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class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Arcitumomab" title="Arcitumomab – German" lang="de" hreflang="de" data-title="Arcitumomab" data-language-autonym="Deutsch" data-language-local-name="German" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Arcitumomab" title="Arcitumomab – Italian" lang="it" hreflang="it" data-title="Arcitumomab" data-language-autonym="Italiano" data-language-local-name="Italian" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Tehnecijum_(99mTc)_arcitumomab" title="Tehnecijum (99mTc) arcitumomab – Serbian" lang="sr" hreflang="sr" data-title="Tehnecijum (99mTc) arcitumomab" data-language-autonym="Српски / srpski" data-language-local-name="Serbian" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Tehnecijum_(99mTc)_arcitumomab" title="Tehnecijum (99mTc) arcitumomab – Serbo-Croatian" lang="sh" hreflang="sh" data-title="Tehnecijum (99mTc) arcitumomab" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="Serbo-Croatian" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Technetium_(99mTc)_arcitumomab" title="Technetium (99mTc) arcitumomab – Vietnamese" lang="vi" hreflang="vi" data-title="Technetium (99mTc) arcitumomab" data-language-autonym="Tiếng Việt" data-language-local-name="Vietnamese" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span 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<div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="en" dir="ltr"><div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Pharmaceutical drug</div> <style data-mw-deduplicate="TemplateStyles:r1257001546">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox" style="border-spacing:2px;"><caption class="infobox-title"><span title="International nonproprietary name (INN): Technetium (<sup>99m</sup>Tc) arcitumomab">Technetium (<sup>99m</sup>Tc) arcitumomab</span></caption><tbody><tr><th colspan="2" class="infobox-header" style="background:#ddd"><a href="/wiki/Monoclonal_antibody" title="Monoclonal antibody">Monoclonal antibody</a></th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/File:Engineered_monoclonal_antibodies.svg" title="File:Engineered monoclonal antibodies.svg">Type</a></th><td class="infobox-data"><a href="/wiki/Fab%27_fragment" class="mw-redirect" title="Fab' fragment">Fab' fragment</a></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Monoclonal_antibody#Production" title="Monoclonal antibody">Source</a></th><td class="infobox-data"><a href="/wiki/Mouse" title="Mouse">Mouse</a></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Antigen" title="Antigen">Target</a></th><td class="infobox-data"><a href="/wiki/Carcinoembryonic_antigen" title="Carcinoembryonic antigen">CEA</a></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd">Clinical data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Route_of_administration" title="Route of administration">Routes of<br />administration</a></th><td class="infobox-data"><a href="/wiki/Intravenous" class="mw-redirect" title="Intravenous">Intravenous</a></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Anatomical_Therapeutic_Chemical_Classification_System" title="Anatomical Therapeutic Chemical Classification System">ATC code</a></th><td class="infobox-data"><style data-mw-deduplicate="TemplateStyles:r1126788409">.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}</style><div class="plainlist"><ul><li><a href="/wiki/ATC_code_V09" title="ATC code V09">V09IA06</a> (<span title="www.whocc.no"><a rel="nofollow" class="external text" href="https://www.whocc.no/atc_ddd_index/?code=V09IA06">WHO</a></span>) </li></ul></div></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd">Legal status</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Regulation_of_therapeutic_goods" title="Regulation of therapeutic goods">Legal status</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"> <ul><li>In general: ℞ (Prescription only)</li></ul></div> </td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd"><a href="/wiki/Pharmacokinetics" title="Pharmacokinetics">Pharmacokinetic</a> data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Bioavailability" title="Bioavailability">Bioavailability</a></th><td class="infobox-data">N/A</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Biological_half-life" title="Biological half-life">Elimination <span class="nowrap">half-life</span></a></th><td class="infobox-data">13 ± 4 hours</td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd">Identifiers</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/CAS_Registry_Number" title="CAS Registry Number">CAS Number</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="commonchemistry.cas.org"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=154361-49-6">154361-49-6</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/DrugBank" title="DrugBank">DrugBank</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="www.drugbank.ca"><a rel="nofollow" class="external