Injection Information | Enbrel® (etanercept)

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ENBREL can be taken with methotrexate or used alone.</span> <span class="readmore"><a href="javascript:void(0);" class="quantum-link quantum-indications__read-more-link seeMore">Read more</a></span> </p> <div class="quantum-indications__copy quantum-indications__copy--read-more quantum-long-form-text" style="display: none;"> <p> <span class="medium">ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with moderately to severely active rheumatoid arthritis. ENBREL can be taken with methotrexate or used alone.</span> </p> <p> <span class="medium">ENBREL is indicated for chronic moderate to severe plaque psoriasis (PsO) in children 4 years of age or older and adults who may benefit from taking injections or pills (systemic therapy) or phototherapy (ultraviolet light).</span> </p> <p> <span class="medium">ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in adult patients with psoriatic arthritis. ENBREL can be used with or without methotrexate.</span> </p> <p> <span class="medium">ENBREL is indicated for reducing signs and symptoms in patients with active ankylosing spondylitis.</span> </p> <p> <span class="medium">ENBREL is indicated for reducing signs and symptoms of moderately to severely active polyarticular juvenile idiopathic arthritis (pJIA) in children 2 years of age or older.</span> </p> <p class="mb-0"> <span class="medium">ENBREL is indicated for active juvenile psoriatic arthritis (JPsA) in children 2 years of age or older.</span> </p> <p class="indiction-close"><a href="javascript:void(0);" class="quantum-link quantum-indications__read-less-link seeLess">close</a></p> </div> <button class="quantum-button quantum-button--tertiary quantum-indications__close quantum-button--icon-only" id="indicationClose" type="button"> <svg class="quantum-icon quantum-button__icon"> <use xlink:href="-/media/Themes/Amgen/Enbrel-com-Redesign/Enbrel-com-Redesign/Images/Content/Common/quantum.svg#close-light"></use> </svg> </button> </div> </div> <script> indicationURL='/MyApi/Custom/IndicationCL/CloseIndication'; 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class="item4 even"> <div class="field-link"><a href="javascript:void(0)" data-variantitemid="{9C6881CA-2B80-4446-ADBC-FADF5A8D1318}" data-variantfieldname="Link" class="indication-link">Indications</a> </div> </li>  <li class="item6 even last"> <div class="field-link"><a href="https://www.enbrelpro.com/" rel="noopener noreferrer" data-variantitemid="{966A9D7C-FA48-473D-AA8F-80F2E5F6C7FA}" data-variantfieldname="Link" class="ext-hcp-lnk" target="_blank" data-click-type='outbound' data-click-text='Healthcare Professionals'>Healthcare<br class="mobileOnly"/> Professionals</a></div> </li> </div> </ul> </div> </div> </div> </div> </div> <div class="quantum-header__right "> <div class="quantum-header__menu"> <nav class="quantum-drop-down-menu"> <ul class="quantum-drop-down-menu__list"> <li class="quantum-drop-down-menu__list-item submenu-dropdown condition-dropdown"> <a href="/rheumatoid-arthritis" class=" quantum-drop-down-menu__link navigate gtm-header gtm-navigation-click" ca1="" data-value="FLItem-1" > <span class="quantum-drop-down-menu__link-text"> Choose Your Condition </span> <svg class="quantum-icon quantum-button__icon desktop-break"> <use xlink:href="-/media/Themes/Global/Global/Global/images/amgen.svg#angle-down-regular"></use> </svg> <svg class="quantum-icon quantum-drop-down-menu__link-icon quantum-drop-down-menu__link-icon--expand-dropdown"> <use xlink:href="-/media/Themes/Global/Global/Global/images/amgen.svg#plus-circle-regular"></use> </svg> <svg class="quantum-icon quantum-drop-down-menu__link-icon quantum-drop-down-menu__link-icon--collapse-dropdown"> <use xlink:href="-/media/Themes/Global/Global/Global/images/amgen.svg#minus-circle-regular"></use> </svg> </a> <ul class="quantum-drop-down-menu__menu"> <li class="quantum-drop-down-menu__menu-list-item"> <a href="/rheumatoid-arthritis" class="quantum-drop-down-menu__menu-link " data-value="FLItem-1-SLItem-1"> Rheumatoid Arthritis </a> </li> <li class="quantum-drop-down-menu__menu-list-item"> <a href="/psoriatic-arthritis" class="quantum-drop-down-menu__menu-link navigate gtm-header gtm-navigation-click " data-value="FLItem-1-SLItem-2"> Adult Psoriatic Arthritis </a> </li> <li class="quantum-drop-down-menu__menu-list-item"> <a href="/ankylosing-spondylitis" class="quantum-drop-down-menu__menu-link " data-value="FLItem-1-SLItem-3"> Ankylosing Spondylitis </a> </li> <li class="quantum-drop-down-menu__menu-list-item"> <a href="/juvenile-idiopathic-arthritis" class="quantum-drop-down-menu__menu-link " data-value="FLItem-1-SLItem-4"> Juvenile Idiopathic Arthritis </a> </li> <li class="quantum-drop-down-menu__menu-list-item"> <a href="/plaque-psoriasis" class="quantum-drop-down-menu__menu-link navigate gtm-header gtm-navigation-click " data-value="FLItem-1-SLItem-5"> Plaque Psoriasis </a> </li> </ul> </li> <li class="quantum-drop-down-menu__list-item submenu-dropdown"> <a class="quantum-drop-down-menu__link navigate gtm-header gtm-navigation-click" menu-name="getting and taking enbrel" menu-type="main" href="" target="" data-value="FLItem-2"> <span class="quantum-drop-down-menu__link-text">Getting & Taking ENBREL</span> <svg class="quantum-icon quantum-button__icon desktop-break"> <use xlink:href="-/media/Themes/Global/Global/Global/images/amgen.svg#angle-down-regular"></use> </svg> <svg class="quantum-icon quantum-drop-down-menu__link-icon quantum-drop-down-menu__link-icon--expand-dropdown"> <use xlink:href="-/media/Themes/Global/Global/Global/images/amgen.svg#plus-circle-regular"></use> </svg> <svg class="quantum-icon quantum-drop-down-menu__link-icon quantum-drop-down-menu__link-icon--collapse-dropdown"> <use xlink:href="-/media/Themes/Global/Global/Global/images/amgen.svg#minus-circle-regular"></use> </svg> </a> <ul class="quantum-drop-down-menu__menu"> <li class="quantum-drop-down-menu__menu-list-item"> <a href="/taking-enbrel/getting-your-enbrel" class="quantum-drop-down-menu__menu-link navigate gtm-header gtm-navigation-click " menu-name="side effects" menu-type="main" data-value="FLItem-2-SLItem-6"> Getting Your ENBREL </a> </li> <li class="quantum-drop-down-menu__menu-list-item"> <a href="/taking-enbrel/injection-info" class="quantum-drop-down-menu__menu-link navigate gtm-header gtm-navigation-click " menu-name="side