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Üre döngüsü - Vikipedi
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class="mw-list-item"><a href="/wiki/%C3%96zel:Katk%C4%B1lar%C4%B1m" title="Bu IP adresinden yapılmış değişiklikler listesi [y]" accesskey="y"><span>Katkılar</span></a></li><li id="pt-anontalk" class="mw-list-item"><a href="/wiki/%C3%96zel:MesajSayfam" title="Bu IP adresindeki düzenlemeler hakkında tartışma [n]" accesskey="n"><span>Mesaj</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> </header> </div> <div class="mw-page-container"> <div class="mw-page-container-inner"> <div class="vector-sitenotice-container"> <div id="siteNotice"><!-- CentralNotice --></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="Site"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="İçindekiler" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">İçindekiler</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">kenar çubuğuna taşı</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">gizle</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">Giriş</div> </a> </li> <li id="toc-Mitokondri_evresi" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Mitokondri_evresi"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Mitokondri evresi</span> </div> </a> <ul id="toc-Mitokondri_evresi-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Özet" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Özet"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Özet</span> </div> </a> <ul id="toc-Özet-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Kaynakça" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Kaynakça"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Kaynakça</span> </div> </a> <ul id="toc-Kaynakça-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="İçindekiler" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="İçindekiler tablosunu değiştir" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">İçindekiler tablosunu değiştir</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Üre döngüsü</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Başka bir dildeki sayfaya gidin. 40 dilde mevcut" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-40" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">40 dil</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%AF%D9%88%D8%B1%D8%A9_%D8%A7%D9%84%D9%8A%D9%88%D8%B1%D9%8A%D8%A7" title="دورة اليوريا - Arapça" lang="ar" hreflang="ar" data-title="دورة اليوريا" data-language-autonym="العربية" data-language-local-name="Arapça" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/%D0%9E%D1%80%D0%BD%D0%B8%D1%82%D0%B8%D0%BD%D0%BE%D0%B2_%D1%86%D0%B8%D0%BA%D1%8A%D0%BB" title="Орнитинов цикъл - Bulgarca" lang="bg" hreflang="bg" data-title="Орнитинов цикъл" data-language-autonym="Български" data-language-local-name="Bulgarca" class="interlanguage-link-target"><span>Български</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Ciklus_ureje" title="Ciklus ureje - Boşnakça" lang="bs" hreflang="bs" data-title="Ciklus ureje" data-language-autonym="Bosanski" data-language-local-name="Boşnakça" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Cicle_de_la_urea" title="Cicle de la urea - Katalanca" lang="ca" hreflang="ca" data-title="Cicle de la urea" data-language-autonym="Català" data-language-local-name="Katalanca" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Mo%C4%8Dovinov%C3%BD_cyklus" title="Močovinový cyklus - Çekçe" lang="cs" hreflang="cs" data-title="Močovinový cyklus" data-language-autonym="Čeština" data-language-local-name="Çekçe" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Harnstoffzyklus" title="Harnstoffzyklus - Almanca" lang="de" hreflang="de" data-title="Harnstoffzyklus" data-language-autonym="Deutsch" data-language-local-name="Almanca" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-el mw-list-item"><a href="https://el.wikipedia.org/wiki/%CE%9A%CF%8D%CE%BA%CE%BB%CE%BF%CF%82_%CF%84%CE%B7%CF%82_%CE%BF%CF%85%CF%81%CE%AF%CE%B1%CF%82" title="Κύκλος της ουρίας - Yunanca" lang="el" hreflang="el" data-title="Κύκλος της ουρίας" data-language-autonym="Ελληνικά" data-language-local-name="Yunanca" class="interlanguage-link-target"><span>Ελληνικά</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Urea_cycle" title="Urea cycle - İngilizce" lang="en" hreflang="en" data-title="Urea cycle" data-language-autonym="English" data-language-local-name="İngilizce" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-eo mw-list-item"><a href="https://eo.wikipedia.org/wiki/Urea_ciklo" title="Urea ciklo - Esperanto" lang="eo" hreflang="eo" data-title="Urea ciklo" data-language-autonym="Esperanto" data-language-local-name="Esperanto" class="interlanguage-link-target"><span>Esperanto</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Ciclo_de_la_urea" title="Ciclo de la urea - İspanyolca" lang="es" hreflang="es" data-title="Ciclo de la urea" data-language-autonym="Español" data-language-local-name="İspanyolca" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%DA%86%D8%B1%D8%AE%D9%87_%D8%A7%D9%88%D8%B1%D9%87" title="چرخه اوره - Farsça" lang="fa" hreflang="fa" data-title="چرخه اوره" data-language-autonym="فارسی" data-language-local-name="Farsça" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Ureakierto" title="Ureakierto - Fince" lang="fi" hreflang="fi" data-title="Ureakierto" data-language-autonym="Suomi" data-language-local-name="Fince" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Cycle_de_l%27ur%C3%A9e" title="Cycle de l'urée - Fransızca" lang="fr" hreflang="fr" data-title="Cycle de l'urée" data-language-autonym="Français" data-language-local-name="Fransızca" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Ciclo_da_urea" title="Ciclo da urea - Galiçyaca" lang="gl" hreflang="gl" data-title="Ciclo da urea" data-language-autonym="Galego" data-language-local-name="Galiçyaca" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%9E%D7%A2%D7%92%D7%9C_%D7%94%D7%90%D7%95%D7%A8%D7%99%D7%90%D7%94" title="מעגל האוריאה - İbranice" lang="he" hreflang="he" data-title="מעגל האוריאה" data-language-autonym="עברית" data-language-local-name="İbranice" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-hr mw-list-item"><a href="https://hr.wikipedia.org/wiki/Ciklus_ureje" title="Ciklus ureje - Hırvatça" lang="hr" hreflang="hr" data-title="Ciklus ureje" data-language-autonym="Hrvatski" data-language-local-name="Hırvatça" class="interlanguage-link-target"><span>Hrvatski</span></a></li><li class="interlanguage-link interwiki-hu mw-list-item"><a href="https://hu.wikipedia.org/wiki/Karbamidciklus" title="Karbamidciklus - Macarca" lang="hu" hreflang="hu" data-title="Karbamidciklus" data-language-autonym="Magyar" data-language-local-name="Macarca" class="interlanguage-link-target"><span>Magyar</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Ciclo_dell%27urea" title="Ciclo dell'urea - İtalyanca" lang="it" hreflang="it" data-title="Ciclo dell'urea" data-language-autonym="İtaliano" data-language-local-name="İtalyanca" class="interlanguage-link-target"><span>İtaliano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E5%B0%BF%E7%B4%A0%E5%9B%9E%E8%B7%AF" title="尿素回路 - Japonca" lang="ja" hreflang="ja" data-title="尿素回路" data-language-autonym="日本語" data-language-local-name="Japonca" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EC%9A%94%EC%86%8C_%ED%9A%8C%EB%A1%9C" title="요소 회로 - Korece" lang="ko" hreflang="ko" data-title="요소 