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overflow: hidden; text-overflow: ellipsis; -webkit-line-clamp: 3; -webkit-box-orient: vertical; }</style><div class="col-xs-12 clearfix"><div class="u-floatLeft"><h1 class="PageHeader-title u-m0x u-fs30">Temporal Lobe</h1><div class="u-tcGrayDark">62 Followers</div><div class="u-tcGrayDark u-mt2x">Recent papers in <b>Temporal Lobe</b></div></div></div></div></div></div><div class="TabbedNavigation"><div class="container"><div class="row"><div class="col-xs-12 clearfix"><ul class="nav u-m0x u-p0x list-inline u-displayFlex"><li class="active"><a href="https://www.academia.edu/Documents/in/Temporal_Lobe">Top Papers</a></li><li><a href="https://www.academia.edu/Documents/in/Temporal_Lobe/MostCited">Most Cited Papers</a></li><li><a href="https://www.academia.edu/Documents/in/Temporal_Lobe/MostDownloaded">Most Downloaded Papers</a></li><li><a href="https://www.academia.edu/Documents/in/Temporal_Lobe/MostRecent">Newest Papers</a></li><li><a class="" href="https://www.academia.edu/People/Temporal_Lobe">People</a></li></ul></div><style type="text/css">ul.nav{flex-direction:row}@media(max-width: 567px){ul.nav{flex-direction:column}.TabbedNavigation li{max-width:100%}.TabbedNavigation li.active{background-color:var(--background-grey, #dddde2)}.TabbedNavigation li.active:before,.TabbedNavigation li.active:after{display:none}}</style></div></div></div><div class="container"><div class="row"><div class="col-xs-12"><div class="u-displayFlex"><div class="u-flexGrow1"><div class="works"><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_56748836" data-work_id="56748836" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/56748836/New_Insights_Into_the_Anatomic_Dissection_of_the_Temporal_Stem_With_Special_Emphasis_on_the_Inferior_Fronto_occipital_Fasciculus">New Insights Into the Anatomic Dissection of the Temporal Stem With Special Emphasis on the Inferior Fronto-occipital Fasciculus</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objective: To analyze the 3-dimensional relationships of the inferior fronto-occipital fasciculus (IFOF) within the temporal stem using anatomic dissection and to study the surgical application. Methods: Ten postmortem human hemispheres... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_56748836" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objective: To analyze the 3-dimensional relationships of the inferior fronto-occipital fasciculus (IFOF) within the temporal stem using anatomic dissection and to study the surgical application. Methods: Ten postmortem human hemispheres (5 right, 5 left) were dissected using the Klingler fiber dissection technique. The 3-dimensional relationships of the IFOF with different landmarks of the temporal stem, insula, and temporal lobe were analyzed and measured. Results: An average distance of 10.9 mm (range, 8–15 mm) was observed between the limen insulae and the anterior edge of the IFOF under the inferior limiting sulcus of the insula. This anterior one-third of the temporal stem is crossed by the uncinate fasciculus. The IFOF crosses the posterior two-thirds of the temporal stem, in the space between the posterior limit of the uncinate fasciculus and the lateral geniculate body. The average superoinferior distance between the IFOF and the inferior limiting sulcus was 3.8 mm. The audi...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/56748836" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a36b7283e33e3d4471c245d8348987cd" rel="nofollow" data-download="{"attachment_id":71981002,"asset_id":56748836,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/71981002/download_file?st=MTc0MDE0MDM0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32375357" href="https://univ-montpellier.academia.edu/HuguesDuffau">Hugues Duffau</a><script data-card-contents-for-user="32375357" type="text/json">{"id":32375357,"first_name":"Hugues","last_name":"Duffau","domain_name":"univ-montpellier","page_name":"HuguesDuffau","display_name":"Hugues Duffau","profile_url":"https://univ-montpellier.academia.edu/HuguesDuffau?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_56748836 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="56748836"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 56748836, container: ".js-paper-rank-work_56748836", }); 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Methods: Ten postmortem human hemispheres (5 right, 5 left) were dissected using the Klingler fiber dissection technique. The 3-dimensional relationships of the IFOF with different landmarks of the temporal stem, insula, and temporal lobe were analyzed and measured. Results: An average distance of 10.9 mm (range, 8–15 mm) was observed between the limen insulae and the anterior edge of the IFOF under the inferior limiting sulcus of the insula. This anterior one-third of the temporal stem is crossed by the uncinate fasciculus. The IFOF crosses the posterior two-thirds of the temporal stem, in the space between the posterior limit of the uncinate fasciculus and the lateral geniculate body. The average superoinferior distance between the IFOF and the inferior limiting sulcus was 3.8 mm. The audi...","downloadable_attachments":[{"id":71981002,"asset_id":56748836,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32375357,"first_name":"Hugues","last_name":"Duffau","domain_name":"univ-montpellier","page_name":"HuguesDuffau","display_name":"Hugues Duffau","profile_url":"https://univ-montpellier.academia.edu/HuguesDuffau?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery?f_ri=57557","nofollow":true},{"id":650,"name":"Neurosurgery","url":"https://www.academia.edu/Documents/in/Neurosurgery?f_ri=57557","nofollow":true},{"id":18174,"name":"Language","url":"https://www.academia.edu/Documents/in/Language?f_ri=57557","nofollow":true},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557","nofollow":true},{"id":76383,"name":"Glioma","url":"https://www.academia.edu/Documents/in/Glioma?f_ri=57557"},{"id":78467,"name":"Cerebral Cortex","url":"https://www.academia.edu/Documents/in/Cerebral_Cortex?f_ri=57557"},{"id":123404,"name":"Verbal behavior","url":"https://www.academia.edu/Documents/in/Verbal_behavior?f_ri=57557"},{"id":181792,"name":"Dissection","url":"https://www.academia.edu/Documents/in/Dissection?f_ri=57557"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=57557"},{"id":704401,"name":"Neural pathways","url":"https://www.academia.edu/Documents/in/Neural_pathways?f_ri=57557"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=57557"},{"id":1257483,"name":"Frontal Lobe","url":"https://www.academia.edu/Documents/in/Frontal_Lobe?f_ri=57557"},{"id":1425045,"name":"Brain Neoplasms","url":"https://www.academia.edu/Documents/in/Brain_Neoplasms?f_ri=57557"},{"id":1766624,"name":"Occipital Lobe","url":"https://www.academia.edu/Documents/in/Occipital_Lobe?f_ri=57557"},{"id":2463621,"name":"Postoperative Complications","url":"https://www.academia.edu/Documents/in/Postoperative_Complications?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_33140275" data-work_id="33140275" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/33140275/Visual_rating_and_volumetry_of_the_medial_temporal_lobe_on_magnetic_resonance_imaging_in_dementia_a_comparative_study">Visual rating and volumetry of the medial temporal lobe on magnetic resonance imaging in dementia: a comparative study</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objectives-It has been shown that atrophy of medial temporal lobe structures such as the hippocampus and entorhinal cortex shown on MRI may distinguish patients with Alzheimer's disease from healthy controls. However, the diagnostic value... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_33140275" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objectives-It has been shown that atrophy of medial temporal lobe structures such as the hippocampus and entorhinal cortex shown on MRI may distinguish patients with Alzheimer's disease from healthy controls. However, the diagnostic value of visual inspection and volumetry of medial temporal lobe atrophy (MTA) on MRI in a clinical setting is insuYciently known. Methods-Medial temporal lobe atrophy in 143 patients was visually rated from hard copies, using a 0-4 rating scale and a comparison was made with the volumes (cm 3 ) of the medial temporal lobe as estimated with volumetry, using a stereological method. All patients were recruited in an unselected way in a clinical setting in the centre for memory impairments at the Huddinge University Hospital. Patients with Alzheimer's disease (n=41), patients with other dementias (vascular dementia, frontotemporal dementia, and unspecified dementia; n=36) as well as non-demented subjects (n=66) were included. Medial temporal atrophy and volumetry were evaluated as a diagnostic tool by performing logistic regression analysis including age, sex, and mini mental state examination (MMSE) score and calculating the sensitivity and specificity and percentage correct classification.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/33140275" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="0f1a6710c26b751fd8eb735b527ee9df" rel="nofollow" data-download="{"attachment_id":53230681,"asset_id":33140275,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/53230681/download_file?st=MTc0MDE0MDM0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="64605148" href="https://independent.academia.edu/PerJulin">Per Julin</a><script data-card-contents-for-user="64605148" type="text/json">{"id":64605148,"first_name":"Per","last_name":"Julin","domain_name":"independent","page_name":"PerJulin","display_name":"Per Julin","profile_url":"https://independent.academia.edu/PerJulin?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_33140275 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="33140275"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 33140275, container: ".js-paper-rank-work_33140275", }); 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$(".js-view-count[data-work-id=33140275]").text(description); $(".js-view-count-work_33140275").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_33140275").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="33140275"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">20</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="623" rel="nofollow" href="https://www.academia.edu/Documents/in/Neurology">Neurology</a>, <script data-card-contents-for-ri="623" type="text/json">{"id":623,"name":"Neurology","url":"https://www.academia.edu/Documents/in/Neurology?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="640" rel="nofollow" href="https://www.academia.edu/Documents/in/Radiology">Radiology</a>, <script data-card-contents-for-ri="640" type="text/json">{"id":640,"name":"Radiology","url":"https://www.academia.edu/Documents/in/Radiology?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="23890" rel="nofollow" href="https://www.academia.edu/Documents/in/Comparative_Study">Comparative Study</a><script data-card-contents-for-ri="23890" type="text/json">{"id":23890,"name":"Comparative Study","url":"https://www.academia.edu/Documents/in/Comparative_Study?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=33140275]'), work: {"id":33140275,"title":"Visual rating and volumetry of the medial temporal lobe on magnetic resonance imaging in dementia: a comparative study","created_at":"2017-05-22T05:23:27.437-07:00","url":"https://www.academia.edu/33140275/Visual_rating_and_volumetry_of_the_medial_temporal_lobe_on_magnetic_resonance_imaging_in_dementia_a_comparative_study?f_ri=57557","dom_id":"work_33140275","summary":"Objectives-It has been shown that atrophy of medial temporal lobe structures such as the hippocampus and entorhinal cortex shown on MRI may distinguish patients with Alzheimer's disease from healthy controls. However, the diagnostic value of visual inspection and volumetry of medial temporal lobe atrophy (MTA) on MRI in a clinical setting is insuYciently known. Methods-Medial temporal lobe atrophy in 143 patients was visually rated from hard copies, using a 0-4 rating scale and a comparison was made with the volumes (cm 3 ) of the medial temporal lobe as estimated with volumetry, using a stereological method. All patients were recruited in an unselected way in a clinical setting in the centre for memory impairments at the Huddinge University Hospital. Patients with Alzheimer's disease (n=41), patients with other dementias (vascular dementia, frontotemporal dementia, and unspecified dementia; n=36) as well as non-demented subjects (n=66) were included. Medial temporal atrophy and volumetry were evaluated as a diagnostic tool by performing logistic regression analysis including age, sex, and mini mental state examination (MMSE) score and calculating the sensitivity and specificity and percentage correct classification.","downloadable_attachments":[{"id":53230681,"asset_id":33140275,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":64605148,"first_name":"Per","last_name":"Julin","domain_name":"independent","page_name":"PerJulin","display_name":"Per Julin","profile_url":"https://independent.academia.edu/PerJulin?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":623,"name":"Neurology","url":"https://www.academia.edu/Documents/in/Neurology?f_ri=57557","nofollow":true},{"id":640,"name":"Radiology","url":"https://www.academia.edu/Documents/in/Radiology?f_ri=57557","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":23890,"name":"Comparative Study","url":"https://www.academia.edu/Documents/in/Comparative_Study?f_ri=57557","nofollow":true},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":97766,"name":"Vascular dementia","url":"https://www.academia.edu/Documents/in/Vascular_dementia?f_ri=57557"},{"id":125564,"name":"Statistical Significance","url":"https://www.academia.edu/Documents/in/Statistical_Significance?f_ri=57557"},{"id":212320,"name":"Logistic Regression Analysis","url":"https://www.academia.edu/Documents/in/Logistic_Regression_Analysis?f_ri=57557"},{"id":245071,"name":"Rating Scale","url":"https://www.academia.edu/Documents/in/Rating_Scale?f_ri=57557"},{"id":254133,"name":"Mini Mental State Examination","url":"https://www.academia.edu/Documents/in/Mini_Mental_State_Examination?f_ri=57557"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=57557"},{"id":319071,"name":"Entorhinal Cortex","url":"https://www.academia.edu/Documents/in/Entorhinal_Cortex?f_ri=57557"},{"id":357850,"name":"Atrophy","url":"https://www.academia.edu/Documents/in/Atrophy?f_ri=57557"},{"id":413194,"name":"Analysis of Variance","url":"https://www.academia.edu/Documents/in/Analysis_of_Variance?f_ri=57557"},{"id":430721,"name":"Frontotemporal Dementia","url":"https://www.academia.edu/Documents/in/Frontotemporal_Dementia?f_ri=57557"},{"id":609835,"name":"Medial Temporal Lobe","url":"https://www.academia.edu/Documents/in/Medial_Temporal_Lobe?f_ri=57557"},{"id":901876,"name":"Sensitivity and Specificity","url":"https://www.academia.edu/Documents/in/Sensitivity_and_Specificity?f_ri=57557"},{"id":1120234,"name":"Alzheimer Disease","url":"https://www.academia.edu/Documents/in/Alzheimer_Disease?f_ri=57557"},{"id":2364406,"name":"Visual Inspection","url":"https://www.academia.edu/Documents/in/Visual_Inspection?f_ri=57557"},{"id":2439414,"name":"Magnetic resonance image","url":"https://www.academia.edu/Documents/in/Magnetic_resonance_image?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_404063" data-work_id="404063" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/404063/Musicians_Differ_From_Nonmusicians_In_Brain_Activation_Despite_Performance_Matching">Musicians Differ From Nonmusicians In Brain Activation Despite Performance Matching</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/404063" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="3640dbcfd198219992573aefe1d01b6a" rel="nofollow" data-download="{"attachment_id":51421606,"asset_id":404063,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/51421606/download_file?st=MTc0MDE0MDM0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="305346" href="https://hms-harvard.academia.edu/NadineGaab">Nadine Gaab</a><script data-card-contents-for-user="305346" type="text/json">{"id":305346,"first_name":"Nadine","last_name":"Gaab","domain_name":"hms-harvard","page_name":"NadineGaab","display_name":"Nadine Gaab","profile_url":"https://hms-harvard.academia.edu/NadineGaab?f_ri=57557","photo":"https://0.academia-photos.com/305346/75327/82142/s65_nadine.gaab.jpg"}</script></span></span></li><li class="js-paper-rank-work_404063 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="404063"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 404063, container: ".js-paper-rank-work_404063", }); });</script></li><li class="js-percentile-work_404063 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 404063; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_404063"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_404063 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="404063"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 404063; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=404063]").text(description); $(".js-view-count-work_404063").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_404063").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="404063"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">11</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="671" rel="nofollow" href="https://www.academia.edu/Documents/in/Music">Music</a>, <script data-card-contents-for-ri="671" type="text/json">{"id":671,"name":"Music","url":"https://www.academia.edu/Documents/in/Music?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="9043" rel="nofollow" href="https://www.academia.edu/Documents/in/Performance">Performance</a>, <script data-card-contents-for-ri="9043" type="text/json">{"id":9043,"name":"Performance","url":"https://www.academia.edu/Documents/in/Performance?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a><script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=404063]'), work: {"id":404063,"title":"Musicians Differ From Nonmusicians In Brain Activation Despite Performance Matching","created_at":"2011-01-05T23:12:02.656-08:00","url":"https://www.academia.edu/404063/Musicians_Differ_From_Nonmusicians_In_Brain_Activation_Despite_Performance_Matching?f_ri=57557","dom_id":"work_404063","summary":null,"downloadable_attachments":[{"id":51421606,"asset_id":404063,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":305346,"first_name":"Nadine","last_name":"Gaab","domain_name":"hms-harvard","page_name":"NadineGaab","display_name":"Nadine Gaab","profile_url":"https://hms-harvard.academia.edu/NadineGaab?f_ri=57557","photo":"https://0.academia-photos.com/305346/75327/82142/s65_nadine.gaab.jpg"}],"research_interests":[{"id":671,"name":"Music","url":"https://www.academia.edu/Documents/in/Music?f_ri=57557","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":9043,"name":"Performance","url":"https://www.academia.edu/Documents/in/Performance?f_ri=57557","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=57557","nofollow":true},{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary?f_ri=57557"},{"id":46858,"name":"Memory","url":"https://www.academia.edu/Documents/in/Memory?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":154341,"name":"Pitch Perception","url":"https://www.academia.edu/Documents/in/Pitch_Perception?f_ri=57557"},{"id":406036,"name":"Parietal Lobe","url":"https://www.academia.edu/Documents/in/Parietal_Lobe?f_ri=57557"},{"id":1008093,"name":"Occupations","url":"https://www.academia.edu/Documents/in/Occupations?f_ri=57557"},{"id":1257483,"name":"Frontal Lobe","url":"https://www.academia.edu/Documents/in/Frontal_Lobe?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_13648893" data-work_id="13648893" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13648893/Serum_prolactin_levels_after_seizure_and_syncopal_attacks">Serum prolactin levels after seizure and syncopal attacks</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Loss of consciousness and falling are the key features of syncope. Common accompaniments include tonic and myoclonic muscle activity, eye deviations, automatisms, vocalizations and hallucinations that may render the distinction from... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_13648893" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Loss of consciousness and falling are the key features of syncope. Common accompaniments include tonic and myoclonic muscle activity, eye deviations, automatisms, vocalizations and hallucinations that may render the distinction from epileptic seizures difficult. The frequently increased levels of serum prolactin (SPRL) were observed immediately after generalized and complex partial seizures. Presumably, the hormone release is caused by the propagation of epileptic activity, usually from the temporal lobe to the hypothalamic pituitary axis. Numerous reports have demonstrated that the post-ictal SPRL level may be used to differentiate between epileptic and syncopal, non-epileptic attacks. In order to confirm the hypothesis, the SPRL levels were measured in patients with compex partial seizures (CPS) and patients with vaso-vagal syncopal attacks (VVS). The SPRL levels were prospectively measured for each patient as soon as possible after the event (within 1 hour), then 1 hour after the first determination and finally blood was sampled 24 hours later. During the study period (18 months), 18 patients with CPS and 15 patients with VVS were investigated in total. The mean values of SPRL levels in both groups were increased immediately after the event (CPS group: 1142 ± 305 mIU/l; VVS group: 874 ± 208 mIU/l). The elevated SPRL levels were found in 14 (78%) patients immediately after CPS and in 9 (60%) patients immediately after VVS. After examining the results of the present study we conclude that the elevated serum prolactin level after an epileptic attack is of no significant value in differential diagnosis between epileptic and vaso-vagal syncopal attacks.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13648893" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="40f7a33bb4c29a1462637f93d0757d5a" rel="nofollow" data-download="{"attachment_id":45108987,"asset_id":13648893,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45108987/download_file?st=MTc0MDE0MDM0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32805117" href="https://independent.academia.edu/Vesna%C4%8Capkun">Vesna Čapkun</a><script data-card-contents-for-user="32805117" type="text/json">{"id":32805117,"first_name":"Vesna","last_name":"Čapkun","domain_name":"independent","page_name":"VesnaČapkun","display_name":"Vesna Čapkun","profile_url":"https://independent.academia.edu/Vesna%C4%8Capkun?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_13648893 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="13648893"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 13648893, container: ".js-paper-rank-work_13648893", }); });</script></li><li class="js-percentile-work_13648893 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 13648893; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_13648893"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_13648893 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="13648893"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 13648893; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=13648893]").text(description); $(".js-view-count-work_13648893").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_13648893").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="13648893"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">11</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="51686" rel="nofollow" href="https://www.academia.edu/Documents/in/Seizure">Seizure</a>, <script data-card-contents-for-ri="51686" type="text/json">{"id":51686,"name":"Seizure","url":"https://www.academia.edu/Documents/in/Seizure?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="57557" rel="nofollow" href="https://www.academia.edu/Documents/in/Temporal_Lobe">Temporal Lobe</a>, <script data-card-contents-for-ri="57557" type="text/json">{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="64657" rel="nofollow" href="https://www.academia.edu/Documents/in/Prolactin">Prolactin</a><script data-card-contents-for-ri="64657" type="text/json">{"id":64657,"name":"Prolactin","url":"https://www.academia.edu/Documents/in/Prolactin?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=13648893]'), work: {"id":13648893,"title":"Serum prolactin levels after seizure and syncopal attacks","created_at":"2015-07-05T04:50:07.929-07:00","url":"https://www.academia.edu/13648893/Serum_prolactin_levels_after_seizure_and_syncopal_attacks?f_ri=57557","dom_id":"work_13648893","summary":"Loss of consciousness and falling are the key features of syncope. Common accompaniments include tonic and myoclonic muscle activity, eye deviations, automatisms, vocalizations and hallucinations that may render the distinction from epileptic seizures difficult. The frequently increased levels of serum prolactin (SPRL) were observed immediately after generalized and complex partial seizures. Presumably, the hormone release is caused by the propagation of epileptic activity, usually from the temporal lobe to the hypothalamic pituitary axis. Numerous reports have demonstrated that the post-ictal SPRL level may be used to differentiate between epileptic and syncopal, non-epileptic attacks. In order to confirm the hypothesis, the SPRL levels were measured in patients with compex partial seizures (CPS) and patients with vaso-vagal syncopal attacks (VVS). The SPRL levels were prospectively measured for each patient as soon as possible after the event (within 1 hour), then 1 hour after the first determination and finally blood was sampled 24 hours later. During the study period (18 months), 18 patients with CPS and 15 patients with VVS were investigated in total. The mean values of SPRL levels in both groups were increased immediately after the event (CPS group: 1142 ± 305 mIU/l; VVS group: 874 ± 208 mIU/l). The elevated SPRL levels were found in 14 (78%) patients immediately after CPS and in 9 (60%) patients immediately after VVS. After examining the results of the present study we conclude that the elevated serum prolactin level after an epileptic attack is of no significant value in differential diagnosis between epileptic and vaso-vagal syncopal attacks.","downloadable_attachments":[{"id":45108987,"asset_id":13648893,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32805117,"first_name":"Vesna","last_name":"Čapkun","domain_name":"independent","page_name":"VesnaČapkun","display_name":"Vesna Čapkun","profile_url":"https://independent.academia.edu/Vesna%C4%8Capkun?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true},{"id":51686,"name":"Seizure","url":"https://www.academia.edu/Documents/in/Seizure?f_ri=57557","nofollow":true},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557","nofollow":true},{"id":64657,"name":"Prolactin","url":"https://www.academia.edu/Documents/in/Prolactin?f_ri=57557","nofollow":true},{"id":162159,"name":"Differential Diagnosis","url":"https://www.academia.edu/Documents/in/Differential_Diagnosis?f_ri=57557"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=57557"},{"id":651604,"name":"Seizures","url":"https://www.academia.edu/Documents/in/Seizures?f_ri=57557"},{"id":1151938,"name":"Loss of Consciousness","url":"https://www.academia.edu/Documents/in/Loss_of_Consciousness?f_ri=57557"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=57557"},{"id":1300379,"name":"Muscle Activity","url":"https://www.academia.edu/Documents/in/Muscle_Activity?f_ri=57557"},{"id":1318932,"name":"Predictive value of tests","url":"https://www.academia.edu/Documents/in/Predictive_value_of_tests?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_69628934" data-work_id="69628934" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/69628934/Lexical_Preactivation_in_Basic_Linguistic_Phrases">Lexical Preactivation in Basic Linguistic Phrases</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">■ Many previous studies have shown that predictable words are read faster and lead to reduced neural activation, consistent with a model of reading in which words are activated in advance of being encountered. The nature of such... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_69628934" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">■ Many previous studies have shown that predictable words are read faster and lead to reduced neural activation, consistent with a model of reading in which words are activated in advance of being encountered. The nature of such preactivation, however, has typ-ically been studied indirectly through its subsequent effect on word recognition. Here, we use magnetoencephalography to study the dynamics of prediction within serially presented adjective–noun phrases, beginning at the point at which the pre-dictive information is first available to the reader. Using corpus transitional probability to estimate the predictability of a noun, we found an increase in activity in the left middle temporal gyrus in response to the presentation of highly predictive adjectives (i.e., adjectives that license a strong noun prediction). Moreover, we found that adjective predictivity and expected noun frequency interacted, such that the response to the highly predictive adjec-tives (e.g., stainless) was ...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/69628934" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="dbaf8bba2efb1e4018867d40e45a829b" rel="nofollow" data-download="{"attachment_id":79650896,"asset_id":69628934,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/79650896/download_file?st=MTc0MDE0MDM0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33442100" href="https://nyu.academia.edu/AlecMarantz">Alec Marantz</a><script data-card-contents-for-user="33442100" type="text/json">{"id":33442100,"first_name":"Alec","last_name":"Marantz","domain_name":"nyu","page_name":"AlecMarantz","display_name":"Alec Marantz","profile_url":"https://nyu.academia.edu/AlecMarantz?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_69628934 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="69628934"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 69628934, container: ".js-paper-rank-work_69628934", }); });</script></li><li class="js-percentile-work_69628934 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 69628934; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_69628934"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_69628934 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="69628934"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 69628934; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=69628934]").text(description); $(".js-view-count-work_69628934").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_69628934").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="69628934"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">12</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="237" rel="nofollow" href="https://www.academia.edu/Documents/in/Cognitive_Science">Cognitive Science</a>, <script data-card-contents-for-ri="237" type="text/json">{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="422" rel="nofollow" href="https://www.academia.edu/Documents/in/Computer_Science">Computer Science</a>, <script data-card-contents-for-ri="422" type="text/json">{"id":422,"name":"Computer Science","url":"https://www.academia.edu/Documents/in/Computer_Science?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4972" rel="nofollow" href="https://www.academia.edu/Documents/in/Psycholinguistics">Psycholinguistics</a><script data-card-contents-for-ri="4972" type="text/json">{"id":4972,"name":"Psycholinguistics","url":"https://www.academia.edu/Documents/in/Psycholinguistics?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=69628934]'), work: {"id":69628934,"title":"Lexical Preactivation in Basic Linguistic Phrases","created_at":"2022-01-27T05:34:16.769-08:00","url":"https://www.academia.edu/69628934/Lexical_Preactivation_in_Basic_Linguistic_Phrases?f_ri=57557","dom_id":"work_69628934","summary":"■ Many previous studies have shown that predictable words are read faster and lead to reduced neural activation, consistent with a model of reading in which words are activated in advance of being encountered. The nature of such preactivation, however, has typ-ically been studied indirectly through its subsequent effect on word recognition. Here, we use magnetoencephalography to study the dynamics of prediction within serially presented adjective–noun phrases, beginning at the point at which the pre-dictive information is first available to the reader. Using corpus transitional probability to estimate the predictability of a noun, we found an increase in activity in the left middle temporal gyrus in response to the presentation of highly predictive adjectives (i.e., adjectives that license a strong noun prediction). Moreover, we found that adjective predictivity and expected noun frequency interacted, such that the response to the highly predictive adjec-tives (e.g., stainless) was ...","downloadable_attachments":[{"id":79650896,"asset_id":69628934,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33442100,"first_name":"Alec","last_name":"Marantz","domain_name":"nyu","page_name":"AlecMarantz","display_name":"Alec Marantz","profile_url":"https://nyu.academia.edu/AlecMarantz?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true},{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true},{"id":422,"name":"Computer Science","url":"https://www.academia.edu/Documents/in/Computer_Science?f_ri=57557","nofollow":true},{"id":4972,"name":"Psycholinguistics","url":"https://www.academia.edu/Documents/in/Psycholinguistics?f_ri=57557","nofollow":true},{"id":5356,"name":"Magnetoencephalography","url":"https://www.academia.edu/Documents/in/Magnetoencephalography?f_ri=57557"},{"id":9471,"name":"Reading","url":"https://www.academia.edu/Documents/in/Reading?f_ri=57557"},{"id":21548,"name":"Cognitive Neuroscience","url":"https://www.academia.edu/Documents/in/Cognitive_Neuroscience?f_ri=57557"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=57557"},{"id":28576,"name":"Prefrontal Cortex","url":"https://www.academia.edu/Documents/in/Prefrontal_Cortex?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=57557"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_52753014" data-work_id="52753014" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/52753014/Medial_temporal_lobe_dysgenesis_in_hypochondroplasia">Medial temporal lobe dysgenesis in hypochondroplasia</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">We describe two patients who have hypochondroplasia with medial temporal lobe dysgenesis. This association has only been reported once before. Both patients had an FGFR3 mutation: 1620C ! A, resulting in Asn540Lys. FGFR3 is expressed in... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_52753014" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">We describe two patients who have hypochondroplasia with medial temporal lobe dysgenesis. This association has only been reported once before. Both patients had an FGFR3 mutation: 1620C ! A, resulting in Asn540Lys. FGFR3 is expressed in the brain during development and plays a role in hippocampal formation. We suggest FGFR3 mutations might cause cerebral malformations in hypochondroplasia as well as in thanatophoric dysplasia. Further neuroimaging studies of patients with hypochondroplasia and epilepsy or developmental delay may clarify the proportion of patients with hypochondroplasia who have this pattern of central nervous system abnormalities.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/52753014" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="97a728cebfad3e2487ee8eaf8f793c87" rel="nofollow" data-download="{"attachment_id":69866975,"asset_id":52753014,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/69866975/download_file?st=MTc0MDE0MDM0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32784647" href="https://unimelb.academia.edu/SimoneMandelstam">Simone Mandelstam</a><script data-card-contents-for-user="32784647" type="text/json">{"id":32784647,"first_name":"Simone","last_name":"Mandelstam","domain_name":"unimelb","page_name":"SimoneMandelstam","display_name":"Simone Mandelstam","profile_url":"https://unimelb.academia.edu/SimoneMandelstam?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_52753014 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="52753014"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 52753014, container: ".js-paper-rank-work_52753014", }); });</script></li><li class="js-percentile-work_52753014 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 52753014; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_52753014"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_52753014 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="52753014"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 52753014; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=52753014]").text(description); $(".js-view-count-work_52753014").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_52753014").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="52753014"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">8</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="156" rel="nofollow" href="https://www.academia.edu/Documents/in/Genetics">Genetics</a>, <script data-card-contents-for-ri="156" type="text/json">{"id":156,"name":"Genetics","url":"https://www.academia.edu/Documents/in/Genetics?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="2639" rel="nofollow" href="https://www.academia.edu/Documents/in/Neuroimaging">Neuroimaging</a>, <script data-card-contents-for-ri="2639" type="text/json">{"id":2639,"name":"Neuroimaging","url":"https://www.academia.edu/Documents/in/Neuroimaging?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="57557" rel="nofollow" href="https://www.academia.edu/Documents/in/Temporal_Lobe">Temporal Lobe</a><script data-card-contents-for-ri="57557" type="text/json">{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=52753014]'), work: {"id":52753014,"title":"Medial temporal lobe dysgenesis in hypochondroplasia","created_at":"2021-09-18T16:36:29.766-07:00","url":"https://www.academia.edu/52753014/Medial_temporal_lobe_dysgenesis_in_hypochondroplasia?f_ri=57557","dom_id":"work_52753014","summary":"We describe two patients who have hypochondroplasia with medial temporal lobe dysgenesis. This association has only been reported once before. Both patients had an FGFR3 mutation: 1620C ! A, resulting in Asn540Lys. FGFR3 is expressed in the brain during development and plays a role in hippocampal formation. We suggest FGFR3 mutations might cause cerebral malformations in hypochondroplasia as well as in thanatophoric dysplasia. Further neuroimaging studies of patients with hypochondroplasia and epilepsy or developmental delay may clarify the proportion of patients with hypochondroplasia who have this pattern of central nervous system abnormalities.","downloadable_attachments":[{"id":69866975,"asset_id":52753014,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32784647,"first_name":"Simone","last_name":"Mandelstam","domain_name":"unimelb","page_name":"SimoneMandelstam","display_name":"Simone Mandelstam","profile_url":"https://unimelb.academia.edu/SimoneMandelstam?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":156,"name":"Genetics","url":"https://www.academia.edu/Documents/in/Genetics?f_ri=57557","nofollow":true},{"id":2639,"name":"Neuroimaging","url":"https://www.academia.edu/Documents/in/Neuroimaging?f_ri=57557","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557","nofollow":true},{"id":151448,"name":"American","url":"https://www.academia.edu/Documents/in/American?f_ri=57557"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=57557"},{"id":253560,"name":"Newborn Infant","url":"https://www.academia.edu/Documents/in/Newborn_Infant?f_ri=57557"},{"id":609835,"name":"Medial Temporal Lobe","url":"https://www.academia.edu/Documents/in/Medial_Temporal_Lobe?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_48168499" data-work_id="48168499" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/48168499/Neural_Foundations_for_Understanding_Social_and_Mechanical_Concepts">Neural Foundations for Understanding Social and Mechanical Concepts</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Motivated by neuropsychological investigations of category-specific impairments, many functional brain imaging studies have found distinct patterns of neural activity associated with different object categories. However, the extent to... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_48168499" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Motivated by neuropsychological investigations of category-specific impairments, many functional brain imaging studies have found distinct patterns of neural activity associated with different object categories. However, the extent to which these category-related activation patterns reflect differences in conceptual representation remains controversial. To investigate this issue, functional magnetic resonance imaging (fMRI) was used to record changes in neural activity while subjects interpreted animated vignettes composed of simple geometric shapes in motion. Vignettes interpreted as conveying social interactions elicited a distinct and distributed pattern of neural activity, relative to vignettes interpreted as mechanical actions. This neural system included regions in posterior temporal cortex associated with identifying human faces and other biological objects. In contrast, vignettes interpreted as conveying mechanical actions resulted in activity in posterior temporal lobe sites associated with identifying manipulable objects such as tools. Moreover, social, but not mechanical, interpretations elicited activity in regions implicated in the perception and modulation of emotion (right amygdala and ventromedial prefrontal cortex). Perceiving and understanding social and mechanical concepts depends, in part, on activity in distinct neural networks. Within the social domain, the network includes regions involved in processing and storing information about the form and motion of biological objects, and in perceiving, expressing, and regulating affective responses.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/48168499" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="3c09b387fe401cc05306f2cd7b76df1b" rel="nofollow" data-download="{"attachment_id":66920815,"asset_id":48168499,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/66920815/download_file?st=MTc0MDE0MDM0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="28601658" href="https://independent.academia.edu/alexmartin39">alex martin</a><script data-card-contents-for-user="28601658" type="text/json">{"id":28601658,"first_name":"alex","last_name":"martin","domain_name":"independent","page_name":"alexmartin39","display_name":"alex martin","profile_url":"https://independent.academia.edu/alexmartin39?f_ri=57557","photo":"https://0.academia-photos.com/28601658/130084751/119490633/s65_alex.martin.png"}</script></span></span></li><li class="js-paper-rank-work_48168499 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="48168499"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 48168499, container: ".js-paper-rank-work_48168499", }); });</script></li><li class="js-percentile-work_48168499 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 48168499; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_48168499"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_48168499 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="48168499"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 48168499; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=48168499]").text(description); $(".js-view-count-work_48168499").