effects" menu-type="main" data-value="FLItem-2-SLItem-7"> Injection Info </a> </li> <li class="quantum-drop-down-menu__menu-list-item"> <a href="/taking-enbrel/caring-for-yourself" class="quantum-drop-down-menu__menu-link navigate gtm-header gtm-navigation-click " menu-name="side effects" menu-type="main" data-value="FLItem-2-SLItem-8"> Caring for Yourself </a> </li> <li class="quantum-drop-down-menu__menu-list-item"> <a href="/taking-enbrel/faq" class="quantum-drop-down-menu__menu-link navigate gtm-header gtm-navigation-click " menu-name="side effects" menu-type="main" data-value="FLItem-2-SLItem-9"> Frequently Asked Questions </a> </li> </ul> </li> <li class="quantum-drop-down-menu__list-item submenu-dropdown"> <a class="quantum-drop-down-menu__link navigate gtm-header gtm-navigation-click" menu-name="support from enbrel" menu-type="main" href="/support" target="" data-value="FLItem-3"> <span class="quantum-drop-down-menu__link-text">Support & Resources</span> <svg class="quantum-icon quantum-button__icon desktop-break"> <use xlink:href="-/media/Themes/Global/Global/Global/images/amgen.svg#angle-down-regular"></use> </svg> <svg class="quantum-icon quantum-drop-down-menu__link-icon quantum-drop-down-menu__link-icon--expand-dropdown"> <use xlink:href="-/media/Themes/Global/Global/Global/images/amgen.svg#plus-circle-regular"></use> </svg> <svg class="quantum-icon quantum-drop-down-menu__link-icon quantum-drop-down-menu__link-icon--collapse-dropdown"> <use xlink:href="-/media/Themes/Global/Global/Global/images/amgen.svg#minus-circle-regular"></use> </svg> </a> <ul class="quantum-drop-down-menu__menu"> <li class="quantum-drop-down-menu__menu-list-item"> <a href="/support" class="quantum-drop-down-menu__menu-link " data-value="FLItem-3-SLItem-10"> ENBREL Co-Pay Card </a> </li> <li class="quantum-drop-down-menu__menu-list-item"> <a href="/support/amgen-nurse-partner" class="quantum-drop-down-menu__menu-link " data-value="FLItem-3-SLItem-11"> Amgen Nurse Partners </a> </li> <li class="quantum-drop-down-menu__menu-list-item"> <a href="/support/traveling-with-enbrel" class="quantum-drop-down-menu__menu-link " data-value="FLItem-3-SLItem-12"> Traveling with ENBREL </a> </li> </ul> </li> <li class="quantum-drop-down-menu__list-item mr-0"> <a class="quantum-drop-down-menu__link navigate gtm-header gtm-navigation-click" menu-name="Enbrel-co-pay-card" menu-type="main" href="/support" target="" data-value="FLItem-4"> <span class="quantum-drop-down-menu__link-text">ENBREL Co-Pay Card</span> </a> </li> <li class="quantum-drop-down-menu__list-item mobile-only enbrel-es"> <a class="quantum-drop-down-menu__link navigate gtm-navigation-click" menu-name="prescribing information" menu-type="main" href="/en-espanol" target="" data-value="FLItem-5"> <span class="quantum-drop-down-menu__link-text">En Espanol</span> </a> </li> <li class="quantum-drop-down-menu__list-item "> </li> </ul> <ul class="quantum-drop-down-menu__top-nav-list "> </ul> </nav> </div> <div class="quantum-header__mobile-content "> <button class="quantum-button quantum-button--tertiary quantum-header__icon-button quantum-button--large quantum-button--icon-only " type="button"> <svg class="quantum-icon quantum-button__icon"> <use xlink:href="-/media/Themes/Global/Global/Global/images/amgen.svg#search-regular"></use> </svg> </button> <button class="quantum-button quantum-button--tertiary quantum-header__icon-button quantum-header__menu-trigger quantum-header__menu-trigger--expand-menu quantum-button--large quantum-button--icon-only" type="button"> <svg class="quantum-icon quantum-button__icon"> <use xlink:href="-/media/Themes/Global/Global/Global/images/amgen.svg#bars-regular"></use> </svg> </button> <button class="quantum-button quantum-button--tertiary quantum-header__icon-button quantum-header__menu-trigger quantum-header__menu-trigger--collapse-menu quantum-button--large quantum-button--icon-only" type="button"> <svg class="quantum-icon quantum-button__icon"> <use xlink:href="-/media/Themes/Global/Global/Global/images/amgen.svg#close-light"></use> </svg> </button> </div> </div> </div> </div> </header> <div class="hero-div"> </div> <div class="banner-div"> </div> <div class="component container col-12 full-width enbrel-logo-mobile max-width mobile-only"> <div class="component-content" > <div class="row component column-splitter"> <div class="col-6 col-sm-6 col-md-4 p0"> <a class="quantum-header__logo d-none d-sm-block gtm-header" href="/"> <img src="-/media/Themes/Amgen/Enbrel-com-Redesign-new/Enbrel-com-Redesign-new/Images/Logos/enbrel-header-logo.svg?la=en&hash=AD3C2CAA18169CCEF4C4A0CB955E7BA5" class="quantum-header__logo" rel="preload" fetchpriority="high" alt="ENBREL® header logo" /> </a> <a class="quantum-header__logo d-block d-sm-none gtm-header" href="/" > <img src="-/media/Themes/Amgen/Enbrel-com-Redesign-new/Enbrel-com-Redesign-new/Images/Logos/enbrel-header-logo.svg?la=en&hash=AD3C2CAA18169CCEF4C4A0CB955E7BA5" class="quantum-header__logo" rel="preload" fetchpriority="high" alt="ENBREL® header logo" /> </a> </div> <div class="col-6 col-sm-6 col-md-8 desktop-only p0"> <div class="quantum-header " id=""> <div class="quantum-header__inner"> <div class="quantum-header__left "> </div> <div class="quantum-header__right "> <div class="quantum-header__menu"> <nav class="quantum-drop-down-menu"> <ul class="quantum-drop-down-menu__list"> <li class="quantum-drop-down-menu__list-item submenu-dropdown condition-dropdown"> <a href="/rheumatoid-arthritis" class=" quantum-drop-down-menu__link navigate gtm-header gtm-navigation-click" ca1="" data-value="FLItem-1" > <span class="quantum-drop-down-menu__link-text"> Choose your Condition </span> <svg class="quantum-icon quantum-button__icon desktop-break"> <use xlink:href="-/media/Themes/Global/Global/Global/images/amgen.svg#angle-down-regular"></use> </svg> <svg class="quantum-icon quantum-drop-down-menu__link-icon quantum-drop-down-menu__link-icon--expand-dropdown"> <use xlink:href="-/media/Themes/Global/Global/Global/images/amgen.svg#plus-circle-regular"></use> </svg> <svg class="quantum-icon quantum-drop-down-menu__link-icon quantum-drop-down-menu__link-icon--collapse-dropdown"> <use xlink:href="-/media/Themes/Global/Global/Global/images/amgen.svg#minus-circle-regular"></use> </svg> </a> <ul class="quantum-drop-down-menu__menu"> <li class="quantum-drop-down-menu__menu-list-item"> <a href="/rheumatoid-arthritis" class="quantum-drop-down-menu__menu-link " data-value="FLItem-1-SLItem-1"> Rheumatoid Arthritis </a> </li> <li class="quantum-drop-down-menu__menu-list-item"> <a href="/psoriatic-arthritis" class="quantum-drop-down-menu__menu-link navigate gtm-header gtm-navigation-click " data-value="FLItem-1-SLItem-2"> Adult Psoriatic Arthritis </a> </li> <li class="quantum-drop-down-menu__menu-list-item"> <a href="/ankylosing-spondylitis" class="quantum-drop-down-menu__menu-link " data-value="FLItem-1-SLItem-3"> Ankylosing Spondylitis </a> </li> <li class="quantum-drop-down-menu__menu-list-item"> <a href="/juvenile-idiopathic-arthritis" class="quantum-drop-down-menu__menu-link " data-value="FLItem-1-SLItem-4"> Juvenile Idiopathic Arthritis </a> </li> <li class="quantum-drop-down-menu__menu-list-item"> <a href="/plaque-psoriasis" class="quantum-drop-down-menu__menu-link navigate gtm-header gtm-navigation-click " data-value="FLItem-1-SLItem-5"> Plaque Psoriasis </a> </li> </ul> </li> </ul> <ul class="quantum-drop-down-menu__top-nav-list "> </ul> </nav> </div> <div class="quantum-header__mobile-content "> <button class="quantum-button quantum-button--tertiary quantum-header__icon-button quantum-button--large quantum-button--icon-only " type="button"> <svg class="quantum-icon quantum-button__icon"> <use xlink:href="-/media/Themes/Global/Global/Global/images/amgen.svg#search-regular"></use> </svg> </button> <button class="quantum-button quantum-button--tertiary quantum-header__icon-button quantum-header__menu-trigger quantum-header__menu-trigger--expand-menu quantum-button--large quantum-button--icon-only" type="button"> <svg class="quantum-icon quantum-button__icon"> <use xlink:href="-/media/Themes/Global/Global/Global/images/amgen.svg#bars-regular"></use> </svg> </button> <button class="quantum-button quantum-button--tertiary quantum-header__icon-button quantum-header__menu-trigger quantum-header__menu-trigger--collapse-menu quantum-button--large quantum-button--icon-only" type="button"> <svg class="quantum-icon quantum-button__icon"> <use xlink:href="-/media/Themes/Global/Global/Global/images/amgen.svg#close-light"></use> </svg> </button> </div> </div> </div> </div> </div> </div> </div> </div> <div class="component container full-width jumplink max-width"> <div class="component-content" > <div class="component link-list"> <div class="component-content"> <ul> <li class="item0 odd first"> <div class="field-link"><a href="/taking-enbrel/getting-your-enbrel" data-variantitemid="{6376E8C8-A33F-411F-A026-667A25964FF8}" data-variantfieldname="Link">GETTING YOUR ENBREL</a></div> </li> <li class="item1 even"> <div class="field-link"><a href="/taking-enbrel/injection-info" data-variantitemid="{CD2C92FD-E5D2-4391-8C98-281218933E98}" data-variantfieldname="Link">INJECTION INFO</a></div> </li> <li class="item2 odd"> <div class="field-link"><a href="/taking-enbrel/caring-for-yourself" data-variantitemid="{838AD95F-4497-443E-B919-2DAFD46E889C}" data-variantfieldname="Link">CARING FOR YOURSELF</a></div> </li> <li class="item3 even last"> <div class="field-link"><a href="/taking-enbrel/faq" data-variantitemid="{EA234725-0B77-4F6A-8814-76C182730353}" data-variantfieldname="Link">FREQUENTLY ASKED QUESTIONS</a></div> </li> </ul> </div> </div> </div> </div> <div class="component container full-width max-width pl-0"> <div class="component-content" > <div class="component plain-html"> <div class="component-content"> <div class="inject-enbrel"> <div class="bor-left"> <h1>How to Inject ENBREL</h1> </div> <p>You have several options for taking ENBREL. You and your doctor will decide which one is right for you.</p> <p>Remember, the following information is intended to provide you with an overview and supplemental information about each injection device for ENBREL. They do not replace the Instructions for Use. That’s why it is extremely important that you thoroughly review the Instructions for Use for any device that you plan to use. Those instructions cover everything you need to know about how to use ENBREL.</p> <p>As always, please contact your healthcare provider if you have any questions.</p> </div> </div> </div> </div> </div> <div class="component container full-width max-width autoinjector-video" id="how-to-inject-enbrel-sureclick"> <div class="component-content" > <div class="component plain-html"> <div class="component-content"> <h3>SureClick<sup>®</sup> autoinjector</h3> </div> </div> <div class="row component column-splitter"> <div class="col-12 col-md-12 col-lg-6 pl-0"> <div class="component promo"> <div class="component-content"> <div class="promo-left-img"><div class="field-promotext"><p>The SureClick<sup>®</sup> autoinjector allows you to take your ENBREL with the press of a button. Plus it’s designed to make a clicking noise when you start and finish your injection.</p> <p><b>Please note:</b> this device is not for use in children (ages 4-17 years) with chronic moderate to severe plaque psoriasis or children with pJIA or JPsA who weigh less than 138 pounds (63 kg).</p>  <p class="more-information">For more information on the SureClick<sup>®</sup> autoinjector</p> <div class="field-promolink"> <a href="https://www.pi.amgen.com/united_states/enbrel/derm/enbrel_scifu.pdf" rel="noopener noreferrer" target="_blank" data-click-type="download" data-click-text="SureClick® autoinjector - Instruction for use">INSTRUCTION FOR USE</a> </div> <p class="more-information supplemental-text">Download the below supplemental resource to help support you with your injection.</p> </div></div><div class="promo-text"><div class="field-promolink"><a href="/-/media/Themes/Amgen/Enbrel-com-Redesign-new/Enbrel-com-Redesign-new/Documents/USA-916-83999_ENBREL_SureClick_Injection_Overview.pdf" rel="noopener noreferrer" data-variantitemid="{67632A24-6B9A-4260-8242-9F01786373AD}" data-variantfieldname="PromoLink" target="_blank">SURECLICK INJECTION OVERVIEW</a></div></div> </div> </div> </div> <div class="col-12 col-md-12 col-lg-6 p0"> <div> <div class="row mx-0 text-video-container " id=""> <div class="col-12 col-md-6 px-0 p-y-40"> <div class="txt-section "> </div> </div> <div class="col-12 col-md-6 px-0 p-y-40 m-auto"> <div id="videoteaserid" style="position:relative;min-height:100%;max-height:unset" class="video-thumb" data-url-video-id=animatedinjection> <video data-video-id="6364538360112" data-account="6415657469001" data-player="zxxI31O31" data-embed="default" data-application-id class="video-js img-section" controls