회로" data-language-autonym="한국어" data-language-local-name="Korece" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-la mw-list-item"><a href="https://la.wikipedia.org/wiki/Cyclus_ureae" title="Cyclus ureae - Latince" lang="la" hreflang="la" data-title="Cyclus ureae" data-language-autonym="Latina" data-language-local-name="Latince" class="interlanguage-link-target"><span>Latina</span></a></li><li class="interlanguage-link interwiki-mk mw-list-item"><a href="https://mk.wikipedia.org/wiki/%D0%A6%D0%B8%D0%BA%D0%BB%D1%83%D1%81_%D0%BD%D0%B0_%D1%83%D1%80%D0%B5%D0%B0" title="Циклус на уреа - Makedonca" lang="mk" hreflang="mk" data-title="Циклус на уреа" data-language-autonym="Македонски" data-language-local-name="Makedonca" class="interlanguage-link-target"><span>Македонски</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Kitaran_urea" title="Kitaran urea - Malayca" lang="ms" hreflang="ms" data-title="Kitaran urea" data-language-autonym="Bahasa Melayu" data-language-local-name="Malayca" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Ureumcyclus" title="Ureumcyclus - Felemenkçe" lang="nl" hreflang="nl" data-title="Ureumcyclus" data-language-autonym="Nederlands" data-language-local-name="Felemenkçe" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-nn mw-list-item"><a href="https://nn.wikipedia.org/wiki/Ureasyklus" title="Ureasyklus - Norveççe Nynorsk" lang="nn" hreflang="nn" data-title="Ureasyklus" data-language-autonym="Norsk nynorsk" data-language-local-name="Norveççe Nynorsk" class="interlanguage-link-target"><span>Norsk nynorsk</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Cykl_ornitynowy" title="Cykl ornitynowy - Lehçe" lang="pl" hreflang="pl" data-title="Cykl ornitynowy" data-language-autonym="Polski" data-language-local-name="Lehçe" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Ciclo_da_ureia" title="Ciclo da ureia - Portekizce" lang="pt" hreflang="pt" data-title="Ciclo da ureia" data-language-autonym="Português" data-language-local-name="Portekizce" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Ciclul_ureei" title="Ciclul ureei - Rumence" lang="ro" hreflang="ro" data-title="Ciclul ureei" data-language-autonym="Română" data-language-local-name="Rumence" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%A6%D0%B8%D0%BA%D0%BB_%D0%BC%D0%BE%D1%87%D0%B5%D0%B2%D0%B8%D0%BD%D1%8B" title="Цикл мочевины - Rusça" lang="ru" hreflang="ru" data-title="Цикл мочевины" data-language-autonym="Русский" data-language-local-name="Rusça" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Ciklus_ureje" title="Ciklus ureje - Sırp-Hırvat Dili" lang="sh" hreflang="sh" data-title="Ciklus ureje" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="Sırp-Hırvat Dili" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-sk mw-list-item"><a href="https://sk.wikipedia.org/wiki/Mo%C4%8Dovinov%C3%BD_cyklus" title="Močovinový cyklus - Slovakça" lang="sk" hreflang="sk" data-title="Močovinový cyklus" data-language-autonym="Slovenčina" data-language-local-name="Slovakça" class="interlanguage-link-target"><span>Slovenčina</span></a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Ciklus_se%C4%8Dnine" title="Ciklus sečnine - Slovence" lang="sl" hreflang="sl" data-title="Ciklus sečnine" data-language-autonym="Slovenščina" data-language-local-name="Slovence" class="interlanguage-link-target"><span>Slovenščina</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/%D0%A6%D0%B8%D0%BA%D0%BB%D1%83%D1%81_%D1%83%D1%80%D0%B5%D1%98%D0%B5" title="Циклус уреје - Sırpça" lang="sr" hreflang="sr" data-title="Циклус уреје" data-language-autonym="Српски / srpski" data-language-local-name="Sırpça" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Ureacykeln" title="Ureacykeln - İsveççe" lang="sv" hreflang="sv" data-title="Ureacykeln" data-language-autonym="Svenska" data-language-local-name="İsveççe" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-ta mw-list-item"><a href="https://ta.wikipedia.org/wiki/%E0%AE%AF%E0%AF%82%E0%AE%B0%E0%AE%BF%E0%AE%AF%E0%AE%BE_%E0%AE%9A%E0%AF%81%E0%AE%B4%E0%AE%B1%E0%AF%8D%E0%AE%9A%E0%AE%BF" title="யூரியா சுழற்சி - Tamilce" lang="ta" hreflang="ta" data-title="யூரியா சுழற்சி" data-language-autonym="தமிழ்" data-language-local-name="Tamilce" class="interlanguage-link-target"><span>தமிழ்</span></a></li><li class="interlanguage-link interwiki-th mw-list-item"><a href="https://th.wikipedia.org/wiki/%E0%B8%A7%E0%B8%B1%E0%B8%8F%E0%B8%88%E0%B8%B1%E0%B8%81%E0%B8%A3%E0%B8%A2%E0%B8%B9%E0%B9%80%E0%B8%A3%E0%B8%B5%E0%B8%A2" title="วัฏจักรยูเรีย - Tayca" lang="th" hreflang="th" data-title="วัฏจักรยูเรีย" data-language-autonym="ไทย" data-language-local-name="Tayca" class="interlanguage-link-target"><span>ไทย</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%A6%D0%B8%D0%BA%D0%BB_%D1%81%D0%B5%D1%87%D0%BE%D0%B2%D0%B8%D0%BD%D0%B8" title="Цикл сечовини - Ukraynaca" lang="uk" hreflang="uk" data-title="Цикл сечовини" data-language-autonym="Українська" data-language-local-name="Ukraynaca" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Chu_tr%C3%ACnh_ure" title="Chu trình ure - Vietnamca" lang="vi" hreflang="vi" data-title="Chu trình ure" data-language-autonym="Tiếng Việt" data-language-local-name="Vietnamca" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-yo mw-list-item"><a href="https://yo.wikipedia.org/wiki/Urea_cycle" title="Urea cycle - Yorubaca" lang="yo" hreflang="yo" data-title="Urea cycle" data-language-autonym="Yorùbá" data-language-local-name="Yorubaca" class="interlanguage-link-target"><span>Yorùbá</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E5%B0%BF%E7%B4%A0%E5%BE%AA%E7%8E%AF" title="尿素循环 - Çince" lang="zh" hreflang="zh" data-title="尿素循环" data-language-autonym="中文" data-language-local-name="Çince" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q595994#sitelinks-wikipedia" title="Dillerarası bağlantıları değiştir" class="wbc-editpage">Bağlantıları değiştir</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Ad alanları"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul 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src="//upload.wikimedia.org/wikipedia/commons/thumb/5/51/Urea_cycle_2.png/450px-Urea_cycle_2.png" decoding="async" width="450" height="519" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/5/51/Urea_cycle_2.png 1.5x" data-file-width="623" data-file-height="718" /></a><figcaption><div style="border-width: 0px; border-bottom: 1px solid black; text-align: left;"><b>Üre döngüsü reaksiyonları</b>.</div>Şemadaki Üre döngüsünün elemanları şu şekilde renklendirilmiştir: <span style="font-weight: bold;"><span style="color: blue;">enzimler</span>, <span style="color: rgb(219,155,36);">koenzimler</span>, <span style="color: rgb(151,149,45);">substratlar</span>, <span style="color: rgb(128,0,0);">inorganik moleküller</span>, <span style="color: red;">Asp ve ondan üreye aktarılan nitrojen</span>, <span style="color: green;">NH<sub>4</sub><sup>+</sup> ve ondan üreye aktarılan nitrojen</span>, <span style="color: rgb(125,125,233);">HCO<sub>3</sub><sup>-</sup> ve ondan üreye aktarılan karbon atomu</span> </span></figcaption></figure> <p><b>Üre Döngüsü</b> karaciğerde gerçekleşir ve toksik bir madde olan amonyağın daha az toksik bir madde olan üreye çevrilmesini sağlar. Daha sonra üre kana verilerek böbreğe gönderilir, oradan da idrar ile vücuttan atılır. Mitokondri ve sitoplazma evresi olmak üzere iki evreden oluşur. </p> <div class="mw-heading mw-heading2"><h2 id="Mitokondri_evresi">Mitokondri