Standard Reference Materials

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href="https://tsapps.nist.gov/srmext/certificates/documents/Current_SRM_Catalog.pdf"> <picture> <source srcset="/sites/default/files/styles/600w_x_360h/public/images/2018/12/18/shutterstock_1065596462_converted-01.png.webp?itok=1wV5q8ys 1x, /sites/default/files/styles/1200w_x_720h/public/images/2018/12/18/shutterstock_1065596462_converted-01.png.webp?itok=lpQx9O-h 2x" media="(min-width: 480px)" type="image/webp" width="600" height="360"/> <source srcset="/sites/default/files/styles/300w_x_180h/public/images/2018/12/18/shutterstock_1065596462_converted-01.png.webp?itok=6sOZDM9P 1x, /sites/default/files/styles/600w_x_360h/public/images/2018/12/18/shutterstock_1065596462_converted-01.png.webp?itok=1wV5q8ys 2x" media="(min-width: 0px)" type="image/webp" width="300" height="180"/> <img loading="eager" src="/sites/default/files/styles/600w_x_360h/public/images/2018/12/18/shutterstock_1065596462_converted-01.png.jpg?itok=1wV5q8ys" width="600" height="360" alt="coral abstract background" 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height="180"/> <img loading="eager" src="/sites/default/files/styles/600w_x_360h/public/images/2020/08/04/comment.jpg.jpg?itok=TwG8sGLq" width="600" height="360" alt="comment" typeof="foaf:Image" /> </picture> </a> </div> <div class="nist-hero__caption"> <a href="https://shop.nist.gov/"> <div class="text">Find Current SRM/RM Certificates, Reports of Investigation and Safety Data Sheets using the NIST Store鈥檚 Product Search Box</div> </a> </div> </div> </div> </div> </div> <div class="nist-content-row nist-content-row--width-normal paragraph paragraph--type--text paragraph--view-mode--default"> <div class="nist-block text-long"><div class="nist-callout"><h3><strong>SRMs are available for order at the NIST store, </strong><a href="https://shop.nist.gov"><strong>https://shop.nist.gov</strong></a><strong> </strong><br><br><span><strong>Users of a NIST SRM or RM should ensure that the certificate/report in their possession is current.  Find Current SRM/RM Certificates, Reports of Investigation, and Safety Data Sheets using the NIST Store鈥檚 Product Search Box.</strong></span></h3></div></div> </div> <div class="nist-content-row nist-content-row--width-legible paragraph paragraph--type--text paragraph--view-mode--default"> <div class="nist-block text-long"><p class="critical">Due to world events, all shipping to Russia, Belarus, and Ukraine has ceased.  As a result, the Office of Reference Materials will not be accepting or processing orders to these countries for the foreseeable future. </p></div> </div> <div class="paragraph paragraph--type--dynamic-content-list-ou paragraph--view-mode--default"> <div class="nist-block " > <h2 class="nist-block__title" > <div class="string">News and Updates</div> </h2> <div class="viewsreference"><div class="views-element-container"><div class="js-view-dom-id-33734c57eb47d2d408c3d5d0943397fceb482ee73ce8e2b3b572ff01130857f0"> <div> <article about="/news-events/news/2025/03/assuring-accuracy-metabolite-measurement-and-identification" typeof="schema:Article" class="nist-teaser" > <div class="nist-teaser__image"> <div class="entity-reference"> <a href="/news-events/news/2025/03/assuring-accuracy-metabolite-measurement-and-identification" hreflang="en"><img loading="lazy" src="/sites/default/files/styles/thumbnail/public/images/2025/03/24/IMG_4972.jpg?itok=tWTjmceI" width="100" height="69" alt="SRM 8231" typeof="foaf:Image" /> </a> </div> </div> <div class="nist-teaser__content-wrapper"> <header> <h3 class="nist-teaser__title"><a href="/news-events/news/2025/03/assuring-accuracy-metabolite-measurement-and-identification"><span property="schema:name">Assuring the Accuracy of Metabolite Measurement and Identification</span> </a></h3> <div class="nist-teaser__date"> <div class="daterange"><time datetime="2025-03-18T12:00:00Z">March 18, 2025</time> </div> </div> </header> <div class="nist-teaser__content"> <div property="schema:text" class="text-with-summary"> This reference material is intended to be used as quality assurance/quality control material for laboratory metabolomic measurements. Products of metabolism act </div> </div> </div> </article> </div> <div> <article about="/news-events/news/2025/03/nist-releases-reference-material-aid-gut-microbiome-research" typeof="schema:Article" class="nist-teaser" > <div class="nist-teaser__image"> <div class="entity-reference"> <a