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"https://www.academia.edu/login?post_login_redirect_url=https%3A%2F%2Fwww.academia.edu%2F73781090%2FBacterial_etiology_of_acute_otitis_media_in_the_era_prior_to_universal_pneumococcal_vaccination_in_Taiwanese_children%3Fshow_translation%3Dtrue"; window.loswp.previewableAttachments = [{"id":82168706,"identifier":"Attachment_82168706","shouldShowBulkDownload":false}]; window.loswp.shouldDetectTimezone = true; window.loswp.shouldShowBulkDownload = true; window.loswp.showSignupCaptcha = false window.loswp.willEdgeCache = false; window.loswp.work = {"work":{"id":73781090,"created_at":"2022-03-14T19:11:39.808-07:00","from_world_paper_id":198553524,"updated_at":"2024-11-24T08:58:31.099-08:00","_data":{"publisher":"Elsevier BV","grobid_abstract":"Background: Acute otitis media (AOM) is one of the most frequent bacterial infections in children. Streptococcus pneumoniae and nontypeable Haemophilus influenzae (NTHi) are the two major bacterial pathogens. Pneumococcal conjugate vaccine was introduced into Taiwan in 2005 and only some children were vaccinated. This retrospective study assessed the bacterial etiology of AOM and its antimicrobial susceptibility in the era prior to universal pneumococcal vaccination in Taiwan. Methods: From December 2009 to November 2011, children presenting with AOM and having a middle ear effusion sample collected by tympanocentesis were enrolled. The study period was divided into two parts. Demographic data of patients and antibiotic susceptibility of the pathogens were collected and analyzed. Serotypes of S. pneumoniae were identified. Results: Among the 151 episodes, 46% of samples found bacterial pathogens. S. pneumoniae and NTHi were the leading causes of AOM, detected in 55.7% and 22.9% of bacterial AOM episodes, respectively. The prevalent serotypes of S. pneumoniae were 19 A and 19 F.","publication_date":"2013,,","publication_name":"Journal of Microbiology, Immunology and Infection","grobid_abstract_attachment_id":"82168706"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Bacterial etiology of acute otitis media in the era prior to universal pneumococcal vaccination in Taiwanese children","broadcastable":false,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [217595099]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div 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translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Bacterial etiology of acute otitis media in the era prior to universal pneumococcal vaccination in Taiwanese children</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="217595099" href="https://independent.academia.edu/YuChiaHsieh"><img alt="Profile image of Yu Chia Hsieh" class="ds-work-card--author-avatar" src="https://0.academia-photos.com/217595099/75880162/64396932/s65_yu_chia.hsieh.jpeg" />Yu Chia Hsieh</a></div><p class="ds-work-card--detail ds2-5-body-sm">2013, Journal of Microbiology, Immunology and Infection</p><div class="ds-work-card--button-container"><button class="ds2-5-button 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data-landing_url="https://www.academia.edu/73781090/Bacterial_etiology_of_acute_otitis_media_in_the_era_prior_to_universal_pneumococcal_vaccination_in_Taiwanese_children" data-login_uri="https://www.academia.edu/registrations/google_one_tap" data-moment_callback="onGoogleOneTapEvent" id="g_id_onload"></div><div class="ds-top-related-works--grid-container"><div class="ds-related-content--container ds-top-related-works--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="0" data-entity-id="122176306" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/122176306/Bacterial_Etiology_and_Pneumococcal_Serotypes_in_Turkish_Children_with_Acute_Otitis_Media">Bacterial Etiology and Pneumococcal Serotypes in Turkish Children with Acute Otitis Media</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="158709780" href="https://independent.academia.edu/NezahatG%C3%BCrler">Nezahat Gürler</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Vaccines & Vaccination, 2014</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Bacterial Etiology and Pneumococcal Serotypes in Turkish Children with Acute Otitis Media","attachmentId":116894661,"attachmentType":"pdf","work_url":"https://www.academia.edu/122176306/Bacterial_Etiology_and_Pneumococcal_Serotypes_in_Turkish_Children_with_Acute_Otitis_Media","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/122176306/Bacterial_Etiology_and_Pneumococcal_Serotypes_in_Turkish_Children_with_Acute_Otitis_Media"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="1" data-entity-id="56544127" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/56544127/Etiology_of_acute_otitis_media_and_serotype_distribution_of_Streptococcus_pneumoniae_and_Haemophilus_influenzae_in_Chilean_children_5_years_of_age">Etiology of acute otitis media and serotype distribution of Streptococcus pneumoniae and Haemophilus influenzae in Chilean children <5 years of age</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="70241540" href="https://independent.academia.edu/CarlaNapolitano">Carla Napolitano</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Medicine, 2017</p><p class="ds-related-work--abstract ds2-5-body-sm">The impact of bacterial conjugate vaccines on acute otitis media (AOM) is affected by several factors including population characteristics, bacterial etiology and vaccine conjugation method, carrier, and coverage. This study estimated the baseline etiology, distribution, and antibiotic susceptibility of bacterial serotypes that causes AOM in children aged &lt;5 years in a public setting in Santiago, Chile.Children aged ≥3 months and &lt;5 years referred to the physician for treatment of AOM episodes (with an onset of symptoms &lt;72 h) were enrolled between September 2009 and September 2010. Middle ear fluid (MEF) was collected by tympanocentesis or by otorrhea for identification and serotyping of bacteria. Antibacterial susceptibility was tested using E-test (etrack: 112671).Of 160 children (mean age 27.10 ± 15.83 months) with AOM episodes, 164 MEF samples (1 episode each from 156 children; 2 episodes each from 4 children) were collected. Nearly 30% of AOM episodes occurred in chil...