id="videoplayer-mobile-6364538360112" style="height:inherit"></video> <div class="vd-teasercl"> </div> <script src=//players.brightcove.net/6415657469001/zxxI31O31_default/index.min.js> </script> </div> </div> </div> </div> <div class="component link"> <div class="component-content"> <div class="field-link"><a href="/-/media/Themes/Amgen/Enbrel-com-Redesign-new/Enbrel-com-Redesign-new/Documents/SureClick-Autoinjector-transcript.pdf" rel="noopener noreferrer" data-variantitemid="{AAFC19CD-D751-4C35-8C48-8F72C687E7D1}" data-variantfieldname="Link" target="_blank">READ VIDEO TRANSCRIPT</a></div> </div> </div> </div> </div> </div> </div> <div class="component container full-width max-width autoinjector-video" id="how-to-inject-enbrel-autotouch"> <div class="component-content" > <div class="component plain-html"> <div class="component-content"> <h3>AutoTouch<sup>®</sup> autoinjector</h3> </div> </div> <div class="row component column-splitter"> <div class="col-12 col-md-12 col-lg-6 pl-0"> <div> <div class="row mx-0 text-video-container " id=""> <div class="col-12 col-md-6 px-0 p-y-40"> <div class="txt-section "> </div> </div> <div class="col-12 col-md-6 px-0 p-y-40 m-auto"> <div id="videoteaserid" style="position:relative;min-height:100%;max-height:unset" class="video-thumb" data-url-video-id=animatedinjection> <video data-video-id="6364536727112" data-account="6415657469001" data-player="zxxI31O31" data-embed="default" data-application-id class="video-js img-section" controls id="videoplayer-mobile-6364536727112" style="height:inherit"></video> <div class="vd-teasercl"> </div> <script src=//players.brightcove.net/6415657469001/zxxI31O31_default/index.min.js> </script> </div> </div> </div> </div> <div class="component link"> <div class="component-content"> <div class="field-link"><a href="/-/media/Themes/Amgen/Enbrel-com-Redesign-new/Enbrel-com-Redesign-new/Documents/AutoTouch-Autoinjector-transcript.pdf" rel="noopener noreferrer" data-variantitemid="{1521B6DB-6E8A-4B3F-B93C-6C283F2D1394}" data-variantfieldname="Link" target="_blank">READ VIDEO TRANSCRIPT</a></div> </div> </div> </div> <div class="col-12 col-md-12 col-lg-6 p0"> <div class="component promo" id="autotouch-promo"> <div class="component-content"> <div class="promo-text"><div class="field-promoicon"><img src="-/media/Themes/Amgen/Enbrel-com-Redesign-new/Enbrel-com-Redesign-new/Images/Content/Dekstop/Injection-info/autotouch-tips.jpg?h=201&iar=0&w=260&hash=E8DD8C30E9280B1FE1EBCD959F52641D" class="lozad" alt="group-7-copy-2" width="260" height="201" data-variantfieldname="PromoIcon" data-src="-/media/Themes/Amgen/Enbrel-com-Redesign-new/Enbrel-com-Redesign-new/Images/Content/Dekstop/Injection-info/autotouch-tips.jpg" data-variantitemid="{38569077-43D8-48EB-BDEE-430C46B67EE3}" /></div><div class="field-promotext"><p>Need troubleshooting tips for your AutoTouch<sup>®</sup> autoinjector?</p></div></div><div class="promo-icon"><div class="add-mobile field-promoicon2"><img src="-/media/Themes/Amgen/Enbrel-com-Redesign-new/Enbrel-com-Redesign-new/Images/Content/Dekstop/Injection-info/autotouch-videos.png?h=202&iar=0&w=250&hash=0C23E5A3EBF805EFDA7A4D8EABA42F7D" class="lozad" alt="group-7-copy-3" width="250" height="202" data-variantfieldname="PromoIcon2" data-src="-/media/Themes/Amgen/Enbrel-com-Redesign-new/Enbrel-com-Redesign-new/Images/Content/Dekstop/Injection-info/autotouch-videos.png" data-variantitemid="{38569077-43D8-48EB-BDEE-430C46B67EE3}" /></div><div class="field-promolink"><a href="/taking-enbrel/injection-info/ATC-troubleshooting-videos" data-variantitemid="{38569077-43D8-48EB-BDEE-430C46B67EE3}" data-variantfieldname="PromoLink">WATCH VIDEOS</a></div></div> </div> </div> </div> </div> <div class="component promo"> <div class="component-content"> <div class="promo-left-img"><div class="field-promotext"><div class="desktop-hide watch-videos-link"> <p>Need troubleshooting tips for your AutoTouch<sup>®</sup> autoinjector?</p> <a href="/taking-enbrel/injection-info/ATC-troubleshooting-videos" data-variantitemid="{38569077-43D8-48EB-BDEE-430C46B67EE3}" data-variantfieldname="PromoLink" data-click-type="promo" data-click-text="WATCH VIDEOS">WATCH VIDEOS</a> </div> <p>The AutoTouch<sup>®</sup> autoinjector helps you track your injection from start to finish with light and sounds cues.</p> <p><b>Please note:</b> this device is not for use in children (ages 4-17 years) with chronic moderate to severe plaque psoriasis or children with pJIA or JPsA who weigh less than 138 pounds (63 kg).</p> <p class="more-information">For more information on the AutoTouch<sup>®</sup> autoinjector</p></div></div><div class="promo-text"><div class="field-promolink"><a href="https://www.pi.amgen.com/united_states/enbrel/derm/enbrel_ATIFU.pdf" rel="noopener noreferrer" data-variantitemid="{89B2DC8C-C2F1-43EB-A43A-EFD0E3A74C59}" data-variantfieldname="PromoLink" target="_blank">INSTRUCTION FOR USE</a></div></div> </div> </div> </div> </div> <div class="component container full-width max-width autoinjector-video" id="how-to-inject-prefilled-syringe"> <div class="component-content" > <div class="component plain-html"> <div class="component-content"> <h3>Prefilled syringe</h3> </div> </div> <div class="row component column-splitter"> <div class="col-12 col-md-12 col-lg-6 p0 pl-0"> <div class="component promo"> <div class="component-content"> <div class="promo-left-img"><div class="field-promotext"><p>Prefilled syringes are manually injected, which means you control the rate of injection. Each one contains a single dose. </p> <p><b>Please note:</b> the 25-mg syringe is not for use in children (ages 4-17 years) with chronic moderate to severe plaque psoriasis or children with pJIA or JPsA who weigh less than 68 pounds (31 kg).</p> <p><b>Please note:</b> the 50-mg syringe is not for use in children (ages 4-17 years) with chronic moderate to severe plaque psoriasis or children with pJIA or JPsA who weigh less than 138 pounds (63 kg).