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overflow: hidden; text-overflow: ellipsis; -webkit-line-clamp: 3; -webkit-box-orient: vertical; }</style><div class="col-xs-12 clearfix"><div class="u-floatLeft"><h1 class="PageHeader-title u-m0x u-fs30">Risk Factors</h1><div class="u-tcGrayDark">19,118 Followers</div><div class="u-tcGrayDark u-mt2x">Recent papers in <b>Risk Factors</b></div></div></div></div></div></div><div class="TabbedNavigation"><div class="container"><div class="row"><div class="col-xs-12 clearfix"><ul class="nav u-m0x u-p0x list-inline u-displayFlex"><li class="active"><a href="https://www.academia.edu/Documents/in/Risk_Factors-1">Top Papers</a></li><li><a href="https://www.academia.edu/Documents/in/Risk_Factors-1/MostCited">Most Cited Papers</a></li><li><a href="https://www.academia.edu/Documents/in/Risk_Factors-1/MostDownloaded">Most Downloaded Papers</a></li><li><a href="https://www.academia.edu/Documents/in/Risk_Factors-1/MostRecent">Newest Papers</a></li><li><a class="" href="https://www.academia.edu/People/Risk_Factors-1">People</a></li></ul></div><style type="text/css">ul.nav{flex-direction:row}@media(max-width: 567px){ul.nav{flex-direction:column}.TabbedNavigation li{max-width:100%}.TabbedNavigation li.active{background-color:var(--background-grey, #dddde2)}.TabbedNavigation li.active:before,.TabbedNavigation li.active:after{display:none}}</style></div></div></div><div class="container"><div class="row"><div class="col-xs-12"><div class="u-displayFlex"><div class="u-flexGrow1"><div class="works"><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_11579814" data-work_id="11579814" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/11579814/Predicting_child_maltreatment_in_the_first_4_years_of_life_from_characteristics_assessed_in_the_neonatal_period">Predicting child maltreatment in the first 4 years of life from characteristics assessed in the neonatal period</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objective: To examine the significance of neonatal risk factors from the individual, family, social, and parenting behavior domains of the ecological model of child maltreatment in predicting maltreatment reports in the first 4 years of... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_11579814" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objective: To examine the significance of neonatal risk factors from the individual, family, social, and parenting behavior domains of the ecological model of child maltreatment in predicting maltreatment reports in the first 4 years of life, and to examine the extent to which the interactions of life event stress and social support modify those risk factors. Method: Mothers of 708 predominantly at-risk infants were interviewed in their homes soon after their infants' discharge from the hospital. State child abuse and neglect central registry data were tracked every 6 months until the infants reached their fourth birthdays. Results: The incidence of maltreatment reports was higher in households where the mothers were depressed, complained of psychosomatic symptoms, had not graduated from high school, consumed alcohol, participated in public income support programs, cared for more than one dependent child, or were separated from their own mothers at age 14 years (p Ͻ .1). In interaction models including these seven predisposing variables, there were significant interactions (p Ͻ .01) between social support, as measured by the social well-being index after the birth of the index child, and depression, and between social well-being and stress, as measured by an increase in total life events. Conclusion: Some predisposing risk factors measured soon after birth continue to be significant predictors of child maltreatment reports through the fourth year of life. In general, families with low levels of social support had a higher risk of a maltreatment report. For families with lower levels of maternal depression and/or life event stress, low social support significantly increased the risk of a maltreatment report by as much as a factor of four.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/11579814" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="36be42328ab09966c1fc5056ba27ff94" rel="nofollow" data-download="{"attachment_id":46622130,"asset_id":11579814,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46622130/download_file?st=MTczOTk5NjI5Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="28270985" href="https://unc.academia.edu/DorothyBrowne">Dorothy Browne</a><script data-card-contents-for-user="28270985" type="text/json">{"id":28270985,"first_name":"Dorothy","last_name":"Browne","domain_name":"unc","page_name":"DorothyBrowne","display_name":"Dorothy Browne","profile_url":"https://unc.academia.edu/DorothyBrowne?f_ri=620049","photo":"https://0.academia-photos.com/28270985/15148590/15845579/s65_dorothy.browne.jpg"}</script></span></span></li><li class="js-paper-rank-work_11579814 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="11579814"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 11579814, container: ".js-paper-rank-work_11579814", }); });</script></li><li class="js-percentile-work_11579814 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 11579814; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_11579814"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_11579814 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="11579814"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 11579814; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=11579814]").text(description); $(".js-view-count-work_11579814").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_11579814").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="11579814"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">26</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="940" rel="nofollow" href="https://www.academia.edu/Documents/in/Social_Work">Social Work</a>, <script data-card-contents-for-ri="940" type="text/json">{"id":940,"name":"Social Work","url":"https://www.academia.edu/Documents/in/Social_Work?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="2566" rel="nofollow" href="https://www.academia.edu/Documents/in/Child_abuse_and_neglect">Child abuse and neglect</a>, <script data-card-contents-for-ri="2566" type="text/json">{"id":2566,"name":"Child abuse and neglect","url":"https://www.academia.edu/Documents/in/Child_abuse_and_neglect?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4545" rel="nofollow" href="https://www.academia.edu/Documents/in/Parenting">Parenting</a><script data-card-contents-for-ri="4545" type="text/json">{"id":4545,"name":"Parenting","url":"https://www.academia.edu/Documents/in/Parenting?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=11579814]'), work: {"id":11579814,"title":"Predicting child maltreatment in the first 4 years of life from characteristics assessed in the neonatal period","created_at":"2015-03-22T00:39:27.897-07:00","url":"https://www.academia.edu/11579814/Predicting_child_maltreatment_in_the_first_4_years_of_life_from_characteristics_assessed_in_the_neonatal_period?f_ri=620049","dom_id":"work_11579814","summary":"Objective: To examine the significance of neonatal risk factors from the individual, family, social, and parenting behavior domains of the ecological model of child maltreatment in predicting maltreatment reports in the first 4 years of life, and to examine the extent to which the interactions of life event stress and social support modify those risk factors. Method: Mothers of 708 predominantly at-risk infants were interviewed in their homes soon after their infants' discharge from the hospital. State child abuse and neglect central registry data were tracked every 6 months until the infants reached their fourth birthdays. Results: The incidence of maltreatment reports was higher in households where the mothers were depressed, complained of psychosomatic symptoms, had not graduated from high school, consumed alcohol, participated in public income support programs, cared for more than one dependent child, or were separated from their own mothers at age 14 years (p Ͻ .1). In interaction models including these seven predisposing variables, there were significant interactions (p Ͻ .01) between social support, as measured by the social well-being index after the birth of the index child, and depression, and between social well-being and stress, as measured by an increase in total life events. Conclusion: Some predisposing risk factors measured soon after birth continue to be significant predictors of child maltreatment reports through the fourth year of life. In general, families with low levels of social support had a higher risk of a maltreatment report. For families with lower levels of maternal depression and/or life event stress, low social support significantly increased the risk of a maltreatment report by as much as a factor of four.","downloadable_attachments":[{"id":46622130,"asset_id":11579814,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":28270985,"first_name":"Dorothy","last_name":"Browne","domain_name":"unc","page_name":"DorothyBrowne","display_name":"Dorothy Browne","profile_url":"https://unc.academia.edu/DorothyBrowne?f_ri=620049","photo":"https://0.academia-photos.com/28270985/15148590/15845579/s65_dorothy.browne.jpg"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=620049","nofollow":true},{"id":940,"name":"Social Work","url":"https://www.academia.edu/Documents/in/Social_Work?f_ri=620049","nofollow":true},{"id":2566,"name":"Child abuse and neglect","url":"https://www.academia.edu/Documents/in/Child_abuse_and_neglect?f_ri=620049","nofollow":true},{"id":4545,"name":"Parenting","url":"https://www.academia.edu/Documents/in/Parenting?f_ri=620049","nofollow":true},{"id":6666,"name":"Child Maltreatment","url":"https://www.academia.edu/Documents/in/Child_Maltreatment?f_ri=620049"},{"id":11015,"name":"Social Support","url":"https://www.academia.edu/Documents/in/Social_Support?f_ri=620049"},{"id":12159,"name":"Injury Prevention","url":"https://www.academia.edu/Documents/in/Injury_Prevention?f_ri=620049"},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=620049"},{"id":85930,"name":"High School","url":"https://www.academia.edu/Documents/in/High_School?f_ri=620049"},{"id":91079,"name":"Child Abuse","url":"https://www.academia.edu/Documents/in/Child_Abuse?f_ri=620049"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=620049"},{"id":174502,"name":"Incidence","url":"https://www.academia.edu/Documents/in/Incidence?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":253560,"name":"Newborn Infant","url":"https://www.academia.edu/Documents/in/Newborn_Infant?f_ri=620049"},{"id":297270,"name":"Ecological Model","url":"https://www.academia.edu/Documents/in/Ecological_Model?f_ri=620049"},{"id":510423,"name":"Income Support","url":"https://www.academia.edu/Documents/in/Income_Support?f_ri=620049"},{"id":608567,"name":"Interaction model","url":"https://www.academia.edu/Documents/in/Interaction_model?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":676456,"name":"Maternal Depression","url":"https://www.academia.edu/Documents/in/Maternal_Depression?f_ri=620049"},{"id":749302,"name":"Indexation","url":"https://www.academia.edu/Documents/in/Indexation?f_ri=620049"},{"id":1033015,"name":"Parent‐child Relations","url":"https://www.academia.edu/Documents/in/Parent_child_Relations?f_ri=620049"},{"id":1318932,"name":"Predictive value of tests","url":"https://www.academia.edu/Documents/in/Predictive_value_of_tests?f_ri=620049"},{"id":1414499,"name":"Life Change Events","url":"https://www.academia.edu/Documents/in/Life_Change_Events?f_ri=620049"},{"id":1558211,"name":"University of North Carolina","url":"https://www.academia.edu/Documents/in/University_of_North_Carolina?f_ri=620049"},{"id":1658786,"name":"Child Neglect","url":"https://www.academia.edu/Documents/in/Child_Neglect?f_ri=620049"},{"id":1780706,"name":"LIFE EVENT","url":"https://www.academia.edu/Documents/in/LIFE_EVENT?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_62737836" data-work_id="62737836" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/62737836/PET_CT_and_breast_cancer">PET/CT and breast cancer</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The use of general descriptive names, trademarks, etc. in this publication does not imply, even in the absence of a specifi c statement, that such names are exempt from the relevant protective laws and regulations and therefore free for... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_62737836" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The use of general descriptive names, trademarks, etc. in this publication does not imply, even in the absence of a specifi c statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every case the user must check such information by consulting the relevant literature.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/62737836" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="30c1873fd1bdf31834ce32c29dcc6089" rel="nofollow" data-download="{"attachment_id":75408775,"asset_id":62737836,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/75408775/download_file?st=MTczOTk5NjI5Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="209462481" href="https://unisr.academia.edu/mariapicchio">maria picchio</a><script data-card-contents-for-user="209462481" type="text/json">{"id":209462481,"first_name":"maria","last_name":"picchio","domain_name":"unisr","page_name":"mariapicchio","display_name":"maria picchio","profile_url":"https://unisr.academia.edu/mariapicchio?f_ri=620049","photo":"https://0.academia-photos.com/209462481/69272897/57669330/s65_maria.picchio.jpg"}</script></span></span></li><li class="js-paper-rank-work_62737836 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="62737836"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 62737836, container: ".js-paper-rank-work_62737836", }); });</script></li><li class="js-percentile-work_62737836 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 62737836; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_62737836"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_62737836 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="62737836"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 62737836; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=62737836]").text(description); $(".js-view-count-work_62737836").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_62737836").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="62737836"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">18</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="1648" rel="nofollow" href="https://www.academia.edu/Documents/in/Computed_Tomography">Computed Tomography</a>, <script data-card-contents-for-ri="1648" type="text/json">{"id":1648,"name":"Computed Tomography","url":"https://www.academia.edu/Documents/in/Computed_Tomography?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6802" rel="nofollow" href="https://www.academia.edu/Documents/in/Breast_Cancer">Breast Cancer</a>, <script data-card-contents-for-ri="6802" type="text/json">{"id":6802,"name":"Breast Cancer","url":"https://www.academia.edu/Documents/in/Breast_Cancer?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="16664" rel="nofollow" href="https://www.academia.edu/Documents/in/Risk_assessment">Risk assessment</a>, <script data-card-contents-for-ri="16664" type="text/json">{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="23518" rel="nofollow" href="https://www.academia.edu/Documents/in/Positron_Emission_Tomography">Positron Emission Tomography</a><script data-card-contents-for-ri="23518" type="text/json">{"id":23518,"name":"Positron Emission Tomography","url":"https://www.academia.edu/Documents/in/Positron_Emission_Tomography?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=62737836]'), work: {"id":62737836,"title":"PET/CT and breast cancer","created_at":"2021-11-30T01:59:23.765-08:00","url":"https://www.academia.edu/62737836/PET_CT_and_breast_cancer?f_ri=620049","dom_id":"work_62737836","summary":"The use of general descriptive names, trademarks, etc. in this publication does not imply, even in the absence of a specifi c statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every case the user must check such information by consulting the relevant literature.","downloadable_attachments":[{"id":75408775,"asset_id":62737836,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":209462481,"first_name":"maria","last_name":"picchio","domain_name":"unisr","page_name":"mariapicchio","display_name":"maria picchio","profile_url":"https://unisr.academia.edu/mariapicchio?f_ri=620049","photo":"https://0.academia-photos.com/209462481/69272897/57669330/s65_maria.picchio.jpg"}],"research_interests":[{"id":1648,"name":"Computed Tomography","url":"https://www.academia.edu/Documents/in/Computed_Tomography?f_ri=620049","nofollow":true},{"id":6802,"name":"Breast Cancer","url":"https://www.academia.edu/Documents/in/Breast_Cancer?f_ri=620049","nofollow":true},{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=620049","nofollow":true},{"id":23518,"name":"Positron Emission Tomography","url":"https://www.academia.edu/Documents/in/Positron_Emission_Tomography?f_ri=620049","nofollow":true},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=620049"},{"id":279027,"name":"European","url":"https://www.academia.edu/Documents/in/European?f_ri=620049"},{"id":489727,"name":"Prognosis","url":"https://www.academia.edu/Documents/in/Prognosis?f_ri=620049"},{"id":532278,"name":"Cancer Patient","url":"https://www.academia.edu/Documents/in/Cancer_Patient?f_ri=620049"},{"id":549280,"name":"Reproducibility of Results","url":"https://www.academia.edu/Documents/in/Reproducibility_of_Results?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":622589,"name":"Risk Assessment","url":"https://www.academia.edu/Documents/in/Risk_Assessment-2?f_ri=620049"},{"id":784086,"name":"Radiopharmaceuticals","url":"https://www.academia.edu/Documents/in/Radiopharmaceuticals?f_ri=620049"},{"id":901876,"name":"Sensitivity and Specificity","url":"https://www.academia.edu/Documents/in/Sensitivity_and_Specificity?f_ri=620049"},{"id":1779488,"name":"Breast Cancer Diagnosis","url":"https://www.academia.edu/Documents/in/Breast_Cancer_Diagnosis?f_ri=620049"},{"id":2439414,"name":"Magnetic resonance image","url":"https://www.academia.edu/Documents/in/Magnetic_resonance_image?f_ri=620049"},{"id":2463778,"name":"Clinical Trials as Topic","url":"https://www.academia.edu/Documents/in/Clinical_Trials_as_Topic?f_ri=620049"},{"id":2847999,"name":"Breast Neoplasms","url":"https://www.academia.edu/Documents/in/Breast_Neoplasms?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_27371495 coauthored" data-work_id="27371495" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/27371495/Presentation_and_Management_of_Splenic_Injury_After_Colonoscopy">Presentation and Management of Splenic Injury After Colonoscopy</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">This study reviewed all single experience of splenic injuries after colonoscopy in the last 40 years to define the possible risk factors and the management of this complication. A MEDLINE and a PubMed search was undertaken to identify... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_27371495" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">This study reviewed all single experience of splenic injuries after colonoscopy in the last 40 years to define the possible risk factors and the management of this complication. A MEDLINE and a PubMed search was undertaken to identify articles in English, French, Spanish, and Italian from 1974 to 2012 using the key words: "splenic injury," "splenic rupture," and "colonoscopy." Data were analyzed using descriptive statistic. A total of 103 cases have been described in 75 reports. The majority of the patients were women (71.56%) and 6.85% underwent previous pelvic surgery. The mean age was 63 years (range, 29 to 90 y). About 61 of the 103 studies (59.2%) reported the presence or the absence of previous abdominal surgery and within these, only 31 of 61 patients (50.82%) underwent previous abdominal surgery. In this review, over half of the patients with splenic injury underwent colonoscopy for routine surveillance (62.75%), and only one third of the splenic injures were associated with biopsy or polypectomy. The majority of patients (78.57%) developed symptoms within the first 24 hours after colonoscopy and in a minority of cases (21.43%), there was a delayed presentation 24 hours after colonoscopy. Computed tomography was used as the primary modality to make the diagnosis in 69 of 98 cases (70.41%) and as a confirmatory test in many additional cases. Twenty-six of 102 patients (25.49%) were treated by conservative methods, whereas the majority of patients (69.61%) underwent splenectomy as a definitive treatment. Because of possible medicolegal implications, the endoscopists should consider mentioning splenic injury on the consent form of colonoscopy after bowel perforation and bleeding, particularly in higher risk patients.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/27371495" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="8d27740ccfd2ab9b46a06a0764f167b7" rel="nofollow" data-download="{"attachment_id":47625844,"asset_id":27371495,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/47625844/download_file?st=MTczOTk5NjI5Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="51489459" href="https://independent.academia.edu/FrancescoCard%C3%AC">Francesco Cardì</a><script data-card-contents-for-user="51489459" type="text/json">{"id":51489459,"first_name":"Francesco","last_name":"Cardì","domain_name":"independent","page_name":"FrancescoCardì","display_name":"Francesco Cardì","profile_url":"https://independent.academia.edu/FrancescoCard%C3%AC?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-27371495">+1</span><div class="hidden js-additional-users-27371495"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/PiccoloGaetano">Gaetano Piccolo</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-27371495'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-27371495').html(); 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A MEDLINE and a PubMed search was undertaken to identify articles in English, French, Spanish, and Italian from 1974 to 2012 using the key words: \"splenic injury,\" \"splenic rupture,\" and \"colonoscopy.\" Data were analyzed using descriptive statistic. A total of 103 cases have been described in 75 reports. The majority of the patients were women (71.56%) and 6.85% underwent previous pelvic surgery. The mean age was 63 years (range, 29 to 90 y). About 61 of the 103 studies (59.2%) reported the presence or the absence of previous abdominal surgery and within these, only 31 of 61 patients (50.82%) underwent previous abdominal surgery. In this review, over half of the patients with splenic injury underwent colonoscopy for routine surveillance (62.75%), and only one third of the splenic injures were associated with biopsy or polypectomy. The majority of patients (78.57%) developed symptoms within the first 24 hours after colonoscopy and in a minority of cases (21.43%), there was a delayed presentation 24 hours after colonoscopy. Computed tomography was used as the primary modality to make the diagnosis in 69 of 98 cases (70.41%) and as a confirmatory test in many additional cases. Twenty-six of 102 patients (25.49%) were treated by conservative methods, whereas the majority of patients (69.61%) underwent splenectomy as a definitive treatment. Because of possible medicolegal implications, the endoscopists should consider mentioning splenic injury on the consent form of colonoscopy after bowel perforation and bleeding, particularly in higher risk patients.","downloadable_attachments":[{"id":47625844,"asset_id":27371495,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":51489459,"first_name":"Francesco","last_name":"Cardì","domain_name":"independent","page_name":"FrancescoCardì","display_name":"Francesco Cardì","profile_url":"https://independent.academia.edu/FrancescoCard%C3%AC?f_ri=620049","photo":"/images/s65_no_pic.png"},{"id":51602444,"first_name":"Gaetano","last_name":"Piccolo","domain_name":"independent","page_name":"PiccoloGaetano","display_name":"Gaetano 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rupture","url":"https://www.academia.edu/Documents/in/splenic_rupture?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_17935743" data-work_id="17935743" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/17935743/Accuracy_of_cystoscopy_in_the_diagnosis_of_ureteral_injury_in_benign_gynecologic_surgery">Accuracy of cystoscopy in the diagnosis of ureteral injury in benign gynecologic surgery</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/17935743" data-share-source="work_strip" 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href="https://www.academia.edu/12951217/Choice_of_a_mechanical_valve_or_a_bioprosthesis_for_AVR_does_CABG_matter">Choice of a mechanical valve or a bioprosthesis for AVR: does CABG matter?</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/12951217" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="928274a25d15aa7f30f23648e576a3f1" rel="nofollow" data-download="{"attachment_id":45827582,"asset_id":12951217,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm 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Steyerberg","profile_url":"https://leidenuni.academia.edu/EwoutSteyerberg?f_ri=620049","photo":"https://0.academia-photos.com/32137255/18807008/18766876/s65_ewout.steyerberg.jpg"}</script></span></span></li><li class="js-paper-rank-work_12951217 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="12951217"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 12951217, container: ".js-paper-rank-work_12951217", }); });</script></li><li class="js-percentile-work_12951217 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 12951217; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container 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style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="12951217"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">12</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="12426" rel="nofollow" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a>, <script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="27521" rel="nofollow" href="https://www.academia.edu/Documents/in/Stents">Stents</a>, <script data-card-contents-for-ri="27521" type="text/json">{"id":27521,"name":"Stents","url":"https://www.academia.edu/Documents/in/Stents?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="172892" rel="nofollow" href="https://www.academia.edu/Documents/in/Life_Expectancy">Life Expectancy</a><script data-card-contents-for-ri="172892" type="text/json">{"id":172892,"name":"Life Expectancy","url":"https://www.academia.edu/Documents/in/Life_Expectancy?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=12951217]'), work: {"id":12951217,"title":"Choice of a mechanical valve or a bioprosthesis for AVR: does CABG matter?","created_at":"2015-06-12T11:47:42.347-07:00","url":"https://www.academia.edu/12951217/Choice_of_a_mechanical_valve_or_a_bioprosthesis_for_AVR_does_CABG_matter?f_ri=620049","dom_id":"work_12951217","summary":null,"downloadable_attachments":[{"id":45827582,"asset_id":12951217,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32137255,"first_name":"Ewout","last_name":"Steyerberg","domain_name":"leidenuni","page_name":"EwoutSteyerberg","display_name":"Ewout Steyerberg","profile_url":"https://leidenuni.academia.edu/EwoutSteyerberg?f_ri=620049","photo":"https://0.academia-photos.com/32137255/18807008/18766876/s65_ewout.steyerberg.jpg"}],"research_interests":[{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=620049","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=620049","nofollow":true},{"id":27521,"name":"Stents","url":"https://www.academia.edu/Documents/in/Stents?f_ri=620049","nofollow":true},{"id":172892,"name":"Life Expectancy","url":"https://www.academia.edu/Documents/in/Life_Expectancy?f_ri=620049","nofollow":true},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":218206,"name":"Meta Analysis","url":"https://www.academia.edu/Documents/in/Meta_Analysis?f_ri=620049"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=620049"},{"id":521483,"name":"Large Data Sets","url":"https://www.academia.edu/Documents/in/Large_Data_Sets?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":715808,"name":"prosthesis Design","url":"https://www.academia.edu/Documents/in/prosthesis_Design?f_ri=620049"},{"id":906219,"name":"Coronary artery bypass surgery","url":"https://www.academia.edu/Documents/in/Coronary_artery_bypass_surgery?f_ri=620049"},{"id":1264978,"name":"Aortic Valve","url":"https://www.academia.edu/Documents/in/Aortic_Valve?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_14281349" data-work_id="14281349" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/14281349/Falls_Assessment_Clinical_Trial_FACT_design_interventions_recruitment_strategies_and_participant_characteristics">Falls Assessment Clinical Trial (FACT): design, interventions, recruitment strategies and participant characteristics</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Background: Guidelines recommend multifactorial intervention programmes to prevent falls in older adults but there are few randomised controlled trials in a real life health care setting. We describe the rationale, intervention, study... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_14281349" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Background: Guidelines recommend multifactorial intervention programmes to prevent falls in older adults but there are few randomised controlled trials in a real life health care setting. We describe the rationale, intervention, study design, recruitment strategies and baseline characteristics of participants in a randomised controlled trial of a multifactorial falls prevention programme in primary health care.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/14281349" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="bdfc50b7177eb39a35b2326570c397e4" rel="nofollow" data-download="{"attachment_id":44359499,"asset_id":14281349,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44359499/download_file?st=MTczOTk5NjI5Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33246179" href="https://independent.academia.edu/EileenMcKinlay">Eileen McKinlay</a><script data-card-contents-for-user="33246179" type="text/json">{"id":33246179,"first_name":"Eileen","last_name":"McKinlay","domain_name":"independent","page_name":"EileenMcKinlay","display_name":"Eileen McKinlay","profile_url":"https://independent.academia.edu/EileenMcKinlay?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_14281349 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="14281349"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 14281349, container: ".js-paper-rank-work_14281349", }); });</script></li><li class="js-percentile-work_14281349 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14281349; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_14281349"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_14281349 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="14281349"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14281349; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14281349]").text(description); $(".js-view-count-work_14281349").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_14281349").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="14281349"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">21</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="633" rel="nofollow" href="https://www.academia.edu/Documents/in/Primary_Care">Primary Care</a>, <script data-card-contents-for-ri="633" type="text/json">{"id":633,"name":"Primary Care","url":"https://www.academia.edu/Documents/in/Primary_Care?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="940" rel="nofollow" href="https://www.academia.edu/Documents/in/Social_Work">Social Work</a>, <script data-card-contents-for-ri="940" type="text/json">{"id":940,"name":"Social Work","url":"https://www.academia.edu/Documents/in/Social_Work?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="2974" rel="nofollow" href="https://www.academia.edu/Documents/in/Primary_Health_Care">Primary Health Care</a>, <script data-card-contents-for-ri="2974" type="text/json">{"id":2974,"name":"Primary Health Care","url":"https://www.academia.edu/Documents/in/Primary_Health_Care?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4441" rel="nofollow" href="https://www.academia.edu/Documents/in/Health_Care">Health Care</a><script data-card-contents-for-ri="4441" type="text/json">{"id":4441,"name":"Health Care","url":"https://www.academia.edu/Documents/in/Health_Care?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=14281349]'), work: {"id":14281349,"title":"Falls Assessment Clinical Trial (FACT): design, interventions, recruitment strategies and participant characteristics","created_at":"2015-07-22T01:07:57.327-07:00","url":"https://www.academia.edu/14281349/Falls_Assessment_Clinical_Trial_FACT_design_interventions_recruitment_strategies_and_participant_characteristics?f_ri=620049","dom_id":"work_14281349","summary":"Background: Guidelines recommend multifactorial intervention programmes to prevent falls in older adults but there are few randomised controlled trials in a real life health care setting. We describe the rationale, intervention, study design, recruitment strategies and baseline characteristics of participants in a randomised controlled trial of a multifactorial falls prevention programme in primary health care.","downloadable_attachments":[{"id":44359499,"asset_id":14281349,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33246179,"first_name":"Eileen","last_name":"McKinlay","domain_name":"independent","page_name":"EileenMcKinlay","display_name":"Eileen McKinlay","profile_url":"https://independent.academia.edu/EileenMcKinlay?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":633,"name":"Primary Care","url":"https://www.academia.edu/Documents/in/Primary_Care?f_ri=620049","nofollow":true},{"id":940,"name":"Social Work","url":"https://www.academia.edu/Documents/in/Social_Work?f_ri=620049","nofollow":true},{"id":2974,"name":"Primary Health Care","url":"https://www.academia.edu/Documents/in/Primary_Health_Care?f_ri=620049","nofollow":true},{"id":4441,"name":"Health Care","url":"https://www.academia.edu/Documents/in/Health_Care?f_ri=620049","nofollow":true},{"id":4531,"name":"Clinical Trial","url":"https://www.academia.edu/Documents/in/Clinical_Trial?f_ri=620049"},{"id":7470,"name":"Quality of life","url":"https://www.academia.edu/Documents/in/Quality_of_life?f_ri=620049"},{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=620049"},{"id":25469,"name":"Family Practice","url":"https://www.academia.edu/Documents/in/Family_Practice?f_ri=620049"},{"id":116108,"name":"New Zealand","url":"https://www.academia.edu/Documents/in/New_Zealand?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":194055,"name":"Randomised Controlled Trial","url":"https://www.academia.edu/Documents/in/Randomised_Controlled_Trial?f_ri=620049"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=620049"},{"id":327850,"name":"Questionnaires","url":"https://www.academia.edu/Documents/in/Questionnaires?f_ri=620049"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=620049"},{"id":584602,"name":"Geriatric Assessment","url":"https://www.academia.edu/Documents/in/Geriatric_Assessment?f_ri=620049"},{"id":613467,"name":"Intervention study","url":"https://www.academia.edu/Documents/in/Intervention_study?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":622589,"name":"Risk Assessment","url":"https://www.academia.edu/Documents/in/Risk_Assessment-2?f_ri=620049"},{"id":784431,"name":"Nursing Assessment","url":"https://www.academia.edu/Documents/in/Nursing_Assessment?f_ri=620049"},{"id":806178,"name":"Older Adult","url":"https://www.academia.edu/Documents/in/Older_Adult?f_ri=620049"},{"id":2195821,"name":"Activity of Daily Living","url":"https://www.academia.edu/Documents/in/Activity_of_Daily_Living?