text" href="https://www.drugbank.ca/drugs/DB00113">DB00113</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ChemSpider" title="ChemSpider">ChemSpider</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li>none</li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Unique_Ingredient_Identifier" title="Unique Ingredient Identifier">UNII</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="precision.fda.gov"><a rel="nofollow" class="external text" href="https://precision.fda.gov/uniisearch/srs/unii/029JF1SCU8">029JF1SCU8</a></span></li></ul></div></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd">Chemical and physical data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Molar_mass" title="Molar mass">Molar mass</a></th><td class="infobox-data">54 kDa<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (December 2023)">citation needed</span></a></i>]</sup></td></tr><tr><td colspan="2" class="infobox-below"><style data-mw-deduplicate="TemplateStyles:r886047488">.mw-parser-output .nobold{font-weight:normal}</style><span class="nobold">  <span class="reflink plainlinks nourlexpansion"><a class="external text" href="https://en.wikipedia.org/w/index.php?title=Special:ComparePages&rev1=470478168&page2=Technetium+%2899mTc%29+arcitumomab">(verify)</a></span></span></td></tr></tbody></table> <p><b>Technetium (<sup>99m</sup>Tc) arcitumomab</b> was a drug used for the diagnostic imaging of <a href="/wiki/Colorectal_cancer" title="Colorectal cancer">colorectal cancers</a>, marketed by <a href="/wiki/Immunomedics" title="Immunomedics">Immunomedics</a>.<sup id="cite_ref-SPC_1-0" class="reference"><a href="#cite_note-SPC-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> It consisted of the <a href="/wiki/Fab%27_fragment" class="mw-redirect" title="Fab' fragment">Fab' fragment</a> of a <a href="/wiki/Monoclonal_antibody" title="Monoclonal antibody">monoclonal antibody</a> (arcitumomab, trade name <b>CEA-Scan</b>) and a <a href="/wiki/Radionuclide" title="Radionuclide">radionuclide</a>, <a href="/wiki/Technetium-99m" title="Technetium-99m">technetium-99m</a>. </p><p>CEA-Scan was approved by the European Medicine Association (EMA) on October of 1996 for imaging in the case of metastases and/or recurrence in patients that were suffering from colon or rectum cancer. Under the same decision, it was also approved to be used in patients that were suspected to have colon or rectal carcinoma recurrence and/or metastasis in association with rising blood CEA-levels. <sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Chemistry">Chemistry</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Technetium_(99mTc)_arcitumomab&action=edit&section=1" title="Edit section: Chemistry"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Technetium (<sup>99m</sup>Tc) arcitumomab is an <a href="/wiki/Immunoconjugate" title="Immunoconjugate">immunoconjugate</a>. Arcitumomab is a Fab' fragment of IMMU-4, a <a href="/wiki/Murine" class="mw-redirect" title="Murine">murine</a> <a href="/wiki/IgG1" class="mw-redirect" title="IgG1">IgG1</a> monoclonal antibody extracted from the <a href="/wiki/Ascites" title="Ascites">ascites</a> of mice. The enzyme <a href="/wiki/Pepsin" title="Pepsin">pepsin</a> cleaves the F(ab')<sub>2</sub> fragment off the antibody. From this, the Fab' fragment is prepared by mild <a href="/wiki/Reduction_(chemistry)" class="mw-redirect" title="Reduction (chemistry)">reduction</a>. </p><p>Before application, arcitumomab is reconstituted with a solution of the radioactive agent sodium <a href="/wiki/Pertechnetate" title="Pertechnetate">pertechnetate</a> (<sup>99m</sup>Tc) from a <a href="/wiki/Technetium_generator" class="mw-redirect" title="Technetium generator">technetium generator</a>.<sup id="cite_ref-SPC_1-1" class="reference"><a href="#cite_note-SPC-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Mechanism_of_action">Mechanism of action</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Technetium_(99mTc)_arcitumomab&action=edit&section=2" title="Edit section: Mechanism of action"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Arcitumomab recognizes <a href="/wiki/Carcinoembryonic_antigen" title="Carcinoembryonic antigen">carcinoembryonic antigen</a> (CEA), an antigen over-<a href="/wiki/Expression_(genetics)" class="mw-redirect" title="Expression (genetics)">expressed</a> in 95% of colorectal cancers.<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> Consequently, the antibody accumulates in such tumours together with the radioisotope, which emits <a href="/wiki/Photon" title="Photon">photons</a>. Via <a href="/wiki/Single_photon_emission_computed_tomography" class="mw-redirect" title="Single photon emission computed tomography">single photon emission computed tomography</a> (SPECT), high-resolution images showing localisation, <a href="/wiki/Remission_(medicine)" title="Remission (medicine)">remission</a> or progression, and <a href="/wiki/Metastases" class="mw-redirect" title="Metastases">metastases</a> of the tumour can be obtained.