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_48168499").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="48168499"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">20</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="146" rel="nofollow" href="https://www.academia.edu/Documents/in/Bioinformatics">Bioinformatics</a>, <script data-card-contents-for-ri="146" type="text/json">{"id":146,"name":"Bioinformatics","url":"https://www.academia.edu/Documents/in/Bioinformatics?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="237" rel="nofollow" href="https://www.academia.edu/Documents/in/Cognitive_Science">Cognitive Science</a>, <script data-card-contents-for-ri="237" type="text/json">{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4212" rel="nofollow" href="https://www.academia.edu/Documents/in/Cognition">Cognition</a><script data-card-contents-for-ri="4212" type="text/json">{"id":4212,"name":"Cognition","url":"https://www.academia.edu/Documents/in/Cognition?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=48168499]'), work: {"id":48168499,"title":"Neural Foundations for Understanding Social and Mechanical Concepts","created_at":"2021-05-04T03:15:39.917-07:00","url":"https://www.academia.edu/48168499/Neural_Foundations_for_Understanding_Social_and_Mechanical_Concepts?f_ri=57557","dom_id":"work_48168499","summary":"Motivated by neuropsychological investigations of category-specific impairments, many functional brain imaging studies have found distinct patterns of neural activity associated with different object categories. However, the extent to which these category-related activation patterns reflect differences in conceptual representation remains controversial. To investigate this issue, functional magnetic resonance imaging (fMRI) was used to record changes in neural activity while subjects interpreted animated vignettes composed of simple geometric shapes in motion. Vignettes interpreted as conveying social interactions elicited a distinct and distributed pattern of neural activity, relative to vignettes interpreted as mechanical actions. This neural system included regions in posterior temporal cortex associated with identifying human faces and other biological objects. In contrast, vignettes interpreted as conveying mechanical actions resulted in activity in posterior temporal lobe sites associated with identifying manipulable objects such as tools. Moreover, social, but not mechanical, interpretations elicited activity in regions implicated in the perception and modulation of emotion (right amygdala and ventromedial prefrontal cortex). Perceiving and understanding social and mechanical concepts depends, in part, on activity in distinct neural networks. Within the social domain, the network includes regions involved in processing and storing information about the form and motion of biological objects, and in perceiving, expressing, and regulating affective responses.","downloadable_attachments":[{"id":66920815,"asset_id":48168499,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":28601658,"first_name":"alex","last_name":"martin","domain_name":"independent","page_name":"alexmartin39","display_name":"alex martin","profile_url":"https://independent.academia.edu/alexmartin39?f_ri=57557","photo":"https://0.academia-photos.com/28601658/130084751/119490633/s65_alex.martin.png"}],"research_interests":[{"id":146,"name":"Bioinformatics","url":"https://www.academia.edu/Documents/in/Bioinformatics?f_ri=57557","nofollow":true},{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true},{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true},{"id":4212,"name":"Cognition","url":"https://www.academia.edu/Documents/in/Cognition?f_ri=57557","nofollow":true},{"id":4715,"name":"Social Interaction","url":"https://www.academia.edu/Documents/in/Social_Interaction?f_ri=57557"},{"id":8014,"name":"Life Sciences","url":"https://www.academia.edu/Documents/in/Life_Sciences?f_ri=57557"},{"id":8780,"name":"Cognitive Neuropsychology","url":"https://www.academia.edu/Documents/in/Cognitive_Neuropsychology?f_ri=57557"},{"id":9189,"name":"Semantic Memory","url":"https://www.academia.edu/Documents/in/Semantic_Memory?f_ri=57557"},{"id":26066,"name":"Neural Network","url":"https://www.academia.edu/Documents/in/Neural_Network?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":66744,"name":"Biomedical Research","url":"https://www.academia.edu/Documents/in/Biomedical_Research?f_ri=57557"},{"id":90016,"name":"Topography","url":"https://www.academia.edu/Documents/in/Topography?f_ri=57557"},{"id":100946,"name":"Functional Imaging","url":"https://www.academia.edu/Documents/in/Functional_Imaging?f_ri=57557"},{"id":207162,"name":"Temporal Cortex","url":"https://www.academia.edu/Documents/in/Temporal_Cortex?f_ri=57557"},{"id":244565,"name":"Concept","url":"https://www.academia.edu/Documents/in/Concept?f_ri=57557"},{"id":1024379,"name":"Nuclear Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Nuclear_Magnetic_Resonance_Imaging?f_ri=57557"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=57557"},{"id":1565778,"name":"Ventromedial Prefrontal Cortex","url":"https://www.academia.edu/Documents/in/Ventromedial_Prefrontal_Cortex?f_ri=57557"},{"id":2580439,"name":"Functional brain imaging","url":"https://www.academia.edu/Documents/in/Functional_brain_imaging?f_ri=57557"},{"id":3922190,"name":"Activity pattern","url":"https://www.academia.edu/Documents/in/Activity_pattern?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_31330989" data-work_id="31330989" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/31330989/Influence_of_Stimulus_Salience_and_Attentional_Demands_on_Visual_Search_Patterns_in_Hemispatial_Neglect">Influence of Stimulus Salience and Attentional Demands on Visual Search Patterns in Hemispatial Neglect</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Seventy-five left and right brain-damaged patients, with or without hemispatial neglect, and 40 age-matched control subjects were tested on cancellation tasks with two different visual textures modeled after Julesz (1981). In one... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_31330989" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Seventy-five left and right brain-damaged patients, with or without hemispatial neglect, and 40 age-matched control subjects were tested on cancellation tasks with two different visual textures modeled after Julesz (1981). In one condition (''preattentive''), target elements segregated easily from background elements and were perceived effortlessly. In the other (''attentive''), target elements did not segregate easily and could be detected only after prolonged focal scrutiny. Both controls and patients were more accurate and faster on the preattentive than attentive texture. However, only neglect patients were disproportionately impaired on the attentive texture, thus suggesting that unilateral neglect is exacerbated by the low visual salience of the stimuli and a higher engagement of focal attention. Thus, a simple bedside test may help to tell apart the level of visual information processing maximally impaired in neglect patients.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/31330989" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="5c76d4c0d7118c9d593934ec423113c1" rel="nofollow" data-download="{"attachment_id":51718146,"asset_id":31330989,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/51718146/download_file?st=MTc0MDE0MDM0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="31695561" href="https://independent.academia.edu/SalvatoreMariaAglioti">Salvatore Maria Aglioti</a><script data-card-contents-for-user="31695561" type="text/json">{"id":31695561,"first_name":"Salvatore Maria","last_name":"Aglioti","domain_name":"independent","page_name":"SalvatoreMariaAglioti","display_name":"Salvatore Maria Aglioti","profile_url":"https://independent.academia.edu/SalvatoreMariaAglioti?f_ri=57557","photo":"https://0.academia-photos.com/31695561/9754801/10866996/s65_salvatore_maria.aglioti.jpg"}</script></span></span></li><li class="js-paper-rank-work_31330989 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="31330989"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 31330989, container: ".js-paper-rank-work_31330989", }); });</script></li><li class="js-percentile-work_31330989 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 31330989; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_31330989"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_31330989 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="31330989"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 31330989; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=31330989]").text(description); $(".js-view-count-work_31330989").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_31330989").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="31330989"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">17</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="237" rel="nofollow" href="https://www.academia.edu/Documents/in/Cognitive_Science">Cognitive Science</a>, <script data-card-contents-for-ri="237" type="text/json">{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="7736" rel="nofollow" href="https://www.academia.edu/Documents/in/Attention">Attention</a>, <script data-card-contents-for-ri="7736" type="text/json">{"id":7736,"name":"Attention","url":"https://www.academia.edu/Documents/in/Attention?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="41819" rel="nofollow" href="https://www.academia.edu/Documents/in/Brain_and_Cognition">Brain and Cognition</a><script data-card-contents-for-ri="41819" type="text/json">{"id":41819,"name":"Brain and Cognition","url":"https://www.academia.edu/Documents/in/Brain_and_Cognition?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=31330989]'), work: {"id":31330989,"title":"Influence of Stimulus Salience and Attentional Demands on Visual Search Patterns in Hemispatial Neglect","created_at":"2017-02-09T08:03:30.645-08:00","url":"https://www.academia.edu/31330989/Influence_of_Stimulus_Salience_and_Attentional_Demands_on_Visual_Search_Patterns_in_Hemispatial_Neglect?f_ri=57557","dom_id":"work_31330989","summary":"Seventy-five left and right brain-damaged patients, with or without hemispatial neglect, and 40 age-matched control subjects were tested on cancellation tasks with two different visual textures modeled after Julesz (1981). In one condition (''preattentive''), target elements segregated easily from background elements and were perceived effortlessly. In the other (''attentive''), target elements did not segregate easily and could be detected only after prolonged focal scrutiny. Both controls and patients were more accurate and faster on the preattentive than attentive texture. However, only neglect patients were disproportionately impaired on the attentive texture, thus suggesting that unilateral neglect is exacerbated by the low visual salience of the stimuli and a higher engagement of focal attention. Thus, a simple bedside test may help to tell apart the level of visual information processing maximally impaired in neglect patients.","downloadable_attachments":[{"id":51718146,"asset_id":31330989,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":31695561,"first_name":"Salvatore Maria","last_name":"Aglioti","domain_name":"independent","page_name":"SalvatoreMariaAglioti","display_name":"Salvatore Maria Aglioti","profile_url":"https://independent.academia.edu/SalvatoreMariaAglioti?f_ri=57557","photo":"https://0.academia-photos.com/31695561/9754801/10866996/s65_salvatore_maria.aglioti.jpg"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true},{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true},{"id":7736,"name":"Attention","url":"https://www.academia.edu/Documents/in/Attention?f_ri=57557","nofollow":true},{"id":41819,"name":"Brain and Cognition","url":"https://www.academia.edu/Documents/in/Brain_and_Cognition?f_ri=57557","nofollow":true},{"id":51533,"name":"Visual Search","url":"https://www.academia.edu/Documents/in/Visual_Search?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":66228,"name":"Thalamus","url":"https://www.academia.edu/Documents/in/Thalamus?f_ri=57557"},{"id":119665,"name":"Reaction Time","url":"https://www.academia.edu/Documents/in/Reaction_Time?f_ri=57557"},{"id":128285,"name":"Information Processing in Visual System","url":"https://www.academia.edu/Documents/in/Information_Processing_in_Visual_System?f_ri=57557"},{"id":406035,"name":"Unilateral Neglect","url":"https://www.academia.edu/Documents/in/Unilateral_Neglect?f_ri=57557"},{"id":406036,"name":"Parietal Lobe","url":"https://www.academia.edu/Documents/in/Parietal_Lobe?f_ri=57557"},{"id":413194,"name":"Analysis of Variance","url":"https://www.academia.edu/Documents/in/Analysis_of_Variance?f_ri=57557"},{"id":563992,"name":"Visual Fields","url":"https://www.academia.edu/Documents/in/Visual_Fields?f_ri=57557"},{"id":648349,"name":"Hemispatial Neglect","url":"https://www.academia.edu/Documents/in/Hemispatial_Neglect?f_ri=57557"},{"id":1205102,"name":"Cerebrovascular Disorders","url":"https://www.academia.edu/Documents/in/Cerebrovascular_Disorders?f_ri=57557"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=57557"},{"id":2234200,"name":"Functional Laterality","url":"https://www.academia.edu/Documents/in/Functional_Laterality?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_13181529" data-work_id="13181529" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13181529/Defining_the_broader_phenotype_of_autism_genetic_brain_and_behavioral_perspectives">Defining the broader phenotype of autism: genetic, brain, and behavioral perspectives</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Achieving progress in understanding the cause, nature, and treatment of autism requires an integration of concepts, approaches, and empirical findings from genetic, cognitive neuroscience, animal, and clinical studies. The need for such... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_13181529" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Achieving progress in understanding the cause, nature, and treatment of autism requires an integration of concepts, approaches, and empirical findings from genetic, cognitive neuroscience, animal, and clinical studies. The need for such integration has been a fundamental tenet of the discipline of developmental psychopathology from its inception. It is likely that the discovery of autism susceptibility genes will depend on the development of dimensional measures of broader phenotype autism traits. It is argued that knowledge of the cognitive neuroscience of social and language behavior will provide a useful framework for defining such measures. In this article, the current state of knowledge of the cognitive neuroscience of social and language impairments in autism is reviewed. Following from this, six candidate broader phenotype autism traits are proposed: (a) face processing, including structural encoding of facial features and face movements, such as eye gaze; (b) social affiliat...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13181529" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="bef1f0f6ae0ffbaa7ec1c6d48674f311" rel="nofollow" data-download="{"attachment_id":45611472,"asset_id":13181529,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45611472/download_file?st=MTc0MDE0MDM0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32438003" href="https://washington.academia.edu/SaraWebb">Sara Webb</a><script data-card-contents-for-user="32438003" type="text/json">{"id":32438003,"first_name":"Sara","last_name":"Webb","domain_name":"washington","page_name":"SaraWebb","display_name":"Sara Webb","profile_url":"https://washington.academia.edu/SaraWebb?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_13181529 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="13181529"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 13181529, container: ".js-paper-rank-work_13181529", }); 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The need for such integration has been a fundamental tenet of the discipline of developmental psychopathology from its inception. It is likely that the discovery of autism susceptibility genes will depend on the development of dimensional measures of broader phenotype autism traits. It is argued that knowledge of the cognitive neuroscience of social and language behavior will provide a useful framework for defining such measures. In this article, the current state of knowledge of the cognitive neuroscience of social and language impairments in autism is reviewed. Following from this, six candidate broader phenotype autism traits are proposed: (a) face processing, including structural encoding of facial features and face movements, such as eye gaze; (b) social affiliat...","downloadable_attachments":[{"id":45611472,"asset_id":13181529,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32438003,"first_name":"Sara","last_name":"Webb","domain_name":"washington","page_name":"SaraWebb","display_name":"Sara Webb","profile_url":"https://washington.academia.edu/SaraWebb?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":156,"name":"Genetics","url":"https://www.academia.edu/Documents/in/Genetics?f_ri=57557","nofollow":true},{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true},{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true},{"id":2139,"name":"Phonetics","url":"https://www.academia.edu/Documents/in/Phonetics?f_ri=57557","nofollow":true},{"id":5391,"name":"Speech perception","url":"https://www.academia.edu/Documents/in/Speech_perception?f_ri=57557"},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557"},{"id":20489,"name":"Phonological processing","url":"https://www.academia.edu/Documents/in/Phonological_processing?f_ri=57557"},{"id":21548,"name":"Cognitive Neuroscience","url":"https://www.academia.edu/Documents/in/Cognitive_Neuroscience?f_ri=57557"},{"id":23638,"name":"Specific Language Impairment","url":"https://www.academia.edu/Documents/in/Specific_Language_Impairment?f_ri=57557"},{"id":25060,"name":"Language Impairment","url":"https://www.academia.edu/Documents/in/Language_Impairment?f_ri=57557"},{"id":26067,"name":"Development","url":"https://www.academia.edu/Documents/in/Development?f_ri=57557"},{"id":28663,"name":"Language disorders","url":"https://www.academia.edu/Documents/in/Language_disorders?f_ri=57557"},{"id":33732,"name":"Executive Function","url":"https://www.academia.edu/Documents/in/Executive_Function?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain?f_ri=57557"},{"id":61516,"name":"Evoked Potentials","url":"https://www.academia.edu/Documents/in/Evoked_Potentials?f_ri=57557"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=57557"},{"id":100928,"name":"Face processing","url":"https://www.academia.edu/Documents/in/Face_processing?f_ri=57557"},{"id":119714,"name":"Facial Features","url":"https://www.academia.edu/Documents/in/Facial_Features?f_ri=57557"},{"id":213897,"name":"Phenotype","url":"https://www.academia.edu/Documents/in/Phenotype?f_ri=57557"},{"id":318779,"name":"Eye Gaze","url":"https://www.academia.edu/Documents/in/Eye_Gaze?f_ri=57557"},{"id":546356,"name":"Clinical Study","url":"https://www.academia.edu/Documents/in/Clinical_Study?f_ri=57557"},{"id":609835,"name":"Medial Temporal Lobe","url":"https://www.academia.edu/Documents/in/Medial_Temporal_Lobe?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_69254133" data-work_id="69254133" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/69254133/The_regulation_of_forebrain_dopamine_transmission_relevance_to_the_pathophysiology_and_psychopathology_of_schizophrenia">The regulation of forebrain dopamine transmission: relevance to the pathophysiology and psychopathology of schizophrenia</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Since the discovery that the therapeutic efficacy of antipsychotic drugs was significantly correlated to their ability to block dopamine D 2 receptors, abnormal dopamine transmission in the forebrain has been postulated to underlie... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_69254133" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Since the discovery that the therapeutic efficacy of antipsychotic drugs was significantly correlated to their ability to block dopamine D 2 receptors, abnormal dopamine transmission in the forebrain has been postulated to underlie psychosis in schizophrenia. In the past 15 years, an impressive amount of clinical and basic research aimed at the study of schizophrenia has indicated that prefrontal and temporal cortical abnormalities may be more important in the etiology of many of the symptoms of schizophrenia, including psychosis. However, the cortical systems that appear to have structural and/or metabolic abnormalities in schizophrenia patients potently regulate forebrain dopamine transmission through a number of mechanisms. In turn, dopamine modulates excitatory transmission mediated by frontal and temporal cortical projections to the basal ganglia and other regions. The present review summarizes the multiple interactions between forebrain DA systems and frontal and temporal corticostriatal transmission. It then examines the role of these interactions in normal behaviors and the psychopa</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/69254133" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="80da133ac73aeb3701a407414c84ae81" rel="nofollow" data-download="{"attachment_id":79419971,"asset_id":69254133,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/79419971/download_file?st=MTc0MDE0MDM0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="207329028" href="https://independent.academia.edu/HollyMoore33">Holly Moore</a><script data-card-contents-for-user="207329028" type="text/json">{"id":207329028,"first_name":"Holly","last_name":"Moore","domain_name":"independent","page_name":"HollyMoore33","display_name":"Holly Moore","profile_url":"https://independent.academia.edu/HollyMoore33?f_ri=57557","photo":"https://0.academia-photos.com/207329028/67559368/55927894/s65_holly.moore.png"}</script></span></span></li><li class="js-paper-rank-work_69254133 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="69254133"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 69254133, container: ".js-paper-rank-work_69254133", }); 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$(".js-view-count[data-work-id=69254133]").text(description); $(".js-view-count-work_69254133").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_69254133").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="69254133"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">17</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="3227" rel="nofollow" href="https://www.academia.edu/Documents/in/Schizophrenia">Schizophrenia</a>, <script data-card-contents-for-ri="3227" type="text/json">{"id":3227,"name":"Schizophrenia","url":"https://www.academia.edu/Documents/in/Schizophrenia?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="47884" rel="nofollow" href="https://www.academia.edu/Documents/in/Biological_Sciences">Biological Sciences</a><script data-card-contents-for-ri="47884" type="text/json">{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=69254133]'), work: {"id":69254133,"title":"The regulation of forebrain dopamine transmission: relevance to the pathophysiology and psychopathology of schizophrenia","created_at":"2022-01-23T07:32:03.556-08:00","url":"https://www.academia.edu/69254133/The_regulation_of_forebrain_dopamine_transmission_relevance_to_the_pathophysiology_and_psychopathology_of_schizophrenia?f_ri=57557","dom_id":"work_69254133","summary":"Since the discovery that the therapeutic efficacy of antipsychotic drugs was significantly correlated to their ability to block dopamine D 2 receptors, abnormal dopamine transmission in the forebrain has been postulated to underlie psychosis in schizophrenia. In the past 15 years, an impressive amount of clinical and basic research aimed at the study of schizophrenia has indicated that prefrontal and temporal cortical abnormalities may be more important in the etiology of many of the symptoms of schizophrenia, including psychosis. However, the cortical systems that appear to have structural and/or metabolic abnormalities in schizophrenia patients potently regulate forebrain dopamine transmission through a number of mechanisms. In turn, dopamine modulates excitatory transmission mediated by frontal and temporal cortical projections to the basal ganglia and other regions. The present review summarizes the multiple interactions between forebrain DA systems and frontal and temporal corticostriatal transmission. It then examines the role of these interactions in normal behaviors and the psychopa","downloadable_attachments":[{"id":79419971,"asset_id":69254133,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":207329028,"first_name":"Holly","last_name":"Moore","domain_name":"independent","page_name":"HollyMoore33","display_name":"Holly Moore","profile_url":"https://independent.academia.edu/HollyMoore33?f_ri=57557","photo":"https://0.academia-photos.com/207329028/67559368/55927894/s65_holly.moore.png"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true},{"id":3227,"name":"Schizophrenia","url":"https://www.academia.edu/Documents/in/Schizophrenia?f_ri=57557","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=57557","nofollow":true},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=57557","nofollow":true},{"id":49600,"name":"Biological Psychiatry","url":"https://www.academia.edu/Documents/in/Biological_Psychiatry?f_ri=57557"},{"id":51566,"name":"Dopamine","url":"https://www.academia.edu/Documents/in/Dopamine?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":61233,"name":"Glutamate","url":"https://www.academia.edu/Documents/in/Glutamate?f_ri=57557"},{"id":93922,"name":"Nitric oxide","url":"https://www.academia.edu/Documents/in/Nitric_oxide?f_ri=57557"},{"id":151951,"name":"Animal Model","url":"https://www.academia.edu/Documents/in/Animal_Model?f_ri=57557"},{"id":176503,"name":"Synaptic Transmission","url":"https://www.academia.edu/Documents/in/Synaptic_Transmission?f_ri=57557"},{"id":432613,"name":"Animal models","url":"https://www.academia.edu/Documents/in/Animal_models?f_ri=57557"},{"id":484219,"name":"Basal ganglia","url":"https://www.academia.edu/Documents/in/Basal_ganglia?f_ri=57557"},{"id":524508,"name":"Basic Research","url":"https://www.academia.edu/Documents/in/Basic_Research?f_ri=57557"},{"id":612870,"name":"Psychotic Disorders","url":"https://www.academia.edu/Documents/in/Psychotic_Disorders?f_ri=57557"},{"id":2922956,"name":"Psychology and Cognitive Sciences","url":"https://www.academia.edu/Documents/in/Psychology_and_Cognitive_Sciences?f_ri=57557"},{"id":3763225,"name":"Medical and Health Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_53714491" data-work_id="53714491" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/53714491/Anaplastic_pleomorphic_xanthoastrocytoma">Anaplastic pleomorphic xanthoastrocytoma</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">A case of anaplastic pleomorphic xanthoastrocytoma (PXA) in a 9-year-old girl is reported. Histological features of PXAs are cellular pleomorphism of GFAP-positive cells, with intracytoplasmic lipidic vacuoles and a reticulin network,... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_53714491" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">A case of anaplastic pleomorphic xanthoastrocytoma (PXA) in a 9-year-old girl is reported. Histological features of PXAs are cellular pleomorphism of GFAP-positive cells, with intracytoplasmic lipidic vacuoles and a reticulin network, bizarre giant cells, low mitotic activity, and lack of necrosis and of endothelial vascular proliferations. These tumors are generally reported to have a favorable postoperative course. In our case, a poor clinical prognosis and spread of the illness through the CSF was observed. Immunohistochemical features of the tumor, which were histologically anaplastic in nature, were analyzed. There were small foci of necrosis in the sections of the material obtained at the first operation and extensive necrosis in that from the second operation, although the patient had not received radiotherapy between the operations. The presence of necrosis in PXA is an uncommon and significant feature. It predicts the poor prognosis seen in this case, and therefore this report strongly supports the notion that necrosis should automatically exclude a tumor from the PXA category. The histological grade was evaluated as grade 3 (according to the WHO classification).</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/53714491" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="5a0ef29d01cddb88240015e1d7167b4d" rel="nofollow" data-download="{"attachment_id":70428584,"asset_id":53714491,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/70428584/download_file?st=MTc0MDE0MDM0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="191709153" href="https://independent.academia.edu/NaciBalak">Naci Balak</a><script data-card-contents-for-user="191709153" type="text/json">{"id":191709153,"first_name":"Naci","last_name":"Balak","domain_name":"independent","page_name":"NaciBalak","display_name":"Naci Balak","profile_url":"https://independent.academia.edu/NaciBalak?f_ri=57557","photo":"https://0.academia-photos.com/191709153/87120306/75795784/s65_naci.balak.jpeg"}</script></span></span></li><li class="js-paper-rank-work_53714491 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="53714491"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 53714491, container: ".js-paper-rank-work_53714491", }); 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$(".js-view-count[data-work-id=53714491]").text(description); $(".js-view-count-work_53714491").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_53714491").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="53714491"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">10</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="57557" rel="nofollow" href="https://www.academia.edu/Documents/in/Temporal_Lobe">Temporal Lobe</a>, <script data-card-contents-for-ri="57557" type="text/json">{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="64933" rel="nofollow" href="https://www.academia.edu/Documents/in/Child">Child</a>, <script data-card-contents-for-ri="64933" type="text/json">{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" rel="nofollow" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a>, <script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="448603" rel="nofollow" href="https://www.academia.edu/Documents/in/Necrosis">Necrosis</a><script data-card-contents-for-ri="448603" type="text/json">{"id":448603,"name":"Necrosis","url":"https://www.academia.edu/Documents/in/Necrosis?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=53714491]'), work: {"id":53714491,"title":"Anaplastic pleomorphic xanthoastrocytoma","created_at":"2021-09-28T06:57:35.114-07:00","url":"https://www.academia.edu/53714491/Anaplastic_pleomorphic_xanthoastrocytoma?f_ri=57557","dom_id":"work_53714491","summary":"A case of anaplastic pleomorphic xanthoastrocytoma (PXA) in a 9-year-old girl is reported. Histological features of PXAs are cellular pleomorphism of GFAP-positive cells, with intracytoplasmic lipidic vacuoles and a reticulin network, bizarre giant cells, low mitotic activity, and lack of necrosis and of endothelial vascular proliferations. These tumors are generally reported to have a favorable postoperative course. In our case, a poor clinical prognosis and spread of the illness through the CSF was observed. Immunohistochemical features of the tumor, which were histologically anaplastic in nature, were analyzed. There were small foci of necrosis in the sections of the material obtained at the first operation and extensive necrosis in that from the second operation, although the patient had not received radiotherapy between the operations. The presence of necrosis in PXA is an uncommon and significant feature. It predicts the poor prognosis seen in this case, and therefore this report strongly supports the notion that necrosis should automatically exclude a tumor from the PXA category. The histological grade was evaluated as grade 3 (according to the WHO classification).","downloadable_attachments":[{"id":70428584,"asset_id":53714491,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":191709153,"first_name":"Naci","last_name":"Balak","domain_name":"independent","page_name":"NaciBalak","display_name":"Naci Balak","profile_url":"https://independent.academia.edu/NaciBalak?f_ri=57557","photo":"https://0.academia-photos.com/191709153/87120306/75795784/s65_naci.balak.jpeg"}],"research_interests":[{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557","nofollow":true},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=57557","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=57557","nofollow":true},{"id":448603,"name":"Necrosis","url":"https://www.academia.edu/Documents/in/Necrosis?f_ri=57557","nofollow":true},{"id":485569,"name":"Glial Fibrillary Acidic Protein","url":"https://www.academia.edu/Documents/in/Glial_Fibrillary_Acidic_Protein?f_ri=57557"},{"id":489727,"name":"Prognosis","url":"https://www.academia.edu/Documents/in/Prognosis?f_ri=57557"},{"id":859051,"name":"Astrocytoma","url":"https://www.academia.edu/Documents/in/Astrocytoma?f_ri=57557"},{"id":959921,"name":"X ray Computed Tomography","url":"https://www.academia.edu/Documents/in/X_ray_Computed_Tomography?f_ri=57557"},{"id":1425045,"name":"Brain Neoplasms","url":"https://www.academia.edu/Documents/in/Brain_Neoplasms?f_ri=57557"},{"id":2482067,"name":"Reoperation","url":"https://www.academia.edu/Documents/in/Reoperation?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_13841835" data-work_id="13841835" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13841835/Convergent_Findings_for_Abnormalities_of_the_NF_%CE%BAB_Signaling_Pathway_in_Schizophrenia">Convergent Findings for Abnormalities of the NF-κB Signaling Pathway in Schizophrenia</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Neurons exhibit a constitutive level of nuclear factor-kB (NF-kB) signaling and this pathway plays a significant role in neurite outgrowth, activity-dependent plasticity, and cognitive function. Transcription factor analysis was performed... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_13841835" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Neurons exhibit a constitutive level of nuclear factor-kB (NF-kB) signaling and this pathway plays a significant role in neurite outgrowth, activity-dependent plasticity, and cognitive function. Transcription factor analysis was performed in a microarray data set profiled in four different brain regions (n ¼ 54 comparison group; n ¼ 53 schizophrenia (SZ)). An independent postmortem cohort was used for gene expression (n ¼ 24 comparison group; n ¼ 22 SZ), protein abundance (n ¼ 8 comparison group; n ¼ 8 SZ), and NF-kB nuclear activity (n ¼ 10 comparison group; n ¼ 10 SZ) quantification. Expression quantitative trait locus analysis was performed using publicly available data. Prepulse inhibition (PPI) of the acoustic startle reflex was tested in healthy individuals (n ¼ 690). Comparison of microarray data showed that NF-kB was among the transcription factors associated with the differential expression of genes in cases vs controls. NF-kB gene and protein levels and nuclear activation were significantly decreased in the superior temporal gyrus of patients with SZ. Upstream NF-kB genes related to translocation were significantly dysregulated in SZ. The gene expression levels of an NF-kB-associated importin (KPNA4: one of the proteins responsible for the translocation of NF-kB to the nucleus) was decreased in SZ and an SNP within the KPNA4 locus was associated with susceptibility to SZ, reduced KPNA4 expression levels and attenuated PPI of the startle reflex in healthy control subjects. These findings implicate abnormalities of the NF-kB signaling pathway in SZ and provide evidence for an additional possible mechanism affecting the translocation of NF-kB signaling to the nucleus.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13841835" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="1de5c69a5507b33258142752e37300af" rel="nofollow" data-download="{"attachment_id":44890713,"asset_id":13841835,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44890713/download_file?st=MTc0MDE0MDM0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32934189" href="https://mssm.academia.edu/PavelKatsel">Pavel Katsel</a><script data-card-contents-for-user="32934189" type="text/json">{"id":32934189,"first_name":"Pavel","last_name":"Katsel","domain_name":"mssm","page_name":"PavelKatsel","display_name":"Pavel Katsel","profile_url":"https://mssm.academia.edu/PavelKatsel?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_13841835 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="13841835"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 13841835, container: ".js-paper-rank-work_13841835", }); });</script></li><li class="js-percentile-work_13841835 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 13841835; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_13841835"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_13841835 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="13841835"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 13841835; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=13841835]").text(description); $(".js-view-count-work_13841835").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_13841835").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="13841835"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="3227" rel="nofollow" href="https://www.academia.edu/Documents/in/Schizophrenia">Schizophrenia</a>, <script data-card-contents-for-ri="3227" type="text/json">{"id":3227,"name":"Schizophrenia","url":"https://www.academia.edu/Documents/in/Schizophrenia?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="10115" rel="nofollow" href="https://www.academia.edu/Documents/in/Neuropsychopharmacology">Neuropsychopharmacology</a>, <script data-card-contents-for-ri="10115" type="text/json">{"id":10115,"name":"Neuropsychopharmacology","url":"https://www.academia.edu/Documents/in/Neuropsychopharmacology?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="38831" rel="nofollow" href="https://www.academia.edu/Documents/in/Signal_Transduction">Signal Transduction</a>, <script data-card-contents-for-ri="38831" type="text/json">{"id":38831,"name":"Signal Transduction","url":"https://www.academia.edu/Documents/in/Signal_Transduction?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="57557" rel="nofollow" href="https://www.academia.edu/Documents/in/Temporal_Lobe">Temporal Lobe</a><script data-card-contents-for-ri="57557" type="text/json">{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=13841835]'), work: {"id":13841835,"title":"Convergent Findings for Abnormalities of the NF-κB Signaling Pathway in Schizophrenia","created_at":"2015-07-09T08:18:55.942-07:00","url":"https://www.academia.edu/13841835/Convergent_Findings_for_Abnormalities_of_the_NF_%CE%BAB_Signaling_Pathway_in_Schizophrenia?f_ri=57557","dom_id":"work_13841835","summary":"Neurons exhibit a constitutive level of nuclear factor-kB (NF-kB) signaling and this pathway plays a significant role in neurite outgrowth, activity-dependent plasticity, and cognitive function. Transcription factor analysis was performed in a microarray data set profiled in four different brain regions (n ¼ 54 comparison group; n ¼ 53 schizophrenia (SZ)). An independent postmortem cohort was used for gene expression (n ¼ 24 comparison group; n ¼ 22 SZ), protein abundance (n ¼ 8 comparison group; n ¼ 8 SZ), and NF-kB nuclear activity (n ¼ 10 comparison group; n ¼ 10 SZ) quantification. Expression quantitative trait locus analysis was performed using publicly available data. Prepulse inhibition (PPI) of the acoustic startle reflex was tested in healthy individuals (n ¼ 690). Comparison of microarray data showed that NF-kB was among the transcription factors associated with the differential expression of genes in cases vs controls. NF-kB gene and protein levels and nuclear activation were significantly decreased in the superior temporal gyrus of patients with SZ. Upstream NF-kB genes related to translocation were significantly dysregulated in SZ. The gene expression levels of an NF-kB-associated importin (KPNA4: one of the proteins responsible for the translocation of NF-kB to the nucleus) was decreased in SZ and an SNP within the KPNA4 locus was associated with susceptibility to SZ, reduced KPNA4 expression levels and attenuated PPI of the startle reflex in healthy control subjects. These findings implicate abnormalities of the NF-kB signaling pathway in SZ and provide evidence for an additional possible mechanism affecting the translocation of NF-kB signaling to the nucleus.","downloadable_attachments":[{"id":44890713,"asset_id":13841835,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32934189,"first_name":"Pavel","last_name":"Katsel","domain_name":"mssm","page_name":"PavelKatsel","display_name":"Pavel Katsel","profile_url":"https://mssm.academia.edu/PavelKatsel?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":3227,"name":"Schizophrenia","url":"https://www.academia.edu/Documents/in/Schizophrenia?f_ri=57557","nofollow":true},{"id":10115,"name":"Neuropsychopharmacology","url":"https://www.academia.edu/Documents/in/Neuropsychopharmacology?f_ri=57557","nofollow":true},{"id":38831,"name":"Signal Transduction","url":"https://www.academia.edu/Documents/in/Signal_Transduction?f_ri=57557","nofollow":true},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557","nofollow":true},{"id":123418,"name":"NF-kappa B","url":"https://www.academia.edu/Documents/in/NF-kappa_B?f_ri=57557"},{"id":375054,"name":"Rats","url":"https://www.academia.edu/Documents/in/Rats?f_ri=57557"},{"id":704401,"name":"Neural pathways","url":"https://www.academia.edu/Documents/in/Neural_pathways?f_ri=57557"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=57557"},{"id":2039739,"name":"Down-Regulation","url":"https://www.academia.edu/Documents/in/Down-Regulation?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_14442587 coauthored" data-work_id="14442587" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/14442587/The_neural_correlates_of_recollection_Hippocampal_activation_declines_as_episodic_memory_fades">The neural correlates of recollection: Hippocampal activation declines as episodic memory fades</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Memories for certain events tend to linger in rich, vivid detail, and retrieval of these memories includes a sense of re-experiencing the details of the event. Most events, however, are not retained in any detailed way for more than a few... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_14442587" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Memories for certain events tend to linger in rich, vivid detail, and retrieval of these memories includes a sense of re-experiencing the details of the event. Most events, however, are not retained in any detailed way for more than a few days. According to one theory, the hippocampus plays a specific role in supporting episodic retrieval, that is, the re-experiencing of an event as part of one's personal past. This theory predicts that as episodic memories fade over time and are reduced to feelings of familiarity, activity in the hippocampus should no longer be associated with retrieval. We used high-resolution functional imaging to explore neural activity in medial temporal lobe subregions while participants performed a recognition task at both a short (10-min) and long (1-week) study-test delay. For each recognized item, subjects made ''Remember/Know'' judgments, allowing us to distinguish between items that were consistently episodic across the two tests and items that were initially episodic, but later became merely familiar. Our results demonstrate that activity in the subiculum is specifically associated with episodic recollection. Overall, recollected items were associated with higher activity in the subiculum than other items. For transiently recollected items, there was a decrease in subicular activity across the 1week delay as memory faded from recollection to familiarity, whereas consistently recollected items were associated with enhanced subicular activity at both delays. These results provide evidence of a link between subicular activation and recollective experience. V</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/14442587" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="7c3ca7fcd6f0db8e061cb8aea6db0dce" rel="nofollow" data-download="{"attachment_id":44144494,"asset_id":14442587,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44144494/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33380363" href="https://ucla.academia.edu/BarbaraKnowlton">Barbara Knowlton</a><script data-card-contents-for-user="33380363" type="text/json">{"id":33380363,"first_name":"Barbara","last_name":"Knowlton","domain_name":"ucla","page_name":"BarbaraKnowlton","display_name":"Barbara Knowlton","profile_url":"https://ucla.academia.edu/BarbaraKnowlton?f_ri=57557","photo":"https://0.academia-photos.com/33380363/9954623/11100580/s65_barbara.knowlton.jpg"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-14442587">+1</span><div class="hidden js-additional-users-14442587"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://usfca.academia.edu/IndreViskontas">Indre Viskontas</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-14442587'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-14442587').html(); 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Most events, however, are not retained in any detailed way for more than a few days. According to one theory, the hippocampus plays a specific role in supporting episodic retrieval, that is, the re-experiencing of an event as part of one's personal past. This theory predicts that as episodic memories fade over time and are reduced to feelings of familiarity, activity in the hippocampus should no longer be associated with retrieval. We used high-resolution functional imaging to explore neural activity in medial temporal lobe subregions while participants performed a recognition task at both a short (10-min) and long (1-week) study-test delay. For each recognized item, subjects made ''Remember/Know'' judgments, allowing us to distinguish between items that were consistently episodic across the two tests and items that were initially episodic, but later became merely familiar. Our results demonstrate that activity in the subiculum is specifically associated with episodic recollection. Overall, recollected items were associated with higher activity in the subiculum than other items. For transiently recollected items, there was a decrease in subicular activity across the 1week delay as memory faded from recollection to familiarity, whereas consistently recollected items were associated with enhanced subicular activity at both delays. These results provide evidence of a link between subicular activation and recollective experience. V","downloadable_attachments":[{"id":44144494,"asset_id":14442587,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33380363,"first_name":"Barbara","last_name":"Knowlton","domain_name":"ucla","page_name":"BarbaraKnowlton","display_name":"Barbara Knowlton","profile_url":"https://ucla.academia.edu/BarbaraKnowlton?f_ri=57557","photo":"https://0.academia-photos.com/33380363/9954623/11100580/s65_barbara.knowlton.jpg"},{"id":33435912,"first_name":"Indre","last_name":"Viskontas","domain_name":"usfca","page_name":"IndreViskontas","display_name":"Indre Viskontas","profile_url":"https://usfca.academia.edu/IndreViskontas?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":32361,"name":"Episodic Memory","url":"https://www.academia.edu/Documents/in/Episodic_Memory?f_ri=57557","nofollow":true},{"id":43773,"name":"Forgetting","url":"https://www.academia.edu/Documents/in/Forgetting?f_ri=57557","nofollow":true},{"id":57556,"name":"Hippocampus","url":"https://www.academia.edu/Documents/in/Hippocampus?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":100946,"name":"Functional Imaging","url":"https://www.academia.edu/Documents/in/Functional_Imaging?f_ri=57557"},{"id":309086,"name":"High Resolution","url":"https://www.academia.edu/Documents/in/High_Resolution?f_ri=57557"},{"id":357559,"name":"Remember-Know","url":"https://www.academia.edu/Documents/in/Remember-Know?f_ri=57557"},{"id":413194,"name":"Analysis of Variance","url":"https://www.academia.edu/Documents/in/Analysis_of_Variance?f_ri=57557"},{"id":522464,"name":"Short Term Memory","url":"https://www.academia.edu/Documents/in/Short_Term_Memory?f_ri=57557"},{"id":609835,"name":"Medial Temporal Lobe","url":"https://www.academia.edu/Documents/in/Medial_Temporal_Lobe?f_ri=57557"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_20153329" data-work_id="20153329" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/20153329/Impairment_of_language_is_related_to_left_parieto_temporal_glucose_metabolism_in_aphasic_stroke_patients">Impairment of language is related to left parieto-temporal glucose metabolism in aphasic stroke patients</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Twenty-six aphasic patients who had an ischaemic infarct in the territory of the left middle cerebral artery (MCA) were investigated. Cranial computed tomography (CT) showed various lesion sites: infarcts restricted to cortical structures... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_20153329" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Twenty-six aphasic patients who had an ischaemic infarct in the territory of the left middle cerebral artery (MCA) were investigated. Cranial computed tomography (CT) showed various lesion sites: infarcts restricted to cortical structures in 12 patients, combined eortical and subcortical infarcts in 7 and isolated subcortical infarcts sparing the left cortex in another 7 cases. 18F-2-fluoro-2-deoxyglucose positron emission tomography revealed remote hypometabolism of the left convexity cortex and of the left basal ganglia, which was extended further than the morphological infarct zone in all cases. Types and degrees of aphasia were classified using the Aachener Aphasie Test (AAT): 10 patients had global aphasia, 2 Broca's, 5 Wernicke's, and 5 amnesic aphasia. Four patients suffered from minimal or residual aphasic symptoms. The A A T results were compared with the regional cerebral metabolic rates of glucose of the left hemisphere, frrespective of the infarct location all five A A T subtests (Token test, repetition, written language, confrontation naming, äuditory and reading comprehension) were closely correlated among each other and with left parieto-temporal metabolic rates, whereas left frontal and left basal ganglia metabolism showed no significant correlation. The close relation between left temporo-parietal functional äctivity and alt five A A T subtests suggests that the different aspects of aphasia tested by A A T can be related to a common disorder of language processing in those areas.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/20153329" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="ff0e5da23dbc7535c2806eb4536c640b" rel="nofollow" data-download="{"attachment_id":41985184,"asset_id":20153329,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/41985184/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="41260332" href="https://independent.academia.edu/HKarbe">H. Karbe</a><script data-card-contents-for-user="41260332" type="text/json">{"id":41260332,"first_name":"H.","last_name":"Karbe","domain_name":"independent","page_name":"HKarbe","display_name":"H. 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Cranial computed tomography (CT) showed various lesion sites: infarcts restricted to cortical structures in 12 patients, combined eortical and subcortical infarcts in 7 and isolated subcortical infarcts sparing the left cortex in another 7 cases. 18F-2-fluoro-2-deoxyglucose positron emission tomography revealed remote hypometabolism of the left convexity cortex and of the left basal ganglia, which was extended further than the morphological infarct zone in all cases. Types and degrees of aphasia were classified using the Aachener Aphasie Test (AAT): 10 patients had global aphasia, 2 Broca's, 5 Wernicke's, and 5 amnesic aphasia. Four patients suffered from minimal or residual aphasic symptoms. The A A T results were compared with the regional cerebral metabolic rates of glucose of the left hemisphere, frrespective of the infarct location all five A A T subtests (Token test, repetition, written language, confrontation naming, äuditory and reading comprehension) were closely correlated among each other and with left parieto-temporal metabolic rates, whereas left frontal and left basal ganglia metabolism showed no significant correlation. The close relation between left temporo-parietal functional äctivity and alt five A A T subtests suggests that the different aspects of aphasia tested by A A T can be related to a common disorder of language processing in those areas.","downloadable_attachments":[{"id":41985184,"asset_id":20153329,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":41260332,"first_name":"H.","last_name":"Karbe","domain_name":"independent","page_name":"HKarbe","display_name":"H. Karbe","profile_url":"https://independent.academia.edu/HKarbe?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":623,"name":"Neurology","url":"https://www.academia.edu/Documents/in/Neurology?f_ri=57557","nofollow":true},{"id":1648,"name":"Computed Tomography","url":"https://www.academia.edu/Documents/in/Computed_Tomography?f_ri=57557","nofollow":true},{"id":5738,"name":"Aphasia","url":"https://www.academia.edu/Documents/in/Aphasia?f_ri=57557","nofollow":true},{"id":14180,"name":"Reading Comprehension","url":"https://www.academia.edu/Documents/in/Reading_Comprehension?f_ri=57557","nofollow":true},{"id":23518,"name":"Positron Emission Tomography","url":"https://www.academia.edu/Documents/in/Positron_Emission_Tomography?f_ri=57557"},{"id":28663,"name":"Language disorders","url":"https://www.academia.edu/Documents/in/Language_disorders?f_ri=57557"},{"id":33890,"name":"Language Processing","url":"https://www.academia.edu/Documents/in/Language_Processing?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":71289,"name":"Glucose","url":"https://www.academia.edu/Documents/in/Glucose?f_ri=57557"},{"id":71431,"name":"Glucose Metabolism","url":"https://www.academia.edu/Documents/in/Glucose_Metabolism?f_ri=57557"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=57557"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=57557"},{"id":296766,"name":"Metabolic rate","url":"https://www.academia.edu/Documents/in/Metabolic_rate?f_ri=57557"},{"id":375439,"name":"Single Photon Emission Computed Tomography","url":"https://www.academia.edu/Documents/in/Single_Photon_Emission_Computed_Tomography?f_ri=57557"},{"id":406036,"name":"Parietal Lobe","url":"https://www.academia.edu/Documents/in/Parietal_Lobe?f_ri=57557"},{"id":484219,"name":"Basal ganglia","url":"https://www.academia.edu/Documents/in/Basal_ganglia?f_ri=57557"},{"id":810789,"name":"Left Hemisphere","url":"https://www.academia.edu/Documents/in/Left_Hemisphere?f_ri=57557"},{"id":1205102,"name":"Cerebrovascular Disorders","url":"https://www.academia.edu/Documents/in/Cerebrovascular_Disorders?f_ri=57557"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=57557"},{"id":1453325,"name":"Middle Cerebral Artery","url":"https://www.academia.edu/Documents/in/Middle_Cerebral_Artery?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_18984685" data-work_id="18984685" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/18984685/Assessing_mental_flexibility_neuroanatomical_and_neuropsychological_correlates_of_the_trail_making_test_in_elderly_people">Assessing mental flexibility: neuroanatomical and neuropsychological correlates of the trail making test in elderly people</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/18984685" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="0bc3ed8ab8811298968955f6808127fe" rel="nofollow" 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{"id":18984685,"title":"Assessing mental flexibility: neuroanatomical and neuropsychological correlates of the trail making test in elderly people","created_at":"2015-11-25T06:14:25.587-08:00","url":"https://www.academia.edu/18984685/Assessing_mental_flexibility_neuroanatomical_and_neuropsychological_correlates_of_the_trail_making_test_in_elderly_people?f_ri=57557","dom_id":"work_18984685","summary":null,"downloadable_attachments":[{"id":40366631,"asset_id":18984685,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":39133573,"first_name":"Joukje","last_name":"Oosterman","domain_name":"independent","page_name":"JoukjeOosterman","display_name":"Joukje Oosterman","profile_url":"https://independent.academia.edu/JoukjeOosterman?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true},{"id":237,"name":"Cognitive 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tests","url":"https://www.academia.edu/Documents/in/Predictive_value_of_tests?f_ri=57557"},{"id":1627527,"name":"Cognition disorders","url":"https://www.academia.edu/Documents/in/Cognition_disorders?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_18218598" data-work_id="18218598" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/18218598/Neural_correlates_of_category_specific_knowledge">Neural correlates of category-specific knowledge</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" 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Lobe","url":"https://www.academia.edu/Documents/in/Frontal_Lobe?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_29458896" data-work_id="29458896" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/29458896/Frontal_lobe_degeneration_of_non_Alzheimer_type_III_Regional_cerebral_blood_flow">Frontal lobe degeneration of non-Alzheimer type. III. Regional cerebral blood flow?</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">In a longitudinal prospective study of dementia, 158 patients were investigated post mortem. Sixteen patients were classified as frontal lobe dementia (FLD) of non-Alzheimer type and four cases as Pick's disease. Positive heredity for... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_29458896" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">In a longitudinal prospective study of dementia, 158 patients were investigated post mortem. Sixteen patients were classified as frontal lobe dementia (FLD) of non-Alzheimer type and four cases as Pick's disease. Positive heredity for dementia was reported in 50% of these cases compared to 30% in a reference group of patients with Alzheimer's disease (AD). The typical clinical picture in FLD and Pick's disease was that of a slowly progressive dementia, at an early stage dominated by personality change, lack of insight, disinhibition, and later on stereotypy and increased apathy. There was also a progressive dynamic aphasia ending in mutism and amimia. Memory and spatial functions were comparatively spared. Disinhibition, oral/dietary hyperactivity, and echolalia were more consistently found in Pick's disease compared to FLD. The differential diagnosis against AD, cerebrovascular dementia, and other degenerative dementias and against affective disorders and psychotic reactions are discussed.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/29458896" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="45e4eb234e7377d28c46e038dde4d0f6" rel="nofollow" data-download="{"attachment_id":49903454,"asset_id":29458896,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/49903454/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="48845082" href="https://independent.academia.edu/JarlRisberg">Jarl Risberg</a><script data-card-contents-for-user="48845082" type="text/json">{"id":48845082,"first_name":"Jarl","last_name":"Risberg","domain_name":"independent","page_name":"JarlRisberg","display_name":"Jarl Risberg","profile_url":"https://independent.academia.edu/JarlRisberg?f_ri=57557","photo":"https://0.academia-photos.com/48845082/70964016/59397641/s65_jarl.risberg.jpg"}</script></span></span></li><li class="js-paper-rank-work_29458896 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="29458896"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 29458896, container: ".js-paper-rank-work_29458896", }); 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$(".js-view-count[data-work-id=29458896]").text(description); $(".js-view-count-work_29458896").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_29458896").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="29458896"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">20</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="3662" rel="nofollow" href="https://www.academia.edu/Documents/in/Dementia">Dementia</a>, <script data-card-contents-for-ri="3662" type="text/json">{"id":3662,"name":"Dementia","url":"https://www.academia.edu/Documents/in/Dementia?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="5738" rel="nofollow" href="https://www.academia.edu/Documents/in/Aphasia">Aphasia</a>, <script data-card-contents-for-ri="5738" type="text/json">{"id":5738,"name":"Aphasia","url":"https://www.academia.edu/Documents/in/Aphasia?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="28663" rel="nofollow" href="https://www.academia.edu/Documents/in/Language_disorders">Language disorders</a><script data-card-contents-for-ri="28663" type="text/json">{"id":28663,"name":"Language disorders","url":"https://www.academia.edu/Documents/in/Language_disorders?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=29458896]'), work: {"id":29458896,"title":"Frontal lobe degeneration of non-Alzheimer type. III. Regional cerebral blood flow?","created_at":"2016-10-27T00:52:34.572-07:00","url":"https://www.academia.edu/29458896/Frontal_lobe_degeneration_of_non_Alzheimer_type_III_Regional_cerebral_blood_flow?f_ri=57557","dom_id":"work_29458896","summary":"In a longitudinal prospective study of dementia, 158 patients were investigated post mortem. Sixteen patients were classified as frontal lobe dementia (FLD) of non-Alzheimer type and four cases as Pick's disease. Positive heredity for dementia was reported in 50% of these cases compared to 30% in a reference group of patients with Alzheimer's disease (AD). The typical clinical picture in FLD and Pick's disease was that of a slowly progressive dementia, at an early stage dominated by personality change, lack of insight, disinhibition, and later on stereotypy and increased apathy. There was also a progressive dynamic aphasia ending in mutism and amimia. Memory and spatial functions were comparatively spared. Disinhibition, oral/dietary hyperactivity, and echolalia were more consistently found in Pick's disease compared to FLD. The differential diagnosis against AD, cerebrovascular dementia, and other degenerative dementias and against affective disorders and psychotic reactions are discussed.","downloadable_attachments":[{"id":49903454,"asset_id":29458896,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":48845082,"first_name":"Jarl","last_name":"Risberg","domain_name":"independent","page_name":"JarlRisberg","display_name":"Jarl Risberg","profile_url":"https://independent.academia.edu/JarlRisberg?f_ri=57557","photo":"https://0.academia-photos.com/48845082/70964016/59397641/s65_jarl.risberg.jpg"}],"research_interests":[{"id":3662,"name":"Dementia","url":"https://www.academia.edu/Documents/in/Dementia?f_ri=57557","nofollow":true},{"id":5738,"name":"Aphasia","url":"https://www.academia.edu/Documents/in/Aphasia?f_ri=57557","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":28663,"name":"Language disorders","url":"https://www.academia.edu/Documents/in/Language_disorders?f_ri=57557","nofollow":true},{"id":42973,"name":"Amyotrophic Lateral Sclerosis","url":"https://www.academia.edu/Documents/in/Amyotrophic_Lateral_Sclerosis?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":78467,"name":"Cerebral Cortex","url":"https://www.academia.edu/Documents/in/Cerebral_Cortex?f_ri=57557"},{"id":162159,"name":"Differential Diagnosis","url":"https://www.academia.edu/Documents/in/Differential_Diagnosis?f_ri=57557"},{"id":188349,"name":"Pedigree","url":"https://www.academia.edu/Documents/in/Pedigree?f_ri=57557"},{"id":193974,"name":"Neurons","url":"https://www.academia.edu/Documents/in/Neurons?f_ri=57557"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=57557"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=57557"},{"id":330953,"name":"Longitudinal Studies","url":"https://www.academia.edu/Documents/in/Longitudinal_Studies?f_ri=57557"},{"id":361229,"name":"Alzheimer Dementia","url":"https://www.academia.edu/Documents/in/Alzheimer_Dementia?f_ri=57557"},{"id":436755,"name":"Degeneration","url":"https://www.academia.edu/Documents/in/Degeneration?f_ri=57557"},{"id":959921,"name":"X ray Computed Tomography","url":"https://www.academia.edu/Documents/in/X_ray_Computed_Tomography?f_ri=57557"},{"id":1120234,"name":"Alzheimer Disease","url":"https://www.academia.edu/Documents/in/Alzheimer_Disease?f_ri=57557"},{"id":1257483,"name":"Frontal Lobe","url":"https://www.academia.edu/Documents/in/Frontal_Lobe?f_ri=57557"},{"id":1627527,"name":"Cognition disorders","url":"https://www.academia.edu/Documents/in/Cognition_disorders?f_ri=57557"},{"id":2186336,"name":"Gliosis","url":"https://www.academia.edu/Documents/in/Gliosis?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_5367460" data-work_id="5367460" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/5367460/Towards_understanding_of_the_cortical_network_underlying_associative_memory">Towards understanding of the cortical network underlying associative memory</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Declarative knowledge and experiences are represented in the association cortex and are recalled by reactivation of the neural representation. Electrophysiological experiments have revealed that associations between semantically linked... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_5367460" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Declarative knowledge and experiences are represented in the association cortex and are recalled by reactivation of the neural representation. Electrophysiological experiments have revealed that associations between semantically linked visual objects are formed in neural representations in the temporal and limbic cortices. Memory traces are created by the reorganization of neural circuits. These regions are reactivated during retrieval and contribute to the contents of a memory. Two different types of retrieval signals are suggested as follows: automatic and active. One flows backward from the medial temporal lobe during the automatic retrieval process, whereas the other is conveyed as a top-down signal from the prefrontal cortex to the temporal cortex during the active retrieval process. By sending the top-down signal, the prefrontal cortex manipulates and organizes to-be-remembered information, devises strategies for retrieval and monitors the outcome. To further understand the neural mechanism of memory, the following two complementary views are needed: how the multiple cortical areas in the brain-wide network interact to orchestrate cognitive functions and how the properties of single neurons and their synaptic connections with neighbouring neurons combine to form local circuits and to exhibit the function of each cortical area. We will discuss some new methodological innovations that tackle these challenges.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/5367460" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="2f082ae7d280b9e49605898653542026" rel="nofollow" data-download="{"attachment_id":49323875,"asset_id":5367460,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/49323875/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="7463833" href="https://u-tokyo.academia.edu/YusukeAdachi">Yusuke Adachi</a><script data-card-contents-for-user="7463833" type="text/json">{"id":7463833,"first_name":"Yusuke","last_name":"Adachi","domain_name":"u-tokyo","page_name":"YusukeAdachi","display_name":"Yusuke Adachi","profile_url":"https://u-tokyo.academia.edu/YusukeAdachi?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_5367460 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="5367460"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 5367460, container: ".js-paper-rank-work_5367460", }); });</script></li><li class="js-percentile-work_5367460 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 5367460; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_5367460"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_5367460 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="5367460"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 5367460; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=5367460]").text(description); $(".js-view-count-work_5367460").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_5367460").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="5367460"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">7</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="28576" rel="nofollow" href="https://www.academia.edu/Documents/in/Prefrontal_Cortex">Prefrontal Cortex</a>, <script data-card-contents-for-ri="28576" type="text/json">{"id":28576,"name":"Prefrontal Cortex","url":"https://www.academia.edu/Documents/in/Prefrontal_Cortex?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="46858" rel="nofollow" href="https://www.academia.edu/Documents/in/Memory">Memory</a>, <script data-card-contents-for-ri="46858" type="text/json">{"id":46858,"name":"Memory","url":"https://www.academia.edu/Documents/in/Memory?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="47884" rel="nofollow" href="https://www.academia.edu/Documents/in/Biological_Sciences">Biological Sciences</a><script data-card-contents-for-ri="47884" type="text/json">{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=5367460]'), work: {"id":5367460,"title":"Towards understanding of the cortical network underlying associative memory","created_at":"2013-12-09T11:38:28.883-08:00","url":"https://www.academia.edu/5367460/Towards_understanding_of_the_cortical_network_underlying_associative_memory?f_ri=57557","dom_id":"work_5367460","summary":"Declarative knowledge and experiences are represented in the association cortex and are recalled by reactivation of the neural representation. Electrophysiological experiments have revealed that associations between semantically linked visual objects are formed in neural representations in the temporal and limbic cortices. Memory traces are created by the reorganization of neural circuits. These regions are reactivated during retrieval and contribute to the contents of a memory. Two different types of retrieval signals are suggested as follows: automatic and active. One flows backward from the medial temporal lobe during the automatic retrieval process, whereas the other is conveyed as a top-down signal from the prefrontal cortex to the temporal cortex during the active retrieval process. By sending the top-down signal, the prefrontal cortex manipulates and organizes to-be-remembered information, devises strategies for retrieval and monitors the outcome. To further understand the neural mechanism of memory, the following two complementary views are needed: how the multiple cortical areas in the brain-wide network interact to orchestrate cognitive functions and how the properties of single neurons and their synaptic connections with neighbouring neurons combine to form local circuits and to exhibit the function of each cortical area. We will discuss some new methodological innovations that tackle these challenges.","downloadable_attachments":[{"id":49323875,"asset_id":5367460,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":7463833,"first_name":"Yusuke","last_name":"Adachi","domain_name":"u-tokyo","page_name":"YusukeAdachi","display_name":"Yusuke Adachi","profile_url":"https://u-tokyo.academia.edu/YusukeAdachi?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":28576,"name":"Prefrontal Cortex","url":"https://www.academia.edu/Documents/in/Prefrontal_Cortex?f_ri=57557","nofollow":true},{"id":46858,"name":"Memory","url":"https://www.academia.edu/Documents/in/Memory?f_ri=57557","nofollow":true},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=57557","nofollow":true},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":328150,"name":"Associative Memory","url":"https://www.academia.edu/Documents/in/Associative_Memory?f_ri=57557"},{"id":704401,"name":"Neural pathways","url":"https://www.academia.edu/Documents/in/Neural_pathways?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_5512330" data-work_id="5512330" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/5512330/Neural_correlates_of_humor_detection_and_appreciation">Neural correlates of humor detection and appreciation</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Humor is a uniquely human quality whose neural substrates remain enigmatic. The present report combined dynamic, real-life content and event-related functional magnetic resonance imaging (fMRI) to dissociate humor detection (''getting the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_5512330" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Humor is a uniquely human quality whose neural substrates remain enigmatic. The present report combined dynamic, real-life content and event-related functional magnetic resonance imaging (fMRI) to dissociate humor detection (''getting the joke'') from humor appreciation (the affective experience of mirth). During scanning, subjects viewed full-length episodes of the television sitcoms Seinfeld or The Simpsons. Brain activity time-locked to humor detection moments revealed increases in left inferior frontal and posterior temporal cortices, whereas brain activity time-locked to moments of humor appreciation revealed increases in bilateral regions of insular cortex and the amygdala. These findings provide evidence that humor depends critically upon extant neural systems important for resolving incongruities (humor detection) and for the expression of affect (humor appreciation).</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/5512330" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="4f84f8da017a1f4dc3bdaaf51213afd7" rel="nofollow" data-download="{"attachment_id":49263574,"asset_id":5512330,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/49263574/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="7784477" href="https://utdallas.academia.edu/GaganWig">Gagan Wig</a><script data-card-contents-for-user="7784477" type="text/json">{"id":7784477,"first_name":"Gagan","last_name":"Wig","domain_name":"utdallas","page_name":"GaganWig","display_name":"Gagan Wig","profile_url":"https://utdallas.academia.edu/GaganWig?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_5512330 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="5512330"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 5512330, container: ".js-paper-rank-work_5512330", }); });</script></li><li class="js-percentile-work_5512330 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 5512330; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_5512330"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_5512330 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="5512330"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 5512330; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=5512330]").text(description); $(".js-view-count-work_5512330").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_5512330").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="5512330"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">21</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="161" rel="nofollow" href="https://www.academia.edu/Documents/in/Neuroscience">Neuroscience</a>, <script data-card-contents-for-ri="161" type="text/json">{"id":161,"name":"Neuroscience","url":"https://www.academia.edu/Documents/in/Neuroscience?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4626" rel="nofollow" href="https://www.academia.edu/Documents/in/Social_Cognition">Social Cognition</a>, <script data-card-contents-for-ri="4626" type="text/json">{"id":4626,"name":"Social Cognition","url":"https://www.academia.edu/Documents/in/Social_Cognition?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a><script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=5512330]'), work: {"id":5512330,"title":"Neural correlates of humor detection and appreciation","created_at":"2013-12-23T09:48:08.862-08:00","url":"https://www.academia.edu/5512330/Neural_correlates_of_humor_detection_and_appreciation?f_ri=57557","dom_id":"work_5512330","summary":"Humor is a uniquely human quality whose neural substrates remain enigmatic. The present report combined dynamic, real-life content and event-related functional magnetic resonance imaging (fMRI) to dissociate humor detection (''getting the joke'') from humor appreciation (the affective experience of mirth). During scanning, subjects viewed full-length episodes of the television sitcoms Seinfeld or The Simpsons. Brain activity time-locked to humor detection moments revealed increases in left inferior frontal and posterior temporal cortices, whereas brain activity time-locked to moments of humor appreciation revealed increases in bilateral regions of insular cortex and the amygdala. These findings provide evidence that humor depends critically upon extant neural systems important for resolving incongruities (humor detection) and for the expression of affect (humor appreciation).","downloadable_attachments":[{"id":49263574,"asset_id":5512330,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":7784477,"first_name":"Gagan","last_name":"Wig","domain_name":"utdallas","page_name":"GaganWig","display_name":"Gagan Wig","profile_url":"https://utdallas.academia.edu/GaganWig?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":161,"name":"Neuroscience","url":"https://www.academia.edu/Documents/in/Neuroscience?f_ri=57557","nofollow":true},{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true},{"id":4626,"name":"Social Cognition","url":"https://www.academia.edu/Documents/in/Social_Cognition?f_ri=57557","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":32913,"name":"Neuroimmunology","url":"https://www.academia.edu/Documents/in/Neuroimmunology?f_ri=57557"},{"id":42162,"name":"Emotions","url":"https://www.academia.edu/Documents/in/Emotions?f_ri=57557"},{"id":52176,"name":"Brain Mapping","url":"https://www.academia.edu/Documents/in/Brain_Mapping?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain?f_ri=57557"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=57557"},{"id":103260,"name":"Neuroimage","url":"https://www.academia.edu/Documents/in/Neuroimage?f_ri=57557"},{"id":119665,"name":"Reaction Time","url":"https://www.academia.edu/Documents/in/Reaction_Time?f_ri=57557"},{"id":161176,"name":"The","url":"https://www.academia.edu/Documents/in/The?f_ri=57557"},{"id":329042,"name":"Head Movements","url":"https://www.academia.edu/Documents/in/Head_Movements?f_ri=57557"},{"id":406036,"name":"Parietal Lobe","url":"https://www.academia.edu/Documents/in/Parietal_Lobe?f_ri=57557"},{"id":468209,"name":"Videotape Recording","url":"https://www.academia.edu/Documents/in/Videotape_Recording?f_ri=57557"},{"id":546419,"name":"Age Factors","url":"https://www.academia.edu/Documents/in/Age_Factors?f_ri=57557"},{"id":589319,"name":"Insular Cortex","url":"https://www.academia.edu/Documents/in/Insular_Cortex?f_ri=57557"},{"id":945595,"name":"Pilot Projects","url":"https://www.academia.edu/Documents/in/Pilot_Projects?f_ri=57557"},{"id":1556410,"name":"Full Length Movies","url":"https://www.academia.edu/Documents/in/Full_Length_Movies?f_ri=57557"},{"id":2234200,"name":"Functional Laterality","url":"https://www.academia.edu/Documents/in/Functional_Laterality?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_11869144" data-work_id="11869144" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/11869144/Visual_spatial_working_memory_performance_and_temporal_gray_matter_volume_predict_schizotypal_personality_disorder_group_membership">Visual–spatial working memory performance and temporal gray matter volume predict schizotypal personality disorder group membership</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Background: Prior work shows individuals with schizotypal personality disorder (SPD) evince temporal lobe volume abnormalities similar to schizophrenia but sparing of prefrontal cortex, which may mitigate psychosis and the severe... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_11869144" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Background: Prior work shows individuals with schizotypal personality disorder (SPD) evince temporal lobe volume abnormalities similar to schizophrenia but sparing of prefrontal cortex, which may mitigate psychosis and the severe neurocognitive impairments observed in schizophrenia. This study examined the extent to which frontal-temporal gray matter volume and neurocognitive performance predict: (1) SPD group membership in a demographically-balanced sample of 51 patients and 37 healthy controls; and (2) symptom severity in SPD. Methods: Dimensional gray-matter volume (left frontal-temporal regions (Brodmann area (BA) 10, 21, 22)) and neurocognitive performance on key memory tasks (California Verbal Learning Test (CVLT), Dot Test, Paced Auditory Serial Addition Test (PASAT)), all salient to schizophrenia-spectrum disorders were examined in a multi-variable model. Results: Middle temporal gyrus (BA21) volume and spatial-working memory (Dot Test) performance were significant predictors of SPD group membership likelihood, with poorer working-memory performance indicating increased probability of SPD membership. Combining across regional volumes or cognitive measures resulted in fair-to-good discrimination of group membership, but including neurocognitive and non-collinear regional volume measures together resulted in a receiver-operating-characteristic (ROC) curve with improved diagnostic discrimination. Larger BA10 volume in dorsolateral prefrontal cortex (DLPFC) significantly predicted less symptom severity in SPD. Conclusions: These findings suggest that temporal lobe volume and spatial-working memory performance are promising biological/phenotype markers for likelihood of SPD classification, while greater DLPFC volume may serve as a protective factor.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/11869144" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="548225844bbadae057a8b56a55b40ed7" rel="nofollow" data-download="{"attachment_id":46474831,"asset_id":11869144,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46474831/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="29320646" href="https://independent.academia.edu/LarrySiever">Larry Siever</a><script data-card-contents-for-user="29320646" type="text/json">{"id":29320646,"first_name":"Larry","last_name":"Siever","domain_name":"independent","page_name":"LarrySiever","display_name":"Larry Siever","profile_url":"https://independent.academia.edu/LarrySiever?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_11869144 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="11869144"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 11869144, container: ".js-paper-rank-work_11869144", }); });</script></li><li class="js-percentile-work_11869144 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 11869144; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_11869144"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_11869144 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="11869144"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 11869144; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=11869144]").text(description); $(".js-view-count-work_11869144").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_11869144").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="11869144"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">12</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="3227" rel="nofollow" href="https://www.academia.edu/Documents/in/Schizophrenia">Schizophrenia</a>, <script data-card-contents-for-ri="3227" type="text/json">{"id":3227,"name":"Schizophrenia","url":"https://www.academia.edu/Documents/in/Schizophrenia?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="8538" rel="nofollow" href="https://www.academia.edu/Documents/in/Working_Memory">Working Memory</a>, <script data-card-contents-for-ri="8538" type="text/json">{"id":8538,"name":"Working Memory","url":"https://www.academia.edu/Documents/in/Working_Memory?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="41482" rel="nofollow" href="https://www.academia.edu/Documents/in/Multivariate_Analysis">Multivariate Analysis</a><script data-card-contents-for-ri="41482" type="text/json">{"id":41482,"name":"Multivariate Analysis","url":"https://www.academia.edu/Documents/in/Multivariate_Analysis?