOSA, 1–237 ng/g ww) and perfluoroundecanoate (PFUnA, 3–124 ng/g ww). In terms of temporal trends, perfluoroalkyl sulfonates (PFSAs) and PFOSA concentrations decreased over time, while, conversely, the C9–C13 perfluoroalkyl carboxylate (PFCA) concentrations increased. Spatial distribution of the contaminant concentrations showed consistently higher concentrations in the Baltic Sea and lowest concentrations in the Icelandic population of the Atlantic Ocean.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204077"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204077"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204077; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204077]").text(description); $(".js-view-count[data-work-id=29204077]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204077; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204077']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204077, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=29204077]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204077,"title":"Temporal and Spatial Trends of Perfluoroalkylated Substances in Harbour Porpoise (Phocoena phocoena) Livers from Northern Europe, 1991 - 2008","translated_title":"","metadata":{"abstract":"ABSTRACT Long-term temporal trends (1991–2008) and spatial differences of perfluoroalkylated substances (PFASs) were investigated in harbor porpoise (Phocoena phocoena) liver samples of juvenile females from the Baltic and North Sea. Additionally, spatial differences between the populations in the Baltic Sea and Atlantic Ocean (i.e. Iceland and Norway) and the influence of the body mass, age and sex on the PFAS concentrations were examined. Perfluorooctane sulfonate (PFOS) was the predominant compound with a concentration range of 160–2425 ng/g wet weight (ww), followed by perfluorooctane sulfonamide (PFOSA, 1–237 ng/g ww) and perfluoroundecanoate (PFUnA, 3–124 ng/g ww). In terms of temporal trends, perfluoroalkyl sulfonates (PFSAs) and PFOSA concentrations decreased over time, while, conversely, the C9–C13 perfluoroalkyl carboxylate (PFCA) concentrations increased. Spatial distribution of the contaminant concentrations showed consistently higher concentrations in the Baltic Sea and lowest concentrations in the Icelandic population of the Atlantic Ocean.","publication_date":{"day":1,"month":3,"year":2012,"errors":{}},"publication_name":"Science of the Total Environment"},"translated_abstract":"ABSTRACT Long-term temporal trends (1991–2008) and spatial differences of perfluoroalkylated substances (PFASs) were investigated in harbor porpoise (Phocoena phocoena) liver samples of juvenile females from the Baltic and North Sea. Additionally, spatial differences between the populations in the Baltic Sea and Atlantic Ocean (i.e. Iceland and Norway) and the influence of the body mass, age and sex on the PFAS concentrations were examined. Perfluorooctane sulfonate (PFOS) was the predominant compound with a concentration range of 160–2425 ng/g wet weight (ww), followed by perfluorooctane sulfonamide (PFOSA, 1–237 ng/g ww) and perfluoroundecanoate (PFUnA, 3–124 ng/g ww). In terms of temporal trends, perfluoroalkyl sulfonates (PFSAs) and PFOSA concentrations decreased over time, while, conversely, the C9–C13 perfluoroalkyl carboxylate (PFCA) concentrations increased. Spatial distribution of the contaminant concentrations showed consistently higher concentrations in the Baltic Sea and lowest concentrations in the Icelandic population of the Atlantic Ocean.","internal_url":"https://www.academia.edu/29204077/Temporal_and_Spatial_Trends_of_Perfluoroalkylated_Substances_in_Harbour_Porpoise_Phocoena_phocoena_Livers_from_Northern_Europe_1991_2008","translated_internal_url":"","created_at":"2016-10-16T22:58:01.371-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":30859474,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Temporal_and_Spatial_Trends_of_Perfluoroalkylated_Substances_in_Harbour_Porpoise_Phocoena_phocoena_Livers_from_Northern_Europe_1991_2008","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":30859474,"first_name":"Ursula","middle_initials":null,"last_name":"Siebert","page_name":"UrsulaSiebert","domain_name":"independent","created_at":"2015-05-07T06:42:56.107-07:00","display_name":"Ursula Siebert","url":"https://independent.academia.edu/UrsulaSiebert"},"attachments":[],"research_interests":[{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204076"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204076/Emerging_and_recurring_diseases_in_cetaceans_worldwide_and_the_role_of_environmental_stressors"><img alt="Research paper thumbnail of Emerging and recurring diseases in cetaceans worldwide and the role of environmental stressors" class="work-thumbnail" src="https://attachments.academia-assets.com/49655270/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204076/Emerging_and_recurring_diseases_in_cetaceans_worldwide_and_the_role_of_environmental_stressors">Emerging and recurring diseases in cetaceans worldwide and the role of environmental stressors</a></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="faa69ccaafee9390b9aa65ab028e0e59" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":49655270,"asset_id":29204076,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/49655270/download_file?st=MTczMjcyMjMyMyw4LjIyMi4yMDguMTQ2&st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204076"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204076"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204076; 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Cetacean morbilliviruses and papillomaviruses as well as Brucella spp. and Toxoplasma gondii are thought to interfere with population abundance by inducing high mortalities, lowering reproductive success or by synergistically increasing the virulence of other diseases. Severe cases of lobomycosis and lobomycosis-like disease (LLD) may contribute to the death of some dolphins. The zoonotic hazard of marine mammal brucellosis and toxoplasmosis may have been underestimated, attributable to frequent misdiagnoses and underreporting, particularly in developing countries and remote areas where carcass handling without protective gear and human consumption of fresh cetacean products are commonplace. Environmental factors seem to play a role in the emergence and pathogenicity of morbillivirus epidemics, lobomycosis/LLD, toxoplasmosis, poxvirus-associated tattoo skin disease and, in harbour porpoises, infectious diseases of multifactorial aetiology. Inshore and estuarine cetaceans incur higher risks than pelagic cetaceans due to habitats often severely altered by anthropogenic factors such as chemical and biological contamination, direct and indirect fisheries interactions, traumatic injuries from vessel collisions and climate change.","publication_date":{"day":1,"month":6,"year":2008,"errors":{}},"grobid_abstract_attachment_id":49655270},"translated_abstract":null,"internal_url":"https://www.academia.edu/29204076/Emerging_and_recurring_diseases_in_cetaceans_worldwide_and_the_role_of_environmental_stressors","translated_internal_url":"","created_at":"2016-10-16T22:58:01.221-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":30859474,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":49655270,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/49655270/thumbnails/1.jpg","file_name":"Emerging_and_recurring_diseases_in_cetac20161016-6506-1txy4fq.pdf","download_url":"https://www.academia.edu/attachments/49655270/download_file?st=MTczMjcyMjMyMyw4LjIyMi4yMDguMTQ2&st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Emerging_and_recurring_diseases_in_cetac.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/49655270/Emerging_and_recurring_diseases_in_cetac20161016-6506-1txy4fq-libre.pdf?1476684347=\u0026response-content-disposition=attachment%3B+filename%3DEmerging_and_recurring_diseases_in_cetac.pdf\u0026Expires=1732725922\u0026Signature=TKspWbGXJgF3dD0gKOpeNkxHkZDfMjKAzPUmXSBAsJCBXvjMsDC-sxBMVZN10Hwoq5Fa0PF0iJJ47yYXtEgGxTU67u71zjH2xLETFBsBgIZZYetjmnU7HnhYPMBuqnxY2uZYe1xJmUmSLABTuVcE00S8js80YjiK3tZwHuri1EoPf3V2d6fqtVqjqw8npLrdEm9OCelpfXkLQFZzZDcgFwMh8uN9miux114vCYvbeqZUQ8OaSz96tXA8-7~otTFxTICwZ3wFuEq6LUP7Ko1sj~zLMxriI97XGZMlWX-pGUOLP9dyyKxaOHKn6pBgL352zV38fBdjl8eZ~XCfwe94Cg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Emerging_and_recurring_diseases_in_cetaceans_worldwide_and_the_role_of_environmental_stressors","translated_slug":"","page_count":15,"language":"en","content_type":"Work","owner":{"id":30859474,"first_name":"Ursula","middle_initials":null,"last_name":"Siebert","page_name":"UrsulaSiebert","domain_name":"independent","created_at":"2015-05-07T06:42:56.107-07:00","display_name":"Ursula Siebert","url":"https://independent.academia.edu/UrsulaSiebert"},"attachments":[{"id":49655270,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/49655270/thumbnails/1.jpg","file_name":"Emerging_and_recurring_diseases_in_cetac20161016-6506-1txy4fq.pdf","download_url":"https://www.academia.edu/attachments/49655270/download_file?st=MTczMjcyMjMyMyw4LjIyMi4yMDguMTQ2&st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Emerging_and_recurring_diseases_in_cetac.