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_14850025" data-work_id="14850025" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/14850025/Plasma_free_choline_betaine_and_cognitive_performance_the_Hordaland_Health_Study">Plasma free choline, betaine and cognitive performance: the Hordaland Health Study</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Choline and betaine are nutrients involved in one-carbon metabolism. Choline is essential for neurodevelopment and brain function. We studied the associations between cognitive function and plasma concentrations of free choline and... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_14850025" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Choline and betaine are nutrients involved in one-carbon metabolism. Choline is essential for neurodevelopment and brain function. We studied the associations between cognitive function and plasma concentrations of free choline and betaine. In a cross-sectional study, 2195 subjects (55 % women), aged 70-74 years, underwent extensive cognitive testing including the Kendrick Object Learning Test (KOLT), Trail Making Test (part A, TMT-A), modified versions of the Digit Symbol Test (m-DST), Block Design (m-BD), Mini-Mental State Examination (m-MMSE) and Controlled Oral Word Association Test (COWAT). Compared with low concentrations, high choline (.8·4 mmol/l) was associated with better test scores in the TMT-A (56·0 v. 61·5, P¼ 0·004), m-DST (10·5 v. 9·8, P¼ 0·005) and m-MMSE (11·5 v. 11·4, P¼ 0·01). A generalised additive regression model showed a positive dose -response relationship between the m-MMSE and choline (P¼0·012 from a corresponding linear regression model). Betaine was associated with the KOLT, TMT-A and COWAT, but after adjustments for potential confounders, the associations lost significance. Risk ratios (RR) for poor test performance roughly tripled when low choline was combined with either low plasma vitamin B 12 (# 257 pmol/l) concentrations (RR KOLT ¼ 2·6, 95 % CI 1·1, 6·1; RR m-MMSE ¼ 2·7, 95 % CI 1·1, 6·6; RR COWAT ¼ 3·1, 95 % CI 1·4, 7·2) or high methylmalonic acid (MMA) ($3·95 mmol/l) concentrations (RR m-BD ¼ 2·8, 95 % CI 1·3, 6·1). Low betaine (# 31·1 mmol/l) combined with high MMA was associated with elevated RR on KOLT (RR KOLT ¼ 2·5, 95 % CI 1·0, 6·2). Low plasma free choline concentrations are associated with poor cognitive performance. There were significant interactions between low choline or betaine and low vitamin B 12 or high MMA on cognitive performance.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/14850025" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="d23ce6fac5d281caf5991600b2e42ebe" rel="nofollow" data-download="{"attachment_id":43844826,"asset_id":14850025,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/43844826/download_file?st=MTczOTk5NjI5Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33816925" href="https://uib.academia.edu/IngvarBjelland">Ingvar Bjelland</a><script data-card-contents-for-user="33816925" type="text/json">{"id":33816925,"first_name":"Ingvar","last_name":"Bjelland","domain_name":"uib","page_name":"IngvarBjelland","display_name":"Ingvar Bjelland","profile_url":"https://uib.academia.edu/IngvarBjelland?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_14850025 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="14850025"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 14850025, container: ".js-paper-rank-work_14850025", }); });</script></li><li class="js-percentile-work_14850025 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14850025; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_14850025"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_14850025 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="14850025"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14850025; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14850025]").text(description); $(".js-view-count-work_14850025").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_14850025").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="14850025"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">18</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="591" rel="nofollow" href="https://www.academia.edu/Documents/in/Nutrition_and_Dietetics">Nutrition and Dietetics</a>, <script data-card-contents-for-ri="591" type="text/json">{"id":591,"name":"Nutrition and Dietetics","url":"https://www.academia.edu/Documents/in/Nutrition_and_Dietetics?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6791" rel="nofollow" href="https://www.academia.edu/Documents/in/Aging">Aging</a>, <script data-card-contents-for-ri="6791" type="text/json">{"id":6791,"name":"Aging","url":"https://www.academia.edu/Documents/in/Aging?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="8971" rel="nofollow" href="https://www.academia.edu/Documents/in/Mild_Cognitive_Impairment">Mild Cognitive Impairment</a>, <script data-card-contents-for-ri="8971" type="text/json">{"id":8971,"name":"Mild Cognitive Impairment","url":"https://www.academia.edu/Documents/in/Mild_Cognitive_Impairment?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="9478" rel="nofollow" href="https://www.academia.edu/Documents/in/Diet">Diet</a><script data-card-contents-for-ri="9478" type="text/json">{"id":9478,"name":"Diet","url":"https://www.academia.edu/Documents/in/Diet?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=14850025]'), work: {"id":14850025,"title":"Plasma free choline, betaine and cognitive performance: the Hordaland Health Study","created_at":"2015-08-11T07:03:32.069-07:00","url":"https://www.academia.edu/14850025/Plasma_free_choline_betaine_and_cognitive_performance_the_Hordaland_Health_Study?f_ri=620049","dom_id":"work_14850025","summary":"Choline and betaine are nutrients involved in one-carbon metabolism. Choline is essential for neurodevelopment and brain function. We studied the associations between cognitive function and plasma concentrations of free choline and betaine. In a cross-sectional study, 2195 subjects (55 % women), aged 70-74 years, underwent extensive cognitive testing including the Kendrick Object Learning Test (KOLT), Trail Making Test (part A, TMT-A), modified versions of the Digit Symbol Test (m-DST), Block Design (m-BD), Mini-Mental State Examination (m-MMSE) and Controlled Oral Word Association Test (COWAT). Compared with low concentrations, high choline (.8·4 mmol/l) was associated with better test scores in the TMT-A (56·0 v. 61·5, P¼ 0·004), m-DST (10·5 v. 9·8, P¼ 0·005) and m-MMSE (11·5 v. 11·4, P¼ 0·01). A generalised additive regression model showed a positive dose -response relationship between the m-MMSE and choline (P¼0·012 from a corresponding linear regression model). Betaine was associated with the KOLT, TMT-A and COWAT, but after adjustments for potential confounders, the associations lost significance. Risk ratios (RR) for poor test performance roughly tripled when low choline was combined with either low plasma vitamin B 12 (# 257 pmol/l) concentrations (RR KOLT ¼ 2·6, 95 % CI 1·1, 6·1; RR m-MMSE ¼ 2·7, 95 % CI 1·1, 6·6; RR COWAT ¼ 3·1, 95 % CI 1·4, 7·2) or high methylmalonic acid (MMA) ($3·95 mmol/l) concentrations (RR m-BD ¼ 2·8, 95 % CI 1·3, 6·1). Low betaine (# 31·1 mmol/l) combined with high MMA was associated with elevated RR on KOLT (RR KOLT ¼ 2·5, 95 % CI 1·0, 6·2). Low plasma free choline concentrations are associated with poor cognitive performance. There were significant interactions between low choline or betaine and low vitamin B 12 or high MMA on cognitive performance.","downloadable_attachments":[{"id":43844826,"asset_id":14850025,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33816925,"first_name":"Ingvar","last_name":"Bjelland","domain_name":"uib","page_name":"IngvarBjelland","display_name":"Ingvar Bjelland","profile_url":"https://uib.academia.edu/IngvarBjelland?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":591,"name":"Nutrition and Dietetics","url":"https://www.academia.edu/Documents/in/Nutrition_and_Dietetics?f_ri=620049","nofollow":true},{"id":6791,"name":"Aging","url":"https://www.academia.edu/Documents/in/Aging?f_ri=620049","nofollow":true},{"id":8971,"name":"Mild Cognitive Impairment","url":"https://www.academia.edu/Documents/in/Mild_Cognitive_Impairment?f_ri=620049","nofollow":true},{"id":9478,"name":"Diet","url":"https://www.academia.edu/Documents/in/Diet?f_ri=620049","nofollow":true},{"id":29980,"name":"Animal Production","url":"https://www.academia.edu/Documents/in/Animal_Production?f_ri=620049"},{"id":51645,"name":"Norway","url":"https://www.academia.edu/Documents/in/Norway?f_ri=620049"},{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=620049"},{"id":568482,"name":"Biological markers","url":"https://www.academia.edu/Documents/in/Biological_markers?f_ri=620049"},{"id":573653,"name":"Food Sciences","url":"https://www.academia.edu/Documents/in/Food_Sciences?f_ri=620049"},{"id":584602,"name":"Geriatric Assessment","url":"https://www.academia.edu/Documents/in/Geriatric_Assessment?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":990296,"name":"Choline","url":"https://www.academia.edu/Documents/in/Choline?f_ri=620049"},{"id":1034181,"name":"Cross Sectional Studies","url":"https://www.academia.edu/Documents/in/Cross_Sectional_Studies?f_ri=620049"},{"id":1716295,"name":"vitamin B deficiency","url":"https://www.academia.edu/Documents/in/vitamin_B_deficiency?f_ri=620049"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=620049"},{"id":2190576,"name":"Betaine","url":"https://www.academia.edu/Documents/in/Betaine?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_6408155" data-work_id="6408155" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" rel="nofollow" href="https://www.academia.edu/6408155/Risk_factors_for_mortality_after_the_Norwood_procedure">Risk factors for mortality after the Norwood procedure</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objectives: Recent studies have suggested that survival following the Norwood procedure is influenced by anatomy and is worse for patients with hypoplastic left heart syndrome (HLHS), particularly aortic atresia (AA), as compared to other... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_6408155" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objectives: Recent studies have suggested that survival following the Norwood procedure is influenced by anatomy and is worse for patients with hypoplastic left heart syndrome (HLHS), particularly aortic atresia (AA), as compared to other forms of functional single ventricle and systemic outflow tract obstruction. The current study was undertaken to evaluate our recent experience with the Norwood procedure and to evaluate potential predictors of operative and 1-year mortality. Methods: A retrospective study of risk factors for operative and 1-year mortality in 158 patients undergoing the Norwood procedure between January 1, 1998 and June 30, 2001. Results: HLHS was present in 102 patients (70 with AA) and other forms of functional single ventricle with systemic outflow tract obstruction in the remaining 56. Operative survival was 77% (122/158), 78% for patients with HLHS and 75% for patients with other diagnoses. Multivariable analysis identified birth weight (odds ratio (OR) 0.18/kg, 95% confidence limit (CL) 0.08-0.42, P , 0:001), associated cardiac anomalies (OR 4.45, 95% CL 1.50-13.2, P ¼ 0:001), total support time (OR 1.02/min, 95% CL 1.01-1.03, P ¼ 0:004), and extracorporeal membrane oxygenation (ECMO) or ventricular assist device (VAD) support (OR 17.8, 95% CL 4.40-71.0, P , 0:001) as predictors of operative mortality. The anatomic diagnosis (HLHS versus non-HLHS) was not a predictor of mortality, P ¼ 0:6). The Kaplan-Meier survival estimate at 1 year was 66% (95% CL 58-73%) and was not different for patients with HLHS compared to non-HLHS, P ¼ 0:5. For patients who have survived the Norwood procedure, survival to 1 year was 86% (95% CL 78-91%). Presence of an extra-cardiac anomaly or genetic syndrome (OR 2.70, 95% CL 0.98-7.41%, P ¼ 0:05) and presence of an additional cardiac defect (OR 3.99, 95% CL 1.67-9.57, P ¼ 0:002) were predictors of worse survival in the first year of life. Conclusions: The Norwood procedure is currently being applied to a heterogeneous group of patients. Operative and 1-year survival are equivalent for patients with HLHS and those with other cardiac defects. The presence of additional cardiac or extra-cardiac anomalies are predictors of poor outcome. q</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/6408155" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="6f2dc6a78aa1cd1d929795280954027b" rel="nofollow" data-download="{"attachment_id":48880517,"asset_id":6408155,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48880517/download_file?st=MTczOTk5NjI5Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="10077507" rel="nofollow" href="https://azburncenter.academia.edu/MitchellCohen">Mitchell Cohen</a><script data-card-contents-for-user="10077507" type="text/json">{"id":10077507,"first_name":"Mitchell","last_name":"Cohen","domain_name":"azburncenter","page_name":"MitchellCohen","display_name":"Mitchell Cohen","profile_url":"https://azburncenter.academia.edu/MitchellCohen?f_ri=620049","photo":"https://0.academia-photos.com/10077507/3119553/3672322/s65_mitchell.cohen.png"}</script></span></span></li><li class="js-paper-rank-work_6408155 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="6408155"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 6408155, container: ".js-paper-rank-work_6408155", }); 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$(".js-view-count[data-work-id=6408155]").text(description); $(".js-view-count-work_6408155").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_6408155").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="6408155"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">18</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="156" rel="nofollow" href="https://www.academia.edu/Documents/in/Genetics">Genetics</a>, <script data-card-contents-for-ri="156" type="text/json">{"id":156,"name":"Genetics","url":"https://www.academia.edu/Documents/in/Genetics?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="10610" rel="nofollow" href="https://www.academia.edu/Documents/in/Survival_Analysis">Survival Analysis</a>, <script data-card-contents-for-ri="10610" type="text/json">{"id":10610,"name":"Survival Analysis","url":"https://www.academia.edu/Documents/in/Survival_Analysis?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="41482" rel="nofollow" href="https://www.academia.edu/Documents/in/Multivariate_Analysis">Multivariate Analysis</a>, <script data-card-contents-for-ri="41482" type="text/json">{"id":41482,"name":"Multivariate Analysis","url":"https://www.academia.edu/Documents/in/Multivariate_Analysis?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="47155" rel="nofollow" href="https://www.academia.edu/Documents/in/Birth_Weight">Birth Weight</a><script data-card-contents-for-ri="47155" type="text/json">{"id":47155,"name":"Birth Weight","url":"https://www.academia.edu/Documents/in/Birth_Weight?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=6408155]'), work: {"id":6408155,"title":"Risk factors for mortality after the Norwood procedure","created_at":"2014-03-14T00:18:31.042-07:00","url":"https://www.academia.edu/6408155/Risk_factors_for_mortality_after_the_Norwood_procedure?f_ri=620049","dom_id":"work_6408155","summary":"Objectives: Recent studies have suggested that survival following the Norwood procedure is influenced by anatomy and is worse for patients with hypoplastic left heart syndrome (HLHS), particularly aortic atresia (AA), as compared to other forms of functional single ventricle and systemic outflow tract obstruction. The current study was undertaken to evaluate our recent experience with the Norwood procedure and to evaluate potential predictors of operative and 1-year mortality. Methods: A retrospective study of risk factors for operative and 1-year mortality in 158 patients undergoing the Norwood procedure between January 1, 1998 and June 30, 2001. Results: HLHS was present in 102 patients (70 with AA) and other forms of functional single ventricle with systemic outflow tract obstruction in the remaining 56. Operative survival was 77% (122/158), 78% for patients with HLHS and 75% for patients with other diagnoses. Multivariable analysis identified birth weight (odds ratio (OR) 0.18/kg, 95% confidence limit (CL) 0.08-0.42, P , 0:001), associated cardiac anomalies (OR 4.45, 95% CL 1.50-13.2, P ¼ 0:001), total support time (OR 1.02/min, 95% CL 1.01-1.03, P ¼ 0:004), and extracorporeal membrane oxygenation (ECMO) or ventricular assist device (VAD) support (OR 17.8, 95% CL 4.40-71.0, P , 0:001) as predictors of operative mortality. The anatomic diagnosis (HLHS versus non-HLHS) was not a predictor of mortality, P ¼ 0:6). The Kaplan-Meier survival estimate at 1 year was 66% (95% CL 58-73%) and was not different for patients with HLHS compared to non-HLHS, P ¼ 0:5. For patients who have survived the Norwood procedure, survival to 1 year was 86% (95% CL 78-91%). Presence of an extra-cardiac anomaly or genetic syndrome (OR 2.70, 95% CL 0.98-7.41%, P ¼ 0:05) and presence of an additional cardiac defect (OR 3.99, 95% CL 1.67-9.57, P ¼ 0:002) were predictors of worse survival in the first year of life. Conclusions: The Norwood procedure is currently being applied to a heterogeneous group of patients. Operative and 1-year survival are equivalent for patients with HLHS and those with other cardiac defects. The presence of additional cardiac or extra-cardiac anomalies are predictors of poor outcome. q","downloadable_attachments":[{"id":48880517,"asset_id":6408155,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":10077507,"first_name":"Mitchell","last_name":"Cohen","domain_name":"azburncenter","page_name":"MitchellCohen","display_name":"Mitchell Cohen","profile_url":"https://azburncenter.academia.edu/MitchellCohen?f_ri=620049","photo":"https://0.academia-photos.com/10077507/3119553/3672322/s65_mitchell.cohen.png"}],"research_interests":[{"id":156,"name":"Genetics","url":"https://www.academia.edu/Documents/in/Genetics?f_ri=620049","nofollow":true},{"id":10610,"name":"Survival Analysis","url":"https://www.academia.edu/Documents/in/Survival_Analysis?f_ri=620049","nofollow":true},{"id":41482,"name":"Multivariate Analysis","url":"https://www.academia.edu/Documents/in/Multivariate_Analysis?f_ri=620049","nofollow":true},{"id":47155,"name":"Birth Weight","url":"https://www.academia.edu/Documents/in/Birth_Weight?f_ri=620049","nofollow":true},{"id":88113,"name":"Left Ventricular Assist Device","url":"https://www.academia.edu/Documents/in/Left_Ventricular_Assist_Device?f_ri=620049"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":253560,"name":"Newborn Infant","url":"https://www.academia.edu/Documents/in/Newborn_Infant?f_ri=620049"},{"id":279027,"name":"European","url":"https://www.academia.edu/Documents/in/European?f_ri=620049"},{"id":372494,"name":"Kaplan-Meier","url":"https://www.academia.edu/Documents/in/Kaplan-Meier?f_ri=620049"},{"id":442734,"name":"First Year","url":"https://www.academia.edu/Documents/in/First_Year?f_ri=620049"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":990198,"name":"Retrospective Study","url":"https://www.academia.edu/Documents/in/Retrospective_Study?f_ri=620049"},{"id":1228884,"name":"Confidence Limit","url":"https://www.academia.edu/Documents/in/Confidence_Limit?f_ri=620049"},{"id":1294607,"name":"Logistic Models","url":"https://www.academia.edu/Documents/in/Logistic_Models?f_ri=620049"},{"id":1588897,"name":"Hypoplastic Left Heart Syndrome","url":"https://www.academia.edu/Documents/in/Hypoplastic_Left_Heart_Syndrome?f_ri=620049"},{"id":2328629,"name":"Extracorporeal Membrane Oxygenation","url":"https://www.academia.edu/Documents/in/Extracorporeal_Membrane_Oxygenation?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_22286369" data-work_id="22286369" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/22286369/Childrens_mental_health_The_gap_between_what_we_know_and_what_we_do">Children's mental health: The gap between what we know and what we do</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">... This gap between what we know should be provided and what is provided is the result of a poorly structured health care financing system ... applied in a host of other settings where children are served, including schools, health... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_22286369" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">... This gap between what we know should be provided and what is provided is the result of a poorly structured health care financing system ... applied in a host of other settings where children are served, including schools, health clin-ics, child welfare agencies, and juvenile courts. ...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/22286369" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="f8691c64584459d78068d200c0123cbe" rel="nofollow" data-download="{"attachment_id":54621870,"asset_id":22286369,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/54621870/download_file?st=MTczOTk5NjI5Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="30113118" href="https://independent.academia.edu/LeonardSaxe">Leonard Saxe</a><script data-card-contents-for-user="30113118" type="text/json">{"id":30113118,"first_name":"Leonard","last_name":"Saxe","domain_name":"independent","page_name":"LeonardSaxe","display_name":"Leonard Saxe","profile_url":"https://independent.academia.edu/LeonardSaxe?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_22286369 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="22286369"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 22286369, container: ".js-paper-rank-work_22286369", }); });</script></li><li class="js-percentile-work_22286369 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 22286369; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_22286369"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_22286369 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="22286369"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 22286369; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=22286369]").text(description); $(".js-view-count-work_22286369").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_22286369").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="22286369"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">13</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="237" rel="nofollow" href="https://www.academia.edu/Documents/in/Cognitive_Science">Cognitive Science</a>, <script data-card-contents-for-ri="237" type="text/json">{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="2827" rel="nofollow" href="https://www.academia.edu/Documents/in/Mental_Health">Mental Health</a>, <script data-card-contents-for-ri="2827" type="text/json">{"id":2827,"name":"Mental Health","url":"https://www.academia.edu/Documents/in/Mental_Health?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="64933" rel="nofollow" href="https://www.academia.edu/Documents/in/Child">Child</a><script data-card-contents-for-ri="64933" type="text/json">{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=22286369]'), work: {"id":22286369,"title":"Children's mental health: The gap between what we know and what we do","created_at":"2016-02-22T03:51:01.433-08:00","url":"https://www.academia.edu/22286369/Childrens_mental_health_The_gap_between_what_we_know_and_what_we_do?f_ri=620049","dom_id":"work_22286369","summary":"... This gap between what we know should be provided and what is provided is the result of a poorly structured health care financing system ... applied in a host of other settings where children are served, including schools, health clin-ics, child welfare agencies, and juvenile courts. ...","downloadable_attachments":[{"id":54621870,"asset_id":22286369,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":30113118,"first_name":"Leonard","last_name":"Saxe","domain_name":"independent","page_name":"LeonardSaxe","display_name":"Leonard Saxe","profile_url":"https://independent.academia.edu/LeonardSaxe?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=620049","nofollow":true},{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=620049","nofollow":true},{"id":2827,"name":"Mental Health","url":"https://www.academia.edu/Documents/in/Mental_Health?f_ri=620049","nofollow":true},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=620049","nofollow":true},{"id":95411,"name":"Personality Development","url":"https://www.academia.edu/Documents/in/Personality_Development?f_ri=620049"},{"id":102554,"name":"Health Care Financing","url":"https://www.academia.edu/Documents/in/Health_Care_Financing?f_ri=620049"},{"id":165565,"name":"Cost effectiveness","url":"https://www.academia.edu/Documents/in/Cost_effectiveness?f_ri=620049"},{"id":171144,"name":"Mental Disorders","url":"https://www.academia.edu/Documents/in/Mental_Disorders?f_ri=620049"},{"id":174464,"name":"Social Environment","url":"https://www.academia.edu/Documents/in/Social_Environment?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":387102,"name":"Environmental Conditions","url":"https://www.academia.edu/Documents/in/Environmental_Conditions?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":1723635,"name":"Public Policy","url":"https://www.academia.edu/Documents/in/Public_Policy?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_14264160" data-work_id="14264160" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/14264160/Delirium_A_disturbance_of_circadian_integrity">Delirium: A disturbance of circadian integrity?</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Delirium is a serious neuropsychiatric syndrome of acute onset that occurs in approximately one in five general hospital patients and is associated with serious adverse outcomes that include loss of adaptive function, persistent cognitive... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_14264160" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Delirium is a serious neuropsychiatric syndrome of acute onset that occurs in approximately one in five general hospital patients and is associated with serious adverse outcomes that include loss of adaptive function, persistent cognitive problems and increased mortality. Recent studies indicate a three-domain model for delirium that includes generalised cognitive impairment, disturbed executive cognition, and disruption of behaviours that are under circadian control such as sleep-wake cycle and motor activity levels. As a consequence, attention has focused upon the possible role of the circadian timing system (CTS) in the pathophysiology of delirium. We explored this possibility by reviewing evidence that (1) many symptoms that occur in delirium are influenced by circadian rhythms, (2) many features of recognised circadian rhythm disorders are similar to characteristic features of delirium, (3) common risk factors for delirium are known to disrupt circadian systems, (4) physiological disturbances of circadian systems have been noted in delirious patients, and (5) positive effects in the treatment of delirium have been demonstrated for melatonin and related agents that influence the circadian timing system. A programme of future studies that can help to clarify the relevance of circadian integrity to delirium is described. Such work can provide a better understanding of the pathophysiology of delirium while also identifying opportunities for more targeted therapeutic efforts.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/14264160" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="16363f323d956ea29d6d0d0b5ab3123c" rel="nofollow" data-download="{"attachment_id":44378905,"asset_id":14264160,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44378905/download_file?st=MTczOTk5NjI5Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33230232" href="https://independent.academia.edu/JamesFitzGerald12">James FitzGerald</a><script data-card-contents-for-user="33230232" type="text/json">{"id":33230232,"first_name":"James","last_name":"FitzGerald","domain_name":"independent","page_name":"JamesFitzGerald12","display_name":"James FitzGerald","profile_url":"https://independent.academia.edu/JamesFitzGerald12?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_14264160 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="14264160"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 14264160, container: ".js-paper-rank-work_14264160", }); });</script></li><li class="js-percentile-work_14264160 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14264160; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_14264160"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_14264160 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="14264160"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14264160; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14264160]").text(description); $(".js-view-count-work_14264160").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_14264160").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="14264160"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">7</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="48496" rel="nofollow" href="https://www.academia.edu/Documents/in/Delirium">Delirium</a>, <script data-card-contents-for-ri="48496" type="text/json">{"id":48496,"name":"Delirium","url":"https://www.academia.edu/Documents/in/Delirium?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="51570" rel="nofollow" href="https://www.academia.edu/Documents/in/Melatonin">Melatonin</a>, <script data-card-contents-for-ri="51570" type="text/json">{"id":51570,"name":"Melatonin","url":"https://www.academia.edu/Documents/in/Melatonin?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="106431" rel="nofollow" href="https://www.academia.edu/Documents/in/Sleep_disorders">Sleep disorders</a>, <script data-card-contents-for-ri="106431" type="text/json">{"id":106431,"name":"Sleep disorders","url":"https://www.academia.edu/Documents/in/Sleep_disorders?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="192721" rel="nofollow" href="https://www.academia.edu/Documents/in/Risk_factors">Risk factors</a><script data-card-contents-for-ri="192721" type="text/json">{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=14264160]'), work: {"id":14264160,"title":"Delirium: A disturbance of circadian integrity?","created_at":"2015-07-21T10:28:48.407-07:00","url":"https://www.academia.edu/14264160/Delirium_A_disturbance_of_circadian_integrity?f_ri=620049","dom_id":"work_14264160","summary":"Delirium is a serious neuropsychiatric syndrome of acute onset that occurs in approximately one in five general hospital patients and is associated with serious adverse outcomes that include loss of adaptive function, persistent cognitive problems and increased mortality. Recent studies indicate a three-domain model for delirium that includes generalised cognitive impairment, disturbed executive cognition, and disruption of behaviours that are under circadian control such as sleep-wake cycle and motor activity levels. As a consequence, attention has focused upon the possible role of the circadian timing system (CTS) in the pathophysiology of delirium. We explored this possibility by reviewing evidence that (1) many symptoms that occur in delirium are influenced by circadian rhythms, (2) many features of recognised circadian rhythm disorders are similar to characteristic features of delirium, (3) common risk factors for delirium are known to disrupt circadian systems, (4) physiological disturbances of circadian systems have been noted in delirious patients, and (5) positive effects in the treatment of delirium have been demonstrated for melatonin and related agents that influence the circadian timing system. A programme of future studies that can help to clarify the relevance of circadian integrity to delirium is described. Such work can provide a better understanding of the pathophysiology of delirium while also identifying opportunities for more targeted therapeutic efforts.","downloadable_attachments":[{"id":44378905,"asset_id":14264160,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33230232,"first_name":"James","last_name":"FitzGerald","domain_name":"independent","page_name":"JamesFitzGerald12","display_name":"James FitzGerald","profile_url":"https://independent.academia.edu/JamesFitzGerald12?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":48496,"name":"Delirium","url":"https://www.academia.edu/Documents/in/Delirium?f_ri=620049","nofollow":true},{"id":51570,"name":"Melatonin","url":"https://www.academia.edu/Documents/in/Melatonin?f_ri=620049","nofollow":true},{"id":106431,"name":"Sleep disorders","url":"https://www.academia.edu/Documents/in/Sleep_disorders?f_ri=620049","nofollow":true},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049","nofollow":true},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":643228,"name":"Ataxia","url":"https://www.academia.edu/Documents/in/Ataxia?f_ri=620049"},{"id":1627527,"name":"Cognition disorders","url":"https://www.academia.edu/Documents/in/Cognition_disorders?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_23776695" data-work_id="23776695" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/23776695/Microstructural_and_Functional_Connectivity_in_the_Developing_Preterm_Brain">Microstructural and Functional Connectivity in the Developing Preterm Brain</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Prematurely born children are at increased risk for cognitive deficits, but the neurobiological basis of these findings remains poorly understood. Since variations in neural circuitry may influence performance on cognitive tasks, recent... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_23776695" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Prematurely born children are at increased risk for cognitive deficits, but the neurobiological basis of these findings remains poorly understood. Since variations in neural circuitry may influence performance on cognitive tasks, recent investigations have explored the impact of preterm birth on connectivity in the developing brain. Diffusion tensor imaging studies demonstrate widespread alterations in fractional anisotropy, a measure of axonal integrity and microstructural connectivity, throughout the developing preterm brain. Functional connectivity studies report that preterm neonates, children and adolescents exhibit alterations in both resting state and task-based connectivity when compared to term control subjects. Taken together, these data suggest that neurodevelopmental impairment following preterm birth may represent a disease of neural connectivity.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/23776695" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="e6f21d7b9fce03f9d098c2ed2a8aff4a" rel="nofollow" data-download="{"attachment_id":44214518,"asset_id":23776695,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44214518/download_file?st=MTczOTk5NjI5Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="5659270" href="https://yale.academia.edu/ToddConstable">Todd Constable</a><script data-card-contents-for-user="5659270" type="text/json">{"id":5659270,"first_name":"Todd","last_name":"Constable","domain_name":"yale","page_name":"ToddConstable","display_name":"Todd Constable","profile_url":"https://yale.academia.edu/ToddConstable?f_ri=620049","photo":"https://0.academia-photos.com/5659270/2460785/2860022/s65_todd.constable.png"}</script></span></span></li><li class="js-paper-rank-work_23776695 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="23776695"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 23776695, container: ".js-paper-rank-work_23776695", }); 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Since variations in neural circuitry may influence performance on cognitive tasks, recent investigations have explored the impact of preterm birth on connectivity in the developing brain. Diffusion tensor imaging studies demonstrate widespread alterations in fractional anisotropy, a measure of axonal integrity and microstructural connectivity, throughout the developing preterm brain. Functional connectivity studies report that preterm neonates, children and adolescents exhibit alterations in both resting state and task-based connectivity when compared to term control subjects. Taken together, these data suggest that neurodevelopmental impairment following preterm birth may represent a disease of neural connectivity.","downloadable_attachments":[{"id":44214518,"asset_id":23776695,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":5659270,"first_name":"Todd","last_name":"Constable","domain_name":"yale","page_name":"ToddConstable","display_name":"Todd Constable","profile_url":"https://yale.academia.edu/ToddConstable?f_ri=620049","photo":"https://0.academia-photos.com/5659270/2460785/2860022/s65_todd.constable.png"}],"research_interests":[{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=620049","nofollow":true},{"id":52763,"name":"Functional 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Stress","url":"https://www.academia.edu/Documents/in/Oxidative_Stress?