Kornblith Lab - Homepage

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<li class="menu-item menu-item--expanded"> <div role="group" aria-labelledby="Education&amp;Training" class="col"> <h2 id="Education&amp;Training" class="col-head" tabindex="0"> <span>Education & Training</span> </h2> <ul class="menu"> <li class="menu-item"> <a href="https://transplantfellowship.ucsf.edu/">Abdominal Transplant Fellowship</a> </li> <li class="menu-item"> <a href="https://surgeryfap.ucsf.edu/">Faculty Affairs & Development Portal</a> </li> <li class="menu-item"> <a href="https://medstudentsurgery.ucsf.edu/">Medical Student Portal</a> </li> <li class="menu-item"> <a href="https://murielsteelesociety.ucsf.edu/">Muriel Steele Society</a> </li> <li class="menu-item"> <a href="https://plasticsurgeryresidency.ucsf.edu/">Plastic Surgery Residency</a> </li> <li class="menu-item"> <a href="https://surgeryresidentportal.ucsf.edu/">Resident Portal</a> </li> <li class="menu-item"> <a href="https://surgeryresidentresearch.ucsf.edu/">Resident Research</a> </li> <li class="menu-item"> <a href="https://npfellowship.ucsf.edu/">Surgical & Critical Care NP Fellowship</a> </li> <li class="menu-item"> <a href="https://surgeryeducation.ucsf.edu/">Surgery Education Portal</a> </li> <li class="menu-item"> <a href="https://surgeryresearch.ucsf.edu/">Surgery Research Portal</a> </li> <li class="menu-item"> <a href="https://surgicalskillslab.ucsf.edu/">Surgical Skills Center</a> </li> <li class="menu-item"> <a href="https://thoracicsurgeryresidency.ucsf.edu/">Thoracic Surgery Residency</a> </li> <li class="menu-item"> <a href="https://t32surgicaloncology.ucsf.edu/">T32 Surgical Oncology</a> </li> <li class="menu-item"> <a href="https://t32transplantsurgery.ucsf.edu/">T32 Research Training in Transplant Surgery</a> </li> <li class="menu-item"> <a href="https://ucsf-eastbay.squarespace.com/">UCSF-East Bay General Surgery Residency</a> </li> <li class="menu-item"> <a href="https://vascularsurgeryresidency.ucsf.edu/">Vascular Surgery Integrated Residency Program</a> </li> </ul> </div> </li> <li class="menu-item menu-item--expanded"> <div role="group" aria-labelledby="ResearchWebsites" class="col"> <h2 id="ResearchWebsites" class="col-head" tabindex="0"> <span>Research Websites</span> </h2> <ul class="menu"> <li class="menu-item"> <a href="https://raffailab.ucsf.edu/">Atherosclerosis Research Lab</a> </li> <li class="menu-item"> <a href="https://surgerybiostat.ucsf.edu/">Biostatistics Core</a> </li> <li class="menu-item"> <a href="https://cardiacbiomechanicslab.ucsf.edu/">Cardiac Biomechanics Lab</a> </li> <li class="menu-item"> <a href="https://mindfulsurgeon.ucsf.edu/">Center for Mindfulness in Surgery</a> </li> <li class="menu-item"> <a href="https://livertissueengineering.ucsf.edu/">Chang Laboratory for Liver Tissue Engineering</a> </li> <li class="menu-item"> <a href="https://contelab.ucsf.edu/">Conte Lab</a> </li> <li class="menu-item"> <a href="https://endocrineneoplasialab.ucsf.edu/">Endocrine Neoplasia Research Lab</a> </li> <li class="menu-item"> <a href="https://itl.ucsf.edu/">Immunogenetics & Transplantation Lab</a> </li> <li class="menu-item"> <a href="https://kornblithlab.ucsf.edu/">Kornblith Lab</a> </li> <li class="menu-item"> <a href="https://kratzlab.ucsf.edu/">Kratz Lab</a> </li> <li class="menu-item"> <a href="https://lobularbreastcancer.ucsf.edu/">Lobular Breast Cancer Research Program</a> </li> <li class="menu-item"> <a href="https://mackenzielab.ucsf.edu/">MacKenzie Lab</a> </li> <li class="menu-item"> <a href="https://nijagallab.ucsf.edu/">Nijagal