</p> <p class="more-information">For more information on the Prefilled syringe</p> </div></div><div class="promo-text"><div class="field-promolink"><a href="https://www.pi.amgen.com/united_states/enbrel/derm/enbrel_PFSIFU.pdf" rel="noopener noreferrer" data-variantitemid="{532E208F-F287-4C9E-8D3A-6DE602463410}" data-variantfieldname="PromoLink" target="_blank">INSTRUCTION FOR USE</a></div></div> </div> </div> </div> <div class="col-12 col-md-12 col-lg-6 p0"> <div> <div class="row mx-0 text-video-container " id=""> <div class="col-12 col-md-6 px-0 p-y-40"> <div class="txt-section "> </div> </div> <div class="col-12 col-md-6 px-0 p-y-40 m-auto"> <div id="videoteaserid" style="position:relative;min-height:100%;max-height:unset" class="video-thumb" data-url-video-id=animatedinjection> <video data-video-id="6364537737112" data-account="6415657469001" data-player="zxxI31O31" data-embed="default" data-application-id class="video-js img-section" controls id="videoplayer-mobile-6364537737112" style="height:inherit"></video> <div class="vd-teasercl"> </div> <script src=//players.brightcove.net/6415657469001/zxxI31O31_default/index.min.js> </script> </div> </div> </div> </div> <div class="component link"> <div class="component-content"> <div class="field-link"><a href="/-/media/Themes/Amgen/Enbrel-com-Redesign-new/Enbrel-com-Redesign-new/Documents/Pre-Filled-Syringe-transcript.pdf" rel="noopener noreferrer" data-variantitemid="{39A660AB-898F-4D00-9E93-55835AB249F9}" data-variantfieldname="Link" target="_blank">READ VIDEO TRANSCRIPT</a></div> </div> </div> </div> </div> </div> </div> <div class="component container full-width max-width autoinjector-video" id="how-to-inject-single-dose-vial"> <div class="component-content" > <div class="component plain-html"> <div class="component-content"> <h3>Single-dose vial</h3> </div> </div> <div class="row component column-splitter"> <div class="col-12 col-md-12 col-lg-6 p0"> <div class="component promo"> <div class="component-content"> <div class="promo-left-img"><div class="field-promotext"><p>The single-dose vial is the only option available for children (ages 4-17 years) with chronic moderate to severe plaque psoriasis and children with pJIA or JPsA who weigh less than 68 pounds (31 kg). </p> <p><b>Please note:</b> syringes and needles are not supplied with the single-dose vial, though they are required for injection. They may require a separate prescription from your doctor. We recommend the following:</p> <ul> <li><b>Syringes:</b> 1-mL Luer lock</li> <li><b>Withdrawal needles:</b> 22-gauge, sterile needles with Luer-lock connection. Length: 1.5 inches</li> <li><b>Injection needles:</b> 27-gauge, sterile needles with Luer-lock connection. Length: .5 inch</li> </ul> <p>Two vials may be required to administer the total prescribed dose. Use the same syringe for each vial. The vial does not contain preservatives; therefore, discard unused portions.</p> <p class="more-information">For more information on the single-dose vial</p></div></div><div class="promo-text"><div class="field-promolink"><a href="https://www.pi.amgen.com/united_states/enbrel/derm/enbrel_sdvifu.pdf" rel="noopener noreferrer" data-variantitemid="{78A6E7E6-64EA-4C20-BE34-9A1FECF8E72A}" data-variantfieldname="PromoLink" target="_blank">INSTRUCTION FOR USE</a></div></div> </div> </div> </div> <div class="col-12 col-md-12 col-lg-6 p0"> <div> <div class="row mx-0 text-video-container " id=""> <div class="col-12 col-md-6 px-0 p-y-40"> <div class="txt-section "> </div> </div> <div class="col-12 col-md-6 px-0 p-y-40 m-auto"> <div id="videoteaserid" style="position:relative;min-height:100%;max-height:unset" class="video-thumb" data-url-video-id=animatedinjection> <video data-video-id="6364536992112" data-account="6415657469001" data-player="zxxI31O31" data-embed="default" data-application-id class="video-js img-section" controls id="videoplayer-mobile-6364536992112" style="height:inherit"></video> <div class="vd-teasercl"> </div> <script src=//players.brightcove.net/6415657469001/zxxI31O31_default/index.min.js> </script> </div> </div> </div> </div> <div class="component link"> <div class="component-content"> <div class="field-link"><a href="/-/media/Themes/Amgen/Enbrel-com-Redesign-new/Enbrel-com-Redesign-new/Documents/Single-Dose-Vial-transcript.pdf" rel="noopener noreferrer" data-variantitemid="{005628EC-AD47-43CE-8E68-FC6B55E83266}" data-variantfieldname="Link" target="_blank">READ VIDEO TRANSCRIPT</a></div> </div> </div> </div> </div> </div> </div> <div class="component container full-width"> <div class="component-content" > <div class="component plain-html max-width pl-0"> <div class="component-content"> <div class="faq-header"> <div class="bor-left"> <h1>Frequently Asked Questions</h1> </div> <h4>Here are some frequently asked questions about how to take ENBREL.</h4> </div> </div> </div> <div class="component accordion custom-accordion custom-accordion-outer" data-properties='{"expandOnHover":false,"expandedByDefault":false,"speed":500,"easing":"swing","canOpenMultiple":true,"canToggle":true,"isControlEditable":false}' > <div class="component-content"> <div> <ul class="items"> <li class="item"> <div class="toggle-header" tabindex="-1"> <div class="label"> <div class="component content max-width pl-0"> <div class="component-content"> <div class="field-heading"><div class="bor-left"> <h3>What’s the typical ENBREL dosage for adults?</h3> </div></div> </div> </div> </div> </div> <div class="toggle-content"> <div class="component content max-width"> <div class="component-content"> <div class="field-content"><p class="your-doctor">Your doctor will recommend the best dose and dosing schedule for you. Always follow their instructions. But in general, the recommended dosage of ENBREL is as follows:</p> <div class="accordion-table mobile-hide"> <div class="row accordion-table-heading"> <p>CONDITION</p> <p>RECOMMENDED DOSING</p> </div> <div class="row accordion-table-content"> <p>Adult patients with moderate to severe <b>RA, PsA,</b> or <b>AS</b></p> <p class="pl-35">50 mg, once weekly</p> </div> <div class="row accordion-table-content"> <p>Adult patients with moderate to severe <b>PsO</b></p> <p class="pl-35"><span><b>For the first 3 months:</b> 50 mg, twice weekly</span> <b>After the first 3 months:</b> 50 mg, once weekly</p> </div> </div> <div class="accordion-table desktop-hide"> <div class="row accordion-table-heading"> <p>CONDITION</p> </div> <div class="row accordion-table-content"> <p>Adult patients with moderate to severe <b>RA, PsA,</b> or <b>AS</b></p> <p>Adult patients with moderate to severe <b>PsO</b></p> </div> <div class="row accordion-table-heading recommended-dosing"> <p>RECOMMENDED DOSING</p> </div> <div class="row accordion-table-content"> <p class="pl-35">50 mg, once weekly</p> <p class="pl-35"><span><b>For the first 3 months:</b> 50 mg, twice weekly</span> <b>After the first 3 months:</b> 50 mg, once weekly</p> </div> </div> <div class="accordion-collapse"> <a class="accordion-close" href="javascript:void(0);">COLLAPSE</a> </div></div> </div> </div> </div> </li> <li class="item"> <div class="toggle-header" tabindex="-1"> <div class="label"> <div class="component content max-width pl-0"> <div class="component-content"> <div class="field-heading"><div class="bor-left"> <h3>What’s the typical ENBREL dosage for children?