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/49655270/Emerging_and_recurring_diseases_in_cetac20161016-6506-1txy4fq-libre.pdf?1476684347=\u0026response-content-disposition=attachment%3B+filename%3DEmerging_and_recurring_diseases_in_cetac.pdf\u0026Expires=1732725922\u0026Signature=TKspWbGXJgF3dD0gKOpeNkxHkZDfMjKAzPUmXSBAsJCBXvjMsDC-sxBMVZN10Hwoq5Fa0PF0iJJ47yYXtEgGxTU67u71zjH2xLETFBsBgIZZYetjmnU7HnhYPMBuqnxY2uZYe1xJmUmSLABTuVcE00S8js80YjiK3tZwHuri1EoPf3V2d6fqtVqjqw8npLrdEm9OCelpfXkLQFZzZDcgFwMh8uN9miux114vCYvbeqZUQ8OaSz96tXA8-7~otTFxTICwZ3wFuEq6LUP7Ko1sj~zLMxriI97XGZMlWX-pGUOLP9dyyKxaOHKn6pBgL352zV38fBdjl8eZ~XCfwe94Cg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[],"urls":[]}, dispatcherData: dispatcherData }); 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The interaction between toxicological results (Zn, Cd, Cu, Fe, Se, Hg), stable isotope data (δ 13 C and δ 15 N) and the most common pathological findings, namely emaciation and lesions of the respiratory system, were investigated in 132 porpoises collected along the coasts of northern France, Belgium, Germany, Denmark, Iceland and Norway between 1994 and 2001. The body condition of harbour porpoises stranded on the French, Belgian and German coasts was poor compared to that of by-catch individuals from Iceland and Norway, as reflected by blubber thickness and hepatic to total body-mass ratio. High Zn and Hg concentrations were observed in some porpoises collected along the southern North Sea coast compared to by-catch individuals from Iceland, Norway and the Baltic Sea. Increasing Zn levels were observed with deteriorating health condition (emaciation and bronchopneumonia), while Hg increases were not significant. The increases were not related to shrinking liver mass which remained unchanged. These observations indicate a general redistribution of trace metals within the organs (muscles and blubber to liver), as a result of protein and lipid catabolism. Muscle δ 13 C and δ 15 N values remained unchanged with deteriorating body condition. Cd concentrations were associated only with age and low δ 15 N values, indicating that high Cd concentrations in Iceland and Norway porpoises may be partly diet-related, i.e. a result of Cd contaminated prey.","publication_date":{"day":null,"month":null,"year":2005,"errors":{}},"grobid_abstract_attachment_id":49655266},"translated_abstract":null,"internal_url":"https://www.academia.edu/29204075/Ecological_and_pathological_factors_related_to_trace_metal_concentrations_in_harbour_seal_Phoca_vitulina_in_the_North_Sea","translated_internal_url":"","created_at":"2016-10-16T22:58:01.026-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":30859474,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":49655266,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/49655266/thumbnails/1.jpg","file_name":"Ecological_and_pathological_factors_rela20161016-20451-cfkez8.pdf","download_url":"https://www.academia.edu/attachments/49655266/download_file?st=MTczMjcyMjMyMyw4LjIyMi4yMDguMTQ2&st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Ecological_and_pathological_factors_rela.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/49655266/Ecological_and_pathological_factors_rela20161016-20451-cfkez8-libre.pdf?1476684348=\u0026response-content-disposition=attachment%3B+filename%3DEcological_and_pathological_factors_rela.pdf\u0026Expires=1732725922\u0026Signature=TiNTb7Hyk3Zad4e55LmApmXQFOfuyBzlfmaOMn6TEsv958WIRhAhcO7YKj2EFYL8wPJNn~jN9uXVHglkyuohwrcELJkgXeZAgRj2OuJN2FJT037zgXmjhaiTp5JE6bXdFPrUhNBGu2gCIuLCNlhS4Rlv1iClcIDqgomHbE35MK7pP1JkRo0NBNWfNjT2KcyNsCgpEUsopj1o1ZdR2Tf1RSxR8x29fzggsKbOg1WxmYWySG1sWcHQm2juFu9yONnKG4iXrbGJg96btOSyvZ-z8DfsPrCMgQ9wNBjC1coelDmblTlexhz~3JtPzkoDqRCuRq1Aa~PXCFijn~ft2E3Nog__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Ecological_and_pathological_factors_related_to_trace_metal_concentrations_in_harbour_seal_Phoca_vitulina_in_the_North_Sea","translated_slug":"","page_count":13,"language":"en","content_type":"Work","owner":{"id":30859474,"first_name":"Ursula","middle_initials":null,"last_name":"Siebert","page_name":"UrsulaSiebert","domain_name":"independent","created_at":"2015-05-07T06:42:56.107-07:00","display_name":"Ursula Siebert","url":"https://independent.academia.edu/UrsulaSiebert"},"attachments":[{"id":49655266,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/49655266/thumbnails/1.jpg","file_name":"Ecological_and_pathological_factors_rela20161016-20451-cfkez8.pdf","download_url":"https://www.academia.edu/attachments/49655266/download_file?st=MTczMjcyMjMyMyw4LjIyMi4yMDguMTQ2&st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Ecological_and_pathological_factors_rela.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/49655266/Ecological_and_pathological_factors_rela20161016-20451-cfkez8-libre.pdf?1476684348=\u0026response-content-disposition=attachment%3B+filename%3DEcological_and_pathological_factors_rela.pdf\u0026Expires=1732725922\u0026Signature=TiNTb7Hyk3Zad4e55LmApmXQFOfuyBzlfmaOMn6TEsv958WIRhAhcO7YKj2EFYL8wPJNn~jN9uXVHglkyuohwrcELJkgXeZAgRj2OuJN2FJT037zgXmjhaiTp5JE6bXdFPrUhNBGu2gCIuLCNlhS4Rlv1iClcIDqgomHbE35MK7pP1JkRo0NBNWfNjT2KcyNsCgpEUsopj1o1ZdR2Tf1RSxR8x29fzggsKbOg1WxmYWySG1sWcHQm2juFu9yONnKG4iXrbGJg96btOSyvZ-z8DfsPrCMgQ9wNBjC1coelDmblTlexhz~3JtPzkoDqRCuRq1Aa~PXCFijn~ft2E3Nog__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":173,"name":"Zoology","url":"https://www.academia.edu/Documents/in/Zoology"},{"id":9846,"name":"Ecology","url":"https://www.academia.edu/Documents/in/Ecology"},{"id":224144,"name":"Pollutants","url":"https://www.academia.edu/Documents/in/Pollutants"}],"urls":[{"id":7649521,"url":"http://orbi.ulg.ac.be/handle/2268/72654"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204074"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204074/Seals_at_sea_%C3%A2_modelling_seal_distribution_in_the_German_Bight_based_on_aerial_survey_data"><img alt="Research paper thumbnail of Seals at sea â�� modelling seal distribution in the German Bight based on aerial survey data" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204074/Seals_at_sea_%C3%A2_modelling_seal_distribution_in_the_German_Bight_based_on_aerial_survey_data">Seals at sea â�� modelling seal distribution in the German Bight based on aerial survey data</a></div><div class="wp-workCard_item"><span>Marine Biology 156 Pp 811 820</span><span>, 2009</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204074"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204074"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204074; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204073"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204073/Isocyamus_delphinii_First_record_of_whale_lice_on_a_harbour_porpoise_Phocoena_phocoena_from_German_waters"><img alt="Research paper thumbnail of Isocyamus delphinii: First record of whale-lice on a harbour porpoise (Phocoena phocoena) from German waters" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204073/Isocyamus_delphinii_First_record_of_whale_lice_on_a_harbour_porpoise_Phocoena_phocoena_from_German_waters">Isocyamus delphinii: First record of whale-lice on a harbour porpoise (Phocoena phocoena) from German waters</a></div><div class="wp-workCard_item"><span>Veterinary Record 161 Pp 526 528</span><span>, 2007</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204073"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204073"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204073; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204073]").text(description); $(".js-view-count[data-work-id=29204073]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204073; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204073']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204073, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204071"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204071/Viral_protein_expression_and_phenotyping_of_inflammatory_responses_in_the_central_nervous_system_of_phocine_distemper_virus_infected_harbor_seals_Phoca_vitulina_"><img alt="Research paper thumbnail of Viral protein expression and phenotyping of inflammatory responses in the central nervous system of phocine distemper virus-infected harbor seals ( Phoca vitulina)" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204071/Viral_protein_expression_and_phenotyping_of_inflammatory_responses_in_the_central_nervous_system_of_phocine_distemper_virus_infected_harbor_seals_Phoca_vitulina_">Viral protein expression and phenotyping of inflammatory responses in the central nervous system of phocine distemper virus-infected harbor seals ( Phoca vitulina)</a></div><div class="wp-workCard_item"><span>Veterinary Microbiology</span><span>, Mar 1, 2010</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The central nervous system (CNS) represents an important target organ of the phocine distemper vi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The central nervous system (CNS) represents an important target organ of the