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(prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox ib-medical-condition"><tbody><tr><th colspan="2" class="infobox-above" style="background:#ccc">Basaloid squamous cell lung carcinoma</th></tr><tr><th scope="row" class="infobox-label"><a href="/wiki/Medical_specialty" title="Medical specialty">Specialty</a></th><td class="infobox-data">Oncology</td></tr></tbody></table> <p><b>Basaloid squamous cell carcinoma</b> (Bas-SqCC) is an uncommon <a href="/wiki/Histology" title="Histology">histological</a> variant of <a href="/wiki/Lung_cancer" title="Lung cancer">lung cancer</a> composed of cells exhibiting <a href="/wiki/Cytopathology" title="Cytopathology">cytological</a> and <a href="/wiki/Tissue_(biology)" title="Tissue (biology)">tissue</a> architectural features of both <a href="/wiki/Squamous-cell_lung_carcinoma" class="mw-redirect" title="Squamous-cell lung carcinoma">squamous cell lung carcinoma</a> and <a href="/wiki/Basal_cell_carcinoma" class="mw-redirect" title="Basal cell carcinoma">basal cell carcinoma</a>.<sup id="cite_ref-who2004_1-0" class="reference"><a href="#cite_note-who2004-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Classification">Classification</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Basaloid_squamous_cell_lung_carcinoma&action=edit&section=1" title="Edit section: Classification"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Lung cancer is a large and exceptionally <a href="/wiki/Heterogeneous" class="mw-redirect" title="Heterogeneous">heterogeneous</a> family of malignancies.<sup id="cite_ref-pmid2987102_2-0" class="reference"><a href="#cite_note-pmid2987102-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Over 50 different histological variants of lung cancer are explicitly recognized within the fourth (2004) revision of the <a href="/wiki/World_Health_Organization" title="World Health Organization">World Health Organization</a> Classification of Lung Tumours ("WHO-2004").<sup id="cite_ref-who2004_1-1" class="reference"><a href="#cite_note-who2004-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> Many of these entities are quite rare, have only been recently described, and remain poorly understood.<sup id="cite_ref-pmid11829087_3-0" class="reference"><a href="#cite_note-pmid11829087-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> </p><p>Basaloid forms of lung <a href="/wiki/Carcinoma" title="Carcinoma">carcinoma</a> were first described in the <a href="/wiki/Peer_review" title="Peer review">peer-reviewed</a> medical literature by Dr. Elisabeth Brambilla and her colleagues in 1992.<sup id="cite_ref-pmid1381335_4-0" class="reference"><a href="#cite_note-pmid1381335-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> </p><p>In the third revision of the <a href="/wiki/World_Health_Organization" title="World Health Organization">World Health Organization</a> lung tumor typing and classification scheme, published in 1999, basaloid variants of both <a href="/wiki/Squamous-cell_lung_carcinoma" class="mw-redirect" title="Squamous-cell lung carcinoma">squamous cell lung carcinoma</a> (SqCC) and <a href="/wiki/Large-cell_lung_carcinoma" title="Large-cell lung carcinoma">large cell lung carcinoma</a> (LCLC) were recognized as distinct entities.<sup id="cite_ref-pmid11829087_3-1" class="reference"><a href="#cite_note-pmid11829087-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> In the fourth revision (2004) of the WHO system (currently the world standard) Bas-SqCC is classified as one of four recognized variants of <a href="/wiki/Squamous-cell_lung_carcinoma" class="mw-redirect" title="Squamous-cell lung carcinoma">squamous cell lung carcinoma</a>.<sup id="cite_ref-who2004_1-2" class="reference"><a href="#cite_note-who2004-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> As a variant of SqCC, it is considered a <a href="/wiki/Non-small-cell_lung_cancer" title="Non-small-cell lung cancer">non-small cell lung cancer</a> (NSCLC). </p> <div class="mw-heading mw-heading2"><h2 id="Pathogenesis">Pathogenesis</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Basaloid_squamous_cell_lung_carcinoma&action=edit&section=2" title="Edit section: Pathogenesis"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Both basaloid and squamous cell carcinomas have been shown to arise from pre-malignant <a href="/wiki/Lesions" class="mw-redirect" title="Lesions">lesions</a> of <a href="/wiki/Dysplasia" title="Dysplasia">dysplasia</a> in the airways of the lung.<sup id="cite_ref-pmid19187179_5-0" class="reference"><a href="#cite_note-pmid19187179-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Diagnosis">Diagnosis</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Basaloid_squamous_cell_lung_carcinoma&action=edit&section=3" title="Edit section: Diagnosis"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Like other forms of <a href="/wiki/Lung_cancer" title="Lung cancer">lung cancer</a>, Bas-SqCC is ultimately diagnosed after a <a href="/wiki/Pathologist" class="mw-redirect" title="Pathologist">pathologist</a> examines a <a href="/wiki/Tumor" class="mw-redirect" title="Tumor">tumor</a> sample containing viable <a href="/wiki/Malignant" class="mw-redirect" title="Malignant">malignant</a> cells and tissue under a light <a href="/wiki/Microscope" title="Microscope">microscope</a> and identifies certain particular characteristics.