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="14406" rel="nofollow" href="https://www.academia.edu/Documents/in/Health">Health</a>, <script data-card-contents-for-ri="14406" type="text/json">{"id":14406,"name":"Health","url":"https://www.academia.edu/Documents/in/Health?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="23066" rel="nofollow" href="https://www.academia.edu/Documents/in/DNA_damage">DNA damage</a><script data-card-contents-for-ri="23066" type="text/json">{"id":23066,"name":"DNA damage","url":"https://www.academia.edu/Documents/in/DNA_damage?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=23886409]'), work: {"id":23886409,"title":"Increased consumption of wheat biofortified with selenium does not modify biomarkers of cancer risk, oxidative stress, or immune function in healthy Australian males","created_at":"2016-03-31T15:53:49.735-07:00","url":"https://www.academia.edu/23886409/Increased_consumption_of_wheat_biofortified_with_selenium_does_not_modify_biomarkers_of_cancer_risk_oxidative_stress_or_immune_function_in_healthy_Australian_males?f_ri=620049","dom_id":"work_23886409","summary":null,"downloadable_attachments":[{"id":44275640,"asset_id":23886409,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32879274,"first_name":"Michael","last_name":"Fenech","domain_name":"independent","page_name":"MichaelFenech","display_name":"Michael Fenech","profile_url":"https://independent.academia.edu/MichaelFenech?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":6697,"name":"Australia","url":"https://www.academia.edu/Documents/in/Australia?f_ri=620049","nofollow":true},{"id":14292,"name":"Oxidative Stress","url":"https://www.academia.edu/Documents/in/Oxidative_Stress?f_ri=620049","nofollow":true},{"id":14406,"name":"Health","url":"https://www.academia.edu/Documents/in/Health?f_ri=620049","nofollow":true},{"id":23066,"name":"DNA damage","url":"https://www.academia.edu/Documents/in/DNA_damage?f_ri=620049","nofollow":true},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=620049"},{"id":52055,"name":"Lipids","url":"https://www.academia.edu/Documents/in/Lipids?f_ri=620049"},{"id":58054,"name":"Environmental Sciences","url":"https://www.academia.edu/Documents/in/Environmental_Sciences?f_ri=620049"},{"id":95519,"name":"Selenium","url":"https://www.academia.edu/Documents/in/Selenium?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":202574,"name":"Feeding Behavior","url":"https://www.academia.edu/Documents/in/Feeding_Behavior?f_ri=620049"},{"id":279382,"name":"Comet Assay","url":"https://www.academia.edu/Documents/in/Comet_Assay?f_ri=620049"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=620049"},{"id":295452,"name":"C reactive protein","url":"https://www.academia.edu/Documents/in/C_reactive_protein?f_ri=620049"},{"id":324154,"name":"Immune system","url":"https://www.academia.edu/Documents/in/Immune_system?f_ri=620049"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=620049"},{"id":469018,"name":"Neoplasms","url":"https://www.academia.edu/Documents/in/Neoplasms?f_ri=620049"},{"id":568482,"name":"Biological markers","url":"https://www.academia.edu/Documents/in/Biological_markers?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":675427,"name":"Immune function","url":"https://www.academia.edu/Documents/in/Immune_function?f_ri=620049"},{"id":868560,"name":"Lymphocytes","url":"https://www.academia.edu/Documents/in/Lymphocytes?f_ri=620049"},{"id":991443,"name":"Triticum","url":"https://www.academia.edu/Documents/in/Triticum?f_ri=620049"},{"id":1133132,"name":"Environmental","url":"https://www.academia.edu/Documents/in/Environmental?f_ri=620049"},{"id":1212936,"name":"Cancer Risk","url":"https://www.academia.edu/Documents/in/Cancer_Risk?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_50593090" data-work_id="50593090" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/50593090/Risk_factors_among_handgun_retailers_for_frequent_and_disproportionate_sales_of_guns_used_in_violent_and_firearm_related_crimes">Risk factors among handgun retailers for frequent and disproportionate sales of guns used in violent and firearm related crimes</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">To determine the retailer and community level factors associated with frequent and disproportionate sales of handguns that are later used in violent and firearm related crimes (VFC handguns). Design: Cross sectional. The authors used... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_50593090" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">To determine the retailer and community level factors associated with frequent and disproportionate sales of handguns that are later used in violent and firearm related crimes (VFC handguns). Design: Cross sectional. The authors used California records to identify all handguns sold by study subjects during 1996-2000 and federal gun tracing records to determine which of these guns had been recovered by a police agency in the US or elsewhere and traced by 30 September 2003. Subjects and setting: The 421 licensed gun retailers in California selling at least 100 handguns annually during 1996-2000. Main outcome measure: The number of VFC handguns per 1000 gun years of exposure. Differences are expressed as incidence rate ratios (RR) with 95% confidence intervals (CI). Results: Subjects accounted for 11.7% of California retailers with handgun sales, 81.5% of handgun sales, and 85.5% of VFC handguns. Among subjects, the 3426 VFC handguns accounted for 48.0% of all traced handguns and 65.0% of those linked to a specified crime. The median VFC handgun trace rate was 0.5/ 1000 gun years (range 0-8.8). In multivariate analysis, this rate increased substantially for each singlepoint increase in the percentage of proposed sales that were denied because the purchasers were prohibited from owning guns (RR 1.43; 95% CI 1.32 to 1.56), and was increased for pawnbrokers (RR 1.26; 95% CI 1.02 to 1.55). Community level crime rates and sociodemographics had little predictive value. Conclusions: Risk factors, largely determined at the retailer level, exist for frequent and disproportionate sales of handguns that are later used in violent and firearm related crimes. Screening to identify high risk retailers could be undertaken with data that are already available.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/50593090" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="92322e111f308a01773a66b6ae5c9422" rel="nofollow" data-download="{"attachment_id":68516458,"asset_id":50593090,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/68516458/download_file?st=MTczOTk5NjI5Miw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32915435" href="https://duke.academia.edu/PhilipCook">Philip Cook</a><script data-card-contents-for-user="32915435" type="text/json">{"id":32915435,"first_name":"Philip","last_name":"Cook","domain_name":"duke","page_name":"PhilipCook","display_name":"Philip Cook","profile_url":"https://duke.academia.edu/PhilipCook?f_ri=620049","photo":"https://0.academia-photos.com/32915435/53301558/41426692/s65_philip.cook.jpg"}</script></span></span></li><li class="js-paper-rank-work_50593090 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="50593090"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 50593090, container: ".js-paper-rank-work_50593090", }); 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$(".js-view-count[data-work-id=50593090]").text(description); $(".js-view-count-work_50593090").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_50593090").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="50593090"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">13</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="1697" rel="nofollow" href="https://www.academia.edu/Documents/in/Violence">Violence</a>, <script data-card-contents-for-ri="1697" type="text/json">{"id":1697,"name":"Violence","url":"https://www.academia.edu/Documents/in/Violence?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="12159" rel="nofollow" href="https://www.academia.edu/Documents/in/Injury_Prevention">Injury Prevention</a>, <script data-card-contents-for-ri="12159" type="text/json">{"id":12159,"name":"Injury Prevention","url":"https://www.academia.edu/Documents/in/Injury_Prevention?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="41482" rel="nofollow" href="https://www.academia.edu/Documents/in/Multivariate_Analysis">Multivariate Analysis</a><script data-card-contents-for-ri="41482" type="text/json">{"id":41482,"name":"Multivariate Analysis","url":"https://www.academia.edu/Documents/in/Multivariate_Analysis?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=50593090]'), work: {"id":50593090,"title":"Risk factors among handgun retailers for frequent and disproportionate sales of guns used in violent and firearm related crimes","created_at":"2021-08-02T12:50:01.448-07:00","url":"https://www.academia.edu/50593090/Risk_factors_among_handgun_retailers_for_frequent_and_disproportionate_sales_of_guns_used_in_violent_and_firearm_related_crimes?f_ri=620049","dom_id":"work_50593090","summary":"To determine the retailer and community level factors associated with frequent and disproportionate sales of handguns that are later used in violent and firearm related crimes (VFC handguns). Design: Cross sectional. The authors used California records to identify all handguns sold by study subjects during 1996-2000 and federal gun tracing records to determine which of these guns had been recovered by a police agency in the US or elsewhere and traced by 30 September 2003. Subjects and setting: The 421 licensed gun retailers in California selling at least 100 handguns annually during 1996-2000. Main outcome measure: The number of VFC handguns per 1000 gun years of exposure. Differences are expressed as incidence rate ratios (RR) with 95% confidence intervals (CI). Results: Subjects accounted for 11.7% of California retailers with handgun sales, 81.5% of handgun sales, and 85.5% of VFC handguns. Among subjects, the 3426 VFC handguns accounted for 48.0% of all traced handguns and 65.0% of those linked to a specified crime. The median VFC handgun trace rate was 0.5/ 1000 gun years (range 0-8.8). In multivariate analysis, this rate increased substantially for each singlepoint increase in the percentage of proposed sales that were denied because the purchasers were prohibited from owning guns (RR 1.43; 95% CI 1.32 to 1.56), and was increased for pawnbrokers (RR 1.26; 95% CI 1.02 to 1.55). Community level crime rates and sociodemographics had little predictive value. Conclusions: Risk factors, largely determined at the retailer level, exist for frequent and disproportionate sales of handguns that are later used in violent and firearm related crimes. Screening to identify high risk retailers could be undertaken with data that are already available.","downloadable_attachments":[{"id":68516458,"asset_id":50593090,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32915435,"first_name":"Philip","last_name":"Cook","domain_name":"duke","page_name":"PhilipCook","display_name":"Philip Cook","profile_url":"https://duke.academia.edu/PhilipCook?f_ri=620049","photo":"https://0.academia-photos.com/32915435/53301558/41426692/s65_philip.cook.jpg"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=620049","nofollow":true},{"id":1697,"name":"Violence","url":"https://www.academia.edu/Documents/in/Violence?f_ri=620049","nofollow":true},{"id":12159,"name":"Injury Prevention","url":"https://www.academia.edu/Documents/in/Injury_Prevention?f_ri=620049","nofollow":true},{"id":41482,"name":"Multivariate Analysis","url":"https://www.academia.edu/Documents/in/Multivariate_Analysis?f_ri=620049","nofollow":true},{"id":50113,"name":"California","url":"https://www.academia.edu/Documents/in/California?f_ri=620049"},{"id":52982,"name":"Commerce","url":"https://www.academia.edu/Documents/in/Commerce?f_ri=620049"},{"id":67360,"name":"Crime","url":"https://www.academia.edu/Documents/in/Crime?f_ri=620049"},{"id":171648,"name":"Firearms","url":"https://www.academia.edu/Documents/in/Firearms?f_ri=620049"},{"id":174502,"name":"Incidence","url":"https://www.academia.edu/Documents/in/Incidence?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":1034181,"name":"Cross Sectional Studies","url":"https://www.academia.edu/Documents/in/Cross_Sectional_Studies?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_64358525" data-work_id="64358525" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/64358525/Management_of_the_Most_Severely_Injured_Spleen">Management of the Most Severely Injured Spleen</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Main Outcome Measures: Failure of NOM (f-NOM). Results: A total of 164 patients (42%) were operated on immediately. Of the remaining 224 who were offered a trial of NOM, the treatment failed in 85 patients (38%). At the end, 64% of... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_64358525" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Main Outcome Measures: Failure of NOM (f-NOM). Results: A total of 164 patients (42%) were operated on immediately. Of the remaining 224 who were offered a trial of NOM, the treatment failed in 85 patients (38%). At the end, 64% of patients required surgery. Multivariate analysis identified 2 independent predictors of f-NOM: grade V BSI and the presence of a brain injury. The likelihood of f-NOM was 32% if no predictor was present, 56% if 1 was present, and 100% if both were present. The mortality of patients for whom NOM failed was almost 7-fold higher than those with successful NOM (4.7% vs 0.7%; P =.07). Conclusions: Nearly two-thirds of patients with grade IV or V BSI require surgery. A grade V BSI and brain injury predict failure of NOM. This data must be taken into account when generalizations are made about the overall high success rates of NOM, which do not represent severe BSI.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/64358525" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="5e41145c41b976eb6e3ba66c70d0cbea" rel="nofollow" data-download="{"attachment_id":76430821,"asset_id":64358525,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/76430821/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="116043608" href="https://weillcornell.academia.edu/RobertWinchell">Robert Winchell</a><script data-card-contents-for-user="116043608" type="text/json">{"id":116043608,"first_name":"Robert","last_name":"Winchell","domain_name":"weillcornell","page_name":"RobertWinchell","display_name":"Robert Winchell","profile_url":"https://weillcornell.academia.edu/RobertWinchell?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_64358525 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="64358525"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 64358525, container: ".js-paper-rank-work_64358525", }); });</script></li><li class="js-percentile-work_64358525 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 64358525; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_64358525"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_64358525 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="64358525"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 64358525; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=64358525]").text(description); $(".js-view-count-work_64358525").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_64358525").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="64358525"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">13</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="49018" rel="nofollow" href="https://www.academia.edu/Documents/in/Spleen">Spleen</a>, <script data-card-contents-for-ri="49018" type="text/json">{"id":49018,"name":"Spleen","url":"https://www.academia.edu/Documents/in/Spleen?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="133057" rel="nofollow" href="https://www.academia.edu/Documents/in/Young_Adult">Young Adult</a>, <script data-card-contents-for-ri="133057" type="text/json">{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="192721" rel="nofollow" href="https://www.academia.edu/Documents/in/Risk_factors">Risk factors</a><script data-card-contents-for-ri="192721" type="text/json">{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=64358525]'), work: {"id":64358525,"title":"Management of the Most Severely Injured Spleen","created_at":"2021-12-15T12:22:41.551-08:00","url":"https://www.academia.edu/64358525/Management_of_the_Most_Severely_Injured_Spleen?f_ri=620049","dom_id":"work_64358525","summary":"Main Outcome Measures: Failure of NOM (f-NOM). Results: A total of 164 patients (42%) were operated on immediately. Of the remaining 224 who were offered a trial of NOM, the treatment failed in 85 patients (38%). At the end, 64% of patients required surgery. Multivariate analysis identified 2 independent predictors of f-NOM: grade V BSI and the presence of a brain injury. The likelihood of f-NOM was 32% if no predictor was present, 56% if 1 was present, and 100% if both were present. The mortality of patients for whom NOM failed was almost 7-fold higher than those with successful NOM (4.7% vs 0.7%; P =.07). Conclusions: Nearly two-thirds of patients with grade IV or V BSI require surgery. A grade V BSI and brain injury predict failure of NOM. This data must be taken into account when generalizations are made about the overall high success rates of NOM, which do not represent severe BSI.","downloadable_attachments":[{"id":76430821,"asset_id":64358525,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":116043608,"first_name":"Robert","last_name":"Winchell","domain_name":"weillcornell","page_name":"RobertWinchell","display_name":"Robert Winchell","profile_url":"https://weillcornell.academia.edu/RobertWinchell?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=620049","nofollow":true},{"id":49018,"name":"Spleen","url":"https://www.academia.edu/Documents/in/Spleen?f_ri=620049","nofollow":true},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=620049","nofollow":true},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=620049"},{"id":389732,"name":"New England","url":"https://www.academia.edu/Documents/in/New_England?f_ri=620049"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=620049"},{"id":2190600,"name":"Splenectomy","url":"https://www.academia.edu/Documents/in/Splenectomy?f_ri=620049"},{"id":2463666,"name":"Trauma Centers","url":"https://www.academia.edu/Documents/in/Trauma_Centers?f_ri=620049"},{"id":2467531,"name":"Trauma Severity Indices","url":"https://www.academia.edu/Documents/in/Trauma_Severity_Indices?f_ri=620049"},{"id":3306139,"name":"Treatment Failure","url":"https://www.academia.edu/Documents/in/Treatment_Failure?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_14213397 coauthored" data-work_id="14213397" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/14213397/Factors_associated_with_failure_to_rescue_in_patients_undergoing_trauma_laparotomy">Factors associated with failure-to-rescue in patients undergoing trauma laparotomy</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Introduction. Quality improvement initiatives have focused primarily on preventing in-hospital complications. Patients developing complications are at a greater risk of mortality; however, factors associated with failure-to-rescue (death... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_14213397" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Introduction. Quality improvement initiatives have focused primarily on preventing in-hospital complications. Patients developing complications are at a greater risk of mortality; however, factors associated with failure-to-rescue (death after major complication) in trauma patients remain undefined. The aim of this study was to identify risk factors associated with failure-to-rescue in patients undergoing trauma laparotomy.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/14213397" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="06eff83456be24110408c9ec7a48d0b4" rel="nofollow" data-download="{"attachment_id":44459121,"asset_id":14213397,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44459121/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33199202" href="https://independent.academia.edu/TerenceOKeeffe">Terence O'Keeffe</a><script data-card-contents-for-user="33199202" type="text/json">{"id":33199202,"first_name":"Terence","last_name":"O'Keeffe","domain_name":"independent","page_name":"TerenceOKeeffe","display_name":"Terence O'Keeffe","profile_url":"https://independent.academia.edu/TerenceOKeeffe?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-14213397">+1</span><div class="hidden js-additional-users-14213397"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/PeterRhee">Peter Rhee</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-14213397'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-14213397').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_14213397 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="14213397"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 14213397, container: ".js-paper-rank-work_14213397", }); });</script></li><li class="js-percentile-work_14213397 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14213397; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_14213397"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_14213397 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="14213397"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14213397; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14213397]").text(description); $(".js-view-count-work_14213397").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_14213397").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="14213397"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">11</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="647" rel="nofollow" href="https://www.academia.edu/Documents/in/Surgery">Surgery</a>, <script data-card-contents-for-ri="647" type="text/json">{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="49633" rel="nofollow" href="https://www.academia.edu/Documents/in/Heart_Failure">Heart Failure</a>, <script data-card-contents-for-ri="49633" type="text/json">{"id":49633,"name":"Heart Failure","url":"https://www.academia.edu/Documents/in/Heart_Failure?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="99698" rel="nofollow" href="https://www.academia.edu/Documents/in/Resuscitation">Resuscitation</a>, <script data-card-contents-for-ri="99698" type="text/json">{"id":99698,"name":"Resuscitation","url":"https://www.academia.edu/Documents/in/Resuscitation?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="109739" rel="nofollow" href="https://www.academia.edu/Documents/in/Infection">Infection</a><script data-card-contents-for-ri="109739" type="text/json">{"id":109739,"name":"Infection","url":"https://www.academia.edu/Documents/in/Infection?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=14213397]'), work: {"id":14213397,"title":"Factors associated with failure-to-rescue in patients undergoing trauma laparotomy","created_at":"2015-07-20T09:39:34.203-07:00","url":"https://www.academia.edu/14213397/Factors_associated_with_failure_to_rescue_in_patients_undergoing_trauma_laparotomy?f_ri=620049","dom_id":"work_14213397","summary":"Introduction. Quality improvement initiatives have focused primarily on preventing in-hospital complications. Patients developing complications are at a greater risk of mortality; however, factors associated with failure-to-rescue (death after major complication) in trauma patients remain undefined. The aim of this study was to identify risk factors associated with failure-to-rescue in patients undergoing trauma laparotomy.","downloadable_attachments":[{"id":44459121,"asset_id":14213397,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33199202,"first_name":"Terence","last_name":"O'Keeffe","domain_name":"independent","page_name":"TerenceOKeeffe","display_name":"Terence O'Keeffe","profile_url":"https://independent.academia.edu/TerenceOKeeffe?f_ri=620049","photo":"/images/s65_no_pic.png"},{"id":38264902,"first_name":"Peter","last_name":"Rhee","domain_name":"independent","page_name":"PeterRhee","display_name":"Peter Rhee","profile_url":"https://independent.academia.edu/PeterRhee?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery?f_ri=620049","nofollow":true},{"id":49633,"name":"Heart Failure","url":"https://www.academia.edu/Documents/in/Heart_Failure?f_ri=620049","nofollow":true},{"id":99698,"name":"Resuscitation","url":"https://www.academia.edu/Documents/in/Resuscitation?f_ri=620049","nofollow":true},{"id":109739,"name":"Infection","url":"https://www.academia.edu/Documents/in/Infection?f_ri=620049","nofollow":true},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=620049"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=620049"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":1294607,"name":"Logistic Models","url":"https://www.academia.edu/Documents/in/Logistic_Models?f_ri=620049"},{"id":2416686,"name":"Laparotomy","url":"https://www.academia.edu/Documents/in/Laparotomy?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_13844062" data-work_id="13844062" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13844062/Epidemiology_of_the_epilepsies">Epidemiology of the epilepsies</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13844062" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a4f072b81e4d1332936a36c7a04d0c08" rel="nofollow" data-download="{"attachment_id":44888327,"asset_id":13844062,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44888327/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32936371" href="https://ucl.academia.edu/JosemirSander">Ley Sander</a><script data-card-contents-for-user="32936371" type="text/json">{"id":32936371,"first_name":"Ley","last_name":"Sander","domain_name":"ucl","page_name":"JosemirSander","display_name":"Ley Sander","profile_url":"https://ucl.academia.edu/JosemirSander?f_ri=620049","photo":"https://0.academia-photos.com/32936371/13032276/14375798/s65_ley.sander.png"}</script></span></span></li><li class="js-paper-rank-work_13844062 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="13844062"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 13844062, container: ".js-paper-rank-work_13844062", }); });</script></li><li 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itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/18159969/Pathological_Conditions_of_the_Reproductive_Organs_of_Male_Stray_Dogs_in_the_Tropics_Prevalence_Risk_Factors_Morphological_Findings_and_Testosterone_Concentrations">Pathological Conditions of the Reproductive Organs of Male Stray Dogs in the Tropics: Prevalence, Risk Factors, Morphological Findings and Testosterone Concentrations</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The objective of this study was to estimate the prevalence of and risk factors for pathological conditions of the reproductive organs in stray dogs under tropical conditions. Three hundred and eighteen dogs were examined post-mortem in... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_18159969" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The objective of this study was to estimate the prevalence of and risk factors for pathological conditions of the reproductive organs in stray dogs under tropical conditions. Three hundred and eighteen dogs were examined post-mortem in the period from 1 July 2002 to 30 June 2003. Before killing, a blood sample (from the cephalic vein) for testosterone assay was taken. Pathological conditions of the reproductive organs were found in 135 of the dogs (42.5%) and in 175 of the testes (64.8%). The most frequent pathologies found were testicular degeneration, cryptorchidism, testicular hypoplasia and testicular tumours (in 15.1%, 6.6%, 6.6% and 5.4% of the dogs and 15.1, 4.6, 6.0 and 3.5 of the testes, respectively). Transmissible venereal tumour (TVT) was seen in 5.4% of the dogs. Testicular degeneration was more common in old dogs and underweight dogs (p &amp;lt; 0.05). Testicular tumours were 14.3 times more common in cryptorchid dogs. Age was another important factor for the development of testicular tumours (p &amp;lt; 0.05). Lower levels of testosterone concentration (p &amp;lt; 0.05) were observed in dogs with advanced testicular degeneration (0.7 +/- 0.8 nM), dogs with hypoplastic testicles (0.8 +/- 0.9 nM) and dogs with one degenerated and one retained testis or with bilateral cryptorchidism (1.2 +/- 0.9 nM) compared to dogs with one or two normal testes (7.0 +/- 5.5 nM). Testicular volume and weight were significantly lower in degenerated, hypoplastic and retained testes compared with the contralateral normal testis. Some spermatogenic activity was found in three of the retained testes, producing oligozoospermic smears with a high percentage of sperm abnormalities. No comparable epidemiological data about male pathological conditions of the reproductive organs in the dog is available. 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Three hundred and eighteen dogs were examined post-mortem in the period from 1 July 2002 to 30 June 2003. Before killing, a blood sample (from the cephalic vein) for testosterone assay was taken. Pathological conditions of the reproductive organs were found in 135 of the dogs (42.5%) and in 175 of the testes (64.8%). The most frequent pathologies found were testicular degeneration, cryptorchidism, testicular hypoplasia and testicular tumours (in 15.1%, 6.6%, 6.6% and 5.4% of the dogs and 15.1, 4.6, 6.0 and 3.5 of the testes, respectively). Transmissible venereal tumour (TVT) was seen in 5.4% of the dogs. Testicular degeneration was more common in old dogs and underweight dogs (p \u0026amp;lt; 0.05). Testicular tumours were 14.3 times more common in cryptorchid dogs. Age was another important factor for the development of testicular tumours (p \u0026amp;lt; 0.05). Lower levels of testosterone concentration (p \u0026amp;lt; 0.05) were observed in dogs with advanced testicular degeneration (0.7 +/- 0.8 nM), dogs with hypoplastic testicles (0.8 +/- 0.9 nM) and dogs with one degenerated and one retained testis or with bilateral cryptorchidism (1.2 +/- 0.9 nM) compared to dogs with one or two normal testes (7.0 +/- 5.5 nM). Testicular volume and weight were significantly lower in degenerated, hypoplastic and retained testes compared with the contralateral normal testis. Some spermatogenic activity was found in three of the retained testes, producing oligozoospermic smears with a high percentage of sperm abnormalities. No comparable epidemiological data about male pathological conditions of the reproductive organs in the dog is available. The prevalence found in this study, yet, appears high.","downloadable_attachments":[{"id":42189009,"asset_id":18159969,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":38126392,"first_name":"Antonio","last_name":"Ortega-pacheco","domain_name":"independent","page_name":"AntonioOrtegapacheco","display_name":"Antonio Ortega-pacheco","profile_url":"https://independent.academia.edu/AntonioOrtegapacheco?f_ri=620049","photo":"/images/s65_no_pic.png"},{"id":38212196,"first_name":"Catharina","last_name":"Linde Forsberg","domain_name":"independent","page_name":"CatharinaForsberg","display_name":"Catharina Linde Forsberg","profile_url":"https://independent.academia.edu/CatharinaForsberg?f_ri=620049","photo":"https://0.academia-photos.com/38212196/10664126/11905089/s65_catharina.forsberg.jpg"},{"id":38213120,"first_name":"Matilde","last_name":"Jimenez-coello","domain_name":"diaarroba","page_name":"MatildeJimenezcoello","display_name":"Matilde Jimenez-coello","profile_url":"https://diaarroba.academia.edu/MatildeJimenezcoello?f_ri=620049","photo":"https://0.academia-photos.com/38213120/10664258/11905235/s65_matilde.jimenez-coello.jpg"}],"research_interests":[{"id":4559,"name":"Reproduction","url":"https://www.academia.edu/Documents/in/Reproduction?f_ri=620049","nofollow":true},{"id":43881,"name":"Mexico","url":"https://www.academia.edu/Documents/in/Mexico?f_ri=620049","nofollow":true},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=620049","nofollow":true},{"id":52438,"name":"Dogs","url":"https://www.academia.edu/Documents/in/Dogs?f_ri=620049","nofollow":true},{"id":69056,"name":"Testosterone","url":"https://www.academia.edu/Documents/in/Testosterone?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":208580,"name":"Cryptorchidism","url":"https://www.academia.edu/Documents/in/Cryptorchidism?f_ri=620049"},{"id":289330,"name":"Prevalence","url":"https://www.academia.edu/Documents/in/Prevalence?f_ri=620049"},{"id":546419,"name":"Age Factors","url":"https://www.academia.edu/Documents/in/Age_Factors?f_ri=620049"},{"id":617771,"name":"MEXICO","url":"https://www.academia.edu/Documents/in/MEXICO-2015?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":862371,"name":"Spermatozoa","url":"https://www.academia.edu/Documents/in/Spermatozoa?f_ri=620049"},{"id":906876,"name":"Tropical Climate","url":"https://www.academia.edu/Documents/in/Tropical_Climate?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_82043723" data-work_id="82043723" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/82043723/Prevalence_and_correlates_of_being_bullied_among_in_school_adolescents_in_Beijing_results_from_the_2003_Beijing_Global_School_Based_Health_Survey">Prevalence and correlates of being bullied among in-school adolescents in Beijing: results from the 2003 Beijing Global School-Based Health Survey</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Background Bullying has public health importance. It has been reported that both the victims and perpetrators of bullying are more likely to have suicidal ideation and other suicidal behaviours. Moreover, bullying can be a precursor for... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_82043723" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Background Bullying has public health importance. It has been reported that both the victims and perpetrators of bullying are more likely to have suicidal ideation and other suicidal behaviours. Moreover, bullying can be a precursor for school violence and can contribute to poor academic performance. The purpose of the study was to raise awareness on the subject in China. We, therefore conducted an analysis of secondary data to determine the prevalence and correlates of having been bullied among in-school adolescents. Methods The data was taken from the Beijing Global School-Based Health Survey conducted in 2003. A weighted analysis to reduce bias due to differing patterns of non-response was conducted using statistical software (SPSS version 14.0). We conducted a backward logistic regression analysis to determine independent predictors for being bullied. Results Out of a total of 2,348 in-school adolescents who participated in the survey, 20% (23% males, and 17% females) reported h...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/82043723" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="69ac25e34054ea5b34ac201484929028" rel="nofollow" data-download="{"attachment_id":87876148,"asset_id":82043723,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/87876148/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="28151851" href="https://medcol.academia.edu/AdamsonMuula">Adamson Muula</a><script data-card-contents-for-user="28151851" type="text/json">{"id":28151851,"first_name":"Adamson","last_name":"Muula","domain_name":"medcol","page_name":"AdamsonMuula","display_name":"Adamson Muula","profile_url":"https://medcol.academia.edu/AdamsonMuula?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_82043723 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="82043723"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 82043723, container: ".js-paper-rank-work_82043723", }); 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$(".js-view-count[data-work-id=82043723]").text(description); $(".js-view-count-work_82043723").