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2011 | TRON Translational Oncology Mainz | Connecting Competence

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<link href="https://web.archive.org/web/20210320060847cs_/https://tron-mainz.de/de/wp-content/gdprpatron/hts/tron-mainz.de/de/wp_content/themes/canvas/custom_css.css" rel="stylesheet" type="text/css"/> <!-- Theme version --> <meta name="generator" content="Canvas 5.9.19"/> <meta name="generator" content="WooFramework 6.2.7"/> <!-- Google Webfonts --> <link href="https://web.archive.org/web/20210320060847cs_/https://tron-mainz.de/de/wp-content/gdprpatron/hts/fonts.googleapis.com/css_family_Lato_3A100_2C147212186.css" rel="stylesheet" type="text/css"/> <meta name="generator" content="Powered by WPBakery Page Builder - drag and drop page builder for WordPress."/> <style type="text/css" id="woo-header-css"> #logo .site-title a { color: #ffffff; } </style> <style> @media only screen and ( min-width: 768px ) { #nav-container { -moz-box-shadow: 0px 0px 0px #515151 !important; -webkit-box-shadow: 0px 0px 0px #515151 !important; box-shadow: 0px 0px 0px #515151 !important; } 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.primary-nav-container ul.nav { display: inline-block; vertical-align: middle; } #navigation > section > .side-nav { height:100%; vertical-align: middle; float:right; } #nav-container, #navigation { background-color: #ffffff !important; } #nav-container {border: none !important;}#nav-container { -moz-border-radius: 3px !important; -webkit-border-radius: 3px !important; border-radius: 3px !important; } #navigation ul.nav li ul { width:168px; font-size:14px; }#navigation ul.nav li { line-height:1.2em; }#navigation ul .sub-menu > li:first-child, #navigation ul .sub-menu > li:first-child > a { border-radius: 0 !important; -moz-border-radius: 0 !important; -webkit-border-radius: 0 !important; } #navigation { margin-top:0;margin-bottom:0; } #nav-container { margin-top: px; margin-bottom: px; } #navigation ul.nav > li > a { } #navigation ul.nav > li > a > i { margin-right: 5px; line-height: inherit; vertical-align: middle; color: ; } #navigation ul.nav > li > a:hover > i { color: ; } 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top: 100%; display: block; } #navigation > section { height: auto; }#navigation .side-nav > .rss { position: relative; line-height: 100%; height: 100%; } #navigation .side-nav > .rss > li { line-height: 100%; height: 100%; } #navigation .side-nav > .rss > li > a { padding-top: 0; padding-bottom: 0; line-height: 100%; height: 100%; position: relative; overflow:hidden; } #navigation .side-nav > .rss > li > a:hover { text-decoration: none; } #navigation .side-nav > ul > li > a:before { position: absolute !important; top: 50% !important; margin-top: -0.5em !important; line-height:1; } #navigation .side-nav > .cart { line-height: 100%; height: 100% } #navigation .side-nav > .cart > li { height: 100% } #navigation .side-nav > .cart > li > .cart-contents { padding-top: 0; padding-bottom: 0; line-height: 100%; height: 100%; position: relative; } @media only screen and (min-width: 980px) { #navigation .side-nav > .cart > li { display: table; } #navigation .side-nav > .cart > li > a.cart-contents { display: table-cell; vertical-align: middle; } #navigation .side-nav > .cart > li > a.cart-contents:before { position: initial !important; } } #navigation ul.cart a.cart-contents + ul { box-sizing: content-box; } #navigation .side-nav > .nav-search { line-height: 100%; height: 100% } #navigation .side-nav > .nav-search > li { height: 100% } #navigation .side-nav > .nav-search > li > .search-contents { padding-top: 0; padding-bottom: 0; line-height: 100%; height: 100%; position: relative } #navigation .side-nav > ul > li > a:before { color: #be3026 !important; } #navigation .side-nav > ul > li > a:hover:before { color: !important; } #navigation #main-nav > .menu-item > a > span { vertical-align: middle; } .side-nav ul ul input , .side-nav ul ul :before { color: !important ; } } @media only screen and ( max-width: 767px ) { #navigation ul.nav > li > a > i { display: none; } #navigation ul.nav > li ul li > a > i { display: none } } </style> <style type="text/css">/* *** 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</li> </ul></div> <div class="side-nav"> <ul class="nav-search"> <li> <a class="search-contents" href="#"></a> <ul> <li> <div class="widget widget_search"><div class="search_main"> <form method="get" class="searchform" action="https://web.archive.org/web/20210320060847/https://tron-mainz.de/de/"> <input type="text" class="field s" name="s" value="Search..." onfocus="if (this.value == 'Search...') {this.value = '';}" onblur="if (this.value == '') {this.value = 'Search...';}"/> <button type="submit" class="fa fa-search submit" name="submit" value="Search"></button> </form> <div class="fix"></div> </div></div> </li> </ul> </li> </ul> </div><!-- /#side-nav --> </section><!-- /.menus --> <a href="#top" class="nav-close"> <i class="fa fa-times"></i> <span>Return to Content</span> </a> </nav> </div><!--/#nav-container--> </header> </div><!--/#header-container--> <!-- #content Starts --> <div id="content" class="col-full"> <div id="main-sidebar-container"> <!-- #main Starts --> <section id="main"> <article class="post-6813 page type-page status-publish hentry category-publications"> <header> <h1 class="title entry-title">2011</h1> </header> <section class="entry"> <div class="vc_row wpb_row vc_row-fluid vc_column-gap-15 mpc-row"><div class="wpb_column vc_column_container vc_col-sm-9 mpc-column" data-column-id="mpc_column-416055916f50224"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element "> <div class="wpb_wrapper"> <p>Fox BA, Schendel DJ, Butterfield LH, Aamdal S, Allison JP, Ascierto P, Atkins MB, Bartunkova J, Bergmann L, Berinstein N, Bonorino CC, Borden E, Bramson JL, Britten CM, Cao X, Carson WE, Chang AE, Characiejus D, Choudhury AR, Coukos G, Gruijl T de, Dillman RO, Dolstra H, Dranoff G, Durrant LG, Finke JH, Galon J, Gollob JA, Gouttefangeas C, Grizzi F<i> et al.</i>: <b>Defining the critical hurdles in cancer immunotherapy</b>. <i>J Transl Med</i> 2011, <b>9</b>:214.<a title="DOI; Fox B.A.. et al. (2011)" href="https://web.archive.org/web/20210320060847/http://dx.doi.org/10.1186/1479-5876-9-214" target="_blank"><br> DOI</a>; <a title="Fox et al, 2011 - PubMed ID: 22168571" href="https://web.archive.org/web/20210320060847/http://www.ncbi.nlm.nih.gov/pubmed?term=22168571" target="_blank">PubMed</a></p> <p>van der Burg, S. H., Kalos M, Gouttefangeas C, Janetzki S, Ottensmeier C, Welters, M. J. P., Romero P, Britten CM, Hoos A: <strong>Harmonization of Immune Biomarker Assays for Clinical Studies</strong>. <em>Science Translational Medicine</em> 2011, <strong>3</strong>:108ps44.