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Etiology of acute otitis media and serotype distribution of Streptococcus pneumoniae and Haemophilus influenzae in Chilean children \u003c5 years of age","attachmentId":71879917,"attachmentType":"pdf","work_url":"https://www.academia.edu/56544127/Etiology_of_acute_otitis_media_and_serotype_distribution_of_Streptococcus_pneumoniae_and_Haemophilus_influenzae_in_Chilean_children_5_years_of_age","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/56544127/Etiology_of_acute_otitis_media_and_serotype_distribution_of_Streptococcus_pneumoniae_and_Haemophilus_influenzae_in_Chilean_children_5_years_of_age"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="16546853" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/16546853/Microbiological_characterization_of_Streptococcus_pneumoniae_and_non_typeable_Haemophilus_influenzae_isolates_as_primary_causes_of_acute_otitis_media_in_Bulgarian_children_before_the_introduction_of_conjugate_vaccines">Microbiological characterization of Streptococcus pneumoniae and non-typeable Haemophilus influenzae isolates as primary causes of acute otitis media in Bulgarian children before the introduction of conjugate vaccines</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="35976275" href="https://independent.academia.edu/AlexandraAlexandrova3">Alexandra Alexandrova</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="36127066" href="https://independent.academia.edu/DimitarNashev">Dimitar Nashev</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="35828355" href="https://independent.academia.edu/TKostyanev">T. Kostyanev</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="37781746" href="https://independent.academia.edu/LenaSetchanova">Lena Setchanova</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Annals of Clinical Microbiology and Antimicrobials, 2013</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Microbiological characterization of Streptococcus pneumoniae and non-typeable Haemophilus influenzae isolates as primary causes of acute otitis media in Bulgarian children before the introduction of conjugate vaccines","attachmentId":42441845,"attachmentType":"pdf","work_url":"https://www.academia.edu/16546853/Microbiological_characterization_of_Streptococcus_pneumoniae_and_non_typeable_Haemophilus_influenzae_isolates_as_primary_causes_of_acute_otitis_media_in_Bulgarian_children_before_the_introduction_of_conjugate_vaccines","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/16546853/Microbiological_characterization_of_Streptococcus_pneumoniae_and_non_typeable_Haemophilus_influenzae_isolates_as_primary_causes_of_acute_otitis_media_in_Bulgarian_children_before_the_introduction_of_conjugate_vaccines"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="3" data-entity-id="78628895" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/78628895/Streptococcus_pneumoniae_serotypes_carried_by_young_children_and_their_association_with_Acute_Otitis_Media_during_the_period_2016_2019">Streptococcus pneumoniae serotypes carried by young children and their association with Acute Otitis Media during the period 2016 – 2019</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="96104715" href="https://independent.academia.edu/EsraEkinci3">Esra Ekinci</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2020</p><p class="ds-related-work--abstract ds2-5-body-sm">BackgroundStreptococcus pneumoniae (Sp) is a major cause of acute otitis media (AOM). Pneumococcal conjugate vaccine (PCV) programs have altered pneumococcal serotype epidemiology in disease and carriage. To establish the clinical picture of AOM in young children exposed to the PCV program in Belgium and the Sp strains they carry, a cross-sectional study started in 2016.Material/methodsIn three collection periods from February 2016 to May 2018, nasopharyngeal swabs and background characteristics were collected from children aged 6-30 months either presenting at their physician with AOM (AOM-group) or healthy and attending day care (DCC-group). Sp was detected, quantified, and characterized using both conventional culture and qPCR. Clinical signs of AOM episodes and treatment were registered by the physicians.ResultsAmong 3264 collected samples, overall pneumococcal carriage and density were similar in AOM (79.2% and 0.50 ×106 copies/μl) and DCC (77.5% and 0.42 ×106 copies/μl). Non-v...