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bachtiarica Bunge</title> <meta name="description" content="Search results for: Satureja bachtiarica Bunge"> <meta name="keywords" content="Satureja bachtiarica Bunge"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Satureja bachtiarica Bunge"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 17</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Satureja bachtiarica Bunge</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17</span> Satureja bachtiarica Bunge Induce Apoptosis via Mitochondrial Intrinsic Pathway and G1 Cell Cycle Arrest</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hamed%20Karimian">Hamed Karimian</a>, <a href="https://publications.waset.org/abstracts/search?q=Noraziah%20Nordin"> Noraziah Nordin</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamad%20Ibrahim%20Noordin"> Mohamad Ibrahim Noordin</a>, <a href="https://publications.waset.org/abstracts/search?q=Syam%20Mohan"> Syam Mohan</a>, <a href="https://publications.waset.org/abstracts/search?q=Mahboubeh%20Razavi"> Mahboubeh Razavi</a>, <a href="https://publications.waset.org/abstracts/search?q=Najihah%20Mohd%20Hashim"> Najihah Mohd Hashim</a>, <a href="https://publications.waset.org/abstracts/search?q=Happipah%20Mohd%20Ali"> Happipah Mohd Ali</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Satureja bachtiarica Bunge is a perennial medicinal plant belonging to the Lamiaceae family and endemic species in Iran. Satureja bachtiarica Bunge with the local name of Marzeh koohi is edible vegetable use as flavoring agent, anti-bacterial and to relieve cough and indigestion. In this study, the anti-cancer effect of Satureja bachtiarica Bunge on the MDA-MB-231 cell line as an Breast cancer cell model has been analyzed for the first time. Satureja bachtiarica Bunge was extracted using different solvents in the order of increasing polarity. Cytotoxicity activity of hexane extract of Satureja bachtiarica Bunge (SBHE) was observed using MTT assay. Acridine orange/Propidium iodide staining was used to detect early apoptosis; Annexin-V-FITC assay was carried out to observe the detection of cell-surface Phosphatidylserine (PS), with Annexin-Vserving as a marker for apoptotic cells. Caspase 3/7, 8 and-9 assays showed significantly activation of caspase-9 where lead intrinsic mitochondrial pathway. Bcl-2/Bax expressions and cell cycle arrest were also investigated. SBHE had exhibited significantly higher cytotoxicity against MDA-MB-231 Cell line compare to other cell lines. A significant increase in chromatin condensation in the cell nucleus was observed by fluorescence analysis. Treatment of MDA-MB-231 cells with SBHE encouraged apoptosis, by down-regulating Bcl-2 and up-regulating Bax, which lead the activation of caspase 9. Moreover, SBHE treatment significantly arrested MDA-MB-231 cells in the G1 phase. Together, the results presented in this study demonstrated that SBHE inhibited the proliferation of MDA-MB-231 cells, leading cell cycle arrest and programmed cell death, which was confirmed to be through the mitochondrial pathway. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Satureja%20bachtiarica%20Bunge" title="Satureja bachtiarica Bunge">Satureja bachtiarica Bunge</a>, <a href="https://publications.waset.org/abstracts/search?q=MDA-MB-231" title=" MDA-MB-231"> MDA-MB-231</a>, <a href="https://publications.waset.org/abstracts/search?q=apoptosis" title=" apoptosis"> apoptosis</a>, <a href="https://publications.waset.org/abstracts/search?q=annexin-V" title=" annexin-V"> annexin-V</a>, <a href="https://publications.waset.org/abstracts/search?q=cell%20cycle" title=" cell cycle"> cell cycle</a> </p> <a href="https://publications.waset.org/abstracts/13586/satureja-bachtiarica-bunge-induce-apoptosis-via-mitochondrial-intrinsic-pathway-and-g1-cell-cycle-arrest" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/13586.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">337</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">16</span> Rapid Biosynthesis of Silver-Montmorillonite Nanocomposite Using Water Extract of Satureja hortensis L. and Evaluation of the Antibacterial Capacities</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sajjad%20Sedaghat">Sajjad Sedaghat</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this work, facile and green biosynthesis and characterization of silver–montmorillonite (MMT) nanocomposite is reported at room temperature. Silver nanoparticles (Ag–NPs) were synthesized into the interlamellar space of (MMT) by using water extract of Satureja hortensis L as reducing agent. The MMT was suspended in the aqueous AgNO₃ solution, and after the absorption of silver ions, Ag⁺ was reduced using water extract of Satureja hortensis L to Ag°. Evaluation of the antibacterial properties are also reported. The nanocomposite was characterized by ultraviolet-visible spectroscopy (UV–Vis), powder X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). TEM study showed the formation of nanocomposite using water extract of Satureja hortensis L in the 4.88 – 26.70 nm range and average particles size were 15.79 nm also the XRD study showed that the particles have a face-centered cubic (fcc) structure. The nanocomposite showed the antibacterial properties against Gram-positive and Gram-negative bacteria. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antibacterial%20effects" title="antibacterial effects">antibacterial effects</a>, <a href="https://publications.waset.org/abstracts/search?q=montmorillonite" title=" montmorillonite"> montmorillonite</a>, <a href="https://publications.waset.org/abstracts/search?q=Satureja%20hortensis%20l" title=" Satureja hortensis l"> Satureja hortensis l</a>, <a href="https://publications.waset.org/abstracts/search?q=transmission%20electron%20microscopy" title=" transmission electron microscopy"> transmission electron microscopy</a>, <a href="https://publications.waset.org/abstracts/search?q=nanocomposite" title=" nanocomposite"> nanocomposite</a> </p> <a href="https://publications.waset.org/abstracts/96619/rapid-biosynthesis-of-silver-montmorillonite-nanocomposite-using-water-extract-of-satureja-hortensis-l-and-evaluation-of-the-antibacterial-capacities" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/96619.