phocine distemper virus (PDV). The aim of the present study was to characterize pathological changes in the CNS of harbor seals suffering from natural PDV-infection. The distribution of virus protein and mRNA was investigated by immunohistochemistry (IHC) and in situ hybridization, respectively. In addition, inflammatory and glial cells were characterized by IHC. Polioencephalitis with glial activation, neuronal death and perivascular mononuclear infiltrations in the cerebral cortex was the main histopathological finding. Inflammatory responses, dominated by CD3(+) T-cells and activated microglia/macrophages were associated with a prominent MHC-II upregulation within the CNS. Viral protein was found predominantly in neurofilament-expressing neurons within inflamed areas as demonstrated by immunohistochemical double-labeling. Morbillivirus nucleo-, phospho-, matrix-, fusion- and hemagglutinin-proteins were found in CNS-lesions. The expressions of viral matrix- and fusion-proteins were reduced in severely inflamed plaques. Comparison of viral protein and mRNA expression revealed a diminished amount of viral phosphoprotein preferentially associated with perivascular inflammation. In summary, CNS-lesions in PDV-infected seals are similar to canine distemper virus-induced acute polioencephalitis in dogs and measles virus inclusion body polioencephalitis in men, respectively.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204071"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204071"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204071; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204071]").text(description); $(".js-view-count[data-work-id=29204071]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204071; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204071']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204071, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=29204071]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204071,"title":"Viral protein expression and phenotyping of inflammatory responses in the central nervous system of phocine distemper virus-infected harbor seals ( Phoca vitulina)","translated_title":"","metadata":{"abstract":"The central nervous system (CNS) represents an important target organ of the phocine distemper virus (PDV). The aim of the present study was to characterize pathological changes in the CNS of harbor seals suffering from natural PDV-infection. The distribution of virus protein and mRNA was investigated by immunohistochemistry (IHC) and in situ hybridization, respectively. In addition, inflammatory and glial cells were characterized by IHC. Polioencephalitis with glial activation, neuronal death and perivascular mononuclear infiltrations in the cerebral cortex was the main histopathological finding. Inflammatory responses, dominated by CD3(+) T-cells and activated microglia/macrophages were associated with a prominent MHC-II upregulation within the CNS. Viral protein was found predominantly in neurofilament-expressing neurons within inflamed areas as demonstrated by immunohistochemical double-labeling. Morbillivirus nucleo-, phospho-, matrix-, fusion- and hemagglutinin-proteins were found in CNS-lesions. The expressions of viral matrix- and fusion-proteins were reduced in severely inflamed plaques. Comparison of viral protein and mRNA expression revealed a diminished amount of viral phosphoprotein preferentially associated with perivascular inflammation. In summary, CNS-lesions in PDV-infected seals are similar to canine distemper virus-induced acute polioencephalitis in dogs and measles virus inclusion body polioencephalitis in men, respectively.","publication_date":{"day":1,"month":3,"year":2010,"errors":{}},"publication_name":"Veterinary Microbiology"},"translated_abstract":"The central nervous system (CNS) represents an important target organ of the phocine distemper virus (PDV). The aim of the present study was to characterize pathological changes in the CNS of harbor seals suffering from natural PDV-infection. The distribution of virus protein and mRNA was investigated by immunohistochemistry (IHC) and in situ hybridization, respectively. In addition, inflammatory and glial cells were characterized by IHC. Polioencephalitis with glial activation, neuronal death and perivascular mononuclear infiltrations in the cerebral cortex was the main histopathological finding. Inflammatory responses, dominated by CD3(+) T-cells and activated microglia/macrophages were associated with a prominent MHC-II upregulation within the CNS. Viral protein was found predominantly in neurofilament-expressing neurons within inflamed areas as demonstrated by immunohistochemical double-labeling. Morbillivirus nucleo-, phospho-, matrix-, fusion- and hemagglutinin-proteins were found in CNS-lesions. The expressions of viral matrix- and fusion-proteins were reduced in severely inflamed plaques. Comparison of viral protein and mRNA expression revealed a diminished amount of viral phosphoprotein preferentially associated with perivascular inflammation. In summary, CNS-lesions in PDV-infected seals are similar to canine distemper virus-induced acute polioencephalitis in dogs and measles virus inclusion body polioencephalitis in men, respectively.","internal_url":"https://www.academia.edu/29204071/Viral_protein_expression_and_phenotyping_of_inflammatory_responses_in_the_central_nervous_system_of_phocine_distemper_virus_infected_harbor_seals_Phoca_vitulina_","translated_internal_url":"","created_at":"2016-10-16T22:58:00.412-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":30859474,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Viral_protein_expression_and_phenotyping_of_inflammatory_responses_in_the_central_nervous_system_of_phocine_distemper_virus_infected_harbor_seals_Phoca_vitulina_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":30859474,"first_name":"Ursula","middle_initials":null,"last_name":"Siebert","page_name":"UrsulaSiebert","domain_name":"independent","created_at":"2015-05-07T06:42:56.107-07:00","display_name":"Ursula Siebert","url":"https://independent.academia.edu/UrsulaSiebert"},"attachments":[],"research_interests":[{"id":159,"name":"Microbiology","url":"https://www.academia.edu/Documents/in/Microbiology"},{"id":3037,"name":"Veterinary Microbiology","url":"https://www.academia.edu/Documents/in/Veterinary_Microbiology"},{"id":12071,"name":"Immunohistochemistry","url":"https://www.academia.edu/Documents/in/Immunohistochemistry"},{"id":35414,"name":"Veterinary","url":"https://www.academia.edu/Documents/in/Veterinary"},{"id":37836,"name":"In Situ Hybridization","url":"https://www.academia.edu/Documents/in/In_Situ_Hybridization"},{"id":39977,"name":"Measles Virus","url":"https://www.academia.edu/Documents/in/Measles_Virus"},{"id":78467,"name":"Cerebral Cortex","url":"https://www.academia.edu/Documents/in/Cerebral_Cortex"},{"id":130117,"name":"Glial Cell","url":"https://www.academia.edu/Documents/in/Glial_Cell"},{"id":147195,"name":"Central Nervous System","url":"https://www.academia.edu/Documents/in/Central_Nervous_System"},{"id":213897,"name":"Phenotype","url":"https://www.academia.edu/Documents/in/Phenotype"},{"id":284067,"name":"Inclusion Bodies","url":"https://www.academia.edu/Documents/in/Inclusion_Bodies"},{"id":310960,"name":"mRna expression levels","url":"https://www.academia.edu/Documents/in/mRna_expression_levels"},{"id":394656,"name":"Phocine Distemper Virus","url":"https://www.academia.edu/Documents/in/Phocine_Distemper_Virus"},{"id":396278,"name":"Neuronal Death","url":"https://www.academia.edu/Documents/in/Neuronal_Death"},{"id":501806,"name":"Protein Expression","url":"https://www.academia.edu/Documents/in/Protein_Expression"},{"id":644860,"name":"Veterinary Sciences","url":"https://www.academia.edu/Documents/in/Veterinary_Sciences"},{"id":746733,"name":"Phoca Vitulina","url":"https://www.academia.edu/Documents/in/Phoca_Vitulina"},{"id":900875,"name":"Canine Distemper Virus","url":"https://www.academia.edu/Documents/in/Canine_Distemper_Virus"},{"id":985648,"name":"Phoca","url":"https://www.academia.edu/Documents/in/Phoca"},{"id":1109079,"name":"Encephalitis","url":"https://www.academia.edu/Documents/in/Encephalitis"},{"id":1159037,"name":"Fusion Protein","url":"https://www.academia.edu/Documents/in/Fusion_Protein"},{"id":2159933,"name":"Distemper","url":"https://www.academia.edu/Documents/in/Distemper"},{"id":2454817,"name":"Inflammatory response","url":"https://www.academia.edu/Documents/in/Inflammatory_response"}],"urls":[{"id":7649517,"url":"http://cat.inist.fr/?aModele=afficheN\u0026cpsidt=23264887"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204068"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204068/Spatiotemporal_analysis_of_the_genetic_diversity_of_seal_influenza_A_H10N7_virus_Northwestern_Europe"><img alt="Research paper thumbnail of Spatiotemporal analysis of the genetic diversity of seal influenza A(H10N7) virus, Northwestern Europe" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204068/Spatiotemporal_analysis_of_the_genetic_diversity_of_seal_influenza_A_H10N7_virus_Northwestern_Europe">Spatiotemporal