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Beskikbaar in 51 tale" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-51" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">51 tale</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D9%85%D8%B3%D8%AA%D9%82%D8%A8%D9%84_(%D9%83%D9%8A%D9%85%D9%8A%D8%A7%D8%A1_%D8%AD%D9%8A%D9%88%D9%8A%D8%A9)" title="مستقبل (كيمياء حيوية) – Arabies" lang="ar" hreflang="ar" data-title="مستقبل (كيمياء حيوية)" data-language-autonym="العربية" data-language-local-name="Arabies" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Receptor_(biohemija)" title="Receptor (biohemija) – Bosnies" lang="bs" hreflang="bs" data-title="Receptor (biohemija)" data-language-autonym="Bosanski" data-language-local-name="Bosnies" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Receptor_(bioqu%C3%ADmica)" title="Receptor (bioquímica) – Katalaans" lang="ca" hreflang="ca" data-title="Receptor (bioquímica)" data-language-autonym="Català" data-language-local-name="Katalaans" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Receptor" title="Receptor – Tsjeggies" lang="cs" hreflang="cs" data-title="Receptor" data-language-autonym="Čeština" data-language-local-name="Tsjeggies" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-da mw-list-item"><a href="https://da.wikipedia.org/wiki/Receptor" title="Receptor – Deens" lang="da" hreflang="da" data-title="Receptor" data-language-autonym="Dansk" data-language-local-name="Deens" class="interlanguage-link-target"><span>Dansk</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Rezeptor_(Biochemie)" title="Rezeptor (Biochemie) – Duits" lang="de" hreflang="de" data-title="Rezeptor (Biochemie)" data-language-autonym="Deutsch" data-language-local-name="Duits" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Receptor_(biochemistry)" title="Receptor (biochemistry) – Engels" lang="en" hreflang="en" data-title="Receptor (biochemistry)" data-language-autonym="English" data-language-local-name="Engels" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-eo mw-list-item"><a href="https://eo.wikipedia.org/wiki/Ricevanto_(biologio)" title="Ricevanto (biologio) – Esperanto" lang="eo" hreflang="eo" data-title="Ricevanto (biologio)" data-language-autonym="Esperanto" data-language-local-name="Esperanto" class="interlanguage-link-target"><span>Esperanto</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Receptor_celular" title="Receptor celular – Spaans" lang="es" hreflang="es" data-title="Receptor celular" data-language-autonym="Español" data-language-local-name="Spaans" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-et mw-list-item"><a href="https://et.wikipedia.org/wiki/Retseptor_(biokeemia)" title="Retseptor (biokeemia) – Estnies" lang="et" hreflang="et" data-title="Retseptor (biokeemia)" data-language-autonym="Eesti" data-language-local-name="Estnies" class="interlanguage-link-target"><span>Eesti</span></a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/Hartzaile_(biokimika)" title="Hartzaile (biokimika) – Baskies" lang="eu" hreflang="eu" data-title="Hartzaile (biokimika)" data-language-autonym="Euskara" data-language-local-name="Baskies" class="interlanguage-link-target"><span>Euskara</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%DA%AF%DB%8C%D8%B1%D9%86%D8%AF%D9%87_(%D8%A8%DB%8C%D9%88%D8%B4%DB%8C%D9%85%DB%8C)" title="گیرنده (بیوشیمی) – Persies" lang="fa" hreflang="fa" data-title="گیرنده (بیوشیمی)" data-language-autonym="فارسی" data-language-local-name="Persies" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Reseptori_(biokemia)" title="Reseptori (biokemia) – Fins" lang="fi" hreflang="fi" data-title="Reseptori (biokemia)" data-language-autonym="Suomi" data-language-local-name="Fins" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/R%C3%A9cepteur_(biochimie)" title="Récepteur (biochimie) – Frans" lang="fr" hreflang="fr" data-title="Récepteur (biochimie)" data-language-autonym="Français" data-language-local-name="Frans" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Receptor_(bioqu%C3%ADmica)" title="Receptor (bioquímica) – Galisies" lang="gl" hreflang="gl" data-title="Receptor (bioquímica)" data-language-autonym="Galego" data-language-local-name="Galisies" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%A7%D7%95%D7%9C%D7%98%D7%9F" title="קולטן – Hebreeus" lang="he" hreflang="he" data-title="קולטן" data-language-autonym="עברית" data-language-local-name="Hebreeus" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-hr mw-list-item"><a href="https://hr.wikipedia.org/wiki/Receptor" title="Receptor – Kroaties" lang="hr" hreflang="hr" data-title="Receptor" data-language-autonym="Hrvatski" data-language-local-name="Kroaties" class="interlanguage-link-target"><span>Hrvatski</span></a></li><li class="interlanguage-link interwiki-ht mw-list-item"><a href="https://ht.wikipedia.org/wiki/Resept%C3%A8" title="Reseptè – Haïtiaans" lang="ht" hreflang="ht" data-title="Reseptè" data-language-autonym="Kreyòl ayisyen" data-language-local-name="Haïtiaans" class="interlanguage-link-target"><span>Kreyòl ayisyen</span></a></li><li class="interlanguage-link interwiki-hu mw-list-item"><a href="https://hu.wikipedia.org/wiki/Receptor_(biok%C3%A9mia)" title="Receptor (biokémia) – Hongaars" lang="hu" hreflang="hu" data-title="Receptor (biokémia)" data-language-autonym="Magyar" data-language-local-name="Hongaars" class="interlanguage-link-target"><span>Magyar</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Reseptor_(biokimia)" title="Reseptor (biokimia) – Indonesies" lang="id" hreflang="id" data-title="Reseptor (biokimia)" data-language-autonym="Bahasa Indonesia" data-language-local-name="Indonesies" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Recettore_(biochimica)" title="Recettore (biochimica) – Italiaans" lang="it" hreflang="it" data-title="Recettore (biochimica)" data-language-autonym="Italiano" data-language-local-name="Italiaans" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E5%8F%97%E5%AE%B9%E4%BD%93" title="受容体 – Japannees" lang="ja" hreflang="ja" data-title="受容体" data-language-autonym="日本語" data-language-local-name="Japannees" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EC%88%98%EC%9A%A9%EC%B2%B4" title="수용체 – Koreaans" lang="ko" hreflang="ko" data-title="수용체" data-language-autonym="한국어" data-language-local-name="Koreaans" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-ku mw-list-item"><a href="https://ku.wikipedia.org/wiki/Wergir_(j%C3%AEnk%C3%AEmya)" title="Wergir (jînkîmya) – Koerdies" lang="ku" hreflang="ku" data-title="Wergir (jînkîmya)" data-language-autonym="Kurdî" data-language-local-name="Koerdies" class="interlanguage-link-target"><span>Kurdî</span></a></li><li class="interlanguage-link interwiki-lt mw-list-item"><a href="https://lt.wikipedia.org/wiki/Receptorius_(molekul%C4%97)" title="Receptorius (molekulė) – Litaus" lang="lt" hreflang="lt" data-title="Receptorius (molekulė)" data-language-autonym="Lietuvių" data-language-local-name="Litaus" class="interlanguage-link-target"><span>Lietuvių</span></a></li><li class="interlanguage-link interwiki-lv mw-list-item"><a href="https://lv.wikipedia.org/wiki/%C5%A0%C5%ABnu_receptors" title="Šūnu receptors – Letties" lang="lv" hreflang="lv" data-title="Šūnu receptors" data-language-autonym="Latviešu" data-language-local-name="Letties" class="interlanguage-link-target"><span>Latviešu</span></a></li><li class="interlanguage-link interwiki-mk mw-list-item"><a href="https://mk.wikipedia.org/wiki/%D0%A0%D0%B5%D1%86%D0%B5%D0%BF%D1%82%D0%BE%D1%80_(%D0%B1%D0%B8%D0%BE%D1%85%D0%B5%D0%BC%D0%B8%D1%98%D0%B0)" title="Рецептор (биохемија) – Masedonies" lang="mk" hreflang="mk" data-title="Рецептор (биохемија)" data-language-autonym="Македонски" data-language-local-name="Masedonies" class="interlanguage-link-target"><span>Македонски</span></a></li><li