<sup id="cite_ref-HollandFrei6_6-0" class="reference"><a href="#cite_note-HollandFrei6-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p><p>In the case of Bas-SqCC, it is essential that both evidence of <a href="/wiki/Squamous" class="mw-redirect" title="Squamous">squamous</a> differentiation (i.e., intercellular bridges, production of <a href="/wiki/Keratin" title="Keratin">keratin</a>, <a href="/wiki/Tonofilament" class="mw-redirect" title="Tonofilament">tonofilament</a> bundles) and basaloid architecture (i.e. prominent peripheral palisading of cell nuclei, organoid/lobular structures) are identified to make a correct diagnosis.<sup id="cite_ref-pmid11829087_3-2" class="reference"><a href="#cite_note-pmid11829087-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid18094005_7-0" class="reference"><a href="#cite_note-pmid18094005-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p><p>Immunohistochemical markers that have been suggested to be useful in making an accurate diagnosis of Bas-SqCC include positivity for p63 and high molecular weight <a href="/wiki/Keratin" title="Keratin">keratin</a> (i.e. 34betaE12), and lack of expression of <a href="/wiki/Thyroid_transcription_factor-1" class="mw-redirect" title="Thyroid transcription factor-1">thyroid transcription factor-1</a> (TTF-1).<sup id="cite_ref-pmid11567220_8-0" class="reference"><a href="#cite_note-pmid11567220-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid21319315_9-0" class="reference"><a href="#cite_note-pmid21319315-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid21254456_10-0" class="reference"><a href="#cite_note-pmid21254456-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </p><p>Among other pulmonary malignancies, the main differential diagnoses in suspected cases of Bas-SqCC include the high-grade <a href="/wiki/Neuroendocrine" class="mw-redirect" title="Neuroendocrine">neuroendocrine</a> carcinomas, such as <a href="/wiki/Small_cell_carcinoma" class="mw-redirect" title="Small cell carcinoma">small cell carcinoma</a> and <a href="/wiki/Large_cell_neuroendocrine_carcinoma_of_the_lung" title="Large cell neuroendocrine carcinoma of the lung">large cell neuroendocrine carcinoma</a>. The issue of differential diagnosis is particularly acute when the <a href="/wiki/Pathologist" class="mw-redirect" title="Pathologist">pathologist</a> must use a small <a href="/wiki/Biopsy" title="Biopsy">biopsy</a> specimen or <a href="/wiki/Cytopathology" title="Cytopathology">cytology</a>.<sup id="cite_ref-pmid21319315_9-1" class="reference"><a href="#cite_note-pmid21319315-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid21254456_10-1" class="reference"><a href="#cite_note-pmid21254456-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> In addition, the basaloid variant of SqCC can be difficult to distinguish from other poorly differentiated squamous cell carcinomas.<sup id="cite_ref-pmid12760288_11-0" class="reference"><a href="#cite_note-pmid12760288-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Treatment">Treatment</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Basaloid_squamous_cell_lung_carcinoma&action=edit&section=4" title="Edit section: Treatment"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>For last several decades of the 20th century, all histological variants of NSCLC were generally treated identically. In the last decade, it has become apparent that different variants of malignant tumors generally exhibit diverse genetic, biological, and clinical properties, including response to treatment.<sup id="cite_ref-RossiMarchioni_12-0" class="reference"><a href="#cite_note-RossiMarchioni-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid19672420_13-0" class="reference"><a href="#cite_note-pmid19672420-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup> </p><p>As patients with uncommon lung tumor variants, including tumors composed of mixtures of histological subtypes, tend to be excluded from <a href="/wiki/Clinical_trials" class="mw-redirect" title="Clinical trials">clinical trials</a>,<sup id="cite_ref-trials_14-0" class="reference"><a href="#cite_note-trials-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup> the most efficacious treatment regimen(s) for basaloid squamous cell carcinoma remain unknown. In general, these variants appear to be treated according to standard protocols in place for squamous cell carcinoma.<sup id="cite_ref-pmid14667594_15-0" class="reference"><a href="#cite_note-pmid14667594-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Prognosis">Prognosis</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Basaloid_squamous_cell_lung_carcinoma&action=edit&section=5" title="Edit section: Prognosis"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Like nearly all other forms of NSCLC, the prognosis of basaloid squamous cell carcinoma is quite poor.<sup id="cite_ref-pmid10492274_16-0" class="reference"><a href="#cite_note-pmid10492274-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup> </p><p>Although case numbers tend to be rather small, and the published studies <a href="/wiki/Statistical_power" class="mw-redirect" title="Statistical power">statistically underpowered</a>, much (but not all)<sup id="cite_ref-pmid14667594_15-1" class="reference"><a href="#cite_note-pmid14667594-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> evidence suggests that basaloid squamous cell lung carcinomas may have a somewhat worse prognosis than "conventional" (i.e. non-basaloid) squamous cell lung carcinomas.<sup id="cite_ref-pmid18094005_7-1" class="reference"><a href="#cite_note-pmid18094005-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid21269455_17-0" class="reference"><a href="#cite_note-pmid21269455-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid8194014_18-0" class="reference"><a href="#cite_note-pmid8194014-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup> As survival has been noted to be worse in basaloid variants at earlier tumor stages (i.e. Stages I and II), the decreased survival could be attributable to earlier distant <a href="/wiki/Metastasis" title="Metastasis">metastasis</a> appearing during the natural history of these tumors, as compared to other squamous cell carcinomas and NSCLCs in general.