<sup id="cite_ref-SPC_1-2" class="reference"><a href="#cite_note-SPC-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Contraindications">Contraindications</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Technetium_(99mTc)_arcitumomab&action=edit&section=3" title="Edit section: Contraindications"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Technetium (<sup>99m</sup>Tc) arcitumomab is <a href="/wiki/Contraindicated" class="mw-redirect" title="Contraindicated">contraindicated</a> for patients with known allergies or hypersensitivity to mouse proteins, as well as during pregnancy. Women should pause breast feeding for 24 hours after application of the drug.<sup id="cite_ref-SPC_1-3" class="reference"><a href="#cite_note-SPC-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Adverse_effects_and_overdose">Adverse effects and overdose</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Technetium_(99mTc)_arcitumomab&action=edit&section=4" title="Edit section: Adverse effects and overdose"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Only mild and transient side effects have been observed, mostly immunological reactions like <a href="/wiki/Eosinophilia" title="Eosinophilia">eosinophilia</a>, itching and fever. Some patients develop <a href="/wiki/Human_anti-mouse_antibody" title="Human anti-mouse antibody">human anti-mouse antibodies</a>, so there is the theoretical possibility of <a href="/wiki/Anaphylactic_reactions" class="mw-redirect" title="Anaphylactic reactions">anaphylactic reactions</a>. High doses of IMMU-4 (up to 20-fold diagnostic arcitumomab dose) have not led to any serious events. One patient has been reported to develop a <a href="/wiki/Grand_mal" class="mw-redirect" title="Grand mal">grand mal</a> after application.<sup id="cite_ref-SPC_1-4" class="reference"><a href="#cite_note-SPC-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </p><p>Radioactivity can lead to <a href="/wiki/Radiation_poisoning" class="mw-redirect" title="Radiation poisoning">radiation poisoning</a>. Since the dose of an arcitumomab application is about 10 m<a href="/wiki/Sievert" title="Sievert">Sv</a>,<sup id="cite_ref-SPC_1-5" class="reference"><a href="#cite_note-SPC-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> such an overdose is unlikely. </p> <div class="mw-heading mw-heading2"><h2 id="Removal_from_market">Removal from market</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Technetium_(99mTc)_arcitumomab&action=edit&section=5" title="Edit section: Removal from market"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>In August 2005, the marketing company Immunodemics voluntarily decided to withdraw the product from the market. </p><p>In September 2005, EMA accepted the decision and CEA-Scan was removed from the market.<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Technetium_(99mTc)_arcitumomab&action=edit&section=6" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-SPC-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-SPC_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-SPC_1-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-SPC_1-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-SPC_1-3"><sup><i><b>d</b></i></sup></a> <a href="#cite_ref-SPC_1-4"><sup><i><b>e</b></i></sup></a> <a href="#cite_ref-SPC_1-5"><sup><i><b>f</b></i></sup></a></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20160313061725/http://cea-scan.com/inserts/epckginst.htm">"CEA-Scan Summary of Product Characteristics"</a>. Immunomedics. Archived from <a rel="nofollow" class="external text" href="http://www.cea-scan.com/inserts/epckginst.htm">the original</a> on 2016-03-13<span class="reference-accessdate">. Retrieved <span class="nowrap">2009-10-28</span></span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=CEA-Scan+Summary+of+Product+Characteristics&rft.pub=Immunomedics&rft_id=http%3A%2F%2Fwww.cea-scan.com%2Finserts%2Fepckginst.htm&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATechnetium+%2899mTc%29+arcitumomab" class="Z3988"></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ema.europa.eu/en/medicines/human/EPAR/cea-scan#more-information-on-cea-scan-1536">"CEA-Scan | European Medicines Agency (EMA)"</a>. <i>www.ema.europa.eu</i>. 2005-11-16<span class="reference-accessdate">. Retrieved <span class="nowrap">2024-09-30</span></span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=www.ema.europa.eu&rft.atitle=CEA-Scan+%7C+European+Medicines+Agency+%28EMA%29&rft.date=2005-11-16&rft_id=https%3A%2F%2Fwww.ema.europa.eu%2Fen%2Fmedicines%2Fhuman%2FEPAR%2Fcea-scan%23more-information-on-cea-scan-1536&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATechnetium+%2899mTc%29+arcitumomab" class="Z3988"></span></span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFGuadagniKantorAloeCarone2001" class="citation journal cs1">Guadagni F, Kantor J, Aloe S, Carone MD, Spila A, D'Alessandro R, et al. 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"Targeting of liver metastases of colorectal cancer with IgG, F(ab')2, and Fab' anti-carcinoembryonic antigen antibodies labeled with 99mTc: the role of metabolism and kinetics". <i>Cancer Research</i>. <b>55</b> (23 Suppl): 5777s–5785s. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/7493346">7493346</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Cancer+Research&rft.atitle=Targeting+of+liver+metastases+of+colorectal+cancer+with+IgG%2C+F%28ab%27%292%2C+and+Fab%27+anti-carcinoembryonic+antigen+antibodies+labeled+with+99mTc%3A+the+role+of+metabolism+and+kinetics&rft.volume=55&rft.issue=23+Suppl&rft.pages=5777s-5785s&rft.date=1995-12&rft_id=info%3Apmid%2F7493346&rft.aulast=Behr&rft.aufirst=T&rft.au=Becker%2C+W&rft.au=Hannappel%2C+E&rft.au=Goldenberg%2C+DM&rft.au=Wolf%2C+F&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATechnetium+%2899mTc%29+arcitumomab" class="Z3988"></span></span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-5">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ema.europa.eu/en/medicines/human/EPAR/cea-scan#more-information-on-cea-scan-1536">"CEA-Scan | European Medicines Agency (EMA)"</a>. <i>www.ema.europa.eu</i>. 2005-11-16<span class="reference-accessdate">. Retrieved <span class="nowrap">2024-09-30</span></span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=www.ema.europa.eu&rft.atitle=CEA-Scan+%7C+European+Medicines+Agency+%28EMA%29&rft.date=2005-11-16&rft_id=https%3A%2F%2Fwww.ema.europa.eu%2Fen%2Fmedicines%2Fhuman%2FEPAR%2Fcea-scan%23more-information-on-cea-scan-1536&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATechnetium+%2899mTc%29+arcitumomab" class="Z3988"></span></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="Further_reading">Further reading</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Technetium_(99mTc)_arcitumomab&action=edit&section=7" title="Edit section: Further reading"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239549316">.mw-parser-output .refbegin{margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}@media screen{.mw-parser-output .refbegin{font-size:90%}}</style><div class="refbegin" style=""> <ul><li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPrimusNewellBlueGoldenberg1983" class="citation journal cs1">Primus FJ, Newell KD, Blue A, Goldenberg DM (February 1983). "Immunological heterogeneity of carcinoembryonic antigen: antigenic determinants on carcinoembryonic antigen distinguished by monoclonal antibodies". <i>Cancer Research</i>. <b>43</b> (2): 686–92. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/6184152">6184152</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Cancer+Research&rft.atitle=Immunological+heterogeneity+of+carcinoembryonic+antigen%3A+antigenic+determinants+on+carcinoembryonic+antigen+distinguished+by+monoclonal+antibodies&rft.volume=43&rft.issue=2&rft.pages=686-92&rft.date=1983-02&rft_id=info%3Apmid%2F6184152&rft.aulast=Primus&rft.aufirst=FJ&rft.au=Newell%2C+KD&rft.au=Blue%2C+A&rft.au=Goldenberg%2C+DM&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATechnetium+%2899mTc%29+arcitumomab" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFHansenJonesSharkeyGrebenau1990" class="citation journal cs1">Hansen HJ, Jones AL, Sharkey RM, Grebenau R, Blazejewski N, Kunz A, et al. (February 1990). "Preclinical evaluation of an "instant" 99mTc-labeling kit for antibody imaging". <i>Cancer Research</i>. <b>50</b> (3 Suppl): 794s–798s. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/2297726">2297726</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Cancer+Research&rft.atitle=Preclinical+evaluation+of+an+%22instant%22+99mTc-labeling+kit+for+antibody+imaging&rft.volume=50&rft.issue=3+Suppl&rft.pages=794s-798s&rft.date=1990-02&rft_id=info%3Apmid%2F2297726&rft.aulast=Hansen&rft.aufirst=HJ&rft.au=Jones%2C+AL&rft.au=Sharkey%2C+RM&rft.au=Grebenau%2C+R&rft.au=Blazejewski%2C+N&rft.au=Kunz%2C+A&rft.au=Buckley%2C+MJ&rft.au=Newman%2C+ES&rft.au=Ostella%2C+F&rft.au=Goldenberg%2C+DM&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATechnetium+%2899mTc%29+arcitumomab" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFHughes1995" class="citation journal cs1">Hughes K (1995). "Use of radioimmunodetection with CEAScan in planning for resection of recurrent colorectal cancer". <i>Proc Amer Soc Clin Oncol</i>. <b>14</b>: 544.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proc+Amer+Soc+Clin+Oncol&rft.atitle=Use+of+radioimmunodetection+with+CEAScan+in+planning+for+resection+of+recurrent+colorectal+cancer&rft.volume=14&rft.pages=544&rft.date=1995&rft.aulast=Hughes&rft.aufirst=K&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATechnetium+%2899mTc%29+arcitumomab" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMoffatPinskyHammershaimbPetrelli1996" class="citation journal cs1">Moffat FL, Pinsky CM, Hammershaimb L, Petrelli NJ, Patt YZ, Whaley FS, Goldenberg DM (August 1996). "Clinical utility of external immunoscintigraphy with the IMMU-4 technetium-99m Fab' antibody fragment in patients undergoing surgery for carcinoma of the colon and rectum: results of a pivotal, phase III trial. The Immunomedics Study Group". <i>Journal of Clinical Oncology</i>. <b>14</b> (8): 2295–305. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1200%2FJCO.1996.14.8.2295">10.1200/JCO.1996.14.8.2295</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/8708720">8708720</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Oncology&rft.atitle=Clinical+utility+of+external+immunoscintigraphy+with+the+IMMU-4+technetium-99m+Fab%27+antibody+fragment+in+patients+undergoing+surgery+for+carcinoma+of+the+colon+and+rectum%3A+results+of+a+pivotal%2C+phase+III+trial.+The+Immunomedics+Study+Group&rft.volume=14&rft.issue=8&rft.pages=2295-305&rft.date=1996-08&rft_id=info%3Adoi%2F10.1200%2FJCO.1996.14.8.2295&rft_id=info%3Apmid%2F8708720&rft.aulast=Moffat&rft.aufirst=FL&rft.au=Pinsky%2C+CM&rft.au=Hammershaimb%2C+L&rft.au=Petrelli%2C+NJ&rft.au=Patt%2C+YZ&rft.au=Whaley%2C+FS&rft.au=Goldenberg%2C+DM&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATechnetium+%2899mTc%29+arcitumomab" class="Z3988"></span></li></ul> </div> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1129693374">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist 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abbr{color:var(--color-base)!important}@media(prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}}@media print{.mw-parser-output .navbar{display:none!important}}</style><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Diagnostic_radiopharmaceuticals" title="Template:Diagnostic radiopharmaceuticals"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Diagnostic_radiopharmaceuticals" title="Template talk:Diagnostic radiopharmaceuticals"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Diagnostic_radiopharmaceuticals" title="Special:EditPage/Template:Diagnostic radiopharmaceuticals"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Diagnostic_radiopharmaceuticals_(V09)" style="font-size:114%;margin:0 4em">Diagnostic <a href="/wiki/Radiopharmacology" title="Radiopharmacology">radiopharmaceuticals</a> (<a href="/wiki/ATC_code_V09" title="ATC code V09">V09</a>)</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Central_nervous_system" title="Central nervous system">Central nervous system</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Technetium-99m" title="Technetium-99m"><sup>99m</sup>Tc</a> (<a href="/wiki/Technetium_(99mTc)_exametazime" title="Technetium (99mTc) exametazime">Exametazime</a>, <a href="/wiki/Technetium_(99mTc)_pentetic_acid" title="Technetium (99mTc) pentetic acid">Pentetic acid</a>)</li> <li><a href="/wiki/Iodine-123" title="Iodine-123"><sup>123</sup>I</a> (<a href="/wiki/Ioflupane_(123I)" title="Ioflupane (123I)">Ioflupane (123I)</a></li> <li><a href="/wiki/Iofetamine_(123I)" title="Iofetamine (123I)">Iofetamine (123I)</a></li> <li><a href="/wiki/Iolopride_(123I)" class="mw-redirect" title="Iolopride (123I)">Iolopride (123I)</a></li> <li><a href="/wiki/Iomazenil_(123I)" class="mw-redirect" title="Iomazenil (123I)">Iomazenil</a>)</li> <li><a href="/wiki/Fluorine-18" title="Fluorine-18"><sup>18</sup>F</a> (<a href="/wiki/Florbetapir_(18F)" title="Florbetapir (18F)">Florbetapir (18F)</a>, <a href="/wiki/Flutemetamol_(18F)" title="Flutemetamol (18F)">Flutemetamol (18F)</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Skeletal_system" class="mw-redirect" title="Skeletal system">Skeletal system</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Technetium-99m" title="Technetium-99m"><sup>99m</sup>Tc</a> (<a href="/wiki/Technetium_(99mTc)_medronic_acid" title="Technetium (99mTc) medronic acid">Medronic acid</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Renal" class="mw-redirect" title="Renal">Renal</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Iodine-123" title="Iodine-123"><sup>123</sup>I</a> (<a href="/wiki/Sodium_iodohippurate" class="mw-redirect" title="Sodium iodohippurate">Sodium iodohippurate</a>)</li> <li><a href="/wiki/Copper-64" title="Copper-64"><sup>64</sup>Cu</a> <ul><li><a href="/wiki/ETS2" title="ETS2">ETS2</a></li></ul></li> <li><a href="/wiki/Technetium-99m" title="Technetium-99m"><sup>99m</sup>Tc</a> (<a href="/wiki/Technetium_(99mTc)_mertiatide" title="Technetium (99mTc) mertiatide">Mertiatide</a>, <a href="/wiki/Technetium_(99mTc)_pentetic_acid" title="Technetium (99mTc) pentetic acid">Pentetic acid</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Gastrointestinal" class="mw-redirect" title="Gastrointestinal">Gastrointestinal</a>/<a href="/wiki/Hepatic" class="mw-redirect" title="Hepatic">Hepatic</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Selenium-75" class="mw-redirect" title="Selenium-75"><sup>75</sup>Se</a> (<a href="/wiki/SeHCAT" title="SeHCAT">SeHCAT</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Respiratory_system" title="Respiratory system">Respiratory system</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Xenon-133" class="mw-redirect" title="Xenon-133"><sup>133</sup>Xe</a></li> <li><a href="/wiki/Krypton-81m" class="mw-redirect" title="Krypton-81m"><sup>81m</sup>Kr</a></li> <li><a href="/wiki/Technetium-99m" title="Technetium-99m"><sup>99m</sup>Tc</a> (<a href="/wiki/Technetium_(99mTc)_albumin_aggregated" title="Technetium (99mTc) albumin aggregated"><sup>99m</sup>Tc-MAA</a>, <a href="/wiki/Technetium_(99mTc)_pentetic_acid" title="Technetium (99mTc) pentetic acid">Pentetic