analysis of the genetic diversity of seal influenza A(H10N7) virus, Northwestern Europe</a></div><div class="wp-workCard_item"><span>Journal of Virology</span><span>, 2016</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Influenza A viruses are major pathogens for humans, domestic animals and wildlife that cross the ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Influenza A viruses are major pathogens for humans, domestic animals and wildlife that cross the species barrier occasionally. In spring 2014, increased mortality of harbor seals (Phoca vitulina) was reported in Sweden and Denmark, associated with infection with an influenza A(H10N7) virus. Within a few months, this virus spread to seals of the coastal waters of Germany and the Netherlands, causing the death of thousands of animals. Genetic analysis of the hemagglutinin (HA) and neuraminidase (NA) genes of this seal influenza A(H10N7) virus revealed that it was most closely related to various avian influenza A(H10N7) viruses. The collection of samples from infected seals during the course of the outbreak provided an unique opportunity to follow the adaptation of this avian virus to its new seal host. Sequence data was obtained from samples collected from 41 different seals from four different countries between April 2014 and January 2015 using Sanger sequencing and next-generation sequencing to describe the molecular epidemiology of the seal influenza A(H10N7) virus. The majority of sequence variation occurred in the HA gene, and some mutations corresponded with amino acid changes not found in H10 viruses isolated from Eurasian birds. Also, sequence variation in the HA gene was greater at the beginning than at the end of the epidemic, when a number of the mutations observed earlier had been fixed. These results imply that when an avian influenza virus jumps the species barrier from birds to seals, amino acid changes in the HA may occur rapidly and are important for virus adaptation to its new mammalian host. Influenza A viruses are major pathogens for humans, domestic animals and wildlife. In addition to the continuous circulation of influenza A viruses among various host species, cross-species transmission of influenza A viruses occurs occasionally. Wild waterfowl and shorebirds are the main reservoir for most influenza A virus subtypes, and spillover of influenza A viruses from birds to humans or other mammalian species may result in major outbreaks. In the present study, various sequencing methods were used to elucidate the genetic changes that occurred after the introduction and subsequent spread of an avian influenza A(H10N7) among harbor seals of Northwestern Europe using various samples collected during the outbreak. Such detailed knowledge of genetic changes necessary for introduction and adaptation of avian influenza A viruses to mammalian hosts is important for a rapid risk assessment of such viruses soon after they cross the species barrier.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204068"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204068"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204068; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204068]").text(description); $(".js-view-count[data-work-id=29204068]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204068; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204068']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204068, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=29204068]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204068,"title":"Spatiotemporal analysis of the genetic diversity of seal influenza A(H10N7) virus, Northwestern Europe","translated_title":"","metadata":{"abstract":"Influenza A viruses are major pathogens for humans, domestic animals and wildlife that cross the species barrier occasionally. In spring 2014, increased mortality of harbor seals (Phoca vitulina) was reported in Sweden and Denmark, associated with infection with an influenza A(H10N7) virus. Within a few months, this virus spread to seals of the coastal waters of Germany and the Netherlands, causing the death of thousands of animals. Genetic analysis of the hemagglutinin (HA) and neuraminidase (NA) genes of this seal influenza A(H10N7) virus revealed that it was most closely related to various avian influenza A(H10N7) viruses. The collection of samples from infected seals during the course of the outbreak provided an unique opportunity to follow the adaptation of this avian virus to its new seal host. Sequence data was obtained from samples collected from 41 different seals from four different countries between April 2014 and January 2015 using Sanger sequencing and next-generation sequencing to describe the molecular epidemiology of the seal influenza A(H10N7) virus. The majority of sequence variation occurred in the HA gene, and some mutations corresponded with amino acid changes not found in H10 viruses isolated from Eurasian birds. Also, sequence variation in the HA gene was greater at the beginning than at the end of the epidemic, when a number of the mutations observed earlier had been fixed. These results imply that when an avian influenza virus jumps the species barrier from birds to seals, amino acid changes in the HA may occur rapidly and are important for virus adaptation to its new mammalian host. Influenza A viruses are major pathogens for humans, domestic animals and wildlife. In addition to the continuous circulation of influenza A viruses among various host species, cross-species transmission of influenza A viruses occurs occasionally. Wild waterfowl and shorebirds are the main reservoir for most influenza A virus subtypes, and spillover of influenza A viruses from birds to humans or other mammalian species may result in major outbreaks. In the present study, various sequencing methods were used to elucidate the genetic changes that occurred after the introduction and subsequent spread of an avian influenza A(H10N7) among harbor seals of Northwestern Europe using various samples collected during the outbreak. Such detailed knowledge of genetic changes necessary for introduction and adaptation of avian influenza A viruses to mammalian hosts is important for a rapid risk assessment of such viruses soon after they cross the species barrier.","publication_date":{"day":null,"month":null,"year":2016,"errors":{}},"publication_name":"Journal of Virology"},"translated_abstract":"Influenza A viruses are major pathogens for humans, domestic animals and wildlife that cross the species barrier occasionally. In spring 2014, increased mortality of harbor seals (Phoca vitulina) was reported in Sweden and Denmark, associated with infection with an influenza A(H10N7) virus. Within a few months, this virus spread to seals of the coastal waters of Germany and the Netherlands, causing the death of thousands of animals. Genetic analysis of the hemagglutinin (HA) and neuraminidase (NA) genes of this seal influenza A(H10N7) virus revealed that it was most closely related to various avian influenza A(H10N7) viruses. The collection of samples from infected seals during the course of the outbreak provided an unique opportunity to follow the adaptation of this avian virus to its new seal host. Sequence data was obtained from samples collected from 41 different seals from four different countries between April 2014 and January 2015 using Sanger sequencing and next-generation sequencing to describe the molecular epidemiology of the seal influenza A(H10N7) virus. The majority of sequence variation occurred in the HA gene, and some mutations corresponded with amino acid changes not found in H10 viruses isolated from Eurasian birds. Also, sequence variation in the HA gene was greater at the beginning than at the end of the epidemic, when a number of the mutations observed earlier had been fixed. These results imply that when an avian influenza virus jumps the species barrier from birds to seals, amino acid changes in the HA may occur rapidly and are important for virus adaptation to its new mammalian host. Influenza A viruses are major pathogens for humans, domestic animals and wildlife. In addition to the continuous circulation of influenza A viruses among various host species, cross-species transmission of influenza A viruses occurs occasionally. Wild waterfowl and shorebirds are the main reservoir for most influenza A virus subtypes, and spillover of influenza A viruses from birds to humans or other mammalian species may result in major outbreaks. In the present study, various sequencing methods were used to elucidate the genetic changes that occurred after the introduction and subsequent spread of an avian influenza A(H10N7) among harbor seals of Northwestern Europe using various samples collected during the outbreak. Such detailed knowledge of genetic changes necessary for introduction and adaptation of avian influenza A viruses to mammalian hosts is important for a rapid risk assessment of such viruses soon after they cross the species