</h3> </div></div> </div> </div> </div> </div> <div class="toggle-content"> <div class="component content max-width"> <div class="component-content"> <div class="field-content"><p class="your-doctor">Your doctor will recommend the best dose and dosing schedule for your child. Always follow their instructions. But in general, the recommended dosage of ENBREL is based on weight, as follows:</p> <div class="accordion-table mobile-hide"> <div class="row accordion-table-heading"> <p>CONDITION</p> <p>RECOMMENDED DOSING</p> </div> <div class="row accordion-table-content"> <p>Pediatric patients (ages 2 years and older) with<br class="desktop-only"> <b>JPsA</b> or moderate to severe <b>pJIA </b></p> <p class="pl-35"><span><b>For patients weighing 138 lb (63 kg) or more:</b> 50 mg, once weekly</span> <b>For patients weighing less than 138 lb (63 kg):</b><br> 0.8 mg per kg, once weekly—with a maximum dose of 50 mg per week</p> </div> <div class="row accordion-table-content"> <p>Pediatric patients (ages 4 years and older)<br class="desktop-only"> with moderate to severe <b>PsO</b></p> <p class="pl-35"><span><b>For patients weighing 138 lb (63 kg) or more:</b> 50 mg, once weekly</span> <b>For patients weighing less than 138 lb (63 kg):</b><br> 0.8 mg per kg, once weekly—with a maximum dose of 50 mg per week</p> </div> </div> <div class="accordion-table desktop-hide"> <div class="row accordion-table-heading"> <p>CONDITION</p> </div> <div class="row accordion-table-content"> <p>Pediatric patients (ages 2 years and older) with<br class="desktop-only"> <b>JPsA</b> or moderate to severe <b>pJIA </b></p> <p>Pediatric patients (ages 4 years and older)<br class="desktop-only"> with moderate to severe <b>PsO</b></p> </div> <div class="row accordion-table-heading recommended-dosing"> <p>RECOMMENDED DOSING</p> </div> <div class="row accordion-table-content"> <p class="pl-35"><span><b>For patients weighing 138 lb (63 kg) or more:</b> 50 mg, once weekly</span> <b>For patients weighing less than 138 lb (63 kg):</b> 0.8 mg per kg, once weekly—with a maximum dose of 50 mg per week</p> </div> <div class="row accordion-table-content"> <p class="pl-35"><span><b>For patients weighing 138 lb (63 kg) or more:</b> 50 mg, once weekly</span> <b>For patients weighing less than 138 lb (63 kg):</b> 0.8 mg per kg, once weekly—with a maximum dose of 50 mg per week</p> </div> </div> <div class="accordion-collapse"> <a class="accordion-close" href="javascript:void(0);">COLLAPSE</a> </div></div> </div> </div> </div> </li> <li class="item"> <div class="toggle-header" tabindex="-1"> <div class="label"> <div class="component content max-width pl-0"> <div class="component-content"> <div class="field-heading"><div class="bor-left"> <h3>I missed a dose. What should I do?</h3> </div></div> </div> </div> </div> </div> <div class="toggle-content"> <div class="component content max-width"> <div class="component-content"> <div class="field-content"><p>Call your doctor to find out when you should take your next dose. It’s important to take ENBREL as scheduled.</p> <div class="accordion-collapse"> <a class="accordion-close" href="javascript:void(0);">COLLAPSE</a> </div></div> </div> </div> </div> </li> <li class="item"> <div class="toggle-header" tabindex="-1"> <div class="label"> <div class="component content max-width pl-0"> <div class="component-content"> <div class="field-heading"><div class="bor-left"> <h3>How do I inject ENBREL, and who can I contact if I have questions regarding my injection?</h3> </div></div> </div> </div> </div> </div> <div class="toggle-content"> <div class="component content max-width"> <div class="component-content"> <div class="field-content"><p>Your doctor or nurse will train you on how to inject ENBREL. Remember to thoroughly review the Instructions for Use for any device that comes with your ENBREL medication you plan to use before injecting with ENBREL. Those instructions cover everything you need to know about how to use ENBREL. You can also watch the injection demonstration videos above to supplement the information you get from your doctor or nurse.</p> <p>For one-on-one supplemental injection support, Amgen Nurse Partners* can help you get more comfortable injecting on your own. They offer support when it’s most convenient for you: via video chat or over the phone. <a href="/support#enrollment">Click here</a> to enroll in the Amgen<sup>®</sup> Nurse Partner program. You can call 1-888-4ENBREL (1-888-436-2735) Monday - Friday, 8AM - 8PM ET, when you’re ready to speak with an Amgen Nurse Partner. </p> <div class="footnote"><p class="text-indent">*Amgen Nurse Partners are only available to patients that are prescribed certain Amgen products. They are not part of your treatment team and do not provide medical advice, nursing, or case management services. Amgen Nurse Partners will not inject patients with Amgen medications. Patients should always consult their healthcare provider regarding medical decisions or treatment concerns.</p></div> <div class="accordion-collapse"> <a class="accordion-close" href="javascript:void(0);">COLLAPSE</a> </div> </div> </div> </div> </div> </li> <li class="item"> <div class="toggle-header" tabindex="-1"> <div class="label"> <div class="component content max-width pl-0"> <div class="component-content"> <div class="field-heading"><div class="bor-left"> <h3>Where on the body do I inject ENBREL?</h3> </div></div> </div> </div> </div> </div> <div class="toggle-content"> <div class="component content max-width"> <div class="component-content"> <div class="field-content"><p>You can inject ENBREL on the front of the middle thigh, or on your stomach (except for the 2-inch area around your belly button). If someone else is giving you the injection, they can do so on the outer area of your upper arm. Choose a different site each time you give yourself an injection. If you need to use the same injection site, just make sure it is not on the same spot that you used last time. Do not inject into areas where the skin is tender, bruised, red, or hard. Avoid injecting into areas with scars or stretch marks.