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">169</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">15</span> GC-MS Analysis of Essential Oil From Satureja Hispidula: A Medicinal Plant from Algeria</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Habiba%20Rechek">Habiba Rechek</a>, <a href="https://publications.waset.org/abstracts/search?q=Ammar%20Haouat"> Ammar Haouat</a>, <a href="https://publications.waset.org/abstracts/search?q=Ratiba%20Mekkiou"> Ratiba Mekkiou</a>, <a href="https://publications.waset.org/abstracts/search?q=Diana%20C.%20G.%20A.%20Pinto"> Diana C. G. A. Pinto</a>, <a href="https://publications.waset.org/abstracts/search?q=Artur%20M.%20S.%20Silva"> Artur M. S. Silva</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Satureja hispidula is an aromatic and medicinal plant belonging to the family of Lamiaceae native to Algeria, just like mint or thyme. Although she is less known to the general public than her more famous cousins, this species has many therapeutic properties that have been used for centuries in traditional medicine of some regions. For generations, Satureja hispidula has been used in traditional medicine to treat various ailments, including respiratory diseases and diabetes. Its aroma, often described as close to that of mint, gives it a special interest in aromatherapy. Due to the growing interest in the beneficial properties of plant-derived essential oils, the aim of this study is to analyze the chemical composition of S. hispidula essential oil by gas chromatography coupled with mass spectrometry (GC-MS). Identifying the main constituents of essential oil will allow better understanding its chemical nature and exploring its potential for culinary and therapeutic application. The study of the essential oil of S. hispidula reveals a composition rich in 83 compounds, including menthone, pulegone and piperitone as main constituents. This gas chromatography analysis coupled with mass spectrometry provides valuable information about the chemical nature of this oil. However, more in-depth studies are needed to explore the potentially health-enhancing properties of this essential oil. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=satureja%20hispidula" title="satureja hispidula">satureja hispidula</a>, <a href="https://publications.waset.org/abstracts/search?q=GC-MS" title=" GC-MS"> GC-MS</a>, <a href="https://publications.waset.org/abstracts/search?q=essential%20oil" title=" essential oil"> essential oil</a>, <a href="https://publications.waset.org/abstracts/search?q=menthone" title=" menthone"> menthone</a>, <a href="https://publications.waset.org/abstracts/search?q=pulegone" title=" pulegone"> pulegone</a> </p> <a href="https://publications.waset.org/abstracts/188874/gc-ms-analysis-of-essential-oil-from-satureja-hispidula-a-medicinal-plant-from-algeria" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/188874.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">27</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14</span> Phenolic Compounds, Antiradical Activity, and Antioxidant Efficacy of Satureja hortensisl - Extracts in Vegetable Oil Protection</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Abolfazl%20Kamkar">Abolfazl Kamkar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Vegetable oils and fats are recognized as important components of our diet. They provide essential fatty acids, which are precursors of important hormones and control many physiological factors such as blood pressure, cholesterol level, and the reproductive system.Vegetable oils with higher contents of unsaturated fatty acids, especially polyunsaturated fatty acids (PUFAs) are more susceptible to oxidation.Protective effects of Sature jahortensis(SE) extracts in stabilizing soybean oil at different concentrations (200 and 400 ppm) were tested. Results showed that plant extracts could significantly (P< 0.05) lower the peroxide value and thiobarbituric acid value of oil during storage at 60 oC. The IC50 values for methanol and ethanol extracts were 31.5 ± 0.7 and 37.00 ± 0 µg/ml, respectively. In the β- carotene/linoleic acid system, methanol and ethanol extracts exhibited 87.5 ± 1.41% and 74.0 ±2.25 % inhibition against linoleic acid oxidation. The total phenolic and flavonoid contents of methanol and ethanol extracts were (101.58 ± 0. 26m g/ g) and (96.00 ± 0.027 mg/ g), (44.91 ± 0.14 m g/ g) and (14.30 ± 0.12 mg/ g) expressed in Gallic acid and Quercetin equivalents, respectively.These findings suggest that Satureja extracts may have potential application as natural antioxidants in the edible oil and food industry. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=satureja%20hortensis" title="satureja hortensis">satureja hortensis</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidant%20activity" title=" antioxidant activity"> antioxidant activity</a>, <a href="https://publications.waset.org/abstracts/search?q=oxidative%20stability" title=" oxidative stability"> oxidative stability</a>, <a href="https://publications.waset.org/abstracts/search?q=vegetable%20oil" title=" vegetable oil"> vegetable oil</a>, <a href="https://publications.waset.org/abstracts/search?q=extract" title=" extract"> extract</a> </p> <a href="https://publications.waset.org/abstracts/23372/phenolic-compounds-antiradical-activity-and-antioxidant-efficacy-of-satureja-hortensisl-extracts-in-vegetable-oil-protection" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/23372.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">371</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">13</span> Artificial Neural Network Regression Modelling of GC/MS Retention of Terpenes Present in Satureja montana Extracts Obtained by Supercritical Carbon Dioxide</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Strahinja%20Kova%C4%8Devi%C4%87">Strahinja Kovačević</a>, <a href="https://publications.waset.org/abstracts/search?q=Jelena%20Vladi%C4%87"> Jelena Vladić</a>, <a href="https://publications.waset.org/abstracts/search?q=Senka%20Vidovi%C4%87"> Senka Vidović</a>, <a href="https://publications.waset.org/abstracts/search?q=Zoran%20Zekovi%C4%87"> Zoran Zeković</a>, <a href="https://publications.waset.org/abstracts/search?q=Lidija%20Jevri%C4%87"> Lidija Jevrić</a>, <a href="https://publications.waset.org/abstracts/search?q=Sanja%20Podunavac%20Kuzmanovi%C4%87"> Sanja Podunavac Kuzmanović</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Supercritical extracts of highly valuated medicinal plant Satureja montana were prepared by application of supercritical carbon dioxide extraction in the carbon dioxide pressure range from 125 to 350 bar and temperature range from 40 to 60°C. Using GC/MS method of analysis chemical profiles (aromatic constituents) of S. montana extracts were obtained. Self-training artificial neural networks were applied to predict the retention time of the analyzed terpenes in GC/MS system. The best ANN model obtained was multilayer perceptron (MLP 11-11-1). Hidden activation was tanh and output activation was identity with Broyden–Fletcher–Goldfarb–Shanno training algorithm. Correlation measures of the obtained network were the following: R(training) = 0.9975, R(test) = 0.9971 and R(validation) = 0.9999. The comparison of the experimental and predicted retention times of the analyzed compounds showed very high correlation (R = 0.9913) and significant predictive power of the established neural network. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ANN%20regression" title="ANN regression">ANN regression</a>, <a href="https://publications.waset.org/abstracts/search?q=GC%2FMS" title=" GC/MS"> GC/MS</a>, <a href="https://publications.waset.org/abstracts/search?q=Satureja%20montana" title=" Satureja montana"> Satureja montana</a>, <a href="https://publications.waset.org/abstracts/search?q=terpenes" title=" terpenes"> terpenes</a> </p> <a href="https://publications.waset.org/abstracts/2742/artificial-neural-network-regression-modelling-of-gcms-retention-of-terpenes-present-in-satureja-montana-extracts-obtained-by-supercritical-carbon-dioxide" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/2742.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">452</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">12</span> Effect of Satureja khuzestanica Jamzad Supplementation on Inflammatory and Antioxidant Indicators in Type 2 Diabetes Patients: A Randomized Controlled Clinical Trial Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Maryam%20Bordbar">Maryam Bordbar</a>, <a href="https://publications.waset.org/abstracts/search?q=Yaser%20Mokhayeri"> Yaser Mokhayeri</a>, <a href="https://publications.waset.org/abstracts/search?q=Sajjad%20Roosta"> Sajjad Roosta</a>, <a href="https://publications.waset.org/abstracts/search?q=Fatemeh%20Ghasemi"> Fatemeh Ghasemi</a>, <a href="https://publications.waset.org/abstracts/search?q=Saeed%20Choobkar"> Saeed Choobkar</a>, <a href="https://publications.waset.org/abstracts/search?q=Hamidreza%20Nikbakht"> Hamidreza Nikbakht</a>, <a href="https://publications.waset.org/abstracts/search?q=Ebrahim%20Falahi"> Ebrahim Falahi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: Diabetes mellitus type 2 is the most common metabolic disorder that is growing exponentially worldwide. Satureja Khuzestanica Jamzad is a native plant of Iran that grows widely in the south of Iran. Its antimicrobial, antioxidant, anti-inflammatory and pain-relieving effects have been documented in animal studies. The purpose of this study is to investigate the effect of consumption daily S. khuzestanica on inflammatory and antioxidant indicators in type 2 diabetic patients. Methods and Materials: In a double-blind, placebo-controlled clinical trial, 67 patients with type 2 diabetes were included and divided into two groups. One group received S. khuzestanica (capsule containing 500 mg) and the other group received placebo (500 mg talcum powder) once a day for 12 weeks. After the intervention, the inflammatory and antioxidant indicators of the two groups were compared. Results: In comparison to placebo groups, there was a significant difference in levels of total antioxidant capacity, superoxide dismutase, catalase, glutathione reductase, and glutathione peroxidase; these antioxidant indicators were higher in the intervention group (P<0.05). Moreover, a considerable decrease in weight, CRP and IL-6 levels were observed in patients in the S.Khuzestanica group. Conclusion: Our findings may provide novel complementary treatments without adverse effects for diabetes complications. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Satureja%20khuzestanica%20Jamzad" title="Satureja khuzestanica Jamzad">Satureja khuzestanica Jamzad</a>, <a href="https://publications.waset.org/abstracts/search?q=diabetes%20mellitus" title=" diabetes mellitus"> diabetes mellitus</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidant%20indicators" title=" antioxidant indicators"> antioxidant indicators</a>, <a href="https://publications.waset.org/abstracts/search?q=IL-6" title=" IL-6"> IL-6</a>, <a href="https://publications.waset.org/abstracts/search?q=C-reactive%20protein" title=" C-reactive protein"> C-reactive protein</a> </p> <a href="https://publications.waset.org/abstracts/177405/effect-of-satureja-khuzestanica-jamzad-supplementation-on-inflammatory-and-antioxidant-indicators-in-type-2-diabetes-patients-a-randomized-controlled-clinical-trial-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/177405.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">70</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">11</span> Component Composition of Biologically Active Substances in Extracts of Some Species from the Family Lamiaceae Lindl.</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Galina%20N.%20Parshina">Galina N. Parshina</a>, <a href="https://publications.waset.org/abstracts/search?q=Olga%20N.%20Shemshura"> Olga N. Shemshura</a>, <a href="https://publications.waset.org/abstracts/search?q=Ulzhan%20S.%20Mukiyanova"> Ulzhan S. Mukiyanova</a>, <a href="https://publications.waset.org/abstracts/search?q=Gulnur%20M.%20Beisetbayeva"> Gulnur M. Beisetbayeva</a> </p> <p class="card-text"><strong>Abstract:</strong></p> From a medical point of view some species from the family Lamiaceae Lindl. attract the attention of scientists. Many plant species from this family are used in science and medicine. Some researchers believe that the medicinal properties of these plants are caused by the action on the organism of the individual components (camphor, menthol, thymol, eugenol, phenols, flavonoids, alcohols, and their derivatives) or the entire complex of essential oils. Biologically active substances (BAS), isolated from these medicinal plants can be an effective supplement in the complex treatment of infectious diseases. The substances of the phenolic group such as flavonoids and phenolic acids; and also alkaloids included in the component composition of the plants from the family Lamiaceae Lindl. present the scientific and practical interest for future investigations of their biological activity and development of medicinal products. The research objects are the species from the family Lamiaceae Lindl., cultivated in the North-Kazakhstan region. In this abstract, we present the results of