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=11869144]'), work: {"id":11869144,"title":"Visual–spatial working memory performance and temporal gray matter volume predict schizotypal personality disorder group membership","created_at":"2015-04-09T09:20:54.055-07:00","url":"https://www.academia.edu/11869144/Visual_spatial_working_memory_performance_and_temporal_gray_matter_volume_predict_schizotypal_personality_disorder_group_membership?f_ri=57557","dom_id":"work_11869144","summary":"Background: Prior work shows individuals with schizotypal personality disorder (SPD) evince temporal lobe volume abnormalities similar to schizophrenia but sparing of prefrontal cortex, which may mitigate psychosis and the severe neurocognitive impairments observed in schizophrenia. This study examined the extent to which frontal-temporal gray matter volume and neurocognitive performance predict: (1) SPD group membership in a demographically-balanced sample of 51 patients and 37 healthy controls; and (2) symptom severity in SPD. Methods: Dimensional gray-matter volume (left frontal-temporal regions (Brodmann area (BA) 10, 21, 22)) and neurocognitive performance on key memory tasks (California Verbal Learning Test (CVLT), Dot Test, Paced Auditory Serial Addition Test (PASAT)), all salient to schizophrenia-spectrum disorders were examined in a multi-variable model. Results: Middle temporal gyrus (BA21) volume and spatial-working memory (Dot Test) performance were significant predictors of SPD group membership likelihood, with poorer working-memory performance indicating increased probability of SPD membership. Combining across regional volumes or cognitive measures resulted in fair-to-good discrimination of group membership, but including neurocognitive and non-collinear regional volume measures together resulted in a receiver-operating-characteristic (ROC) curve with improved diagnostic discrimination. Larger BA10 volume in dorsolateral prefrontal cortex (DLPFC) significantly predicted less symptom severity in SPD. Conclusions: These findings suggest that temporal lobe volume and spatial-working memory performance are promising biological/phenotype markers for likelihood of SPD classification, while greater DLPFC volume may serve as a protective factor.","downloadable_attachments":[{"id":46474831,"asset_id":11869144,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":29320646,"first_name":"Larry","last_name":"Siever","domain_name":"independent","page_name":"LarrySiever","display_name":"Larry Siever","profile_url":"https://independent.academia.edu/LarrySiever?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":3227,"name":"Schizophrenia","url":"https://www.academia.edu/Documents/in/Schizophrenia?f_ri=57557","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":8538,"name":"Working Memory","url":"https://www.academia.edu/Documents/in/Working_Memory?f_ri=57557","nofollow":true},{"id":41482,"name":"Multivariate Analysis","url":"https://www.academia.edu/Documents/in/Multivariate_Analysis?f_ri=57557","nofollow":true},{"id":45349,"name":"Space perception","url":"https://www.academia.edu/Documents/in/Space_perception?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":60558,"name":"Neurocognition","url":"https://www.academia.edu/Documents/in/Neurocognition?f_ri=57557"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=57557"},{"id":282100,"name":"Schizotypal Personality Disorder","url":"https://www.academia.edu/Documents/in/Schizotypal_Personality_Disorder?f_ri=57557"},{"id":522464,"name":"Short Term Memory","url":"https://www.academia.edu/Documents/in/Short_Term_Memory?f_ri=57557"},{"id":974411,"name":"Memory Disorders","url":"https://www.academia.edu/Documents/in/Memory_Disorders?f_ri=57557"},{"id":2467548,"name":"Neuropsychological Tests","url":"https://www.academia.edu/Documents/in/Neuropsychological_Tests?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_25928380" data-work_id="25928380" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/25928380/Therapy_induced_brain_reorganization_patterns_in_aphasia">Therapy-induced brain reorganization patterns in aphasia</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Both hemispheres are engaged in recovery from word production deficits in aphasia. Lexical therapy has been shown to induce brain reorganization even in patients with chronic aphasia. However, the interplay of factors influencing... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_25928380" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Both hemispheres are engaged in recovery from word production deficits in aphasia. Lexical therapy has been shown to induce brain reorganization even in patients with chronic aphasia. However, the interplay of factors influencing reorganization patterns still remains unresolved. We were especially interested in the relation between lesion site, therapy-induced recovery, and beneficial reorganization patterns. Thus, we applied intensive lexical therapy, which was evaluated with functional magnetic resonance imaging, to 14 chronic patients with aphasic word retrieval deficits. In a group study, we aimed to illuminate brain reorganization of the naming network in comparison with healthy controls. Moreover, we intended to analyse the data with joint independent component analysis to relate lesion sites to therapy-induced brain reorganization, and to correlate resulting components with therapy gain. As a result, we found peri-lesional and contralateral activations basically overlapping with premorbid naming networks observed in healthy subjects. Reduced activation patterns for patients compared to controls before training comprised damaged left hemisphere language areas, right precentral and superior temporal gyrus, as well as left caudate and anterior cingulate cortex. There were decreasing activations of bilateral visuo-cognitive, articulatory, attention, and language areas due to therapy, with stronger decreases for patients in right middle temporal gyrus/superior temporal sulcus, bilateral precuneus as well as left anterior cingulate cortex and caudate. The joint independent component analysis revealed three components indexing lesion subtypes that were associated with patient-specific recovery patterns. Activation decreases (i) of an extended frontal lesion disconnecting language pathways occurred in left inferior frontal gyrus; (ii) of a small frontal lesion were found in bilateral inferior frontal gyrus; and (iii) of a large temporo-parietal lesion occurred in bilateral inferior frontal gyrus and contralateral superior temporal gyrus. All components revealed increases in prefrontal areas. One component was negatively correlated with therapy gain. Therapy was associated exclusively with activation decreases, which could mainly be attributed to higher processing efficiency within the naming network. In our joint independent component analysis, all three lesion patterns disclosed involved deactivation of left inferior frontal gyrus. Moreover, we found evidence for increased demands on control processes. As expected, we saw partly differential reorganization profiles depending on lesion patterns. There was no compensatory deactivation for the large left inferior frontal lesion, with its less advantageous outcome probably being related to its disconnection from crucial language processing pathways.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/25928380" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a39aaa8483f120292619f32182ec8cdf" rel="nofollow" data-download="{"attachment_id":46286376,"asset_id":25928380,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46286376/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="49675445" href="https://rwth-aachen.academia.edu/KlausWillmes">Klaus Willmes</a><script data-card-contents-for-user="49675445" type="text/json">{"id":49675445,"first_name":"Klaus","last_name":"Willmes","domain_name":"rwth-aachen","page_name":"KlausWillmes","display_name":"Klaus Willmes","profile_url":"https://rwth-aachen.academia.edu/KlausWillmes?f_ri=57557","photo":"https://0.academia-photos.com/49675445/21834535/21124979/s65_klaus.willmes.jpg"}</script></span></span></li><li class="js-paper-rank-work_25928380 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="25928380"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 25928380, container: ".js-paper-rank-work_25928380", }); });</script></li><li class="js-percentile-work_25928380 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 25928380; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_25928380"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_25928380 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="25928380"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 25928380; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=25928380]").text(description); $(".js-view-count-work_25928380").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_25928380").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="25928380"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="5738" rel="nofollow" href="https://www.academia.edu/Documents/in/Aphasia">Aphasia</a>, <script data-card-contents-for-ri="5738" type="text/json">{"id":5738,"name":"Aphasia","url":"https://www.academia.edu/Documents/in/Aphasia?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="8942" rel="nofollow" href="https://www.academia.edu/Documents/in/Treatment">Treatment</a>, <script data-card-contents-for-ri="8942" type="text/json">{"id":8942,"name":"Treatment","url":"https://www.academia.edu/Documents/in/Treatment?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="57557" rel="nofollow" href="https://www.academia.edu/Documents/in/Temporal_Lobe">Temporal Lobe</a><script data-card-contents-for-ri="57557" type="text/json">{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=25928380]'), work: {"id":25928380,"title":"Therapy-induced brain reorganization patterns in aphasia","created_at":"2016-06-06T11:05:47.113-07:00","url":"https://www.academia.edu/25928380/Therapy_induced_brain_reorganization_patterns_in_aphasia?f_ri=57557","dom_id":"work_25928380","summary":"Both hemispheres are engaged in recovery from word production deficits in aphasia. Lexical therapy has been shown to induce brain reorganization even in patients with chronic aphasia. However, the interplay of factors influencing reorganization patterns still remains unresolved. We were especially interested in the relation between lesion site, therapy-induced recovery, and beneficial reorganization patterns. Thus, we applied intensive lexical therapy, which was evaluated with functional magnetic resonance imaging, to 14 chronic patients with aphasic word retrieval deficits. In a group study, we aimed to illuminate brain reorganization of the naming network in comparison with healthy controls. Moreover, we intended to analyse the data with joint independent component analysis to relate lesion sites to therapy-induced brain reorganization, and to correlate resulting components with therapy gain. As a result, we found peri-lesional and contralateral activations basically overlapping with premorbid naming networks observed in healthy subjects. Reduced activation patterns for patients compared to controls before training comprised damaged left hemisphere language areas, right precentral and superior temporal gyrus, as well as left caudate and anterior cingulate cortex. There were decreasing activations of bilateral visuo-cognitive, articulatory, attention, and language areas due to therapy, with stronger decreases for patients in right middle temporal gyrus/superior temporal sulcus, bilateral precuneus as well as left anterior cingulate cortex and caudate. The joint independent component analysis revealed three components indexing lesion subtypes that were associated with patient-specific recovery patterns. Activation decreases (i) of an extended frontal lesion disconnecting language pathways occurred in left inferior frontal gyrus; (ii) of a small frontal lesion were found in bilateral inferior frontal gyrus; and (iii) of a large temporo-parietal lesion occurred in bilateral inferior frontal gyrus and contralateral superior temporal gyrus. All components revealed increases in prefrontal areas. One component was negatively correlated with therapy gain. Therapy was associated exclusively with activation decreases, which could mainly be attributed to higher processing efficiency within the naming network. In our joint independent component analysis, all three lesion patterns disclosed involved deactivation of left inferior frontal gyrus. Moreover, we found evidence for increased demands on control processes. As expected, we saw partly differential reorganization profiles depending on lesion patterns. There was no compensatory deactivation for the large left inferior frontal lesion, with its less advantageous outcome probably being related to its disconnection from crucial language processing pathways.","downloadable_attachments":[{"id":46286376,"asset_id":25928380,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":49675445,"first_name":"Klaus","last_name":"Willmes","domain_name":"rwth-aachen","page_name":"KlausWillmes","display_name":"Klaus Willmes","profile_url":"https://rwth-aachen.academia.edu/KlausWillmes?f_ri=57557","photo":"https://0.academia-photos.com/49675445/21834535/21124979/s65_klaus.willmes.jpg"}],"research_interests":[{"id":5738,"name":"Aphasia","url":"https://www.academia.edu/Documents/in/Aphasia?f_ri=57557","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":8942,"name":"Treatment","url":"https://www.academia.edu/Documents/in/Treatment?f_ri=57557","nofollow":true},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557","nofollow":true},{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain?f_ri=57557"},{"id":119665,"name":"Reaction Time","url":"https://www.academia.edu/Documents/in/Reaction_Time?f_ri=57557"},{"id":132020,"name":"Neuronal Plasticity","url":"https://www.academia.edu/Documents/in/Neuronal_Plasticity?f_ri=57557"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=57557"},{"id":2474622,"name":"Recovery of Function","url":"https://www.academia.edu/Documents/in/Recovery_of_Function?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_13197551" data-work_id="13197551" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13197551/Thinner_cortex_in_the_frontal_lobes_in_mentally_disordered_offenders">Thinner cortex in the frontal lobes in mentally disordered offenders</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Antisocial and violent behaviour have been associated with both structural and functional brain abnormalities in the frontal and the temporal lobes. The aim of the present study was to assess cortical thickness in offenders undergoing... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_13197551" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Antisocial and violent behaviour have been associated with both structural and functional brain abnormalities in the frontal and the temporal lobes. The aim of the present study was to assess cortical thickness in offenders undergoing forensic psychiatric assessments, one group with psychopathy (PSY, n = 7) and one group with autism spectrum disorder (ASD, n = 7) compared to each other as well as to a reference group consisting of healthy non-criminal subjects (RG, n = 12). A second aim was to assess correlation between scores on a psychopathy checklist (PCL-SV) and cortical thickness. Magnetic resonance imaging (MRI) and surface-based cortical segmentation were used to calculate cortical thickness. Analyses used both regions of interest and statistical maps. When the two groups of offenders were compared, there were no differences in cortical thickness, but the PSY group had thinner cortex in the temporal lobes and in the whole right hemisphere compared to RG. There were no differences in cortical thickness between the ASD group and RG. Across subjects there was a negative correlation between PCL-SV scores and cortical thickness in the temporal lobes and the whole right hemisphere. The findings indicate that thinner cortex in the temporal lobes is present in psychopathic offenders and that these regions are important for the expression of psychopathy. However, whether thinner temporal cortex is a cause or a consequence of the antisocial behaviour is still unknown.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13197551" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="10bc5580c81ddb6c0d7db6451ec84f0f" rel="nofollow" data-download="{"attachment_id":45599448,"asset_id":13197551,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45599448/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32453617" href="https://au.academia.edu/SEskildsen">Simon Eskildsen</a><script data-card-contents-for-user="32453617" type="text/json">{"id":32453617,"first_name":"Simon","last_name":"Eskildsen","domain_name":"au","page_name":"SEskildsen","display_name":"Simon Eskildsen","profile_url":"https://au.academia.edu/SEskildsen?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_13197551 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="13197551"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 13197551, container: ".js-paper-rank-work_13197551", }); });</script></li><li class="js-percentile-work_13197551 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 13197551; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_13197551"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_13197551 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="13197551"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 13197551; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=13197551]").text(description); $(".js-view-count-work_13197551").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_13197551").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="13197551"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">18</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="237" rel="nofollow" href="https://www.academia.edu/Documents/in/Cognitive_Science">Cognitive Science</a>, <script data-card-contents-for-ri="237" type="text/json">{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="635" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychiatry">Psychiatry</a>, <script data-card-contents-for-ri="635" type="text/json">{"id":635,"name":"Psychiatry","url":"https://www.academia.edu/Documents/in/Psychiatry?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="1697" rel="nofollow" href="https://www.academia.edu/Documents/in/Violence">Violence</a>, <script data-card-contents-for-ri="1697" type="text/json">{"id":1697,"name":"Violence","url":"https://www.academia.edu/Documents/in/Violence?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a><script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=13197551]'), work: {"id":13197551,"title":"Thinner cortex in the frontal lobes in mentally disordered offenders","created_at":"2015-06-23T00:37:45.571-07:00","url":"https://www.academia.edu/13197551/Thinner_cortex_in_the_frontal_lobes_in_mentally_disordered_offenders?f_ri=57557","dom_id":"work_13197551","summary":"Antisocial and violent behaviour have been associated with both structural and functional brain abnormalities in the frontal and the temporal lobes. The aim of the present study was to assess cortical thickness in offenders undergoing forensic psychiatric assessments, one group with psychopathy (PSY, n = 7) and one group with autism spectrum disorder (ASD, n = 7) compared to each other as well as to a reference group consisting of healthy non-criminal subjects (RG, n = 12). A second aim was to assess correlation between scores on a psychopathy checklist (PCL-SV) and cortical thickness. Magnetic resonance imaging (MRI) and surface-based cortical segmentation were used to calculate cortical thickness. Analyses used both regions of interest and statistical maps. When the two groups of offenders were compared, there were no differences in cortical thickness, but the PSY group had thinner cortex in the temporal lobes and in the whole right hemisphere compared to RG. There were no differences in cortical thickness between the ASD group and RG. Across subjects there was a negative correlation between PCL-SV scores and cortical thickness in the temporal lobes and the whole right hemisphere. The findings indicate that thinner cortex in the temporal lobes is present in psychopathic offenders and that these regions are important for the expression of psychopathy. However, whether thinner temporal cortex is a cause or a consequence of the antisocial behaviour is still unknown.","downloadable_attachments":[{"id":45599448,"asset_id":13197551,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32453617,"first_name":"Simon","last_name":"Eskildsen","domain_name":"au","page_name":"SEskildsen","display_name":"Simon Eskildsen","profile_url":"https://au.academia.edu/SEskildsen?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true},{"id":635,"name":"Psychiatry","url":"https://www.academia.edu/Documents/in/Psychiatry?f_ri=57557","nofollow":true},{"id":1697,"name":"Violence","url":"https://www.academia.edu/Documents/in/Violence?f_ri=57557","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":44273,"name":"Antisocial Personality Disorder","url":"https://www.academia.edu/Documents/in/Antisocial_Personality_Disorder?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=57557"},{"id":118523,"name":"Checklist","url":"https://www.academia.edu/Documents/in/Checklist?f_ri=57557"},{"id":123287,"name":"Three Dimensional Imaging","url":"https://www.academia.edu/Documents/in/Three_Dimensional_Imaging?f_ri=57557"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=57557"},{"id":171144,"name":"Mental Disorders","url":"https://www.academia.edu/Documents/in/Mental_Disorders?f_ri=57557"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=57557"},{"id":301567,"name":"Prisoners","url":"https://www.academia.edu/Documents/in/Prisoners?f_ri=57557"},{"id":406036,"name":"Parietal Lobe","url":"https://www.academia.edu/Documents/in/Parietal_Lobe?f_ri=57557"},{"id":1000427,"name":"Reference Values","url":"https://www.academia.edu/Documents/in/Reference_Values?f_ri=57557"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=57557"},{"id":1257483,"name":"Frontal Lobe","url":"https://www.academia.edu/Documents/in/Frontal_Lobe?f_ri=57557"},{"id":1766624,"name":"Occipital Lobe","url":"https://www.academia.edu/Documents/in/Occipital_Lobe?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_13737510 coauthored" data-work_id="13737510" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13737510/Comparison_of_spherical_and_realistically_shaped_boundary_element_head_models_for_transcranial_magnetic_stimulation_navigation">Comparison of spherical and realistically shaped boundary element head models for transcranial magnetic stimulation navigation</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Volume conductor models influence TMS electric field estimates. Present TMS navigation systems use computationally simple spherical conductor models. Anatomically realistic boundary-element models can improve TMS targeting especially at... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_13737510" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Volume conductor models influence TMS electric field estimates. Present TMS navigation systems use computationally simple spherical conductor models. Anatomically realistic boundary-element models can improve TMS targeting especially at prefrontal and temporal regions.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13737510" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="83b8bd0aeb44ac96390e9c4a35a9e977" rel="nofollow" data-download="{"attachment_id":45005633,"asset_id":13737510,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45005633/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32859380" href="https://independent.academia.edu/AapoNummenmaa">Aapo Nummenmaa</a><script data-card-contents-for-user="32859380" type="text/json">{"id":32859380,"first_name":"Aapo","last_name":"Nummenmaa","domain_name":"independent","page_name":"AapoNummenmaa","display_name":"Aapo Nummenmaa","profile_url":"https://independent.academia.edu/AapoNummenmaa?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-13737510">+1</span><div class="hidden js-additional-users-13737510"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://aalto-fi.academia.edu/RistoIlmoniemi">Risto Ilmoniemi</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-13737510'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-13737510').html(); 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Present TMS navigation systems use computationally simple spherical conductor models. Anatomically realistic boundary-element models can improve TMS targeting especially at prefrontal and temporal regions.","downloadable_attachments":[{"id":45005633,"asset_id":13737510,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32859380,"first_name":"Aapo","last_name":"Nummenmaa","domain_name":"independent","page_name":"AapoNummenmaa","display_name":"Aapo Nummenmaa","profile_url":"https://independent.academia.edu/AapoNummenmaa?f_ri=57557","photo":"/images/s65_no_pic.png"},{"id":8951497,"first_name":"Risto","last_name":"Ilmoniemi","domain_name":"aalto-fi","page_name":"RistoIlmoniemi","display_name":"Risto Ilmoniemi","profile_url":"https://aalto-fi.academia.edu/RistoIlmoniemi?f_ri=57557","photo":"https://0.academia-photos.com/8951497/2927155/3424780/s65_risto.ilmoniemi.png"}],"research_interests":[{"id":48,"name":"Engineering","url":"https://www.academia.edu/Documents/in/Engineering?f_ri=57557","nofollow":true},{"id":1026,"name":"Psychophysiology","url":"https://www.academia.edu/Documents/in/Psychophysiology?f_ri=57557","nofollow":true},{"id":5356,"name":"Magnetoencephalography","url":"https://www.academia.edu/Documents/in/Magnetoencephalography?f_ri=57557","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":6565,"name":"Transcranial Magnetic Stimulation","url":"https://www.academia.edu/Documents/in/Transcranial_Magnetic_Stimulation?f_ri=57557"},{"id":10904,"name":"Electroencephalography","url":"https://www.academia.edu/Documents/in/Electroencephalography?f_ri=57557"},{"id":28576,"name":"Prefrontal Cortex","url":"https://www.academia.edu/Documents/in/Prefrontal_Cortex?f_ri=57557"},{"id":52176,"name":"Brain Mapping","url":"https://www.academia.edu/Documents/in/Brain_Mapping?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain?f_ri=57557"},{"id":98495,"name":"Electromagnetic modeling","url":"https://www.academia.edu/Documents/in/Electromagnetic_modeling?f_ri=57557"},{"id":127595,"name":"Boundary Element Method","url":"https://www.academia.edu/Documents/in/Boundary_Element_Method?f_ri=57557"},{"id":131236,"name":"Electromagnetic Fields","url":"https://www.academia.edu/Documents/in/Electromagnetic_Fields?f_ri=57557"},{"id":263020,"name":"Clinical Neurophysiology","url":"https://www.academia.edu/Documents/in/Clinical_Neurophysiology?f_ri=57557"},{"id":277066,"name":"Head","url":"https://www.academia.edu/Documents/in/Head?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_13879623" data-work_id="13879623" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13879623/Brain_morphology_in_normal_and_dyslexic_children_The_influence_of_sex_and_age">Brain morphology in normal and dyslexic children: The influence of sex and age</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Morphometric magnetic resonance imaging techniques were used to compare the convolutional surface area of the planum temporale, temporal lobe volume and superior surface area, and an estimate of overall brain volume in a homogeneous... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_13879623" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Morphometric magnetic resonance imaging techniques were used to compare the convolutional surface area of the planum temporale, temporal lobe volume and superior surface area, and an estimate of overall brain volume in a homogeneous sample of 17 dyslexic children (7 girls) and 14 nonimpaired children (7 girls). Substantial sex differences were apparent for all measured regions, with all the measurements in boys being significantly larger. Age, even within the narrow range employed here (7.5-9.7 years), was positively correlated with the size of each brain region. While From the *Child Study Center and the Departments of ?Diagnostic</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13879623" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="982bda51192e22c97c5990e5ffe9e689" rel="nofollow" data-download="{"attachment_id":44844879,"asset_id":13879623,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44844879/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32958587" href="https://upenn.academia.edu/RobertSchultz">Robert Schultz</a><script data-card-contents-for-user="32958587" type="text/json">{"id":32958587,"first_name":"Robert","last_name":"Schultz","domain_name":"upenn","page_name":"RobertSchultz","display_name":"Robert Schultz","profile_url":"https://upenn.academia.edu/RobertSchultz?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_13879623 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="13879623"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 13879623, container: ".js-paper-rank-work_13879623", }); 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$(".js-view-count[data-work-id=13879623]").text(description); $(".js-view-count-work_13879623").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_13879623").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="13879623"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">15</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="25052" rel="nofollow" href="https://www.academia.edu/Documents/in/Dyslexia">Dyslexia</a>, <script data-card-contents-for-ri="25052" type="text/json">{"id":25052,"name":"Dyslexia","url":"https://www.academia.edu/Documents/in/Dyslexia?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="57557" rel="nofollow" href="https://www.academia.edu/Documents/in/Temporal_Lobe">Temporal Lobe</a>, <script data-card-contents-for-ri="57557" type="text/json">{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="61474" rel="nofollow" href="https://www.academia.edu/Documents/in/Brain">Brain</a><script data-card-contents-for-ri="61474" type="text/json">{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=13879623]'), work: {"id":13879623,"title":"Brain morphology in normal and dyslexic children: The influence of sex and age","created_at":"2015-07-10T05:12:26.568-07:00","url":"https://www.academia.edu/13879623/Brain_morphology_in_normal_and_dyslexic_children_The_influence_of_sex_and_age?f_ri=57557","dom_id":"work_13879623","summary":"Morphometric magnetic resonance imaging techniques were used to compare the convolutional surface area of the planum temporale, temporal lobe volume and superior surface area, and an estimate of overall brain volume in a homogeneous sample of 17 dyslexic children (7 girls) and 14 nonimpaired children (7 girls). Substantial sex differences were apparent for all measured regions, with all the measurements in boys being significantly larger. Age, even within the narrow range employed here (7.5-9.7 years), was positively correlated with the size of each brain region. While From the *Child Study Center and the Departments of ?Diagnostic","downloadable_attachments":[{"id":44844879,"asset_id":13879623,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32958587,"first_name":"Robert","last_name":"Schultz","domain_name":"upenn","page_name":"RobertSchultz","display_name":"Robert Schultz","profile_url":"https://upenn.academia.edu/RobertSchultz?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":25052,"name":"Dyslexia","url":"https://www.academia.edu/Documents/in/Dyslexia?f_ri=57557","nofollow":true},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557","nofollow":true},{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain?f_ri=57557","nofollow":true},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=57557"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=57557"},{"id":359001,"name":"Optometry and Ophthalmology","url":"https://www.academia.edu/Documents/in/Optometry_and_Ophthalmology?f_ri=57557"},{"id":413192,"name":"Sex Factors","url":"https://www.academia.edu/Documents/in/Sex_Factors?f_ri=57557"},{"id":413194,"name":"Analysis of Variance","url":"https://www.academia.edu/Documents/in/Analysis_of_Variance?f_ri=57557"},{"id":546419,"name":"Age Factors","url":"https://www.academia.edu/Documents/in/Age_Factors?f_ri=57557"},{"id":644084,"name":"Intelligence tests","url":"https://www.academia.edu/Documents/in/Intelligence_tests?f_ri=57557"},{"id":710565,"name":"Annals","url":"https://www.academia.edu/Documents/in/Annals?f_ri=57557"},{"id":1000427,"name":"Reference Values","url":"https://www.academia.edu/Documents/in/Reference_Values?f_ri=57557"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=57557"},{"id":2234200,"name":"Functional Laterality","url":"https://www.academia.edu/Documents/in/Functional_Laterality?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_14047565" data-work_id="14047565" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/14047565/Whole_brain_voxel_based_statistical_analysis_of_gray_matter_and_white_matter_in_temporal_lobe_epilepsy">Whole-brain voxel-based statistical analysis of gray matter and white matter in temporal lobe epilepsy</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Volumetric MRI studies based on manual labeling of selected anatomical structures have provided in vivo evidence that brain abnormalities associated with temporal lobe epilepsy (TLE) extend beyond the hippocampus. Voxel-based morphometry... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_14047565" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Volumetric MRI studies based on manual labeling of selected anatomical structures have provided in vivo evidence that brain abnormalities associated with temporal lobe epilepsy (TLE) extend beyond the hippocampus. Voxel-based morphometry (VBM) is a fully automated image analysis technique allowing identification of regional differences in gray matter (GM) and white matter (WM) between groups of subjects without a prior region of interest. The purpose of this study was to determine whole-brain GM and WM changes in TLE and to investigate the relationship between these abnormalities and clinical parameters. We studied 85 patients with pharmacologically intractable TLE and unilateral hippocampal atrophy and 47 age-and sex-matched healthy control subjects. The seizure focus was right sided in 40 patients and left sided in 45. Student's t test statistical maps of differences between patients' and controls' GM and WM concentrations were obtained using a general linear model. A further regression against duration of epilepsy, age of onset, presence of febrile convulsions, and secondary generalized seizures was performed with the TLE population. Voxel-based morphometry revealed that GM pathology in TLE extends beyond the hippocampus involving other limbic areas such as the cingulum and the thalamus, as well as extralimbic areas, particularly the frontal lobe. White matter reduction was found only ipsilateral to the seizure focus, including the temporopolar, entorhinal, and perirhinal areas. This pattern of structural changes is suggestive of disconnection involving preferentially frontolimbic pathways in patients with pharmacologically intractable TLE. D 2004 Elsevier Inc. All rights reserved.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/14047565" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="6848cdee97427bd97f8b4e3e6cbf6283" rel="nofollow" data-download="{"attachment_id":44665160,"asset_id":14047565,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44665160/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33068513" href="https://uq.academia.edu/AndrewJanke">Andrew Janke</a><script data-card-contents-for-user="33068513" type="text/json">{"id":33068513,"first_name":"Andrew","last_name":"Janke","domain_name":"uq","page_name":"AndrewJanke","display_name":"Andrew Janke","profile_url":"https://uq.academia.edu/AndrewJanke?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_14047565 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="14047565"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 14047565, container: ".js-paper-rank-work_14047565", }); 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$(".js-view-count[data-work-id=14047565]").text(description); $(".js-view-count-work_14047565").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_14047565").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="14047565"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">18</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="5187" rel="nofollow" href="https://www.academia.edu/Documents/in/Statistical_Analysis">Statistical Analysis</a>, <script data-card-contents-for-ri="5187" type="text/json">{"id":5187,"name":"Statistical Analysis","url":"https://www.academia.edu/Documents/in/Statistical_Analysis?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="9351" rel="nofollow" href="https://www.academia.edu/Documents/in/Image_Analysis">Image Analysis</a>, <script data-card-contents-for-ri="9351" type="text/json">{"id":9351,"name":"Image Analysis","url":"https://www.academia.edu/Documents/in/Image_Analysis?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a><script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=14047565]'), work: {"id":14047565,"title":"Whole-brain voxel-based statistical analysis of gray matter and white matter in temporal lobe epilepsy","created_at":"2015-07-14T12:42:20.313-07:00","url":"https://www.academia.edu/14047565/Whole_brain_voxel_based_statistical_analysis_of_gray_matter_and_white_matter_in_temporal_lobe_epilepsy?f_ri=57557","dom_id":"work_14047565","summary":"Volumetric MRI studies based on manual labeling of selected anatomical structures have provided in vivo evidence that brain abnormalities associated with temporal lobe epilepsy (TLE) extend beyond the hippocampus. Voxel-based morphometry (VBM) is a fully automated image analysis technique allowing identification of regional differences in gray matter (GM) and white matter (WM) between groups of subjects without a prior region of interest. The purpose of this study was to determine whole-brain GM and WM changes in TLE and to investigate the relationship between these abnormalities and clinical parameters. We studied 85 patients with pharmacologically intractable TLE and unilateral hippocampal atrophy and 47 age-and sex-matched healthy control subjects. The seizure focus was right sided in 40 patients and left sided in 45. Student's t test statistical maps of differences between patients' and controls' GM and WM concentrations were obtained using a general linear model. A further regression against duration of epilepsy, age of onset, presence of febrile convulsions, and secondary generalized seizures was performed with the TLE population. Voxel-based morphometry revealed that GM pathology in TLE extends beyond the hippocampus involving other limbic areas such as the cingulum and the thalamus, as well as extralimbic areas, particularly the frontal lobe. White matter reduction was found only ipsilateral to the seizure focus, including the temporopolar, entorhinal, and perirhinal areas. This pattern of structural changes is suggestive of disconnection involving preferentially frontolimbic pathways in patients with pharmacologically intractable TLE. D 2004 Elsevier Inc. All rights reserved.","downloadable_attachments":[{"id":44665160,"asset_id":14047565,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33068513,"first_name":"Andrew","last_name":"Janke","domain_name":"uq","page_name":"AndrewJanke","display_name":"Andrew Janke","profile_url":"https://uq.academia.edu/AndrewJanke?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":5187,"name":"Statistical Analysis","url":"https://www.academia.edu/Documents/in/Statistical_Analysis?f_ri=57557","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":9351,"name":"Image Analysis","url":"https://www.academia.edu/Documents/in/Image_Analysis?f_ri=57557","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=57557","nofollow":true},{"id":32913,"name":"Neuroimmunology","url":"https://www.academia.edu/Documents/in/Neuroimmunology?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain?f_ri=57557"},{"id":103260,"name":"Neuroimage","url":"https://www.academia.edu/Documents/in/Neuroimage?f_ri=57557"},{"id":103265,"name":"Voxel Based Morphometry","url":"https://www.academia.edu/Documents/in/Voxel_Based_Morphometry?f_ri=57557"},{"id":128608,"name":"Temporal Lobe Epilepsy","url":"https://www.academia.edu/Documents/in/Temporal_Lobe_Epilepsy?f_ri=57557"},{"id":213801,"name":"Structural Change","url":"https://www.academia.edu/Documents/in/Structural_Change?f_ri=57557"},{"id":362036,"name":"White matter","url":"https://www.academia.edu/Documents/in/White_matter?f_ri=57557"},{"id":490996,"name":"General Linear Model","url":"https://www.academia.edu/Documents/in/General_Linear_Model?f_ri=57557"},{"id":494840,"name":"Limbic System","url":"https://www.academia.edu/Documents/in/Limbic_System?f_ri=57557"},{"id":1250577,"name":"Gray Matter","url":"https://www.academia.edu/Documents/in/Gray_Matter?f_ri=57557"},{"id":1257483,"name":"Frontal Lobe","url":"https://www.academia.edu/Documents/in/Frontal_Lobe?f_ri=57557"},{"id":1372278,"name":"Region of Interest","url":"https://www.academia.edu/Documents/in/Region_of_Interest?f_ri=57557"},{"id":1489115,"name":"Age of Onset","url":"https://www.academia.edu/Documents/in/Age_of_Onset?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_22615868" data-work_id="22615868" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/22615868/Attention_to_3_D_Shape_3_D_Motion_and_Texture_in_3_D_Structure_from_Motion_Displays">Attention to 3-D Shape, 3-D Motion, and Texture in 3-D Structure from Motion Displays</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">& We used fMRI to directly compare the neural substrates of three-dimensional (3-D) shape and motion processing for realistic textured objects rotating in depth. Subjects made judgments about several different attributes of these objects,... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_22615868" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">& We used fMRI to directly compare the neural substrates of three-dimensional (3-D) shape and motion processing for realistic textured objects rotating in depth. Subjects made judgments about several different attributes of these objects, including 3-D shape, the 3-D motion, and the scale of surface texture. For all of these tasks, we equated visual input, motor output, and task difficulty, and we controlled for differ-ences in spatial attention. Judgments about 3-D shape from motion involve both parietal and occipito-temporal regions. The processing of 3-D shape is associated with the analysis of 3-D motion in parietal regions and the analysis of surface texture in occipito-temporal regions, which is consistent with the different behavioral roles that are typically attributed to the dorsal and ventral processing streams. &</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/22615868" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="9a31db6a2580ad941bee2a8acc05cf00" rel="nofollow" data-download="{"attachment_id":43214522,"asset_id":22615868,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/43214522/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="27681192" href="https://kuleuven.academia.edu/HendrikPeuskens">Hendrik Peuskens</a><script data-card-contents-for-user="27681192" type="text/json">{"id":27681192,"first_name":"Hendrik","last_name":"Peuskens","domain_name":"kuleuven","page_name":"HendrikPeuskens","display_name":"Hendrik Peuskens","profile_url":"https://kuleuven.academia.edu/HendrikPeuskens?