acid</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Circulatory_system" title="Circulatory system">Cardiovascular system</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Technetium-99m" title="Technetium-99m"><sup>99m</sup>Tc</a> (<a href="/wiki/Technetium_(99mTc)_sestamibi" title="Technetium (99mTc) sestamibi">Sestamibi</a></li> <li><a href="/wiki/Technetium_(99mTc)_tetrofosmin" title="Technetium (99mTc) tetrofosmin">Tetrofosmin</a>)</li> <li><a href="/wiki/Indium-111" title="Indium-111"><sup>111</sup>In</a> (<a href="/wiki/Indium_(111In)_imciromab" title="Indium (111In) imciromab">Imciromab</a>)</li> <li><a href="/wiki/Rubidium-82" title="Rubidium-82"><sup>82</sup>Rb</a> (<a href="/wiki/Rubidium-82_chloride" title="Rubidium-82 chloride">Rubidium chloride</a>)</li> <li><a href="/wiki/Iodine-125" title="Iodine-125"><sup>125</sup>I</a> (<a href="/wiki/Iodine_(125I)_human_albumin" title="Iodine (125I) human albumin">Iodinated human albumin</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Inflammation" title="Inflammation">Inflammation</a>/<a href="/wiki/Infection" title="Infection">infection</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Technetium-99m" title="Technetium-99m"><sup>99m</sup>Tc</a> (<a href="/wiki/Technetium_(99mTc)_exametazime" title="Technetium (99mTc) exametazime">Exametazime</a></li> <li><a href="/wiki/Technetium_(99mTc)_sulesomab" title="Technetium (99mTc) sulesomab">Sulesomab</a></li> <li><a href="/wiki/Technetium_(99mTc)_tilmanocept" title="Technetium (99mTc) tilmanocept">Tilmanocept</a>)</li> <li><a href="/wiki/Indium-111" title="Indium-111"><sup>111</sup>In</a></li> <li><a href="/wiki/Gallium-67" class="mw-redirect" title="Gallium-67"><sup>67</sup>Ga</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Tumor" class="mw-redirect" title="Tumor">Tumor</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Technetium-99m" title="Technetium-99m"><sup>99m</sup>Tc</a> <ul><li><a class="mw-selflink selflink">Arcitumomab</a></li> <li><a href="/wiki/Technetium_(99mTc)_votumumab" title="Technetium (99mTc) votumumab">Votumumab</a></li> <li><a href="/wiki/Technetium_(99mTc)_hynic-octreotide" class="mw-redirect" title="Technetium (99mTc) hynic-octreotide">Hynic-octreotide</a></li></ul></li> <li><a href="/wiki/Indium-111" title="Indium-111"><sup>111</sup>In</a> <ul><li><a href="/wiki/Indium_(111In)_capromab_pendetide" title="Indium (111In) capromab pendetide">Capromab pendetide</a></li> <li><a href="/wiki/Indium_(111In)_satumomab_pendetide" title="Indium (111In) satumomab pendetide">Satumomab pendetide</a></li></ul></li> <li><a href="/wiki/Iodine-125" title="Iodine-125"><sup>125</sup>I</a><span class="nowrap"> </span>(<a href="/wiki/Iodine_(125I)_minretumomab" class="mw-redirect" title="Iodine (125I) minretumomab">Minretumomab</a>)</li> <li><a href="/wiki/Iodine-123" title="Iodine-123"><sup>123</sup>I</a><span class="nowrap"> </span>(<a href="/wiki/Iobenguane" title="Iobenguane">Iobenguane (123I)</a>)</li> <li><a href="/wiki/Iodine-131" title="Iodine-131"><sup>131</sup>I</a><span class="nowrap"> </span>(<a href="/wiki/Iobenguane" title="Iobenguane">Iobenguane (131I)</a>)</li> <li><a href="/wiki/Fluorine-18" title="Fluorine-18"><sup>18</sup>F</a> <ul><li><a href="/wiki/Fluciclovine_(18F)" title="Fluciclovine (18F)">Fluciclovine</a></li> <li><a href="/wiki/Fluorodeoxyglucose_(18F)" title="Fluorodeoxyglucose (18F)">Fluorodeoxyglucose</a></li> <li><a href="/wiki/Fluoroethyl-L-tyrosine_(18F)" title="Fluoroethyl-L-tyrosine (18F)">Fluoroethyltyrosine</a></li> <li><a href="/wiki/Sodium_fluoride" title="Sodium fluoride">Sodium fluoride</a></li></ul></li> <li><a href="/wiki/Copper-64" title="Copper-64"><sup>64</sup>Cu</a> <ul><li><a href="/wiki/Copper_(64Cu)_oxodotreotide" title="Copper (64Cu) oxodotreotide">Dotatate</a></li></ul></li> <li><a href="/wiki/Piflufolastat_F-18" title="Piflufolastat F-18">Piflufolastat F-18</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Adrenal_cortex" title="Adrenal cortex">Adrenal cortex</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Iodine-123" title="Iodine-123"><sup>123</sup>I</a></li> <li><a href="/wiki/Iodine-125" title="Iodine-125"><sup>125</sup>I</a> / <a href="/wiki/Iodine-131" title="Iodine-131"><sup>131</sup>I</a> (<a href="/wiki/19-Iodocholesterol" class="mw-redirect" title="19-Iodocholesterol">Iodocholesterol</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Radionuclide" title="Radionuclide">Radionuclides</a><br />(including <a href="/wiki/Radioactive_tracer" title="Radioactive tracer">tracers</a>)</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Positron" title="Positron">positron</a> (<a href="/wiki/PET_radiotracer" title="PET radiotracer">PET</a> <a href="/wiki/List_of_PET_radiotracers" title="List of PET radiotracers">list</a>)</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Carbon-11" class="mw-redirect" title="Carbon-11"><sup>11</sup>C</a> (<a href="/wiki/11C_ME@HAPTHI" title="11C ME@HAPTHI">[<sup>11</sup>C]ME@HAPTHI</a>)</li> <li><a href="/wiki/25B-NBOMe" title="25B-NBOMe">25B-NBOMe</a> (Cimbi-36)</li> <li><a