<sup id="cite_ref-pmid18094005_7-2" class="reference"><a href="#cite_note-pmid18094005-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Epidemiology">Epidemiology</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Basaloid_squamous_cell_lung_carcinoma&action=edit&section=6" title="Edit section: Epidemiology"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The true incidence and prevalence of basaloid squamous cell lung carcinoma remains unknown, but this form of lung cancer is considered relatively uncommon.<sup id="cite_ref-pmid21269455_17-1" class="reference"><a href="#cite_note-pmid21269455-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup> In one of the largest studies of this particular variant, Moro-Sibilot and co-workers found a 6.3% prevalence of Bas-SqCC among 1,418 consecutive NSCLC patients at their institution.<sup id="cite_ref-pmid18094005_7-3" class="reference"><a href="#cite_note-pmid18094005-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p><p>Basaloid carcinomas of the lung - like nearly all recognized variants of lung cancer - are highly associated with <a href="/wiki/Tobacco_smoking" title="Tobacco smoking">tobacco smoking</a>.<sup id="cite_ref-pmid18094005_7-4" class="reference"><a href="#cite_note-pmid18094005-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> Basaloid architecture in <a href="/wiki/Pulmonary" class="mw-redirect" title="Pulmonary">pulmonary</a> carcinomas has been shown to be particularly prevalent in smokers with heavy exposure,<sup id="cite_ref-pmid18094005_7-5" class="reference"><a href="#cite_note-pmid18094005-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> and squamous cell carcinoma has the strongest association with tobacco exposure than any other major cell type of NSCLC.<sup id="cite_ref-pmid6087006_19-0" class="reference"><a href="#cite_note-pmid6087006-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup> </p><p>As compared to other forms of lung cancer, Bas-SqCC often occurs in those who are somewhat older than average.<sup id="cite_ref-pmid18094005_7-6" class="reference"><a href="#cite_note-pmid18094005-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p><p>Basaloid squamous cell carcinoma usually begins <a href="/wiki/Hilum_of_lung" class="mw-redirect" title="Hilum of lung">centrally</a>, in the larger proximal <a href="/wiki/Bronchus" title="Bronchus">bronchi</a>.<sup id="cite_ref-pmid21269455_17-2" class="reference"><a href="#cite_note-pmid21269455-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup> Basaloid carcinoma primary in the <a href="/wiki/Lung" title="Lung">lung</a> may also occur in a multicentric form.<sup id="cite_ref-pmid18480394_20-0" class="reference"><a href="#cite_note-pmid18480394-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Basaloid_squamous_cell_lung_carcinoma&action=edit&section=7" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-who2004-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-who2004_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-who2004_1-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-who2004_1-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite id="CITEREFTravisBrambillaMuller-HermelinkHarris2004" class="citation book cs1">Travis, William D; Brambilla, Elisabeth; Muller-Hermelink, H Konrad; Harris, Curtis C, eds. (2004). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20090823210304/http://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb10/bb10-cover.pdf"><i>Pathology and Genetics of Tumours of the Lung, Pleura, Thymus and Heart</i></a> <span class="cs1-format">(PDF)</span>. World Health Organization Classification of Tumours. Lyon: IARC Press. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-92-832-2418-1" title="Special:BookSources/978-92-832-2418-1"><bdi>978-92-832-2418-1</bdi></a>. Archived from <a rel="nofollow" class="external text" href="http://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb10/bb10-cover.pdf">the original</a> <span class="cs1-format">(PDF)</span> on 23 August 2009<span class="reference-accessdate">. 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The <a href="/wiki/National_Cancer_Institute" title="National Cancer Institute">National Cancer Institute</a> site containing further reading and resources about lung cancer.</li> <li><a rel="nofollow" class="external autonumber" href="https://web.archive.org/web/20110721001056/http://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb10/BB10.pdf">[1]</a>. 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the lung">Giant-cell carcinoma</a></li> <li><a class="mw-selflink selflink">Basaloid squamous cell lung carcinoma</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Small-cell_carcinoma" title="Small-cell carcinoma">Small-cell carcinoma</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Combined_small-cell_lung_carcinoma" title="Combined small-cell lung carcinoma">Combined small-cell carcinoma</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Non-<a href="/wiki/Carcinoma" title="Carcinoma">carcinoma</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Sarcoma" title="Sarcoma">Sarcoma</a></li> <li><a href="/wiki/Lymphoma" title="Lymphoma">Lymphoma</a></li> <li><a href="/wiki/Immature_teratoma" 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