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_22615868 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="22615868"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 22615868, container: ".js-paper-rank-work_22615868", }); 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$(".js-view-count[data-work-id=22615868]").text(description); $(".js-view-count-work_22615868").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_22615868").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="22615868"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">19</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="237" rel="nofollow" href="https://www.academia.edu/Documents/in/Cognitive_Science">Cognitive Science</a>, <script data-card-contents-for-ri="237" type="text/json">{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="7736" rel="nofollow" href="https://www.academia.edu/Documents/in/Attention">Attention</a><script data-card-contents-for-ri="7736" type="text/json">{"id":7736,"name":"Attention","url":"https://www.academia.edu/Documents/in/Attention?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=22615868]'), work: {"id":22615868,"title":"Attention to 3-D Shape, 3-D Motion, and Texture in 3-D Structure from Motion Displays","created_at":"2016-02-29T14:02:07.093-08:00","url":"https://www.academia.edu/22615868/Attention_to_3_D_Shape_3_D_Motion_and_Texture_in_3_D_Structure_from_Motion_Displays?f_ri=57557","dom_id":"work_22615868","summary":"\u0026 We used fMRI to directly compare the neural substrates of three-dimensional (3-D) shape and motion processing for realistic textured objects rotating in depth. Subjects made judgments about several different attributes of these objects, including 3-D shape, the 3-D motion, and the scale of surface texture. For all of these tasks, we equated visual input, motor output, and task difficulty, and we controlled for differ-ences in spatial attention. Judgments about 3-D shape from motion involve both parietal and occipito-temporal regions. The processing of 3-D shape is associated with the analysis of 3-D motion in parietal regions and the analysis of surface texture in occipito-temporal regions, which is consistent with the different behavioral roles that are typically attributed to the dorsal and ventral processing streams. \u0026","downloadable_attachments":[{"id":43214522,"asset_id":22615868,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":27681192,"first_name":"Hendrik","last_name":"Peuskens","domain_name":"kuleuven","page_name":"HendrikPeuskens","display_name":"Hendrik Peuskens","profile_url":"https://kuleuven.academia.edu/HendrikPeuskens?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true},{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":7736,"name":"Attention","url":"https://www.academia.edu/Documents/in/Attention?f_ri=57557","nofollow":true},{"id":13493,"name":"Motion perception","url":"https://www.academia.edu/Documents/in/Motion_perception?f_ri=57557"},{"id":21548,"name":"Cognitive Neuroscience","url":"https://www.academia.edu/Documents/in/Cognitive_Neuroscience?f_ri=57557"},{"id":35888,"name":"Cognitive","url":"https://www.academia.edu/Documents/in/Cognitive?f_ri=57557"},{"id":41031,"name":"Structure from Motion","url":"https://www.academia.edu/Documents/in/Structure_from_Motion?f_ri=57557"},{"id":56633,"name":"Spatial Attention","url":"https://www.academia.edu/Documents/in/Spatial_Attention?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":82283,"name":"Form perception","url":"https://www.academia.edu/Documents/in/Form_perception?f_ri=57557"},{"id":124863,"name":"Motion processing","url":"https://www.academia.edu/Documents/in/Motion_processing?f_ri=57557"},{"id":207295,"name":"Task Difficulty","url":"https://www.academia.edu/Documents/in/Task_Difficulty?f_ri=57557"},{"id":406036,"name":"Parietal Lobe","url":"https://www.academia.edu/Documents/in/Parietal_Lobe?f_ri=57557"},{"id":504035,"name":"Three Dimensional","url":"https://www.academia.edu/Documents/in/Three_Dimensional?f_ri=57557"},{"id":818658,"name":"Rotation","url":"https://www.academia.edu/Documents/in/Rotation?f_ri=57557"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=57557"},{"id":1749681,"name":"Surface Texture","url":"https://www.academia.edu/Documents/in/Surface_Texture?f_ri=57557"},{"id":1766624,"name":"Occipital Lobe","url":"https://www.academia.edu/Documents/in/Occipital_Lobe?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_20167127" data-work_id="20167127" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/20167127/Clinical_outcomes_and_late_endocrine_neurocognitive_and_visual_profiles_of_proton_radiation_for_pediatric_low_grade_gliomas">Clinical outcomes and late endocrine, neurocognitive, and visual profiles of proton radiation for pediatric low-grade gliomas</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Primary low-grade gliomas are common brain tumors of childhood, many of which require radiation therapy (RT) as definitive treatment. Increased conformality of RT could decrease the incidence and severity of late effects. We report our... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_20167127" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Primary low-grade gliomas are common brain tumors of childhood, many of which require radiation therapy (RT) as definitive treatment. Increased conformality of RT could decrease the incidence and severity of late effects. We report our experience with 32 pediatric patients treated with proton RT. Thirty-two pediatric patients with low-grade gliomas of the brain or spinal cord were treated with proton RT from 1995 to 2007. Sixteen patients received at least 1 regimen of chemotherapy before definitive RT. The median radiation dose was 52.2 GyRBE (48.6-54 GyRBE). The median age at treatment was 11.0 years (range, 2.7-21.5 years), with a median follow-up time of 7.6 years (range, 3.2-18.2 years). The 6-year and 8-year rates of progression-free survival were 89.7% and 82.8%, respectively, with an 8-year overall survival of 100%. For the subset of patients who received serial neurocognitive testing, there were no significant declines in Full-Scale Intelligence Quotient (P=.80), with a med...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/20167127" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="d8663145a48242201c980648f3c5edc1" rel="nofollow" data-download="{"attachment_id":41245570,"asset_id":20167127,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/41245570/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="41285885" href="https://hms-harvard.academia.edu/NancyTarbell">Nancy Tarbell</a><script data-card-contents-for-user="41285885" type="text/json">{"id":41285885,"first_name":"Nancy","last_name":"Tarbell","domain_name":"hms-harvard","page_name":"NancyTarbell","display_name":"Nancy Tarbell","profile_url":"https://hms-harvard.academia.edu/NancyTarbell?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_20167127 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="20167127"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 20167127, container: ".js-paper-rank-work_20167127", }); });</script></li><li class="js-percentile-work_20167127 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 20167127; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_20167127"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_20167127 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="20167127"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 20167127; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=20167127]").text(description); $(".js-view-count-work_20167127").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_20167127").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="20167127"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">15</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="2674" rel="nofollow" href="https://www.academia.edu/Documents/in/Intelligence">Intelligence</a>, <script data-card-contents-for-ri="2674" type="text/json">{"id":2674,"name":"Intelligence","url":"https://www.academia.edu/Documents/in/Intelligence?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4212" rel="nofollow" href="https://www.academia.edu/Documents/in/Cognition">Cognition</a>, <script data-card-contents-for-ri="4212" type="text/json">{"id":4212,"name":"Cognition","url":"https://www.academia.edu/Documents/in/Cognition?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="12426" rel="nofollow" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a>, <script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a><script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=20167127]'), work: {"id":20167127,"title":"Clinical outcomes and late endocrine, neurocognitive, and visual profiles of proton radiation for pediatric low-grade gliomas","created_at":"2016-01-11T08:12:36.885-08:00","url":"https://www.academia.edu/20167127/Clinical_outcomes_and_late_endocrine_neurocognitive_and_visual_profiles_of_proton_radiation_for_pediatric_low_grade_gliomas?f_ri=57557","dom_id":"work_20167127","summary":"Primary low-grade gliomas are common brain tumors of childhood, many of which require radiation therapy (RT) as definitive treatment. Increased conformality of RT could decrease the incidence and severity of late effects. We report our experience with 32 pediatric patients treated with proton RT. Thirty-two pediatric patients with low-grade gliomas of the brain or spinal cord were treated with proton RT from 1995 to 2007. Sixteen patients received at least 1 regimen of chemotherapy before definitive RT. The median radiation dose was 52.2 GyRBE (48.6-54 GyRBE). The median age at treatment was 11.0 years (range, 2.7-21.5 years), with a median follow-up time of 7.6 years (range, 3.2-18.2 years). The 6-year and 8-year rates of progression-free survival were 89.7% and 82.8%, respectively, with an 8-year overall survival of 100%. For the subset of patients who received serial neurocognitive testing, there were no significant declines in Full-Scale Intelligence Quotient (P=.80), with a med...","downloadable_attachments":[{"id":41245570,"asset_id":20167127,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":41285885,"first_name":"Nancy","last_name":"Tarbell","domain_name":"hms-harvard","page_name":"NancyTarbell","display_name":"Nancy Tarbell","profile_url":"https://hms-harvard.academia.edu/NancyTarbell?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":2674,"name":"Intelligence","url":"https://www.academia.edu/Documents/in/Intelligence?f_ri=57557","nofollow":true},{"id":4212,"name":"Cognition","url":"https://www.academia.edu/Documents/in/Cognition?f_ri=57557","nofollow":true},{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=57557","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=57557","nofollow":true},{"id":57556,"name":"Hippocampus","url":"https://www.academia.edu/Documents/in/Hippocampus?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=57557"},{"id":76383,"name":"Glioma","url":"https://www.academia.edu/Documents/in/Glioma?f_ri=57557"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=57557"},{"id":238190,"name":"Proton Therapy","url":"https://www.academia.edu/Documents/in/Proton_Therapy?f_ri=57557"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=57557"},{"id":293670,"name":"Pituitary Gland","url":"https://www.academia.edu/Documents/in/Pituitary_Gland?f_ri=57557"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=57557"},{"id":546419,"name":"Age Factors","url":"https://www.academia.edu/Documents/in/Age_Factors?f_ri=57557"},{"id":1425045,"name":"Brain Neoplasms","url":"https://www.academia.edu/Documents/in/Brain_Neoplasms?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_8591532" data-work_id="8591532" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/8591532/The_role_of_the_posterior_superior_temporal_sulcus_in_the_processing_of_unmarked_transitivity">The role of the posterior superior temporal sulcus in the processing of unmarked transitivity</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Is it living or not? The ability to differentiate between animate and inanimate entities is of considerable value in everyday life, since it allows for the dissociation of individuals that may willfully cause an action from objects that... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_8591532" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Is it living or not? The ability to differentiate between animate and inanimate entities is of considerable value in everyday life, since it allows for the dissociation of individuals that may willfully cause an action from objects that cannot. The present fMRI study aimed to shed light on the neural correlates of animacy at a relational-interpretive level, i.e. on the role of animacy in the establishment of relations between entities that are more or less likely to cause an event and differ in their potential to act volitionally. To this end, we investigated the processing of visually presented transitive German sentences (nominative-accusative structures) in which the factors animacy and argument order were manipulated. The relations between the arguments differed in that the animate subject either acted on an inanimate object (a very natural construction in terms of transitivity) or on an animate object (resulting in a sentence deviating from an unmarked transitive structure). Participants performed an acceptability judgment task. Violations of unmarked transitivity yielded a significant activation increase within the posterior left superior temporal sulcus (pSTS), thus suggesting a specific role of this cortical region in the relational use of animacy information. This result indicates that the influence of animacy as a relational feature differs from the impact of this parameter on the word level and is in line with other neuroimaging studies showing an engagement of the pSTS when a matching between syntax and semantics is required. A comparison between object-and subject-initial conditions further revealed a robust effect of argument order in the pars opercularis of the left inferior frontal gyrus (a subregion of Broca's area), thereby replicating previous findings demonstrating a sensitivity of this region to finegrained language-specific linearization rules.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/8591532" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="5103ef4d8d4673099741ae4fc1137847" rel="nofollow" data-download="{"attachment_id":48047550,"asset_id":8591532,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48047550/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="17767812" href="https://unisa-au.academia.edu/InaBornkesselSchlesewsky">Ina Bornkessel-Schlesewsky</a><script data-card-contents-for-user="17767812" type="text/json">{"id":17767812,"first_name":"Ina","last_name":"Bornkessel-Schlesewsky","domain_name":"unisa-au","page_name":"InaBornkesselSchlesewsky","display_name":"Ina Bornkessel-Schlesewsky","profile_url":"https://unisa-au.academia.edu/InaBornkesselSchlesewsky?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_8591532 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="8591532"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 8591532, container: ".js-paper-rank-work_8591532", }); });</script></li><li class="js-percentile-work_8591532 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 8591532; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_8591532"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_8591532 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="8591532"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 8591532; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=8591532]").text(description); $(".js-view-count-work_8591532").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_8591532").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="8591532"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">12</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="1681" rel="nofollow" href="https://www.academia.edu/Documents/in/Decision_Making">Decision Making</a>, <script data-card-contents-for-ri="1681" type="text/json">{"id":1681,"name":"Decision Making","url":"https://www.academia.edu/Documents/in/Decision_Making?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4972" rel="nofollow" href="https://www.academia.edu/Documents/in/Psycholinguistics">Psycholinguistics</a>, <script data-card-contents-for-ri="4972" type="text/json">{"id":4972,"name":"Psycholinguistics","url":"https://www.academia.edu/Documents/in/Psycholinguistics?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="9471" rel="nofollow" href="https://www.academia.edu/Documents/in/Reading">Reading</a><script data-card-contents-for-ri="9471" type="text/json">{"id":9471,"name":"Reading","url":"https://www.academia.edu/Documents/in/Reading?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=8591532]'), work: {"id":8591532,"title":"The role of the posterior superior temporal sulcus in the processing of unmarked transitivity","created_at":"2014-10-01T14:16:46.864-07:00","url":"https://www.academia.edu/8591532/The_role_of_the_posterior_superior_temporal_sulcus_in_the_processing_of_unmarked_transitivity?f_ri=57557","dom_id":"work_8591532","summary":"Is it living or not? The ability to differentiate between animate and inanimate entities is of considerable value in everyday life, since it allows for the dissociation of individuals that may willfully cause an action from objects that cannot. The present fMRI study aimed to shed light on the neural correlates of animacy at a relational-interpretive level, i.e. on the role of animacy in the establishment of relations between entities that are more or less likely to cause an event and differ in their potential to act volitionally. To this end, we investigated the processing of visually presented transitive German sentences (nominative-accusative structures) in which the factors animacy and argument order were manipulated. The relations between the arguments differed in that the animate subject either acted on an inanimate object (a very natural construction in terms of transitivity) or on an animate object (resulting in a sentence deviating from an unmarked transitive structure). Participants performed an acceptability judgment task. Violations of unmarked transitivity yielded a significant activation increase within the posterior left superior temporal sulcus (pSTS), thus suggesting a specific role of this cortical region in the relational use of animacy information. This result indicates that the influence of animacy as a relational feature differs from the impact of this parameter on the word level and is in line with other neuroimaging studies showing an engagement of the pSTS when a matching between syntax and semantics is required. A comparison between object-and subject-initial conditions further revealed a robust effect of argument order in the pars opercularis of the left inferior frontal gyrus (a subregion of Broca's area), thereby replicating previous findings demonstrating a sensitivity of this region to finegrained language-specific linearization rules.","downloadable_attachments":[{"id":48047550,"asset_id":8591532,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":17767812,"first_name":"Ina","last_name":"Bornkessel-Schlesewsky","domain_name":"unisa-au","page_name":"InaBornkesselSchlesewsky","display_name":"Ina Bornkessel-Schlesewsky","profile_url":"https://unisa-au.academia.edu/InaBornkesselSchlesewsky?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":1681,"name":"Decision Making","url":"https://www.academia.edu/Documents/in/Decision_Making?f_ri=57557","nofollow":true},{"id":4972,"name":"Psycholinguistics","url":"https://www.academia.edu/Documents/in/Psycholinguistics?f_ri=57557","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":9471,"name":"Reading","url":"https://www.academia.edu/Documents/in/Reading?f_ri=57557","nofollow":true},{"id":18174,"name":"Language","url":"https://www.academia.edu/Documents/in/Language?f_ri=57557"},{"id":33887,"name":"Language Comprehension","url":"https://www.academia.edu/Documents/in/Language_Comprehension?f_ri=57557"},{"id":41286,"name":"Everyday Life","url":"https://www.academia.edu/Documents/in/Everyday_Life?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":91668,"name":"Transitivity","url":"https://www.academia.edu/Documents/in/Transitivity?f_ri=57557"},{"id":103260,"name":"Neuroimage","url":"https://www.academia.edu/Documents/in/Neuroimage?f_ri=57557"},{"id":1119718,"name":"Initial Condition","url":"https://www.academia.edu/Documents/in/Initial_Condition?f_ri=57557"},{"id":1257483,"name":"Frontal Lobe","url":"https://www.academia.edu/Documents/in/Frontal_Lobe?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_80025266" data-work_id="80025266" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/80025266/Visual_Field_Defects_in_Selective_Amygdalohippocampectomy_for_Hippocampal_Sclerosis">Visual Field Defects in Selective Amygdalohippocampectomy for Hippocampal Sclerosis</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">OBJECTIVE Meyer&#39;s loop, the most vulnerable part of the optic radiations during approaches to the temporomedial region, extends to the tip of the temporal horn and is often encountered in epilepsy surgery. The risk of damaging... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_80025266" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">OBJECTIVE Meyer&#39;s loop, the most vulnerable part of the optic radiations during approaches to the temporomedial region, extends to the tip of the temporal horn and is often encountered in epilepsy surgery. The risk of damaging Meyer&#39;s loop during transsylvian selective amygdalohippocampectomy peaks while accessing the temporal horn through its roof by opening the inferior limiting sulcus of the insula. In this prospective study, we sought to evaluate and identify the incidence of visual field deficits in a homogeneous group of patients who had temporal lobe epilepsy with hippocampal sclerosis and who underwent transsylvian selective amygdalohippocampectomy. METHODS We studied 30 patients who were referred for epilepsy surgery for intractable complex partial and/or secondary generalized seizures and evaluated according to a noninvasive protocol. All patients underwent selective amygdalohippocampectomy for temporal lobe epilepsy with hippocampal sclerosis using the standard tr...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/80025266" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="c191fcce987af75d065171ce840812e4" rel="nofollow" data-download="{"attachment_id":86544159,"asset_id":80025266,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/86544159/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="210213845" href="https://independent.academia.edu/OzlemUyanik">Ozlem Uyanik</a><script data-card-contents-for-user="210213845" type="text/json">{"id":210213845,"first_name":"Ozlem","last_name":"Uyanik","domain_name":"independent","page_name":"OzlemUyanik","display_name":"Ozlem Uyanik","profile_url":"https://independent.academia.edu/OzlemUyanik?f_ri=57557","photo":"https://0.academia-photos.com/210213845/84002392/72629772/s65_ozlem.uyanik.png"}</script></span></span></li><li class="js-paper-rank-work_80025266 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="80025266"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 80025266, container: ".js-paper-rank-work_80025266", }); });</script></li><li class="js-percentile-work_80025266 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 80025266; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_80025266"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_80025266 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="80025266"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 80025266; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=80025266]").text(description); $(".js-view-count-work_80025266").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_80025266").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="80025266"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">15</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="647" rel="nofollow" href="https://www.academia.edu/Documents/in/Surgery">Surgery</a>, <script data-card-contents-for-ri="647" type="text/json">{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="650" rel="nofollow" href="https://www.academia.edu/Documents/in/Neurosurgery">Neurosurgery</a>, <script data-card-contents-for-ri="650" type="text/json">{"id":650,"name":"Neurosurgery","url":"https://www.academia.edu/Documents/in/Neurosurgery?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="1328" rel="nofollow" href="https://www.academia.edu/Documents/in/Radiation">Radiation</a>, <script data-card-contents-for-ri="1328" type="text/json">{"id":1328,"name":"Radiation","url":"https://www.academia.edu/Documents/in/Radiation?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="7648" rel="nofollow" href="https://www.academia.edu/Documents/in/Epilepsy">Epilepsy</a><script data-card-contents-for-ri="7648" type="text/json">{"id":7648,"name":"Epilepsy","url":"https://www.academia.edu/Documents/in/Epilepsy?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=80025266]'), work: {"id":80025266,"title":"Visual Field Defects in Selective Amygdalohippocampectomy for Hippocampal Sclerosis","created_at":"2022-05-27T01:42:00.738-07:00","url":"https://www.academia.edu/80025266/Visual_Field_Defects_in_Selective_Amygdalohippocampectomy_for_Hippocampal_Sclerosis?f_ri=57557","dom_id":"work_80025266","summary":"OBJECTIVE Meyer\u0026#39;s loop, the most vulnerable part of the optic radiations during approaches to the temporomedial region, extends to the tip of the temporal horn and is often encountered in epilepsy surgery. The risk of damaging Meyer\u0026#39;s loop during transsylvian selective amygdalohippocampectomy peaks while accessing the temporal horn through its roof by opening the inferior limiting sulcus of the insula. In this prospective study, we sought to evaluate and identify the incidence of visual field deficits in a homogeneous group of patients who had temporal lobe epilepsy with hippocampal sclerosis and who underwent transsylvian selective amygdalohippocampectomy. METHODS We studied 30 patients who were referred for epilepsy surgery for intractable complex partial and/or secondary generalized seizures and evaluated according to a noninvasive protocol. All patients underwent selective amygdalohippocampectomy for temporal lobe epilepsy with hippocampal sclerosis using the standard tr...","downloadable_attachments":[{"id":86544159,"asset_id":80025266,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":210213845,"first_name":"Ozlem","last_name":"Uyanik","domain_name":"independent","page_name":"OzlemUyanik","display_name":"Ozlem Uyanik","profile_url":"https://independent.academia.edu/OzlemUyanik?f_ri=57557","photo":"https://0.academia-photos.com/210213845/84002392/72629772/s65_ozlem.uyanik.png"}],"research_interests":[{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery?f_ri=57557","nofollow":true},{"id":650,"name":"Neurosurgery","url":"https://www.academia.edu/Documents/in/Neurosurgery?f_ri=57557","nofollow":true},{"id":1328,"name":"Radiation","url":"https://www.academia.edu/Documents/in/Radiation?f_ri=57557","nofollow":true},{"id":7648,"name":"Epilepsy","url":"https://www.academia.edu/Documents/in/Epilepsy?f_ri=57557","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=57557"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=57557"},{"id":54589,"name":"Anatomy","url":"https://www.academia.edu/Documents/in/Anatomy?f_ri=57557"},{"id":57556,"name":"Hippocampus","url":"https://www.academia.edu/Documents/in/Hippocampus?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=57557"},{"id":159962,"name":"Amygdala","url":"https://www.academia.edu/Documents/in/Amygdala?f_ri=57557"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=57557"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=57557"},{"id":2753977,"name":"Hippocampal Sclerosis","url":"https://www.academia.edu/Documents/in/Hippocampal_Sclerosis?f_ri=57557"},{"id":2970981,"name":"Sclerosis","url":"https://www.academia.edu/Documents/in/Sclerosis?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_65696915" data-work_id="65696915" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/65696915/Capgras_syndrome_a_novel_probe_for_understanding_the_neural_representation_of_the_identity_and_familiarity_of_persons">Capgras syndrome: a novel probe for understanding the neural representation of the identity and familiarity of persons</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Patients with Capgras syndrome regard people whom they know well such as their parents or siblings as imposters. Here we describe a case (DS) of this syndrome who presents several novel features. DS was unusual in that his delusion was... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_65696915" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Patients with Capgras syndrome regard people whom they know well such as their parents or siblings as imposters. Here we describe a case (DS) of this syndrome who presents several novel features. DS was unusual in that his delusion was modality–specific: he claimed that his parents were imposters when he was looking at them but not when speaking to them on the telephone. Unlike normals, DS&#x27;s skin conductance responses to photographs of familiar people, including his parents, were not larger in magnitude than ...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/65696915" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="eafaa1521006509d725c824d57203290" rel="nofollow" data-download="{"attachment_id":77181311,"asset_id":65696915,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/77181311/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="128667263" href="https://independent.academia.edu/GabrielaPereira183">Gabriela Pereira</a><script data-card-contents-for-user="128667263" type="text/json">{"id":128667263,"first_name":"Gabriela","last_name":"Pereira","domain_name":"independent","page_name":"GabrielaPereira183","display_name":"Gabriela Pereira","profile_url":"https://independent.academia.edu/GabrielaPereira183?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_65696915 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="65696915"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 65696915, container: ".js-paper-rank-work_65696915", }); });</script></li><li class="js-percentile-work_65696915 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 65696915; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_65696915"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_65696915 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="65696915"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65696915; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=65696915]").text(description); $(".js-view-count-work_65696915").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_65696915").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="65696915"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">16</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="1589" rel="nofollow" href="https://www.academia.edu/Documents/in/Photography">Photography</a>, <script data-card-contents-for-ri="1589" type="text/json">{"id":1589,"name":"Photography","url":"https://www.academia.edu/Documents/in/Photography?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="32361" rel="nofollow" href="https://www.academia.edu/Documents/in/Episodic_Memory">Episodic Memory</a><script data-card-contents-for-ri="32361" type="text/json">{"id":32361,"name":"Episodic Memory","url":"https://www.academia.edu/Documents/in/Episodic_Memory?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=65696915]'), work: {"id":65696915,"title":"Capgras syndrome: a novel probe for understanding the neural representation of the identity and familiarity of persons","created_at":"2021-12-23T07:01:30.646-08:00","url":"https://www.academia.edu/65696915/Capgras_syndrome_a_novel_probe_for_understanding_the_neural_representation_of_the_identity_and_familiarity_of_persons?f_ri=57557","dom_id":"work_65696915","summary":"Patients with Capgras syndrome regard people whom they know well such as their parents or siblings as imposters. Here we describe a case (DS) of this syndrome who presents several novel features. DS was unusual in that his delusion was modality–specific: he claimed that his parents were imposters when he was looking at them but not when speaking to them on the telephone. Unlike normals, DS\u0026#x27;s skin conductance responses to photographs of familiar people, including his parents, were not larger in magnitude than ...","downloadable_attachments":[{"id":77181311,"asset_id":65696915,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":128667263,"first_name":"Gabriela","last_name":"Pereira","domain_name":"independent","page_name":"GabrielaPereira183","display_name":"Gabriela Pereira","profile_url":"https://independent.academia.edu/GabrielaPereira183?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true},{"id":1589,"name":"Photography","url":"https://www.academia.edu/Documents/in/Photography?f_ri=57557","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=57557","nofollow":true},{"id":32361,"name":"Episodic Memory","url":"https://www.academia.edu/Documents/in/Episodic_Memory?f_ri=57557","nofollow":true},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=57557"},{"id":52176,"name":"Brain Mapping","url":"https://www.academia.edu/Documents/in/Brain_Mapping?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":66843,"name":"Judgment","url":"https://www.academia.edu/Documents/in/Judgment?f_ri=57557"},{"id":100928,"name":"Face processing","url":"https://www.academia.edu/Documents/in/Face_processing?f_ri=57557"},{"id":108586,"name":"Gaze Direction","url":"https://www.academia.edu/Documents/in/Gaze_Direction?f_ri=57557"},{"id":187795,"name":"Skin conductance response","url":"https://www.academia.edu/Documents/in/Skin_conductance_response?f_ri=57557"},{"id":384955,"name":"Capgras Syndrome","url":"https://www.academia.edu/Documents/in/Capgras_Syndrome?f_ri=57557"},{"id":460445,"name":"Nuclear Family","url":"https://www.academia.edu/Documents/in/Nuclear_Family?f_ri=57557"},{"id":494840,"name":"Limbic System","url":"https://www.academia.edu/Documents/in/Limbic_System?f_ri=57557"},{"id":3763225,"name":"Medical and Health Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences?f_ri=57557"},{"id":4002452,"name":"Accidents Traffic","url":"https://www.academia.edu/Documents/in/Accidents_Traffic?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_65536064" data-work_id="65536064" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/65536064/Music_training_and_mental_imagery_ability">Music training and mental imagery ability</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Neuroimaging studies have suggested that the auditory cortex is involved in music processing as well as in auditory imagery. We hypothesized that music training may be associated with improved auditory imagery ability. In this study,... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_65536064" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Neuroimaging studies have suggested that the auditory cortex is involved in music processing as well as in auditory imagery. We hypothesized that music training may be associated with improved auditory imagery ability. In this study, performance of musically trained and musically naive subjects was compared on: (1) a musical mental imagery task (in which subjects had to mentally compare pitches of notes corresponding to lyrics taken from familiar songs); (2) a non-musical auditory imagery task (in which subjects had to mentally compare the acoustic characteristics of everyday sounds); and (3) a comparable measure of visual imagery (in which subjects had to mentally compare visual forms of objects). The musically trained group did not only perform better on the musical imagery task, but also outperformed musically naive subjects on the non-musical auditory imagery task. In contrast, the two groups did not differ on the visual imagery task. This finding is discussed in relation to theoretical proposals about music processing and brain activity.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/65536064" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="f0eb3079e168bd0c028cd26977a91e75" rel="nofollow" data-download="{"attachment_id":77088259,"asset_id":65536064,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/77088259/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="211047635" href="https://rug.academia.edu/AndreAleman">Andre Aleman</a><script data-card-contents-for-user="211047635" type="text/json">{"id":211047635,"first_name":"Andre","last_name":"Aleman","domain_name":"rug","page_name":"AndreAleman","display_name":"Andre Aleman","profile_url":"https://rug.academia.edu/AndreAleman?f_ri=57557","photo":"https://0.academia-photos.com/211047635/70513894/58934724/s65_andre.aleman.png"}</script></span></span></li><li class="js-paper-rank-work_65536064 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="65536064"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 65536064, container: ".js-paper-rank-work_65536064", }); });</script></li><li class="js-percentile-work_65536064 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 65536064; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_65536064"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_65536064 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="65536064"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65536064; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=65536064]").text(description); $(".js-view-count-work_65536064").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_65536064").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="65536064"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">16</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="237" rel="nofollow" href="https://www.academia.edu/Documents/in/Cognitive_Science">Cognitive Science</a>, <script data-card-contents-for-ri="237" type="text/json">{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="671" rel="nofollow" href="https://www.academia.edu/Documents/in/Music">Music</a>, <script data-card-contents-for-ri="671" type="text/json">{"id":671,"name":"Music","url":"https://www.academia.edu/Documents/in/Music?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="867" rel="nofollow" href="https://www.academia.edu/Documents/in/Perception">Perception</a><script data-card-contents-for-ri="867" type="text/json">{"id":867,"name":"Perception","url":"https://www.academia.edu/Documents/in/Perception?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=65536064]'), work: {"id":65536064,"title":"Music training and mental imagery ability","created_at":"2021-12-22T09:43:53.872-08:00","url":"https://www.academia.edu/65536064/Music_training_and_mental_imagery_ability?f_ri=57557","dom_id":"work_65536064","summary":"Neuroimaging studies have suggested that the auditory cortex is involved in music processing as well as in auditory imagery. We hypothesized that music training may be associated with improved auditory imagery ability. In this study, performance of musically trained and musically naive subjects was compared on: (1) a musical mental imagery task (in which subjects had to mentally compare pitches of notes corresponding to lyrics taken from familiar songs); (2) a non-musical auditory imagery task (in which subjects had to mentally compare the acoustic characteristics of everyday sounds); and (3) a comparable measure of visual imagery (in which subjects had to mentally compare visual forms of objects). The musically trained group did not only perform better on the musical imagery task, but also outperformed musically naive subjects on the non-musical auditory imagery task. In contrast, the two groups did not differ on the visual imagery task. This finding is discussed in relation to theoretical proposals about music processing and brain activity.","downloadable_attachments":[{"id":77088259,"asset_id":65536064,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":211047635,"first_name":"Andre","last_name":"Aleman","domain_name":"rug","page_name":"AndreAleman","display_name":"Andre Aleman","profile_url":"https://rug.academia.edu/AndreAleman?f_ri=57557","photo":"https://0.academia-photos.com/211047635/70513894/58934724/s65_andre.aleman.png"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true},{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true},{"id":671,"name":"Music","url":"https://www.academia.edu/Documents/in/Music?f_ri=57557","nofollow":true},{"id":867,"name":"Perception","url":"https://www.academia.edu/Documents/in/Perception?f_ri=57557","nofollow":true},{"id":3031,"name":"Auditory Perception","url":"https://www.academia.edu/Documents/in/Auditory_Perception?f_ri=57557"},{"id":4212,"name":"Cognition","url":"https://www.academia.edu/Documents/in/Cognition?f_ri=57557"},{"id":15838,"name":"Imagination","url":"https://www.academia.edu/Documents/in/Imagination?f_ri=57557"},{"id":23890,"name":"Comparative Study","url":"https://www.academia.edu/Documents/in/Comparative_Study?f_ri=57557"},{"id":43774,"name":"Learning","url":"https://www.academia.edu/Documents/in/Learning?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":66337,"name":"Visual Imagery","url":"https://www.academia.edu/Documents/in/Visual_Imagery?f_ri=57557"},{"id":66338,"name":"Mental Imagery","url":"https://www.academia.edu/Documents/in/Mental_Imagery?f_ri=57557"},{"id":452621,"name":"Neuropsychologia","url":"https://www.academia.edu/Documents/in/Neuropsychologia?f_ri=57557"},{"id":723371,"name":"Auditory Cortex","url":"https://www.academia.edu/Documents/in/Auditory_Cortex?f_ri=57557"},{"id":953027,"name":"Auditory Imagery","url":"https://www.academia.edu/Documents/in/Auditory_Imagery?f_ri=57557"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_2449847" data-work_id="2449847" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/2449847/Ventricular_Enlargement_in_Poor_Outcome_Schizophrenia">Ventricular Enlargement in Poor-Outcome Schizophrenia</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Background: A subset of patients with schizophrenia, defined on the basis of longitudinal deficits in self-care, may show a classic (“Kraepelinian”) degenerative course. An independent validator of the phenomenologically defined... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_2449847" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Background: A subset of patients with schizophrenia, defined on the basis of longitudinal deficits in self-care, may show a classic (“Kraepelinian”) degenerative course. An independent validator of the phenomenologically defined Kraepelinian subtype might be provided by a structural indicator of possible brain degeneration: ventricular size as measured by computed tomography (CT).Methods: To examine whether Kraepelinian patients would show a differential increase in ventricular size over time, two CT scans were conducted at intervals separated by >4 years, an average of 5 years. Fifty-three male patients with DSM-III-R diagnoses of chronic schizophrenia were subdivided into Kraepelinian (n = 22; mean age = 42 ± 8.6 years) and non-Kraepelinian (n = 31; mean age = 38 ± 12.2 years) subgroups. Kraepelinian patients were defined on the basis of longitudinal criteria: >5 years of complete dependence on others for life necessities and care, lack of employment, and sustained symptomatology. Thirteen normal elderly volunteers (mean age = 60 ± 17.8) were also scanned at 4-year intervals. CT measurements were made by raters without knowledge of subgroup membership. A semiautomated computer program was used to trace the anterior horn, lateral ventricles, and temporal horns for each slice level on which they were clearly seen.Results: The ventricles showed a bilateral increase in size over the 4-year interval in the Kraepelinian subgroup, more marked in the left hemisphere than the right. By contrast, neither the non-Kraepelinian subgroup nor the normal volunteers showed significant CT changes from scan 1 to scan 2.Conclusions: Thus, the longitudinal dysfunctions in self-care that characterize the Kraepelinian patients were associated with an independent indicator of brain abnormality.