Lab</a> </li> <li class="menu-item"> <a href="https://pedsurglab.ucsf.edu/">Pediatric Surgery Lab</a> </li> <li class="menu-item"> <a href="https://pomerantzlab.ucsf.edu/">Pomerantz Lab</a> </li> <li class="menu-item"> <a href="https://wraparound.ucsf.edu/">San Francisco Wraparound Project</a> </li> <li class="menu-item"> <a href="https://sarwallab.ucsf.edu/">Sarwal Lab</a> </li> <li class="menu-item"> <a href="https://surgicalinnovations.ucsf.edu/">Surgical Innovations</a> 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3.12031 1 3.12031" stroke="#CACED2" stroke-miterlimit="10"/> </svg> </div> </div> <div class="content-carousel-card-content"> <div class="heading"> <div class="field field--name-field-heading field--type-string field--label-hidden field__item">Investigating Mechanisms to Develop New Diagnostic and Therapeutic Strategies</div> </div> <div class="body"> <div class="clearfix text-formatted field field--name-field-body field--type-text field--label-hidden field__item">Kornblith Lab</div> </div> <div class="link"> <a href="/kornblith-lab-research" aria-label="">Our Research</a> </div> </div> </div> </div> </div> </div> </div> <div class="field__item"> <div > <div class="columns text-vert-align--top columns--layout-sidebar-left paragraph paragraph--type--kan-columns paragraph--view-mode--default no-decor"> <div class="field field--name-field-heading field--type-string field--label-hidden field__item"> Improving Outcomes for Critically Injured Trauma Patients through Basic and Translational Science </div> <div class="columns__wrap"> <div class="columns__item-list"> <div class="columns__item columns-col1"> <div > <div class="text-block paragraph paragraph--type--kan-text paragraph--view-mode--default"> <div class="text-block__text"> <a href="/node/9171"> <article class="media media--type-image media--view-mode-rounded-overlay" aria-label="Image about Lucy Zumwinkle Kornblith, MD, FACS "> <div class="corner-detail mobile"> <svg version="1.1" id="Layer_1" x="0px" y="0px" width="50px" height="50px" viewBox="0 0 50 50" style="enable-background:new 0 0 50 50;" xml:space="preserve" xmlns:xlink="http://www.w3.org/1999/xlink"> <style type="text/css"> .st0{fill:none;stroke:#FEB80A;stroke-width:5;stroke-miterlimit:10;} </style> <polyline class="st0" points="2.5,50 2.5,2.5 50,2.5 " /> </svg> </div> <div class="corner-detail desktop"> <svg version="1.1" id="Layer_1" x="0px" y="0px" width="100px" height="100px" viewBox="0 0 100 100" style="enable-background:new 0 0 100 100;" xml:space="preserve" xmlns:xlink="http://www.w3.org/1999/xlink"> <style type="text/css"> .st0{fill:none;stroke:#FEB80A;stroke-width:5;stroke-miterlimit:10;} </style> <polyline class="st0" points="2.5,100 2.5,2.5 100,2.5 " /> </svg> </div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/rounded_overlay/public/2023-08/Kornblith-headshot-homepage354x210.jpg.webp?itok=L7K74qlO" width="354" height="210" alt=" Lucy Zumwinkle Kornblith, MD, FACS " class="image-style-rounded-overlay"> </div> </article> </a><h3>Lucy Zumwinkle Kornblith, MD, FACS</h3><p style="font-size:1rem;">Associate Professor of Surgery <br>Division of General Surgery <br>Trauma and Surgical Critical Care <br>Zuckerberg San Francisco General Hospital <br>The Director of Gender Equity <br>Co-chair, Muriel Steele Society</p><p> </p> </div> </div> </div></div> <div class="columns__item columns-col2"> <div > <div class="text-block paragraph paragraph--type--kan-text paragraph--view-mode--default"> <div class="text-block__text"> <p>Traumatic injury is a leading cause of mortality and morbidity worldwide. Despite many advances in care, death from hemorrhage remains a primary cause of early, preventable deaths from injury. Disordered coagulation in the setting of injury and shock, termed trauma-induced coagulopathy, is seen in 25% of these hemorrhaging patients.