the investigation of polyphenolic complex (flavonoids and phenolic acids) and alkaloids in aqueous and ethanol extracts. Investigation of the qualitative composition of flavonoids in the aqueous extracts showed that the species Monarda Diana contains flavone, Dracocephalum moldavica contains rutin, Ocimum basilicum (purple form) contains both ruin and quercetin. Biochemical analysis revealed that the ethanol extract of Monarda Diana has phenolic acids, similar to protocatechuic and benzoic acids by their chromatographic characteristics. But the aqueous extract contains four phenolic acids, one of which is an analogue of gentisic acid; and the other three are not identified yet. The phenolic acids such as benzoic and gentisic acids identified in ethanol extracts of species Ocimum basilicum (purple form) and Satureja hortensis, correspondingly. But the same phenolic acids did not appear in aqueous extracts. The phenolic acids were not determined neither in the ethanol or aqueous extracts of species Dracocephalum moldavica. The biochemical analysis did not reveal the content of alkaloids in aqueous extracts of investigated plants. However, the alkaloids in the amount of 5-13 components were identified in the ethanolic extracts of plants by the qualitative reactions. The results of analysis with reagent of Dragendorff showed that next amounts of alkaloids were identified in extracts of Monarda Diana (6-7), Satureja hortensis (6), Ocimum basilicum (7-9) and Dracocephalum moldavica (5-6). The reactions with reagent of Van-Urca showed that next amounts of alkaloids were identified in extracts of Monarda Diana (9-12), Satureja hortensis (9-10), two alkaloids of them with Rf6=0,39 and Rf6=0,31 similar to roquefortine), Ocimum basilicum (11) and Dracocephalum moldavica (13, two of them with Rf5=0,34 and Rf5=0,33 by their chromatographic characteristics similar to epikostaklavin). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biologically%20active%20substances" title="biologically active substances">biologically active substances</a>, <a href="https://publications.waset.org/abstracts/search?q=Lamiaceae" title=" Lamiaceae"> Lamiaceae</a>, <a href="https://publications.waset.org/abstracts/search?q=component%20composition" title=" component composition"> component composition</a>, <a href="https://publications.waset.org/abstracts/search?q=medicinal%20plant" title=" medicinal plant"> medicinal plant</a> </p> <a href="https://publications.waset.org/abstracts/18801/component-composition-of-biologically-active-substances-in-extracts-of-some-species-from-the-family-lamiaceae-lindl" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/18801.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">503</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10</span> New Method for the Synthesis of Different Pyrroloquinazolinoquinolin Alkaloids</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Abdulkareem%20M.%20Hamid">Abdulkareem M. Hamid</a>, <a href="https://publications.waset.org/abstracts/search?q=Yaseen%20Elhebshi"> Yaseen Elhebshi</a>, <a href="https://publications.waset.org/abstracts/search?q=Adam%20Da%C3%AFch"> Adam Daïch </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Luotonins and its derivatives (Isoluotonins) are alkaloids from the aerial parts of Peganum nigellastrum Bunge that display three major skeleton types. Luotonins A, B, and E are pyrroloquinazolinoquinoline alkaloids. A few methods were known for the sysnthesis of Isoluotonin. All luotonins have shown promising cytotoxicities towards selected human cancer cell lines, especially against leukemia P-388 cells. Luotonin A is the most active one, with its activity stemming from topoisomerase I-dependent DNA-cleavage. Such intriguing biological activities and unique structures have led not only to the development of synthetic methods for the efficient synthesis of these compounds, but also to interest in structural modifications for improving the biological properties. Recent progress in the study of luotonins is covered. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=luotonin%20A" title="luotonin A">luotonin A</a>, <a href="https://publications.waset.org/abstracts/search?q=isoluotonin" title=" isoluotonin"> isoluotonin</a>, <a href="https://publications.waset.org/abstracts/search?q=pyrroloquiolines" title=" pyrroloquiolines"> pyrroloquiolines</a>, <a href="https://publications.waset.org/abstracts/search?q=alkaloids" title=" alkaloids"> alkaloids</a> </p> <a href="https://publications.waset.org/abstracts/2142/new-method-for-the-synthesis-of-different-pyrroloquinazolinoquinolin-alkaloids" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/2142.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">417</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9</span> Seed Germination and Recovery Responses of Suaeda Heterophylla to Abiotic Stresses</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Abdul%20Hameed">Abdul Hameed</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20Zaheer%20Ahmed"> Muhammad Zaheer Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Salman%20Gulzar"> Salman Gulzar</a>, <a href="https://publications.waset.org/abstracts/search?q=Bilquees%20Gul"> Bilquees Gul</a>, <a href="https://publications.waset.org/abstracts/search?q=Jan%20Alam"> Jan Alam</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmad%20K.%20Hegazy"> Ahmad K. Hegazy</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdel%20Rehman%20A.%20Alatar"> Abdel Rehman A. Alatar</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Ajmal%20Khan"> M. Ajmal Khan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Seed germination and recovery from salt stress of an annual halophyte Suaeda heterophylla (Kar. and Kir.) Bunge to different iso-osmotic concentrations (0, -0.46, -0.92, -1.38, -1.84, and -2.30 MPa) of NaCl and PEG-6000 at 15/25, 20/30 and 25/35°C in both 12-h temperature and light regimes and in complete darkness were studied. Maximum number of seeds germinated in distilled water and increase in concentrations of both NaCl and PEG-6000 decreased germination at all temperature regimes, light and dark conditions, with higher inhibition in NaCl than PEG-6000. Recovery of germination and viability of seeds were lower in NaCl than PEG-6000 both in the light and dark. Moderate alternate temperatures (20/30°C) and 12-h photoperiod were found to be the optimal for seed germination and recovery. Better seed germination of S. heterophylla when osmotic potential caused both by NaCl and PEG 6000 is lower, temperature regime of 20/30°C and light regime is for 12 h. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=seed%20germination" title="seed germination">seed germination</a>, <a href="https://publications.waset.org/abstracts/search?q=abiotic%20stresses" title=" abiotic stresses"> abiotic stresses</a>, <a href="https://publications.waset.org/abstracts/search?q=Suaeda%20heterophylla" title=" Suaeda heterophylla"> Suaeda heterophylla</a>, <a href="https://publications.waset.org/abstracts/search?q=molecular%20biology" title=" molecular biology"> molecular biology</a> </p> <a href="https://publications.waset.org/abstracts/2254/seed-germination-and-recovery-responses-of-suaeda-heterophylla-to-abiotic-stresses" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/2254.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">438</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">8</span> Calycosin Ameliorates Osteoarthritis by Regulating the Imbalance Between Chondrocyte Synthesis and Catabolism</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hong%20Su">Hong Su</a>, <a href="https://publications.waset.org/abstracts/search?q=Qiuju%20Yan"> Qiuju Yan</a>, <a href="https://publications.waset.org/abstracts/search?q=Wei%20Du"> Wei Du</a>, <a href="https://publications.waset.org/abstracts/search?q=En%20Hu"> En Hu</a>, <a href="https://publications.waset.org/abstracts/search?q=Zhaoyu%20Yang"> Zhaoyu Yang</a>, <a href="https://publications.waset.org/abstracts/search?q=Wei%20Zhang"> Wei Zhang</a>, <a href="https://publications.waset.org/abstracts/search?q=Yusheng%20Li"> Yusheng Li</a>, <a href="https://publications.waset.org/abstracts/search?q=Tao%20Tang"> Tao Tang</a>, <a href="https://publications.waset.org/abstracts/search?q=Wang%20yang"> Wang yang</a>, <a href="https://publications.waset.org/abstracts/search?q=Shushan%20Zhao"> Shushan Zhao</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Osteoarthritis (OA) is a severe chronic inflammatory disease. As the main active component of Astragalus mongholicus Bunge, a classic traditional ethnic herb, calycosin exhibits anti-inflammatory action and its mechanism of exact targets for OA have yet to be determined. In this study, we established an anterior cruciate ligament transection (ACLT) mouse model. Mice were randomized to sham, OA, and calycosin groups. Cartilage synthesis markers type II collagen (Col-2) and SRY-Box Transcription Factor 9 (Sox-9) increased significantly after calycosin gavage. While cartilage matrix degradation index cyclooxygenase-2 (COX-2), phosphor-epidermal growth factor receptor (p-EGFR), and matrix metalloproteinase-9 (MMP9) expression were decreased. With the help of network pharmacology and molecular docking, these results were confirmed in chondrocyte ATDC5 cells. Our results indicated that the calycosin treatment significantly improved cartilage damage, this was probably attributed to reversing the imbalance between chondrocyte synthesis and catabolism. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=calycosin" title="calycosin">calycosin</a>, <a href="https://publications.waset.org/abstracts/search?q=osteoarthritis" title=" osteoarthritis"> osteoarthritis</a>, <a href="https://publications.waset.org/abstracts/search?q=network%20pharmacology" title=" network pharmacology"> network pharmacology</a>, <a href="https://publications.waset.org/abstracts/search?q=molecular%20docking" title=" molecular docking"> molecular docking</a>, <a href="https://publications.waset.org/abstracts/search?q=inflammatory" title=" inflammatory"> inflammatory</a>, <a href="https://publications.waset.org/abstracts/search?q=cyclooxygenase%202" title=" cyclooxygenase 2"> cyclooxygenase 2</a> </p> <a href="https://publications.waset.org/abstracts/163698/calycosin-ameliorates-osteoarthritis-by-regulating-the-imbalance-between-chondrocyte-synthesis-and-catabolism" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/163698.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">102</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">7</span> Activation of AMPK-TSC axis is involved in cryptotanshinone inhibition of mTOR signaling in cancer cells </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Wenxing%20Chen">Wenxing Chen</a>, <a href="https://publications.waset.org/abstracts/search?q=Guangying%20Chen"> Guangying Chen</a>, <a href="https://publications.waset.org/abstracts/search?q=Yin%20Lu"> Yin Lu</a>, <a href="https://publications.waset.org/abstracts/search?q=Shile%20Huang"> Shile Huang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Cryptotanshinone (CPT), a fat-soluble tanshinone from Salvia miltiorrhiza Bunge, has been demonstrated to inhibit mTOR pathway, resulting in inhibition of cancer cell proliferation. However, the molecular mechanism how CPT acts on mTOR is unknown. Here, cancer cells expressing rapamycin-resistant mutant mTOR are also sensitive to CPT, while phosphorylation of AMPK and TSC2 was activated, suggesting that CPT inhibition of mTOR maybe due to activating upstream of mTOR, AMPK, but not directly binding to and inhibiting mTOR. Further results indicated that Compound C, inhibitor of AMPK, could partially reversed CPT inhibition effect on cancer cells, and dominant-negative AMPK in cancer cells conferred resistance to CPT inhibition of 4EBP1 and phosphorylation of S6K1, as well as sh-AMPK. Furthermore, compared with MEF cells with AMPK positive, MEF cells with AMPK knock out are less sensitive to CPT by the findings that 4E-BP1 and phosphorylation of S6K1 express comparatively much. Furthermore, downexpression of TSC2 slightly recovered expression of 4EBP1 and phosphorylation of S6K1, while co-immunoprecipitation of TSC2 did not affect expression of TSC1 by CPT. Collectively, the above-mentioned results suggest that CPT inhibited mTOR pathway mostly was due to activation of AMPK-TSC2 pathway rather than specific inhibition of mTOR and then induction of subsequent lethal cellular effect. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cryptotanshinone" title="cryptotanshinone">cryptotanshinone</a>, <a href="https://publications.waset.org/abstracts/search?q=AMPK" title=" AMPK"> AMPK</a>, <a href="https://publications.waset.org/abstracts/search?q=TSC2" title=" TSC2"> TSC2</a>, <a href="https://publications.waset.org/abstracts/search?q=mTOR" title=" mTOR"> mTOR</a>, <a href="https://publications.waset.org/abstracts/search?q=cancer%20cells" title=" cancer cells"> cancer cells</a> </p> <a href="https://publications.waset.org/abstracts/2970/activation-of-ampk-tsc-axis-is-involved-in-cryptotanshinone-inhibition-of-mtor-signaling-in-cancer-cells" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/2970.