</p> <p>Skin reactions around the injection area, such as redness, pain, swelling, itching, or bruising have happened. On average, these symptoms go away within 3 to 5 days. If you have any of these reactions and they don’t go away or they get worse, call your doctor.</p> <div class="accordion-collapse"> <a class="accordion-close" href="javascript:void(0);">COLLAPSE</a> </div></div> </div> </div> </div> </li> <li class="item"> <div class="toggle-header" tabindex="-1"> <div class="label"> <div class="component content max-width pl-0"> <div class="component-content"> <div class="field-heading"><div class="bor-left"> <h3>Can I let ENBREL warm up before injecting?</h3> </div></div> </div> </div> </div> </div> <div class="toggle-content"> <div class="component content max-width"> <div class="component-content"> <div class="field-content"><p>Injecting cold ENBREL can be uncomfortable. To help make it more comfortable, take ENBREL out of the refrigerator and wait for it to reach room temperature (which should take at least 30 minutes before injecting). <b>Do not remove</b> the white cap from the ENBREL SureClick<sup>®</sup> autoinjector until you are ready to inject. <b>Do not</b> warm it in a microwave or in hot water, and <b>do not remove</b> the needle cover while you wait. Keep these guidelines in mind:</p> <ul> <li>In general, store ENBREL in the refrigerator at 36°F to 46°F (2°C to 8°C)</li> <li>You may store the ENBREL prefilled syringe, SureClick<sup>®</sup> autoinjector, ENBREL Mini<sup>®</sup> single-dose prefilled cartridge, or the ENBREL single-dose vial at room temperature between 68°F and 77°F (20°C and 25°C) for up to 30 days</li> <li>Once ENBREL has reached room temperature, do not put it back in the refrigerator</li> <li>Throw away ENBREL that has been stored at room temperature after 30 days</li> <li>For more on how to store your ENBREL at room temperature, <a href="/taking-enbrel/faq#how-should-store-enbrel" data-click-type='promo' data-click-text='click here'>click here</a>.</li> </ul> <div class="accordion-collapse"> <a class="accordion-close" href="javascript:void(0);">COLLAPSE</a> </div></div> </div> </div> </div> </li> <li class="item"> <div class="toggle-header" tabindex="-1"> <div class="label"> <div class="component content max-width pl-0"> <div class="component-content"> <div class="field-heading"><div class="bor-left"> <h3>What if my skin around the ENBREL injection site gets red and itchy?</h3> </div></div> </div> </div> </div> </div> <div class="toggle-content"> <div class="component content max-width"> <div class="component-content"> <div class="field-content"><p>Sometimes this can happen. Some common ENBREL injection site reactions include redness, pain, swelling, itching, or bruising. However, these symptoms tend to go away within 3 to 5 days. If they don’t go away (or if they get worse), call your doctor.</p> <div class="accordion-collapse"> <a class="accordion-close" href="javascript:void(0);">COLLAPSE</a> </div></div> </div> </div> </div> </li> <li class="item"> <div class="toggle-header" tabindex="-1"> <div class="label"> <div class="component content max-width pl-0"> <div class="component-content"> <div class="field-heading"><div class="bor-left"> <h3>What should I do if the needle is bent, or the injection device is damaged?</h3> </div></div> </div> </div> </div> </div> <div class="toggle-content"> <div class="component content max-width"> <div class="component-content"> <div class="field-content"><p>If a needle or an injection device is damaged in any way, don’t try to use it or fix it. Don’t throw it away either. Call <span class="no-wrap">1-888-4ENBREL</span> <span class="no-wrap">(1-888-436-2735),</span> <span class="no-wrap">8 AM–8 PM ET,</span> Monday through Friday, and we will help you.</p> <div class="accordion-collapse"> <a class="accordion-close" href="javascript:void(0);">COLLAPSE</a> </div></div> </div> </div> </div> </li> <li class="item"> <div class="toggle-header" tabindex="-1"> <div class="label"> <div class="component content max-width pl-0"> <div class="component-content"> <div class="field-heading"><div class="bor-left"> <h3>What should I do with my needles, syringes, vials, SureClick<sup>®</sup> autoinjectors, or ENBREL Mini<sup>®</sup> single-dose prefilled <br class="desktop-only">cartridges after injecting?</h3> </div></div> </div> </div> </div> </div> <div class="toggle-content"> <div class="component content max-width"> <div class="component-content"> <div class="field-content"><p>Right after injecting, discard your needle, syringe, vials, SureClick<sup>®</sup> autoinjector, or ENBREL Mini<sup>®</sup> single-dose prefilled cartridge in a puncture-resistant sharps disposal container. You can buy one at your local pharmacy. Do not recap or reuse any of the items listed above.</p> <div class="accordion-collapse"> <a class="accordion-close" href="javascript:void(0);">COLLAPSE</a> </div></div> </div> </div> </div> </li> </ul> </div> </div> </div> </div> </div> <div id="fullIsi" class="demo-shell "> <div class="demo-shell__takeover"> <div class="quantum-isi-tray quantum-isi-tray--open"> <div class="quantum-isi-tray__trigger-wrap"> <div class="quantum-isi-tray__trigger-wrap-inner"> <button id="closesFullIsi" class="quantum-button quantum-isi-tray__trigger quantum-isi-tray__trigger--open quantum-button--small" type="button"> <span class="quantum-button__text"> Close </span> </button> </div> </div> <div class="quantum-isi-tray__inner"> <div class="quantum-isi-tray__content quantum-long-form-text"> <h3> </h3> <div class="quantum-isi-tray__content quantum-long-form-text"> <h3 style="display: none;"></h3> <div id="isi-header"> <p id="prescription-text">Prescription Enbrel<sup>®</sup> (etanercept) is taken (given) by injection.</p> <p class="quantum-h3 open-isi hide-desktop pb-0 show-desktop isi-title">IMPORTANT SAFETY INFORMATION</p> </div> <div class="quantum-isi-tray__content quantum-long-form-text"> <p class="isi-subtitle">What is the most important information I should know about ENBREL?</p> <p>ENBREL is a medicine that affects your immune system. ENBREL can lower the ability of your immune system to fight infections. Serious infections have happened in patients taking ENBREL. These infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some patients have died from these infections. Your healthcare provider should test you for TB before you take ENBREL and monitor you closely for TB before, during, and after ENBREL treatment, even if you have tested negative for TB.