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_82043723").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="82043723"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">13</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="16288" rel="nofollow" href="https://www.academia.edu/Documents/in/Public_Health">Public Health</a>, <script data-card-contents-for-ri="16288" type="text/json">{"id":16288,"name":"Public Health","url":"https://www.academia.edu/Documents/in/Public_Health?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="76424" rel="nofollow" href="https://www.academia.edu/Documents/in/Academic_Performance">Academic Performance</a><script data-card-contents-for-ri="76424" type="text/json">{"id":76424,"name":"Academic Performance","url":"https://www.academia.edu/Documents/in/Academic_Performance?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=82043723]'), work: {"id":82043723,"title":"Prevalence and correlates of being bullied among in-school adolescents in Beijing: results from the 2003 Beijing Global School-Based Health Survey","created_at":"2022-06-22T02:55:05.624-07:00","url":"https://www.academia.edu/82043723/Prevalence_and_correlates_of_being_bullied_among_in_school_adolescents_in_Beijing_results_from_the_2003_Beijing_Global_School_Based_Health_Survey?f_ri=620049","dom_id":"work_82043723","summary":"Background Bullying has public health importance. It has been reported that both the victims and perpetrators of bullying are more likely to have suicidal ideation and other suicidal behaviours. Moreover, bullying can be a precursor for school violence and can contribute to poor academic performance. The purpose of the study was to raise awareness on the subject in China. We, therefore conducted an analysis of secondary data to determine the prevalence and correlates of having been bullied among in-school adolescents. Methods The data was taken from the Beijing Global School-Based Health Survey conducted in 2003. A weighted analysis to reduce bias due to differing patterns of non-response was conducted using statistical software (SPSS version 14.0). We conducted a backward logistic regression analysis to determine independent predictors for being bullied. Results Out of a total of 2,348 in-school adolescents who participated in the survey, 20% (23% males, and 17% females) reported h...","downloadable_attachments":[{"id":87876148,"asset_id":82043723,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":28151851,"first_name":"Adamson","last_name":"Muula","domain_name":"medcol","page_name":"AdamsonMuula","display_name":"Adamson Muula","profile_url":"https://medcol.academia.edu/AdamsonMuula?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=620049","nofollow":true},{"id":16288,"name":"Public Health","url":"https://www.academia.edu/Documents/in/Public_Health?f_ri=620049","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=620049","nofollow":true},{"id":76424,"name":"Academic Performance","url":"https://www.academia.edu/Documents/in/Academic_Performance?f_ri=620049","nofollow":true},{"id":105245,"name":"School Health","url":"https://www.academia.edu/Documents/in/School_Health?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":198462,"name":"Statistical software","url":"https://www.academia.edu/Documents/in/Statistical_software?f_ri=620049"},{"id":212320,"name":"Logistic Regression Analysis","url":"https://www.academia.edu/Documents/in/Logistic_Regression_Analysis?f_ri=620049"},{"id":378819,"name":"Suicidal Ideation","url":"https://www.academia.edu/Documents/in/Suicidal_Ideation?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":1265252,"name":"Health Survey","url":"https://www.academia.edu/Documents/in/Health_Survey?f_ri=620049"},{"id":1587858,"name":"Confidence Interval","url":"https://www.academia.edu/Documents/in/Confidence_Interval?f_ri=620049"},{"id":2234207,"name":"Protective Factor","url":"https://www.academia.edu/Documents/in/Protective_Factor?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_12139682" data-work_id="12139682" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/12139682/Functional_outcome_at_school_age_of_preterm_born_children_treated_with_high_dose_dexamethasone">Functional outcome at school age of preterm-born children treated with high-dose dexamethasone</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Background: Postnatal dexamethasone (DXM) treatment is associated with adverse motor outcome. It is largely unknown as to what extent functional outcome at school age is affected. Aims: Our first aim was to determine motor, cognitive, and... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_12139682" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Background: Postnatal dexamethasone (DXM) treatment is associated with adverse motor outcome. It is largely unknown as to what extent functional outcome at school age is affected. Aims: Our first aim was to determine motor, cognitive, and behavioural outcome at school age of preterm-born children treated with high-dose DXM for pulmonary problems. Our second aim was to identify DXM-related risk factors for adverse outcome. Study design: In this cohort study, we included 53 very preterm-born children treated with DXM (starting dose 0.5 mg/kg/d) after the first week of life. At the median age of 9 years, we performed a detailed neuropsychological assessment. Results: Compared to the norm population, DXM-treated children scored worse on the Movement-ABC (abnormal fine motor, ball skills and balance: 59%, 47% and 30%, respectively). They more often had total (36%), verbal (32%) and performance IQs (55%) below 85 (P b .001, P = .002, P b .001, respectively). On each of the remaining measures, DXM-treated children scored worse than the norm population, except for verbal long-term memory and verbal recognition memory. DXM-related risk factors were associated with poorer performance. Conclusions: At school age, multiple domains of functional outcome were affected in DXM-treated children. Risk factors related to the use of DXM should be considered as serious potentiaters of adverse outcome in children treated with high-dose DXM. Please cite this article as: Hitzert MM, et al, Functional outcome at school age of preterm-born children treated with high-dose dexamethasone, Early Hum Dev (2014), http://dx.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/12139682" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="cf17d4998c1511d232ca714fc9f1d4db" rel="nofollow" data-download="{"attachment_id":46336059,"asset_id":12139682,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46336059/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="30447317" href="https://independent.academia.edu/MarritHitzert">Marrit Hitzert</a><script data-card-contents-for-user="30447317" type="text/json">{"id":30447317,"first_name":"Marrit","last_name":"Hitzert","domain_name":"independent","page_name":"MarritHitzert","display_name":"Marrit Hitzert","profile_url":"https://independent.academia.edu/MarritHitzert?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_12139682 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="12139682"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 12139682, container: ".js-paper-rank-work_12139682", }); 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It is largely unknown as to what extent functional outcome at school age is affected. Aims: Our first aim was to determine motor, cognitive, and behavioural outcome at school age of preterm-born children treated with high-dose DXM for pulmonary problems. Our second aim was to identify DXM-related risk factors for adverse outcome. Study design: In this cohort study, we included 53 very preterm-born children treated with DXM (starting dose 0.5 mg/kg/d) after the first week of life. At the median age of 9 years, we performed a detailed neuropsychological assessment. Results: Compared to the norm population, DXM-treated children scored worse on the Movement-ABC (abnormal fine motor, ball skills and balance: 59%, 47% and 30%, respectively). They more often had total (36%), verbal (32%) and performance IQs (55%) below 85 (P b .001, P = .002, P b .001, respectively). On each of the remaining measures, DXM-treated children scored worse than the norm population, except for verbal long-term memory and verbal recognition memory. DXM-related risk factors were associated with poorer performance. Conclusions: At school age, multiple domains of functional outcome were affected in DXM-treated children. Risk factors related to the use of DXM should be considered as serious potentiaters of adverse outcome in children treated with high-dose DXM. Please cite this article as: Hitzert MM, et al, Functional outcome at school age of preterm-born children treated with high-dose dexamethasone, Early Hum Dev (2014), http://dx.","downloadable_attachments":[{"id":46336059,"asset_id":12139682,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":30447317,"first_name":"Marrit","last_name":"Hitzert","domain_name":"independent","page_name":"MarritHitzert","display_name":"Marrit Hitzert","profile_url":"https://independent.academia.edu/MarritHitzert?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=620049","nofollow":true},{"id":4212,"name":"Cognition","url":"https://www.academia.edu/Documents/in/Cognition?f_ri=620049","nofollow":true},{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=620049","nofollow":true},{"id":33732,"name":"Executive Function","url":"https://www.academia.edu/Documents/in/Executive_Function?f_ri=620049","nofollow":true},{"id":50709,"name":"Visual Long Term Memory","url":"https://www.academia.edu/Documents/in/Visual_Long_Term_Memory?f_ri=620049"},{"id":57801,"name":"Dexamethasone","url":"https://www.academia.edu/Documents/in/Dexamethasone?f_ri=620049"},{"id":57810,"name":"Child Behavior","url":"https://www.academia.edu/Documents/in/Child_Behavior?f_ri=620049"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":633452,"name":"Bronchopulmonary Dysplasia","url":"https://www.academia.edu/Documents/in/Bronchopulmonary_Dysplasia?f_ri=620049"},{"id":1293308,"name":"Glucocorticoids","url":"https://www.academia.edu/Documents/in/Glucocorticoids?f_ri=620049"},{"id":1399301,"name":"Premature Birth","url":"https://www.academia.edu/Documents/in/Premature_Birth?f_ri=620049"},{"id":1627527,"name":"Cognition disorders","url":"https://www.academia.edu/Documents/in/Cognition_disorders?f_ri=620049"},{"id":1756573,"name":"Motor Skills","url":"https://www.academia.edu/Documents/in/Motor_Skills?f_ri=620049"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=620049"},{"id":2467548,"name":"Neuropsychological Tests","url":"https://www.academia.edu/Documents/in/Neuropsychological_Tests?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_12591933 coauthored" data-work_id="12591933" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/12591933/Cash_Transfers_Behavioral_Changes_and_Cognitive_Development_in_Early_Childhood_Evidence_from_a_Randomized_Experiment">Cash Transfers, Behavioral Changes, and Cognitive Development in Early Childhood: Evidence from a Randomized Experiment</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">This paper analyzes the impact of a randomized cash transfer program on cognitive development in early childhood in rural Nicaragua. We first show that a very large sample of children in our sample are delayed along various dimensions,... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_12591933" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">This paper analyzes the impact of a randomized cash transfer program on cognitive development in early childhood in rural Nicaragua. We first show that a very large sample of children in our sample are delayed along various dimensions, including language, memory, and social skills, and that these delays are related to household per capita expenditure levels. We then show that the program had significant effects on cognitive outcomes, especially language. Program impacts are larger for older pre-school aged children, who were also more likely to be delayed. We analyze how the program affected several inputs into early childhood development that have been identified as key risk factors in the literature. Households randomly assigned to receive transfers increased the consumption of nutritious foods and provided more cognitive stimulation to children than those assigned to the control group. Moreover, we show that these impacts are not due to the cash component of the program only. The expenditure patterns of beneficiary households are significantly different from those of control households, indicating that households do not spend the cash received through the program in the same way as other income. Thomas, D. 1994. "Like Father, Like Son, Like Mother, Like Daughter: Parental Resources and Child</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/12591933" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="0ca5d76c352fe1874245af5402b2b4a2" rel="nofollow" data-download="{"attachment_id":46064901,"asset_id":12591933,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46064901/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="39230833" href="https://independent.academia.edu/RenosVakis">Renos Vakis</a><script data-card-contents-for-user="39230833" type="text/json">{"id":39230833,"first_name":"Renos","last_name":"Vakis","domain_name":"independent","page_name":"RenosVakis","display_name":"Renos Vakis","profile_url":"https://independent.academia.edu/RenosVakis?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-12591933">+1</span><div class="hidden js-additional-users-12591933"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://iadb.academia.edu/NorbertSchady">Norbert Schady</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-12591933'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-12591933').html(); 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container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_12591933 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="12591933"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 12591933; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=12591933]").text(description); $(".js-view-count-work_12591933").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_12591933").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="12591933"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">21</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="2971" rel="nofollow" href="https://www.academia.edu/Documents/in/Cognitive_development">Cognitive development</a>, <script data-card-contents-for-ri="2971" type="text/json">{"id":2971,"name":"Cognitive development","url":"https://www.academia.edu/Documents/in/Cognitive_development?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4441" rel="nofollow" href="https://www.academia.edu/Documents/in/Health_Care">Health Care</a>, <script data-card-contents-for-ri="4441" type="text/json">{"id":4441,"name":"Health Care","url":"https://www.academia.edu/Documents/in/Health_Care?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4583" rel="nofollow" href="https://www.academia.edu/Documents/in/Child_Development">Child Development</a>, <script data-card-contents-for-ri="4583" type="text/json">{"id":4583,"name":"Child Development","url":"https://www.academia.edu/Documents/in/Child_Development?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="5547" rel="nofollow" href="https://www.academia.edu/Documents/in/Policy">Policy</a><script data-card-contents-for-ri="5547" type="text/json">{"id":5547,"name":"Policy","url":"https://www.academia.edu/Documents/in/Policy?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=12591933]'), work: {"id":12591933,"title":"Cash Transfers, Behavioral Changes, and Cognitive Development in Early Childhood: Evidence from a Randomized Experiment","created_at":"2015-05-25T18:36:08.136-07:00","url":"https://www.academia.edu/12591933/Cash_Transfers_Behavioral_Changes_and_Cognitive_Development_in_Early_Childhood_Evidence_from_a_Randomized_Experiment?f_ri=620049","dom_id":"work_12591933","summary":"This paper analyzes the impact of a randomized cash transfer program on cognitive development in early childhood in rural Nicaragua. We first show that a very large sample of children in our sample are delayed along various dimensions, including language, memory, and social skills, and that these delays are related to household per capita expenditure levels. We then show that the program had significant effects on cognitive outcomes, especially language. Program impacts are larger for older pre-school aged children, who were also more likely to be delayed. We analyze how the program affected several inputs into early childhood development that have been identified as key risk factors in the literature. Households randomly assigned to receive transfers increased the consumption of nutritious foods and provided more cognitive stimulation to children than those assigned to the control group. Moreover, we show that these impacts are not due to the cash component of the program only. The expenditure patterns of beneficiary households are significantly different from those of control households, indicating that households do not spend the cash received through the program in the same way as other income. Thomas, D. 1994. \"Like Father, Like Son, Like Mother, Like Daughter: Parental Resources and Child","downloadable_attachments":[{"id":46064901,"asset_id":12591933,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":39230833,"first_name":"Renos","last_name":"Vakis","domain_name":"independent","page_name":"RenosVakis","display_name":"Renos Vakis","profile_url":"https://independent.academia.edu/RenosVakis?f_ri=620049","photo":"/images/s65_no_pic.png"},{"id":31529839,"first_name":"Norbert","last_name":"Schady","domain_name":"iadb","page_name":"NorbertSchady","display_name":"Norbert Schady","profile_url":"https://iadb.academia.edu/NorbertSchady?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":2971,"name":"Cognitive development","url":"https://www.academia.edu/Documents/in/Cognitive_development?f_ri=620049","nofollow":true},{"id":4441,"name":"Health Care","url":"https://www.academia.edu/Documents/in/Health_Care?f_ri=620049","nofollow":true},{"id":4583,"name":"Child Development","url":"https://www.academia.edu/Documents/in/Child_Development?f_ri=620049","nofollow":true},{"id":5547,"name":"Policy","url":"https://www.academia.edu/Documents/in/Policy?f_ri=620049","nofollow":true},{"id":14042,"name":"Human Capital","url":"https://www.academia.edu/Documents/in/Human_Capital?f_ri=620049"},{"id":27659,"name":"Applied Economics","url":"https://www.academia.edu/Documents/in/Applied_Economics?f_ri=620049"},{"id":30140,"name":"Early Childhood","url":"https://www.academia.edu/Documents/in/Early_Childhood?f_ri=620049"},{"id":64987,"name":"Social Development","url":"https://www.academia.edu/Documents/in/Social_Development?f_ri=620049"},{"id":70854,"name":"Developing Country","url":"https://www.academia.edu/Documents/in/Developing_Country?f_ri=620049"},{"id":88382,"name":"Primary Education","url":"https://www.academia.edu/Documents/in/Primary_Education?f_ri=620049"},{"id":105245,"name":"School Health","url":"https://www.academia.edu/Documents/in/School_Health?f_ri=620049"},{"id":132270,"name":"Developing World","url":"https://www.academia.edu/Documents/in/Developing_World?f_ri=620049"},{"id":134627,"name":"Behavior change","url":"https://www.academia.edu/Documents/in/Behavior_change?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":213658,"name":"Health monitoring","url":"https://www.academia.edu/Documents/in/Health_monitoring?f_ri=620049"},{"id":216818,"name":"Early Childhood Development","url":"https://www.academia.edu/Documents/in/Early_Childhood_Development?f_ri=620049"},{"id":291620,"name":"Social Skill","url":"https://www.academia.edu/Documents/in/Social_Skill?f_ri=620049"},{"id":403046,"name":"Cash Transfers","url":"https://www.academia.edu/Documents/in/Cash_Transfers?f_ri=620049"},{"id":538047,"name":"Young Children","url":"https://www.academia.edu/Documents/in/Young_Children?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":877360,"name":"Conditional cash transfer programs","url":"https://www.academia.edu/Documents/in/Conditional_cash_transfer_programs?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_72086800" data-work_id="72086800" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/72086800/Body_mass_index_and_waist_height_ratio_for_prediction_of_severity_of_coronary_artery_disease">Body mass index and waist/height ratio for prediction of severity of coronary artery disease</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Background To determine whether waist-to-height ratio correlates with coronary artery disease (CAD) severity better, than the body mass index (BMI) as assessed by coronary angiography in Bangladeshi population. Methods This cross... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_72086800" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Background To determine whether waist-to-height ratio correlates with coronary artery disease (CAD) severity better, than the body mass index (BMI) as assessed by coronary angiography in Bangladeshi population. Methods This cross sectional study was done on patients in Department of Cardiology in DMCH and those referred in the cath-lab of the Department of Cardiology for CAG during November 2009 to October 2010 involving 120 patients. They were divided into group-A (with coronary score ≥7) and group-B (coronary score &lt;7) depending on Gensisni score. Result There were no statistically significant difference regarding the distribution of age, sex and clinical diagnosis and parameters between the two groups. The mean age of patients was 51.7 ± 8.2 years and 48.8 ± 9.1 years in Group A and Group B respectively with a male predominance in both the groups. Patients in group A had higher BMI ≥25 and waist to height ratio (≥0.55) than Group B which showed a statistically significant asso...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/72086800" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="8569c011c11f5c41bfc6e0ef85e67cbc" rel="nofollow" data-download="{"attachment_id":81157848,"asset_id":72086800,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/81157848/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="27477844" href="https://independent.academia.edu/khandkerMdNurusSabah">khandker Md Nurus Sabah</a><script data-card-contents-for-user="27477844" type="text/json">{"id":27477844,"first_name":"khandker Md","last_name":"Nurus Sabah","domain_name":"independent","page_name":"khandkerMdNurusSabah","display_name":"khandker Md Nurus Sabah","profile_url":"https://independent.academia.edu/khandkerMdNurusSabah?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_72086800 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="72086800"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 72086800, container: ".js-paper-rank-work_72086800", }); });</script></li><li class="js-percentile-work_72086800 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 72086800; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_72086800"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_72086800 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="72086800"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 72086800; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=72086800]").text(description); $(".js-view-count-work_72086800").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_72086800").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="72086800"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">14</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="18895" rel="nofollow" href="https://www.academia.edu/Documents/in/Bangladesh">Bangladesh</a>, <script data-card-contents-for-ri="18895" type="text/json">{"id":18895,"name":"Bangladesh","url":"https://www.academia.edu/Documents/in/Bangladesh?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="41482" rel="nofollow" href="https://www.academia.edu/Documents/in/Multivariate_Analysis">Multivariate Analysis</a>, <script data-card-contents-for-ri="41482" type="text/json">{"id":41482,"name":"Multivariate Analysis","url":"https://www.academia.edu/Documents/in/Multivariate_Analysis?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="192564" rel="nofollow" href="https://www.academia.edu/Documents/in/Body_Mass_Index">Body Mass Index</a><script data-card-contents-for-ri="192564" type="text/json">{"id":192564,"name":"Body Mass Index","url":"https://www.academia.edu/Documents/in/Body_Mass_Index?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=72086800]'), work: {"id":72086800,"title":"Body mass index and waist/height ratio for prediction of severity of coronary artery disease","created_at":"2022-02-21T03:50:22.190-08:00","url":"https://www.academia.edu/72086800/Body_mass_index_and_waist_height_ratio_for_prediction_of_severity_of_coronary_artery_disease?f_ri=620049","dom_id":"work_72086800","summary":"Background To determine whether waist-to-height ratio correlates with coronary artery disease (CAD) severity better, than the body mass index (BMI) as assessed by coronary angiography in Bangladeshi population. Methods This cross sectional study was done on patients in Department of Cardiology in DMCH and those referred in the cath-lab of the Department of Cardiology for CAG during November 2009 to October 2010 involving 120 patients. They were divided into group-A (with coronary score ≥7) and group-B (coronary score \u0026lt;7) depending on Gensisni score. Result There were no statistically significant difference regarding the distribution of age, sex and clinical diagnosis and parameters between the two groups. The mean age of patients was 51.7 ± 8.2 years and 48.8 ± 9.1 years in Group A and Group B respectively with a male predominance in both the groups. Patients in group A had higher BMI ≥25 and waist to height ratio (≥0.55) than Group B which showed a statistically significant asso...","downloadable_attachments":[{"id":81157848,"asset_id":72086800,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":27477844,"first_name":"khandker Md","last_name":"Nurus Sabah","domain_name":"independent","page_name":"khandkerMdNurusSabah","display_name":"khandker Md Nurus Sabah","profile_url":"https://independent.academia.edu/khandkerMdNurusSabah?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":18895,"name":"Bangladesh","url":"https://www.academia.edu/Documents/in/Bangladesh?f_ri=620049","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=620049","nofollow":true},{"id":41482,"name":"Multivariate Analysis","url":"https://www.academia.edu/Documents/in/Multivariate_Analysis?f_ri=620049","nofollow":true},{"id":192564,"name":"Body Mass Index","url":"https://www.academia.edu/Documents/in/Body_Mass_Index?f_ri=620049","nofollow":true},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":227297,"name":"Waist Circumference","url":"https://www.academia.edu/Documents/in/Waist_Circumference?f_ri=620049"},{"id":374984,"name":"Coronary Angiography","url":"https://www.academia.edu/Documents/in/Coronary_Angiography?f_ri=620049"},{"id":489727,"name":"Prognosis","url":"https://www.academia.edu/Documents/in/Prognosis?f_ri=620049"},{"id":568482,"name":"Biological markers","url":"https://www.academia.edu/Documents/in/Biological_markers?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":789977,"name":"Coronary Artery Disease","url":"https://www.academia.edu/Documents/in/Coronary_Artery_Disease?f_ri=620049"},{"id":892682,"name":"Body Height","url":"https://www.academia.edu/Documents/in/Body_Height?f_ri=620049"},{"id":1034181,"name":"Cross Sectional Studies","url":"https://www.academia.edu/Documents/in/Cross_Sectional_Studies?f_ri=620049"},{"id":2463800,"name":"Severity of Illness Index","url":"https://www.academia.edu/Documents/in/Severity_of_Illness_Index?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_11009168" data-work_id="11009168" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/11009168/Local_recurrence_after_endoscopic_mucosal_resection_of_nonpedunculated_colorectal_lesions_systematic_review_and_meta_analysis">Local recurrence after endoscopic mucosal resection of nonpedunculated colorectal lesions: systematic review and meta-analysis</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Removal of colorectal adenomas during colonoscopy reduces the incidence of colorectal carcinoma (CRC) and CRC-related mortality [1 -4]. Despite surveillance of patients after resection of adenomas [5] the risk of developing CRC remains... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_11009168" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Removal of colorectal adenomas during colonoscopy reduces the incidence of colorectal carcinoma (CRC) and CRC-related mortality [1 -4]. Despite surveillance of patients after resection of adenomas [5] the risk of developing CRC remains higher than in the general population [6]. Moreover, it is known that CRC can be detected in the interval between scheduled surveillance colonoscopies [7]. One of the important causes for interval carcinomas is incomplete removal of the original adenoma [8 -10]. As residual adenomatous tissue has been shown to be capable of rapid regeneration , incomplete resection may result in local recurrence . Several studies have indicated that incomplete removal contributes to a higher subsequent incidence of CRC [5, 9, 14 -16].</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/11009168" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="6dff018c61e0890f4b6f5b55851cd64b" rel="nofollow" data-download="{"attachment_id":36737595,"asset_id":11009168,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/36737595/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="26652959" href="https://uu.academia.edu/MaxLeenders">Max Leenders</a><script data-card-contents-for-user="26652959" type="text/json">{"id":26652959,"first_name":"Max","last_name":"Leenders","domain_name":"uu","page_name":"MaxLeenders","display_name":"Max Leenders","profile_url":"https://uu.academia.edu/MaxLeenders?f_ri=620049","photo":"https://0.academia-photos.com/26652959/7421583/8341757/s65_max.leenders.jpg"}</script></span></span></li><li class="js-paper-rank-work_11009168 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="11009168"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 11009168, container: ".js-paper-rank-work_11009168", }); });</script></li><li class="js-percentile-work_11009168 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 11009168; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_11009168"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_11009168 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="11009168"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 11009168; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=11009168]").text(description); $(".js-view-count-work_11009168").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_11009168").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="11009168"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="3274" rel="nofollow" href="https://www.academia.edu/Documents/in/Gastroenterology">Gastroenterology</a>, <script data-card-contents-for-ri="3274" type="text/json">{"id":3274,"name":"Gastroenterology","url":"https://www.academia.edu/Documents/in/Gastroenterology?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="37805" rel="nofollow" href="https://www.academia.edu/Documents/in/Endoscopy">Endoscopy</a>, <script data-card-contents-for-ri="37805" type="text/json">{"id":37805,"name":"Endoscopy","url":"https://www.academia.edu/Documents/in/Endoscopy?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="71471" rel="nofollow" href="https://www.academia.edu/Documents/in/Intestinal_Mucosa">Intestinal Mucosa</a>, <script data-card-contents-for-ri="71471" type="text/json">{"id":71471,"name":"Intestinal Mucosa","url":"https://www.academia.edu/Documents/in/Intestinal_Mucosa?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="77936" rel="nofollow" href="https://www.academia.edu/Documents/in/Text">Text</a><script data-card-contents-for-ri="77936" type="text/json">{"id":77936,"name":"Text","url":"https://www.academia.edu/Documents/in/Text?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=11009168]'), work: {"id":11009168,"title":"Local recurrence after endoscopic mucosal resection of nonpedunculated colorectal lesions: systematic review and meta-analysis","created_at":"2015-02-23T03:29:14.738-08:00","url":"https://www.academia.edu/11009168/Local_recurrence_after_endoscopic_mucosal_resection_of_nonpedunculated_colorectal_lesions_systematic_review_and_meta_analysis?f_ri=620049","dom_id":"work_11009168","summary":"Removal of colorectal adenomas during colonoscopy reduces the incidence of colorectal carcinoma (CRC) and CRC-related mortality [1 -4]. Despite surveillance of patients after resection of adenomas [5] the risk of developing CRC remains higher than in the general population [6]. Moreover, it is known that CRC can be detected in the interval between scheduled surveillance colonoscopies [7]. One of the important causes for interval carcinomas is incomplete removal of the original adenoma [8 -10]. As residual adenomatous tissue has been shown to be capable of rapid regeneration , incomplete resection may result in local recurrence . Several studies have indicated that incomplete removal contributes to a higher subsequent incidence of CRC [5, 9, 14 -16].","downloadable_attachments":[{"id":36737595,"asset_id":11009168,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":26652959,"first_name":"Max","last_name":"Leenders","domain_name":"uu","page_name":"MaxLeenders","display_name":"Max Leenders","profile_url":"https://uu.academia.edu/MaxLeenders?f_ri=620049","photo":"https://0.academia-photos.com/26652959/7421583/8341757/s65_max.leenders.jpg"}],"research_interests":[{"id":3274,"name":"Gastroenterology","url":"https://www.academia.edu/Documents/in/Gastroenterology?f_ri=620049","nofollow":true},{"id":37805,"name":"Endoscopy","url":"https://www.academia.edu/Documents/in/Endoscopy?f_ri=620049","nofollow":true},{"id":71471,"name":"Intestinal Mucosa","url":"https://www.academia.edu/Documents/in/Intestinal_Mucosa?f_ri=620049","nofollow":true},{"id":77936,"name":"Text","url":"https://www.academia.edu/Documents/in/Text?f_ri=620049","nofollow":true},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":227324,"name":"Colonoscopy","url":"https://www.academia.edu/Documents/in/Colonoscopy?f_ri=620049"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":2440562,"name":"Colorectal Neoplasms","url":"https://www.academia.edu/Documents/in/Colorectal_Neoplasms?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_48776188" data-work_id="48776188" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/48776188/Family_homelessness_state_or_trait">Family homelessness: state or trait?</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Compares conceptualizations of homelessness as a temporary state through which people pass or a permanent trait that emanates from individual characteristics. Evidence from a longitudinal study of 564 homeless families in New York City... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_48776188" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Compares conceptualizations of homelessness as a temporary state through which people pass or a permanent trait that emanates from individual characteristics. Evidence from a longitudinal study of 564 homeless families in New York City and additional secondary sources supports the view that for families, homelessness is a temporary state that is resolved by the provision of subsidized housing. Even for single individuals with severe mental disturbances, housing is a key factor in ending homelessness, although here there is more evidence that social services also contribute. Policy implications are that governments should take a more active role in reducing homelessness by providing access to subsidized housing.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/48776188" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="2a92f540011ea18a9c30a35fa9838ad6" rel="nofollow" data-download="{"attachment_id":67217900,"asset_id":48776188,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/67217900/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="38791186" href="https://independent.academia.edu/MarybethShinn">Marybeth Shinn</a><script data-card-contents-for-user="38791186" type="text/json">{"id":38791186,"first_name":"Marybeth","last_name":"Shinn","domain_name":"independent","page_name":"MarybethShinn","display_name":"Marybeth Shinn","profile_url":"https://independent.academia.edu/MarybethShinn?