<br> <a href="https://web.archive.org/web/20210320060847/http://dx.doi.org/10.1126/scitranslmed.3002785" target="_blank">DOI</a>; <a title="PubMed ID: 20958924" href="https://web.archive.org/web/20210320060847/http://www.ncbi.nlm.nih.gov/pubmed/22072636" target="_blank">PubMed</a></p> <p>Moodie Z, Price L, Janetzki S, Britten CM: <strong>Response determination criteria for ELISPOT: toward a standard that can be applied across laboratories</strong>. <em>Methods in molecular biology (Clifton, N.J.)</em> 2012, <strong>792</strong>:185-196.<br> <a href="https://web.archive.org/web/20210320060847/http://dx.doi.org/10.1007/978-1-61779-325-7_15" target="_blank">DOI</a>; <a title="PubMed ID: 22345621" href="https://web.archive.org/web/20210320060847/http://www.ncbi.nlm.nih.gov/pubmed?term=21956511" target="_blank">PubMed</a></p> <p>Hobohm K, Seppmann T, Britten CM, Hoff H: <strong>Ninth annual meeting of the Association for Cancer Immunotherapy (CIMT 2011), May 25-27, 2011, Mainz, Germany</strong>. <em>Cancer immunology, immunotherapy: CII</em> 2012, <strong>61</strong>:137-143.<br> <a href="https://web.archive.org/web/20210320060847/http://dx.doi.org/10.1007/s00262-011-1131-2" target="_blank">DOI</a>; <a title="PubMed ID: 22345621" href="https://web.archive.org/web/20210320060847/http://www.ncbi.nlm.nih.gov/pubmed?term=22048716" target="_blank">PubMed</a></p> <p>Hoos A, Britten CM, Huber C, O&rsquo;Donnell-Tormey J: <b>A methodological framework to enhance the clinical success of cancer immunotherapy</b>. <i>Nat Biotechnol</i> 2011, <b>29</b>:867-870.<br> <a title="DOI; Hoos A. et al. (2011)" href="https://web.archive.org/web/20210320060847/http://dx.doi.org/10.1038/nbt.2000" target="_blank">DOI</a>; <a title="PubMed ID: 21997622" href="https://web.archive.org/web/20210320060847/http://www.ncbi.nlm.nih.gov/pubmed/21997622" target="_blank">PubMed</a></p> <p>Kreiter S, Diken M, Selmi A, Diekmann J, Attig S, H&uuml;semann Y, Koslowski M, Huber C, T&uuml;reci &Ouml;, Sahin U: <strong>FLT3 ligand enhances the cancer therapeutic potency of naked RNA vaccines</strong>. <em>Cancer research</em> 2011, <strong>71</strong>:6132-6142.<br> <a href="https://web.archive.org/web/20210320060847/http://dx.doi.org/10.1158/0008-5472.CAN-11-0291" target="_blank">DOI</a>; <a title="PubMed ID: 20958924" href="https://web.archive.org/web/20210320060847/http://www.ncbi.nlm.nih.gov/pubmed/21816907" target="_blank">PubMed</a></p> <p>Kreiter, S., Diken, M., Selmi, A., Diekmann, J., Attig, S., Husemann, Y., Koslowski, M., Huber, C., T&uuml;reci, &Ouml;., and Sahin, U. (2011). <strong>FLT3 ligand Enhances the Cancer Therapeutic Potency of Naked RNA Vaccines.</strong> Cancer Res. 2011 Oct 1;71(19):6132-42.<a title="DOI - Kreiter et al., 2011" href="https://web.archive.org/web/20210320060847/http://dx.doi.org/10.1158/0008-5472.CAN-11-0291" target="_blank"><br> DOI</a>; <a title="PubMed ID: 21816907" href="https://web.archive.org/web/20210320060847/http://www.ncbi.nlm.nih.gov/pubmed/21816907" target="_blank">PubMed</a></p> <p>Bedognetti D, Balwit JM, Wang E, Disis ML, Britten CM, Delogu LG, Tomei S, Fox BA, Gajewski TF, Marincola FM, Butterfield LH: <strong>SITC/iSBTc Cancer Immunotherapy Biomarkers Resource Document: Online resources and useful tools &ndash; a compass in the land of biomarker discovery</strong>. <em>J Transl Med</em> 2011, <strong>9</strong>:155.