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/2449847" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="84bce0c66d5ef95995992ddd80ba9209" rel="nofollow" data-download="{"attachment_id":50619489,"asset_id":2449847,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/50619489/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="3190936" href="https://ucsd.academia.edu/MonteBuchsbaum">Monte Buchsbaum</a><script data-card-contents-for-user="3190936" type="text/json">{"id":3190936,"first_name":"Monte","last_name":"Buchsbaum","domain_name":"ucsd","page_name":"MonteBuchsbaum","display_name":"Monte Buchsbaum","profile_url":"https://ucsd.academia.edu/MonteBuchsbaum?f_ri=57557","photo":"https://0.academia-photos.com/3190936/1049535/1310739/s65_monte.buchsbaum.jpg"}</script></span></span></li><li class="js-paper-rank-work_2449847 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="2449847"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 2449847, container: ".js-paper-rank-work_2449847", }); 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$(".js-view-count[data-work-id=2449847]").text(description); $(".js-view-count-work_2449847").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_2449847").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="2449847"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">22</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="1648" rel="nofollow" href="https://www.academia.edu/Documents/in/Computed_Tomography">Computed Tomography</a>, <script data-card-contents-for-ri="1648" type="text/json">{"id":1648,"name":"Computed Tomography","url":"https://www.academia.edu/Documents/in/Computed_Tomography?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="3227" rel="nofollow" href="https://www.academia.edu/Documents/in/Schizophrenia">Schizophrenia</a>, <script data-card-contents-for-ri="3227" type="text/json">{"id":3227,"name":"Schizophrenia","url":"https://www.academia.edu/Documents/in/Schizophrenia?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="10882" rel="nofollow" href="https://www.academia.edu/Documents/in/Evolution">Evolution</a>, <script data-card-contents-for-ri="10882" type="text/json">{"id":10882,"name":"Evolution","url":"https://www.academia.edu/Documents/in/Evolution?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="37848" rel="nofollow" href="https://www.academia.edu/Documents/in/Neurodegenerative_Diseases">Neurodegenerative Diseases</a><script data-card-contents-for-ri="37848" type="text/json">{"id":37848,"name":"Neurodegenerative Diseases","url":"https://www.academia.edu/Documents/in/Neurodegenerative_Diseases?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=2449847]'), work: {"id":2449847,"title":"Ventricular Enlargement in Poor-Outcome Schizophrenia","created_at":"2013-01-23T02:48:50.905-08:00","url":"https://www.academia.edu/2449847/Ventricular_Enlargement_in_Poor_Outcome_Schizophrenia?f_ri=57557","dom_id":"work_2449847","summary":"Background: A subset of patients with schizophrenia, defined on the basis of longitudinal deficits in self-care, may show a classic (“Kraepelinian”) degenerative course. An independent validator of the phenomenologically defined Kraepelinian subtype might be provided by a structural indicator of possible brain degeneration: ventricular size as measured by computed tomography (CT).Methods: To examine whether Kraepelinian patients would show a differential increase in ventricular size over time, two CT scans were conducted at intervals separated by \u003e4 years, an average of 5 years. Fifty-three male patients with DSM-III-R diagnoses of chronic schizophrenia were subdivided into Kraepelinian (n = 22; mean age = 42 ± 8.6 years) and non-Kraepelinian (n = 31; mean age = 38 ± 12.2 years) subgroups. Kraepelinian patients were defined on the basis of longitudinal criteria: \u003e5 years of complete dependence on others for life necessities and care, lack of employment, and sustained symptomatology. Thirteen normal elderly volunteers (mean age = 60 ± 17.8) were also scanned at 4-year intervals. CT measurements were made by raters without knowledge of subgroup membership. A semiautomated computer program was used to trace the anterior horn, lateral ventricles, and temporal horns for each slice level on which they were clearly seen.Results: The ventricles showed a bilateral increase in size over the 4-year interval in the Kraepelinian subgroup, more marked in the left hemisphere than the right. By contrast, neither the non-Kraepelinian subgroup nor the normal volunteers showed significant CT changes from scan 1 to scan 2.Conclusions: Thus, the longitudinal dysfunctions in self-care that characterize the Kraepelinian patients were associated with an independent indicator of brain abnormality.","downloadable_attachments":[{"id":50619489,"asset_id":2449847,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":3190936,"first_name":"Monte","last_name":"Buchsbaum","domain_name":"ucsd","page_name":"MonteBuchsbaum","display_name":"Monte Buchsbaum","profile_url":"https://ucsd.academia.edu/MonteBuchsbaum?f_ri=57557","photo":"https://0.academia-photos.com/3190936/1049535/1310739/s65_monte.buchsbaum.jpg"}],"research_interests":[{"id":1648,"name":"Computed Tomography","url":"https://www.academia.edu/Documents/in/Computed_Tomography?f_ri=57557","nofollow":true},{"id":3227,"name":"Schizophrenia","url":"https://www.academia.edu/Documents/in/Schizophrenia?f_ri=57557","nofollow":true},{"id":10882,"name":"Evolution","url":"https://www.academia.edu/Documents/in/Evolution?f_ri=57557","nofollow":true},{"id":37848,"name":"Neurodegenerative Diseases","url":"https://www.academia.edu/Documents/in/Neurodegenerative_Diseases?f_ri=57557","nofollow":true},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=57557"},{"id":49600,"name":"Biological Psychiatry","url":"https://www.academia.edu/Documents/in/Biological_Psychiatry?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain?f_ri=57557"},{"id":97269,"name":"Chronic Disease","url":"https://www.academia.edu/Documents/in/Chronic_Disease?f_ri=57557"},{"id":117643,"name":"Biological","url":"https://www.academia.edu/Documents/in/Biological?f_ri=57557"},{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies?f_ri=57557"},{"id":209591,"name":"Ct Scan","url":"https://www.academia.edu/Documents/in/Ct_Scan?f_ri=57557"},{"id":258979,"name":"Computer Program","url":"https://www.academia.edu/Documents/in/Computer_Program?f_ri=57557"},{"id":280458,"name":"Brain atrophy","url":"https://www.academia.edu/Documents/in/Brain_atrophy?f_ri=57557"},{"id":330953,"name":"Longitudinal Studies","url":"https://www.academia.edu/Documents/in/Longitudinal_Studies?f_ri=57557"},{"id":357850,"name":"Atrophy","url":"https://www.academia.edu/Documents/in/Atrophy?f_ri=57557"},{"id":436755,"name":"Degeneration","url":"https://www.academia.edu/Documents/in/Degeneration?f_ri=57557"},{"id":489727,"name":"Prognosis","url":"https://www.academia.edu/Documents/in/Prognosis?f_ri=57557"},{"id":810789,"name":"Left Hemisphere","url":"https://www.academia.edu/Documents/in/Left_Hemisphere?f_ri=57557"},{"id":959921,"name":"X ray Computed Tomography","url":"https://www.academia.edu/Documents/in/X_ray_Computed_Tomography?f_ri=57557"},{"id":1627527,"name":"Cognition disorders","url":"https://www.academia.edu/Documents/in/Cognition_disorders?f_ri=57557"},{"id":2467529,"name":"Psychiatric Status Rating Scales","url":"https://www.academia.edu/Documents/in/Psychiatric_Status_Rating_Scales?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_3726366" data-work_id="3726366" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/3726366/Brain_anatomy_and_development_in_autism_review_of_structural_MRI_studies">Brain anatomy and development in autism: review of structural MRI studies</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Autism is a neurodevelopmental disorder that severely disrupts social and cognitive functions. MRI is the method of choice for in vivo and non-invasively investigating human brain morphology in children and adolescents. The authors... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_3726366" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Autism is a neurodevelopmental disorder that severely disrupts social and cognitive functions. MRI is the method of choice for in vivo and non-invasively investigating human brain morphology in children and adolescents. The authors reviewed structural MRI studies that investigated structural brain anatomy and development in autistic patients. All original MRI research papers involving autistic patients, published from 1966 to May 2003, were reviewed in order to elucidate brain anatomy and development of autism and rated for completeness using a 12-item check-list. Increased total brain, parieto-temporal lobe, and cerebellar hemisphere volumes were the most replicated abnormalities in autism. Interestingly, recent findings suggested that the size of amygdala, hippocampus, and corpus callosum may also be abnormal. It is conceivable that abnormalities in neural network involving fronto-temporo-parietal cortex, limbic system, and cerebellum may underlie the pathophysiology of autism, and that such changes could result from abnormal brain development during early life. Nonetheless, available MRI studies were often conflicting and could have been limited by methodological issues. Future MRI investigations should include well-characterized groups of autistic and matched healthy individuals, while taking into consideration confounding factors such as IQ, and socioeconomic status.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/3726366" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="681072ee3bf1f2d59acc05fad68b7544" rel="nofollow" data-download="{"attachment_id":33023816,"asset_id":3726366,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/33023816/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="3433017" href="https://unimi.academia.edu/paolobrambilla">paolo brambilla</a><script data-card-contents-for-user="3433017" type="text/json">{"id":3433017,"first_name":"paolo","last_name":"brambilla","domain_name":"unimi","page_name":"paolobrambilla","display_name":"paolo brambilla","profile_url":"https://unimi.academia.edu/paolobrambilla?f_ri=57557","photo":"https://0.academia-photos.com/3433017/1168070/4257998/s65_paolo.brambilla.jpg"}</script></span></span></li><li class="js-paper-rank-work_3726366 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="3726366"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 3726366, container: ".js-paper-rank-work_3726366", }); });</script></li><li class="js-percentile-work_3726366 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 3726366; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_3726366"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_3726366 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="3726366"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 3726366; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=3726366]").text(description); $(".js-view-count-work_3726366").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_3726366").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="3726366"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">18</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="237" rel="nofollow" href="https://www.academia.edu/Documents/in/Cognitive_Science">Cognitive Science</a>, <script data-card-contents-for-ri="237" type="text/json">{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26066" rel="nofollow" href="https://www.academia.edu/Documents/in/Neural_Network">Neural Network</a>, <script data-card-contents-for-ri="26066" type="text/json">{"id":26066,"name":"Neural Network","url":"https://www.academia.edu/Documents/in/Neural_Network?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="29538" rel="nofollow" href="https://www.academia.edu/Documents/in/Brain_development">Brain development</a><script data-card-contents-for-ri="29538" type="text/json">{"id":29538,"name":"Brain development","url":"https://www.academia.edu/Documents/in/Brain_development?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=3726366]'), work: {"id":3726366,"title":"Brain anatomy and development in autism: review of structural MRI studies","created_at":"2013-06-16T20:05:37.585-07:00","url":"https://www.academia.edu/3726366/Brain_anatomy_and_development_in_autism_review_of_structural_MRI_studies?f_ri=57557","dom_id":"work_3726366","summary":"Autism is a neurodevelopmental disorder that severely disrupts social and cognitive functions. MRI is the method of choice for in vivo and non-invasively investigating human brain morphology in children and adolescents. The authors reviewed structural MRI studies that investigated structural brain anatomy and development in autistic patients. All original MRI research papers involving autistic patients, published from 1966 to May 2003, were reviewed in order to elucidate brain anatomy and development of autism and rated for completeness using a 12-item check-list. Increased total brain, parieto-temporal lobe, and cerebellar hemisphere volumes were the most replicated abnormalities in autism. Interestingly, recent findings suggested that the size of amygdala, hippocampus, and corpus callosum may also be abnormal. It is conceivable that abnormalities in neural network involving fronto-temporo-parietal cortex, limbic system, and cerebellum may underlie the pathophysiology of autism, and that such changes could result from abnormal brain development during early life. Nonetheless, available MRI studies were often conflicting and could have been limited by methodological issues. Future MRI investigations should include well-characterized groups of autistic and matched healthy individuals, while taking into consideration confounding factors such as IQ, and socioeconomic status.","downloadable_attachments":[{"id":33023816,"asset_id":3726366,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":3433017,"first_name":"paolo","last_name":"brambilla","domain_name":"unimi","page_name":"paolobrambilla","display_name":"paolo brambilla","profile_url":"https://unimi.academia.edu/paolobrambilla?f_ri=57557","photo":"https://0.academia-photos.com/3433017/1168070/4257998/s65_paolo.brambilla.jpg"}],"research_interests":[{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":26066,"name":"Neural Network","url":"https://www.academia.edu/Documents/in/Neural_Network?f_ri=57557","nofollow":true},{"id":29538,"name":"Brain development","url":"https://www.academia.edu/Documents/in/Brain_development?f_ri=57557","nofollow":true},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain?f_ri=57557"},{"id":65614,"name":"Corpus Callosum","url":"https://www.academia.edu/Documents/in/Corpus_Callosum?f_ri=57557"},{"id":123274,"name":"Parietal Cortex","url":"https://www.academia.edu/Documents/in/Parietal_Cortex?f_ri=57557"},{"id":142311,"name":"Research Paper","url":"https://www.academia.edu/Documents/in/Research_Paper?f_ri=57557"},{"id":203010,"name":"Human Brain","url":"https://www.academia.edu/Documents/in/Human_Brain?f_ri=57557"},{"id":226330,"name":"Socioeconomic 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{"id":12718278,"title":"Social Network Size Affects Neural Circuits in Macaques","created_at":"2015-06-01T03:55:04.861-07:00","url":"https://www.academia.edu/12718278/Social_Network_Size_Affects_Neural_Circuits_in_Macaques?f_ri=57557","dom_id":"work_12718278","summary":null,"downloadable_attachments":[{"id":45981409,"asset_id":12718278,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":31748637,"first_name":"Jérôme","last_name":"Sallet","domain_name":"independent","page_name":"JérômeSallet","display_name":"Jérôme Sallet","profile_url":"https://independent.academia.edu/J%C3%A9r%C3%B4meSallet?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":6200,"name":"Magnetic Resonance 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pathways","url":"https://www.academia.edu/Documents/in/Neural_pathways?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_12728611" data-work_id="12728611" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/12728611/Enhanced_brain_responsiveness_during_active_emotional_face_processing_in_obsessive_compulsive_disorder">Enhanced brain responsiveness during active emotional face processing in obsessive compulsive disorder</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objectives. The abnormal processing of emotional stimuli is common to a variety of psychiatric disorders. Specifi cally, patients with prominent anxiety symptoms generally overreact to emotional cues, which has been linked to increased... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_12728611" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objectives. The abnormal processing of emotional stimuli is common to a variety of psychiatric disorders. Specifi cally, patients with prominent anxiety symptoms generally overreact to emotional cues, which has been linked to increased amygdala activation. However, in OCD, enhanced responses are predominantly obtained using disease-specifi c stimuli and preferentially involve frontostriatal systems. Methods. We assessed 21 OCD patients and 21 healthy controls with fMRI during an emotional face-processing paradigm involving active response generation to test for alterations in both brain activation and task-induced functional connectivity of the frontal cortex, the amygdala and the fusiform face area. Results. OCD patients showed signifi cantly greater activation of " face-processing " regions including the amygdala, fusiform gyrus and dorsolateral prefrontal cortex. The reciprocal connectivity between face-processing regions was enhanced in OCD. Importantly, we detected signifi cant correlations between patients ' clinical symptom severity and both task-related region activation and network functional connectivity. Conclusions. The results suggest that OCD patients may show enhanced brain responsiveness during emotional face-processing when tasks involve active response generation. Our fi ndings diverge from previously described alterations in anxiety disorders, as patients showed enhanced amygdala-prefrontal connectivity as opposed to negative reciprocal interaction. This pattern would appear to be disorder-specifi c and was signifi cantly related to obsessive-compulsive symptom severity.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/12728611" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a96caae8452d0d6ee0fd18750ac62fea" rel="nofollow" data-download="{"attachment_id":45976240,"asset_id":12728611,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45976240/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="31760076" href="https://independent.academia.edu/Narc%C3%ADsCardoner">Narcís Cardoner</a><script data-card-contents-for-user="31760076" type="text/json">{"id":31760076,"first_name":"Narcís","last_name":"Cardoner","domain_name":"independent","page_name":"NarcísCardoner","display_name":"Narcís Cardoner","profile_url":"https://independent.academia.edu/Narc%C3%ADsCardoner?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_12728611 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="12728611"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 12728611, container: ".js-paper-rank-work_12728611", }); 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$(".js-view-count[data-work-id=12728611]").text(description); $(".js-view-count-work_12728611").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_12728611").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="12728611"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">17</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="254" rel="nofollow" href="https://www.academia.edu/Documents/in/Emotion">Emotion</a>, <script data-card-contents-for-ri="254" type="text/json">{"id":254,"name":"Emotion","url":"https://www.academia.edu/Documents/in/Emotion?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="21269" rel="nofollow" href="https://www.academia.edu/Documents/in/Facial_expression">Facial expression</a>, <script data-card-contents-for-ri="21269" type="text/json">{"id":21269,"name":"Facial expression","url":"https://www.academia.edu/Documents/in/Facial_expression?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="28576" rel="nofollow" href="https://www.academia.edu/Documents/in/Prefrontal_Cortex">Prefrontal Cortex</a><script data-card-contents-for-ri="28576" type="text/json">{"id":28576,"name":"Prefrontal Cortex","url":"https://www.academia.edu/Documents/in/Prefrontal_Cortex?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=12728611]'), work: {"id":12728611,"title":"Enhanced brain responsiveness during active emotional face processing in obsessive compulsive disorder","created_at":"2015-06-01T10:20:54.631-07:00","url":"https://www.academia.edu/12728611/Enhanced_brain_responsiveness_during_active_emotional_face_processing_in_obsessive_compulsive_disorder?f_ri=57557","dom_id":"work_12728611","summary":"Objectives. The abnormal processing of emotional stimuli is common to a variety of psychiatric disorders. Specifi cally, patients with prominent anxiety symptoms generally overreact to emotional cues, which has been linked to increased amygdala activation. However, in OCD, enhanced responses are predominantly obtained using disease-specifi c stimuli and preferentially involve frontostriatal systems. Methods. We assessed 21 OCD patients and 21 healthy controls with fMRI during an emotional face-processing paradigm involving active response generation to test for alterations in both brain activation and task-induced functional connectivity of the frontal cortex, the amygdala and the fusiform face area. Results. OCD patients showed signifi cantly greater activation of \" face-processing \" regions including the amygdala, fusiform gyrus and dorsolateral prefrontal cortex. The reciprocal connectivity between face-processing regions was enhanced in OCD. Importantly, we detected signifi cant correlations between patients ' clinical symptom severity and both task-related region activation and network functional connectivity. Conclusions. The results suggest that OCD patients may show enhanced brain responsiveness during emotional face-processing when tasks involve active response generation. Our fi ndings diverge from previously described alterations in anxiety disorders, as patients showed enhanced amygdala-prefrontal connectivity as opposed to negative reciprocal interaction. This pattern would appear to be disorder-specifi c and was signifi cantly related to obsessive-compulsive symptom severity.","downloadable_attachments":[{"id":45976240,"asset_id":12728611,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":31760076,"first_name":"Narcís","last_name":"Cardoner","domain_name":"independent","page_name":"NarcísCardoner","display_name":"Narcís Cardoner","profile_url":"https://independent.academia.edu/Narc%C3%ADsCardoner?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":254,"name":"Emotion","url":"https://www.academia.edu/Documents/in/Emotion?f_ri=57557","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":21269,"name":"Facial expression","url":"https://www.academia.edu/Documents/in/Facial_expression?f_ri=57557","nofollow":true},{"id":28576,"name":"Prefrontal Cortex","url":"https://www.academia.edu/Documents/in/Prefrontal_Cortex?f_ri=57557","nofollow":true},{"id":42162,"name":"Emotions","url":"https://www.academia.edu/Documents/in/Emotions?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain?f_ri=57557"},{"id":73606,"name":"World","url":"https://www.academia.edu/Documents/in/World?f_ri=57557"},{"id":100946,"name":"Functional Imaging","url":"https://www.academia.edu/Documents/in/Functional_Imaging?f_ri=57557"},{"id":119379,"name":"Obsessive Compulsive Disorder","url":"https://www.academia.edu/Documents/in/Obsessive_Compulsive_Disorder?f_ri=57557"},{"id":119665,"name":"Reaction Time","url":"https://www.academia.edu/Documents/in/Reaction_Time?f_ri=57557"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=57557"},{"id":159962,"name":"Amygdala","url":"https://www.academia.edu/Documents/in/Amygdala?f_ri=57557"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=57557"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=57557"},{"id":1257483,"name":"Frontal Lobe","url":"https://www.academia.edu/Documents/in/Frontal_Lobe?f_ri=57557"},{"id":1819399,"name":"Case Control Studies","url":"https://www.academia.edu/Documents/in/Case_Control_Studies?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_25509266" data-work_id="25509266" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/25509266/The_Impact_of_Cerebral_Source_Area_and_Synchrony_on_Recording_Scalp_Electroencephalography_Ictal_Patterns">The Impact of Cerebral Source Area and Synchrony on Recording Scalp Electroencephalography Ictal Patterns</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Purpose: To determine the cerebral electroencephalography (EEG) substrates of scalp EEG seizure patterns, such as source area and synchrony, and in so doing assess the limitations of scalp seizure recording in the localization of seizure... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_25509266" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Purpose: To determine the cerebral electroencephalography (EEG) substrates of scalp EEG seizure patterns, such as source area and synchrony, and in so doing assess the limitations of scalp seizure recording in the localization of seizure onset zones in patients with temporal lobe epilepsy. Methods: We recorded simultaneously 26 channels of scalp EEG with subtemporal supplementary electrodes and 46-98 channels of intracranial EEG in presurgical candidates with temporal lobe epilepsy. We correlated intracranial EEG source area and synchrony at seizure onset with the corresponding scalp EEG. Eighty-six simultaneous intracranial-and scalp-recorded seizures from 23 patients were evaluated. Results: Thirty-four intracranial ictal discharges (40%) from 9 patients (39%) had sufficient cortical source area (namely > 10 cm 2 ) and synchrony at seizure onset to produce a simultaneous or nearly simultaneous focal scalp EEG ictal pattern.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/25509266" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="5941f76d629b86c1344f44a447648489" rel="nofollow" data-download="{"attachment_id":45831194,"asset_id":25509266,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45831194/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="49040718" href="https://independent.academia.edu/JohnEbersole">John Ebersole</a><script data-card-contents-for-user="49040718" type="text/json">{"id":49040718,"first_name":"John","last_name":"Ebersole","domain_name":"independent","page_name":"JohnEbersole","display_name":"John Ebersole","profile_url":"https://independent.academia.edu/JohnEbersole?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_25509266 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="25509266"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 25509266, container: ".js-paper-rank-work_25509266", }); });</script></li><li class="js-percentile-work_25509266 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 25509266; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_25509266"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_25509266 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="25509266"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 25509266; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=25509266]").text(description); $(".js-view-count-work_25509266").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_25509266").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="25509266"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">13</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="2007" rel="nofollow" href="https://www.academia.edu/Documents/in/Electrophysiology">Electrophysiology</a>, <script data-card-contents-for-ri="2007" type="text/json">{"id":2007,"name":"Electrophysiology","url":"https://www.academia.edu/Documents/in/Electrophysiology?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="10904" rel="nofollow" href="https://www.academia.edu/Documents/in/Electroencephalography">Electroencephalography</a>, <script data-card-contents-for-ri="10904" type="text/json">{"id":10904,"name":"Electroencephalography","url":"https://www.academia.edu/Documents/in/Electroencephalography?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="52176" rel="nofollow" href="https://www.academia.edu/Documents/in/Brain_Mapping">Brain Mapping</a><script data-card-contents-for-ri="52176" type="text/json">{"id":52176,"name":"Brain Mapping","url":"https://www.academia.edu/Documents/in/Brain_Mapping?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=25509266]'), work: {"id":25509266,"title":"The Impact of Cerebral Source Area and Synchrony on Recording Scalp Electroencephalography Ictal Patterns","created_at":"2016-05-21T06:12:07.885-07:00","url":"https://www.academia.edu/25509266/The_Impact_of_Cerebral_Source_Area_and_Synchrony_on_Recording_Scalp_Electroencephalography_Ictal_Patterns?f_ri=57557","dom_id":"work_25509266","summary":"Purpose: To determine the cerebral electroencephalography (EEG) substrates of scalp EEG seizure patterns, such as source area and synchrony, and in so doing assess the limitations of scalp seizure recording in the localization of seizure onset zones in patients with temporal lobe epilepsy. Methods: We recorded simultaneously 26 channels of scalp EEG with subtemporal supplementary electrodes and 46-98 channels of intracranial EEG in presurgical candidates with temporal lobe epilepsy. We correlated intracranial EEG source area and synchrony at seizure onset with the corresponding scalp EEG. Eighty-six simultaneous intracranial-and scalp-recorded seizures from 23 patients were evaluated. Results: Thirty-four intracranial ictal discharges (40%) from 9 patients (39%) had sufficient cortical source area (namely \u003e 10 cm 2 ) and synchrony at seizure onset to produce a simultaneous or nearly simultaneous focal scalp EEG ictal pattern.","downloadable_attachments":[{"id":45831194,"asset_id":25509266,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":49040718,"first_name":"John","last_name":"Ebersole","domain_name":"independent","page_name":"JohnEbersole","display_name":"John Ebersole","profile_url":"https://independent.academia.edu/JohnEbersole?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":2007,"name":"Electrophysiology","url":"https://www.academia.edu/Documents/in/Electrophysiology?f_ri=57557","nofollow":true},{"id":10904,"name":"Electroencephalography","url":"https://www.academia.edu/Documents/in/Electroencephalography?f_ri=57557","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=57557","nofollow":true},{"id":52176,"name":"Brain Mapping","url":"https://www.academia.edu/Documents/in/Brain_Mapping?f_ri=57557","nofollow":true},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":78467,"name":"Cerebral Cortex","url":"https://www.academia.edu/Documents/in/Cerebral_Cortex?f_ri=57557"},{"id":128608,"name":"Temporal Lobe Epilepsy","url":"https://www.academia.edu/Documents/in/Temporal_Lobe_Epilepsy?f_ri=57557"},{"id":228487,"name":"Epilepsia","url":"https://www.academia.edu/Documents/in/Epilepsia?f_ri=57557"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=57557"},{"id":846015,"name":"Electrodes","url":"https://www.academia.edu/Documents/in/Electrodes?f_ri=57557"},{"id":909150,"name":"Electrode","url":"https://www.academia.edu/Documents/in/Electrode?f_ri=57557"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=57557"},{"id":2234200,"name":"Functional Laterality","url":"https://www.academia.edu/Documents/in/Functional_Laterality?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_14753925" data-work_id="14753925" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/14753925/Multiplanar_transcranial_ultrasound_imaging_Standards_landmarks_and_correlation_with_magnetic_resonance_imaging">Multiplanar transcranial ultrasound imaging: Standards, landmarks and correlation with magnetic resonance imaging</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The purpose of this study was to define a standardized multiplanar approach for transcranial ultrasound (US) imaging of brain parenchyma based on matched data from 3-D US and 3-D magnetic resonance imaging (MRI). The potential and... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_14753925" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The purpose of this study was to define a standardized multiplanar approach for transcranial ultrasound (US) imaging of brain parenchyma based on matched data from 3-D US and 3-D magnetic resonance imaging (MRI). The potential and limitations of multiple insonation planes in transverse and coronal orientation were evaluated for the visualization of intracranial landmarks in 60 healthy individuals (18 to 83 years old, mean 41.4 years) with sufficient temporal bone windows. Landmarks regularly visualized even in moderate sonographic conditions with identification rates of > 75% were mesencephalon, pons, third ventricle, lateral ventricles, falx, thalamus, basal ganglia, pineal gland and temporal lobe. Identification of medulla oblongata, fourth ventricle, cerebellar structures, hippocampus, insula, frontal, parietal and occipital lobes was more difficult (< 75%). We hypothesize that multiplanar transcranial US images, with standardized specification of tilt angles and orientation, not only allow comparison with other neuroimaging modalities, but may also provide a more objective framework for US monitoring of cerebral disease than freehand scanning. © 2004 World</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/14753925" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a191946c9efdc7b348fceaced27ab23f" rel="nofollow" data-download="{"attachment_id":43915657,"asset_id":14753925,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/43915657/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33719041" href="https://gfri.academia.edu/FabiennePerren">Fabienne Perren</a><script data-card-contents-for-user="33719041" type="text/json">{"id":33719041,"first_name":"Fabienne","last_name":"Perren","domain_name":"gfri","page_name":"FabiennePerren","display_name":"Fabienne Perren","profile_url":"https://gfri.academia.edu/FabiennePerren?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_14753925 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="14753925"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 14753925, container: ".js-paper-rank-work_14753925", }); });</script></li><li class="js-percentile-work_14753925 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14753925; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_14753925"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_14753925 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="14753925"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14753925; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14753925]").text(description); $(".js-view-count-work_14753925").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_14753925").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="14753925"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">11</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="4522" rel="nofollow" href="https://www.academia.edu/Documents/in/Ultrasound_Imaging">Ultrasound Imaging</a>, <script data-card-contents-for-ri="4522" type="text/json">{"id":4522,"name":"Ultrasound Imaging","url":"https://www.academia.edu/Documents/in/Ultrasound_Imaging?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="15639" rel="nofollow" href="https://www.academia.edu/Documents/in/Ultrasound">Ultrasound</a>, <script data-card-contents-for-ri="15639" type="text/json">{"id":15639,"name":"Ultrasound","url":"https://www.academia.edu/Documents/in/Ultrasound?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a><script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=14753925]'), work: {"id":14753925,"title":"Multiplanar transcranial ultrasound imaging: Standards, landmarks and correlation with magnetic resonance imaging","created_at":"2015-08-07T23:25:08.054-07:00","url":"https://www.academia.edu/14753925/Multiplanar_transcranial_ultrasound_imaging_Standards_landmarks_and_correlation_with_magnetic_resonance_imaging?f_ri=57557","dom_id":"work_14753925","summary":"The purpose of this study was to define a standardized multiplanar approach for transcranial ultrasound (US) imaging of brain parenchyma based on matched data from 3-D US and 3-D magnetic resonance imaging (MRI). The potential and limitations of multiple insonation planes in transverse and coronal orientation were evaluated for the visualization of intracranial landmarks in 60 healthy individuals (18 to 83 years old, mean 41.4 years) with sufficient temporal bone windows. Landmarks regularly visualized even in moderate sonographic conditions with identification rates of \u003e 75% were mesencephalon, pons, third ventricle, lateral ventricles, falx, thalamus, basal ganglia, pineal gland and temporal lobe. Identification of medulla oblongata, fourth ventricle, cerebellar structures, hippocampus, insula, frontal, parietal and occipital lobes was more difficult (\u003c 75%). We hypothesize that multiplanar transcranial US images, with standardized specification of tilt angles and orientation, not only allow comparison with other neuroimaging modalities, but may also provide a more objective framework for US monitoring of cerebral disease than freehand scanning. © 2004 World","downloadable_attachments":[{"id":43915657,"asset_id":14753925,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33719041,"first_name":"Fabienne","last_name":"Perren","domain_name":"gfri","page_name":"FabiennePerren","display_name":"Fabienne Perren","profile_url":"https://gfri.academia.edu/FabiennePerren?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":4522,"name":"Ultrasound Imaging","url":"https://www.academia.edu/Documents/in/Ultrasound_Imaging?f_ri=57557","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":15639,"name":"Ultrasound","url":"https://www.academia.edu/Documents/in/Ultrasound?f_ri=57557","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=57557","nofollow":true},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":123287,"name":"Three Dimensional Imaging","url":"https://www.academia.edu/Documents/in/Three_Dimensional_Imaging?f_ri=57557"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=57557"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=57557"},{"id":484219,"name":"Basal ganglia","url":"https://www.academia.edu/Documents/in/Basal_ganglia?f_ri=57557"},{"id":613283,"name":"Pineal Gland","url":"https://www.academia.edu/Documents/in/Pineal_Gland?f_ri=57557"},{"id":815168,"name":"Temporal Bone","url":"https://www.academia.edu/Documents/in/Temporal_Bone?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_15517294 coauthored" data-work_id="15517294" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/15517294/Intracerebral_Cavernous_Hemangioma_after_Cranial_Irradiation_in_Childhood">Intracerebral Cavernous Hemangioma after Cranial Irradiation in Childhood</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Radiotherapy is an integral part of various therapeutic regimens in pediatric and adult oncology. Endocrine dysfunction, neurologic and psychiatric deficits, secondary malignancies and radiation-induced necrosis are well-known possible... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_15517294" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Radiotherapy is an integral part of various therapeutic regimens in pediatric and adult oncology. Endocrine dysfunction, neurologic and psychiatric deficits, secondary malignancies and radiation-induced necrosis are well-known possible late effects of cranial irradiation. However, only sporadic cases of radiation-induced cavernous hemangiomas (RICH) have been reported so far. Patients and Methods: Pediatric patients who underwent cranial radiation therapy for malignant diseases between January 1980 and December 2003 were retrospectively analyzed. After the end of therapy they entered a detailed follow-up program. Results: Of 171 patients, eight (three patients with medulloblastoma, three patients with acute lymphoblastic leukemia, and one patient each with ependymoma and craniopharyngioma) developed intracerebral cavernoma 2.9-18.4 years after irradiation representing a cumulative incidence (according to the Kaplan-Meier method) of 2.24%, 3.86%, 4.95%, and 6.74% within 5, 10, 15, and 20 years following radiation therapy, respectively. In patients treated in the first 10 years of life, RICH occurred with shorter latency and significantly more often (p = 0.044) resulting in an even higher cumulative incidence. Conclusion: These findings and previously published cases show that cavernous hemangiomas may occur after irradiation of the brain several years after the end of therapy irrespective of the radiation dose and type of malignancy. Particularly children < 10 years of age at the time of irradiation are at higher risk. Since patients with RICH frequently do not show symptoms but hemorrhage is a possible severe complication, imaging of the central nervous system should be performed routinely for longer follow-ups, particularly in patients who were treated as young children.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/15517294" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="cbdaeb40971e755979d6ca77585a6530" rel="nofollow" data-download="{"attachment_id":43126706,"asset_id":15517294,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/43126706/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="34669935" rel="nofollow" href="https://independent.academia.edu/VolkerStrenger">Volker Strenger</a><script data-card-contents-for-user="34669935" type="text/json">{"id":34669935,"first_name":"Volker","last_name":"Strenger","domain_name":"independent","page_name":"VolkerStrenger","display_name":"Volker Strenger","profile_url":"https://independent.academia.edu/VolkerStrenger?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-15517294">+1</span><div class="hidden js-additional-users-15517294"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/HerwigLackner">Herwig Lackner</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-15517294'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-15517294').