evresi</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%C3%9Cre_d%C3%B6ng%C3%BCs%C3%BC&veaction=edit&section=1" title="Değiştirilen bölüm: Mitokondri evresi" class="mw-editsection-visualeditor"><span>değiştir</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=%C3%9Cre_d%C3%B6ng%C3%BCs%C3%BC&action=edit&section=1" title="Bölümün kaynak kodunu değiştir: Mitokondri evresi"><span>kaynağı değiştir</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Karaciğer hücrelerinin mitokondri matrikslerinde gerçekleşen bu evrede ilk olarak oksidatif deaminasyon sonucu oluşmuş olan <a href="/wiki/Amonyak" title="Amonyak">amonyak</a>,aktif karbondioksit ve 2 adet <a href="/wiki/Adenozin_trifosfat" title="Adenozin trifosfat">ATP</a> molekülüne de alarak <i>Karbomoil Fosfat Sentaz I</i> enziminin yardımıyla Karbomoil Fosfat oluşturur. Burada dikkat edilecek nokta, bu enzim N-Asetil Glutamat olmadan işlev görememektedir. </p><p>Daha sonra oluşan Karbomoil Fosfat, protein sentezinde kullanılmayan bir aminoasit olan Ornitin ile Ornitin Transkarbomoilaz enzimiyle reaksiyona girerek protein sentezine girmeyen diğer bir aminoasit olan Sitrülin'e çevrilir. Sitrülin ise sitoplazmaya taşınır. Ve bu noktada Mitokondri evresi sonlanır. </p> <div class="mw-heading mw-heading2"><h2 id="Özet"><span id=".C3.96zet"></span>Özet</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%C3%9Cre_d%C3%B6ng%C3%BCs%C3%BC&veaction=edit&section=2" title="Değiştirilen bölüm: Özet" class="mw-editsection-visualeditor"><span>değiştir</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=%C3%9Cre_d%C3%B6ng%C3%BCs%C3%BC&action=edit&section=2" title="Bölümün kaynak kodunu değiştir: Özet"><span>kaynağı değiştir</span></a><span class="mw-editsection-bracket">]</span></span></div> <ol><li>Amaç toksik amonyağın daha az toksik olan üre dönüştürülmesidir.</li> <li>Arginaz enzimi yalnızca karaciğerde bulunduğu için bu döngü karaciğerde gerçekleşir.</li> <li>Toplam 3 ATP harcanır ancak 4 yüksek enerjili fosfat bağı kopar, yani 2 ADP ve 1 AMP açığa çıkar.</li> <li>Ürede 2 azot bulunur ve bunlar oksidatif deaminasyon sonucu oluşan serbest amonyak ve transaminasyon sonucu oluşan aspartattan sağlanır.</li></ol> <div class="mw-heading mw-heading2"><h2 id="Kaynakça"><span id="Kaynak.C3.A7a"></span>Kaynakça</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%C3%9Cre_d%C3%B6ng%C3%BCs%C3%BC&veaction=edit&section=3" title="Değiştirilen bölüm: Kaynakça" class="mw-editsection-visualeditor"><span>değiştir</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=%C3%9Cre_d%C3%B6ng%C3%BCs%C3%BC&action=edit&section=3" title="Bölümün kaynak kodunu değiştir: Kaynakça"><span>kaynağı değiştir</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Lippincott Illustrated Reviews Biochemistry </p></div><!--esi <esi:include src="/esitest-fa8a495983347898/content" /> --><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">"<a dir="ltr" href="https://tr.wikipedia.org/w/index.php?title=Üre_döngüsü&oldid=30468497">https://tr.wikipedia.org/w/index.php?title=Üre_döngüsü&oldid=30468497</a>" sayfasından alınmıştır</div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/%C3%96zel:Kategoriler" title="Özel:Kategoriler">Kategori</a>: <ul><li><a href="/wiki/Kategori:Biyokimya" title="Kategori:Biyokimya">Biyokimya</a></li></ul></div></div> </div> </main> </div> <div class="mw-footer-container"> <footer id="footer" class="mw-footer" > <ul id="footer-info"> <li id="footer-info-lastmod"> Sayfa en son 12.54, 30 Ekim 2023 tarihinde değiştirildi.</li> <li id="footer-info-copyright">Metin <a rel="nofollow" class="external text" href="//creativecommons.org/licenses/by-sa/4.0/deed.tr">Creative Commons Atıf-AynıLisanslaPaylaş Lisansı</a> altındadır ve ek koşullar uygulanabilir. 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