</p><p>Multiple mediators and mechanisms have been targeted to improve outcomes from trauma-induced coagulopathy, but the cellular contributors remain understudied. These cellular contributors include platelets and endothelium, and are the focus of the basic and translational trauma research laboratory at Zuckerberg San Francisco General Hospital led by Lucy Kornblith, M.D.</p><p>Dr. Kornblith is a surgeon scientist focused on elucidating the mechanisms and mediators of trauma-induced coagulopathy to develop new diagnostic and therapeutic strategies to improve the care of critically injured patients. She has expertise in the study of post-injury platelet biology, functional laboratory measures of coagulation, and in nuances of biospecimen collection in large cohorts of severely injured patients.</p><p><a class="btn-outline-editor" href="/node/1776" data-entity-type="node" data-entity-uuid="f80933ab-f966-4382-80cd-102ad7d070ea" data-entity-substitution="canonical">Read more</a></p> </div> </div> </div></div> </div> </div> </div> </div> </div> <div class="field__item"> <div > <div class="paragraph paragraph--type--faculty-grid paragraph--view-mode--default"> <div class="faculty-text"> <div class="field field--name-field-title field--type-text field--label-hidden field__item"><h2>Meet the Team</h2></div> <div class="clearfix text-formatted field field--name-field-paragraph field--type-text-long field--label-hidden field__item"><p>The members of UCSF Kornblith Lab team encompass a rich blend of expertise and backgrounds, each member bringing a unique perspective to the table, fostering an environment of dynamic exploration and innovative discovery.</p></div> </div> <div class="faculty-images"> <div class="main-image"> <div class="yellow-round-border"> <svg viewBox="0 0 382 382" fill="none" xmlns="http://www.w3.org/2000/svg"> <path class="border-stroke" d="M379 191C379 294.83 294.83 379 191 379M3 191C3 87.1705 87.1705 3 191 3" stroke="#FEB80A" stroke-width="5"/> </svg> </div> <div class="field field--name-field-main-image field--type-entity-reference field--label-visually_hidden"> <div class="field__label visually-hidden">Main Image</div> <div class="field__item"> <article class="media media--type-image media--view-mode-faculty-grid-images" aria-label="Image about Kornblith Faculty Grid"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="eager" srcset="/sites/default/files/styles/faculty_grid_focal_point/public/2023-09/KornblithFacultyGrid-Main.jpg.webp?itok=8yGvg4kN 1600w" sizes="(min-width: 1290px) 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identify therapeutic targets and optimize treatments to improve the care of injured patients. </p><p style="margin-bottom:-10px;">We do this through:</p><ol><li style="font-size:1.25rem;margin-bottom:5px;">Translational research to identify novel biology of blood system failure through the lens of platelets</li><li style="font-size:1.25rem;margin-bottom:5px;">Large observational studies to identify predictors of bad outcomes after injury</li><li style="font-size:1.25rem;margin-bottom:5px;">Clinical trials investigating therapeutics and resuscitation strategies for injured patients</li></ol><p><a class="btn-outline-editor" href="/node/1776" data-entity-type="node" data-entity-uuid="8da0a129-fcfb-4d9a-b2cf-cc4604929f97" data-entity-substitution="canonical">Learn