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(PDF) BODE Index Vs FEV1 in predicting outcome and number of exacerbations in COPD Patients | IOSR Journals - Academia.edu
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ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Contributions of the Body Mass Index, Obstruction, Dyspnea and Exercise Capacity or BODE index to Chronic Obstructive Pulmonary Disease","attachmentId":118775507,"attachmentType":"pdf","work_url":"https://www.academia.edu/124575636/Contributions_of_the_Body_Mass_Index_Obstruction_Dyspnea_and_Exercise_Capacity_or_BODE_index_to_Chronic_Obstructive_Pulmonary_Disease","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/124575636/Contributions_of_the_Body_Mass_Index_Obstruction_Dyspnea_and_Exercise_Capacity_or_BODE_index_to_Chronic_Obstructive_Pulmonary_Disease"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="36899557" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/36899557/BODE_Index_Vs_FEV1_In_Predicting_Outcome_And_Number_Of_Exacerbations_In_Stable_COPD_Patients">BODE Index Vs FEV1 In Predicting Outcome And Number Of Exacerbations In Stable COPD Patients</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="65581038" href="https://independent.academia.edu/IOSRJDMS">IOSR JDMS</a></div><p class="ds-related-work--abstract ds2-5-body-sm">The mechanisms underlying COPD exacerbations are poorly understood, and it is a high priority to identify factors that help in predicting their occurrence. Aim and Objectives: The present study was conducted to assess BODE index and GOLD severity staging (based on FEV1) in stable COPD patients, and to assess the utility of BODE index and GOLD severity staging in predicting acute exacerbations and their outcomes in the following one year. It is a hospital based prospective observational study done from Results:100 stable COPD patients were enrolled and were followed up for a period of one year or until their death whichever was earlier. 6 patients were lost to follow-up. Out of 94 patients; 23.40% had a BODE index of 0-2, 28.72% had a BODE index of 3-4, 20.21% had a BODE index of 5-6 and 27.67% had a BODE index of 7-10. Out of the 94 patients, 12.76%, 20.21%, 37.23% and 29.80% were categorized into GOLD stage 1, 2, 3 and 4 respectively. 38.29% of patients experienced at least one exacerbation, out of which, 5.31% of were managed with OP-based treatment. The remaining 32.97% of patients were hospitalized, of which, 12.76% succumbed to death. BODE index seems to be a better predictor of exacerbations (AUC=0.951) than FEV1 (AUC=0.794), with higher specificity rate. BODE index predicts OP based management of exacerbations better than FEV1 (AUC-0.916 vs 0.771). BODE index was also found to be a better predictor of hospitalization rates when compared to FEV1 (AUC—0.916 vs 0.771). BODE index was found to be a significant predictor of mortality with a AUC of 0.884 (p<0.0001) when compared to FEV1 (p=0.1379). Conclusion: BODE index and FEV1 were predictors of number of exacerbations, OP-based management and hospitalizations, but BODE index was found to be a better predictor than FEV1. 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