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">490</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6</span> Substitution of Silver-Thiosulfate (STS) with Some Essential Oils on Vase-Life of Cut Carnation cv. Liberty</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Bagher%20Hassanpouraghdam">Mohammad Bagher Hassanpouraghdam</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Ali%20Aazami%20Mavaloo"> Mohammad Ali Aazami Mavaloo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Due to the huge side-effects of chemicals; essential oils have been considered as suitable alternatives for keeping the vase-life of cut flowers mainly owing to the availability and environment-friend nature of these bio-chemicals. In the present experiment, 50% substitution of STS was achieved and tested on cut carnation flowers cv. Liberty by using the essential oils from four plants; Satureja sahendica Bornm., Echinophora platyloba DC., Tanacetum balsamita L. and Cupressus arizonica Greene., as CRD with five treatments and 3 replications. Vase-life and flower diameter were affected with 50% substitution of STS by essential oils from C. arizonica and T. balsamita. Membrane stability index, Malondialdehyde (MDA) content and Hydrogen peroxide (H2O2) amounts were affected by the substitution treatments as well. The main preservative effect belonged to the substitution with C. arizonica. So that, 50% STS substitution with Cupressus oil holds the highest membrane integrity and the least data for MDA and H2O2 content. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Carnation" title="Carnation">Carnation</a>, <a href="https://publications.waset.org/abstracts/search?q=essential%20oil" title=" essential oil"> essential oil</a>, <a href="https://publications.waset.org/abstracts/search?q=Membrane%20stability%20index%20%28MSI%29" title=" Membrane stability index (MSI)"> Membrane stability index (MSI)</a>, <a href="https://publications.waset.org/abstracts/search?q=vase%20life" title=" vase life"> vase life</a> </p> <a href="https://publications.waset.org/abstracts/55028/substitution-of-silver-thiosulfate-sts-with-some-essential-oils-on-vase-life-of-cut-carnation-cv-liberty" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/55028.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">496</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> The Effects of Sewage Sludge Usage and Manure on Some Heavy Metals Uptake in Savory (Satureja Hortensis L.)</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Abbas%20Hani">Abbas Hani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In recent decades with the development of technology and lack of food sources, sewage sludge in production of human foods is inevitable. Various sources of municipal and industrial sewage sludge that is produced can provide the requirement of plant nutrients. Soils in arid, semi-arid climate of central Iran that most affected by water drainage, iron and zinc deficiencies, using of sewage sludge is helpful. Therefore, the aim of this study is investigation of sewage sludge and manure application on Ni and Zn uptake by Savory. An experiment in a randomized complete block design with three replications was performed. Sewage sludge treatments consisted of four levels, control, 15, 30, 80 tons per hectares, the manure was used in four levels of control, 20, 40 and 80 tons per hectare. Results showed that the wet and dry weights was not affected by sewage sludge using, while, manure has significant effect on them. The effect of sewage sludge on the cadmium and lead concentrations were significant. Interactions of sewage sludge and manure on dry weight values were not significant. Compare mean analysis showed that increasing the amount of sewage sludge had no significant effect on cadmium concentration and it reduced when sewage sludge usage increased. This is probably due to increased plant growth and reduced concentrations of these elements in the plant. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=savory" title="savory">savory</a>, <a href="https://publications.waset.org/abstracts/search?q=lead" title=" lead"> lead</a>, <a href="https://publications.waset.org/abstracts/search?q=cadmium" title=" cadmium"> cadmium</a>, <a href="https://publications.waset.org/abstracts/search?q=sewage%20sludge" title=" sewage sludge"> sewage sludge</a>, <a href="https://publications.waset.org/abstracts/search?q=manure" title=" manure"> manure</a> </p> <a href="https://publications.waset.org/abstracts/18651/the-effects-of-sewage-sludge-usage-and-manure-on-some-heavy-metals-uptake-in-savory-satureja-hortensis-l" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/18651.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">420</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> Encapsulation of Satureja khuzestanica Essential Oil in Chitosan Nanoparticles with Enhanced Antifungal Activity</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Amir%20Amiri">Amir Amiri</a>, <a href="https://publications.waset.org/abstracts/search?q=Naghmeh%20Morakabati"> Naghmeh Morakabati</a> </p> <p class="card-text"><strong>Abstract:</strong></p> During the recent years the six-fold growth of cancer in Iran has led the production of healthy products to become a challenge in the food industry. Due to the young population in the country, the consumption of fast foods is growing. The chemical cancer-causing preservatives are used to produce these products more than the standard; so using an appropriate alternative seems to be important. On the one hand, the plant essential oils show the high antimicrobial potential against pathogenic and spoilage microorganisms and on the other hand they are highly volatile and decomposed under the processing conditions. The study aims to produce the loaded chitosan nanoparticles with different concentrations of savory essential oil to improve the anti-microbial property and increase the resistance of essential oil to oxygen and heat. The encapsulation efficiency was obtained in the range of 32.07% to 39.93% and the particle size distribution of the samples was observed in the range of 159 to 210 nm. The range of Zeta potential was obtained between -11.9 to -23.1 mV. The essential oil loaded in chitosan showed stronger antifungal activity against <em>Rhizopus stolonifer</em>. The results showed that the antioxidant property is directly related to the concentration of loaded essential oil so that the antioxidant property increases by increasing the concentration of essential oil. In general, it seems that the savory essential oil loaded in chitosan particles can be used as a food processor. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chitosan" title="chitosan">chitosan</a>, <a href="https://publications.waset.org/abstracts/search?q=encapsulation" title=" encapsulation"> encapsulation</a>, <a href="https://publications.waset.org/abstracts/search?q=essential%20oil" title=" essential oil"> essential oil</a>, <a href="https://publications.waset.org/abstracts/search?q=nanogel" title=" nanogel"> nanogel</a> </p> <a href="https://publications.waset.org/abstracts/53794/encapsulation-of-satureja-khuzestanica-essential-oil-in-chitosan-nanoparticles-with-enhanced-antifungal-activity" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/53794.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">274</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Medicinal and Aromatic Plants of Ardanuç (Artvi̇n, Türki̇ye)</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=%C3%96zg%C3%BCr%20Emi%CC%87na%C4%9Fao%C4%9Flu">Özgür Emi̇nağaoğlu</a>, <a href="https://publications.waset.org/abstracts/search?q=Hayal%20Akyildirim%20Be%C4%9Fen"> Hayal Akyildirim Beğen</a>, <a href="https://publications.waset.org/abstracts/search?q=%C5%9Eevval%20Sali%CC%87o%C4%9Flu"> Şevval Sali̇oğlu</a>, <a href="https://publications.waset.org/abstracts/search?q=Emrah%20Y%C3%BCksel"> Emrah Yüksel</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study was carried out in order to determine the scientific name, common name, local names, location, botanical characteristics, used parts, intended use, local usage patterns, usage in the literature of plant species used for medicinal and aromatic purposes in Ardanuç (Artvin, Türkiye) between 2020-2023 years. The research area is located in the A9 square according to Davis’s grid system and is phytogeographically located in the colchic subsection of the Euxine part of the Euro-Siberian flora area of the Holarctic region. As a result of the studies, it has been determined that 167 plant species belonging to 79 families are used for medicinal and aromatic purposes. The families that contain the most taxa in the research area are, respectively, Rosaceae (19 taxa), Asterecaeae (15 taxa), and Lamiaceae (14 taxa). It has been determined that the medicinal, aromatic plants of the Ardanuç region are mostly used in the treatment of diseases (59%), and the plants are mostly used in the treatment of diabetes (37%). It was determined that the most applied method in the internal use of plants was decoction (48%). As a result of the research, the most commonly used plants in different diseases are Sambucus nigra, Plantago lanceolata, Satureja hortensis, Hypericum perforatum, Juniperus communis. These plants are used in the treatment of many diseases, such as colds, cancer, anemia and diabetes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ardanu%C3%A7" title="Ardanuç">Ardanuç</a>, <a href="https://publications.waset.org/abstracts/search?q=Artvin" title=" Artvin"> Artvin</a>, <a href="https://publications.waset.org/abstracts/search?q=Medicinal%20and%20Aromatic%20plant" title=" Medicinal and Aromatic plant"> Medicinal and Aromatic plant</a>, <a href="https://publications.waset.org/abstracts/search?q=T%C3%BCrkiye" title=" Türkiye"> Türkiye</a> </p> <a href="https://publications.waset.org/abstracts/171408/medicinal-and-aromatic-plants-of-ardanuc-artvin-turkiye" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/171408.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">74</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Study of the Protective Effects of Summer Savory against Multiple Organ Damage Induced by Lead Acetate in Rats</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bassant%20M.%20M.%20Ibrahim">Bassant M. M. Ibrahim</a>, <a href="https://publications.waset.org/abstracts/search?q=Doha%20H.%20Abou%20Baker"> Doha H. Abou Baker</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20Abd%20Elghafour"> Ahmed Abd Elghafour </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Excessive exposure to heavy metals contributes to the occurrence of deleterious health problems that affect vital organs like the brain, liver, kidneys, and heart. The use of natural products that have antioxidant capabilities may contribute to the protection of these organs. In the present study, the essential oil of summer savory (Satureja hortensis) was used to evaluate its protective effects against lead acetate induced damaging effect on rats’ vital organs, due to its high contents of carvacrol, y-terpinene, and p-cymene. Forty female Wister Albino rats were classified into five equal groups, the 1st served as normal group, the 2nd served as positive control group was given lead acetate (60 mg/kg) intra-peritoneal (IP), the third to fifth groups were treated with calcium disodium (EDTA) as chelating agent and summer savory essential oil in doses of (50 and 100mg/kg) respectively. All treatments were given IP concomitant with lead acetate for ten successive days. At the end of the experiment duration electrocardiogram (ECG), an open field test for the evaluation of psychological state, rotarod test as for the evaluation of locomotor coordination ability as well as anti-inflammatory and oxidative stress biomarkers in serum and histopathology of vital organs were performed. The investigations in this study show that the protective effect of high dose of summer savory essential oil is more than the low dose and that the essential oil of summer savory is a promising agent that can contribute to the protection of vital organs against the hazardous damaging effects of lead acetate. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=brain" title="brain">brain</a>, <a href="https://publications.waset.org/abstracts/search?q=heart" title=" heart"> heart</a>, <a href="https://publications.waset.org/abstracts/search?q=kidneys" title=" kidneys"> kidneys</a>, <a href="https://publications.waset.org/abstracts/search?q=lead%20acetate" title=" lead acetate"> lead acetate</a>, <a href="https://publications.waset.org/abstracts/search?q=liver" title=" liver"> liver</a>, <a href="https://publications.waset.org/abstracts/search?q=protective" title=" protective"> protective</a>, <a href="https://publications.waset.org/abstracts/search?q=summer%20savory" title=" summer savory"> summer savory</a> </p> <a href="https://publications.waset.org/abstracts/104643/study-of-the-protective-effects-of-summer-savory-against-multiple-organ-damage-induced-by-lead-acetate-in-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/104643.