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_48776188 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="48776188"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 48776188, container: ".js-paper-rank-work_48776188", }); 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Evidence from a longitudinal study of 564 homeless families in New York City and additional secondary sources supports the view that for families, homelessness is a temporary state that is resolved by the provision of subsidized housing. Even for single individuals with severe mental disturbances, housing is a key factor in ending homelessness, although here there is more evidence that social services also contribute. Policy implications are that governments should take a more active role in reducing homelessness by providing access to subsidized housing.","downloadable_attachments":[{"id":67217900,"asset_id":48776188,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":38791186,"first_name":"Marybeth","last_name":"Shinn","domain_name":"independent","page_name":"MarybethShinn","display_name":"Marybeth Shinn","profile_url":"https://independent.academia.edu/MarybethShinn?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":202,"name":"Program Evaluation","url":"https://www.academia.edu/Documents/in/Program_Evaluation?f_ri=620049","nofollow":true},{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=620049","nofollow":true},{"id":940,"name":"Social 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href="https://www.academia.edu/14137487/Post_traumatic_stress_disorder_in_the_community_an_epidemiological_study">Post-traumatic stress disorder in the community: an epidemiological study</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/14137487" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="af33118dd099df79a37a891c4549b043" rel="nofollow" data-download="{"attachment_id":44570579,"asset_id":14137487,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm 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Studies","url":"https://www.academia.edu/Documents/in/Epidemiologic_Studies?f_ri=620049"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_25911631" data-work_id="25911631" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/25911631/Who_needs_antipsychotic_medication_in_the_earliest_stages_of_psychosis_A_reconsideration_of_benefits_risks_neurobiology_and_ethics_in_the_era_of_early_intervention">Who needs antipsychotic medication in the earliest stages of psychosis? A reconsideration of benefits, risks, neurobiology and ethics in the era of early intervention</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/25911631" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="98d5a1e0671f57a2b210ae190672c4f8" rel="nofollow" data-download="{"attachment_id":46273885,"asset_id":25911631,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46273885/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="4452479" href="https://unimelb.academia.edu/SusyHarrigan">Susy Harrigan</a><script data-card-contents-for-user="4452479" type="text/json">{"id":4452479,"first_name":"Susy","last_name":"Harrigan","domain_name":"unimelb","page_name":"SusyHarrigan","display_name":"Susy Harrigan","profile_url":"https://unimelb.academia.edu/SusyHarrigan?f_ri=620049","photo":"https://0.academia-photos.com/4452479/1820373/35640029/s65_susy.harrigan.jpeg"}</script></span></span></li><li class="js-paper-rank-work_25911631 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="25911631"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 25911631, container: ".js-paper-rank-work_25911631", }); 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This literature review proposes an integrative model based on empirical data on... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_15387410" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Dyssomnias Sleep duration Early childhood Risk factors Consequences Model s u m m a r y Dyssomnias are largely under-diagnosed in infants and toddlers. This literature review proposes an integrative model based on empirical data on determinants and consequences of sleep disturbances occurring in early life. This model proposes that parental behaviors that impede the child's autonomy toward sleep periods are primary grounds for the development of dyssomnias, e.g., parental presence until the child falls asleep, and putting an already sleeping child to bed. The model also indicates the serious potential consequences of a modest but chronic loss of sleep in childhood. At least three developmental domains could be directly affected: behavioral/social competence, cognitive performance, and physical condition. Thus, children with short nocturnal sleep duration before age 3.5 years show increased risk of high hyperactivity-impulsivity scores and low cognitive performance at 6 years compared to children who sleep 11 h per night, after controlling for potentially confounding variables. Moreover, persistent short sleep duration in early infancy increased the risk of suffering of obesity at 6 years of age, after controlling for potentially confounding variables. Finally, the importance of allowing the child to sleep at least 10 h per night in early childhood is stressed, as the National Sleep Foundation Poll suggests, for optimal child development.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/15387410" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="c221b338a47c42e013e61327b5e42413" rel="nofollow" data-download="{"attachment_id":43238607,"asset_id":15387410,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/43238607/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="34535874" href="https://independent.academia.edu/EvelyneTouchette">Evelyne Touchette</a><script data-card-contents-for-user="34535874" type="text/json">{"id":34535874,"first_name":"Evelyne","last_name":"Touchette","domain_name":"independent","page_name":"EvelyneTouchette","display_name":"Evelyne Touchette","profile_url":"https://independent.academia.edu/EvelyneTouchette?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_15387410 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="15387410"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 15387410, container: ".js-paper-rank-work_15387410", }); 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$(".js-view-count[data-work-id=15387410]").text(description); $(".js-view-count-work_15387410").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_15387410").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="15387410"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">12</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="4583" rel="nofollow" href="https://www.academia.edu/Documents/in/Child_Development">Child Development</a>, <script data-card-contents-for-ri="4583" type="text/json">{"id":4583,"name":"Child Development","url":"https://www.academia.edu/Documents/in/Child_Development?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="30140" rel="nofollow" href="https://www.academia.edu/Documents/in/Early_Childhood">Early Childhood</a>, <script data-card-contents-for-ri="30140" type="text/json">{"id":30140,"name":"Early Childhood","url":"https://www.academia.edu/Documents/in/Early_Childhood?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="64933" rel="nofollow" href="https://www.academia.edu/Documents/in/Child">Child</a>, <script data-card-contents-for-ri="64933" type="text/json">{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="89121" rel="nofollow" href="https://www.academia.edu/Documents/in/Circadian_Rhythm">Circadian Rhythm</a><script data-card-contents-for-ri="89121" type="text/json">{"id":89121,"name":"Circadian Rhythm","url":"https://www.academia.edu/Documents/in/Circadian_Rhythm?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=15387410]'), work: {"id":15387410,"title":"Risk factors and consequences of early childhood dyssomnias: New perspectives","created_at":"2015-09-04T04:53:57.952-07:00","url":"https://www.academia.edu/15387410/Risk_factors_and_consequences_of_early_childhood_dyssomnias_New_perspectives?f_ri=620049","dom_id":"work_15387410","summary":"Dyssomnias Sleep duration Early childhood Risk factors Consequences Model s u m m a r y Dyssomnias are largely under-diagnosed in infants and toddlers. This literature review proposes an integrative model based on empirical data on determinants and consequences of sleep disturbances occurring in early life. This model proposes that parental behaviors that impede the child's autonomy toward sleep periods are primary grounds for the development of dyssomnias, e.g., parental presence until the child falls asleep, and putting an already sleeping child to bed. The model also indicates the serious potential consequences of a modest but chronic loss of sleep in childhood. At least three developmental domains could be directly affected: behavioral/social competence, cognitive performance, and physical condition. Thus, children with short nocturnal sleep duration before age 3.5 years show increased risk of high hyperactivity-impulsivity scores and low cognitive performance at 6 years compared to children who sleep 11 h per night, after controlling for potentially confounding variables. Moreover, persistent short sleep duration in early infancy increased the risk of suffering of obesity at 6 years of age, after controlling for potentially confounding variables. Finally, the importance of allowing the child to sleep at least 10 h per night in early childhood is stressed, as the National Sleep Foundation Poll suggests, for optimal child development.","downloadable_attachments":[{"id":43238607,"asset_id":15387410,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":34535874,"first_name":"Evelyne","last_name":"Touchette","domain_name":"independent","page_name":"EvelyneTouchette","display_name":"Evelyne Touchette","profile_url":"https://independent.academia.edu/EvelyneTouchette?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":4583,"name":"Child Development","url":"https://www.academia.edu/Documents/in/Child_Development?f_ri=620049","nofollow":true},{"id":30140,"name":"Early Childhood","url":"https://www.academia.edu/Documents/in/Early_Childhood?f_ri=620049","nofollow":true},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=620049","nofollow":true},{"id":89121,"name":"Circadian Rhythm","url":"https://www.academia.edu/Documents/in/Circadian_Rhythm?f_ri=620049","nofollow":true},{"id":106431,"name":"Sleep disorders","url":"https://www.academia.edu/Documents/in/Sleep_disorders?f_ri=620049"},{"id":133324,"name":"Sleep","url":"https://www.academia.edu/Documents/in/Sleep?f_ri=620049"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=620049"},{"id":137145,"name":"Developmental disabilities","url":"https://www.academia.edu/Documents/in/Developmental_disabilities?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":289330,"name":"Prevalence","url":"https://www.academia.edu/Documents/in/Prevalence?f_ri=620049"},{"id":303598,"name":"Parents","url":"https://www.academia.edu/Documents/in/Parents?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_13297927" data-work_id="13297927" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13297927/Visual_Symptoms_and_Retinal_Straylight_after_Laser_Peripheral_Iridotomy_The_Zhongshan_Angle_Closure_Prevention_Trial">Visual Symptoms and Retinal Straylight after Laser Peripheral Iridotomy: The Zhongshan Angle-Closure Prevention Trial</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">OBJECTIVE: To assess the impact of laser peripheral iridotomy (LPI) on forward-scatter of light and subjective visual symptoms and to identify LPI parameters influencing these phenomena. DESIGN: Cohort study derived from a randomized... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_13297927" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">OBJECTIVE: To assess the impact of laser peripheral iridotomy (LPI) on forward-scatter of light and subjective visual symptoms and to identify LPI parameters influencing these phenomena. DESIGN: Cohort study derived from a randomized trial, using an external control group. PARTICIPANTS: Chinese subjects initially aged 50 or older and 70 years or younger with bilateral narrow angles undergoing LPI in 1 eye selected at random, and age- and gender-matched controls. METHODS: Eighteen months after laser, LPI-treated subjects underwent digital iris photography and photogrammetry to characterize the size and location of the LPI, Lens Opacity Classification System III cataract grading, and measurement of retinal straylight (C-Quant; OCULUS, Wetzlar, Germany) in the treated and untreated eyes and completed a visual symptoms questionnaire. Controls answered the questionnaire and underwent straylight measurement and (in a random one-sixth sample) cataract grading. MAIN OUTCOME MEASURES: Retina...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13297927" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="74c98f5473a9ea161d74198f8a3bf8bf" rel="nofollow" data-download="{"attachment_id":45497790,"asset_id":13297927,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45497790/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32547541" href="https://qub.academia.edu/NathanCongdon">Nathan Congdon</a><script data-card-contents-for-user="32547541" type="text/json">{"id":32547541,"first_name":"Nathan","last_name":"Congdon","domain_name":"qub","page_name":"NathanCongdon","display_name":"Nathan Congdon","profile_url":"https://qub.academia.edu/NathanCongdon?f_ri=620049","photo":"https://0.academia-photos.com/32547541/80338835/68916862/s65_nathan.congdon.jpeg"}</script></span></span></li><li class="js-paper-rank-work_13297927 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="13297927"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 13297927, container: ".js-paper-rank-work_13297927", }); 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$(".js-view-count[data-work-id=13297927]").text(description); $(".js-view-count-work_13297927").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_13297927").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="13297927"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">19</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="627" rel="nofollow" href="https://www.academia.edu/Documents/in/Ophthalmology">Ophthalmology</a>, <script data-card-contents-for-ri="627" type="text/json">{"id":627,"name":"Ophthalmology","url":"https://www.academia.edu/Documents/in/Ophthalmology?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="15851" rel="nofollow" href="https://www.academia.edu/Documents/in/Solid_state_lasers">Solid state lasers</a>, <script data-card-contents-for-ri="15851" type="text/json">{"id":15851,"name":"Solid state lasers","url":"https://www.academia.edu/Documents/in/Solid_state_lasers?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="40271" rel="nofollow" href="https://www.academia.edu/Documents/in/Visual_acuity">Visual acuity</a>, <script data-card-contents-for-ri="40271" type="text/json">{"id":40271,"name":"Visual acuity","url":"https://www.academia.edu/Documents/in/Visual_acuity?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="117200" rel="nofollow" href="https://www.academia.edu/Documents/in/Retina">Retina</a><script data-card-contents-for-ri="117200" type="text/json">{"id":117200,"name":"Retina","url":"https://www.academia.edu/Documents/in/Retina?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=13297927]'), work: {"id":13297927,"title":"Visual Symptoms and Retinal Straylight after Laser Peripheral Iridotomy: The Zhongshan Angle-Closure Prevention Trial","created_at":"2015-06-25T19:54:11.669-07:00","url":"https://www.academia.edu/13297927/Visual_Symptoms_and_Retinal_Straylight_after_Laser_Peripheral_Iridotomy_The_Zhongshan_Angle_Closure_Prevention_Trial?f_ri=620049","dom_id":"work_13297927","summary":"OBJECTIVE: To assess the impact of laser peripheral iridotomy (LPI) on forward-scatter of light and subjective visual symptoms and to identify LPI parameters influencing these phenomena. DESIGN: Cohort study derived from a randomized trial, using an external control group. PARTICIPANTS: Chinese subjects initially aged 50 or older and 70 years or younger with bilateral narrow angles undergoing LPI in 1 eye selected at random, and age- and gender-matched controls. METHODS: Eighteen months after laser, LPI-treated subjects underwent digital iris photography and photogrammetry to characterize the size and location of the LPI, Lens Opacity Classification System III cataract grading, and measurement of retinal straylight (C-Quant; OCULUS, Wetzlar, Germany) in the treated and untreated eyes and completed a visual symptoms questionnaire. Controls answered the questionnaire and underwent straylight measurement and (in a random one-sixth sample) cataract grading. MAIN OUTCOME MEASURES: Retina...","downloadable_attachments":[{"id":45497790,"asset_id":13297927,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32547541,"first_name":"Nathan","last_name":"Congdon","domain_name":"qub","page_name":"NathanCongdon","display_name":"Nathan Congdon","profile_url":"https://qub.academia.edu/NathanCongdon?f_ri=620049","photo":"https://0.academia-photos.com/32547541/80338835/68916862/s65_nathan.congdon.jpeg"}],"research_interests":[{"id":627,"name":"Ophthalmology","url":"https://www.academia.edu/Documents/in/Ophthalmology?f_ri=620049","nofollow":true},{"id":15851,"name":"Solid state lasers","url":"https://www.academia.edu/Documents/in/Solid_state_lasers?f_ri=620049","nofollow":true},{"id":40271,"name":"Visual acuity","url":"https://www.academia.edu/Documents/in/Visual_acuity?f_ri=620049","nofollow":true},{"id":117200,"name":"Retina","url":"https://www.academia.edu/Documents/in/Retina?f_ri=620049","nofollow":true},{"id":121320,"name":"Intraocular Pressure","url":"https://www.academia.edu/Documents/in/Intraocular_Pressure?f_ri=620049"},{"id":128057,"name":"Light","url":"https://www.academia.edu/Documents/in/Light?f_ri=620049"},{"id":166456,"name":"Glare","url":"https://www.academia.edu/Documents/in/Glare?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=620049"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=620049"},{"id":327850,"name":"Questionnaires","url":"https://www.academia.edu/Documents/in/Questionnaires?f_ri=620049"},{"id":359001,"name":"Optometry and Ophthalmology","url":"https://www.academia.edu/Documents/in/Optometry_and_Ophthalmology?f_ri=620049"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=620049"},{"id":469022,"name":"Vision Disorders","url":"https://www.academia.edu/Documents/in/Vision_Disorders?f_ri=620049"},{"id":591484,"name":"Laser Therapy","url":"https://www.academia.edu/Documents/in/Laser_Therapy?f_ri=620049"},{"id":619723,"name":"Iris","url":"https://www.academia.edu/Documents/in/Iris?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":990525,"name":"Retinal Diseases","url":"https://www.academia.edu/Documents/in/Retinal_Diseases?f_ri=620049"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_23215110" data-work_id="23215110" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/23215110/Vitamin_D_status_and_response_to_treatment_in_post_menopausal_osteoporosis">Vitamin D status and response to treatment in post-menopausal osteoporosis</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Treatment with anti-resorptive agents over 13 months was associated with for three to fivefold lower bone mineral density changes and 1.5-fold increased risk of incidence fracture in vitamin D insufficient as compared to vitamin D... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_23215110" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Treatment with anti-resorptive agents over 13 months was associated with for three to fivefold lower bone mineral density changes and 1.5-fold increased risk of incidence fracture in vitamin D insufficient as compared to vitamin D repleted postmenopausal osteoporotic women. Introduction Several drugs were registered for the treatment of osteoporosis on the basis of clinical trials in which vitamin D repletion was a pre-requisite inclusion criteria and vitamin D supplements were used as adjunctive therapy. However, in routine clinical practice these supplements are not consistently recommended. Methods We studied 1515 women with postmenopausal osteoporosis under treatment with anti-resorbing agents (alendronate, risedronate, raloxifene) for 13.1 months with an adherence > 75%. The patients were classified as vitamin D deficient (N=514) or vitamin D repleted (N=1001) according to risk factors (N=1062) or the level of 25(OH) vitamin D [25(OH)D] above or below 50 nmol/l (N=453). Results Vitamin D deficient and vitamin D repleted subjects differed significantly for annualized spine and hip bone mineral density (BMD) changes adjusted for all available confounding factors (type of treatment, age, global calcium intake, baseline BMD values). One hundred fifty one patients suffered from a new incident clinical fracture. The adjusted odds ratio for incident fractures in vitamin D deficient as compared to vitamin D repleted women was 1.77 (1.20 -2.59, 95% CI; p=0.004). Conclusions Optimal vitamin D repletion seems to be necessary to maximize the response to anti-resorbers in terms of both BMD changes and anti-fracture efficacy.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/23215110" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a9ccfad5854ca60989d4994b19f1eee2" rel="nofollow" data-download="{"attachment_id":43704884,"asset_id":23215110,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/43704884/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="45058036" href="https://independent.academia.edu/GerolamoBianchi">Gerolamo Bianchi</a><script data-card-contents-for-user="45058036" type="text/json">{"id":45058036,"first_name":"Gerolamo","last_name":"Bianchi","domain_name":"independent","page_name":"GerolamoBianchi","display_name":"Gerolamo Bianchi","profile_url":"https://independent.academia.edu/GerolamoBianchi?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_23215110 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="23215110"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 23215110, container: ".js-paper-rank-work_23215110", }); 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$(".js-view-count[data-work-id=23215110]").text(description); $(".js-view-count-work_23215110").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_23215110").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="23215110"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">24</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="4531" rel="nofollow" href="https://www.academia.edu/Documents/in/Clinical_Trial">Clinical Trial</a>, <script data-card-contents-for-ri="4531" type="text/json">{"id":4531,"name":"Clinical Trial","url":"https://www.academia.edu/Documents/in/Clinical_Trial?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="8207" rel="nofollow" href="https://www.academia.edu/Documents/in/Risk">Risk</a>, <script data-card-contents-for-ri="8207" type="text/json">{"id":8207,"name":"Risk","url":"https://www.academia.edu/Documents/in/Risk?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="9531" rel="nofollow" href="https://www.academia.edu/Documents/in/Vitamin_D">Vitamin D</a>, <script data-card-contents-for-ri="9531" type="text/json">{"id":9531,"name":"Vitamin D","url":"https://www.academia.edu/Documents/in/Vitamin_D?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="9534" rel="nofollow" href="https://www.academia.edu/Documents/in/Calcium">Calcium</a><script data-card-contents-for-ri="9534" type="text/json">{"id":9534,"name":"Calcium","url":"https://www.academia.edu/Documents/in/Calcium?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=23215110]'), work: {"id":23215110,"title":"Vitamin D status and response to treatment in post-menopausal osteoporosis","created_at":"2016-03-14T00:42:19.181-07:00","url":"https://www.academia.edu/23215110/Vitamin_D_status_and_response_to_treatment_in_post_menopausal_osteoporosis?f_ri=620049","dom_id":"work_23215110","summary":"Treatment with anti-resorptive agents over 13 months was associated with for three to fivefold lower bone mineral density changes and 1.5-fold increased risk of incidence fracture in vitamin D insufficient as compared to vitamin D repleted postmenopausal osteoporotic women. Introduction Several drugs were registered for the treatment of osteoporosis on the basis of clinical trials in which vitamin D repletion was a pre-requisite inclusion criteria and vitamin D supplements were used as adjunctive therapy. However, in routine clinical practice these supplements are not consistently recommended. Methods We studied 1515 women with postmenopausal osteoporosis under treatment with anti-resorbing agents (alendronate, risedronate, raloxifene) for 13.1 months with an adherence \u003e 75%. The patients were classified as vitamin D deficient (N=514) or vitamin D repleted (N=1001) according to risk factors (N=1062) or the level of 25(OH) vitamin D [25(OH)D] above or below 50 nmol/l (N=453). Results Vitamin D deficient and vitamin D repleted subjects differed significantly for annualized spine and hip bone mineral density (BMD) changes adjusted for all available confounding factors (type of treatment, age, global calcium intake, baseline BMD values). One hundred fifty one patients suffered from a new incident clinical fracture. The adjusted odds ratio for incident fractures in vitamin D deficient as compared to vitamin D repleted women was 1.77 (1.20 -2.59, 95% CI; p=0.004). Conclusions Optimal vitamin D repletion seems to be necessary to maximize the response to anti-resorbers in terms of both BMD changes and anti-fracture efficacy.","downloadable_attachments":[{"id":43704884,"asset_id":23215110,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":45058036,"first_name":"Gerolamo","last_name":"Bianchi","domain_name":"independent","page_name":"GerolamoBianchi","display_name":"Gerolamo Bianchi","profile_url":"https://independent.academia.edu/GerolamoBianchi?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":4531,"name":"Clinical Trial","url":"https://www.academia.edu/Documents/in/Clinical_Trial?f_ri=620049","nofollow":true},{"id":8207,"name":"Risk","url":"https://www.academia.edu/Documents/in/Risk?f_ri=620049","nofollow":true},{"id":9531,"name":"Vitamin D","url":"https://www.academia.edu/Documents/in/Vitamin_D?f_ri=620049","nofollow":true},{"id":9534,"name":"Calcium","url":"https://www.academia.edu/Documents/in/Calcium?f_ri=620049","nofollow":true},{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=620049"},{"id":44529,"name":"Activities of Daily Living","url":"https://www.academia.edu/Documents/in/Activities_of_Daily_Living?f_ri=620049"},{"id":52836,"name":"Clinical Practice","url":"https://www.academia.edu/Documents/in/Clinical_Practice?f_ri=620049"},{"id":63997,"name":"Osteoporosis","url":"https://www.academia.edu/Documents/in/Osteoporosis?f_ri=620049"},{"id":139532,"name":"Bone Density","url":"https://www.academia.edu/Documents/in/Bone_Density?f_ri=620049"},{"id":152562,"name":"Dietary Supplements","url":"https://www.academia.edu/Documents/in/Dietary_Supplements?f_ri=620049"},{"id":174502,"name":"Incidence","url":"https://www.academia.edu/Documents/in/Incidence?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=620049"},{"id":272426,"name":"Alendronate","url":"https://www.academia.edu/Documents/in/Alendronate?f_ri=620049"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=620049"},{"id":437772,"name":"Odds ratio","url":"https://www.academia.edu/Documents/in/Odds_ratio?f_ri=620049"},{"id":438516,"name":"Bone Mineral Density","url":"https://www.academia.edu/Documents/in/Bone_Mineral_Density?f_ri=620049"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=620049"},{"id":568482,"name":"Biological markers","url":"https://www.academia.edu/Documents/in/Biological_markers?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":1114577,"name":"Vitamin D Deficiency","url":"https://www.academia.edu/Documents/in/Vitamin_D_Deficiency?f_ri=620049"},{"id":1294607,"name":"Logistic Models","url":"https://www.academia.edu/Documents/in/Logistic_Models?f_ri=620049"},{"id":1399820,"name":"Bone Resorption","url":"https://www.academia.edu/Documents/in/Bone_Resorption?f_ri=620049"},{"id":2366479,"name":"Raloxifene","url":"https://www.academia.edu/Documents/in/Raloxifene?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_8424364" data-work_id="8424364" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/8424364/Fractures_in_infants_and_toddlers_with_rickets">Fractures in infants and toddlers with rickets</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Background Rickets affects young infants and toddlers. However, there is a paucity of literature regarding the types of fractures that occur in rachitic patients. Objective To evaluate the age of patients at which radiographically evident... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_8424364" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Background Rickets affects young infants and toddlers. However, there is a paucity of literature regarding the types of fractures that occur in rachitic patients. Objective To evaluate the age of patients at which radiographically evident rickets occurs, and to characterize the age incidence and fractures that are observed in infants and toddlers with radiographically evident rickets. Materials and methods A retrospective study of children younger than 24 months was performed. Clinical data and radiographs were reviewed. Radiographs obtained within 1 month of the diagnosis were evaluated for the presence or absence of osteopenia, presence or absence of fraying–cupping, and presence and characterization of fractures. Results After exclusion criteria were applied, 45 children were included in the study. Children with rickets evident by radiograph were in the age range of 2–24 months. Fractures were present in 17.5% of the study group, exclusively in mobile infants and toddlers. Fracture types included transverse long bone fractures, anterior and anterior-lateral rib fractures, and metaphyseal fractures. All fractures occurred exclusively in patients with severe, overtly evident rickets. Conclusion Fractures occur in older infants and toddlers with overt rickets and can be seen by radiograph. Fractures do not resemble high-risk non-accidental trauma fractures.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/8424364" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="fc942672b4036be805d3d208de4a7571" rel="nofollow" data-download="{"attachment_id":48100890,"asset_id":8424364,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48100890/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="17080389" href="https://washington.academia.edu/NicolleWambold">Nicolle Wambold</a><script data-card-contents-for-user="17080389" type="text/json">{"id":17080389,"first_name":"Nicolle","last_name":"Wambold","domain_name":"washington","page_name":"NicolleWambold","display_name":"Nicolle Wambold","profile_url":"https://washington.academia.edu/NicolleWambold?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_8424364 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="8424364"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 8424364, container: ".js-paper-rank-work_8424364", }); 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However, there is a paucity of literature regarding the types of fractures that occur in rachitic patients. Objective To evaluate the age of patients at which radiographically evident rickets occurs, and to characterize the age incidence and fractures that are observed in infants and toddlers with radiographically evident rickets. Materials and methods A retrospective study of children younger than 24 months was performed. Clinical data and radiographs were reviewed. Radiographs obtained within 1 month of the diagnosis were evaluated for the presence or absence of osteopenia, presence or absence of fraying–cupping, and presence and characterization of fractures. Results After exclusion criteria were applied, 45 children were included in the study. Children with rickets evident by radiograph were in the age range of 2–24 months. Fractures were present in 17.5% of the study group, exclusively in mobile infants and toddlers. Fracture types included transverse long bone fractures, anterior and anterior-lateral rib fractures, and metaphyseal fractures. All fractures occurred exclusively in patients with severe, overtly evident rickets. Conclusion Fractures occur in older infants and toddlers with overt rickets and can be seen by radiograph. Fractures do not resemble high-risk non-accidental trauma fractures.","downloadable_attachments":[{"id":48100890,"asset_id":8424364,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":17080389,"first_name":"Nicolle","last_name":"Wambold","domain_name":"washington","page_name":"NicolleWambold","display_name":"Nicolle Wambold","profile_url":"https://washington.academia.edu/NicolleWambold?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=620049","nofollow":true},{"id":28973,"name":"Comorbidity","url":"https://www.academia.edu/Documents/in/Comorbidity?f_ri=620049","nofollow":true},{"id":129806,"name":"Pediatric 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Cannabis remains the most commonly used drug in the UK among those who reported... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_27411051" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">With regard to THC (Δ 9 -tetrahydrocannabinol), the main psychoactive constituent identified in the plant Cannabis sativa L, several facts are indisputable. Cannabis remains the most commonly used drug in the UK among those who reported driving under the influence of illegal drugs in the previous 12 months. There is a significant dose-related decrement in driving performance following cannabis use; raised blood THC concentrations are significantly associated with increased traffic crash and death risk. When cannabis and alcohol are detected together, there is a greater risk to road safety than when either drug is used alone. Patterns of use are important when interpreting blood concentration data: Smoking infrequently a single cannabis cigarette leads to peak plasma THC concentrations (21-267 μg/L) causing acute intoxication. In habitual, daily users, plasma THC concentrations range from 1.0 to 11.0 μg/L and are maintained by sequestration of the drug from the tissues. These facts undoubtedly make setting thresholds for drug-driving legislation difficult but there is clearly a case for cannabis. Determining minimum blood THC concentrations at which a driver becomes sufficiently impaired to be unable to safely drive a vehicle is of particular concern given the increasing medicinal use of the drug. Internationally legislation for driving under the influence of drugs (DUID) is based on either a proof of impairment or a per se approach. For the latter this can be either zerotolerance or based on concentration limits such as those used for alcohol. The different approaches are considered against current scientific evidence.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/27411051" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="8d9020bddcc0055c4b0a6f03b98387d5" rel="nofollow" data-download="{"attachment_id":47667412,"asset_id":27411051,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/47667412/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="13015345" href="https://kcl.academia.edu/kimwolff">kim wolff</a><script data-card-contents-for-user="13015345" type="text/json">{"id":13015345,"first_name":"kim","last_name":"wolff","domain_name":"kcl","page_name":"kimwolff","display_name":"kim wolff","profile_url":"https://kcl.academia.edu/kimwolff?f_ri=620049","photo":"https://0.academia-photos.com/13015345/6471981/7319512/s65_kim.wolff.png"}</script></span></span></li><li class="js-paper-rank-work_27411051 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="27411051"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 27411051, container: ".js-paper-rank-work_27411051", }); 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$(".js-view-count[data-work-id=27411051]").text(description); $(".js-view-count-work_27411051").