UCSF Warren Lab in Surgical Oncology

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width:140px; ;padding-top:4px;'><p>Robert S. Warren, M.D.</p> <p>Professor聽of Surgery,<br /> Surgical Oncology Program</p></div><div class='link_text'><a href='https://surgicaloncologylab.ucsf.edu/about-the-lab.aspx'>Director's Vision 禄</a></div></div><div class='bottomRounded'></div></div> <div id='sg_giftbox'><h2 class='sg_message_title' style='font-weight:700;'> Support the Lab</h2><div class='inner'><div class='make_a_gift_inner_text' style='width:168px'><p>Your gift to the Warren Lab in Surgical Oncology helps scientists discover new treatments and cures for聽metastatic colorectal cancer, neuroendocrine tumors of the pancreas聽and other GI cancers.</p></div><div class='link_text'><a href='https://makeagift.ucsf.edu/site/SPageServer?pagename=A1_API_GeneralGivingForm&Primary=Surgery&Other=Department of Surgery - Surgical Oncology Research Lab'>Make a Gift 禄</a></div></div><div class='bottomRounded'></div></div></div><div style='clear:both;display:none;'>level</div> </div>  <div class='freeform-Box-Bottom'></div> </div> </div> </div> </aside>  <div id="sg_centerContent" >   <div id="sg_contentHeading" class='lab_front_heading'> <h1 class="sg_frontPageH1"> </h1> <div class='lab_content_textarea_top'> <h1><br />Discovering Treatments & Cures Through Innovative Translational Research</h1> <p>The Warren laboratory in surgical oncology is conducting research aimed at identifying lesions that lead to the development and spread of cancer.</p> <p>聽</p> <p>聽</p> <p>.聽</p> </div> </div>   <div id="sg_bottomBoxContainer"> <div class="sg_hp_2col fp-pub-news"> <script language="javascript" type="text/javascript" xmlns:user="urn:my-scripts"> function goSelectYear(which) { var nhref = which.options[which.selectedIndex].value; var resId = document.getElementById("goResearch"); var resValue = resId.options[resId.selectedIndex].value; if (resValue != "" ) window.location.href = "?ysearch=" + nhref + "&rasearch=" + resValue; else window.location.href = "?ysearch=" + nhref; } function goSelectRA(which) { var nhref = which.options[which.selectedIndex].value; var resId = document.getElementById("goYear"); var resValue = resId.options[resId.selectedIndex].value; if (resValue != "" ) window.location.href = "?rasearch=" + nhref + "&ysearch=" + resValue; else window.location.href = "?rasearch=" + nhref; } </script><h2 id="sg_frontPageH2" xmlns:user="urn:my-scripts">Recent Publications</h2><table id="pubList" xmlns:user="urn:my-scripts"><tr><td><div class="fp_labs_pubs_list"><table class='pubs-table Warren-Lab-in-Surgical-Oncology'><tr><td><div class='fp_labs_pubs_authors' style=''><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/19759263' >MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer. </a></div></li></ul></td></tr><tr><td><ul class='fp_labs_pubs_items'><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/19324884' >Tissue transglutaminase regulates matrix metalloproteinase-2 in ovarian cancer by modulating cAMP-response element-binding protein activity. </a></div></li></ul></td></tr><tr><td><ul class='fp_labs_pubs_items'><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/19273709' >Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, fluorouracil, and leucovorin in stage III colon cancer: Cancer and Leukemia Group B Protocol 89803. </a></div></li></ul></td></tr><tr><td><ul class='fp_labs_pubs_items'><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/19276255' >p27Kip1 in stage III colon cancer: implications for outcome following adjuvant chemotherapy in cancer and leukemia group B protocol 89803. </a></div></li></ul></td></tr><tr><td><ul class='fp_labs_pubs_items'><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/18987169' >Homeodomain transcription factor NKX2.2 functions in immature cells to control enteroendocrine differentiation and is expressed in gastrointestinal neuroendocrine tumors. </a></div></li></ul></td></tr><tr><td><ul class='fp_labs_pubs_items'><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/19131967' >Sall2 is a novel p75NTR-interacting protein that links NGF signalling to cell cycle progression and neurite