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_15517294 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="15517294"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 15517294, container: ".js-paper-rank-work_15517294", }); });</script></li><li class="js-percentile-work_15517294 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 15517294; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_15517294"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_15517294 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="15517294"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 15517294; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=15517294]").text(description); $(".js-view-count-work_15517294").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_15517294").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="15517294"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">21</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="10030" rel="nofollow" href="https://www.academia.edu/Documents/in/Radiation_Therapy">Radiation Therapy</a>, <script data-card-contents-for-ri="10030" type="text/json">{"id":10030,"name":"Radiation Therapy","url":"https://www.academia.edu/Documents/in/Radiation_Therapy?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="57557" rel="nofollow" href="https://www.academia.edu/Documents/in/Temporal_Lobe">Temporal Lobe</a><script data-card-contents-for-ri="57557" type="text/json">{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=15517294]'), work: {"id":15517294,"title":"Intracerebral Cavernous Hemangioma after Cranial Irradiation in Childhood","created_at":"2015-09-08T12:09:13.747-07:00","url":"https://www.academia.edu/15517294/Intracerebral_Cavernous_Hemangioma_after_Cranial_Irradiation_in_Childhood?f_ri=57557","dom_id":"work_15517294","summary":"Radiotherapy is an integral part of various therapeutic regimens in pediatric and adult oncology. Endocrine dysfunction, neurologic and psychiatric deficits, secondary malignancies and radiation-induced necrosis are well-known possible late effects of cranial irradiation. However, only sporadic cases of radiation-induced cavernous hemangiomas (RICH) have been reported so far. Patients and Methods: Pediatric patients who underwent cranial radiation therapy for malignant diseases between January 1980 and December 2003 were retrospectively analyzed. After the end of therapy they entered a detailed follow-up program. Results: Of 171 patients, eight (three patients with medulloblastoma, three patients with acute lymphoblastic leukemia, and one patient each with ependymoma and craniopharyngioma) developed intracerebral cavernoma 2.9-18.4 years after irradiation representing a cumulative incidence (according to the Kaplan-Meier method) of 2.24%, 3.86%, 4.95%, and 6.74% within 5, 10, 15, and 20 years following radiation therapy, respectively. In patients treated in the first 10 years of life, RICH occurred with shorter latency and significantly more often (p = 0.044) resulting in an even higher cumulative incidence. Conclusion: These findings and previously published cases show that cavernous hemangiomas may occur after irradiation of the brain several years after the end of therapy irrespective of the radiation dose and type of malignancy. Particularly children \u003c 10 years of age at the time of irradiation are at higher risk. Since patients with RICH frequently do not show symptoms but hemorrhage is a possible severe complication, imaging of the central nervous system should be performed routinely for longer follow-ups, particularly in patients who were treated as young children.","downloadable_attachments":[{"id":43126706,"asset_id":15517294,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":34669935,"first_name":"Volker","last_name":"Strenger","domain_name":"independent","page_name":"VolkerStrenger","display_name":"Volker Strenger","profile_url":"https://independent.academia.edu/VolkerStrenger?f_ri=57557","photo":"/images/s65_no_pic.png"},{"id":55430948,"first_name":"Herwig","last_name":"Lackner","domain_name":"independent","page_name":"HerwigLackner","display_name":"Herwig Lackner","profile_url":"https://independent.academia.edu/HerwigLackner?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":10030,"name":"Radiation Therapy","url":"https://www.academia.edu/Documents/in/Radiation_Therapy?f_ri=57557","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=57557","nofollow":true},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557","nofollow":true},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=57557"},{"id":74725,"name":"Medulloblastoma","url":"https://www.academia.edu/Documents/in/Medulloblastoma?f_ri=57557"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=57557"},{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies?f_ri=57557"},{"id":147195,"name":"Central Nervous System","url":"https://www.academia.edu/Documents/in/Central_Nervous_System?f_ri=57557"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=57557"},{"id":372494,"name":"Kaplan-Meier","url":"https://www.academia.edu/Documents/in/Kaplan-Meier?f_ri=57557"},{"id":389506,"name":"Radiation Dose","url":"https://www.academia.edu/Documents/in/Radiation_Dose?f_ri=57557"},{"id":406036,"name":"Parietal Lobe","url":"https://www.academia.edu/Documents/in/Parietal_Lobe?f_ri=57557"},{"id":538047,"name":"Young Children","url":"https://www.academia.edu/Documents/in/Young_Children?f_ri=57557"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=57557"},{"id":959921,"name":"X ray Computed Tomography","url":"https://www.academia.edu/Documents/in/X_ray_Computed_Tomography?f_ri=57557"},{"id":1257483,"name":"Frontal Lobe","url":"https://www.academia.edu/Documents/in/Frontal_Lobe?f_ri=57557"},{"id":1425045,"name":"Brain Neoplasms","url":"https://www.academia.edu/Documents/in/Brain_Neoplasms?f_ri=57557"},{"id":1630613,"name":"Acute Lymphoblastic Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Lymphoblastic_Leukemia?f_ri=57557"},{"id":1733657,"name":"Cumulative Incidence","url":"https://www.academia.edu/Documents/in/Cumulative_Incidence?f_ri=57557"},{"id":2112659,"name":"Craniopharyngioma","url":"https://www.academia.edu/Documents/in/Craniopharyngioma?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_21222393" data-work_id="21222393" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/21222393/Sex_differences_in_handedness_asymmetry_of_the_Planum_Temporale_and_functional_language_lateralization">Sex differences in handedness, asymmetry of the Planum Temporale and functional language lateralization</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Many studies have investigated sex differences in language lateralization. Despite the large number of investigations, controversy about the presence of sex differences in lateralization remains. This study aims to provide a complete... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_21222393" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Many studies have investigated sex differences in language lateralization. Despite the large number of investigations, controversy about the presence of sex differences in lateralization remains. This study aims to provide a complete overview of sex differences in several reflections of language lateralization: handedness, asymmetry of the Planum Temporale (PT) and functional lateralization of language, measured by asymmetric performance on dichotic listening tests (Right Ear Advantage) and asymmetry of language activation as measured with functional imaging techniques. Meta-analysis of studies that assessed handedness in males and females yielded more left-handedness in males (mean weighted odds ratio: 1.25, p b 0.001).</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/21222393" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="1fdae827300223623247638ae7124a55" rel="nofollow" data-download="{"attachment_id":41769538,"asset_id":21222393,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/41769538/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="27927856" href="https://uu.academia.edu/MarcoBoks">Marco P M Boks</a><script data-card-contents-for-user="27927856" type="text/json">{"id":27927856,"first_name":"Marco","last_name":"Boks","domain_name":"uu","page_name":"MarcoBoks","display_name":"Marco P M Boks","profile_url":"https://uu.academia.edu/MarcoBoks?f_ri=57557","photo":"https://0.academia-photos.com/27927856/8437520/33372923/s65_marco.boks.jpg"}</script></span></span></li><li class="js-paper-rank-work_21222393 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="21222393"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 21222393, container: ".js-paper-rank-work_21222393", }); 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$(".js-view-count[data-work-id=21222393]").text(description); $(".js-view-count-work_21222393").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_21222393").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="21222393"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">19</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="237" rel="nofollow" href="https://www.academia.edu/Documents/in/Cognitive_Science">Cognitive Science</a>, <script data-card-contents-for-ri="237" type="text/json">{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="18174" rel="nofollow" href="https://www.academia.edu/Documents/in/Language">Language</a>, <script data-card-contents-for-ri="18174" type="text/json">{"id":18174,"name":"Language","url":"https://www.academia.edu/Documents/in/Language?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="42799" rel="nofollow" href="https://www.academia.edu/Documents/in/Speech">Speech</a><script data-card-contents-for-ri="42799" type="text/json">{"id":42799,"name":"Speech","url":"https://www.academia.edu/Documents/in/Speech?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=21222393]'), work: {"id":21222393,"title":"Sex differences in handedness, asymmetry of the Planum Temporale and functional language lateralization","created_at":"2016-01-30T03:03:54.337-08:00","url":"https://www.academia.edu/21222393/Sex_differences_in_handedness_asymmetry_of_the_Planum_Temporale_and_functional_language_lateralization?f_ri=57557","dom_id":"work_21222393","summary":"Many studies have investigated sex differences in language lateralization. Despite the large number of investigations, controversy about the presence of sex differences in lateralization remains. This study aims to provide a complete overview of sex differences in several reflections of language lateralization: handedness, asymmetry of the Planum Temporale (PT) and functional lateralization of language, measured by asymmetric performance on dichotic listening tests (Right Ear Advantage) and asymmetry of language activation as measured with functional imaging techniques. Meta-analysis of studies that assessed handedness in males and females yielded more left-handedness in males (mean weighted odds ratio: 1.25, p b 0.001).","downloadable_attachments":[{"id":41769538,"asset_id":21222393,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":27927856,"first_name":"Marco","last_name":"Boks","domain_name":"uu","page_name":"MarcoBoks","display_name":"Marco P M Boks","profile_url":"https://uu.academia.edu/MarcoBoks?f_ri=57557","photo":"https://0.academia-photos.com/27927856/8437520/33372923/s65_marco.boks.jpg"}],"research_interests":[{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true},{"id":18174,"name":"Language","url":"https://www.academia.edu/Documents/in/Language?f_ri=57557","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=57557","nofollow":true},{"id":42799,"name":"Speech","url":"https://www.academia.edu/Documents/in/Speech?f_ri=57557","nofollow":true},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain?f_ri=57557"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=57557"},{"id":75509,"name":"Sex Difference","url":"https://www.academia.edu/Documents/in/Sex_Difference?f_ri=57557"},{"id":100946,"name":"Functional Imaging","url":"https://www.academia.edu/Documents/in/Functional_Imaging?f_ri=57557"},{"id":197354,"name":"Dichotic Listening","url":"https://www.academia.edu/Documents/in/Dichotic_Listening?f_ri=57557"},{"id":218206,"name":"Meta Analysis","url":"https://www.academia.edu/Documents/in/Meta_Analysis?f_ri=57557"},{"id":226288,"name":"Publication Bias","url":"https://www.academia.edu/Documents/in/Publication_Bias?f_ri=57557"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=57557"},{"id":437772,"name":"Odds ratio","url":"https://www.academia.edu/Documents/in/Odds_ratio?f_ri=57557"},{"id":975049,"name":"Right Ear Advantage","url":"https://www.academia.edu/Documents/in/Right_Ear_Advantage?f_ri=57557"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=57557"},{"id":1274453,"name":"Right Handed","url":"https://www.academia.edu/Documents/in/Right_Handed?f_ri=57557"},{"id":1772107,"name":"Functional Language","url":"https://www.academia.edu/Documents/in/Functional_Language?f_ri=57557"},{"id":2234200,"name":"Functional Laterality","url":"https://www.academia.edu/Documents/in/Functional_Laterality?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_18218612" data-work_id="18218612" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/18218612/Discrete_Cortical_Regions_Associated_with_Knowledge_of_Color_and_Knowledge_of_Action">Discrete Cortical Regions Associated with Knowledge of Color and Knowledge of Action</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/18218612" data-share-source="work_strip" 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itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="38208072" href="https://independent.academia.edu/LeslieUngerleider">Leslie Ungerleider</a><script data-card-contents-for-user="38208072" type="text/json">{"id":38208072,"first_name":"Leslie","last_name":"Ungerleider","domain_name":"independent","page_name":"LeslieUngerleider","display_name":"Leslie Ungerleider","profile_url":"https://independent.academia.edu/LeslieUngerleider?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_18218612 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="18218612"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 18218612, container: ".js-paper-rank-work_18218612", }); });</script></li><li class="js-percentile-work_18218612 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 18218612; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_18218612"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_18218612 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="18218612"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 18218612; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=18218612]").text(description); $(".js-view-count-work_18218612").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_18218612").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="18218612"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="4212" rel="nofollow" href="https://www.academia.edu/Documents/in/Cognition">Cognition</a>, <script data-card-contents-for-ri="4212" type="text/json">{"id":4212,"name":"Cognition","url":"https://www.academia.edu/Documents/in/Cognition?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6779" rel="nofollow" href="https://www.academia.edu/Documents/in/Science">Science</a>, <script data-card-contents-for-ri="6779" type="text/json">{"id":6779,"name":"Science","url":"https://www.academia.edu/Documents/in/Science?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="13493" rel="nofollow" href="https://www.academia.edu/Documents/in/Motion_perception">Motion perception</a>, <script data-card-contents-for-ri="13493" type="text/json">{"id":13493,"name":"Motion perception","url":"https://www.academia.edu/Documents/in/Motion_perception?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="28235" rel="nofollow" href="https://www.academia.edu/Documents/in/Multidisciplinary">Multidisciplinary</a><script data-card-contents-for-ri="28235" type="text/json">{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=18218612]'), work: {"id":18218612,"title":"Discrete Cortical Regions Associated with Knowledge of Color and Knowledge of Action","created_at":"2015-11-12T11:25:02.694-08:00","url":"https://www.academia.edu/18218612/Discrete_Cortical_Regions_Associated_with_Knowledge_of_Color_and_Knowledge_of_Action?f_ri=57557","dom_id":"work_18218612","summary":null,"downloadable_attachments":[{"id":42113397,"asset_id":18218612,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":38208072,"first_name":"Leslie","last_name":"Ungerleider","domain_name":"independent","page_name":"LeslieUngerleider","display_name":"Leslie Ungerleider","profile_url":"https://independent.academia.edu/LeslieUngerleider?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":4212,"name":"Cognition","url":"https://www.academia.edu/Documents/in/Cognition?f_ri=57557","nofollow":true},{"id":6779,"name":"Science","url":"https://www.academia.edu/Documents/in/Science?f_ri=57557","nofollow":true},{"id":13493,"name":"Motion perception","url":"https://www.academia.edu/Documents/in/Motion_perception?f_ri=57557","nofollow":true},{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary?f_ri=57557","nofollow":true},{"id":38756,"name":"Color Perception","url":"https://www.academia.edu/Documents/in/Color_Perception?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":78467,"name":"Cerebral Cortex","url":"https://www.academia.edu/Documents/in/Cerebral_Cortex?f_ri=57557"},{"id":375439,"name":"Single Photon Emission Computed Tomography","url":"https://www.academia.edu/Documents/in/Single_Photon_Emission_Computed_Tomography?f_ri=57557"},{"id":1257483,"name":"Frontal Lobe","url":"https://www.academia.edu/Documents/in/Frontal_Lobe?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_77438163 coauthored" data-work_id="77438163" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/77438163/The_Human_Parahippocampal_Region_I_Temporal_Pole_Cytoarchitectonic_and_MRI_Correlation">The Human Parahippocampal Region: I. Temporal Pole Cytoarchitectonic and MRI Correlation</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The temporal pole (TP) is the rostralmost portion of the human temporal lobe. Characteristically, it is only present in human and nonhuman primates. TP has been implicated in different cognitive functions such as emotion, attention,... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_77438163" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The temporal pole (TP) is the rostralmost portion of the human temporal lobe. Characteristically, it is only present in human and nonhuman primates. TP has been implicated in different cognitive functions such as emotion, attention, behavior, and memory, based on functional studies performed in healthy controls and patients with neurodegenerative diseases through its anatomical connections (amygdala, pulvinar, orbitofrontal cortex). TP was originally described as a single uniform area by Brodmann area 38, and von Economo (area TG of von Economo and Koskinas), and little information on its cytoarchitectonics is known in humans. We hypothesize that 1) TP is not a homogenous area and we aim first at fixating the precise extent and limits of temporopolar cortex (TPC) with adjacent fields and 2) its structure can be correlated with structural magnetic resonance images. We describe here the macroscopic characteristics and cytoarchitecture as two subfields, a medial and a lateral area, that constitute TPC also noticeable in 2D and 3D reconstructions. Our findings suggest that the human TP is a heterogeneous region formed exclusively by TPC for about 7 mm of the temporal tip, and that becomes progressively restricted to the medial and ventral sides of the TP. This cortical area presents topographical and structural features in common with nonhuman primates, which suggests an evolutionary development in human species.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/77438163" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="2bd5a5b7bedde6f4ddc1791631120bda" rel="nofollow" data-download="{"attachment_id":84902650,"asset_id":77438163,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/84902650/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="46417848" href="https://independent.academia.edu/PalmaProSistiaga">Palma Pro-Sistiaga</a><script data-card-contents-for-user="46417848" type="text/json">{"id":46417848,"first_name":"Palma","last_name":"Pro-Sistiaga","domain_name":"independent","page_name":"PalmaProSistiaga","display_name":"Palma Pro-Sistiaga","profile_url":"https://independent.academia.edu/PalmaProSistiaga?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-77438163">+1</span><div class="hidden js-additional-users-77438163"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://unavarra.academia.edu/AnaInsausti">Ana Insausti</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-77438163'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-77438163').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_77438163 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="77438163"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 77438163, container: ".js-paper-rank-work_77438163", }); });</script></li><li class="js-percentile-work_77438163 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 77438163; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_77438163"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_77438163 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="77438163"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 77438163; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=77438163]").text(description); $(".js-view-count-work_77438163").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_77438163").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="77438163"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">15</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="237" rel="nofollow" href="https://www.academia.edu/Documents/in/Cognitive_Science">Cognitive Science</a>, <script data-card-contents-for-ri="237" type="text/json">{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a><script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=77438163]'), work: {"id":77438163,"title":"The Human Parahippocampal Region: I. Temporal Pole Cytoarchitectonic and MRI Correlation","created_at":"2022-04-24T03:48:26.278-07:00","url":"https://www.academia.edu/77438163/The_Human_Parahippocampal_Region_I_Temporal_Pole_Cytoarchitectonic_and_MRI_Correlation?f_ri=57557","dom_id":"work_77438163","summary":"The temporal pole (TP) is the rostralmost portion of the human temporal lobe. Characteristically, it is only present in human and nonhuman primates. TP has been implicated in different cognitive functions such as emotion, attention, behavior, and memory, based on functional studies performed in healthy controls and patients with neurodegenerative diseases through its anatomical connections (amygdala, pulvinar, orbitofrontal cortex). TP was originally described as a single uniform area by Brodmann area 38, and von Economo (area TG of von Economo and Koskinas), and little information on its cytoarchitectonics is known in humans. We hypothesize that 1) TP is not a homogenous area and we aim first at fixating the precise extent and limits of temporopolar cortex (TPC) with adjacent fields and 2) its structure can be correlated with structural magnetic resonance images. We describe here the macroscopic characteristics and cytoarchitecture as two subfields, a medial and a lateral area, that constitute TPC also noticeable in 2D and 3D reconstructions. Our findings suggest that the human TP is a heterogeneous region formed exclusively by TPC for about 7 mm of the temporal tip, and that becomes progressively restricted to the medial and ventral sides of the TP. This cortical area presents topographical and structural features in common with nonhuman primates, which suggests an evolutionary development in human species.","downloadable_attachments":[{"id":84902650,"asset_id":77438163,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":46417848,"first_name":"Palma","last_name":"Pro-Sistiaga","domain_name":"independent","page_name":"PalmaProSistiaga","display_name":"Palma Pro-Sistiaga","profile_url":"https://independent.academia.edu/PalmaProSistiaga?f_ri=57557","photo":"/images/s65_no_pic.png"},{"id":46499775,"first_name":"Ana","last_name":"Insausti","domain_name":"unavarra","page_name":"AnaInsausti","display_name":"Ana Insausti","profile_url":"https://unavarra.academia.edu/AnaInsausti?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true},{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=57557","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=57557"},{"id":52176,"name":"Brain Mapping","url":"https://www.academia.edu/Documents/in/Brain_Mapping?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=57557"},{"id":78467,"name":"Cerebral Cortex","url":"https://www.academia.edu/Documents/in/Cerebral_Cortex?f_ri=57557"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=57557"},{"id":193974,"name":"Neurons","url":"https://www.academia.edu/Documents/in/Neurons?f_ri=57557"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=57557"},{"id":346333,"name":"Cerebral","url":"https://www.academia.edu/Documents/in/Cerebral?f_ri=57557"},{"id":865670,"name":"Parahippocampal Gyrus","url":"https://www.academia.edu/Documents/in/Parahippocampal_Gyrus?f_ri=57557"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_71608569" data-work_id="71608569" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/71608569/A_Case_Study_of_Selective_Impairment_of_the_Central_Executive_Component_of_Working_Memory_after_a_Focal_Frontal_Lobe_Damage">A Case Study of Selective Impairment of the Central Executive Component of Working Memory after a Focal Frontal Lobe Damage</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">RC is a 36-year-old man who sustained a closed head injury with bilateral frontal lobe hypometabolism in 1978. In 1994, after a lobectomy of a large part of the left frontal lobe, he presented no behavioral disruption and normal... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_71608569" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">RC is a 36-year-old man who sustained a closed head injury with bilateral frontal lobe hypometabolism in 1978. In 1994, after a lobectomy of a large part of the left frontal lobe, he presented no behavioral disruption and normal performances on most of intelligence, longterm memory, and executive tests. However, he showed deficits in tasks that implicate shortterm storage (i.e., span tasks). These deficits in working memory were explored with regard to Baddeley's model using computerized tasks. On these tasks RC showed normal functioning of the articulatory loops and dysfunction of the central executive component in dual tasks. These results confirm those reported in another single case study by Van Der Linden, Coyette, and Seron (1992) and indicate that dual-task performance may assess one separable feature of executive functions.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/71608569" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="5b66d6a7c4115351562ec8cc21c56faf" rel="nofollow" data-download="{"attachment_id":80879281,"asset_id":71608569,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/80879281/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32069804" href="https://independent.academia.edu/AllainPhilippe">Philippe Allain</a><script data-card-contents-for-user="32069804" type="text/json">{"id":32069804,"first_name":"Philippe","last_name":"Allain","domain_name":"independent","page_name":"AllainPhilippe","display_name":"Philippe Allain","profile_url":"https://independent.academia.edu/AllainPhilippe?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_71608569 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="71608569"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 71608569, container: ".js-paper-rank-work_71608569", }); });</script></li><li class="js-percentile-work_71608569 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 71608569; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_71608569"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_71608569 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="71608569"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 71608569; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=71608569]").text(description); $(".js-view-count-work_71608569").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_71608569").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="71608569"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">17</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="237" rel="nofollow" href="https://www.academia.edu/Documents/in/Cognitive_Science">Cognitive Science</a>, <script data-card-contents-for-ri="237" type="text/json">{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="8538" rel="nofollow" href="https://www.academia.edu/Documents/in/Working_Memory">Working Memory</a>, <script data-card-contents-for-ri="8538" type="text/json">{"id":8538,"name":"Working Memory","url":"https://www.academia.edu/Documents/in/Working_Memory?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a><script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=71608569]'), work: {"id":71608569,"title":"A Case Study of Selective Impairment of the Central Executive Component of Working Memory after a Focal Frontal Lobe Damage","created_at":"2022-02-15T06:10:26.175-08:00","url":"https://www.academia.edu/71608569/A_Case_Study_of_Selective_Impairment_of_the_Central_Executive_Component_of_Working_Memory_after_a_Focal_Frontal_Lobe_Damage?f_ri=57557","dom_id":"work_71608569","summary":"RC is a 36-year-old man who sustained a closed head injury with bilateral frontal lobe hypometabolism in 1978. In 1994, after a lobectomy of a large part of the left frontal lobe, he presented no behavioral disruption and normal performances on most of intelligence, longterm memory, and executive tests. However, he showed deficits in tasks that implicate shortterm storage (i.e., span tasks). These deficits in working memory were explored with regard to Baddeley's model using computerized tasks. On these tasks RC showed normal functioning of the articulatory loops and dysfunction of the central executive component in dual tasks. These results confirm those reported in another single case study by Van Der Linden, Coyette, and Seron (1992) and indicate that dual-task performance may assess one separable feature of executive functions.","downloadable_attachments":[{"id":80879281,"asset_id":71608569,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32069804,"first_name":"Philippe","last_name":"Allain","domain_name":"independent","page_name":"AllainPhilippe","display_name":"Philippe Allain","profile_url":"https://independent.academia.edu/AllainPhilippe?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true},{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true},{"id":8538,"name":"Working Memory","url":"https://www.academia.edu/Documents/in/Working_Memory?f_ri=57557","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=57557","nofollow":true},{"id":33732,"name":"Executive Function","url":"https://www.academia.edu/Documents/in/Executive_Function?f_ri=57557"},{"id":41819,"name":"Brain and Cognition","url":"https://www.academia.edu/Documents/in/Brain_and_Cognition?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":96047,"name":"Case Study","url":"https://www.academia.edu/Documents/in/Case_Study?f_ri=57557"},{"id":232257,"name":"Dual Task","url":"https://www.academia.edu/Documents/in/Dual_Task?f_ri=57557"},{"id":522465,"name":"Long Term Memory","url":"https://www.academia.edu/Documents/in/Long_Term_Memory?f_ri=57557"},{"id":565305,"name":"Brain Abscess","url":"https://www.academia.edu/Documents/in/Brain_Abscess?f_ri=57557"},{"id":959921,"name":"X ray Computed Tomography","url":"https://www.academia.edu/Documents/in/X_ray_Computed_Tomography?f_ri=57557"},{"id":974411,"name":"Memory Disorders","url":"https://www.academia.edu/Documents/in/Memory_Disorders?f_ri=57557"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=57557"},{"id":1257483,"name":"Frontal Lobe","url":"https://www.academia.edu/Documents/in/Frontal_Lobe?f_ri=57557"},{"id":2467548,"name":"Neuropsychological Tests","url":"https://www.academia.edu/Documents/in/Neuropsychological_Tests?f_ri=57557"},{"id":2474622,"name":"Recovery of Function","url":"https://www.academia.edu/Documents/in/Recovery_of_Function?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_70824609" data-work_id="70824609" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/70824609/The_role_of_the_right_temporoparietal_junction_in_the_control_of_imitation">The role of the right temporoparietal junction in the control of imitation</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Controlling neural representations of the self and other people is fun-damental to social cognition. Brain imaging studies have implicated the right temporoparietal junction (rTPJ) in this ability, but causal evidence for its role is... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_70824609" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Controlling neural representations of the self and other people is fun-damental to social cognition. Brain imaging studies have implicated the right temporoparietal junction (rTPJ) in this ability, but causal evidence for its role is lacking. A debate is also ongoing regarding whether the control of, or switching between, self and other rep-resentations is a specialized or domain-general process: the rTPJ’s well-established role in reorienting attention supports a domain-general process, but a role specific to social cognition has also been proposed. Neuronavigated repetitive transcranial magnetic stimu-lation was used to target the rTPJ (and a control mid-occipital site) during a task requiring participants to switch between represen-tations of others ’ actions on both a social and a nonsocial level, by manipulating imitative and spatial compatibility simultaneously and independently. Both imitative and spatial compatibility effects were apparent on response times; however, the eff...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/70824609" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="b36c7ae53d281c7b8ae3bc7229cde3a3" rel="nofollow" data-download="{"attachment_id":80410495,"asset_id":70824609,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/80410495/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="41675405" href="https://bham.academia.edu/SSowden">Sophie Sowden</a><script data-card-contents-for-user="41675405" type="text/json">{"id":41675405,"first_name":"Sophie","last_name":"Sowden","domain_name":"bham","page_name":"SSowden","display_name":"Sophie Sowden","profile_url":"https://bham.academia.edu/SSowden?f_ri=57557","photo":"https://0.academia-photos.com/41675405/11529031/61295139/s65_sophie.sowden.jpg"}</script></span></span></li><li class="js-paper-rank-work_70824609 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="70824609"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 70824609, container: ".js-paper-rank-work_70824609", }); 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$(".js-view-count[data-work-id=70824609]").text(description); $(".js-view-count-work_70824609").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_70824609").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="70824609"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">15</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="237" rel="nofollow" href="https://www.academia.edu/Documents/in/Cognitive_Science">Cognitive Science</a>, <script data-card-contents-for-ri="237" type="text/json">{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4626" rel="nofollow" href="https://www.academia.edu/Documents/in/Social_Cognition">Social Cognition</a>, <script data-card-contents-for-ri="4626" type="text/json">{"id":4626,"name":"Social Cognition","url":"https://www.academia.edu/Documents/in/Social_Cognition?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a><script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=70824609]'), work: {"id":70824609,"title":"The role of the right temporoparietal junction in the control of imitation","created_at":"2022-02-07T01:57:26.940-08:00","url":"https://www.academia.edu/70824609/The_role_of_the_right_temporoparietal_junction_in_the_control_of_imitation?f_ri=57557","dom_id":"work_70824609","summary":"Controlling neural representations of the self and other people is fun-damental to social cognition. Brain imaging studies have implicated the right temporoparietal junction (rTPJ) in this ability, but causal evidence for its role is lacking. A debate is also ongoing regarding whether the control of, or switching between, self and other rep-resentations is a specialized or domain-general process: the rTPJ’s well-established role in reorienting attention supports a domain-general process, but a role specific to social cognition has also been proposed. Neuronavigated repetitive transcranial magnetic stimu-lation was used to target the rTPJ (and a control mid-occipital site) during a task requiring participants to switch between represen-tations of others ’ actions on both a social and a nonsocial level, by manipulating imitative and spatial compatibility simultaneously and independently. Both imitative and spatial compatibility effects were apparent on response times; however, the eff...","downloadable_attachments":[{"id":80410495,"asset_id":70824609,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":41675405,"first_name":"Sophie","last_name":"Sowden","domain_name":"bham","page_name":"SSowden","display_name":"Sophie Sowden","profile_url":"https://bham.academia.edu/SSowden?f_ri=57557","photo":"https://0.academia-photos.com/41675405/11529031/61295139/s65_sophie.sowden.jpg"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true},{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true},{"id":4626,"name":"Social Cognition","url":"https://www.academia.edu/Documents/in/Social_Cognition?f_ri=57557","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=57557","nofollow":true},{"id":42361,"name":"TMS","url":"https://www.academia.edu/Documents/in/TMS?f_ri=57557"},{"id":53331,"name":"Social behavior","url":"https://www.academia.edu/Documents/in/Social_behavior?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":78467,"name":"Cerebral Cortex","url":"https://www.academia.edu/Documents/in/Cerebral_Cortex?f_ri=57557"},{"id":100936,"name":"Imitation","url":"https://www.academia.edu/Documents/in/Imitation?f_ri=57557"},{"id":119665,"name":"Reaction Time","url":"https://www.academia.edu/Documents/in/Reaction_Time?f_ri=57557"},{"id":406036,"name":"Parietal Lobe","url":"https://www.academia.edu/Documents/in/Parietal_Lobe?f_ri=57557"},{"id":628583,"name":"Social Behavior","url":"https://www.academia.edu/Documents/in/Social_Behavior-1?f_ri=57557"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=57557"},{"id":2234200,"name":"Functional Laterality","url":"https://www.academia.edu/Documents/in/Functional_Laterality?f_ri=57557"},{"id":2467548,"name":"Neuropsychological Tests","url":"https://www.academia.edu/Documents/in/Neuropsychological_Tests?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_33157488" data-work_id="33157488" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/33157488/Interpersonal_traits_of_psychopathy_linked_to_reduced_integrity_of_the_uncinate_fasciculus">Interpersonal traits of psychopathy linked to reduced integrity of the uncinate fasciculus</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Psychopathy is a personality disorder characterized by callous lack of empathy, impulsive antisocial behavior, and criminal recidivism. Here, we performed the largest diffusion tensor imaging (DTI) study of incarcerated criminal offenders... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_33157488" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Psychopathy is a personality disorder characterized by callous lack of empathy, impulsive antisocial behavior, and criminal recidivism. Here, we performed the largest diffusion tensor imaging (DTI) study of incarcerated criminal offenders to date (N 5 147) to determine whether psychopathy severity is linked to the microstructural integrity of major white matter tracts in the brain. Consistent with the results of previous studies in smaller samples, we found that psychopathy was associated with reduced fractional anisotropy in the right uncinate fasciculus (UF; the major white matter tract connecting ventral frontal and anterior temporal cortices). We found no such association in the left UF or in adjacent frontal or temporal white matter tracts. Moreover, the right UF finding was specifically related to the interpersonal features of psychopathy (glib superficial charm, grandiose sense of self-worth, pathological lying, manipulativeness), rather than the affective, antisocial, or lifestyle features. These results indicate a neural marker for this key dimension of psychopathic symptomatology. Hum Brain Mapp 00:000-000, 2015.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/33157488" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="588f60271bb97d4b669e83e7a872ffb9" rel="nofollow" data-download="{"attachment_id":53245268,"asset_id":33157488,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/53245268/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="9322" href="https://chicago.academia.edu/JeanDecety">Jean Decety</a><script data-card-contents-for-user="9322" type="text/json">{"id":9322,"first_name":"Jean","last_name":"Decety","domain_name":"chicago","page_name":"JeanDecety","display_name":"Jean Decety","profile_url":"https://chicago.academia.edu/JeanDecety?f_ri=57557","photo":"https://0.academia-photos.com/9322/3226/12396117/s65_jean.decety.jpg"}</script></span></span></li><li class="js-paper-rank-work_33157488 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="33157488"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 33157488, container: ".js-paper-rank-work_33157488", }); });</script></li><li class="js-percentile-work_33157488 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33157488; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_33157488"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_33157488 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="33157488"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33157488; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33157488]").text(description); $(".js-view-count-work_33157488").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_33157488").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="33157488"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">17</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="237" rel="nofollow" href="https://www.academia.edu/Documents/in/Cognitive_Science">Cognitive Science</a>, <script data-card-contents-for-ri="237" type="text/json">{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="8929" rel="nofollow" href="https://www.academia.edu/Documents/in/Diffusion_Tensor_Imaging">Diffusion Tensor Imaging</a>, <script data-card-contents-for-ri="8929" type="text/json">{"id":8929,"name":"Diffusion Tensor Imaging","url":"https://www.academia.edu/Documents/in/Diffusion_Tensor_Imaging?