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_27411051").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="27411051"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">11</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="3097" rel="nofollow" href="https://www.academia.edu/Documents/in/Multiple_sclerosis">Multiple sclerosis</a>, <script data-card-contents-for-ri="3097" type="text/json">{"id":3097,"name":"Multiple sclerosis","url":"https://www.academia.edu/Documents/in/Multiple_sclerosis?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="52027" rel="nofollow" href="https://www.academia.edu/Documents/in/Phytotherapy">Phytotherapy</a>, <script data-card-contents-for-ri="52027" type="text/json">{"id":52027,"name":"Phytotherapy","url":"https://www.academia.edu/Documents/in/Phytotherapy?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="192721" rel="nofollow" href="https://www.academia.edu/Documents/in/Risk_factors">Risk factors</a>, <script data-card-contents-for-ri="192721" type="text/json">{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="238724" rel="nofollow" href="https://www.academia.edu/Documents/in/Cannabis">Cannabis</a><script data-card-contents-for-ri="238724" type="text/json">{"id":238724,"name":"Cannabis","url":"https://www.academia.edu/Documents/in/Cannabis?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=27411051]'), work: {"id":27411051,"title":"Cannabis use in patients with multiple sclerosis","created_at":"2016-07-31T04:46:11.038-07:00","url":"https://www.academia.edu/27411051/Cannabis_use_in_patients_with_multiple_sclerosis?f_ri=620049","dom_id":"work_27411051","summary":"With regard to THC (Δ 9 -tetrahydrocannabinol), the main psychoactive constituent identified in the plant Cannabis sativa L, several facts are indisputable. Cannabis remains the most commonly used drug in the UK among those who reported driving under the influence of illegal drugs in the previous 12 months. There is a significant dose-related decrement in driving performance following cannabis use; raised blood THC concentrations are significantly associated with increased traffic crash and death risk. When cannabis and alcohol are detected together, there is a greater risk to road safety than when either drug is used alone. Patterns of use are important when interpreting blood concentration data: Smoking infrequently a single cannabis cigarette leads to peak plasma THC concentrations (21-267 μg/L) causing acute intoxication. In habitual, daily users, plasma THC concentrations range from 1.0 to 11.0 μg/L and are maintained by sequestration of the drug from the tissues. These facts undoubtedly make setting thresholds for drug-driving legislation difficult but there is clearly a case for cannabis. Determining minimum blood THC concentrations at which a driver becomes sufficiently impaired to be unable to safely drive a vehicle is of particular concern given the increasing medicinal use of the drug. Internationally legislation for driving under the influence of drugs (DUID) is based on either a proof of impairment or a per se approach. For the latter this can be either zerotolerance or based on concentration limits such as those used for alcohol. The different approaches are considered against current scientific evidence.","downloadable_attachments":[{"id":47667412,"asset_id":27411051,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":13015345,"first_name":"kim","last_name":"wolff","domain_name":"kcl","page_name":"kimwolff","display_name":"kim wolff","profile_url":"https://kcl.academia.edu/kimwolff?f_ri=620049","photo":"https://0.academia-photos.com/13015345/6471981/7319512/s65_kim.wolff.png"}],"research_interests":[{"id":3097,"name":"Multiple sclerosis","url":"https://www.academia.edu/Documents/in/Multiple_sclerosis?f_ri=620049","nofollow":true},{"id":52027,"name":"Phytotherapy","url":"https://www.academia.edu/Documents/in/Phytotherapy?f_ri=620049","nofollow":true},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049","nofollow":true},{"id":238724,"name":"Cannabis","url":"https://www.academia.edu/Documents/in/Cannabis?f_ri=620049","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=620049"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=620049"},{"id":327850,"name":"Questionnaires","url":"https://www.academia.edu/Documents/in/Questionnaires?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":1200766,"name":"Drug Utilization","url":"https://www.academia.edu/Documents/in/Drug_Utilization?f_ri=620049"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=620049"},{"id":1907321,"name":"Marijuana abuse","url":"https://www.academia.edu/Documents/in/Marijuana_abuse?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_16499219 coauthored" data-work_id="16499219" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/16499219/Immobility_a_major_risk_factor_for_development_of_pressure_ulcers_among_adult_hospitalized_patients_a_prospective_study">Immobility - a major risk factor for development of pressure ulcers among adult hospitalized patients: a prospective study</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objective: To identify risk factors associated with pressure ulcer development among adult hospitalized medical and surgical patients. Design: A prospective comparative study including 530 adult patients from medical and surgical wards.... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_16499219" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objective: To identify risk factors associated with pressure ulcer development among adult hospitalized medical and surgical patients. Design: A prospective comparative study including 530 adult patients from medical and surgical wards. Registered Nurses made the data collection on admission and once a week for up to 12 weeks. The risk assessment scale used was the Risk Assessment Pressure Sore (RAPS) scale, including the following variables; general physical condition, activity, mobility, moisture, food intake, fluid intake, sensory perception, friction and shear, body temperature and serum albumin. Results: Sixty-two (11.7%) patients developed 85 pressure ulcers. The most common pressure ulcer was that of nonblanchable erythema. Patients who developed pressure ulcers were significantly older, hospitalized for a longer time, had lower scores on the total RAPS scale, had lower weight and lower diastolic blood pressure than nonpressure ulcer patients did. In the multiple logistic regression analyses using variables included in the RAPS scale immobility emerged as a strong risk factor. When adding remaining significant variables in the analyses, mobility, time of hospitalization, age, surgical treatment and weight were found to be risk factors for pressure ulcer development. Conclusion: It is confirmed that immobility is a risk factor of major importance for pressure ulcer development among adult hospitalized patients. The results also indicate that the RAPS scale may be useful for prediction of pressure ulcer development in clinical practice.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/16499219" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="6b8ed60c89e94ea04f43ac7c9ce04fff" rel="nofollow" data-download="{"attachment_id":42497281,"asset_id":16499219,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42497281/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="35729560" href="https://independent.academia.edu/LindgrenMargareta">Margareta Lindgren</a><script data-card-contents-for-user="35729560" type="text/json">{"id":35729560,"first_name":"Margareta","last_name":"Lindgren","domain_name":"independent","page_name":"LindgrenMargareta","display_name":"Margareta Lindgren","profile_url":"https://independent.academia.edu/LindgrenMargareta?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-16499219">+1</span><div class="hidden js-additional-users-16499219"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://liu-se.academia.edu/MatsFredrikson">Mats Fredrikson</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-16499219'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-16499219').html(); 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container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_16499219 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="16499219"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 16499219; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=16499219]").text(description); $(".js-view-count-work_16499219").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_16499219").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="16499219"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">19</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="588" rel="nofollow" href="https://www.academia.edu/Documents/in/Nursing">Nursing</a>, <script data-card-contents-for-ri="588" type="text/json">{"id":588,"name":"Nursing","url":"https://www.academia.edu/Documents/in/Nursing?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="16664" rel="nofollow" href="https://www.academia.edu/Documents/in/Risk_assessment">Risk assessment</a>, <script data-card-contents-for-ri="16664" type="text/json">{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="44529" rel="nofollow" href="https://www.academia.edu/Documents/in/Activities_of_Daily_Living">Activities of Daily Living</a>, <script data-card-contents-for-ri="44529" type="text/json">{"id":44529,"name":"Activities of Daily Living","url":"https://www.academia.edu/Documents/in/Activities_of_Daily_Living?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="44814" rel="nofollow" href="https://www.academia.edu/Documents/in/Sweden">Sweden</a><script data-card-contents-for-ri="44814" type="text/json">{"id":44814,"name":"Sweden","url":"https://www.academia.edu/Documents/in/Sweden?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=16499219]'), work: {"id":16499219,"title":"Immobility - a major risk factor for development of pressure ulcers among adult hospitalized patients: a prospective study","created_at":"2015-10-06T00:37:27.614-07:00","url":"https://www.academia.edu/16499219/Immobility_a_major_risk_factor_for_development_of_pressure_ulcers_among_adult_hospitalized_patients_a_prospective_study?f_ri=620049","dom_id":"work_16499219","summary":"Objective: To identify risk factors associated with pressure ulcer development among adult hospitalized medical and surgical patients. Design: A prospective comparative study including 530 adult patients from medical and surgical wards. Registered Nurses made the data collection on admission and once a week for up to 12 weeks. The risk assessment scale used was the Risk Assessment Pressure Sore (RAPS) scale, including the following variables; general physical condition, activity, mobility, moisture, food intake, fluid intake, sensory perception, friction and shear, body temperature and serum albumin. Results: Sixty-two (11.7%) patients developed 85 pressure ulcers. The most common pressure ulcer was that of nonblanchable erythema. Patients who developed pressure ulcers were significantly older, hospitalized for a longer time, had lower scores on the total RAPS scale, had lower weight and lower diastolic blood pressure than nonpressure ulcer patients did. In the multiple logistic regression analyses using variables included in the RAPS scale immobility emerged as a strong risk factor. When adding remaining significant variables in the analyses, mobility, time of hospitalization, age, surgical treatment and weight were found to be risk factors for pressure ulcer development. Conclusion: It is confirmed that immobility is a risk factor of major importance for pressure ulcer development among adult hospitalized patients. The results also indicate that the RAPS scale may be useful for prediction of pressure ulcer development in clinical practice.","downloadable_attachments":[{"id":42497281,"asset_id":16499219,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":35729560,"first_name":"Margareta","last_name":"Lindgren","domain_name":"independent","page_name":"LindgrenMargareta","display_name":"Margareta Lindgren","profile_url":"https://independent.academia.edu/LindgrenMargareta?f_ri=620049","photo":"/images/s65_no_pic.png"},{"id":36055279,"first_name":"Mats","last_name":"Fredrikson","domain_name":"liu-se","page_name":"MatsFredrikson","display_name":"Mats Fredrikson","profile_url":"https://liu-se.academia.edu/MatsFredrikson?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":588,"name":"Nursing","url":"https://www.academia.edu/Documents/in/Nursing?f_ri=620049","nofollow":true},{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=620049","nofollow":true},{"id":44529,"name":"Activities of Daily Living","url":"https://www.academia.edu/Documents/in/Activities_of_Daily_Living?f_ri=620049","nofollow":true},{"id":44814,"name":"Sweden","url":"https://www.academia.edu/Documents/in/Sweden?f_ri=620049","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=620049"},{"id":329158,"name":"Caring","url":"https://www.academia.edu/Documents/in/Caring?f_ri=620049"},{"id":413194,"name":"Analysis of Variance","url":"https://www.academia.edu/Documents/in/Analysis_of_Variance?f_ri=620049"},{"id":465839,"name":"Bed Rest","url":"https://www.academia.edu/Documents/in/Bed_Rest?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":622589,"name":"Risk Assessment","url":"https://www.academia.edu/Documents/in/Risk_Assessment-2?f_ri=620049"},{"id":687277,"name":"Pressure Ulcer","url":"https://www.academia.edu/Documents/in/Pressure_Ulcer?f_ri=620049"},{"id":784431,"name":"Nursing Assessment","url":"https://www.academia.edu/Documents/in/Nursing_Assessment?f_ri=620049"},{"id":854662,"name":"Inpatients","url":"https://www.academia.edu/Documents/in/Inpatients?f_ri=620049"},{"id":1154231,"name":"Immobilization","url":"https://www.academia.edu/Documents/in/Immobilization?f_ri=620049"},{"id":1294607,"name":"Logistic Models","url":"https://www.academia.edu/Documents/in/Logistic_Models?f_ri=620049"},{"id":1312754,"name":"Prospective Study","url":"https://www.academia.edu/Documents/in/Prospective_Study?f_ri=620049"},{"id":1318932,"name":"Predictive value of tests","url":"https://www.academia.edu/Documents/in/Predictive_value_of_tests?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_15863635" data-work_id="15863635" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/15863635/Suicidal_ideation_self_harm_and_attempted_suicide_Results_from_the_British_psychiatric_morbidity_survey_2000">Suicidal ideation, self-harm and attempted suicide: Results from the British psychiatric morbidity survey 2000</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div 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u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">A quality of care debate centers on whether pressure ulcers result from factors largely dependent on caregivers, or whether pressure ulcers result from factors associated with patient morbidity. A reduction in incidence, defined as the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_24182421" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">A quality of care debate centers on whether pressure ulcers result from factors largely dependent on caregivers, or whether pressure ulcers result from factors associated with patient morbidity. A reduction in incidence, defined as the development of a new pressure ulcer, is the focus of prevention strategies. Yet epidemiological data demonstrates a stability in the incidence of pressure ulcers despite drastic improvements in understanding of pressure ulcers, increased regulatory oversight, and improvements in technologies available for prevention of pressure ulcers. The explanation for this stable incidence of pressure ulcers includes a failure of known effective preventive treat-ment to be applied or the failure of prevention strategies to be effective in spite of being applied. No intervention strategy has been reported that consistently and reproducibly reduces the incidence of pressure ulcers to zero. The published data on prevention of pressure ulcers do not support an assumption that all pressure ulcers are preventable. An effective prevention strategy demonstrated to eliminate pressure ulcers across healthcare settings is lacking. (J Am Med Dir Assoc 2003; 4: S44-S48)</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/24182421" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="1a7707adb785520cf83048ffe04aea1c" rel="nofollow" data-download="{"attachment_id":44519877,"asset_id":24182421,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44519877/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="46614534" href="https://independent.academia.edu/JacobDimant">Jacob Dimant</a><script data-card-contents-for-user="46614534" type="text/json">{"id":46614534,"first_name":"Jacob","last_name":"Dimant","domain_name":"independent","page_name":"JacobDimant","display_name":"Jacob Dimant","profile_url":"https://independent.academia.edu/JacobDimant?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_24182421 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="24182421"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 24182421, container: ".js-paper-rank-work_24182421", }); 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$(".js-view-count[data-work-id=24182421]").text(description); $(".js-view-count-work_24182421").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_24182421").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="24182421"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">12</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="1907" rel="nofollow" href="https://www.academia.edu/Documents/in/Nutrition">Nutrition</a>, <script data-card-contents-for-ri="1907" type="text/json">{"id":1907,"name":"Nutrition","url":"https://www.academia.edu/Documents/in/Nutrition?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="8974" rel="nofollow" href="https://www.academia.edu/Documents/in/Quality_of_Mental_Health_Care">Quality of Mental Health Care</a>, <script data-card-contents-for-ri="8974" type="text/json">{"id":8974,"name":"Quality of Mental Health Care","url":"https://www.academia.edu/Documents/in/Quality_of_Mental_Health_Care?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="9745" rel="nofollow" href="https://www.academia.edu/Documents/in/Quality_Improvement">Quality Improvement</a>, <script data-card-contents-for-ri="9745" type="text/json">{"id":9745,"name":"Quality Improvement","url":"https://www.academia.edu/Documents/in/Quality_Improvement?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="90380" rel="nofollow" href="https://www.academia.edu/Documents/in/Nursing_Homes">Nursing Homes</a><script data-card-contents-for-ri="90380" type="text/json">{"id":90380,"name":"Nursing Homes","url":"https://www.academia.edu/Documents/in/Nursing_Homes?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=24182421]'), work: {"id":24182421,"title":"Are All Pressure Ulcers Avoidable?","created_at":"2016-04-07T14:04:36.597-07:00","url":"https://www.academia.edu/24182421/Are_All_Pressure_Ulcers_Avoidable?f_ri=620049","dom_id":"work_24182421","summary":"A quality of care debate centers on whether pressure ulcers result from factors largely dependent on caregivers, or whether pressure ulcers result from factors associated with patient morbidity. A reduction in incidence, defined as the development of a new pressure ulcer, is the focus of prevention strategies. Yet epidemiological data demonstrates a stability in the incidence of pressure ulcers despite drastic improvements in understanding of pressure ulcers, increased regulatory oversight, and improvements in technologies available for prevention of pressure ulcers. The explanation for this stable incidence of pressure ulcers includes a failure of known effective preventive treat-ment to be applied or the failure of prevention strategies to be effective in spite of being applied. No intervention strategy has been reported that consistently and reproducibly reduces the incidence of pressure ulcers to zero. The published data on prevention of pressure ulcers do not support an assumption that all pressure ulcers are preventable. An effective prevention strategy demonstrated to eliminate pressure ulcers across healthcare settings is lacking. (J Am Med Dir Assoc 2003; 4: S44-S48)","downloadable_attachments":[{"id":44519877,"asset_id":24182421,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":46614534,"first_name":"Jacob","last_name":"Dimant","domain_name":"independent","page_name":"JacobDimant","display_name":"Jacob Dimant","profile_url":"https://independent.academia.edu/JacobDimant?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":1907,"name":"Nutrition","url":"https://www.academia.edu/Documents/in/Nutrition?f_ri=620049","nofollow":true},{"id":8974,"name":"Quality of Mental Health Care","url":"https://www.academia.edu/Documents/in/Quality_of_Mental_Health_Care?f_ri=620049","nofollow":true},{"id":9745,"name":"Quality Improvement","url":"https://www.academia.edu/Documents/in/Quality_Improvement?f_ri=620049","nofollow":true},{"id":90380,"name":"Nursing Homes","url":"https://www.academia.edu/Documents/in/Nursing_Homes?f_ri=620049","nofollow":true},{"id":98134,"name":"United States","url":"https://www.academia.edu/Documents/in/United_States?f_ri=620049"},{"id":174502,"name":"Incidence","url":"https://www.academia.edu/Documents/in/Incidence?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=620049"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=620049"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":687277,"name":"Pressure Ulcer","url":"https://www.academia.edu/Documents/in/Pressure_Ulcer?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_15433595 coauthored" data-work_id="15433595" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/15433595/How_Do_Police_Respond_to_Stalking_An_Examination_of_the_Risk_Management_Strategies_and_Tactics_Used_in_a_Specialized_Anti_Stalking_Law_Enforcement_Unit">How Do Police Respond to Stalking? An Examination of the Risk Management Strategies and Tactics Used in a Specialized Anti-Stalking Law Enforcement Unit</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">How do police respond to and manage complaints of stalking? To answer this question, we conducted a 3-phase study. First, we reviewed the literature to identify risk management tactics used to combat stalking. Second, we asked a group of... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_15433595" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">How do police respond to and manage complaints of stalking? To answer this question, we conducted a 3-phase study. First, we reviewed the literature to identify risk management tactics used to combat stalking. Second, we asked a group of police officers to review those tactics for completeness and group them into categories reflecting more general risk management strategies. The result was 22 categories of strategies. Finally, we used qualitative methods to evaluate the files of 32 cases referred to the specialized anti-stalking unit of a metropolitan police department. We coded specific risk management tactics and strategies used by police. Results indicated that a median number of 19 specific tactics from 7 general strategies were used to manage risk. Also, the implementation of strategies and tactics reflected specific characteristics of the cases (e.g., perpetrator risk factors, victim vulnerability factors), suggesting that the risk management decisions made by police were indeed strategic in nature. Qualitative analyses indicated that some of the strategies and tactics were more effective than others. We discuss how these findings can be used to understand and use stalking risk management more generally, as well as improve research on the efficacy of risk assessment and management for stalking.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/15433595" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="73aaafc52c7d8d4988928a51b2c6c8f4" rel="nofollow" data-download="{"attachment_id":43203410,"asset_id":15433595,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/43203410/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="34690978" href="https://independent.academia.edu/JStorey1">J. Storey</a><script data-card-contents-for-user="34690978" type="text/json">{"id":34690978,"first_name":"J.","last_name":"Storey","domain_name":"independent","page_name":"JStorey1","display_name":"J. Storey","profile_url":"https://independent.academia.edu/JStorey1?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-15433595">+1</span><div class="hidden js-additional-users-15433595"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://sfu.academia.edu/StephenHart">Stephen D Hart</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-15433595'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-15433595').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_15433595 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="15433595"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 15433595, container: ".js-paper-rank-work_15433595", }); });</script></li><li class="js-percentile-work_15433595 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 15433595; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_15433595"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_15433595 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="15433595"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 15433595; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=15433595]").text(description); $(".js-view-count-work_15433595").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_15433595").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="15433595"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">7</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="189" rel="nofollow" href="https://www.academia.edu/Documents/in/Criminology">Criminology</a>, <script data-card-contents-for-ri="189" type="text/json">{"id":189,"name":"Criminology","url":"https://www.academia.edu/Documents/in/Criminology?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="12061" rel="nofollow" href="https://www.academia.edu/Documents/in/Risk_Management">Risk Management</a>, <script data-card-contents-for-ri="12061" type="text/json">{"id":12061,"name":"Risk Management","url":"https://www.academia.edu/Documents/in/Risk_Management?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="37778" rel="nofollow" href="https://www.academia.edu/Documents/in/Law_Enforcement">Law Enforcement</a><script data-card-contents-for-ri="37778" type="text/json">{"id":37778,"name":"Law Enforcement","url":"https://www.academia.edu/Documents/in/Law_Enforcement?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=15433595]'), work: {"id":15433595,"title":"How Do Police Respond to Stalking? An Examination of the Risk Management Strategies and Tactics Used in a Specialized Anti-Stalking Law Enforcement Unit","created_at":"2015-09-05T20:05:42.868-07:00","url":"https://www.academia.edu/15433595/How_Do_Police_Respond_to_Stalking_An_Examination_of_the_Risk_Management_Strategies_and_Tactics_Used_in_a_Specialized_Anti_Stalking_Law_Enforcement_Unit?f_ri=620049","dom_id":"work_15433595","summary":"How do police respond to and manage complaints of stalking? To answer this question, we conducted a 3-phase study. First, we reviewed the literature to identify risk management tactics used to combat stalking. Second, we asked a group of police officers to review those tactics for completeness and group them into categories reflecting more general risk management strategies. The result was 22 categories of strategies. Finally, we used qualitative methods to evaluate the files of 32 cases referred to the specialized anti-stalking unit of a metropolitan police department. We coded specific risk management tactics and strategies used by police. Results indicated that a median number of 19 specific tactics from 7 general strategies were used to manage risk. Also, the implementation of strategies and tactics reflected specific characteristics of the cases (e.g., perpetrator risk factors, victim vulnerability factors), suggesting that the risk management decisions made by police were indeed strategic in nature. Qualitative analyses indicated that some of the strategies and tactics were more effective than others. We discuss how these findings can be used to understand and use stalking risk management more generally, as well as improve research on the efficacy of risk assessment and management for stalking.","downloadable_attachments":[{"id":43203410,"asset_id":15433595,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":34690978,"first_name":"J.","last_name":"Storey","domain_name":"independent","page_name":"JStorey1","display_name":"J. Storey","profile_url":"https://independent.academia.edu/JStorey1?f_ri=620049","photo":"/images/s65_no_pic.png"},{"id":34574939,"first_name":"Stephen","last_name":"Hart","domain_name":"sfu","page_name":"StephenHart","display_name":"Stephen D Hart","profile_url":"https://sfu.academia.edu/StephenHart?f_ri=620049","photo":"https://0.academia-photos.com/34574939/17566627/17628863/s65_stephen.hart.jpg"}],"research_interests":[{"id":189,"name":"Criminology","url":"https://www.academia.edu/Documents/in/Criminology?f_ri=620049","nofollow":true},{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=620049","nofollow":true},{"id":12061,"name":"Risk Management","url":"https://www.academia.edu/Documents/in/Risk_Management?f_ri=620049","nofollow":true},{"id":37778,"name":"Law Enforcement","url":"https://www.academia.edu/Documents/in/Law_Enforcement?f_ri=620049","nofollow":true},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":675549,"name":"Qualitative Method","url":"https://www.academia.edu/Documents/in/Qualitative_Method?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_26487357" data-work_id="26487357" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/26487357/Hypertension_in_Premenopausal_Women_Is_There_Any_Difference">Hypertension in Premenopausal Women: Is There Any Difference?</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Hypertension is one of the most important cardiovascular (CV) risk factor, and that lowering blood pressure levels reduces the incidence of CV morbidity and mortality. The higher incidence of hypertension in postmenopausal than in... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_26487357" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Hypertension is one of the most important cardiovascular (CV) risk factor, and that lowering blood pressure levels reduces the incidence of CV morbidity and mortality. The higher incidence of hypertension in postmenopausal than in pre-menopausal women raises the attention on the pathophysiological mechanisms potentially involved in post-menopausal ones and outweigh those involved in pre-menopausal women. However, CV disease is one of the leading causes of death in reproductive-age women. Thus, improved awareness, early identification and prompt clinical management of hypertension should be key elements in order to prevent hypertension-related CV morbidity and mortality in pre-menopausal women. However, available data in this specific age group of women are relatively poor and inconsistent, so that the clinical management of young hypertensive women is still debated. The aim of this review is to assess whether there are clear evidences on differences between men and women in epidemiological data, pathophysiological mechanisms, diagnostic options and therapeutic interventions of hypertension and its prognosis, in order to establish the correct approach to this group of hypertensive patients.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/26487357" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="89983a653a7d2739dff6f16be447f5f0" rel="nofollow" data-download="{"attachment_id":46783516,"asset_id":26487357,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46783516/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="50448456" href="https://uniroma1.academia.edu/GiuliaPignatelli">Giulia Pignatelli</a><script data-card-contents-for-user="50448456" type="text/json">{"id":50448456,"first_name":"Giulia","last_name":"Pignatelli","domain_name":"uniroma1","page_name":"GiuliaPignatelli","display_name":"Giulia Pignatelli","profile_url":"https://uniroma1.academia.edu/GiuliaPignatelli?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_26487357 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="26487357"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 26487357, container: ".js-paper-rank-work_26487357", }); 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$(".js-view-count[data-work-id=26487357]").text(description); $(".js-view-count-work_26487357").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_26487357").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="26487357"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">7</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="71399" rel="nofollow" href="https://www.academia.edu/Documents/in/Hypertension">Hypertension</a>, <script data-card-contents-for-ri="71399" type="text/json">{"id":71399,"name":"Hypertension","url":"https://www.academia.edu/Documents/in/Hypertension?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="192721" rel="nofollow" href="https://www.academia.edu/Documents/in/Risk_factors">Risk factors</a>, <script data-card-contents-for-ri="192721" type="text/json">{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="289271" rel="nofollow" href="https://www.academia.edu/Documents/in/Aged">Aged</a>, <script data-card-contents-for-ri="289271" type="text/json">{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="489727" rel="nofollow" href="https://www.academia.edu/Documents/in/Prognosis">Prognosis</a><script data-card-contents-for-ri="489727" type="text/json">{"id":489727,"name":"Prognosis","url":"https://www.academia.edu/Documents/in/Prognosis?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=26487357]'), work: {"id":26487357,"title":"Hypertension in Premenopausal Women: Is There Any Difference?","created_at":"2016-06-25T08:44:49.891-07:00","url":"https://www.academia.edu/26487357/Hypertension_in_Premenopausal_Women_Is_There_Any_Difference?f_ri=620049","dom_id":"work_26487357","summary":"Hypertension is one of the most important cardiovascular (CV) risk factor, and that lowering blood pressure levels reduces the incidence of CV morbidity and mortality. The higher incidence of hypertension in postmenopausal than in pre-menopausal women raises the attention on the pathophysiological mechanisms potentially involved in post-menopausal ones and outweigh those involved in pre-menopausal women. However, CV disease is one of the leading causes of death in reproductive-age women. Thus, improved awareness, early identification and prompt clinical management of hypertension should be key elements in order to prevent hypertension-related CV morbidity and mortality in pre-menopausal women. However, available data in this specific age group of women are relatively poor and inconsistent, so that the clinical management of young hypertensive women is still debated. The aim of this review is to assess whether there are clear evidences on differences between men and women in epidemiological data, pathophysiological mechanisms, diagnostic options and therapeutic interventions of hypertension and its prognosis, in order to establish the correct approach to this group of hypertensive patients.","downloadable_attachments":[{"id":46783516,"asset_id":26487357,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":50448456,"first_name":"Giulia","last_name":"Pignatelli","domain_name":"uniroma1","page_name":"GiuliaPignatelli","display_name":"Giulia Pignatelli","profile_url":"https://uniroma1.academia.edu/GiuliaPignatelli?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":71399,"name":"Hypertension","url":"https://www.academia.edu/Documents/in/Hypertension?f_ri=620049","nofollow":true},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049","nofollow":true},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=620049","nofollow":true},{"id":489727,"name":"Prognosis","url":"https://www.academia.edu/Documents/in/Prognosis?f_ri=620049","nofollow":true},{"id":546419,"name":"Age Factors","url":"https://www.academia.edu/Documents/in/Age_Factors?f_ri=620049"},{"id":559242,"name":"Cardiovascular Diseases","url":"https://www.academia.edu/Documents/in/Cardiovascular_Diseases?