href="/news-events/news/2025/03/nist-releases-reference-material-aid-gut-microbiome-research" hreflang="en"><img loading="lazy" src="/sites/default/files/styles/thumbnail/public/images/2025/03/13/NIST_Microbiome_Reference_Material.jpg?itok=JbnzYRBG" width="100" height="62" alt="A white box labeled "8048 Human Fecal Material" lies open, with a tray of four plastic vials pulled out. " typeof="foaf:Image" /> </a> </div> </div> <div class="nist-teaser__content-wrapper"> <header> <h3 class="nist-teaser__title"><a href="/news-events/news/2025/03/nist-releases-reference-material-aid-gut-microbiome-research"><span property="schema:name">NIST Releases Reference Material to Aid Gut Microbiome Research</span> </a></h3> <div class="nist-teaser__date"> <div class="daterange"><time datetime="2025-03-17T12:00:00Z">March 17, 2025</time> </div> </div> </header> <div class="nist-teaser__content"> <div property="schema:text" class="text-with-summary"> Researchers hope this material will help usher in a new era of diagnostics and treatments involving the gut microbiome. </div> </div> </div> </article> </div> <div> <article about="/news-events/news/2025/03/nist-researchers-develop-material-measuring-arsenic-shellfish" typeof="schema:Article" class="nist-teaser" > <div class="nist-teaser__image"> <div class="entity-reference"> <a href="/news-events/news/2025/03/nist-researchers-develop-material-measuring-arsenic-shellfish" hreflang="en"><img loading="lazy" src="/sites/default/files/styles/thumbnail/public/images/2025/03/10/IMG_4058_square.JPG?itok=HQMEBqgq" width="100" height="100" alt="A scientist wearing protective equipment places a tray of diced geoduck clam tissue into large open machinery." typeof="foaf:Image" /> </a> </div> </div> <div class="nist-teaser__content-wrapper"> <header> <h3 class="nist-teaser__title"><a href="/news-events/news/2025/03/nist-researchers-develop-material-measuring-arsenic-shellfish"><span property="schema:name">NIST Researchers Develop Material for Measuring Arsenic in Shellfish</span> </a></h3> <div class="nist-teaser__date"> <div class="daterange"><time datetime="2025-03-13T12:00:00Z">March 13, 2025</time> </div> </div> </header> <div class="nist-teaser__content"> <div property="schema:text" class="text-with-summary"> NIST鈥檚 new standard reference material will help ensure that geoduck clams and other shellfish are safe to eat. </div> </div> </div> </article> </div> <div> <article about="/news-events/news/2025/02/srm-accuracy-electrolyte-panel-clinical-tests" typeof="schema:Article" class="nist-teaser" > <div class="nist-teaser__image"> <div class="entity-reference"> <a href="/news-events/news/2025/02/srm-accuracy-electrolyte-panel-clinical-tests" hreflang="en"><img loading="lazy" src="/sites/default/files/styles/thumbnail/public/images/2025/02/26/956e.jpg?itok=RIqdFnGT" width="100" height="74" alt="Picture of 956e packaging" typeof="foaf:Image" /> </a> </div> </div> <div class="nist-teaser__content-wrapper"> <header> <h3 class="nist-teaser__title"><a href="/news-events/news/2025/02/srm-accuracy-electrolyte-panel-clinical-tests"><span property="schema:name">An SRM for Accuracy in Electrolyte Panel Clinical Tests</span> </a></h3> <div class="nist-teaser__date"> <div class="daterange"><time datetime="2025-02-26T12:00:00Z">February 26, 2025</time> </div> </div> </header> <div class="nist-teaser__content"> <div property="schema:text" class="text-with-summary"> Electrolytes are essential biomarkers for skeletal and cellular health. Abnormal levels of electrolytes may either be the cause or the consequence of various </div> </div> </div> </article> </div> <footer> <div class="link-list"><a href="/news-events/news-updates/org/5921">View All News and Updates</a></div> </footer> </div> </div> </div> </div> </div> <div class="paragraph paragraph--type--dynamic-content-list-ou paragraph--view-mode--default"> <div class="nist-block " > <h2 class="nist-block__title" > <div class="string">Projects and Programs</div> </h2> <div class="viewsreference"><div class="views-element-container"><div class="js-view-dom-id-cb538598947d15139cbeb372e21ef6ac3f7514623f092f43383265350769f635"> <div> <article about="/programs-projects/nist-her2-genomic-dna-standard-reference-material-srmr-2373" class="nist-teaser" > <div class="nist-teaser__image"> <div class="entity-reference"> <a href="/programs-projects/nist-her2-genomic-dna-standard-reference-material-srmr-2373" hreflang="en"><img loading="lazy" src="/sites/default/files/styles/thumbnail/public/images/2024/03/22/2373.jpg?itok=AIwLPVHk" width="100" height="56" alt="HER2 