class="interlanguage-link interwiki-ml mw-list-item"><a href="https://ml.wikipedia.org/wiki/%E0%B4%B1%E0%B4%BF%E0%B4%B8%E0%B4%AA%E0%B5%8D%E0%B4%B1%E0%B5%8D%E0%B4%B1%E0%B5%BC_(%E0%B4%9C%E0%B5%88%E0%B4%B5%E0%B4%B0%E0%B4%B8%E0%B4%A4%E0%B4%A8%E0%B5%8D%E0%B4%A4%E0%B5%8D%E0%B4%B0%E0%B4%82)" title="റിസപ്റ്റർ (ജൈവരസതന്ത്രം) – Malabaars" lang="ml" hreflang="ml" data-title="റിസപ്റ്റർ (ജൈവരസതന്ത്രം)" data-language-autonym="മലയാളം" data-language-local-name="Malabaars" class="interlanguage-link-target"><span>മലയാളം</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Reseptor_(biokimia)" title="Reseptor (biokimia) – Maleis" lang="ms" hreflang="ms" data-title="Reseptor (biokimia)" data-language-autonym="Bahasa Melayu" data-language-local-name="Maleis" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Receptor_(biochemie)" title="Receptor (biochemie) – Nederlands" lang="nl" hreflang="nl" data-title="Receptor (biochemie)" data-language-autonym="Nederlands" data-language-local-name="Nederlands" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-no mw-list-item"><a href="https://no.wikipedia.org/wiki/Reseptor_(biokjemi)" title="Reseptor (biokjemi) – Boeknoors" lang="nb" hreflang="nb" data-title="Reseptor (biokjemi)" data-language-autonym="Norsk bokmål" data-language-local-name="Boeknoors" class="interlanguage-link-target"><span>Norsk bokmål</span></a></li><li class="interlanguage-link interwiki-oc mw-list-item"><a href="https://oc.wikipedia.org/wiki/Receptor_(bioquimia)" title="Receptor (bioquimia) – Oksitaans" lang="oc" hreflang="oc" data-title="Receptor (bioquimia)" data-language-autonym="Occitan" data-language-local-name="Oksitaans" class="interlanguage-link-target"><span>Occitan</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Bia%C5%82ka_receptorowe" title="Białka receptorowe – Pools" lang="pl" hreflang="pl" data-title="Białka receptorowe" data-language-autonym="Polski" data-language-local-name="Pools" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Receptor_(bioqu%C3%ADmica)" title="Receptor (bioquímica) – Portugees" lang="pt" hreflang="pt" data-title="Receptor (bioquímica)" data-language-autonym="Português" data-language-local-name="Portugees" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Receptor_(biochimie)" title="Receptor (biochimie) – Roemeens" lang="ro" hreflang="ro" data-title="Receptor (biochimie)" data-language-autonym="Română" data-language-local-name="Roemeens" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%9A%D0%BB%D0%B5%D1%82%D0%BE%D1%87%D0%BD%D1%8B%D0%B9_%D1%80%D0%B5%D1%86%D0%B5%D0%BF%D1%82%D0%BE%D1%80" title="Клеточный рецептор – Russies" lang="ru" hreflang="ru" data-title="Клеточный рецептор" data-language-autonym="Русский" data-language-local-name="Russies" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Receptor_(biohemija)" title="Receptor (biohemija) – Serwo-Kroaties" lang="sh" hreflang="sh" data-title="Receptor (biohemija)" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="Serwo-Kroaties" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-simple mw-list-item"><a href="https://simple.wikipedia.org/wiki/Receptor_(cell_biology)" title="Receptor (cell biology) – Simple English" lang="en-simple" hreflang="en-simple" data-title="Receptor (cell biology)" data-language-autonym="Simple English" data-language-local-name="Simple English" class="interlanguage-link-target"><span>Simple English</span></a></li><li class="interlanguage-link interwiki-sk mw-list-item"><a href="https://sk.wikipedia.org/wiki/Receptor_(fyziol%C3%B3gia)" title="Receptor (fyziológia) – Slowaaks" lang="sk" hreflang="sk" data-title="Receptor (fyziológia)" data-language-autonym="Slovenčina" data-language-local-name="Slowaaks" class="interlanguage-link-target"><span>Slovenčina</span></a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Receptor_(biokemija)" title="Receptor (biokemija) – Sloweens" lang="sl" hreflang="sl" data-title="Receptor (biokemija)" data-language-autonym="Slovenščina" data-language-local-name="Sloweens" class="interlanguage-link-target"><span>Slovenščina</span></a></li><li class="interlanguage-link interwiki-sq mw-list-item"><a href="https://sq.wikipedia.org/wiki/Receptori_(biokimi)" title="Receptori (biokimi) – Albanees" lang="sq" hreflang="sq" data-title="Receptori (biokimi)" data-language-autonym="Shqip" data-language-local-name="Albanees" class="interlanguage-link-target"><span>Shqip</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Receptor_(biohemija)" title="Receptor (biohemija) – Serwies" lang="sr" hreflang="sr" data-title="Receptor (biohemija)" data-language-autonym="Српски / srpski" data-language-local-name="Serwies" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Receptor" title="Receptor – Sweeds" lang="sv" hreflang="sv" data-title="Receptor" data-language-autonym="Svenska" data-language-local-name="Sweeds" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-th mw-list-item"><a href="https://th.wikipedia.org/wiki/%E0%B8%AB%E0%B8%99%E0%B9%88%E0%B8%A7%E0%B8%A2%E0%B8%A3%E0%B8%B1%E0%B8%9A%E0%B8%84%E0%B8%A7%E0%B8%B2%E0%B8%A1%E0%B8%A3%E0%B8%B9%E0%B9%89%E0%B8%AA%E0%B8%B6%E0%B8%81" title="หน่วยรับความรู้สึก – Thai" lang="th" hreflang="th" data-title="หน่วยรับความรู้สึก" data-language-autonym="ไทย" data-language-local-name="Thai" class="interlanguage-link-target"><span>ไทย</span></a></li><li class="interlanguage-link interwiki-tl mw-list-item"><a href="https://tl.wikipedia.org/wiki/Reseptor_(biokemistri)" title="Reseptor (biokemistri) – Tagalog" lang="tl" hreflang="tl" data-title="Reseptor (biokemistri)" data-language-autonym="Tagalog" 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class="mw-content-ltr mw-parser-output" lang="af" dir="ltr"><table class="infobox"> <caption>Struktuur van ’n tipiese chemiese sinaps </caption> <tbody><tr> <th style="background-color: #d0d0d0;">Reseptor </th></tr> <tr style="text-align: center"> <td><div style="position: relative;"><span typeof="mw:File"><a href="/wiki/L%C3%AAer:SynapseSchematic_lines.svg" class="mw-file-description"><img alt="An illustrated chemical synapse" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d7/SynapseSchematic_lines.svg/400px-SynapseSchematic_lines.svg.png" decoding="async" width="400" height="213" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d7/SynapseSchematic_lines.svg/600px-SynapseSchematic_lines.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d7/SynapseSchematic_lines.svg/800px-SynapseSchematic_lines.svg.png 2x" data-file-width="2000" data-file-height="1064" /></a></span> <div style="position: absolute; text-align: center; left:-1px; top: 160px;"><a href="/wiki/Sinaps" title="Sinaps">Postsinaptiese<br /> digtheid</a></div> <div style="position: absolute; text-align: center; left:6px; top: 87px;"><a href="/wiki/Aksiepotensiaal#Werking" title="Aksiepotensiaal"> Spannings-<br />beheerde Ca<sup>++</sup><br /> kanaal</a></div> <div style="position: absolute; text-align: center; left:19px; top: 42px;"><a href="/wiki/Sinaptiese_blasie" class="mw-redirect" title="Sinaptiese blasie">Sinaptiese<br /> blasie</a></div> <div style="position: absolute; text-align: center; left:206px; top: 22px;"><a href="/wiki/Senuoordraer" title="Senuoordraer">Senuoordraer-<br />vervoerder</a></div> <div style="position: absolute; text-align: center; left:250px; top: 153px;"><a class="mw-selflink selflink">Reseptor</a></div> <div style="position: absolute; text-align: center; left:8px; top: 7px;"><a href="/wiki/Senuoordraer" title="Senuoordraer">Senuoordraer</a></div> <div style="position: absolute; text-align: center; left:332px; top: 55px;"><a href="/wiki/Akson" title="Akson">Akson-<br />terminaal</a></div> <div style="position: absolute; text-align: center; left:330px; top: 137px;"><a href="/wiki/Sinaptiese_spleet" class="mw-redirect" title="Sinaptiese spleet">Sinaptiese spleet</a></div> <div style="position: absolute; text-align: center; left:342px; top: 182px;"><a href="/wiki/Dendriet" title="Dendriet">Dendriet</a></div></div> </td></tr></tbody></table> <figure class="mw-default-size mw-halign-left" typeof="mw:File/Thumb"><a href="/wiki/L%C3%AAer:Membrane_Receptors.