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(PDF) Measurement of cortisol, dehydroepiandrosterone, and testosterone in the hair of children: Preliminary results and promising indications | Julian Simmons - Academia.edu

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{"work":{"id":87293076,"created_at":"2022-09-25T16:13:18.366-07:00","from_world_paper_id":215871770,"updated_at":"2024-03-12T06:53:01.462-07:00","_data":{"publisher":"Wiley","publication_date":"2018,,","publication_name":"Developmental Psychobiology"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Measurement of cortisol, dehydroepiandrosterone, and testosterone in the hair of children: Preliminary results and promising indications","broadcastable":true,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [30691184]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" 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data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/67745438/Title_Validation_of_an_adapted_procedure_to_collect_hair_for_cortisol_determination_in_adolescents_Running_title_Adaption_of_the_collection_protocol_for_hair_cortisol_determination">Title : Validation of an adapted procedure to collect hair for cortisol determination in adolescents Running title : Adaption of the collection protocol for hair cortisol determination</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33122434" href="https://umontreal.academia.edu/IsabelleOuelletmorin">Isabelle Ouellet-morin</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2017</p><p class="ds-related-work--abstract ds2-5-body-sm">Introduction: In the last decades, cortisol has been extensively studied in association to early exposure to adversity as well as in the etiology of a number of physical and mental problems. While saliva and blood samples allow the measurement of acute changes in cortisol secretion, hair samples are thought to provide a valid retrospective measure of chronic cortisol secretion over an extended period of time. Nevertheless, the existing protocol for hair collection involves considerable financial and logistical challenges when performed in large epidemiological studies. Objective: This study aimed to validate an adapted collection protocol asking participants to sample their hair at home and to send it back to our laboratory by regular mail. Methods: Participants were 34 teenagers between 17 and 18 years of age. They participated in two hair collections: a) at home, with the help of someone they know, and b) in our laboratory, with a trained research assistant. Results: We noted a st...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Title : Validation of an adapted procedure to collect hair for cortisol determination in adolescents Running title : Adaption of the collection protocol for hair cortisol determination&quot;,&quot;attachmentId&quot;:78459656,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/67745438/Title_Validation_of_an_adapted_procedure_to_collect_hair_for_cortisol_determination_in_adolescents_Running_title_Adaption_of_the_collection_protocol_for_hair_cortisol_determination&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/67745438/Title_Validation_of_an_adapted_procedure_to_collect_hair_for_cortisol_determination_in_adolescents_Running_title_Adaption_of_the_collection_protocol_for_hair_cortisol_determination"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="23715247" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/23715247/Hair_cortisol_stress_exposure_and_mental_health_in_humans_A_systematic_review">Hair cortisol, stress exposure, and mental health in humans: A systematic review</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33049582" href="https://independent.academia.edu/ElisabethVanRossum">Elisabeth Van Rossum</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Psychoneuroendocrinology, 2013</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Hair cortisol, stress exposure, and mental health in humans: A systematic review&quot;,&quot;attachmentId&quot;:44137807,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/23715247/Hair_cortisol_stress_exposure_and_mental_health_in_humans_A_systematic_review&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/23715247/Hair_cortisol_stress_exposure_and_mental_health_in_humans_A_systematic_review"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="23715261" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/23715261/Clinical_applications_of_cortisol_measurements_in_hair">Clinical applications of cortisol measurements in hair</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33049582" href="https://independent.academia.edu/ElisabethVanRossum">Elisabeth Van Rossum</a></div><p class="ds-related-work--metadata ds2-5-body-xs">European journal of endocrinology / European Federation of Endocrine Societies, 2015</p><p class="ds-related-work--abstract ds2-5-body-sm">Cortisol measurements in blood, saliva, and urine are frequently used to examine the hypothalamus-pituitary-adrenal axis in clinical practice and in research. However, cortisol levels are subject to variations due to acute stress, the diurnal rhythm and pulsatile secretion. Cortisol measurements in body fluids are not always a reflection of long-term cortisol exposure. The analysis of cortisol in scalp hair is a relatively novel method to measure cumulative cortisol exposure over months up to years. Over the past years, hair cortisol concentrations (HCC) have been examined in association with a large number of somatic and mental health conditions. HCC can be used to evaluate disturbances of the HPA axis, including Cushing&amp;#39;s syndrome, and to evaluate hydrocortisone treatment. Using HCC, retrospective timelines of cortisol exposure can be created, which can be of value in diagnosing cyclic hypercortisolism. HCC have also been shown to increase with psychological stressors, includi...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Clinical applications of cortisol measurements in hair&quot;,&quot;attachmentId&quot;:44137817,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/23715261/Clinical_applications_of_cortisol_measurements_in_hair&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/23715261/Clinical_applications_of_cortisol_measurements_in_hair"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="114803292" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/114803292/Psychosocial_factors_and_Cortisol_sampled_from_Hair_and_Saliva">Psychosocial factors and Cortisol sampled from Hair and Saliva</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="89556306" href="https://ucl.academia.edu/BiancaSerwinski">Bianca Serwinski</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Doctoral thesis, UCL (University College London)., 2017</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Psychosocial factors and Cortisol sampled from Hair and Saliva&quot;,&quot;attachmentId&quot;:111398581,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/114803292/Psychosocial_factors_and_Cortisol_sampled_from_Hair_and_Saliva&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/114803292/Psychosocial_factors_and_Cortisol_sampled_from_Hair_and_Saliva"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;continue-reading-button--sticky-ctas&quot;,&quot;attachmentId&quot;:91543009,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;workUrl&quot;:null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;download-pdf-button--sticky-ctas&quot;,&quot;attachmentId&quot;:91543009,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;workUrl&quot;:null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_91543009" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. 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