barrier.","internal_url":"https://www.academia.edu/29204068/Spatiotemporal_analysis_of_the_genetic_diversity_of_seal_influenza_A_H10N7_virus_Northwestern_Europe","translated_internal_url":"","created_at":"2016-10-16T22:58:00.169-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":30859474,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Spatiotemporal_analysis_of_the_genetic_diversity_of_seal_influenza_A_H10N7_virus_Northwestern_Europe","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":30859474,"first_name":"Ursula","middle_initials":null,"last_name":"Siebert","page_name":"UrsulaSiebert","domain_name":"independent","created_at":"2015-05-07T06:42:56.107-07:00","display_name":"Ursula Siebert","url":"https://independent.academia.edu/UrsulaSiebert"},"attachments":[],"research_interests":[{"id":4206,"name":"Phylogeography","url":"https://www.academia.edu/Documents/in/Phylogeography"},{"id":4233,"name":"Computational Biology","url":"https://www.academia.edu/Documents/in/Computational_Biology"},{"id":8089,"name":"Virology","url":"https://www.academia.edu/Documents/in/Virology"},{"id":28120,"name":"Spatio Temporal Analysis","url":"https://www.academia.edu/Documents/in/Spatio_Temporal_Analysis"},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences"},{"id":54433,"name":"Phylogeny","url":"https://www.academia.edu/Documents/in/Phylogeny"},{"id":75826,"name":"Europe","url":"https://www.academia.edu/Documents/in/Europe"},{"id":577933,"name":"Genetic variation","url":"https://www.academia.edu/Documents/in/Genetic_variation"},{"id":894908,"name":"Amino Acid Substitution Rates","url":"https://www.academia.edu/Documents/in/Amino_Acid_Substitution_Rates"},{"id":985648,"name":"Phoca","url":"https://www.academia.edu/Documents/in/Phoca"},{"id":1742022,"name":"Orthomyxoviridae Infections","url":"https://www.academia.edu/Documents/in/Orthomyxoviridae_Infections"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204066"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204066/Seasonal_distribution_of_harbour_porpoises_and_possible_interference_of_offshore_wind_farms_in_the_German_North_Sea"><img alt="Research paper thumbnail of Seasonal distribution of harbour porpoises and possible interference of offshore wind farms in the German North Sea" class="work-thumbnail" src="https://attachments.academia-assets.com/49655267/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204066/Seasonal_distribution_of_harbour_porpoises_and_possible_interference_of_offshore_wind_farms_in_the_German_North_Sea">Seasonal distribution of harbour porpoises and possible interference of offshore wind farms in the German North Sea</a></div><div class="wp-workCard_item"><span>Marine Ecology Progress Series 383 Pp 295 307</span><span>, 2009</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="2503cbe6265d3b3ee2f8a1517ed983ec" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":49655267,"asset_id":29204066,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/49655267/download_file?st=MTczMjcyMjMyMyw4LjIyMi4yMDguMTQ2&st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204066"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204066"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204066; 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Data were collected during dedicated aerial surveys conducted year-round between 2002 and 2006 following line transect methodology. Survey effort amounted to 44 739 km during which a total of 5121 harbour porpoises was detected, including 258 calves. Our data suggest that porpoises move to distinct areas on a seasonal basis as their biological requirements change. They move into German waters in early spring, reach high numbers in early summer and move out of the area in autumn. The abundance estimates for the German exclusive economic zone and 12 n mile zone were highest in spring (55 048 animals; 95% CI: 32 395 to 101 671) and summer (49 687 animals; 95% CI: 29 009 to 96 385) and lowest in autumn with 15 394 animals (95% CI: 8906 to 29 470). Important aggregation zones were detected in offshore waters: in spring, 2 hot spots, Borkum Reef Ground and Sylt Outer Reef (SOR), were identified as key foraging areas. In summer, only the large hot spot SOR persisted, causing a strong north-south density gradient. In autumn, porpoises were more evenly distributed. Most mother-calf pairs were observed during spring and summer in the SOR, underlining its importance as a foraging area when reproductive costs are high. Spatial overlap exists between important areas for porpoises and areas where offshore wind farms are currently licensed or planned. The proportion of the national stock possibly exposed to the construction noise of 18 licensed wind farms was estimated applying different scenarios. Within a 20 km zone of responsiveness -as worst case scenario -39% of the harbour porpoise stock in the German EEZ could be affected during construction.","publication_date":{"day":null,"month":null,"year":2009,"errors":{}},"publication_name":"Marine Ecology Progress Series 383 Pp 295 307","grobid_abstract_attachment_id":49655267},"translated_abstract":null,"internal_url":"https://www.academia.edu/29204066/Seasonal_distribution_of_harbour_porpoises_and_possible_interference_of_offshore_wind_farms_in_the_German_North_Sea","translated_internal_url":"","created_at":"2016-10-16T22:57:59.958-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":30859474,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":49655267,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/49655267/thumbnails/1.jpg","file_name":"Seasonal_distribution_of_harbour_porpois20161016-14503-h6v9pj.pdf","download_url":"https://www.academia.edu/attachments/49655267/download_file?st=MTczMjcyMjMyMyw4LjIyMi4yMDguMTQ2&st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Seasonal_distribution_of_harbour_porpois.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/49655267/Seasonal_distribution_of_harbour_porpois20161016-14503-h6v9pj-libre.pdf?1476684346=\u0026response-content-disposition=attachment%3B+filename%3DSeasonal_distribution_of_harbour_porpois.pdf\u0026Expires=1732725922\u0026Signature=fIGtLOGsFZYh08GjdjYBv6IX2oeNFuJ8jrcaXDygnmgWObZ6AL70gK22cC9dqQnk4gKWCBfvMf9Em5Jgdh7IZ4m5s24HWMTYNrtt7lamDWTsDPGWTJtp~WkfWteEj5MmasTN4yrWaDlZ3Jwm4NQeVlZuWI4UzBudzmBKE~ZG5iVN7JUn51-Sx1MIAAkgR3BdzrpE5js79X9IsOfaISlNR1hUR4vymXDevyKT8~sk7hmK3aXcSewLFcobJloSf03C2LdrW8GGchupB8gXrGIvf5P8fzShYyCUFQZl6lR86fVCEJHnOKslFNBXujkdLmzmc2pPYKCyAob9q74jzbcdfg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Seasonal_distribution_of_harbour_porpoises_and_possible_interference_of_offshore_wind_farms_in_the_German_North_Sea","translated_slug":"","page_count":13,"language":"en","content_type":"Work","owner":{"id":30859474,"first_name":"Ursula","middle_initials":null,"last_name":"Siebert","page_name":"UrsulaSiebert","domain_name":"independent","created_at":"2015-05-07T06:42:56.107-07:00","display_name":"Ursula Siebert","url":"https://independent.academia.edu/UrsulaSiebert"},"attachments":[{"id":49655267,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/49655267/thumbnails/1.jpg","file_name":"Seasonal_distribution_of_harbour_porpois20161016-14503-h6v9pj.pdf","download_url":"https://www.academia.edu/attachments/49655267/download_file?st=MTczMjcyMjMyMyw4LjIyMi4yMDguMTQ2&st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Seasonal_distribution_of_harbour_porpois.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/49655267/Seasonal_distribution_of_harbour_porpois20161016-14503-h6v9pj-libre.pdf?1476684346=\u0026response-content-disposition=attachment%3B+filename%3DSeasonal_distribution_of_harbour_porpois.pdf\u0026Expires=1732725922\u0026Signature=fIGtLOGsFZYh08GjdjYBv6IX2oeNFuJ8jrcaXDygnmgWObZ6AL70gK22cC9dqQnk4gKWCBfvMf9Em5Jgdh7IZ4m5s24HWMTYNrtt7lamDWTsDPGWTJtp~WkfWteEj5MmasTN4yrWaDlZ3Jwm4NQeVlZuWI4UzBudzmBKE~ZG5iVN7JUn51-Sx1MIAAkgR3BdzrpE5js79X9IsOfaISlNR1hUR4vymXDevyKT8~sk7hmK3aXcSewLFcobJloSf03C2LdrW8GGchupB8gXrGIvf5P8fzShYyCUFQZl6lR86fVCEJHnOKslFNBXujkdLmzmc2pPYKCyAob9q74jzbcdfg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":173,"name":"Zoology","url":"https://www.academia.edu/Documents/in/Zoology"},{"id":9846,"name":"Ecology","url":"https://www.academia.edu/Documents/in/Ecology"},{"id":57433,"name":"Seasonality","url":"https://www.academia.edu/Documents/in/Seasonality"},{"id":155790,"name":"Aerial Survey","url":"https://www.academia.edu/Documents/in/Aerial_Survey"},{"id":286419,"name":"Density gradient","url":"https://www.academia.edu/Documents/in/Density_gradient"},{"id":342071,"name":"Hot Spot","url":"https://www.academia.edu/Documents/in/Hot_Spot"},{"id":433256,"name":"Wind Farm","url":"https://www.academia.edu/Documents/in/Wind_Farm"},{"id":531422,"name":"North Sea","url":"https://www.academia.edu/Documents/in/North_Sea"},{"id":952246,"name":"Harbour Porpoise","url":"https://www.academia.edu/Documents/in/Harbour_Porpoise"},{"id":1761671,"name":"Exclusive economic zone","url":"https://www.academia.edu/Documents/in/Exclusive_economic_zone"}],"urls":[{"id":7649515,"url":"http://oceanrep.geomar.de/9017/"}]}, dispatcherData: dispatcherData }); 