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/b/be/Membrane_Receptors.svg/220px-Membrane_Receptors.svg.png" decoding="async" width="220" height="124" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/be/Membrane_Receptors.svg/330px-Membrane_Receptors.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/be/Membrane_Receptors.svg/440px-Membrane_Receptors.svg.png 2x" data-file-width="512" data-file-height="288" /></a><figcaption>Voorbeelde van membraanreseptore: 1. Ligande, 2. Reseptore, 3. Sekondêre boodskappers.</figcaption></figure> <p>’n <b>Reseptor</b> in <a href="/wiki/Biochemie" title="Biochemie">biochemie</a> en <a href="/w/index.php?title=Farmakologie&action=edit&redlink=1" class="new" title="Farmakologie (bladsy bestaan nie)">farmakologie</a> is ’n <a href="/wiki/Prote%C3%AFen" title="Proteïen">proteïen</a><a href="/wiki/Molekule" class="mw-redirect" title="Molekule">molekule</a> wat chemiese seine van ’n ander sel ontvang.<sup id="cite_ref-hall_1-0" class="reference"><a href="#cite_note-hall-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> Wanneer sulke chemiese seine aan ’n reseptor bind, veroorsaak hulle die een of ander vorm van weefsel-/sellulêre reaksie, byvoorbeeld ’n verandering in die sel se elektriese aktiwiteit. </p><p>In hierdie sin is ’n reseptor ’n proteïenmolekule wat interne chemiese seine herken en daarop reageer – ’n asetielcholien-reseptor herken byvoorbeeld sy interne <a href="/wiki/Ligand" title="Ligand">ligand</a>, <a href="/wiki/Asetielcholien" title="Asetielcholien">asetielcholien</a>. Soms word die term in farmakologie ook gebruik om ander proteïene in te sluit wat dwelmteikens is. </p><p>Reseptor<a href="/wiki/Prote%C3%AFen" title="Proteïen">proteïene</a> kan geklassifiseer word volgens hul ligging. Transmembraanreseptore sluit in ioonkanaalgebonde (ionotropiese) reseptore, G-proteïengebonde (metabotropiese) hormoonreseptore en ensiemgebonde hormoonreseptore.<sup id="cite_ref-hall_1-1" class="reference"><a href="#cite_note-hall-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> Intrasellulêre reseptore is dié wat in die sel voorkom en sluit in sitoplasmiese en kernreseptore.<sup id="cite_ref-hall_1-2" class="reference"><a href="#cite_note-hall-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> ’n Molukule wat aan ’n reseptor bind, word ’n ligand genoem; dit kan ’n proteïn, peptied of ander klein molekule wees soos ’n <a href="/wiki/Senuoordraer" title="Senuoordraer">senuoordraer</a>, <a href="/wiki/Hormoon" title="Hormoon">hormoon</a>, farmaseutiese <a href="/wiki/Dwelm" class="mw-redirect" title="Dwelm">dwelm</a>, gifstof of dele van die buitekant van ’n <a href="/wiki/Virus" title="Virus">virus</a> of mikrobe. Die intern aangewese molekule vir ’n spesifieke reseptor word sy interne ligand genoem. </p><p>Elke reseptor is gebonde aan ’n spesifieke sellulêre biochemiese pad. Hoewel verskeie reseptore in die meeste selle voorkom, sal elke reseptor net bind met ligande met ’n sekere struktuur, amper soos wat slegs ’n sleutel met ’n sekere vorm in ’n spesifieke slot sal pas. Wanneer ’n ligand met sy ooreenstemmende reseptor bind, aktiveer of inhibeer dit die reseptor se geassosieerde biochemiese pad. </p> <div class="mw-heading mw-heading2"><h2 id="Struktuur">Struktuur</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biochemie)&veaction=edit&section=1" title="Wysig afdeling: Struktuur" class="mw-editsection-visualeditor"><span>wysig</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biochemie)&action=edit&section=1" title="Edit section's source code: Struktuur"><span>wysig bron</span></a><span class="mw-editsection-bracket">]</span></span></div> <figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/L%C3%AAer:Transmembrane_receptor.