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="37333" rel="nofollow" href="https://www.academia.edu/Documents/in/Anisotropy">Anisotropy</a><script data-card-contents-for-ri="37333" type="text/json">{"id":37333,"name":"Anisotropy","url":"https://www.academia.edu/Documents/in/Anisotropy?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=33157488]'), work: {"id":33157488,"title":"Interpersonal traits of psychopathy linked to reduced integrity of the uncinate fasciculus","created_at":"2017-05-23T04:39:01.357-07:00","url":"https://www.academia.edu/33157488/Interpersonal_traits_of_psychopathy_linked_to_reduced_integrity_of_the_uncinate_fasciculus?f_ri=57557","dom_id":"work_33157488","summary":"Psychopathy is a personality disorder characterized by callous lack of empathy, impulsive antisocial behavior, and criminal recidivism. Here, we performed the largest diffusion tensor imaging (DTI) study of incarcerated criminal offenders to date (N 5 147) to determine whether psychopathy severity is linked to the microstructural integrity of major white matter tracts in the brain. Consistent with the results of previous studies in smaller samples, we found that psychopathy was associated with reduced fractional anisotropy in the right uncinate fasciculus (UF; the major white matter tract connecting ventral frontal and anterior temporal cortices). We found no such association in the left UF or in adjacent frontal or temporal white matter tracts. Moreover, the right UF finding was specifically related to the interpersonal features of psychopathy (glib superficial charm, grandiose sense of self-worth, pathological lying, manipulativeness), rather than the affective, antisocial, or lifestyle features. These results indicate a neural marker for this key dimension of psychopathic symptomatology. Hum Brain Mapp 00:000-000, 2015.","downloadable_attachments":[{"id":53245268,"asset_id":33157488,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":9322,"first_name":"Jean","last_name":"Decety","domain_name":"chicago","page_name":"JeanDecety","display_name":"Jean Decety","profile_url":"https://chicago.academia.edu/JeanDecety?f_ri=57557","photo":"https://0.academia-photos.com/9322/3226/12396117/s65_jean.decety.jpg"}],"research_interests":[{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=57557","nofollow":true},{"id":8929,"name":"Diffusion Tensor Imaging","url":"https://www.academia.edu/Documents/in/Diffusion_Tensor_Imaging?f_ri=57557","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=57557","nofollow":true},{"id":37333,"name":"Anisotropy","url":"https://www.academia.edu/Documents/in/Anisotropy?f_ri=57557","nofollow":true},{"id":44273,"name":"Antisocial Personality Disorder","url":"https://www.academia.edu/Documents/in/Antisocial_Personality_Disorder?f_ri=57557"},{"id":52176,"name":"Brain Mapping","url":"https://www.academia.edu/Documents/in/Brain_Mapping?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=57557"},{"id":172809,"name":"Interpersonal Relations","url":"https://www.academia.edu/Documents/in/Interpersonal_Relations?f_ri=57557"},{"id":362036,"name":"White matter","url":"https://www.academia.edu/Documents/in/White_matter?f_ri=57557"},{"id":685368,"name":"Human Brain Mapping","url":"https://www.academia.edu/Documents/in/Human_Brain_Mapping?f_ri=57557"},{"id":1115225,"name":"Personality Tests","url":"https://www.academia.edu/Documents/in/Personality_Tests?f_ri=57557"},{"id":1132792,"name":"Criminals","url":"https://www.academia.edu/Documents/in/Criminals?f_ri=57557"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=57557"},{"id":1257483,"name":"Frontal Lobe","url":"https://www.academia.edu/Documents/in/Frontal_Lobe?f_ri=57557"},{"id":1423077,"name":"Substance-Related Disorders","url":"https://www.academia.edu/Documents/in/Substance-Related_Disorders?f_ri=57557"},{"id":2467548,"name":"Neuropsychological Tests","url":"https://www.academia.edu/Documents/in/Neuropsychological_Tests?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_621634" data-work_id="621634" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/621634/Differences_in_cortical_activity_between_methamphetamine_dependent_and_healthy_individuals_performing_a_facial_affect_matching_task">Differences in cortical activity between methamphetamine-dependent and healthy individuals performing a facial affect matching task</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">As individuals who abuse methamphetamine (MA) often exhibit socially maladaptive behaviors such as violence and aggression, it is possible that they respond abnormally to social cues. To investigate this issue, we exposed 12 MA-dependent... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_621634" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">As individuals who abuse methamphetamine (MA) often exhibit socially maladaptive behaviors such as violence and aggression, it is possible that they respond abnormally to social cues. To investigate this issue, we exposed 12 MA-dependent participants (abstinent 5-16 days) and 12 healthy comparison participants to fearful and angry faces while they performed an affect matching task during functional magnetic resonance imaging (fMRI). Although the groups did not differ in task performance, the healthy participants showed more task-related activity than the MA-dependent participants in a set of cortical regions consisting of the ventrolateral prefrontal cortex (VLPFC), temporoparietal junction (TPJ), anterior and posterior temporal cortex, and fusiform gyrus in the right hemisphere, and the cuneus in the left hemisphere. In contrast, the MA-dependent participants showed more task-related activity than the healthy participants in the dorsal anterior cingulate cortex (dACC). As expected, the task elicited activation of the amygdala in both groups; however, contrary to expectation, we found no difference between groups in this activation. Dorsal ACC hyperactivity, along with high self-ratings of hostility and interpersonal sensitivity in the MA-dependent group, suggest a hyper-sensitivity to socially threatening cues in the MA-dependent participants, while lower VLPFC activation could point to a deficit in integrating socio-emotional information and/or regulating this limbic hyperactivity. Additional activation differences in neural circuitry related to social cognition (TPJ, anterior, and posterior temporal cortex) suggest further socio-emotional deficits. Together, the results point to cortical abnormalities that could underlie the socially inappropriate behaviors often shown by individuals who abuse MA.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/621634" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="09a903c76cf37f3f96f561ac8af9f149" rel="nofollow" data-download="{"attachment_id":51328052,"asset_id":621634,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/51328052/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="203951" href="https://ucla.academia.edu/MatthewLieberman">Matthew Lieberman</a><script data-card-contents-for-user="203951" type="text/json">{"id":203951,"first_name":"Matthew","last_name":"Lieberman","domain_name":"ucla","page_name":"MatthewLieberman","display_name":"Matthew Lieberman","profile_url":"https://ucla.academia.edu/MatthewLieberman?f_ri=57557","photo":"https://0.academia-photos.com/203951/259691/306839/s65_matthew.lieberman.jpg"}</script></span></span></li><li class="js-paper-rank-work_621634 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="621634"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 621634, container: ".js-paper-rank-work_621634", }); });</script></li><li class="js-percentile-work_621634 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 621634; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_621634"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_621634 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="621634"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 621634; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=621634]").text(description); $(".js-view-count-work_621634").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_621634").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="621634"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">32</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="635" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychiatry">Psychiatry</a>, <script data-card-contents-for-ri="635" type="text/json">{"id":635,"name":"Psychiatry","url":"https://www.academia.edu/Documents/in/Psychiatry?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="2483" rel="nofollow" href="https://www.academia.edu/Documents/in/Addiction">Addiction</a>, <script data-card-contents-for-ri="2483" type="text/json">{"id":2483,"name":"Addiction","url":"https://www.academia.edu/Documents/in/Addiction?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4626" rel="nofollow" href="https://www.academia.edu/Documents/in/Social_Cognition">Social Cognition</a><script data-card-contents-for-ri="4626" type="text/json">{"id":4626,"name":"Social Cognition","url":"https://www.academia.edu/Documents/in/Social_Cognition?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=621634]'), work: {"id":621634,"title":"Differences in cortical activity between methamphetamine-dependent and healthy individuals performing a facial affect matching task","created_at":"2011-05-27T06:41:07.245-07:00","url":"https://www.academia.edu/621634/Differences_in_cortical_activity_between_methamphetamine_dependent_and_healthy_individuals_performing_a_facial_affect_matching_task?f_ri=57557","dom_id":"work_621634","summary":"As individuals who abuse methamphetamine (MA) often exhibit socially maladaptive behaviors such as violence and aggression, it is possible that they respond abnormally to social cues. To investigate this issue, we exposed 12 MA-dependent participants (abstinent 5-16 days) and 12 healthy comparison participants to fearful and angry faces while they performed an affect matching task during functional magnetic resonance imaging (fMRI). Although the groups did not differ in task performance, the healthy participants showed more task-related activity than the MA-dependent participants in a set of cortical regions consisting of the ventrolateral prefrontal cortex (VLPFC), temporoparietal junction (TPJ), anterior and posterior temporal cortex, and fusiform gyrus in the right hemisphere, and the cuneus in the left hemisphere. In contrast, the MA-dependent participants showed more task-related activity than the healthy participants in the dorsal anterior cingulate cortex (dACC). As expected, the task elicited activation of the amygdala in both groups; however, contrary to expectation, we found no difference between groups in this activation. Dorsal ACC hyperactivity, along with high self-ratings of hostility and interpersonal sensitivity in the MA-dependent group, suggest a hyper-sensitivity to socially threatening cues in the MA-dependent participants, while lower VLPFC activation could point to a deficit in integrating socio-emotional information and/or regulating this limbic hyperactivity. Additional activation differences in neural circuitry related to social cognition (TPJ, anterior, and posterior temporal cortex) suggest further socio-emotional deficits. Together, the results point to cortical abnormalities that could underlie the socially inappropriate behaviors often shown by individuals who abuse MA.","downloadable_attachments":[{"id":51328052,"asset_id":621634,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":203951,"first_name":"Matthew","last_name":"Lieberman","domain_name":"ucla","page_name":"MatthewLieberman","display_name":"Matthew Lieberman","profile_url":"https://ucla.academia.edu/MatthewLieberman?f_ri=57557","photo":"https://0.academia-photos.com/203951/259691/306839/s65_matthew.lieberman.jpg"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true},{"id":635,"name":"Psychiatry","url":"https://www.academia.edu/Documents/in/Psychiatry?f_ri=57557","nofollow":true},{"id":2483,"name":"Addiction","url":"https://www.academia.edu/Documents/in/Addiction?f_ri=57557","nofollow":true},{"id":4626,"name":"Social Cognition","url":"https://www.academia.edu/Documents/in/Social_Cognition?f_ri=57557","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557"},{"id":11636,"name":"Face","url":"https://www.academia.edu/Documents/in/Face?f_ri=57557"},{"id":12478,"name":"Emotion Regulation","url":"https://www.academia.edu/Documents/in/Emotion_Regulation?f_ri=57557"},{"id":18440,"name":"Social Perception","url":"https://www.academia.edu/Documents/in/Social_Perception?f_ri=57557"},{"id":21269,"name":"Facial expression","url":"https://www.academia.edu/Documents/in/Facial_expression?f_ri=57557"},{"id":23890,"name":"Comparative Study","url":"https://www.academia.edu/Documents/in/Comparative_Study?f_ri=57557"},{"id":28576,"name":"Prefrontal Cortex","url":"https://www.academia.edu/Documents/in/Prefrontal_Cortex?f_ri=57557"},{"id":50238,"name":"Affect","url":"https://www.academia.edu/Documents/in/Affect?f_ri=57557"},{"id":54755,"name":"Right Hemisphere Functions","url":"https://www.academia.edu/Documents/in/Right_Hemisphere_Functions?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":84743,"name":"Faces","url":"https://www.academia.edu/Documents/in/Faces?f_ri=57557"},{"id":100292,"name":"Methamphetamine","url":"https://www.academia.edu/Documents/in/Methamphetamine?f_ri=57557"},{"id":100946,"name":"Functional Imaging","url":"https://www.academia.edu/Documents/in/Functional_Imaging?f_ri=57557"},{"id":129428,"name":"Drug Addiction","url":"https://www.academia.edu/Documents/in/Drug_Addiction?f_ri=57557"},{"id":130136,"name":"Autoregulation","url":"https://www.academia.edu/Documents/in/Autoregulation?f_ri=57557"},{"id":206590,"name":"Task Performance","url":"https://www.academia.edu/Documents/in/Task_Performance?f_ri=57557"},{"id":207162,"name":"Temporal Cortex","url":"https://www.academia.edu/Documents/in/Temporal_Cortex?f_ri=57557"},{"id":232534,"name":"Health Status","url":"https://www.academia.edu/Documents/in/Health_Status?f_ri=57557"},{"id":322549,"name":"Activity","url":"https://www.academia.edu/Documents/in/Activity?f_ri=57557"},{"id":406036,"name":"Parietal Lobe","url":"https://www.academia.edu/Documents/in/Parietal_Lobe?f_ri=57557"},{"id":461381,"name":"Dorsal Anterior Cingulate Cortex","url":"https://www.academia.edu/Documents/in/Dorsal_Anterior_Cingulate_Cortex?f_ri=57557"},{"id":613642,"name":"Fusiform Gyrus","url":"https://www.academia.edu/Documents/in/Fusiform_Gyrus?f_ri=57557"},{"id":810789,"name":"Left Hemisphere","url":"https://www.academia.edu/Documents/in/Left_Hemisphere?f_ri=57557"},{"id":1024379,"name":"Nuclear Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Nuclear_Magnetic_Resonance_Imaging?f_ri=57557"},{"id":1423077,"name":"Substance-Related Disorders","url":"https://www.academia.edu/Documents/in/Substance-Related_Disorders?f_ri=57557"},{"id":1627527,"name":"Cognition disorders","url":"https://www.academia.edu/Documents/in/Cognition_disorders?f_ri=57557"},{"id":2234200,"name":"Functional Laterality","url":"https://www.academia.edu/Documents/in/Functional_Laterality?f_ri=57557"},{"id":2467548,"name":"Neuropsychological Tests","url":"https://www.academia.edu/Documents/in/Neuropsychological_Tests?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_1495323" data-work_id="1495323" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/1495323/Neural_responses_to_morphological_syntactic_and_semantic_properties_of_single_words_An_fMRI_study">Neural responses to morphological, syntactic, and semantic properties of single words: An fMRI study</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Dissociations in the recognition of specific classes of words have been documented in brain-injured populations. These include deficits in the recognition and production of morphologically complex words as well as impairments specific to... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_1495323" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Dissociations in the recognition of specific classes of words have been documented in brain-injured populations. These include deficits in the recognition and production of morphologically complex words as well as impairments specific to particular syntactic classes such as verbs. However, functional imaging evidence for distinctions among the neural systems underlying these dissociations has been inconclusive. We explored the neural systems involved in processing different word classes in a functional Magnetic Resonance Imaging study, contrasting four groups of words co-varying morphological complexity (simple, monomorphemic words vs complex derived or inflected words) and syntactic class (verbs vs nouns/adjectives). Subtraction of word from letter string processing showed activation in left frontal and temporal lobe regions consistent with prior studies of visual word processing. No differences were observed for morphologically complex and simple words, despite adequate power to detect stimulus specific effects. A region of posterior left middle temporal gyrus showed significantly increased activation for verbs. Post hoc analyses showed that this elevated activation could also be related to semantic properties of the stimulus items (verbs have stronger action associations than nouns, and action association is correlated with activation). Results suggest that semantic as well as syntactic factors should be considered when assessing the neural systems involved in single word comprehension.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/1495323" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="1aee8ac989b78c9440533fc2afa7af8a" rel="nofollow" data-download="{"attachment_id":50949059,"asset_id":1495323,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/50949059/download_file?st=MTc0MDE0MDM0Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="1421314" href="https://cnrs.academia.edu/FannyMeunier">Fanny Meunier</a><script data-card-contents-for-user="1421314" type="text/json">{"id":1421314,"first_name":"Fanny","last_name":"Meunier","domain_name":"cnrs","page_name":"FannyMeunier","display_name":"Fanny Meunier","profile_url":"https://cnrs.academia.edu/FannyMeunier?f_ri=57557","photo":"https://0.academia-photos.com/1421314/512253/643333/s65_fanny.meunier.jpg"}</script></span></span></li><li class="js-paper-rank-work_1495323 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="1495323"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 1495323, container: ".js-paper-rank-work_1495323", }); });</script></li><li class="js-percentile-work_1495323 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 1495323; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_1495323"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_1495323 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="1495323"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 1495323; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=1495323]").text(description); $(".js-view-count-work_1495323").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_1495323").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="1495323"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">20</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="2349" rel="nofollow" href="https://www.academia.edu/Documents/in/Semantics">Semantics</a>, <script data-card-contents-for-ri="2349" type="text/json">{"id":2349,"name":"Semantics","url":"https://www.academia.edu/Documents/in/Semantics?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4972" rel="nofollow" href="https://www.academia.edu/Documents/in/Psycholinguistics">Psycholinguistics</a>, <script data-card-contents-for-ri="4972" type="text/json">{"id":4972,"name":"Psycholinguistics","url":"https://www.academia.edu/Documents/in/Psycholinguistics?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="5391" rel="nofollow" href="https://www.academia.edu/Documents/in/Speech_perception">Speech perception</a>, <script data-card-contents-for-ri="5391" type="text/json">{"id":5391,"name":"Speech perception","url":"https://www.academia.edu/Documents/in/Speech_perception?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a><script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=1495323]'), work: {"id":1495323,"title":"Neural responses to morphological, syntactic, and semantic properties of single words: An fMRI study","created_at":"2012-04-02T01:05:12.476-07:00","url":"https://www.academia.edu/1495323/Neural_responses_to_morphological_syntactic_and_semantic_properties_of_single_words_An_fMRI_study?f_ri=57557","dom_id":"work_1495323","summary":"Dissociations in the recognition of specific classes of words have been documented in brain-injured populations. These include deficits in the recognition and production of morphologically complex words as well as impairments specific to particular syntactic classes such as verbs. However, functional imaging evidence for distinctions among the neural systems underlying these dissociations has been inconclusive. We explored the neural systems involved in processing different word classes in a functional Magnetic Resonance Imaging study, contrasting four groups of words co-varying morphological complexity (simple, monomorphemic words vs complex derived or inflected words) and syntactic class (verbs vs nouns/adjectives). Subtraction of word from letter string processing showed activation in left frontal and temporal lobe regions consistent with prior studies of visual word processing. No differences were observed for morphologically complex and simple words, despite adequate power to detect stimulus specific effects. A region of posterior left middle temporal gyrus showed significantly increased activation for verbs. Post hoc analyses showed that this elevated activation could also be related to semantic properties of the stimulus items (verbs have stronger action associations than nouns, and action association is correlated with activation). Results suggest that semantic as well as syntactic factors should be considered when assessing the neural systems involved in single word comprehension.","downloadable_attachments":[{"id":50949059,"asset_id":1495323,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":1421314,"first_name":"Fanny","last_name":"Meunier","domain_name":"cnrs","page_name":"FannyMeunier","display_name":"Fanny Meunier","profile_url":"https://cnrs.academia.edu/FannyMeunier?f_ri=57557","photo":"https://0.academia-photos.com/1421314/512253/643333/s65_fanny.meunier.jpg"}],"research_interests":[{"id":2349,"name":"Semantics","url":"https://www.academia.edu/Documents/in/Semantics?f_ri=57557","nofollow":true},{"id":4972,"name":"Psycholinguistics","url":"https://www.academia.edu/Documents/in/Psycholinguistics?f_ri=57557","nofollow":true},{"id":5391,"name":"Speech perception","url":"https://www.academia.edu/Documents/in/Speech_perception?f_ri=57557","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":10866,"name":"Morphology","url":"https://www.academia.edu/Documents/in/Morphology?f_ri=57557"},{"id":18174,"name":"Language","url":"https://www.academia.edu/Documents/in/Language?f_ri=57557"},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=57557"},{"id":28411,"name":"Inflection","url":"https://www.academia.edu/Documents/in/Inflection?f_ri=57557"},{"id":52176,"name":"Brain Mapping","url":"https://www.academia.edu/Documents/in/Brain_Mapping?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":64692,"name":"Derivation","url":"https://www.academia.edu/Documents/in/Derivation?f_ri=57557"},{"id":90515,"name":"Word Recognition","url":"https://www.academia.edu/Documents/in/Word_Recognition?f_ri=57557"},{"id":100946,"name":"Functional Imaging","url":"https://www.academia.edu/Documents/in/Functional_Imaging?f_ri=57557"},{"id":144935,"name":"Nouns","url":"https://www.academia.edu/Documents/in/Nouns?f_ri=57557"},{"id":154527,"name":"Noun","url":"https://www.academia.edu/Documents/in/Noun?f_ri=57557"},{"id":235085,"name":"Semantic Processing","url":"https://www.academia.edu/Documents/in/Semantic_Processing?f_ri=57557"},{"id":595278,"name":"Word Processing","url":"https://www.academia.edu/Documents/in/Word_Processing?f_ri=57557"},{"id":967583,"name":"Lexical Processing","url":"https://www.academia.edu/Documents/in/Lexical_Processing?f_ri=57557"},{"id":1257483,"name":"Frontal Lobe","url":"https://www.academia.edu/Documents/in/Frontal_Lobe?f_ri=57557"},{"id":1443732,"name":"Diagnostic Tests","url":"https://www.academia.edu/Documents/in/Diagnostic_Tests?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_17392372 coauthored" data-work_id="17392372" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/17392372/Early_hominid_brain_evolution_a_new_look_at_old_endocasts">Early hominid brain evolution: a new look at old endocasts</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Early hominid brain morphology is reassessed from endocasts of Australopithecus africanus and three species of Paranthropus, and new endocast reconstructions and cranial capacities are reported for four key specimens from the Paranthropus... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_17392372" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Early hominid brain morphology is reassessed from endocasts of Australopithecus africanus and three species of Paranthropus, and new endocast reconstructions and cranial capacities are reported for four key specimens from the Paranthropus clade. The brain morphology of Australopithecus africanus appears more human like than that of Paranthropus in terms of overall frontal and temporal lobe shape. These new data do not support the proposal that increased encephalization is a shared feature between Paranthropus and early Homo. Our findings are consistent with the hypothesis that Australopithecus africanus could have been ancestral to Homo, and have implications for assessing the tempo and mode of early hominid neurological and cognitive evolution.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/17392372" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="4e7f20b250fcbe6db9ed1dc125fd7ad1" rel="nofollow" data-download="{"attachment_id":42263410,"asset_id":17392372,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42263410/download_file?st=MTc0MDE0MDM0OCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="37119515" href="https://independent.academia.edu/WolfgangRecheis">Wolfgang Recheis</a><script data-card-contents-for-user="37119515" type="text/json">{"id":37119515,"first_name":"Wolfgang","last_name":"Recheis","domain_name":"independent","page_name":"WolfgangRecheis","display_name":"Wolfgang Recheis","profile_url":"https://independent.academia.edu/WolfgangRecheis?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-17392372">+1</span><div class="hidden js-additional-users-17392372"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/HorstSeidler">Horst Seidler</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-17392372'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-17392372').html(); 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container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_17392372 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="17392372"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17392372; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17392372]").text(description); $(".js-view-count-work_17392372").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_17392372").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="17392372"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">12</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="155" rel="nofollow" href="https://www.academia.edu/Documents/in/Evolutionary_Biology">Evolutionary Biology</a>, <script data-card-contents-for-ri="155" type="text/json">{"id":155,"name":"Evolutionary Biology","url":"https://www.academia.edu/Documents/in/Evolutionary_Biology?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="392" rel="nofollow" href="https://www.academia.edu/Documents/in/Archaeology">Archaeology</a>, <script data-card-contents-for-ri="392" type="text/json">{"id":392,"name":"Archaeology","url":"https://www.academia.edu/Documents/in/Archaeology?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="767" rel="nofollow" href="https://www.academia.edu/Documents/in/Anthropology">Anthropology</a>, <script data-card-contents-for-ri="767" type="text/json">{"id":767,"name":"Anthropology","url":"https://www.academia.edu/Documents/in/Anthropology?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="772" rel="nofollow" href="https://www.academia.edu/Documents/in/Human_Evolution">Human Evolution</a><script data-card-contents-for-ri="772" type="text/json">{"id":772,"name":"Human Evolution","url":"https://www.academia.edu/Documents/in/Human_Evolution?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=17392372]'), work: {"id":17392372,"title":"Early hominid brain evolution: a new look at old endocasts","created_at":"2015-10-27T23:58:20.520-07:00","url":"https://www.academia.edu/17392372/Early_hominid_brain_evolution_a_new_look_at_old_endocasts?f_ri=57557","dom_id":"work_17392372","summary":"Early hominid brain morphology is reassessed from endocasts of Australopithecus africanus and three species of Paranthropus, and new endocast reconstructions and cranial capacities are reported for four key specimens from the Paranthropus clade. The brain morphology of Australopithecus africanus appears more human like than that of Paranthropus in terms of overall frontal and temporal lobe shape. These new data do not support the proposal that increased encephalization is a shared feature between Paranthropus and early Homo. Our findings are consistent with the hypothesis that Australopithecus africanus could have been ancestral to Homo, and have implications for assessing the tempo and mode of early hominid neurological and cognitive evolution.","downloadable_attachments":[{"id":42263410,"asset_id":17392372,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":37119515,"first_name":"Wolfgang","last_name":"Recheis","domain_name":"independent","page_name":"WolfgangRecheis","display_name":"Wolfgang Recheis","profile_url":"https://independent.academia.edu/WolfgangRecheis?f_ri=57557","photo":"/images/s65_no_pic.png"},{"id":42642874,"first_name":"Horst","last_name":"Seidler","domain_name":"independent","page_name":"HorstSeidler","display_name":"Horst Seidler","profile_url":"https://independent.academia.edu/HorstSeidler?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":155,"name":"Evolutionary Biology","url":"https://www.academia.edu/Documents/in/Evolutionary_Biology?f_ri=57557","nofollow":true},{"id":392,"name":"Archaeology","url":"https://www.academia.edu/Documents/in/Archaeology?f_ri=57557","nofollow":true},{"id":767,"name":"Anthropology","url":"https://www.academia.edu/Documents/in/Anthropology?f_ri=57557","nofollow":true},{"id":772,"name":"Human Evolution","url":"https://www.academia.edu/Documents/in/Human_Evolution?f_ri=57557","nofollow":true},{"id":56971,"name":"Brain evolution","url":"https://www.academia.edu/Documents/in/Brain_evolution?f_ri=57557"},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain?f_ri=57557"},{"id":191815,"name":"Biological evolution","url":"https://www.academia.edu/Documents/in/Biological_evolution?f_ri=57557"},{"id":311472,"name":"Pan troglodytes","url":"https://www.academia.edu/Documents/in/Pan_troglodytes?f_ri=57557"},{"id":519447,"name":"Hominidae","url":"https://www.academia.edu/Documents/in/Hominidae?f_ri=57557"},{"id":1257483,"name":"Frontal Lobe","url":"https://www.academia.edu/Documents/in/Frontal_Lobe?f_ri=57557"},{"id":1624062,"name":"Pan Paniscus","url":"https://www.academia.edu/Documents/in/Pan_Paniscus?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_16889395" data-work_id="16889395" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/16889395/Ganglioglioma_of_the_Optic_Chiasm_Case_Report_and_Review_of_the_Literature">Ganglioglioma of the Optic Chiasm: Case Report and Review of the Literature</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Summary: We report a case of a hypothalamic chiasmatic ganglioglioma in a 21-year-old woman who presented with hyperprolactinemia and developed visual field defects. This circumscribed cystic lesion with an enhancing mural nod- ule was... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_16889395" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Summary: We report a case of a hypothalamic chiasmatic ganglioglioma in a 21-year-old woman who presented with hyperprolactinemia and developed visual field defects. This circumscribed cystic lesion with an enhancing mural nod- ule was radiologically indistinguishable from a pilocytic as- trocytoma. Although rare, gangliogliomas should be in- cluded in the differential diagnosis of lesions occurring in this area of the brain. Gangliogliomas, although relatively rare, are the most frequently occurring mixed glioneuronal tu- mors of the CNS (1). Their incidence ranges from 0.4% to 1.3% of all brain tumors, but they are more common in the pediatric group, with an incidence of 7.6% (2, 3). Patients usually present with sei- zures (2). The temporal lobes are the most common site, but gangliogliomas can occur anywhere in the central neuraxis, including the brain stem and spi- nal cord (1). We report a case of a ganglioglioma arising in the hypothalamic chiasmatic region and its MR imaging...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/16889395" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="6e1824d1ff446d312123a7a4727fe961" rel="nofollow" data-download="{"attachment_id":39240545,"asset_id":16889395,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/39240545/download_file?st=MTc0MDE0MDM0OCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="36370044" href="https://chula.academia.edu/ShanopShuangshoti">Shanop Shuangshoti</a><script data-card-contents-for-user="36370044" type="text/json">{"id":36370044,"first_name":"Shanop","last_name":"Shuangshoti","domain_name":"chula","page_name":"ShanopShuangshoti","display_name":"Shanop Shuangshoti","profile_url":"https://chula.academia.edu/ShanopShuangshoti?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_16889395 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="16889395"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 16889395, container: ".js-paper-rank-work_16889395", }); 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$(".js-view-count[data-work-id=16889395]").text(description); $(".js-view-count-work_16889395").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_16889395").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="16889395"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">20</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="650" rel="nofollow" href="https://www.academia.edu/Documents/in/Neurosurgery">Neurosurgery</a>, <script data-card-contents-for-ri="650" type="text/json">{"id":650,"name":"Neurosurgery","url":"https://www.academia.edu/Documents/in/Neurosurgery?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="40271" rel="nofollow" href="https://www.academia.edu/Documents/in/Visual_acuity">Visual acuity</a>, <script data-card-contents-for-ri="40271" type="text/json">{"id":40271,"name":"Visual acuity","url":"https://www.academia.edu/Documents/in/Visual_acuity?f_ri=57557","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="51883" rel="nofollow" href="https://www.academia.edu/Documents/in/Brain_Tumor">Brain Tumor</a><script data-card-contents-for-ri="51883" type="text/json">{"id":51883,"name":"Brain Tumor","url":"https://www.academia.edu/Documents/in/Brain_Tumor?f_ri=57557","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=16889395]'), work: {"id":16889395,"title":"Ganglioglioma of the Optic Chiasm: Case Report and Review of the Literature","created_at":"2015-10-16T15:33:33.501-07:00","url":"https://www.academia.edu/16889395/Ganglioglioma_of_the_Optic_Chiasm_Case_Report_and_Review_of_the_Literature?f_ri=57557","dom_id":"work_16889395","summary":"Summary: We report a case of a hypothalamic chiasmatic ganglioglioma in a 21-year-old woman who presented with hyperprolactinemia and developed visual field defects. This circumscribed cystic lesion with an enhancing mural nod- ule was radiologically indistinguishable from a pilocytic as- trocytoma. Although rare, gangliogliomas should be in- cluded in the differential diagnosis of lesions occurring in this area of the brain. Gangliogliomas, although relatively rare, are the most frequently occurring mixed glioneuronal tu- mors of the CNS (1). Their incidence ranges from 0.4% to 1.3% of all brain tumors, but they are more common in the pediatric group, with an incidence of 7.6% (2, 3). Patients usually present with sei- zures (2). The temporal lobes are the most common site, but gangliogliomas can occur anywhere in the central neuraxis, including the brain stem and spi- nal cord (1). We report a case of a ganglioglioma arising in the hypothalamic chiasmatic region and its MR imaging...","downloadable_attachments":[{"id":39240545,"asset_id":16889395,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":36370044,"first_name":"Shanop","last_name":"Shuangshoti","domain_name":"chula","page_name":"ShanopShuangshoti","display_name":"Shanop Shuangshoti","profile_url":"https://chula.academia.edu/ShanopShuangshoti?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":650,"name":"Neurosurgery","url":"https://www.academia.edu/Documents/in/Neurosurgery?f_ri=57557","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=57557","nofollow":true},{"id":40271,"name":"Visual acuity","url":"https://www.academia.edu/Documents/in/Visual_acuity?f_ri=57557","nofollow":true},{"id":51883,"name":"Brain Tumor","url":"https://www.academia.edu/Documents/in/Brain_Tumor?f_ri=57557","nofollow":true},{"id":57557,"name":"Temporal Lobe","url":"https://www.academia.edu/Documents/in/Temporal_Lobe?f_ri=57557"},{"id":63886,"name":"Case Report","url":"https://www.academia.edu/Documents/in/Case_Report?f_ri=57557"},{"id":71422,"name":"Optic Nerve","url":"https://www.academia.edu/Documents/in/Optic_Nerve?f_ri=57557"},{"id":95704,"name":"Hypothalamus","url":"https://www.academia.edu/Documents/in/Hypothalamus?f_ri=57557"},{"id":130116,"name":"Astrocyte","url":"https://www.academia.edu/Documents/in/Astrocyte?f_ri=57557"},{"id":135363,"name":"Visual Impairment","url":"https://www.academia.edu/Documents/in/Visual_Impairment?f_ri=57557"},{"id":151448,"name":"American","url":"https://www.academia.edu/Documents/in/American?f_ri=57557"},{"id":162159,"name":"Differential Diagnosis","url":"https://www.academia.edu/Documents/in/Differential_Diagnosis?f_ri=57557"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=57557"},{"id":256805,"name":"Neuroblastoma","url":"https://www.academia.edu/Documents/in/Neuroblastoma?f_ri=57557"},{"id":293670,"name":"Pituitary Gland","url":"https://www.academia.edu/Documents/in/Pituitary_Gland?f_ri=57557"},{"id":914074,"name":"Visual Field","url":"https://www.academia.edu/Documents/in/Visual_Field?f_ri=57557"},{"id":1122411,"name":"Mr Imaging","url":"https://www.academia.edu/Documents/in/Mr_Imaging?f_ri=57557"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=57557"},{"id":1250577,"name":"Gray Matter","url":"https://www.academia.edu/Documents/in/Gray_Matter?f_ri=57557"},{"id":2004746,"name":"Spin Echo","url":"https://www.academia.edu/Documents/in/Spin_Echo?f_ri=57557"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_16844325" data-work_id="16844325" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/16844325/Effects_of_aging_and_divided_attention_on_memory_for_items_and_their_contexts">Effects of aging and divided attention on memory for items and their contexts</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">It is commonly found that memory for context declines disproportionately with aging, arguably due to a general age-related deficit in associative memory processes. One possible mechanism for such deficits is an age-related reduction in... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_16844325" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">It is commonly found that memory for context declines disproportionately with aging, arguably due to a general age-related deficit in associative memory processes. One possible mechanism for such deficits is an age-related reduction in available processing resources. In two experiments we compared the effects of aging to the effects of division of attention in younger adults on memory for items and context. Using a technique proposed by Craik (1989), linear functions relating memory performance for items and their contexts were derived for a Young Full Attention group, a Young Divided Attention group, and an Older Adult group. Results suggested that the Old group showed an additional deficit in associative memory that was not mimicked by divided attention. It is speculated that both divided attention and aging are associated with a loss of available processing resources that may reflect inefficient frontal lobe functioning, whereas the additional age-related decrement in associative...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/16844325" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a923da33e3fa6d6abfb63b718f39c11c" rel="nofollow" data-download="{"attachment_id":42385459,"asset_id":16844325,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42385459/download_file?st=MTc0MDE0MDM0OCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="36303755" href="https://independent.academia.edu/FergusCraik">Fergus Craik</a><script data-card-contents-for-user="36303755" type="text/json">{"id":36303755,"first_name":"Fergus","last_name":"Craik","domain_name":"independent","page_name":"FergusCraik","display_name":"Fergus Craik","profile_url":"https://independent.academia.edu/FergusCraik?f_ri=57557","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_16844325 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="16844325"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 16844325, container: ".js-paper-rank-work_16844325", }); 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One possible mechanism for such deficits is an age-related reduction in available processing resources. In two experiments we compared the effects of aging to the effects of division of attention in younger adults on memory for items and context. Using a technique proposed by Craik (1989), linear functions relating memory performance for items and their contexts were derived for a Young Full Attention group, a Young Divided Attention group, and an Older Adult group. Results suggested that the Old group showed an additional deficit in associative memory that was not mimicked by divided attention. It is speculated that both divided attention and aging are associated with a loss of available processing resources that may reflect inefficient frontal lobe functioning, whereas the additional age-related decrement in associative...","downloadable_attachments":[{"id":42385459,"asset_id":16844325,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":36303755,"first_name":"Fergus","last_name":"Craik","domain_name":"independent","page_name":"FergusCraik","display_name":"Fergus Craik","profile_url":"https://independent.academia.edu/FergusCraik?f_ri=57557","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=57557","nofollow":true},{"id":237,"name":"Cognitive 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