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_24350641" data-work_id="24350641" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/24350641/Importance_of_characteristics_and_modalities_of_physical_activity_and_exercise_in_the_management_of_cardiovascular_health_in_individuals_with_cardiovascular_disease_Part_III_">Importance of characteristics and modalities of physical activity and exercise in the management of cardiovascular health in individuals with cardiovascular disease (Part III)</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The beneficial effect of exercise training and exercise-based cardiac rehabilitation on symptom-free exercise capacity,cardiovascular and skeletal muscle function, quality of life, general healthy lifestyle, and reduction of depressive... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_24350641" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The beneficial effect of exercise training and exercise-based cardiac rehabilitation on symptom-free exercise capacity,cardiovascular and skeletal muscle function, quality of life, general healthy lifestyle, and reduction of depressive symptoms and psychosocial stress is nowadays well recognized. However, it remains largely obscure, which characteristics of physical activity (PA) and exercise training--frequency, intensity, time (duration), type (mode), and volume (dose: intensity x duration) of exercise--are the most effective. The present paper, therefore, will deal with these exercise characteristics in the management of individuals with cardiovascular disease, i.e. coronary artery disease and chronic heart failure patients, but also in patients with congenital or valvular heart disease. Based on the current literature, and if sufficient evidence is available, recommendations from the European Association on Cardiovascular Prevention and Rehabilitation are formulated regarding fr...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/24350641" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="59a83bb3fcac457afe60c16f167657bf" rel="nofollow" data-download="{"attachment_id":44684342,"asset_id":24350641,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44684342/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="46949011" href="https://rub.academia.edu/FVanBuuren">F. Van Buuren</a><script data-card-contents-for-user="46949011" type="text/json">{"id":46949011,"first_name":"F. Van","last_name":"Buuren","domain_name":"rub","page_name":"FVanBuuren","display_name":"F. Van Buuren","profile_url":"https://rub.academia.edu/FVanBuuren?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_24350641 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="24350641"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 24350641, container: ".js-paper-rank-work_24350641", }); });</script></li><li class="js-percentile-work_24350641 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 24350641; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_24350641"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_24350641 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="24350641"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 24350641; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=24350641]").text(description); $(".js-view-count-work_24350641").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_24350641").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="24350641"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">14</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="3851" rel="nofollow" href="https://www.academia.edu/Documents/in/Obesity">Obesity</a>, <script data-card-contents-for-ri="3851" type="text/json">{"id":3851,"name":"Obesity","url":"https://www.academia.edu/Documents/in/Obesity?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="9112" rel="nofollow" href="https://www.academia.edu/Documents/in/Physical_Activity">Physical Activity</a>, <script data-card-contents-for-ri="9112" type="text/json">{"id":9112,"name":"Physical Activity","url":"https://www.academia.edu/Documents/in/Physical_Activity?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="12426" rel="nofollow" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a>, <script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="16288" rel="nofollow" href="https://www.academia.edu/Documents/in/Public_Health">Public Health</a><script data-card-contents-for-ri="16288" type="text/json">{"id":16288,"name":"Public Health","url":"https://www.academia.edu/Documents/in/Public_Health?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=24350641]'), work: {"id":24350641,"title":"Importance of characteristics and modalities of physical activity and exercise in the management of cardiovascular health in individuals with cardiovascular disease (Part III)","created_at":"2016-04-12T23:21:30.662-07:00","url":"https://www.academia.edu/24350641/Importance_of_characteristics_and_modalities_of_physical_activity_and_exercise_in_the_management_of_cardiovascular_health_in_individuals_with_cardiovascular_disease_Part_III_?f_ri=620049","dom_id":"work_24350641","summary":"The beneficial effect of exercise training and exercise-based cardiac rehabilitation on symptom-free exercise capacity,cardiovascular and skeletal muscle function, quality of life, general healthy lifestyle, and reduction of depressive symptoms and psychosocial stress is nowadays well recognized. However, it remains largely obscure, which characteristics of physical activity (PA) and exercise training--frequency, intensity, time (duration), type (mode), and volume (dose: intensity x duration) of exercise--are the most effective. The present paper, therefore, will deal with these exercise characteristics in the management of individuals with cardiovascular disease, i.e. coronary artery disease and chronic heart failure patients, but also in patients with congenital or valvular heart disease. Based on the current literature, and if sufficient evidence is available, recommendations from the European Association on Cardiovascular Prevention and Rehabilitation are formulated regarding fr...","downloadable_attachments":[{"id":44684342,"asset_id":24350641,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":46949011,"first_name":"F. Van","last_name":"Buuren","domain_name":"rub","page_name":"FVanBuuren","display_name":"F. Van Buuren","profile_url":"https://rub.academia.edu/FVanBuuren?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":3851,"name":"Obesity","url":"https://www.academia.edu/Documents/in/Obesity?f_ri=620049","nofollow":true},{"id":9112,"name":"Physical Activity","url":"https://www.academia.edu/Documents/in/Physical_Activity?f_ri=620049","nofollow":true},{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=620049","nofollow":true},{"id":16288,"name":"Public Health","url":"https://www.academia.edu/Documents/in/Public_Health?f_ri=620049","nofollow":true},{"id":24735,"name":"Cardiovascular disease","url":"https://www.academia.edu/Documents/in/Cardiovascular_disease?f_ri=620049"},{"id":25443,"name":"Exercise therapy","url":"https://www.academia.edu/Documents/in/Exercise_therapy?f_ri=620049"},{"id":44529,"name":"Activities of Daily Living","url":"https://www.academia.edu/Documents/in/Activities_of_Daily_Living?f_ri=620049"},{"id":135185,"name":"Exercise","url":"https://www.academia.edu/Documents/in/Exercise?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=620049"},{"id":559242,"name":"Cardiovascular Diseases","url":"https://www.academia.edu/Documents/in/Cardiovascular_Diseases?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":1210716,"name":"Exercise Tolerance","url":"https://www.academia.edu/Documents/in/Exercise_Tolerance?f_ri=620049"},{"id":2246318,"name":"Motor activity","url":"https://www.academia.edu/Documents/in/Motor_activity?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_8111331" data-work_id="8111331" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/8111331/The_effect_of_gestational_age_on_developmental_outcomes_a_longitudinal_study_in_the_first_2_years_of_life_Gestational_age_and_developmental_outcomes">The effect of gestational age on developmental outcomes: a longitudinal study in the first 2 years of life: Gestational age and developmental outcomes</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Background Extremely low and very low gestational age (ELGA and VLGA) constitutes a risk factor for development even in absence of cerebral damage, as an immature central nervous system is exposed to invasive and inadequate stimulation.... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_8111331" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Background Extremely low and very low gestational age (ELGA and VLGA) constitutes a risk factor for development even in absence of cerebral damage, as an immature central nervous system is exposed to invasive and inadequate stimulation. We tested the hypothesis that GA impacts developmental outcomes and trajectories of preterms without major cerebral damage in the first 2 years of life, expecting poorer developmental outcomes and higher rate of impairment with the decreasing of GA. We also evaluated whether GA, together with developmental outcomes in the first year of life, was related to developmental outcomes at 24 months.Methods Eighty-eight infants, divided into three GA groups (ELGA: ≤28 weeks; VLGA: 29–32 weeks; full term: >37 weeks) were assessed longitudinally at 6, 12, 18 and 24 months using the Griffiths Mental Development Scales.Results Use of a repeated measure multivariate analysis of variance resulted in several significant findings. GA was associated with the developmental quotient (DQ) scores (P= 0.006); and locomotor (P < 0.001), eye and hand co-ordination (P= 0.016) and performance (P= 0.040) sub-scale quotient (SQ) scores; age of evaluation was also associated with DQ scores (P= 0.002), and locomotor (P < 0.001) and performance (P < 0.001) SQ scores. In particular, ELGAs exhibited lower DQ and SQ scores compared with the VLGA and full-term groups; some ELGAs showed mild, moderate or severe cognitive impairments, while few VLGAs mild impairments. Linear regression analysis showed that GA (P= 0.034) and 12-month developmental outcome (P < 0.001) were related to 24-month developmental outcome.Conclusions Different developmental trajectories emerged in relation to GA, with poorer developmental outcomes and higher rates of impairment in ELGAs and few mild impairments in VLGAs. The relevance of taking into account both GA and repeated assessments in the first 2 years of life was shown.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/8111331" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="8102cd94b538fc2f97902a1a1854b4cf" rel="nofollow" data-download="{"attachment_id":48211402,"asset_id":8111331,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48211402/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="15743073" href="https://unibo.academia.edu/AlessandraSansavini">Alessandra Sansavini</a><script data-card-contents-for-user="15743073" type="text/json">{"id":15743073,"first_name":"Alessandra","last_name":"Sansavini","domain_name":"unibo","page_name":"AlessandraSansavini","display_name":"Alessandra Sansavini","profile_url":"https://unibo.academia.edu/AlessandraSansavini?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_8111331 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="8111331"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 8111331, container: ".js-paper-rank-work_8111331", }); 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$(".js-view-count[data-work-id=8111331]").text(description); $(".js-view-count-work_8111331").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_8111331").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="8111331"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">15</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="922" rel="nofollow" href="https://www.academia.edu/Documents/in/Education">Education</a>, <script data-card-contents-for-ri="922" type="text/json">{"id":922,"name":"Education","url":"https://www.academia.edu/Documents/in/Education?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4583" rel="nofollow" href="https://www.academia.edu/Documents/in/Child_Development">Child Development</a>, <script data-card-contents-for-ri="4583" type="text/json">{"id":4583,"name":"Child Development","url":"https://www.academia.edu/Documents/in/Child_Development?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="45213" rel="nofollow" href="https://www.academia.edu/Documents/in/Italy">Italy</a>, <script data-card-contents-for-ri="45213" type="text/json">{"id":45213,"name":"Italy","url":"https://www.academia.edu/Documents/in/Italy?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="134346" rel="nofollow" href="https://www.academia.edu/Documents/in/Infant">Infant</a><script data-card-contents-for-ri="134346" type="text/json">{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=8111331]'), work: {"id":8111331,"title":"The effect of gestational age on developmental outcomes: a longitudinal study in the first 2 years of life: Gestational age and developmental outcomes","created_at":"2014-08-27T23:33:40.310-07:00","url":"https://www.academia.edu/8111331/The_effect_of_gestational_age_on_developmental_outcomes_a_longitudinal_study_in_the_first_2_years_of_life_Gestational_age_and_developmental_outcomes?f_ri=620049","dom_id":"work_8111331","summary":"Background Extremely low and very low gestational age (ELGA and VLGA) constitutes a risk factor for development even in absence of cerebral damage, as an immature central nervous system is exposed to invasive and inadequate stimulation. We tested the hypothesis that GA impacts developmental outcomes and trajectories of preterms without major cerebral damage in the first 2 years of life, expecting poorer developmental outcomes and higher rate of impairment with the decreasing of GA. We also evaluated whether GA, together with developmental outcomes in the first year of life, was related to developmental outcomes at 24 months.Methods Eighty-eight infants, divided into three GA groups (ELGA: ≤28 weeks; VLGA: 29–32 weeks; full term: \u003e37 weeks) were assessed longitudinally at 6, 12, 18 and 24 months using the Griffiths Mental Development Scales.Results Use of a repeated measure multivariate analysis of variance resulted in several significant findings. GA was associated with the developmental quotient (DQ) scores (P= 0.006); and locomotor (P \u003c 0.001), eye and hand co-ordination (P= 0.016) and performance (P= 0.040) sub-scale quotient (SQ) scores; age of evaluation was also associated with DQ scores (P= 0.002), and locomotor (P \u003c 0.001) and performance (P \u003c 0.001) SQ scores. In particular, ELGAs exhibited lower DQ and SQ scores compared with the VLGA and full-term groups; some ELGAs showed mild, moderate or severe cognitive impairments, while few VLGAs mild impairments. Linear regression analysis showed that GA (P= 0.034) and 12-month developmental outcome (P \u003c 0.001) were related to 24-month developmental outcome.Conclusions Different developmental trajectories emerged in relation to GA, with poorer developmental outcomes and higher rates of impairment in ELGAs and few mild impairments in VLGAs. The relevance of taking into account both GA and repeated assessments in the first 2 years of life was shown.","downloadable_attachments":[{"id":48211402,"asset_id":8111331,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":15743073,"first_name":"Alessandra","last_name":"Sansavini","domain_name":"unibo","page_name":"AlessandraSansavini","display_name":"Alessandra Sansavini","profile_url":"https://unibo.academia.edu/AlessandraSansavini?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":922,"name":"Education","url":"https://www.academia.edu/Documents/in/Education?f_ri=620049","nofollow":true},{"id":4583,"name":"Child Development","url":"https://www.academia.edu/Documents/in/Child_Development?f_ri=620049","nofollow":true},{"id":45213,"name":"Italy","url":"https://www.academia.edu/Documents/in/Italy?f_ri=620049","nofollow":true},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=620049","nofollow":true},{"id":137145,"name":"Developmental disabilities","url":"https://www.academia.edu/Documents/in/Developmental_disabilities?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":330953,"name":"Longitudinal Studies","url":"https://www.academia.edu/Documents/in/Longitudinal_Studies?f_ri=620049"},{"id":413194,"name":"Analysis of Variance","url":"https://www.academia.edu/Documents/in/Analysis_of_Variance?f_ri=620049"},{"id":414843,"name":"Longitudinal Study","url":"https://www.academia.edu/Documents/in/Longitudinal_Study?f_ri=620049"},{"id":428130,"name":"Cognitive Ability","url":"https://www.academia.edu/Documents/in/Cognitive_Ability?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":797418,"name":"Gestational Age","url":"https://www.academia.edu/Documents/in/Gestational_Age?f_ri=620049"},{"id":1627527,"name":"Cognition disorders","url":"https://www.academia.edu/Documents/in/Cognition_disorders?f_ri=620049"},{"id":2463800,"name":"Severity of Illness Index","url":"https://www.academia.edu/Documents/in/Severity_of_Illness_Index?f_ri=620049"},{"id":2489700,"name":"Child preschool","url":"https://www.academia.edu/Documents/in/Child_preschool?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_27449224 coauthored" data-work_id="27449224" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/27449224/Leaflet_area_as_a_determinant_of_tricuspid_regurgitation_severity_in_patients_with_pulmonary_hypertension">Leaflet area as a determinant of tricuspid regurgitation severity in patients with pulmonary hypertension</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Tricuspid regurgitation (TR) is a risk factor for mortality in pulmonary hypertension (PH). TR severity varies among patients with comparable degrees of PH and right ventricular remodeling. The contribution of leaflet adaptation to the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_27449224" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Tricuspid regurgitation (TR) is a risk factor for mortality in pulmonary hypertension (PH). TR severity varies among patients with comparable degrees of PH and right ventricular remodeling. The contribution of leaflet adaptation to the pathophysiology of TR has yet to be examined. We hypothesized that tricuspid leaflet area (TLA) is increased in PH, and that the adequacy of this increase relative to right ventricular remodeling determines TR severity. A prospective cohort of 255 patients with PH from pre and postcapillary pathogeneses was assembled from 2 centers. Patients underwent a 3-dimensional echocardiogram focused on the tricuspid apparatus. TLA was measured with the Omni 4D software package. Compared with normal controls, patients with PH had a 2-fold increase in right ventricular volumes, 62% increase in annular area, and 49% increase in TLA. Those with severe TR demonstrated inadequate increase in TLA relative to the closure area, such that the ratio of TLA:closure area &l...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/27449224" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="e2542e6878689b91545fdc482eb01a3d" rel="nofollow" data-download="{"attachment_id":47707492,"asset_id":27449224,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/47707492/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="51586568" href="https://independent.academia.edu/LanqiHua">Lanqi Hua</a><script data-card-contents-for-user="51586568" type="text/json">{"id":51586568,"first_name":"Lanqi","last_name":"Hua","domain_name":"independent","page_name":"LanqiHua","display_name":"Lanqi Hua","profile_url":"https://independent.academia.edu/LanqiHua?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-27449224">+1</span><div class="hidden js-additional-users-27449224"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/MarkHandschumacher">Mark Handschumacher</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-27449224'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-27449224').html(); 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container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_27449224 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="27449224"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 27449224; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=27449224]").text(description); $(".js-view-count-work_27449224").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_27449224").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="27449224"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="31958" rel="nofollow" href="https://www.academia.edu/Documents/in/Pulmonary_Hypertension">Pulmonary Hypertension</a>, <script data-card-contents-for-ri="31958" type="text/json">{"id":31958,"name":"Pulmonary Hypertension","url":"https://www.academia.edu/Documents/in/Pulmonary_Hypertension?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="53293" rel="nofollow" href="https://www.academia.edu/Documents/in/Software">Software</a>, <script data-card-contents-for-ri="53293" type="text/json">{"id":53293,"name":"Software","url":"https://www.academia.edu/Documents/in/Software?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a>, <script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="192721" rel="nofollow" href="https://www.academia.edu/Documents/in/Risk_factors">Risk factors</a><script data-card-contents-for-ri="192721" type="text/json">{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=27449224]'), work: {"id":27449224,"title":"Leaflet area as a determinant of tricuspid regurgitation severity in patients with pulmonary hypertension","created_at":"2016-08-01T15:59:53.111-07:00","url":"https://www.academia.edu/27449224/Leaflet_area_as_a_determinant_of_tricuspid_regurgitation_severity_in_patients_with_pulmonary_hypertension?f_ri=620049","dom_id":"work_27449224","summary":"Tricuspid regurgitation (TR) is a risk factor for mortality in pulmonary hypertension (PH). TR severity varies among patients with comparable degrees of PH and right ventricular remodeling. The contribution of leaflet adaptation to the pathophysiology of TR has yet to be examined. We hypothesized that tricuspid leaflet area (TLA) is increased in PH, and that the adequacy of this increase relative to right ventricular remodeling determines TR severity. A prospective cohort of 255 patients with PH from pre and postcapillary pathogeneses was assembled from 2 centers. Patients underwent a 3-dimensional echocardiogram focused on the tricuspid apparatus. TLA was measured with the Omni 4D software package. Compared with normal controls, patients with PH had a 2-fold increase in right ventricular volumes, 62% increase in annular area, and 49% increase in TLA. Those with severe TR demonstrated inadequate increase in TLA relative to the closure area, such that the ratio of TLA:closure area \u0026l...","downloadable_attachments":[{"id":47707492,"asset_id":27449224,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":51586568,"first_name":"Lanqi","last_name":"Hua","domain_name":"independent","page_name":"LanqiHua","display_name":"Lanqi Hua","profile_url":"https://independent.academia.edu/LanqiHua?f_ri=620049","photo":"/images/s65_no_pic.png"},{"id":51666062,"first_name":"Mark","last_name":"Handschumacher","domain_name":"independent","page_name":"MarkHandschumacher","display_name":"Mark Handschumacher","profile_url":"https://independent.academia.edu/MarkHandschumacher?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":31958,"name":"Pulmonary Hypertension","url":"https://www.academia.edu/Documents/in/Pulmonary_Hypertension?f_ri=620049","nofollow":true},{"id":53293,"name":"Software","url":"https://www.academia.edu/Documents/in/Software?f_ri=620049","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=620049","nofollow":true},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":803294,"name":"Ventricular Remodeling","url":"https://www.academia.edu/Documents/in/Ventricular_Remodeling?f_ri=620049"},{"id":1819399,"name":"Case Control Studies","url":"https://www.academia.edu/Documents/in/Case_Control_Studies?f_ri=620049"},{"id":2463800,"name":"Severity of Illness Index","url":"https://www.academia.edu/Documents/in/Severity_of_Illness_Index?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_68128083" data-work_id="68128083" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/68128083/Pilot_Study_Survey_Tools_for_Assessing_Parenting_Styles_and_Family_Contributors_to_the_Development_of_Obesity_in_Arab_Children_Ages_6_12_Years_Old">Pilot Study: Survey Tools for Assessing Parenting Styles and Family Contributors to the Development of Obesity in Arab Children Ages 6 – 12 Years Old</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Family environmental factors and parenting styles can be major determinants of obesity risk in children. 1-4 According to the Centers for Disease Control and Prevention, in 2012, 18% of children (aged 6-11 years) were obese, and 21% of... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_68128083" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Family environmental factors and parenting styles can be major determinants of obesity risk in children. 1-4 According to the Centers for Disease Control and Prevention, in 2012, 18% of children (aged 6-11 years) were obese, and 21% of adolescents (aged 12-19 years) were obese in the United States. 5 In Arabic-speaking countries, the prevalence of obesity in children and adolescents ranges from 5% to 14% in males and from 3% to 18% in females. 6 However, there is a lack of accurate and comprehensive data on the extent of the problem of obesity among Arab children. 7 To prevent obesity in Arab children, there is a need for research on parenting styles and family factors contributing to obesity so that nutrition education programs can be developed to address these factors. The validat</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/68128083" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="66f655382b47624fed5a2fd0c5f06176" rel="nofollow" data-download="{"attachment_id":78714967,"asset_id":68128083,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/78714967/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="212355661" href="https://independent.academia.edu/SuzanTami">Suzan Tami</a><script data-card-contents-for-user="212355661" type="text/json">{"id":212355661,"first_name":"Suzan","last_name":"Tami","domain_name":"independent","page_name":"SuzanTami","display_name":"Suzan Tami","profile_url":"https://independent.academia.edu/SuzanTami?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_68128083 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="68128083"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 68128083, container: ".js-paper-rank-work_68128083", }); 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$(".js-view-count[data-work-id=68128083]").text(description); $(".js-view-count-work_68128083").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_68128083").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="68128083"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">14</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="3851" rel="nofollow" href="https://www.academia.edu/Documents/in/Obesity">Obesity</a>, <script data-card-contents-for-ri="3851" type="text/json">{"id":3851,"name":"Obesity","url":"https://www.academia.edu/Documents/in/Obesity?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4545" rel="nofollow" href="https://www.academia.edu/Documents/in/Parenting">Parenting</a>, <script data-card-contents-for-ri="4545" type="text/json">{"id":4545,"name":"Parenting","url":"https://www.academia.edu/Documents/in/Parenting?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="64933" rel="nofollow" href="https://www.academia.edu/Documents/in/Child">Child</a>, <script data-card-contents-for-ri="64933" type="text/json">{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="98134" rel="nofollow" href="https://www.academia.edu/Documents/in/United_States">United States</a><script data-card-contents-for-ri="98134" type="text/json">{"id":98134,"name":"United States","url":"https://www.academia.edu/Documents/in/United_States?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=68128083]'), work: {"id":68128083,"title":"Pilot Study: Survey Tools for Assessing Parenting Styles and Family Contributors to the Development of Obesity in Arab Children Ages 6 – 12 Years Old","created_at":"2022-01-14T08:02:04.467-08:00","url":"https://www.academia.edu/68128083/Pilot_Study_Survey_Tools_for_Assessing_Parenting_Styles_and_Family_Contributors_to_the_Development_of_Obesity_in_Arab_Children_Ages_6_12_Years_Old?f_ri=620049","dom_id":"work_68128083","summary":"Family environmental factors and parenting styles can be major determinants of obesity risk in children. 1-4 According to the Centers for Disease Control and Prevention, in 2012, 18% of children (aged 6-11 years) were obese, and 21% of adolescents (aged 12-19 years) were obese in the United States. 5 In Arabic-speaking countries, the prevalence of obesity in children and adolescents ranges from 5% to 14% in males and from 3% to 18% in females. 6 However, there is a lack of accurate and comprehensive data on the extent of the problem of obesity among Arab children. 7 To prevent obesity in Arab children, there is a need for research on parenting styles and family factors contributing to obesity so that nutrition education programs can be developed to address these factors. The validat","downloadable_attachments":[{"id":78714967,"asset_id":68128083,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":212355661,"first_name":"Suzan","last_name":"Tami","domain_name":"independent","page_name":"SuzanTami","display_name":"Suzan Tami","profile_url":"https://independent.academia.edu/SuzanTami?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":3851,"name":"Obesity","url":"https://www.academia.edu/Documents/in/Obesity?f_ri=620049","nofollow":true},{"id":4545,"name":"Parenting","url":"https://www.academia.edu/Documents/in/Parenting?f_ri=620049","nofollow":true},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=620049","nofollow":true},{"id":98134,"name":"United States","url":"https://www.academia.edu/Documents/in/United_States?f_ri=620049","nofollow":true},{"id":162282,"name":"Mothers","url":"https://www.academia.edu/Documents/in/Mothers?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":202574,"name":"Feeding Behavior","url":"https://www.academia.edu/Documents/in/Feeding_Behavior?f_ri=620049"},{"id":362284,"name":"Arabs","url":"https://www.academia.edu/Documents/in/Arabs?f_ri=620049"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=620049"},{"id":549280,"name":"Reproducibility of Results","url":"https://www.academia.edu/Documents/in/Reproducibility_of_Results?f_ri=620049"},{"id":557260,"name":"Health surveys","url":"https://www.academia.edu/Documents/in/Health_surveys?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":945595,"name":"Pilot Projects","url":"https://www.academia.edu/Documents/in/Pilot_Projects?f_ri=620049"},{"id":2345130,"name":"Socioeconomic Factors","url":"https://www.academia.edu/Documents/in/Socioeconomic_Factors?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_21489234" data-work_id="21489234" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/21489234/Bipolar_cord_coagulation_for_selective_feticide_in_complicated_monochorionic_twin_pregnancies_118_consecutive_cases_at_a_single_center">Bipolar cord coagulation for selective feticide in complicated monochorionic twin pregnancies: 118 consecutive cases at a single center</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">Objective To review the experience of performing selective feticide with bipolar cord coagulation (BCC) in complicated monochorionic (MC) twin pregnancies at a single center.</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/21489234" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a8b6529d3264d3ec2d786391da922a23" rel="nofollow" data-download="{"attachment_id":41918908,"asset_id":21489234,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" 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class="js-paper-rank-work_21489234 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="21489234"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 21489234, container: ".js-paper-rank-work_21489234", }); });</script></li><li class="js-percentile-work_21489234 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 21489234; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_21489234"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_21489234 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="21489234"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 21489234; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=21489234]").text(description); $(".js-view-count-work_21489234").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_21489234").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="21489234"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">8</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="62550" rel="nofollow" href="https://www.academia.edu/Documents/in/Pregnancy">Pregnancy</a>, <script data-card-contents-for-ri="62550" type="text/json">{"id":62550,"name":"Pregnancy","url":"https://www.academia.edu/Documents/in/Pregnancy?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="192721" rel="nofollow" href="https://www.academia.edu/Documents/in/Risk_factors">Risk factors</a>, <script data-card-contents-for-ri="192721" type="text/json">{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="253560" rel="nofollow" href="https://www.academia.edu/Documents/in/Newborn_Infant">Newborn Infant</a>, <script data-card-contents-for-ri="253560" type="text/json">{"id":253560,"name":"Newborn Infant","url":"https://www.academia.edu/Documents/in/Newborn_Infant?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="469105" rel="nofollow" href="https://www.academia.edu/Documents/in/Retrospective_Studies">Retrospective Studies</a><script data-card-contents-for-ri="469105" type="text/json">{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=21489234]'), work: {"id":21489234,"title":"Bipolar cord coagulation for selective feticide in complicated monochorionic twin pregnancies: 118 consecutive cases at a single center","created_at":"2016-02-02T21:49:53.591-08:00","url":"https://www.academia.edu/21489234/Bipolar_cord_coagulation_for_selective_feticide_in_complicated_monochorionic_twin_pregnancies_118_consecutive_cases_at_a_single_center?f_ri=620049","dom_id":"work_21489234","summary":"Objective To review the experience of performing selective feticide with bipolar cord coagulation (BCC) in complicated monochorionic (MC) twin pregnancies at a single center.","downloadable_attachments":[{"id":41918908,"asset_id":21489234,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":42576669,"first_name":"Stefano","last_name":"Faiola","domain_name":"independent","page_name":"StefanoFaiola","display_name":"Stefano Faiola","profile_url":"https://independent.academia.edu/StefanoFaiola?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":62550,"name":"Pregnancy","url":"https://www.academia.edu/Documents/in/Pregnancy?f_ri=620049","nofollow":true},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049","nofollow":true},{"id":253560,"name":"Newborn Infant","url":"https://www.academia.edu/Documents/in/Newborn_Infant?f_ri=620049","nofollow":true},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=620049","nofollow":true},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":1014746,"name":"Amnion","url":"https://www.academia.edu/Documents/in/Amnion?f_ri=620049"},{"id":1112003,"name":"Umbilical Cord","url":"https://www.academia.edu/Documents/in/Umbilical_Cord?f_ri=620049"},{"id":1179060,"name":"Fetal death","url":"https://www.academia.edu/Documents/in/Fetal_death?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_8542120" data-work_id="8542120" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/8542120/Management_of_cardiovascular_risk_in_the_peri_menopausal_woman_a_consensus_statement_of_European_cardiologists_and_gynaecologists">Management of cardiovascular risk in the peri-menopausal woman: a consensus statement of European cardiologists and gynaecologists</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Cardiovascular risk is poorly managed in women, especially during the menopausal transition when susceptibility to cardiovascular events increases. Clear gender differences exist in the epidemiology, symptoms, diagnosis, progression,... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_8542120" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Cardiovascular risk is poorly managed in women, especially during the menopausal transition when susceptibility to cardiovascular events increases. Clear gender differences exist in the epidemiology, symptoms, diagnosis, progression, prognosis, and management of cardiovascular risk. Key risk factors that need to be controlled in the peri-menopausal woman are hypertension, dyslipidaemia, obesity, and other components of the metabolic syndrome, with the avoidance and careful control of diabetes. Hypertension is a particularly powerful risk factor and lowering of blood pressure is pivotal. Hormone replacement therapy is acknowledged as the gold standard for the alleviation of the distressing vasomotor symptoms of the menopause, but the findings of the Women's Health Initiative (WHI) study generated concern for the detrimental effect on cardiovascular events. Thus, hormone replacement therapy cannot be recommended for the prevention of cardiovascular disease. Whether the findings of WHI in older post-menopausal women can be applied to younger peri-menopausal women is unknown. It is increasingly recognized that hormone therapy is inappropriate for older post-menopausal women no longer displaying menopausal symptoms. Both gynaecologists and cardiovascular physicians have an important role to play in identifying peri-menopausal women at risk of cardiovascular morbidity and mortality and should work as a team to identify and manage risk factors such as hypertension.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/8542120" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="6b984385ec89aaf28e4c99ff555b9839" rel="nofollow" data-download="{"attachment_id":48060867,"asset_id":8542120,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48060867/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="17556822" href="https://untag-sby.academia.edu/tomyraymond">tomy raymond</a><script data-card-contents-for-user="17556822" type="text/json">{"id":17556822,"first_name":"tomy","last_name":"raymond","domain_name":"untag-sby","page_name":"tomyraymond","display_name":"tomy raymond","profile_url":"https://untag-sby.academia.edu/tomyraymond?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_8542120 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="8542120"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 8542120, container: ".js-paper-rank-work_8542120", }); 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$(".js-view-count[data-work-id=8542120]").text(description); $(".js-view-count-work_8542120").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_8542120").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="8542120"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">34</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="606" rel="nofollow" href="https://www.academia.edu/Documents/in/Cardiology">Cardiology</a>, <script data-card-contents-for-ri="606" type="text/json">{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="618" rel="nofollow" href="https://www.academia.edu/Documents/in/Gynaecology">Gynaecology</a>, <script data-card-contents-for-ri="618" type="text/json">{"id":618,"name":"Gynaecology","url":"https://www.academia.edu/Documents/in/Gynaecology?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="3851" rel="nofollow" href="https://www.academia.edu/Documents/in/Obesity">Obesity</a>, <script data-card-contents-for-ri="3851" type="text/json">{"id":3851,"name":"Obesity","url":"https://www.academia.edu/Documents/in/Obesity?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="8015" rel="nofollow" href="https://www.academia.edu/Documents/in/Atherosclerosis">Atherosclerosis</a><script data-card-contents-for-ri="8015" type="text/json">{"id":8015,"name":"Atherosclerosis","url":"https://www.academia.edu/Documents/in/Atherosclerosis?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=8542120]'), work: {"id":8542120,"title":"Management of cardiovascular risk in the peri-menopausal woman: a consensus statement of European cardiologists and gynaecologists","created_at":"2014-09-28T20:20:14.160-07:00","url":"https://www.academia.edu/8542120/Management_of_cardiovascular_risk_in_the_peri_menopausal_woman_a_consensus_statement_of_European_cardiologists_and_gynaecologists?f_ri=620049","dom_id":"work_8542120","summary":"Cardiovascular risk is poorly managed in women, especially during the menopausal transition when susceptibility to cardiovascular events increases. Clear gender differences exist in the epidemiology, symptoms, diagnosis, progression, prognosis, and management of cardiovascular risk. Key risk factors that need to be controlled in the peri-menopausal woman are hypertension, dyslipidaemia, obesity, and other components of the metabolic syndrome, with the avoidance and careful control of diabetes. Hypertension is a particularly powerful risk factor and lowering of blood pressure is pivotal. Hormone replacement therapy is acknowledged as the gold standard for the alleviation of the distressing vasomotor symptoms of the menopause, but the findings of the Women's Health Initiative (WHI) study generated concern for the detrimental effect on cardiovascular events. Thus, hormone replacement therapy cannot be recommended for the prevention of cardiovascular disease. Whether the findings of WHI in older post-menopausal women can be applied to younger peri-menopausal women is unknown. It is increasingly recognized that hormone therapy is inappropriate for older post-menopausal women no longer displaying menopausal symptoms. Both gynaecologists and cardiovascular physicians have an important role to play in identifying peri-menopausal women at risk of cardiovascular morbidity and mortality and should work as a team to identify and manage risk factors such as hypertension.","downloadable_attachments":[{"id":48060867,"asset_id":8542120,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":17556822,"first_name":"tomy","last_name":"raymond","domain_name":"untag-sby","page_name":"tomyraymond","display_name":"tomy raymond","profile_url":"https://untag-sby.academia.edu/tomyraymond?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=620049","nofollow":true},{"id":618,"name":"Gynaecology","url":"https://www.academia.edu/Documents/in/Gynaecology?f_ri=620049","nofollow":true},{"id":3851,"name":"Obesity","url":"https://www.academia.edu/Documents/in/Obesity?f_ri=620049","nofollow":true},{"id":8015,"name":"Atherosclerosis","url":"https://www.academia.edu/Documents/in/Atherosclerosis?f_ri=620049","nofollow":true},{"id":12061,"name":"Risk Management","url":"https://www.academia.edu/Documents/in/Risk_Management?f_ri=620049"},{"id":16288,"name":"Public Health","url":"https://www.academia.edu/Documents/in/Public_Health?f_ri=620049"},{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=620049"},{"id":24735,"name":"Cardiovascular disease","url":"https://www.academia.edu/Documents/in/Cardiovascular_disease?f_ri=620049"},{"id":27240,"name":"Prevention","url":"https://www.academia.edu/Documents/in/Prevention?f_ri=620049"},{"id":29154,"name":"Cardiovascular Risk","url":"https://www.academia.edu/Documents/in/Cardiovascular_Risk?f_ri=620049"},{"id":37818,"name":"Metabolic syndrome","url":"https://www.academia.edu/Documents/in/Metabolic_syndrome?f_ri=620049"},{"id":71399,"name":"Hypertension","url":"https://www.academia.edu/Documents/in/Hypertension?f_ri=620049"},{"id":71517,"name":"Metabolic diseases","url":"https://www.academia.edu/Documents/in/Metabolic_diseases?f_ri=620049"},{"id":75318,"name":"Smoking","url":"https://www.academia.edu/Documents/in/Smoking?f_ri=620049"},{"id":75826,"name":"Europe","url":"https://www.academia.edu/Documents/in/Europe?f_ri=620049"},{"id":83306,"name":"Consensus","url":"https://www.academia.edu/Documents/in/Consensus?f_ri=620049"},{"id":88321,"name":"Blood Pressure","url":"https://www.academia.edu/Documents/in/Blood_Pressure?f_ri=620049"},{"id":104853,"name":"Hormones","url":"https://www.academia.edu/Documents/in/Hormones?f_ri=620049"},{"id":113812,"name":"Gender Difference","url":"https://www.academia.edu/Documents/in/Gender_Difference?f_ri=620049"},{"id":135185,"name":"Exercise","url":"https://www.academia.edu/Documents/in/Exercise?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=620049"},{"id":313752,"name":"Gold Standard","url":"https://www.academia.edu/Documents/in/Gold_Standard?f_ri=620049"},{"id":313857,"name":"Risk Factor","url":"https://www.academia.edu/Documents/in/Risk_Factor?f_ri=620049"},{"id":339107,"name":"Gynecology","url":"https://www.academia.edu/Documents/in/Gynecology?f_ri=620049"},{"id":420633,"name":"Diabetes complications","url":"https://www.academia.edu/Documents/in/Diabetes_complications?f_ri=620049"},{"id":445233,"name":"Hormone","url":"https://www.academia.edu/Documents/in/Hormone?f_ri=620049"},{"id":559242,"name":"Cardiovascular Diseases","url":"https://www.academia.edu/Documents/in/Cardiovascular_Diseases?f_ri=620049"},{"id":595678,"name":"Hormone Therapy","url":"https://www.academia.edu/Documents/in/Hormone_Therapy?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":622589,"name":"Risk Assessment","url":"https://www.academia.edu/Documents/in/Risk_Assessment-2?f_ri=620049"},{"id":1292329,"name":"Primary Prevention","url":"https://www.academia.edu/Documents/in/Primary_Prevention?f_ri=620049"},{"id":1495801,"name":"Perimenopause","url":"https://www.academia.edu/Documents/in/Perimenopause?f_ri=620049"},{"id":1621167,"name":"Hormone Replacement Therapy","url":"https://www.academia.edu/Documents/in/Hormone_Replacement_Therapy?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_66906305" data-work_id="66906305" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" rel="nofollow" href="https://www.academia.edu/66906305/Uric_acid_and_cardiovascular_risk">Uric acid and cardiovascular risk</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">n engl j med 360;5 nejm.org january 29, 2009 538 Zaman K, Roy E, Arifeen SE, et al. Effectiveness of maternal 1. influenza immunization in mothers and infants. N Engl J Med 2008;359:1555-64. Ali HM, Scott R, Toms GL. The effect of foster... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_66906305" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">n engl j med 360;5 nejm.org january 29, 2009 538 Zaman K, Roy E, Arifeen SE, et al. Effectiveness of maternal 1. influenza immunization in mothers and infants. N Engl J Med 2008;359:1555-64. Ali HM, Scott R, Toms GL. The effect of foster feeding and 2. bottle feeding expressed breast-milk on the susceptibility of guinea-pig infants to influenza virus. Br J Exp Pathol 1989;70: 183-91. Chantry CJ, Howard CR, Auinger P. Full breastfeeding dura3. tion and associated decrease in respiratory tract infection in US children. Pediatrics 2006;117:425-32.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/66906305" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="109209391" href="https://independent.academia.edu/Crist%C3%B3balBueno">Cristóbal Bueno</a><script data-card-contents-for-user="109209391" type="text/json">{"id":109209391,"first_name":"Cristóbal","last_name":"Bueno","domain_name":"independent","page_name":"CristóbalBueno","display_name":"Cristóbal Bueno","profile_url":"https://independent.academia.edu/Crist%C3%B3balBueno?f_ri=620049","photo":"https://0.academia-photos.com/109209391/25600463/24309347/s65_crist_bal.bueno.jpg"}</script></span></span></li><li class="js-paper-rank-work_66906305 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="66906305"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 66906305, container: ".js-paper-rank-work_66906305", }); });</script></li><li class="js-percentile-work_66906305 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 66906305; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_66906305"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_66906305 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="66906305"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 66906305; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=66906305]").text(description); $(".js-view-count-work_66906305").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_66906305").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="66906305"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">18</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="8999" rel="nofollow" href="https://www.academia.edu/Documents/in/Kidney_diseases">Kidney diseases</a>, <script data-card-contents-for-ri="8999" type="text/json">{"id":8999,"name":"Kidney diseases","url":"https://www.academia.edu/Documents/in/Kidney_diseases?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="71399" rel="nofollow" href="https://www.academia.edu/Documents/in/Hypertension">Hypertension</a>, <script data-card-contents-for-ri="71399" type="text/json">{"id":71399,"name":"Hypertension","url":"https://www.academia.edu/Documents/in/Hypertension?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="74780" rel="nofollow" href="https://www.academia.edu/Documents/in/Mutation">Mutation</a><script data-card-contents-for-ri="74780" type="text/json">{"id":74780,"name":"Mutation","url":"https://www.academia.edu/Documents/in/Mutation?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=66906305]'), work: {"id":66906305,"title":"Uric acid and cardiovascular risk","created_at":"2022-01-02T23:30:21.324-08:00","url":"https://www.academia.edu/66906305/Uric_acid_and_cardiovascular_risk?f_ri=620049","dom_id":"work_66906305","summary":"n engl j med 360;5 nejm.org january 29, 2009 538 Zaman K, Roy E, Arifeen SE, et al. Effectiveness of maternal 1. influenza immunization in mothers and infants. N Engl J Med 2008;359:1555-64. Ali HM, Scott R, Toms GL. The effect of foster feeding and 2. bottle feeding expressed breast-milk on the susceptibility of guinea-pig infants to influenza virus. Br J Exp Pathol 1989;70: 183-91. Chantry CJ, Howard CR, Auinger P. Full breastfeeding dura3. tion and associated decrease in respiratory tract infection in US children. Pediatrics 2006;117:425-32.","downloadable_attachments":[],"ordered_authors":[{"id":109209391,"first_name":"Cristóbal","last_name":"Bueno","domain_name":"independent","page_name":"CristóbalBueno","display_name":"Cristóbal Bueno","profile_url":"https://independent.academia.edu/Crist%C3%B3balBueno?f_ri=620049","photo":"https://0.academia-photos.com/109209391/25600463/24309347/s65_crist_bal.bueno.jpg"}],"research_interests":[{"id":8999,"name":"Kidney diseases","url":"https://www.academia.edu/Documents/in/Kidney_diseases?f_ri=620049","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=620049","nofollow":true},{"id":71399,"name":"Hypertension","url":"https://www.academia.edu/Documents/in/Hypertension?f_ri=620049","nofollow":true},{"id":74780,"name":"Mutation","url":"https://www.academia.edu/Documents/in/Mutation?f_ri=620049","nofollow":true},{"id":191815,"name":"Biological evolution","url":"https://www.academia.edu/Documents/in/Biological_evolution?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":227305,"name":"Hyperuricemia","url":"https://www.academia.edu/Documents/in/Hyperuricemia?f_ri=620049"},{"id":309088,"name":"Uric Acid","url":"https://www.academia.edu/Documents/in/Uric_Acid?f_ri=620049"},{"id":313857,"name":"Risk Factor","url":"https://www.academia.edu/Documents/in/Risk_Factor?f_ri=620049"},{"id":389732,"name":"New England","url":"https://www.academia.edu/Documents/in/New_England?f_ri=620049"},{"id":516151,"name":"Genetic Polymorphism","url":"https://www.academia.edu/Documents/in/Genetic_Polymorphism?f_ri=620049"},{"id":519447,"name":"Hominidae","url":"https://www.academia.edu/Documents/in/Hominidae?f_ri=620049"},{"id":559242,"name":"Cardiovascular Diseases","url":"https://www.academia.edu/Documents/in/Cardiovascular_Diseases?f_ri=620049"},{"id":568482,"name":"Biological markers","url":"https://www.academia.edu/Documents/in/Biological_markers?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":1161066,"name":"New England Journalof Medicine","url":"https://www.academia.edu/Documents/in/New_England_Journalof_Medicine?f_ri=620049"},{"id":1238050,"name":"Allopurinol","url":"https://www.academia.edu/Documents/in/Allopurinol?f_ri=620049"},{"id":3763225,"name":"Medical and Health Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_13546921" data-work_id="13546921" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13546921/Predictors_of_violence_in_young_tourists_a_comparative_study_of_British_German_and_Spanish_holidaymakers">Predictors of violence in young tourists: a comparative study of British, German and Spanish holidaymakers</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Background: International youth holiday resorts feature many of the key risk factors for violence, including large numbers of bars and nightclubs and high levels of substance use. However, little information currently exists on the extent... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_13546921" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Background: International youth holiday resorts feature many of the key risk factors for violence, including large numbers of bars and nightclubs and high levels of substance use. However, little information currently exists on the extent of violence amongst holidaymakers or factors that increase risks of involvement in fights on holiday. Methods: A cross-sectional comparative survey of 3003 British, German and Spanish holidaymakers aged 16-35 years, undertaken in the departure areas of Ibiza and Majorca (Spain) airports. Results: Nightlife was the most common reason for destination choice in both locations. Overall, more than half of participants reported drinking to drunkenness at least 2 days per week during their holiday (59.3% Majorca, 58.0% Ibiza; significantly lower in Spanish participants in both locations). Levels of illicit drug use were highest in Ibiza and in British and Spanish holidaymakers. Levels of violence were highest in Majorca, where 6.4% of participants reported involvement in a fight, compared with 2.8% in Ibiza. However, after controlling for confounding factors, holiday destination was not a significant predictor of violence. Predictors of fighting were being male, young, British, frequent drunkenness and use of cannabis or cocaine during the holiday. Use of ecstasy on holiday was associated with not being involved in violence. Conclusions: High levels of substance use contribute to violence being a relatively common feature of young people's visits to international holiday resorts. To protect the health and well-being of holidaymakers and local populations in popular resorts, violence and substance use prevention must adapt to an increasingly globalized nightlife.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13546921" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="3ef5e034b838c1096ac1aa44c83d0f27" rel="nofollow" data-download="{"attachment_id":45224208,"asset_id":13546921,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45224208/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32736960" href="https://independent.academia.edu/AmadorCalafat">Amador Calafat</a><script data-card-contents-for-user="32736960" type="text/json">{"id":32736960,"first_name":"Amador","last_name":"Calafat","domain_name":"independent","page_name":"AmadorCalafat","display_name":"Amador Calafat","profile_url":"https://independent.academia.edu/AmadorCalafat?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_13546921 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="13546921"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 13546921, container: ".js-paper-rank-work_13546921", }); 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$(".js-view-count[data-work-id=13546921]").text(description); $(".js-view-count-work_13546921").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_13546921").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="13546921"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">21</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="1697" rel="nofollow" href="https://www.academia.edu/Documents/in/Violence">Violence</a>, <script data-card-contents-for-ri="1697" type="text/json">{"id":1697,"name":"Violence","url":"https://www.academia.edu/Documents/in/Violence?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="16288" rel="nofollow" href="https://www.academia.edu/Documents/in/Public_Health">Public Health</a>, <script data-card-contents-for-ri="16288" type="text/json">{"id":16288,"name":"Public Health","url":"https://www.academia.edu/Documents/in/Public_Health?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="33666" rel="nofollow" href="https://www.academia.edu/Documents/in/European_Public_Health_Policies">European Public Health Policies</a><script data-card-contents-for-ri="33666" type="text/json">{"id":33666,"name":"European Public Health Policies","url":"https://www.academia.edu/Documents/in/European_Public_Health_Policies?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=13546921]'), work: {"id":13546921,"title":"Predictors of violence in young tourists: a comparative study of British, German and Spanish holidaymakers","created_at":"2015-07-02T08:31:43.909-07:00","url":"https://www.academia.edu/13546921/Predictors_of_violence_in_young_tourists_a_comparative_study_of_British_German_and_Spanish_holidaymakers?f_ri=620049","dom_id":"work_13546921","summary":"Background: International youth holiday resorts feature many of the key risk factors for violence, including large numbers of bars and nightclubs and high levels of substance use. However, little information currently exists on the extent of violence amongst holidaymakers or factors that increase risks of involvement in fights on holiday. Methods: A cross-sectional comparative survey of 3003 British, German and Spanish holidaymakers aged 16-35 years, undertaken in the departure areas of Ibiza and Majorca (Spain) airports. Results: Nightlife was the most common reason for destination choice in both locations. Overall, more than half of participants reported drinking to drunkenness at least 2 days per week during their holiday (59.3% Majorca, 58.0% Ibiza; significantly lower in Spanish participants in both locations). Levels of illicit drug use were highest in Ibiza and in British and Spanish holidaymakers. Levels of violence were highest in Majorca, where 6.4% of participants reported involvement in a fight, compared with 2.8% in Ibiza. However, after controlling for confounding factors, holiday destination was not a significant predictor of violence. Predictors of fighting were being male, young, British, frequent drunkenness and use of cannabis or cocaine during the holiday. Use of ecstasy on holiday was associated with not being involved in violence. Conclusions: High levels of substance use contribute to violence being a relatively common feature of young people's visits to international holiday resorts. To protect the health and well-being of holidaymakers and local populations in popular resorts, violence and substance use prevention must adapt to an increasingly globalized nightlife.","downloadable_attachments":[{"id":45224208,"asset_id":13546921,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32736960,"first_name":"Amador","last_name":"Calafat","domain_name":"independent","page_name":"AmadorCalafat","display_name":"Amador Calafat","profile_url":"https://independent.academia.edu/AmadorCalafat?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":1697,"name":"Violence","url":"https://www.academia.edu/Documents/in/Violence?f_ri=620049","nofollow":true},{"id":16288,"name":"Public Health","url":"https://www.academia.edu/Documents/in/Public_Health?f_ri=620049","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=620049","nofollow":true},{"id":33666,"name":"European Public Health Policies","url":"https://www.academia.edu/Documents/in/European_Public_Health_Policies?f_ri=620049","nofollow":true},{"id":40516,"name":"Spain","url":"https://www.academia.edu/Documents/in/Spain?f_ri=620049"},{"id":50576,"name":"Germany","url":"https://www.academia.edu/Documents/in/Germany?f_ri=620049"},{"id":57928,"name":"Travel","url":"https://www.academia.edu/Documents/in/Travel?f_ri=620049"},{"id":72353,"name":"Substance Use","url":"https://www.academia.edu/Documents/in/Substance_Use?f_ri=620049"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=620049"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049"},{"id":227342,"name":"Alcohol Consumption","url":"https://www.academia.edu/Documents/in/Alcohol_Consumption?f_ri=620049"},{"id":279027,"name":"European","url":"https://www.academia.edu/Documents/in/European?f_ri=620049"},{"id":291274,"name":"Great Britain","url":"https://www.academia.edu/Documents/in/Great_Britain?f_ri=620049"},{"id":404000,"name":"Cross Section","url":"https://www.academia.edu/Documents/in/Cross_Section?f_ri=620049"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=620049"},{"id":413192,"name":"Sex Factors","url":"https://www.academia.edu/Documents/in/Sex_Factors?f_ri=620049"},{"id":546419,"name":"Age Factors","url":"https://www.academia.edu/Documents/in/Age_Factors?f_ri=620049"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049"},{"id":999544,"name":"Illicit Drug Use","url":"https://www.academia.edu/Documents/in/Illicit_Drug_Use?f_ri=620049"},{"id":1034181,"name":"Cross Sectional Studies","url":"https://www.academia.edu/Documents/in/Cross_Sectional_Studies?f_ri=620049"},{"id":1423077,"name":"Substance-Related Disorders","url":"https://www.academia.edu/Documents/in/Substance-Related_Disorders?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_16511598" data-work_id="16511598" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/16511598/Cancer_of_the_larynx">Cancer of the larynx</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">In Europe, laryngeal cancer accounts for only 2 Á/5% of all cancers, the incidence being much higher among males than among females. Smoke and alcohol represent the major behavioural risk factors. Several carcinogens, occupations and... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_16511598" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">In Europe, laryngeal cancer accounts for only 2 Á/5% of all cancers, the incidence being much higher among males than among females. Smoke and alcohol represent the major behavioural risk factors. Several carcinogens, occupations and vitamin deficiencies have been associated with laryngeal cancer. A genetic susceptibility to environmental risk factors and carcinogens is recognized. Hoarseness is the main symptom for which patients call for medical consultation. Mucosa is the most common histologic site of the primary lesions considered in the present chapter. Nodal involvement, the site and volume of the primary tumour, and some genes expression represent the major prognostic factors. A high death rate for not cancer-related events is to be pointed out. The locoregional extent of the disease determines the success of cure. Surgery and radiotherapy represent the main therapeutic options. The choice between these two procedures is often controversial. #</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/16511598" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="84c058dd6dfd445f7249ac47d5f0a6f5" rel="nofollow" data-download="{"attachment_id":42453297,"asset_id":16511598,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42453297/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="35750995" href="https://independent.academia.edu/MarcoMerlano">Marco Merlano</a><script data-card-contents-for-user="35750995" type="text/json">{"id":35750995,"first_name":"Marco","last_name":"Merlano","domain_name":"independent","page_name":"MarcoMerlano","display_name":"Marco Merlano","profile_url":"https://independent.academia.edu/MarcoMerlano?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_16511598 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="16511598"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 16511598, container: ".js-paper-rank-work_16511598", }); });</script></li><li class="js-percentile-work_16511598 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 16511598; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_16511598"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_16511598 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="16511598"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 16511598; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=16511598]").text(description); $(".js-view-count-work_16511598").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_16511598").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="16511598"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">6</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="27784" rel="nofollow" href="https://www.academia.edu/Documents/in/Gene_expression">Gene expression</a>, <script data-card-contents-for-ri="27784" type="text/json">{"id":27784,"name":"Gene expression","url":"https://www.academia.edu/Documents/in/Gene_expression?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="192721" rel="nofollow" href="https://www.academia.edu/Documents/in/Risk_factors">Risk factors</a>, <script data-card-contents-for-ri="192721" type="text/json">{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="234658" rel="nofollow" href="https://www.academia.edu/Documents/in/Laryngeal_Cancer">Laryngeal Cancer</a>, <script data-card-contents-for-ri="234658" type="text/json">{"id":234658,"name":"Laryngeal Cancer","url":"https://www.academia.edu/Documents/in/Laryngeal_Cancer?f_ri=620049","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="620049" rel="nofollow" href="https://www.academia.edu/Documents/in/Risk_Factors-1">Risk Factors</a><script data-card-contents-for-ri="620049" type="text/json">{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=16511598]'), work: {"id":16511598,"title":"Cancer of the larynx","created_at":"2015-10-06T07:48:12.005-07:00","url":"https://www.academia.edu/16511598/Cancer_of_the_larynx?f_ri=620049","dom_id":"work_16511598","summary":"In Europe, laryngeal cancer accounts for only 2 Á/5% of all cancers, the incidence being much higher among males than among females. Smoke and alcohol represent the major behavioural risk factors. Several carcinogens, occupations and vitamin deficiencies have been associated with laryngeal cancer. A genetic susceptibility to environmental risk factors and carcinogens is recognized. Hoarseness is the main symptom for which patients call for medical consultation. Mucosa is the most common histologic site of the primary lesions considered in the present chapter. Nodal involvement, the site and volume of the primary tumour, and some genes expression represent the major prognostic factors. A high death rate for not cancer-related events is to be pointed out. The locoregional extent of the disease determines the success of cure. Surgery and radiotherapy represent the main therapeutic options. The choice between these two procedures is often controversial. #","downloadable_attachments":[{"id":42453297,"asset_id":16511598,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":35750995,"first_name":"Marco","last_name":"Merlano","domain_name":"independent","page_name":"MarcoMerlano","display_name":"Marco Merlano","profile_url":"https://independent.academia.edu/MarcoMerlano?f_ri=620049","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":27784,"name":"Gene expression","url":"https://www.academia.edu/Documents/in/Gene_expression?f_ri=620049","nofollow":true},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=620049","nofollow":true},{"id":234658,"name":"Laryngeal Cancer","url":"https://www.academia.edu/Documents/in/Laryngeal_Cancer?f_ri=620049","nofollow":true},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=620049","nofollow":true},{"id":1153872,"name":"Genetic Susceptibility","url":"https://www.academia.edu/Documents/in/Genetic_Susceptibility?f_ri=620049"},{"id":2195752,"name":"Critical Reviews","url":"https://www.academia.edu/Documents/in/Critical_Reviews?f_ri=620049"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_13852363" data-work_id="13852363" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13852363/Posttraumatic_stress_disorder_A_state_of_the_science_review">Posttraumatic stress disorder: A state-of-the-science review</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">This article reviews the state-of-the-art research in posttraumatic stress disorder (PTSD) from several perspectives: (1) Sex differences: PTSD is more frequent among women, who tend to have different types of precipitating traumas and... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_13852363" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">This article reviews the state-of-the-art research in posttraumatic stress disorder (PTSD) from several perspectives: (1) Sex differences: PTSD is more frequent among women, who tend to have different types of precipitating traumas and higher rates of comorbid panic disorder and agoraphobia than do men. (2) Risk and resilience: The presence of Group C symptoms after exposure to a disaster or act of terrorism may predict the development of PTSD as well as comorbid diagnoses. (3) Impact of trauma in early life: Persistent increases in CRF concentration are associated with early life trauma and PTSD, and may be reversed with paroxetine treatment. (4) Imaging studies: Intriguing findings in treated and untreated depressed patients may serve as a paradigm of failed brain adaptation to chronic emotional stress and anxiety disorders. (5) Neural circuits and memory: Hippocampal volume appears to be selectively decreased and hippocampal function impaired among PTSD patients. (6) Cognitive behavioral approaches: Prolonged exposure therapy, a readily disseminated treatment modality, is effective in modifying the negative cognitions that are frequent among PTSD patients. In the future, it would be useful to assess the validity of the PTSD construct, elucidate genetic and experiential contributing factors (and their complex interrelationships), clarify the mechanisms of action for different treatments used in PTSD, discover ways to predict which treatments (or treatment combinations) will be successful for a given individual, develop an operational definition of remission in PTSD, and explore ways to disseminate effective evidence-based treatments for this condition.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13852363" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="6b44d94a59ed80632682f9ba308bfed9" rel="nofollow" data-download="{"attachment_id":44878585,"asset_id":13852363,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44878585/download_file?st=MTczOTk5NjI5Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32945687" href="https://miami.academia.edu/CharlesNemeroff">Charles Nemeroff</a><script data-card-contents-for-user="32945687" type="text/json">{"id":32945687,"first_name":"Charles","last_name":"Nemeroff","domain_name":"miami","page_name":"CharlesNemeroff","display_name":"Charles Nemeroff","profile_url":"https://miami.academia.edu/CharlesNemeroff?f_ri=620049","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_13852363 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="13852363"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 13852363, container: ".js-paper-rank-work_13852363", }); 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In the future, it would be useful to assess the validity of the PTSD construct, elucidate genetic and experiential contributing factors (and their complex interrelationships), clarify the mechanisms of action for different treatments used in PTSD, discover ways to predict which treatments (or treatment combinations) will be successful for a given individual, develop an operational definition of remission in PTSD, and explore ways to disseminate effective evidence-based treatments for this condition.","downloadable_attachments":[{"id":44878585,"asset_id":13852363,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32945687,"first_name":"Charles","last_name":"Nemeroff","domain_name":"miami","page_name":"CharlesNemeroff","display_name":"Charles 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