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/4/48/Transmembrane_receptor.svg/220px-Transmembrane_receptor.svg.png" decoding="async" width="220" height="155" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/48/Transmembrane_receptor.svg/330px-Transmembrane_receptor.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/48/Transmembrane_receptor.svg/440px-Transmembrane_receptor.svg.png 2x" data-file-width="482" data-file-height="340" /></a><figcaption>Transmembraanreseptor:E=ekstrasellulêre ruimte; I=intrasellulêre ruimte; P=plasmamembraan.</figcaption></figure> <p>Reseptore se struktuur is baie uiteenlopend en kan oor die algemeen in die volgende kategorieë ingedeel word: </p> <ul><li>Tipe 1: L (ionotropiese reseptore) – gewoonlik die teikens van vinnige senuoordraers soos <a href="/wiki/Asetielcholien" title="Asetielcholien">asetielcholien</a> (nikotinies) en gamma-aminobottersuur (GABA); hul aktivering lei tot veranderings in ioonbeweging oor ’n membraan. Hulle het ’n heteromeriese struktuur in die sin dat elke ondereenheid bestaan uit die ekstrasellulêre ligandbindingsdomein en ’n transmembraandomein, waar laasgenoemde weer vier transmembraan-alfahelikse insluit. Die ligandbindingsholtes lê tussen die ondereenhede.</li> <li>Tipe 2: G-proteïengekoppelde reseptore (metabotropies) – die grootste groep reseptore; sluit in die reseptore vir verskeie hormone en stadige senuoordraers soos <a href="/wiki/Dopamien" title="Dopamien">dopamien</a>. Hulle is saamgestel uit sewe transmembraan-alfahelikse. Die lusse wat die alfahelikse verbind, vorm ekstra- en intrasellulêre domeine. Die bindingsplek vir groter peptiedligande is gewoonlik geleë in die ekstrasellulêre domein en die bindingsplek vir kleiner niepeptiedligande tussen die sewe alfahelikse en een ekstrasellulêre lus.<sup id="cite_ref-pmid19912230_2-0" class="reference"><a href="#cite_note-pmid19912230-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Die bogenoemde reseptore is gekoppel aan verskillende intrasellulêre effektorstelsels via G-proteïene.<sup id="cite_ref-pmid=21873996_3-0" class="reference"><a href="#cite_note-pmid=21873996-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup></li> <li>Tipe 3: Kinasegekoppelde en verwante reseptore – saamgestel uit ’n ekstrasellulêre domein, wat die ligandbindingsplek bevat, en ’n intrasellulêre domein. ’n Voorbeeld is die <a href="/wiki/Insulien" title="Insulien">insulienreseptor</a>.</li> <li>Tipe 4: Kernreseptore – ondanks hul naam lê hulle eintlik in die sitoplasma, en migreer na die selkern nadat hulle met hul ligande gebind het. Hulle is saamgestel uit ’n C-terminaal-ligandbindingstreek, ’n kern-DNS-bindingsdomein en ’n N-terminaaldomein wat die <i>AF1</i>(aktiveringsfunksie 1)-streek bevat.</li></ul> <div class="mw-heading mw-heading2"><h2 id="Verwysings">Verwysings</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biochemie)&veaction=edit&section=2" title="Wysig afdeling: Verwysings" class="mw-editsection-visualeditor"><span>wysig</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biochemie)&action=edit&section=2" title="Edit section's source code: Verwysings"><span>wysig bron</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="reflist" style="list-style-type: decimal;"> <ol class="references"> <li id="cite_note-hall-1"><span class="mw-cite-backlink">↑ <sup><a href="#cite_ref-hall_1-0">1,0</a></sup> <sup><a href="#cite_ref-hall_1-1">1,1</a></sup> <sup><a href="#cite_ref-hall_1-2">1,2</a></sup></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r2205490">.mw-parser-output cite.citation{font-style:inherit}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .id-lock-free a,.mw-parser-output .citation .cs1-lock-free a{background-image:url("//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png");background-image:linear-gradient(transparent,transparent),url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg");background-repeat:no-repeat;background-size:9px;background-position:right .1em center}.mw-parser-output .id-lock-limited a,.mw-parser-output .id-lock-registration a,.