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isotope (chemistry) | Britannica

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mb-20"> <div class="font-serif font-14 font-weight-bold mx-15 mb-15 mt-20"> Table of Contents </div> <ul class="list-unstyled my-0" data-level="h1"><li data-target="#ref1"><div class="pl-25"><a class="link-gray-900 w-100" href="/science/isotope">Introduction & Top Questions</a></div><div class="ml-40 toc-drawer sub-toc-drawer"></div></li><li data-target="#ref48249"><div class="d-flex align-items-center"><div class="ml-25"></div><a class="w-100 link-gray-900" href="/science/isotope/The-discovery-of-isotopes">The discovery of isotopes</a></div><div class="ml-40 toc-drawer sub-toc-drawer"></div></li><li data-target="#ref48250"><div class="d-flex align-items-center"><div class="ml-25"></div><a class="w-100 link-gray-900" href="/science/isotope/The-discovery-of-isotopes#ref48250">Nuclear stability</a></div><div class="ml-40 toc-drawer sub-toc-drawer"></div></li><li data-target="#ref48251"><div class="d-flex align-items-center"><div class="ml-25"></div><a class="w-100 link-gray-900" href="/science/isotope/The-discovery-of-isotopes#ref48251">Radioactive isotopes</a></div><div class="ml-40 toc-drawer sub-toc-drawer"></div></li><li data-target="#ref48252"><div class="d-flex align-items-center"><div class="ml-25"></div><a class="w-100 link-gray-900" href="/science/isotope/Elemental-and-isotopic-abundances">Elemental and isotopic abundances</a></div><div class="ml-40 toc-drawer sub-toc-drawer"></div></li><li data-target="#ref48253"><div class="d-flex align-items-center"><button class="h1-link-drawer-button btn btn-xs btn-circle d-flex rounded" type="button" aria-label="Toggle Heading"><em class="material-icons font-18" data-icon="keyboard_arrow_right"></em></button><a class="w-100 link-gray-900" href="/science/isotope/Variations-in-isotopic-abundances">Variations in isotopic abundances</a></div><div class="ml-40 toc-drawer sub-toc-drawer"><ul class="list-unstyled" data-level="h2"><li data-target="#ref48254"><a class="w-100 link-gray-900" href="/science/isotope/Variations-in-isotopic-abundances#ref48254">Radioactive decay</a></li></ul><ul class="list-unstyled" data-level="h2"><li data-target="#ref48255"><a class="w-100 link-gray-900" href="/science/isotope/Variations-in-isotopic-abundances#ref48255">Mass fractionation</a></li></ul><ul class="list-unstyled" data-level="h2"><li data-target="#ref48256"><a class="w-100 link-gray-900" href="/science/isotope/Variations-in-isotopic-abundances#ref48256">Other causes of isotopic abundance variations</a></li></ul></div></li><li data-target="#ref48257"><div class="d-flex align-items-center"><div class="ml-25"></div><a class="w-100 link-gray-900" href="/science/isotope/Variations-in-isotopic-abundances#ref48257">Physical properties associated with isotopes</a></div><div class="ml-40 toc-drawer sub-toc-drawer"></div></li><li data-target="#ref48258"><div class="d-flex align-items-center"><button class="h1-link-drawer-button btn btn-xs btn-circle d-flex rounded" type="button" aria-label="Toggle Heading"><em class="material-icons font-18" data-icon="keyboard_arrow_right"></em></button><a class="w-100 link-gray-900" href="/science/isotope/Variations-in-isotopic-abundances#ref48258">Effect of isotopes on atomic and molecular spectra</a></div><div class="ml-40 toc-drawer sub-toc-drawer"><ul class="list-unstyled" data-level="h2"><li data-target="#ref48259"><a class="w-100 link-gray-900" href="/science/isotope/Molecular-vibrations">Molecular vibrations</a></li></ul><ul class="list-unstyled" data-level="h2"><li data-target="#ref48260"><a class="w-100 link-gray-900" href="/science/isotope/Molecular-vibrations#ref48260">Importance in the study of polyatomic molecules</a></li></ul></div></li><li data-target="#ref48261"><div class="d-flex align-items-center"><div class="ml-25"></div><a class="w-100 link-gray-900" href="/science/isotope/Molecular-vibrations#ref48261">Chemical effects of isotopic substitution</a></div><div class="ml-40 toc-drawer sub-toc-drawer"></div></li><li data-target="#ref48262"><div class="d-flex align-items-center"><div class="ml-25"></div><a class="w-100 link-gray-900" href="/science/isotope/Molecular-vibrations#ref48262">Effect of isotopic substitution on reaction rates</a></div><div class="ml-40 toc-drawer sub-toc-drawer"></div></li><li data-target="#ref48263"><div class="d-flex align-items-center"><button class="h1-link-drawer-button btn btn-xs btn-circle d-flex rounded" type="button" aria-label="Toggle Heading"><em class="material-icons