outgrowth. </a></div></li></ul></td></tr><tr><td><ul class='fp_labs_pubs_items'><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/19040996' >Mitogen-inducible gene-6 expression correlates with survival and is an independent predictor of recurrence in BRAF(V600E) positive papillary thyroid cancers. </a></div></li></ul></td></tr><tr><td><ul class='fp_labs_pubs_items'><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/19076363' >The Sall2 transcription factor is a novel p75NTR binding protein that promotes the development and function of neurons. </a></div></li></ul></td></tr><tr><td><ul class='fp_labs_pubs_items'><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/18606683' >Type 1 TNF receptor forms a complex with and uses Jak2 and c-Src to selectively engage signaling pathways that regulate transcription factor activity. </a></div></li></ul></td></tr><tr><td><ul class='fp_labs_pubs_items'><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/18523220' >Association of family history with cancer recurrence and survival among patients with stage III colon cancer. </a></div></li></ul></td></tr><tr><td><ul class='fp_labs_pubs_items'><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/18204431' >Immunostaining for peroxisome proliferator gamma distinguishes dedifferentiated liposarcoma from other retroperitoneal sarcomas. </a></div></li></ul></td></tr></table></div></td></tr><tr><td class="fp_labs_pubs_viewall"><a href="https://surgicaloncologylab.ucsf.edu/publications.aspx">View all Publications 禄</a></td></tr></table> </div> <div class="sg_hp_2col fp-pub-news"> <div id="middle_right_section"> <div id="middle_right_section_title"> <h2> News & Events </h2> </div> <table> <tr> <td> <ul class='news_frontpage_lab'> <li><a href='https://surgicaloncologylab.ucsf.edu/news--events/ucsf-news.aspx?id=92769/Department-of-Surgery-staff-and-faculty-receive-2022-Chancellor-Awards-for-Diversity'>Department of Surgery staff and faculty receive 2022 Chancellor Awards for Diversity</a></li><li><a href='https://surgicaloncologylab.ucsf.edu/news--events/ucsf-news.aspx?id=85038/Drs.-Robert-Warren-and-Carlos-Corvera-Awarded-Pilot-Grant-by-Collaborative-Dedicated-to-Reducing-Health-Disparities-in-Cancer'>Drs. Robert Warren and Carlos Corvera Awarded Pilot Grant by Collaborative Dedicated to Reducing Health Disparities in Cancer</a></li><li><a href='https://www.selectscience.net/SelectScience-TV/Videos/rapid-drug-screening-with-patient-derived-organoids-to-drive-personalized-medicine/?videoID=4903'>Rapid Drug Screening with Patient-Derived Organoids to Drive Personalized Medicine</a></li><li><a href='https://surgicaloncologylab.ucsf.edu/news--events/ucsf-news.aspx?id=34935/CFCF-Awards-New-Research-Grant-to-Dr.-Eric-Nakakura-to-Study-Resistance-to-mTOR-Inhibition-in-Pancreatic-Neuroendocrine-Tumors'>CFCF Awards New Research Grant to Dr. Eric Nakakura to Study Resistance to mTOR Inhibition in Pancreatic Neuroendocrine Tumors</a></li><li><a href='https://surgicaloncologylab.ucsf.edu/news--events/ucsf-news.aspx?id=20446/Serendipitous-Discovery-of-a-Cancer-Starter'>Serendipitous Discovery of a Cancer Starter</a></li> </ul> <div class='news_frontpage_readmore' > <div class='news_frontpage_readmore'> <a href="https://surgicaloncologylab.ucsf.edu/news--events.aspx">Read all news <span class="doublearray">»</span></a> </div> </div> </td> </tr> </table> </div> </div> </div>   <div id="slideout_programs_labs_panel" class='display-none'> <form> <div id="findAProgramLabLocal" xmlns:user="urn:my-scripts"><div class="findAProgramCloseButton"><a href="#">聽</a></div><div class="findAProgramHeader"><div class="findAProgramColumnDiv robby">Division Websites & Programs</div><ul class='findAProgramPopoutUL'><li><a href='https://bariatricsurgery.ucsf.edu/'>Bariatric Surgery</a></li><li><a href='https://breastcaresurgery.ucsf.edu/'>Breast Care Surgery</a></li><li><a href='https://colorectalsurgery.ucsf.edu/'>Colorectal Surgery</a></li><li><a href='https://endocrinesurgery.ucsf.edu/'>Endocrine Surgery</a></li><li><a href='https://gisurgery.ucsf.edu/'>Gastrointestinal Surgery</a></li><li><a href='https://generalsurgery.ucsf.edu/'>General Surgery</a></li><li><a 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