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">123</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Antibacterial Effects of Some Medicinal and Aromatic Plant Extracts on Pathogenic Bacteria Isolated from Pear Orchards</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kubilay%20Kurtulus%20Bastas">Kubilay Kurtulus Bastas</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Bacterial diseases are very destructive and cause economic losses on pears. Promising plant extracts for the management of plant diseases are environmentally safe, long-lasting and extracts of certain plants contain alkaloids, tannins, quinones, coumarins, phenolic compounds, and phytoalexins. In this study, bacteria were isolated from different parts of pear exhibiting characteristic symptoms of bacterial diseases from the Central Anatolia, Turkey. Pathogenic bacteria were identified by morphological, physiological, biochemical and molecular methods as fire blight (Erwinia amylovora (39%)), bacterial blossom blast and blister bark (Pseudomonas syringae pv. syringae (22%)), crown gall (Rhizobium radiobacter (1%)) from different pear cultivars, and determined virulence levels of the pathogens with pathogenicity tests. The air-dried 25 plant material was ground into fine powder and extraction was performed at room temperature by maceration with 80% (v/v) methanol/distilled water. The minimum inhibitory concentration (MIC) values were determined by using modified disc diffusion method at five different concentrations and streptomycin sulphate was used as control chemical. Bacterial suspensions were prepared as 108 CFU ml⁻¹ densities and 100 µl bacterial suspensions were spread to TSA medium. Antimicrobial activity was evaluated by measuring the inhibition zones in reference to the test organisms. Among the tested plants, Origanum vulgare, Hedera helix, Satureja hortensis, Rhus coriaria, Eucalyptus globulus, Rosmarinus officinalis, Ocimum basilicum, Salvia officinalis, Cuminum cyminum and Thymus vulgaris showed a good antibacterial activity and they inhibited the growth of the pathogens with inhibition zone diameter ranging from 7 to 27 mm at 20% (w/v) in absolute methanol in vitro conditions. In vivo, the highest efficacy was determined as 27% on reducing tumor formation of R. radiobacter, and 48% and 41% on reducing shoot blight of E. amylovora and P. s. pv. syringae on pear seedlings, respectively. Obtaining data indicated that some plant extracts may be used against the bacterial diseases on pome fruits within sustainable and organic management programs. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bacteria" title="bacteria">bacteria</a>, <a href="https://publications.waset.org/abstracts/search?q=eco-friendly%20management" title=" eco-friendly management"> eco-friendly management</a>, <a href="https://publications.waset.org/abstracts/search?q=organic" title=" organic"> organic</a>, <a href="https://publications.waset.org/abstracts/search?q=pear" title=" pear"> pear</a>, <a href="https://publications.waset.org/abstracts/search?q=plant%20extract" title=" plant extract "> plant extract </a> </p> <a href="https://publications.waset.org/abstracts/81905/antibacterial-effects-of-some-medicinal-and-aromatic-plant-extracts-on-pathogenic-bacteria-isolated-from-pear-orchards" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/81905.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">335</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Account <li><a href="https://waset.org/profile">My Account</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Explore <li><a href="https://waset.org/disciplines">Disciplines</a></li> <li><a href="https://waset.org/conferences">Conferences</a></li> <li><a href="https://waset.org/conference-programs">Conference Program</a></li> <li><a href="https://waset.org/committees">Committees</a></li> <li><a href="https://publications.waset.org">Publications</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Research <li><a href="https://publications.waset.org/abstracts">Abstracts</a></li> <li><a href="https://publications.waset.org">Periodicals</a></li> <li><a href="https://publications.waset.org/archive">Archive</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Open Science <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Philosophy.pdf">Open Science Philosophy</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Award.pdf">Open Science Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Society-Open-Science-and-Open-Innovation.pdf">Open Innovation</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Postdoctoral-Fellowship-Award.pdf">Postdoctoral Fellowship Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Scholarly-Research-Review.pdf">Scholarly Research Review</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Support <li><a href="https://waset.org/page/support">Support</a></li> <li><a href="https://waset.org/profile/messages/create">Contact Us</a></li> <li><a href="https://waset.org/profile/messages/create">Report Abuse</a></li> </ul> </div> </div> </div> </div> </div> <div class="container text-center"> <hr style="margin-top:0;margin-bottom:.3rem;"> <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" class="text-muted small">Creative Commons Attribution 4.0 International License</a> <div id="copy" class="mt-2">© 2024 World Academy of Science, Engineering and Technology</div> </div> </footer> <a href="javascript:" id="return-to-top"><i class="fas fa-arrow-up"></i></a> <div class="modal" id="modal-template"> <div class="modal-dialog"> <div class="modal-content"> <div class="row m-0 mt-1"> <div class="col-md-12"> <button type="button" class="close" data-dismiss="modal" aria-label="Close"><span aria-hidden="true">×</span></button> </div> </div> <div class="modal-body"></div> </div> </div> </div> <script src="https://cdn.waset.org/static/plugins/jquery-3.3.1.min.js"></script> <script src="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/js/bootstrap.bundle.min.js"></script> <script src="https://cdn.waset.org/static/js/site.js?v=150220211556"></script> <script> jQuery(document).ready(function() { /*jQuery.get("https://publications.waset.org/xhr/user-menu", function (response) { jQuery('#mainNavMenu').append(response); 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