More</a></p> </div> </div> </div></div> </div> </div> </div> </div> </div> <div class="field__item"> <div > <div class="columns text-vert-align--top columns--layout-column-wider-left paragraph paragraph--type--kan-columns 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srcset="/sites/default/files/styles/news_featured/public/2024-10/lucykornblith-honored-ninersgame.webp?h=a6bd6dc9&itok=2_bXaIum 1308w" sizes="(min-width: 1290px) 81.75rem, (min-width: 768px) 100vw, (min-width: 560px) 100vw" width="1308" height="935" src="/sites/default/files/styles/news_featured/public/2024-10/lucykornblith-honored-ninersgame.webp?h=a6bd6dc9&itok=2_bXaIum" alt="Dr. Kornblith honored at niners game" /> </div> </article> </div> </div> <div class="featured-news-text-wrapper"> <p class="content-title"> <div class="ext__link field field--name-title field--type-string field--label-hidden field__item" target="_blank">Dr. Lucy Kornblith honored at San Francisco 49ers game</div> </p> <svg class="yellow-arrow" width="6" height="8" viewBox="0 0 6 8" fill="none" xmlns="http://www.w3.org/2000/svg"> <path d="M6 4L-3.26266e-07 7.4641L-2.34249e-08 0.535898L6 4Z" fill="#FEB80A"/> </svg> <a class="featured-story-link" href="/news/dr-lucy-kornblith-honored-san-francisco-49ers-game" rel="bookmark">Read full story</a> </div> </div> </article> </div> </div> </div> </div> </div> </div> </div> </div></div> <div class="columns__item columns-col2"> <div class="paragraph paragraph--type--kan-block paragraph--view-mode--default"> <div class="field field--name-kan-field-block field--type-block-field field--label-hidden field__item"><div id="block-twitterblock" class="block block-twitter-block"> <a href="https://twitter.com/lucykornblith" class="twitter-timeline" data-height="600" lang="en" data-tweet-limit="2" aria-live="polite">Tweets by @lucykornblith</a> </div> </div> </div> </div> </div> </div> <div class="field field--name-field-link field--type-link field--label-hidden field__item"><a href="/news">View All News & Events</a></div> </div> </div> </div> <div class="field__item"> <div > <div class="quote__full-width"> <div class="quote-content"> <div class="field field--name-field-quote-text field--type-string-long field--label-hidden field__item"><q>The smallest cells can give us the biggest answers</q></div> <div class="name-proc-wrapper"> <a href="/bio/lucy-kornblith-md-facs" class="quote-credit-link" aria-label="The smallest cells can give us the biggest answers"> <span class="field field--name-field-quote-credit field--type-string field--label-hidden field__item">Lucy Zumwinkle Kornblith, MD, FACS</span> </a> </div> </div> </div> </div></div> <div class="field__item"> <div > <div class="columns columns--layout-equal paragraph paragraph--type--kan-columns paragraph--view-mode--default"> <div class="field field--name-field-heading field--type-string field--label-hidden field__item">Recent Publications</div> <div class="columns__wrap"> <div class="columns__item-list"> <div class="columns__item columns-col1"> <div > <div class="text-block paragraph paragraph--type--kan-text paragraph--view-mode--default"> <div class="text-block__text"> <article class="media media--type-image media--view-mode-rounded-overlay" aria-label="Image about kornblith-publications-hp-image"> <div class="corner-detail mobile"> <svg version="1.1" id="Layer_1" x="0px" y="0px" width="50px" height="50px" viewBox="0 0 50 50" style="enable-background:new 0 0 50 50;" xml:space="preserve" xmlns:xlink="http://www.w3.org/1999/xlink"> <style