<br> <a href="https://web.archive.org/web/20210320060847/http://dx.doi.org/10.1186/1479-5876-9-155" target="_blank">DOI</a>; <a title="PubMed ID: 20958924" href="https://web.archive.org/web/20210320060847/http://www.ncbi.nlm.nih.gov/pubmed/21929757" target="_blank">PubMed</a></p> <p>Renard BY, L&ouml;wer M, K&uuml;hne Y, Reimer U, Rothermel A, T&uuml;reci O, Castle JC, Sahin U: <strong>rapmad: Robust analysis of peptide microarray data</strong>. <em>BMC bioinformatics</em> 2011, <strong>12</strong>:324.<a title="DOI - Renard et al., 2011" href="https://web.archive.org/web/20210320060847/http://dx.doi.org/10.1186/1471-2105-12-324" target="_blank"><br> DOI</a>; <a title="PubMed ID: 21816082" href="https://web.archive.org/web/20210320060847/http://www.ncbi.nlm.nih.gov/pubmed/21816082" target="_blank">PubMed</a></p> <p>Castle JC: <b>SNPs occur in regions with less genomic sequence conservation</b>. <i>PloS one</i> 2011, <b>6</b>:e20660.<a title="DOI - Castle et al, 2011" href="https://web.archive.org/web/20210320060847/http://dx.doi.org/10.1371/journal.pone.0020660" target="_blank"><br> DOI</a>; <a title="PubMed ID: 21674007" href="https://web.archive.org/web/20210320060847/http://www.ncbi.nlm.nih.gov/pubmed/21674007" target="_blank">PubMed</a></p> <p>T&uuml;reci O, Koslowski M, Helftenbein G, Castle J, Rohde C, Dhaene K, Seitz G, Sahin U: <strong>Claudin-18 gene structure, regulation, and expression is evolutionary conserved in mammals</strong>. <em>Gene</em> 2011, <strong>481</strong>:83-92.<a title="DOI - T眉reci et al., 2011" href="https://web.archive.org/web/20210320060847/http://dx.doi.org/10.1016/j.gene.2011.04.007" target="_blank"><br> DOI</a>; <a title="PubMed ID: 21571049" href="https://web.archive.org/web/20210320060847/http://www.ncbi.nlm.nih.gov/pubmed/21571049" target="_blank">PubMed</a></p> <p>Attig S, Price L, Janetzki S, Kalos M, Pride M, McNeil L, Clay T, Yuan J, Odunsi K, Hoos A, Romero P, Britten CM: <strong>A critical assessment for the value of markers to gate-out undesired events in HLA-peptide multimer staining protocols</strong>. <em>Journal of translational medicine</em> 2011, <strong>9</strong>:108.<br> <a href="https://web.archive.org/web/20210320060847/http://dx.doi.org/10.1186/1479-5876-9-108" target="_blank">DOI</a>; <a title="PubMed ID: 20958924" href="https://web.archive.org/web/20210320060847/http://www.ncbi.nlm.nih.gov/pubmed/21745365" target="_blank">PubMed</a></p> <p>Kreiter S, Diken M, Selmi A, T&uuml;reci &Ouml;, Sahin U: <strong>Tumor vaccination using messenger RNA: prospects of a future therapy</strong>. <em>Current opinion in immunology</em> 2011, <strong>23</strong>:399-406.<a title="DOI - Kreiter et al., 2011" href="https://web.archive.org/web/20210320060847/http://dx.doi.org/10.1016/j.coi.2011.03.007" target="_blank"><br> DOI</a>; <a title="PubMed ID: 21497074" href="https://web.archive.org/web/20210320060847/http://www.ncbi.nlm.nih.gov/pubmed/21497074" target="_blank">PubMed</a></p> <p>Schneider S, Carra G, Sahin U, Hoy B, Rieder G, Wessler S: <strong>Complex cellular responses of Helicobacter pylori-colonized gastric adenocarcinoma cells</strong>. <em>Infection and immunity</em> 2011, <strong>79</strong>:2362-2371.