SRM Unit and Individual Components" typeof="foaf:Image" /> </a> </div> </div> <div class="nist-teaser__content-wrapper"> <header> <h3 class="nist-teaser__title"><a href="/programs-projects/nist-her2-genomic-dna-standard-reference-material-srmr-2373"><span>NIST HER2 Genomic DNA Standard Reference Material, SRM庐 2373</span> </a></h3> <div class="nist-teaser__type"> <div class="nist-badge display-inline-block margin-y-1 nist-badge--blue list-string">Ongoing</div> </div> </header> <div class="nist-teaser__content"> <div class="text-with-summary"> The amplification of the gene for HER2 occurs in approximately 20 to 25% of breast cancers. The accurate measurement of this biomarker is important for the proper treatment with anti-HER2 therapeutics. Clinical laboratories are beginning to utilize accurate and sensitive diagnostic tests based on </div> </div> </div> </article> </div> <footer> <div class="link-list"><a href="/laboratories/projects-programs/org/5921">View All Projects/Programs</a></div> </footer> </div> </div> </div> </div> </div> <div class="paragraph paragraph--type--dynamic-content-list-ou paragraph--view-mode--default"> <div class="nist-block " > <h2 class="nist-block__title" > <div class="string">Press Coverage</div> </h2> <div class="viewsreference"><div class="views-element-container"><div class="js-view-dom-id-2d427d1d60392d54603432ced19d2e5d492bcc9ad9834dbb0d023226d41f913a"> <div> <article about="/press-coverage/setting-standards-stool" class="nist-teaser" > <div class="nist-teaser__content-wrapper"> <header> <h3 class="nist-teaser__title"><a href="https://www.the-scientist.com/news/setting-standards-for-stool-71597"><span>Setting Standards for Stool</span> </a></h3> <div class="nist-teaser__type"> </div> <div class="nist-teaser__date"> <div class="datetime"><time datetime="2024-01-19T12:00:00Z">January 19, 2024</time> </div> </div> </header> <div class="nist-teaser__content"> <div class="text-with-summary"> Microbiome studies have yielded hundreds of ideas for ways to detect and influence human health, but the field struggles with reproducibility... </div> </div> </div> </article> </div> <div> <article about="/press-coverage/world-depends-strange-collection-items-theyre-not-cheap" class="nist-teaser" > <div class="nist-teaser__content-wrapper"> <header> <h3 class="nist-teaser__title"><a href="https://www.youtube.com/watch?v=esQyYGezS7c"><span>The World Depends on a Strange Collection of Items. They're Not Cheap</span> </a></h3> <div class="nist-teaser__type"> <div class="string">Veritasium YouTube Channel</div> </div> <div class="nist-teaser__date"> <div class="datetime"><time datetime="2022-11-19T12:00:00Z">November 19, 2022</time> </div> </div> </header> <div class="nist-teaser__content"> <div class="text-with-summary"> Steven Choquette, Benjamin Place, and Johanna Camara talk about the world of Standard Reference Materials. </div> </div> </div> </article> </div> <div> <article about="/press-coverage/keeping-americas-standards-job-nist-0" class="nist-teaser" > <div class="nist-teaser__content-wrapper"> <header> <h3 class="nist-teaser__title"><a href="https://www.economist.com/science-and-technology/2022/08/17/keeping-up-americas-standards-is-the-job-of-nist"><span>Keeping up America鈥檚 standards is the job of NIST</span> </a></h3> <div class="nist-teaser__type"> <div class="string">The Economist</div> </div> <div class="nist-teaser__date"> <div class="datetime"><time datetime="2022-08-17T12:00:00Z">August 17, 2022</time> </div> </div> </header> <div class="nist-teaser__content"> <div class="text-with-summary"> Melissa Phillips and NIST collaborators explain why NIST reference materials are so important to industry, monitoring environmental and human health, and much </div> </div> </div> </article> </div> <div> <article about="/press-coverage/made-measure-why-we-cant-stop-quantifying-our-lives" class="nist-teaser" > <div class="nist-teaser__content-wrapper"> <header> <h3 class="nist-teaser__title"><a href="https://www.theguardian.com/news/2022/may/26/measurement-why-we-cant-stop-quantifying-our-lives"><span>Made to measure: why we can鈥檛 stop quantifying our lives</span> </a></h3> <div class="nist-teaser__type"> <div class="string">The Guardian</div> </div> <div class="nist-teaser__date"> <div class="datetime"><time datetime="2022-05-26T12:00:00Z">May 26, 2022</time> </div> </div> </header> <div class="nist-teaser__content"> <div 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