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204062"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204062/Development_of_a_Model_to_Assess_Masking_Potential_for_Marine_Mammals_by_the_Use_of_Air_Guns_in_Antarctic_Waters"><img alt="Research paper thumbnail of Development of a Model to Assess Masking Potential for Marine Mammals by the Use of Air Guns in Antarctic Waters" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204062/Development_of_a_Model_to_Assess_Masking_Potential_for_Marine_Mammals_by_the_Use_of_Air_Guns_in_Antarctic_Waters">Development of a Model to Assess Masking Potential for Marine Mammals by the Use of Air Guns in Antarctic Waters</a></div><div class="wp-workCard_item"><span>Advances in experimental medicine and biology</span><span>, 2016</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">We estimated the long-range effects of air gun array noise on marine mammal communication ranges ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">We estimated the long-range effects of air gun array noise on marine mammal communication ranges in the Southern Ocean. Air gun impulses are subject to significant distortion during propagation, potentially resulting in a quasi-continuous sound. Propagation modeling to estimate the received waveform was conducted. A leaky integrator was used as a hearing model to assess communication masking in three species due to intermittent/continuous air gun sounds. Air gun noise is most probably changing from impulse to continuous noise between 1,000 and 2,000 km from the source, leading to a reduced communication range for, e.g., blue and fin whales up to 2,000 km from the source.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204062"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204062"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204062; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204062]").text(description); $(".js-view-count[data-work-id=29204062]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204062; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204062']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204062, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=29204062]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204062,"title":"Development of a Model to Assess Masking Potential for Marine Mammals by the Use of Air Guns in Antarctic Waters","translated_title":"","metadata":{"abstract":"We estimated the long-range effects of air gun array noise on marine mammal communication ranges in the Southern Ocean. 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The harbour seal population in the North Sea was estimated at 36 000 individuals between 1994 and 1996). However, recurrent Phocine Distemper Virus (PDV) epizooties have affected the North Sea seal population. Recently, 21 500 harbor seals were killed by PDV in the North Sea and adjacent waters in 2002. Some intriguing questions about the interaction between PDV ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204060"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204060"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204060; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204060]").text(description); $(".js-view-count[data-work-id=29204060]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204060; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204060']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204060, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=29204060]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204060,"title":"Mercury, polychlorobiphenyls and stable isotopes in the blood of harbour seals (Phoca vitulina) from the southern North Sea","translated_title":"","metadata":{"abstract":"Abstract:[en] The harbor seal (Phoca vitulina) is one of the most widely distributed seal species and the North Sea contains around 10% of the world population. The harbour seal population in the North Sea was estimated at 36 000 individuals between 1994 and 1996). However, recurrent Phocine Distemper Virus (PDV) epizooties have affected the North Sea seal population. Recently, 21 500 harbor seals were killed by PDV in the North Sea and adjacent waters in 2002. Some intriguing questions about the interaction between PDV ...","publication_date":{"day":null,"month":null,"year":2005,"errors":{}}},"translated_abstract":"Abstract:[en] The harbor seal (Phoca vitulina) is one of the most widely distributed seal species and the North Sea contains around 10% of the world population. The harbour seal population in the North Sea was estimated at 36 000 individuals between 1994 and 1996). However, recurrent Phocine Distemper Virus (PDV) epizooties have affected the North Sea seal population. Recently, 21 500 harbor seals were killed by PDV in the North Sea and adjacent waters in 2002. Some intriguing questions about the interaction between PDV ...","internal_url":"https://www.academia.edu/29204060/Mercury_polychlorobiphenyls_and_stable_isotopes_in_the_blood_of_harbour_seals_Phoca_vitulina_from_the_southern_North_Sea","translated_internal_url":"","created_at":"2016-10-16T22:57:59.407-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":30859474,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Mercury_polychlorobiphenyls_and_stable_isotopes_in_the_blood_of_harbour_seals_Phoca_vitulina_from_the_southern_North_Sea","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":30859474,"first_name":"Ursula","middle_initials":null,"last_name":"Siebert","page_name":"UrsulaSiebert","domain_name":"independent","created_at":"2015-05-07T06:42:56.107-07:00","display_name":"Ursula Siebert","url":"https://independent.academia.edu/UrsulaSiebert"},"attachments":[],"research_interests":[{"id":224144,"name":"Pollutants","url":"https://www.academia.edu/Documents/in/Pollutants"}],"urls":[{"id":7649513,"url":"http://orbi.ulg.ac.be/handle/2268/72901"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204058"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204058/Blood_metal_levels_and_metal_influenced_immune_functions_of_harbour_seals_in_captivity"><img alt="Research paper thumbnail of Blood metal levels and metal-influenced immune functions of harbour seals in captivity" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204058/Blood_metal_levels_and_metal_influenced_immune_functions_of_harbour_seals_in_captivity">Blood metal levels and metal-influenced immune functions of harbour seals in captivity</a></div><div class="wp-workCard_item"><span>Marine Pollution Bulletin 56 Pp 764 769</span><span>, Apr 30, 2008</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Immunological blood parameters and the effects of environmental pollutants on the immune system a...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Immunological blood parameters and the effects of environmental pollutants on the immune system are important to assess the health status of seals. Animals living permanently in seal centres are useful for development and validation of diagnostic tools for free-ranging animals. In this study, parameters of cellular immunity as well as metal concentrations in blood and metal influence on cell proliferation of seven seals from a seal centre were investigated repeatedly using multi-element analysis and a lymphocyte proliferation assay. The metal concentrations, except for tin and chromium, were in general comparable to those of free-ranging animals of the North Sea. The unstimulated and mitogen-stimulated lymphocyte proliferation showed strong intra- and inter-individual variability, which reflected variability in activation of the immune status. Furthermore, both immunosuppressive and stimulative influences of metals on lymphocytes were found. Summarising, the methods used in this investigation provided useful information on these animals, and their application to free-ranging animals can be recommended.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204058"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204058"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204058; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204058]").text(description); $(".js-view-count[data-work-id=29204058]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204058; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204058']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204058, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=29204058]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204058,"title":"Blood metal levels and metal-influenced immune functions of harbour seals in captivity","translated_title":"","metadata":{"abstract":"Immunological blood parameters and the effects of environmental pollutants on the immune system are important to assess the health status of seals. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204054"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204054/Harbour_porpoise_thyroids_Histological_investigations_and_potential_interactions_with_environmental_factors"><img alt="Research paper thumbnail of Harbour porpoise thyroids: Histological investigations and potential interactions with environmental factors" class="work-thumbnail" src="https://attachments.academia-assets.com/49655194/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204054/Harbour_porpoise_thyroids_Histological_investigations_and_potential_interactions_with_environmental_factors">Harbour porpoise thyroids: Histological investigations and potential interactions with environmental factors</a></div><div class="wp-workCard_item"><span>Journal of Wildlife Diseases</span><span>, Oct 1, 2008</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="6f9bd3243864724b3b79159e3e04d87a" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":49655194,"asset_id":29204054,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/49655194/download_file?st=MTczMjcyMjMyMyw4LjIyMi4yMDguMTQ2&st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204054"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204054"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204054; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204054]").text(description); $(".js-view-count[data-work-id=29204054]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204054; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204054']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204054, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "6f9bd3243864724b3b79159e3e04d87a" } } $('.js-work-strip[data-work-id=29204054]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204054,"title":"Harbour porpoise thyroids: Histological investigations and potential interactions with environmental factors","translated_title":"","metadata":{"grobid_abstract":"The thyroid plays an important role in development and is of primary importance in metabolism and heat loss for cetaceans, including the harbor porpoise (Phocoena phocoena). Several studies have demonstrated that environmental contaminants can alter various aspects of thyroid function in mammals and may contribute to various histologic changes. The present study completes the data set of a 2006 study by Das et al., by performing histological and immunohistologic investigations on thyroids of 36 harbor porpoises from Belgian and United Kingdom waters. The number and mean diameter of follicles (mm) and the relative proportion of follicular, connective, and vascular tissue (%) were quantified in the thyroid gland of each individual. Interfollicular fibrosis has been observed in these thyroid glands, and the collective findings support the hypothesis of an endocrine disruption of thyroid function through organochlorinated compounds. Our study aimed also to reveal potential relationships between thyroid morphometric data and metal levels (Cd, Fe, Zn, Cu, Se, and Hg) using multivariate statistical analysis. The multiple regressions revealed statistically significant relationships between trace elements (cadmium, selenium, and copper) and thyroid fibrosis. The largely negative relationships are interesting findings but do not support the hypothesis that these elements have an adverse effect on thyroid morphometry. Further research is needed to understand the nature of any relationship between organochlorine and trace element exposure and thyroid gland morphology and function in harbor porpoises.","publication_date":{"day":1,"month":10,"year":2008,"errors":{}},"publication_name":"Journal of Wildlife Diseases","grobid_abstract_attachment_id":49655194},"translated_abstract":null,"internal_url":"https://www.academia.edu/29204054/Harbour_porpoise_thyroids_Histological_investigations_and_potential_interactions_with_environmental_factors","translated_internal_url":"","created_at":"2016-10-16T22:57:58.786-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":30859474,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":49655194,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/49655194/thumbnails/1.jpg","file_name":"Schnitzler_2008_JWD_444_888.pdf","download_url":"https://www.academia.edu/attachments/49655194/download_file?st=MTczMjcyMjMyMyw4LjIyMi4yMDguMTQ2&st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Harbour_porpoise_thyroids_Histological_i.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/49655194/Schnitzler_2008_JWD_444_888-libre.pdf?1476684373=\u0026response-content-disposition=attachment%3B+filename%3DHarbour_porpoise_thyroids_Histological_i.pdf\u0026Expires=1732725922\u0026Signature=c6davGsiEvt-OZ9TRSBrveZAwvPl-dugKuZGyU5W3-KrpHHeD3~HGD9l~h6U4HjcJgY7gSjdxjtzB8oNOQIpmHDrWr08RKXvNm4Y02XibU26xXwKibcwfRn9okzRAM5lf1DBgd-r2y609nIY8StigIMQysqPZcBEBohmiqI~LH2N1SuvcFkLn7cNOka2A0edcry~ckv7mPEWoH4zL1skGwn18Ne~fXHlfk8VFCRRrP6ZJSZg5pzBNsbJWsEY7zMfBq53NRAQJhzBx0BosZXnJeLsqtA4E~gbX6HRj0vSo70fiq~064xPdjQL55vBZx86BcaauLnRDenBK68BC6TGOg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Harbour_porpoise_thyroids_Histological_investigations_and_potential_interactions_with_environmental_factors","translated_slug":"","page_count":14,"language":"en","content_type":"Work","owner":{"id":30859474,"first_name":"Ursula","middle_initials":null,"last_name":"Siebert","page_name":"UrsulaSiebert","domain_name":"independent","created_at":"2015-05-07T06:42:56.107-07:00","display_name":"Ursula Siebert","url":"https://independent.academia.edu/UrsulaSiebert"},"attachments":[{"id":49655194,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/49655194/thumbnails/1.jpg","file_name":"Schnitzler_2008_JWD_444_888.pdf","download_url":"https://www.academia.edu/attachments/49655194/download_file?st=MTczMjcyMjMyMyw4LjIyMi4yMDguMTQ2&st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Harbour_porpoise_thyroids_Histological_i.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/49655194/Schnitzler_2008_JWD_444_888-libre.pdf?1476684373=\u0026response-content-disposition=attachment%3B+filename%3DHarbour_porpoise_thyroids_Histological_i.pdf\u0026Expires=1732725922\u0026Signature=c6davGsiEvt-OZ9TRSBrveZAwvPl-dugKuZGyU5W3-KrpHHeD3~HGD9l~h6U4HjcJgY7gSjdxjtzB8oNOQIpmHDrWr08RKXvNm4Y02XibU26xXwKibcwfRn9okzRAM5lf1DBgd-r2y609nIY8StigIMQysqPZcBEBohmiqI~LH2N1SuvcFkLn7cNOka2A0edcry~ckv7mPEWoH4zL1skGwn18Ne~fXHlfk8VFCRRrP6ZJSZg5pzBNsbJWsEY7zMfBq53NRAQJhzBx0BosZXnJeLsqtA4E~gbX6HRj0vSo70fiq~064xPdjQL55vBZx86BcaauLnRDenBK68BC6TGOg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":38428,"name":"Wildlife Diseases","url":"https://www.academia.edu/Documents/in/Wildlife_Diseases"}],"urls":[{"id":7649510,"url":"http://orbi.ulg.ac.be/bitstream/2268/992/1/Schnitzler_2008_JWD_44(4)_888.PDF"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204052"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204052/Heavy_metal_and_endocrine_disrupter_impact_on_marine_mammals"><img alt="Research paper thumbnail of Heavy metal and endocrine disrupter impact on marine mammals" class="work-thumbnail" src="https://attachments.academia-assets.com/49655193/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204052/Heavy_metal_and_endocrine_disrupter_impact_on_marine_mammals">Heavy metal and endocrine disrupter impact on marine mammals</a></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="6ec0061015087a35ca355e943ad5dbc4" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":49655193,"asset_id":29204052,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/49655193/download_file?st=MTczMjcyMjMyMyw4LjIyMi4yMDguMTQ2&st=MTczMjcyMjMyMiw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204052"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204052"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204052; 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In the North Sea, high levels of mercury, PCBs, methyl sulfonyl PCBs, perfluorinated organochemicals, DDT and toxaphene have been found in the liver and blubber of the harbour porpoise Phocoena phocoena and the harbour seal Phoca vitulina. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204050"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204050/The_influence_of_environmental_and_physiological_factors_on_the_litter_size_of_wild_boar_Sus_scrofa_in_an_agriculture_dominated_area_in_Germany"><img alt="Research paper thumbnail of The influence of environmental and physiological factors on the litter size of wild boar (Sus scrofa) in an agriculture dominated area in Germany" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204050/The_influence_of_environmental_and_physiological_factors_on_the_litter_size_of_wild_boar_Sus_scrofa_in_an_agriculture_dominated_area_in_Germany">The influence of environmental and physiological factors on the litter size of wild boar (Sus scrofa) in an agriculture dominated area in Germany</a></div><div class="wp-workCard_item"><span>The Science of the total environment</span><span>, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The wild boar population has increased enormously in all of Europe over the last decades and caus...