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration a{background-image:url("//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Lock-gray-alt-2.svg/9px-Lock-gray-alt-2.svg.png");background-image:linear-gradient(transparent,transparent),url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg");background-repeat:no-repeat;background-size:9px;background-position:right .1em center}.mw-parser-output .id-lock-subscription a,.mw-parser-output .citation .cs1-lock-subscription a{background-image:url("//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Lock-red-alt-2.svg/9px-Lock-red-alt-2.svg.png");background-image:linear-gradient(transparent,transparent),url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg");background-repeat:no-repeat;background-size:9px;background-position:right .1em center}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration{color:#555}.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration span{border-bottom:1px dotted;cursor:help}.mw-parser-output .cs1-ws-icon a{background-image:url("//upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Wikisource-logo.svg/12px-Wikisource-logo.svg.png");background-image:linear-gradient(transparent,transparent),url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg");background-repeat:no-repeat;background-size:12px;background-position:right .1em center}.mw-parser-output code.cs1-code{color:inherit;background:inherit;border:inherit;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;font-size:100%}.mw-parser-output .cs1-visible-error{font-size:100%}.mw-parser-output .cs1-maint{display:none;color:#33aa33;margin-left:0.3em}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-format{font-size:95%}.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}</style><cite id="CITEREFHall,_JE2016" class="citation book cs1">Hall, JE (2016). <i>Guyton and Hall Textbook of Medical Physiology</i>. Philadelphia, PA: Elsevier Saunders. pp. 930–937. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Spesiaal:Boekbronne/978-1-4557-7005-2" title="Spesiaal:Boekbronne/978-1-4557-7005-2"><bdi>978-1-4557-7005-2</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Guyton+and+Hall+Textbook+of+Medical+Physiology&rft.place=Philadelphia%2C+PA&rft.pages=930-937&rft.pub=Elsevier+Saunders&rft.date=2016&rft.isbn=978-1-4557-7005-2&rft.au=Hall%2C+JE&rfr_id=info%3Asid%2Faf.wikipedia.org%3AReseptor+%28biochemie%29" class="Z3988"></span></span> </li> <li id="cite_note-pmid19912230-2"><span class="mw-cite-backlink"><a href="#cite_ref-pmid19912230_2-0">↑</a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r2205490"><cite id="CITEREFCongreveMarshall2010" class="citation journal cs1">Congreve M, Marshall F (Maart 2010). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839258">"The impact of GPCR structures on pharmacology and structure-based drug design"</a>. <i>Br. J. Pharmacol</i>. <b>159</b> (5): 986–96. <a href="/wiki/Digitale_objek-identifiseerder" title="Digitale objek-identifiseerder">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fj.1476-5381.2009.00476.x">10.1111/j.1476-5381.2009.00476.x</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="cs1-lock-free" title="Vrylik beskikbaar"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839258">2839258</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/19912230">19912230</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Br.+J.+Pharmacol.