<br> <a href="https://web.archive.org/web/20210320060847/http://dx.doi.org/10.1128/IAI.01350-10" target="_blank">DOI</a>; <a title="PubMed ID: 20958924" href="https://web.archive.org/web/20210320060847/http://www.ncbi.nlm.nih.gov/pubmed/21402757" target="_blank">PubMed</a></p> <p>Butterfield LH, Palucka AK, Britten CM, Dhodapkar MV, Hakansson L, Janetzki S, Kawakami Y, Kleen T, Lee PP, Maccalli C, Maecker HT, Maino VC, Maio M, Malyguine A, Masucci G, Pawelec G, Potter DM, Rivoltini L, Salazar LG, Schendel DJ, Slingluff CL, Song W, Stroncek DF, Tahara H, Thurin M, Trinchieri G, van der Burg, S. H., Whiteside TL, Wigginton JM, Marincola F<em> et al.</em>: <strong>Recommendations from the iSBTc-SITC/FDA/NCI Workshop on Immunotherapy Biomarkers</strong>. <em>Clinical Cancer Research</em> 2011, <strong>17</strong>:3064-3076.<br> <a href="https://web.archive.org/web/20210320060847/http://dx.doi.org/10.1158/1078-0432.CCR-10-2234" target="_blank">DOI</a>; <a title="PubMed ID: 20958924" href="https://web.archive.org/web/20210320060847/http://www.ncbi.nlm.nih.gov/pubmed/21558394" target="_blank">PubMed</a></p> <p>Diken, M., Kreiter, S., Selmi, A., Britten, C.M., Huber, C., T&uuml;reci, &Ouml;., and Sahin, U. (2011). <strong>Selective uptake of naked vaccine RNA by dendritic cells is driven by macropinocytosis and abrogated upon DC maturation.</strong> Gene Ther. 2011 Jul;18(7):702-8.<a title="DOI - Diken et al., 2011" href="https://web.archive.org/web/20210320060847/http://dx.doi.org/10.1038/gt.2011.17" target="_blank"><br> DOI</a>; <a title="PubMed ID: 21368901" href="https://web.archive.org/web/20210320060847/http://www.ncbi.nlm.nih.gov/pubmed/21368901" target="_blank">PubMed</a></p> <p>Klamp T, Schumacher J, Huber G, K&uuml;hne C, Meissner U, Selmi A, Hiller T, Kreiter S, Markl J, T&uuml;reci &Ouml;, Sahin U: <strong>Highly specific auto-antibodies against claudin-18 isoform 2 induced by a chimeric HBcAg virus-like particle vaccine kill tumor cells and inhibit the growth of lung metastases</strong>. <em>Cancer research</em> 2011, <strong>71</strong>:516-527.<a title="DOI - Klamp et al., 2011" href="https://web.archive.org/web/20210320060847/http://dx.doi.org/10.1158/0008-5472.CAN-10-2292" target="_blank"><br> DOI</a>; <a title="PubMed ID: 21224362" href="https://web.archive.org/web/20210320060847/http://www.ncbi.nlm.nih.gov/pubmed/21224362" target="_blank">PubMed</a></p> <p>Kuhn AN, Diken M, Kreiter S, Vallazza B, T&uuml;reci &Ouml;, Sahin U: <strong>Determinants of intracellular RNA pharmacokinetics: Implications for RNA-based immunotherapeutics</strong>. <em>RNA biology</em> 2011, <strong>8</strong>:35-43.<a title="DOI - Kuhn et al., 2011" href="https://web.archive.org/web/20210320060847/http://dx.doi.org/10.4161/rna.8.1.13767" target="_blank"><br> DOI</a>; <a title="PubMed ID: 21289486" href="https://web.archive.org/web/20210320060847/http://www.ncbi.nlm.nih.gov/pubmed/21289486" target="_blank">PubMed</a></p> </div> </div> </div></div></div><div class="wpb_column vc_column_container vc_col-sm-3 mpc-column"><div class="vc_column-inner"><div class="wpb_wrapper"> <div 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