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The wild boar population has increased enormously in all of Europe over the last decades and caused problems like crop damage, transmission of diseases, and vehicle accidents. Therefore, it is necessary to investigate the underlying causes of this increase in order to be able to manage populations effectively. The purpose of this study was to analyse how environmental (food and climate) and physiological factors (maternal weight and age) as well as hunting and population density influence the litter size of wild boar populations in Northern Germany. The mean litter size in the studied population for the whole period was 6.6 (range 1–12), which is one of the highest in all of Europe. Litter size was positively influenced by maternal body weight, higher mast yield of oak as well as higher temperature in combination with higher precipitation in summer. Only higher temperature or only higher precipitation in summer however had a negative effect on litter size production. Probably,weathe...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204050"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204050"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204050; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204050]").text(description); $(".js-view-count[data-work-id=29204050]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204050; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204050']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204050, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=29204050]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204050,"title":"The influence of environmental and physiological factors on the litter size of wild boar (Sus scrofa) in an agriculture dominated area in Germany","translated_title":"","metadata":{"abstract":"The wild boar population has increased enormously in all of Europe over the last decades and caused problems like crop damage, transmission of diseases, and vehicle accidents. 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Probably,weathe...","publication_date":{"day":null,"month":null,"year":2015,"errors":{}},"publication_name":"The Science of the total environment"},"translated_abstract":"The wild boar population has increased enormously in all of Europe over the last decades and caused problems like crop damage, transmission of diseases, and vehicle accidents. Therefore, it is necessary to investigate the underlying causes of this increase in order to be able to manage populations effectively. The purpose of this study was to analyse how environmental (food and climate) and physiological factors (maternal weight and age) as well as hunting and population density influence the litter size of wild boar populations in Northern Germany. The mean litter size in the studied population for the whole period was 6.6 (range 1–12), which is one of the highest in all of Europe. Litter size was positively influenced by maternal body weight, higher mast yield of oak as well as higher temperature in combination with higher precipitation in summer. Only higher temperature or only higher precipitation in summer however had a negative effect on litter size production. Probably,weathe...","internal_url":"https://www.academia.edu/29204050/The_influence_of_environmental_and_physiological_factors_on_the_litter_size_of_wild_boar_Sus_scrofa_in_an_agriculture_dominated_area_in_Germany","translated_internal_url":"","created_at":"2016-10-16T22:57:58.452-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":30859474,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"The_influence_of_environmental_and_physiological_factors_on_the_litter_size_of_wild_boar_Sus_scrofa_in_an_agriculture_dominated_area_in_Germany","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":30859474,"first_name":"Ursula","middle_initials":null,"last_name":"Siebert","page_name":"UrsulaSiebert","domain_name":"independent","created_at":"2015-05-07T06:42:56.107-07:00","display_name":"Ursula Siebert","url":"https://independent.academia.edu/UrsulaSiebert"},"attachments":[],"research_interests":[{"id":10225,"name":"Agriculture","url":"https://www.academia.edu/Documents/in/Agriculture"},{"id":11801,"name":"Environmental Monitoring","url":"https://www.academia.edu/Documents/in/Environmental_Monitoring"},{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary"},{"id":50576,"name":"Germany","url":"https://www.academia.edu/Documents/in/Germany"},{"id":162645,"name":"Population Density","url":"https://www.academia.edu/Documents/in/Population_Density"},{"id":419370,"name":"Swine","url":"https://www.academia.edu/Documents/in/Swine"},{"id":993152,"name":"Sus Scrofa","url":"https://www.academia.edu/Documents/in/Sus_Scrofa"},{"id":1971355,"name":"Litter Size","url":"https://www.academia.edu/Documents/in/Litter_Size"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29204049"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29204049/Xenobiotic_and_Immune_Relevant_Molecular_Biomarkers_in_Harbor_Seals_as_Proxies_for_Pollutant_Burden_and_Effects"><img alt="Research paper thumbnail of Xenobiotic and Immune-Relevant Molecular Biomarkers in Harbor Seals as Proxies for Pollutant Burden and Effects" class="work-thumbnail" src="https://attachments.academia-assets.com/49655263/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29204049/Xenobiotic_and_Immune_Relevant_Molecular_Biomarkers_in_Harbor_Seals_as_Proxies_for_Pollutant_Burden_and_Effects">Xenobiotic and Immune-Relevant Molecular Biomarkers in Harbor Seals as Proxies for Pollutant Burden and Effects</a></div><div class="wp-workCard_item"><span>Archives of environmental contamination and toxicology</span><span>, Jan 22, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Harbor seals are exposed to increasing pressure caused by anthropogenic activities in their marin...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Harbor seals are exposed to increasing pressure caused by anthropogenic activities in their marine environment. Persistent organic pollutants (POPs) and trace elements are hazardous contaminants that accumulate in tissues of harbor seals. POPs and trace elements can negatively affect the immune-system and have been reported, e.g., to increase susceptibility to viral infections in seals. Biomarkers of the xenobiotic metabolism, cytokines, and heat-shock protein as cell mediators of the immune-system were established to evaluate the impact of environmental stressors on harbor seals. Harbor seals (n = 54) were captured on sandbanks in the North Sea during 2009-2012. Health assessments, including hematology, were performed, and RNAlater blood samples were taken and analyzed using quantitative polymerase chain reaction. Normalized transcript copy numbers were correlated to hematology and POP concentration in blood and trace metals in blood and fur. A significant correlation between xenob...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="37407e701bfd41c4860f497a35f37a53" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":49655263,"asset_id":29204049,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/49655263/download_file?st=MTczMjcyMjMyMyw4LjIyMi4yMDguMTQ2&st=MTczMjcyMjMyMyw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29204049"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29204049"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29204049; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29204049]").text(description); $(".js-view-count[data-work-id=29204049]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29204049; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29204049']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29204049, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "37407e701bfd41c4860f497a35f37a53" } } $('.js-work-strip[data-work-id=29204049]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29204049,"title":"Xenobiotic and Immune-Relevant Molecular Biomarkers in Harbor Seals as Proxies for Pollutant Burden and Effects","translated_title":"","metadata":{"abstract":"Harbor seals are exposed to increasing pressure caused by anthropogenic activities in their marine environment. 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A significant correlation between xenob...","publication_date":{"day":22,"month":1,"year":2015,"errors":{}},"publication_name":"Archives of environmental contamination and toxicology"},"translated_abstract":"Harbor seals are exposed to increasing pressure caused by anthropogenic activities in their marine environment. Persistent organic pollutants (POPs) and trace elements are hazardous contaminants that accumulate in tissues of harbor seals. POPs and trace elements can negatively affect the immune-system and have been reported, e.g., to increase susceptibility to viral infections in seals. Biomarkers of the xenobiotic metabolism, cytokines, and heat-shock protein as cell mediators of the immune-system were established to evaluate the impact of environmental stressors on harbor seals. Harbor seals (n = 54) were captured on sandbanks in the North Sea during 2009-2012. Health assessments, including hematology, were performed, and RNAlater blood samples were taken and analyzed using quantitative polymerase chain reaction. Normalized transcript copy numbers were correlated to hematology and POP concentration in blood and trace metals in blood and fur. 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