href="/wiki/Acetate" title="Acetate">Acetate</a></li> <li><a href="/wiki/Carbon-11-choline" title="Carbon-11-choline">Choline</a></li> <li><a href="/wiki/Carfentanil" title="Carfentanil">Carfentanil</a></li> <li><a href="/wiki/DASB" title="DASB">DASB</a></li> <li><a href="/wiki/DTBZ" class="mw-redirect" title="DTBZ">DTBZ</a></li> <li><a href="/wiki/Flumazenil" title="Flumazenil">Flumazenil</a></li> <li><a href="/wiki/Methionine" title="Methionine">Methionine</a></li> <li><a href="/wiki/N-Methylspiperone" title="N-Methylspiperone">N-Methylspiperone</a></li> <li><a href="/wiki/Pittsburgh_compound_B" title="Pittsburgh compound B">Pittsburgh compound B</a></li> <li><a href="/wiki/Raclopride" title="Raclopride">Raclopride</a></li> <li><a href="/wiki/Verapamil" title="Verapamil">Verapamil</a>)</li> <li><a href="/wiki/Nitrogen-13" title="Nitrogen-13"><sup>13</sup>N</a> <ul><li><a href="/wiki/Ammonia_(13N)" title="Ammonia (13N)">Ammonia</a></li></ul></li> <li><a href="/wiki/Copper-64" title="Copper-64"><sup>64</sup>Cu</a></li> <li><a href="/wiki/Desmethoxyfallypride" title="Desmethoxyfallypride">Desmethoxyfallypride</a></li> <li><a href="/wiki/Fallypride" title="Fallypride">Fallypride</a></li> <li><a href="/wiki/Florbetaben_(18F)" title="Florbetaben (18F)">Florbetaben (18F)</a></li> <li><a href="/wiki/Florbetapir_(18F)" title="Florbetapir (18F)">Florbetapir (18F)</a></li> <li><a href="/wiki/Flortaucipir_(18F)" title="Flortaucipir (18F)">Flortaucipir (18F)</a></li> <li><a href="/wiki/Flotufolastat_F-18" title="Flotufolastat F-18">Flotufolastat F-18</a></li> <li><a href="/w/index.php?title=Flubatine&action=edit&redlink=1" class="new" title="Flubatine (page does not exist)">Flubatine</a></li> <li><a href="/wiki/Fluciclovine" class="mw-redirect" title="Fluciclovine">Fluciclovine</a></li> <li><a href="/wiki/Fludeoxyglucose_(18F)" class="mw-redirect" title="Fludeoxyglucose (18F)">Fludeoxyglucose (18F)</a> (FDG)-<a href="/wiki/Glucose" title="Glucose">glucose</a> analogue</li> <li><a href="/wiki/Flumazenil" title="Flumazenil">Flumazenil</a></li> <li><a href="/wiki/Fluorine-18" title="Fluorine-18"><sup>18</sup>F</a> (<a href="/wiki/Altanserin" title="Altanserin">Altanserin</a>)</li> <li><a href="/wiki/Fluorocholine" title="Fluorocholine">Fluorocholine</a></li> <li><a href="/w/index.php?title=Fluorodeoxysorbitol&action=edit&redlink=1" class="new" title="Fluorodeoxysorbitol (page does not exist)">Fluorodeoxysorbitol</a> (FDS)</li> <li><a href="/wiki/Fluorodopa" title="Fluorodopa">Fluorodopa</a></li> <li><a href="/wiki/Fluoroestradiol_F-18" title="Fluoroestradiol F-18">Fluoroestradiol F-18</a></li> <li><a href="/wiki/Fluorothymidine_F-18" title="Fluorothymidine F-18">Fluorothymidine F-18</a></li> <li><a href="/wiki/Flurpiridaz_(18F)" title="Flurpiridaz (18F)">Flurpiridaz (18F)</a></li> <li><a href="/w/index.php?title=Fluspidine&action=edit&redlink=1" class="new" title="Fluspidine (page does not exist)">Fluspidine</a></li> <li><a href="/wiki/Flutemetamol" class="mw-redirect" title="Flutemetamol">Flutemetamol</a></li> <li><a href="/wiki/FMISO" title="FMISO">FMISO</a></li> <li><a href="/wiki/Gallium_(68Ga)_gozetotide" title="Gallium (68Ga) gozetotide">Gallium (<sup>68</sup>Ga) gozetotide</a></li> <li><a href="/wiki/Gallium-68" class="mw-redirect" title="Gallium-68"><sup>68</sup>Ga</a></li> <li><a href="/wiki/Mefway" class="mw-redirect" title="Mefway">Mefway</a></li> <li><a href="/wiki/MPPF" title="MPPF">MPPF</a></li> <li><a href="/wiki/N-Methylspiperone" title="N-Methylspiperone">N-Methylspiperone</a></li> <li><a href="/wiki/Nifene" title="Nifene">Nifene</a></li> <li><a href="/wiki/O-(2-fluorethyl)-L-thyrosine" class="mw-redirect" title="O-(2-fluorethyl)-L-thyrosine">FET</a></li> <li><a href="/wiki/Oxygen-15" class="mw-redirect" title="Oxygen-15"><sup>15</sup>O</a> (<a href="/wiki/Water" title="Water">Water</a>)</li> <li><a href="/wiki/Piflufolastat_F-18" title="Piflufolastat F-18">Piflufolastat F-18</a></li> <li><a href="/wiki/Rubidium-82" title="Rubidium-82"><sup>82</sup>Rb</a> (<a href="/wiki/Rubidium-82_chloride" title="Rubidium-82 chloride">Rubidium chloride</a>)</li> <li><a href="/wiki/Setoperone" title="Setoperone">Setoperone</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Gamma_ray" title="Gamma ray">gamma ray</a>/<a href="/wiki/Photon" title="Photon">photon</a> (<a href="/wiki/Single-photon_emission_computed_tomography" title="Single-photon emission computed tomography">SPECT</a>/<a href="/wiki/Scintigraphy" title="Scintigraphy">scintigraphy</a>)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Chromium-51" class="mw-redirect" title="Chromium-51"><sup>51</sup>Cr</a></li> <li><a href="/wiki/Cobalt-57" class="mw-redirect" title="Cobalt-57"><sup>57</sup>Co</a></li> <li><a href="/wiki/Gallium-67" class="mw-redirect" title="Gallium-67"><sup>67</sup>Ga</a></li> <li><a href="/wiki/Indium-111" title="Indium-111"><sup>111</sup>In</a></li> <li><a href="/wiki/Iodine-123" title="Iodine-123"><sup>123</sup>I</a></li> <li><a href="/wiki/Iodine-125" title="Iodine-125"><sup>125</sup>I</a></li> <li><a href="/wiki/Iodine-131" title="Iodine-131"><sup>131</sup>I</a></li> <li><a