</p> <p>There have been some cases of unusual cancers, some resulting in death, reported in children and teenagers who started using tumor necrosis factor (TNF) blockers before 18 years of age. Also, for children, teenagers, and adults taking TNF blockers, including ENBREL, the chances of getting lymphoma or other cancers may increase. Patients with RA may be more likely to get lymphoma.</p> <div> <p class="isi-subtitle">Before starting ENBREL, tell your healthcare provider if you:</p> <ul> <li>Have any existing medical conditions</li> <li>Are taking any medicines, including herbals</li> <li>Think you have, are being treated for, have signs of, or are prone to infection. You should not start taking ENBREL if you have any kind of infection, unless your healthcare provider says it is okay</li> <li>Have any open cuts or sores</li> <li>Have diabetes, HIV, or a weak immune system</li> <li>Have TB or have been in close contact with someone who has had TB</li> <li>Were born in, lived in, or traveled to countries where there is more risk for getting TB. Ask your healthcare provider if you are not sure</li> <li>Live, have lived in, or traveled to certain parts of the country (such as, the Ohio and Mississippi River valleys, or the Southwest) where there is a greater risk for certain kinds of fungal infections, such as histoplasmosis. These infections may develop or become more severe if you take ENBREL. If you don’t know if these infections are common in the areas you’ve been to, ask your healthcare provider</li> <li>Have or have had hepatitis B</li> <li>Have or have had heart failure</li> <li>Develop symptoms such as persistent fever, bruising, bleeding, or paleness while taking ENBREL</li> <li>Use the medicine Kineret (anakinra), Orencia (abatacept), or Cytoxan (cyclophosphamide)</li> <li>Are taking anti-diabetic medicines</li> <li>Have, have had, or develop a serious nervous disorder, seizures, any numbness or tingling, or a disease that affects your nervous system such as multiple sclerosis or Guillain-Barré syndrome </li> <li>Are scheduled to have surgery</li> <li>Have recently received or are scheduled for any vaccines. All vaccines should be brought up-to-date before starting ENBREL. Patients taking ENBREL should not receive live vaccines</li> <li>Are pregnant, planning to become pregnant, or breastfeeding</li> <li>Have been around someone with chicken pox</li> </ul> </div> <div> <p class="isi-subtitle" id='enbrel-side-effects'>What are the possible side effects of ENBREL?</p> <p> ENBREL can cause serious side effects including: New <b>infections</b> or worsening of infections you already have; <b>hepatitis B</b> can become active if you already have had it; <b>nervous system problems</b>, such as multiple sclerosis, seizures, or inflammation of the nerves of the eyes; <b>blood problems</b> (some fatal); new or worsening <b>heart failure</b>; new or worsening psoriasis; <b>allergic reactions; autoimmune reactions</b>, including a lupus-like syndrome and autoimmune hepatitis. </p> <p><b>Common side effects include:</b> Injection site reactions and upper respiratory infections (sinus infections).</p> <p>In general, side effects in children were similar in frequency and type as those seen in adult patients. The types of infections reported were generally mild and similar to those usually seen in children.</p> <p>These are not all the side effects with ENBREL. Tell your healthcare provider about any side effect that bothers you or does not go away.</p> <p>If you have any questions about this information, be sure to discuss them with your healthcare provider. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit <a class="isi-link" href="https://www.fda.gov/medwatch" target="_blank">www.fda.gov/medwatch</a>, or call <span class="text-nowrap">1-800-FDA-1088.</span></p> <p>Please see <a class="isi-link" href="https://www.pi.amgen.com/united_states/enbrel/derm/enbrel_pi.pdf" target="_blank">Prescribing Information</a> and <a class="isi-link" href="https://www.pi.amgen.com/united_states/enbrel/derm/enbrel_mg.pdf" target="_blank">Medication Guide</a>.</p> </div> <div id="isi-indication"> <h3 class="quantum-h3 open-isi hide-desktop pb-0 show-desktop isi-title">INDICATIONS</h3> <p>ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with moderately to severely active rheumatoid arthritis. ENBREL can be taken with methotrexate or used alone.</p> <p>ENBREL is indicated for reducing signs and symptoms of moderately to severely active polyarticular juvenile idiopathic arthritis (pJIA) in children 2 years of age or older.</p> <p>ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in adult patients with psoriatic arthritis. ENBREL can be used with or without methotrexate.</p> <p>ENBREL is indicated for active juvenile psoriatic arthritis (JPsA) in children 2 years of age or older.</p> <p>ENBREL is indicated for reducing signs and symptoms in patients with active ankylosing spondylitis.</p> <p>ENBREL is indicated for chronic moderate to severe plaque psoriasis (PsO) in children 4 years of age or older and adults who may benefit from taking injections or pills (systemic therapy) or phototherapy (ultraviolet light).</p> </div> </div> </div> </div> </div> </div> </div> <div class="demo-shell__fixed-bottom" id="IsiBottomTray"> <div class="quantum-isi-tray quantum-isi-tray--closed"> <div class="quantum-isi-tray__trigger-wrap"> <div class="quantum-isi-tray__trigger-wrap-inner"> </div> </div> <div class="quantum-isi-tray__inner"> <div class="quantum-isi-tray__content-preview quantum-long-form-text"> <button id="opensFullIsi" class="quantum-button quantum-isi-tray__trigger quantum-isi-tray__trigger--closed quantum-button--small" type="button"> <span class="quantum-button__text"> Open </span> </button> <h5> </h5> <div id="isi-header"> <p id="prescription-text" class="desktopOnly">Prescription Enbrel<sup>®</sup> (etanercept) is taken (given) by injection.</p> <p class="quantum-h3 open-isi hide-desktop pb-0 show-desktop isi-title">IMPORTANT SAFETY INFORMATION</p> </div> <div class="quantum-isi-tray__content quantum-long-form-text"> <p class="isi-subtitle">What is the most important information I should know about ENBREL?</p> <p>ENBREL is a medicine that affects your immune system. 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