type="text/css"> .st0{fill:none;stroke:#FEB80A;stroke-width:5;stroke-miterlimit:10;} </style> <polyline class="st0" points="2.5,50 2.5,2.5 50,2.5 " /> </svg> </div> <div class="corner-detail desktop"> <svg version="1.1" id="Layer_1" x="0px" y="0px" width="100px" height="100px" viewBox="0 0 100 100" style="enable-background:new 0 0 100 100;" xml:space="preserve" xmlns:xlink="http://www.w3.org/1999/xlink"> <style type="text/css"> .st0{fill:none;stroke:#FEB80A;stroke-width:5;stroke-miterlimit:10;} </style> <polyline class="st0" points="2.5,100 2.5,2.5 100,2.5 " /> </svg> </div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/rounded_overlay/public/2023-09/kornblith-publications-hp-image.jpg.webp?itok=g1CVcjmF" width="1746" height="1162" alt="kornblith-publications-hp-image" class="image-style-rounded-overlay"> </div> </article> </div> </div> </div></div> <div class="columns__item columns-col2"> <div > <div class="text-block paragraph paragraph--type--kan-text paragraph--view-mode--default"> <div class="text-block__text"> <div style="font-size:1rem;"><p>Effect of the P-selectin Inhibitor Crizanlizumab on Survival Free of Organ Support in Patients Hospitalized for COVID-19: A Randomized Controlled Trial.   <br><a href="http://www.ncbi.nlm.nih.gov/pubmed/37356038" target="_blank">PubMed AbstractPlus</a> </p><p>Effect of P2Y12 Inhibitors on Organ Support-Free Survival in Critically Ill Patients Hospitalized for COVID-19: A Randomized Clinical Trial.   <br><a href="http://www.ncbi.nlm.nih.gov/pubmed/37227729" target="_blank">PubMed AbstractPlus</a> </p><p>Current Use and Utility of MRCP, ERCP and Pancreatic Duct Stents: A Secondary Analysis from the WTA Multicenter Trials Group on Pancreatic Injuries.   <br><a href="http://www.ncbi.nlm.nih.gov/pubmed/37125949" target="_blank">PubMed AbstractPlus</a> </p><p>γ' fibrinogen levels as a biomarker of COVID-19 respiratory disease severity.   <br><a href="http://www.ncbi.nlm.nih.gov/pubmed/37150704" target="_blank">PubMed AbstractPlus</a> </p></div> </div> </div> </div></div> </div> </div> </div> </div> </div> <div class="field__item"> <div > <div class="columns columns--layout-column-wider-right paragraph paragraph--type--kan-columns paragraph--view-mode--default"> <div class="field field--name-field-heading field--type-string field--label-hidden field__item">Support the Kornblith Lab</div> <div class="columns__wrap"> <div class="columns__item-list"> <div class="columns__item columns-col1"> <div > <div class="text-block paragraph paragraph--type--kan-text paragraph--view-mode--default"> <div class="text-block__text"> <p>However you give – as a former patient, family member or friend, alumnus, or corporate or foundation partner – your gift has profound impact on lives today and on tomorrow’s medicine, pioneered at UCSF.</p><p><a class="btn-outline-editor" href="https://makeagift.ucsf.edu/site/SPageServer?pagename=A1_API_GeneralGivingForm&Primary=Surgery&Other=Research%20of%20Lucy%20Zumwinkle%20Kornblith,%20MD,%20Assistant%20Professor,%20Dept.%20of%20Surgery%20-%20Trauma%20and%20Surgical%20Critical%20Care%20ZSFG" target="_blank">Donate Now</a></p> </div> </div> </div></div> <div class="columns__item columns-col2"> <div > <div class="text-block paragraph paragraph--type--kan-text paragraph--view-mode--default"> <div class="text-block__text"> <article class="media media--type-image media--view-mode-rounded-overlay" aria-label="Image about Kornblith Lab Support"> <div class="corner-detail mobile"> <svg version="1.1" id="Layer_1" x="0px" y="0px" width="50px" height="50px" viewBox="0 0 50 50" 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