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Streptococcus pneumoniae serotypes carried by young children and their association with Acute Otitis Media during the period 2016 – 2019","attachmentId":85611841,"attachmentType":"pdf","work_url":"https://www.academia.edu/78628895/Streptococcus_pneumoniae_serotypes_carried_by_young_children_and_their_association_with_Acute_Otitis_Media_during_the_period_2016_2019","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/78628895/Streptococcus_pneumoniae_serotypes_carried_by_young_children_and_their_association_with_Acute_Otitis_Media_during_the_period_2016_2019"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="108008291" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/108008291/Non_typeable_Haemophilus_influenzae_and_Streptococcus_pneumoniaeas_primary_causes_of_acute_otitis_media_in_colombian_children_a_prospective_study">Non-typeable Haemophilus influenzae and Streptococcus pneumoniaeas primary causes of acute otitis media in colombian children: a prospective study</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="272450858" href="https://independent.academia.edu/anamilenaortizsierra">ana milena ortiz sierra</a></div><p class="ds-related-work--metadata ds2-5-body-xs">BMC Infectious Diseases, 2011</p><p class="ds-related-work--abstract ds2-5-body-sm">BackgroundAcute otitis media (AOM) is one of the most frequently encountered bacterial infections in children aged &lt; 5 years;Streptococcus pneumoniae(S. pneumoniae) and non-typeableHaemophilus influenzae(NTHi) are historically identified as primary AOM causes. Nevertheless, recent data on bacterial pathogens causing AOM in Latin America are limited. This prospective study aimed to identify and characterize bacterial etiology and serotypes of AOM cases including antimicrobial susceptibility in &lt; 5 year old Colombian children.MethodsFrom February 2008 to January 2009, children ≥3 months and &lt; 5 years of age presenting with AOM and for whom a middle ear fluid (MEF) sample was available were enrolled in two medical centers in Cali, Colombia. MEF samples were collected either by tympanocentesis procedure or spontaneous otorrhea swab sampling. Bacteria were identified using standard laboratory methods, and antimicrobial resistance testing was performed based on the 2009 Clinical ...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Non-typeable Haemophilus influenzae and Streptococcus pneumoniaeas primary causes of acute otitis media in colombian children: a prospective study","attachmentId":106509524,"attachmentType":"pdf","work_url":"https://www.academia.edu/108008291/Non_typeable_Haemophilus_influenzae_and_Streptococcus_pneumoniaeas_primary_causes_of_acute_otitis_media_in_colombian_children_a_prospective_study","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/108008291/Non_typeable_Haemophilus_influenzae_and_Streptococcus_pneumoniaeas_primary_causes_of_acute_otitis_media_in_colombian_children_a_prospective_study"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="107801063" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/107801063/Epidemiology_and_antimicrobial_susceptibility_of_non_typeable_Haemophilus_influenzae_in_otitis_media_in_Taiwanese_children">Epidemiology and antimicrobial susceptibility of non-typeable Haemophilus influenzae in otitis media in Taiwanese children</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="32610300" href="https://independent.academia.edu/KuoshengLee">Kuo-sheng Lee</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Microbiology Immunology and Infection, 2019</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Epidemiology and antimicrobial susceptibility of non-typeable Haemophilus influenzae in otitis media in Taiwanese children","attachmentId":106364010,"attachmentType":"pdf","work_url":"https://www.academia.edu/107801063/Epidemiology_and_antimicrobial_susceptibility_of_non_typeable_Haemophilus_influenzae_in_otitis_media_in_Taiwanese_children","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/107801063/Epidemiology_and_antimicrobial_susceptibility_of_non_typeable_Haemophilus_influenzae_in_otitis_media_in_Taiwanese_children"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="68839411" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/68839411/Pneumococcal_acute_otitis_media_in_infants_and_children_in_central_Romania_2009_2011_microbiological_characteristics_and_potential_coverage_by_pneumococcal_conjugate_vaccines">Pneumococcal acute otitis media in infants and children in central Romania, 2009–2011: microbiological characteristics and potential coverage by pneumococcal conjugate vaccines</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="32346115" href="https://bgu.academia.edu/EugeneLeibovitz">Eugene Leibovitz</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Journal of Infectious Diseases, 2013</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Pneumococcal acute otitis media in infants and children in central Romania, 2009–2011: microbiological characteristics and potential coverage by pneumococcal conjugate vaccines","attachmentId":79170836,"attachmentType":"pdf","work_url":"https://www.academia.edu/68839411/Pneumococcal_acute_otitis_media_in_infants_and_children_in_central_Romania_2009_2011_microbiological_characteristics_and_potential_coverage_by_pneumococcal_conjugate_vaccines","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/68839411/Pneumococcal_acute_otitis_media_in_infants_and_children_in_central_Romania_2009_2011_microbiological_characteristics_and_potential_coverage_by_pneumococcal_conjugate_vaccines"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="24315216" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/24315216/Study_of_bacterial_etiology_of_acute_otitis_media_in_Bulgaria_before_introduction_of_pneumococcal_conjugate_vaccine">Study