&rft.atitle=The+impact+of+GPCR+structures+on+pharmacology+and+structure-based+drug+design&rft.volume=159&rft.issue=5&rft.pages=986-96&rft.date=2010-03&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2839258%23id-name%3DPMC&rft_id=info%3Apmid%2F19912230&rft_id=info%3Adoi%2F10.1111%2Fj.1476-5381.2009.00476.x&rft.aulast=Congreve&rft.aufirst=M&rft.au=Marshall%2C+F&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2839258&rfr_id=info%3Asid%2Faf.wikipedia.org%3AReseptor+%28biochemie%29" class="Z3988"></span></span> </li> <li id="cite_note-pmid=21873996-3"><span class="mw-cite-backlink"><a href="#cite_ref-pmid=21873996_3-0">↑</a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r2205490"><cite id="CITEREFKou_Qin,_Chunmin_Dong,_Guangyu_Wu_&_Nevin_A_Lambert2011" class="citation journal cs1">Kou Qin, Chunmin Dong, Guangyu Wu & Nevin A Lambert (Augustus 2011). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177959">"Inactive-state preassembly of Gq-coupled receptors and Gq heterotrimers"</a>. <i>Nature Chemical Biology</i>. <b>7</b> (11): 740–747. <a href="/wiki/Digitale_objek-identifiseerder" title="Digitale objek-identifiseerder">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fnchembio.642">10.1038/nchembio.642</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="cs1-lock-free" title="Vrylik beskikbaar"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177959">3177959</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/21873996">21873996</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature+Chemical+Biology&rft.atitle=Inactive-state+preassembly+of+Gq-coupled+receptors+and+Gq+heterotrimers&rft.volume=7&rft.issue=11&rft.pages=740-747&rft.date=2011-08&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3177959%23id-name%3DPMC&rft_id=info%3Apmid%2F21873996&rft_id=info%3Adoi%2F10.1038%2Fnchembio.642&rft.au=Kou+Qin%2C+Chunmin+Dong%2C+Guangyu+Wu+%26+Nevin+A+Lambert&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3177959&rfr_id=info%3Asid%2Faf.wikipedia.org%3AReseptor+%28biochemie%29" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Sjabloon:Cite_journal" title="Sjabloon:Cite journal">cite journal</a>}}</code>: AS1-onderhoud: meer as een naam (<a href="/wiki/Kategorie:AS1-onderhoud:_meer_as_een_naam" title="Kategorie:AS1-onderhoud: meer as een naam">link</a>)</span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="Eksterne_skakels">Eksterne skakels</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Reseptor_(biochemie)&veaction=edit&section=3" title="Wysig afdeling: Eksterne skakels" class="mw-editsection-visualeditor"><span>wysig</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Reseptor_(biochemie)&action=edit&section=3" title="Edit section's source code: Eksterne skakels"><span>wysig bron</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><span typeof="mw:File"><a href="/wiki/L%C3%AAer:Crystal_txt.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/8/83/Crystal_txt.png/15px-Crystal_txt.png" decoding="async" width="15" height="15" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/83/Crystal_txt.png/23px-Crystal_txt.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/83/Crystal_txt.png/30px-Crystal_txt.png 2x" data-file-width="64" data-file-height="64" /></a></span> Hierdie artikel is vertaal uit die <a href="https://en.wikipedia.org/wiki/Receptor_(biochemistry)" class="extiw" title="en:Receptor (biochemistry)">Engelse Wikipedia</a></li></ul>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">Ontsluit van "<a dir="ltr" href="https://af.wikipedia.org/w/index.php?title=Reseptor_(biochemie)&oldid=1884296">https://af.wikipedia.org/w/index.php?title=Reseptor_(biochemie)&oldid=1884296</a>"</div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/Spesiaal:Kategorie%C3%AB" title="Spesiaal:Kategorieë">Kategorie</a>: <ul><li><a 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