font-18" data-icon="keyboard_arrow_right"></em></button><a class="w-100 link-gray-900" href="/science/isotope/Isotope-separation-and-enrichment">Isotope separation and enrichment</a></div><div class="ml-40 toc-drawer sub-toc-drawer"><ul class="list-unstyled" data-level="h2"><li data-target="#ref48264"><a class="w-100 link-gray-900" href="/science/isotope/Isotope-separation-and-enrichment#ref48264">Mass spectrometry</a></li></ul><ul class="list-unstyled" data-level="h2"><li data-target="#ref48265"><a class="w-100 link-gray-900" href="/science/isotope/Isotope-separation-and-enrichment#ref48265">Distillation</a></li></ul><ul class="list-unstyled" data-level="h2"><li data-target="#ref48266"><a class="w-100 link-gray-900" href="/science/isotope/Isotope-separation-and-enrichment#ref48266">Chemical exchange reactions</a></li></ul><ul class="list-unstyled" data-level="h2"><li data-target="#ref48267"><a class="w-100 link-gray-900" href="/science/isotope/Isotope-separation-and-enrichment#ref48267">Gaseous diffusion</a></li></ul><ul class="list-unstyled" data-level="h2"><li data-target="#ref48268"><a class="w-100 link-gray-900" href="/science/isotope/Isotope-separation-and-enrichment#ref48268">Gas centrifugation</a></li></ul><ul class="list-unstyled" data-level="h2"><li data-target="#ref48269"><a class="w-100 link-gray-900" href="/science/isotope/Isotope-separation-and-enrichment#ref48269">Photochemical enrichment methods</a></li></ul></div></li></ul> <a class="toc-extra-link link-gray-900" href="https://www.britannica.com/science/isotope/additional-info">References &amp; Edit History</a> <a class="toc-extra-link link-gray-900" href="/facts/isotope">Related Topics</a> </div> <div class="tlr-media-slider pb-10 mb-30"> <a class="section-header link-gray-900 font-serif font-14 font-weight-bold mb-10 mx-10 selected" href="https://www.britannica.com/science/isotope/images-videos">Images & Videos</a> <div class="slider js-slider position-relative d-inline-flex align-items-center mw-100 "> <div class="slider-container js-slider-container overflow-hidden d-flex overflow-hidden text-nowrap ml-15"> <a href="/video/What-are-isotopes/246891" data-href="/media/1/296583/246891" class="media-overlay-link d-inline-block mr-5"> <div class="position-relative --aspect-ratio: 16/9"> <img loading="lazy" src="https://cdn.britannica.com/64/216564-138-51A467D7/What-are-isotopes.jpg?w=400&h=225&c=crop" alt="What are 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id="md-topic-media-browse-list"> <div id="Videos"> <div id="Videos-isotope" class="pt-20 pb-30 border-top "> <h2> Videos</h2> </div> <div class="grid g-20"> <div class="md-topic-media-browse-list-item col-50 col-sm-33 col-lg-25 md-topic-media-browse-video"> <div style="--aspect-ratio: 16/9"> <a href="https://www.britannica.com/video/What-are-isotopes/-246891" class="w-100 d-flex justify-content-center align-items-center media-overlay-link bg-black" data-href="/media/1/296583/246891"> <img loading="lazy" src="https://cdn.britannica.com/64/216564-138-51A467D7/What-are-isotopes.jpg?w=315" alt="What are isotopes and how do they work?" class="o-70 h-100" /> <div class="position-absolute top-0 left-0 h-100 w-100 d-flex justify-content-center align-items-center"> <em class="material-icons link-white md-36" data-icon="play_arrow"></em> </div> </a> </div> <a href="https://www.britannica.com/video/What-are-isotopes/-246891" class="font-weight-bold font-12 lh-sm my-10 d-block media-overlay-link " 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isotopes...</div> <div class="credit lh-sm mt-10"> Encyclop忙dia Britannica, Inc.</div> </div> </div> </div> </div> <div class="border-top-10 border-top-blue-dark my-50 border-bottom"> <div class="font-20 py-20"><strong>VIEW MORE</strong> in these related Britannica articles:</div> <ul class="list-unstyled md-topic-media-related grid"> <li class="col-md-25 col-50"> <a href="https://www.britannica.com/science/transuranium-element/images-videos"> <img loading="lazy" src="https://cdn.britannica.com/45/7445-050-BB332C27/version-periodic-table-elements.jpg?w=300&h=150" alt="periodic table" /> <div class="title mt-10">Media for: transuranium element</div> </a> </li> <li class="col-md-25 col-50"> <a href="https://www.britannica.com/science/uranium-235/images-videos"> <img loading="lazy" src="https://cdn.britannica.com/92/62992-050-D75534B6/neutron-impact-nuclei-nucleus-uranium-isotope-any.jpg?w=300&h=150" alt="Nuclear fission" /> <div class="title mt-10">Media for: uranium-235</div> </a> </li> 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