of bacterial etiology of acute otitis media in Bulgaria before introduction of pneumococcal conjugate vaccine</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="37781746" href="https://independent.academia.edu/LenaSetchanova">Lena Setchanova</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Problems of Infectious and Parasitic Diseases</p><p class="ds-related-work--abstract ds2-5-body-sm">We report microbiological data on 119 middle ear specimens collected from children aged S 8 years diagnosed with AOM between October 2009 and November 2010. Among culture positive samples (105/119; 88%) the most frequently isolated pathogen was S.pneumoniae (47,6%), followed by H.influenzae (27,6%), M.catarrhalis (8,6%) and S.pyogenes (6,7%). All H. influenzae isolates, except one, were non-typable (97%). The most commonly encountered serotype among pneumococcal isolates was 19F (24%), followed by 6B (14%), 14 (8%), 9V and 3 (6% each) and 23F and 18C (4% each). The prevalence of penicillin non-susceptible S. pneumoniae was relatively high (52%) and associated mainly with serotypes 19F, 6B and 14.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Study of bacterial etiology of acute otitis media in Bulgaria before introduction of pneumococcal conjugate vaccine","attachmentId":44652560,"attachmentType":"pdf","work_url":"https://www.academia.edu/24315216/Study_of_bacterial_etiology_of_acute_otitis_media_in_Bulgaria_before_introduction_of_pneumococcal_conjugate_vaccine","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/24315216/Study_of_bacterial_etiology_of_acute_otitis_media_in_Bulgaria_before_introduction_of_pneumococcal_conjugate_vaccine"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="90824600" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/90824600/Multinational_study_of_pneumococcal_serotypes_causing_acute_otitis_media_in_children">Multinational study of pneumococcal serotypes causing acute otitis media in children</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="10705651" href="https://independent.academia.edu/brianwynne">brian wynne</a></div><p class="ds-related-work--metadata ds2-5-body-xs">The Pediatric Infectious Disease Journal, 2002</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Multinational study of pneumococcal serotypes causing acute otitis media in children","attachmentId":94280662,"attachmentType":"pdf","work_url":"https://www.academia.edu/90824600/Multinational_study_of_pneumococcal_serotypes_causing_acute_otitis_media_in_children","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/90824600/Multinational_study_of_pneumococcal_serotypes_causing_acute_otitis_media_in_children"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="93818372" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/93818372/Prevalence_of_Streptococcus_Pneumonia_and_Haemophillus_Influenza_in_primary_school_children_that_diagnosed_acute_otitis_media">Prevalence of Streptococcus Pneumonia and Haemophillus Influenza in primary school children that diagnosed acute otitis media</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="21089651" href="https://independent.academia.edu/wibowoyudhi">yudhi wibowo</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2021</p><p class="ds-related-work--abstract ds2-5-body-sm">Acute otitis media (AOM) remains a disease that cause major public health problem worldwide. Less information about its prevalence in Indonesia, especially in Java.&nbsp; The most common bacterial causes of AOM are Streptococcus pneumoniae, non-typeable Haemophilus influenzae, and Moraxella catarrhalis. There is increasing evidence that the predominant causative pathogen in AOM is changing from Streptococcus pneumoniae to non-typeable Haemophilus influenza since the introduction of pneumococcal conjugate vaccines. This study aims to determine the prevalence of Streptococcus pneumonia and Haemophillus influenzae in AOM in primary school children in Banyumas Regency. The design of this study was cross sectional and we conducted multistage random sampling to recruit the subject. Approximately 3,574 school children in Urban Banyumas Regency were screened based on the diagnose of AOM by Otolaryngologist. The resultof this study showed that the prevalence of AOM was 4,64 % (166 children w...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Prevalence of Streptococcus Pneumonia and Haemophillus Influenza in primary school children that diagnosed acute otitis media","attachmentId":96450247,"attachmentType":"pdf","work_url":"https://www.academia.edu/93818372/Prevalence_of_Streptococcus_Pneumonia_and_Haemophillus_Influenza_in_primary_school_children_that_diagnosed_acute_otitis_media","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/93818372/Prevalence_of_Streptococcus_Pneumonia_and_Haemophillus_Influenza_in_primary_school_children_that_diagnosed_acute_otitis_media"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--sticky-ctas","attachmentId":82168706,"attachmentType":"pdf","workUrl":null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--sticky-ctas","attachmentId":82168706,"attachmentType":"pdf","workUrl":null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_82168706" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. 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