href="/wiki/Krypton-81m" class="mw-redirect" title="Krypton-81m"><sup>81m</sup>Kr</a></li> <li><a href="/wiki/Samarium-153" class="mw-redirect" title="Samarium-153"><sup>153</sup>Sm</a></li> <li><a href="/wiki/Selenium-75" class="mw-redirect" title="Selenium-75"><sup>75</sup>Se</a></li> <li><a href="/wiki/Technetium-99m" title="Technetium-99m"><sup>99m</sup>Tc</a></li> <li><a href="/wiki/Thallium-201" class="mw-redirect" title="Thallium-201"><sup>201</sup>Tl</a></li> <li><a href="/wiki/Xenon-133" class="mw-redirect" title="Xenon-133"><sup>133</sup>Xe</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><td class="navbox-abovebelow" colspan="2"><div>Isotopes used: <div class="hlist"> <ul><li><a href="/wiki/Carbon-11" class="mw-redirect" title="Carbon-11">carbon-11</a></li> <li><a href="/wiki/Chromium-51" class="mw-redirect" title="Chromium-51">chromium-51</a></li> <li><a href="/wiki/Cobalt-57" class="mw-redirect" title="Cobalt-57">cobalt-57</a></li> <li><a href="/wiki/Copper-64" title="Copper-64">copper-64</a></li> <li><a href="/wiki/Fluorine-18" title="Fluorine-18">fluorine-18</a></li> <li><a href="/wiki/Gallium-67" class="mw-redirect" title="Gallium-67">gallium-67</a></li> <li><a href="/wiki/Gallium-68" class="mw-redirect" title="Gallium-68">gallium-68</a></li> <li><a href="/wiki/Indium-111" title="Indium-111">indium-111</a></li> <li><a href="/wiki/Iodine-123" title="Iodine-123">iodine-123</a></li> <li><a href="/wiki/Iodine-125" title="Iodine-125">iodine-125</a></li> <li><a href="/wiki/Iodine-131" title="Iodine-131">iodine-131</a></li> <li><a href="/wiki/Krypton-81m" class="mw-redirect" title="Krypton-81m">krypton-81m</a></li> <li><a href="/wiki/Nitrogen-13" title="Nitrogen-13">nitrogen-13</a></li> <li><a href="/wiki/Oxygen-15" class="mw-redirect" title="Oxygen-15">oxygen-15</a></li> <li><a href="/wiki/Rubidium-82" title="Rubidium-82">rubidium-82</a></li> <li><a href="/wiki/Samarium-153" class="mw-redirect" title="Samarium-153">samarium-153</a></li> <li><a href="/wiki/Selenium-75" class="mw-redirect" title="Selenium-75">selenium-75</a></li> <li><a href="/wiki/Technetium-99m" title="Technetium-99m">technetium-99m</a></li> <li><a href="/wiki/Thallium-201" class="mw-redirect" title="Thallium-201">thallium-201</a></li> <li><a href="/wiki/Xenon-133" class="mw-redirect" title="Xenon-133">xenon-133</a></li></ul> </div><div class="hlist">See also: <a href="/wiki/ATC_code_V10" title="ATC code V10">Therapeutic radiopharmaceuticals (V10)</a> </div></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"></div><div role="navigation" class="navbox" aria-labelledby="Monoclonal_antibodies_for_tumors" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Monoclonals_for_tumors" title="Template:Monoclonals for tumors"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Monoclonals_for_tumors" title="Template talk:Monoclonals for tumors"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Monoclonals_for_tumors" title="Special:EditPage/Template:Monoclonals for tumors"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Monoclonal_antibodies_for_tumors" style="font-size:114%;margin:0 4em"><a href="/wiki/Monoclonal_antibody" title="Monoclonal antibody">Monoclonal antibodies</a> for tumors</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align: center;"><a href="/wiki/Neoplasm" title="Neoplasm">Tumor</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Human</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Adecatumumab" title="Adecatumumab">Adecatumumab</a><sup>§</sup></li> <li><a href="/wiki/Amivantamab" title="Amivantamab">Amivantamab</a></li> <li><a href="/wiki/Ascrinvacumab" title="Ascrinvacumab">Ascrinvacumab</a><sup>§</sup></li> <li><a href="/wiki/Atezolizumab" title="Atezolizumab">Atezolizumab</a> (<a href="/wiki/Atezolizumab/hyaluronidase" title="Atezolizumab/hyaluronidase">+hyaluronidase</a>)</li> <li><a href="/w/index.php?title=Balstilimab&action=edit&redlink=1" class="new" title="Balstilimab (page does not exist)">Balstilimab</a><sup>†</sup></li> <li><a href="/w/index.php?title=Botensilimab&action=edit&redlink=1" class="new" title="Botensilimab (page does not exist)">Botensilimab</a></li> <li><a href="/wiki/Cixutumumab" title="Cixutumumab">Cixutumumab</a><sup>§</sup></li> <li><a href="/wiki/Conatumumab" title="Conatumumab">Conatumumab</a><sup>§</sup></li> <li><a href="/wiki/Daratumumab" title="Daratumumab">Daratumumab</a></li> <li><a href="/wiki/Drozitumab" title="Drozitumab">Drozitumab</a><sup>§</sup></li> <li><a href="/wiki/Duligotumab" class="mw-redirect" title="Duligotumab">Duligotumab</a><sup>§</sup></li> <li><a href="/wiki/Dusigitumab" title="Dusigitumab">Dusigitumab</a><sup>§</sup></li> <li><a href="/wiki/Enfortumab_vedotin" title="Enfortumab vedotin">Enfortumab vedotin</a></li> <li><a href="/wiki/Enoticumab" title="Enoticumab">Enoticumab</a><sup>§</sup></li> <li><a href="/wiki/Figitumumab" title="Figitumumab">Figitumumab</a><sup>§</sup></li> <li><a href="/wiki/Flanvotumab" title="Flanvotumab">Flanvotumab</a><sup>§</sup></li> <li><a href="/wiki/Ganitumab" title="Ganitumab">Ganitumab</a><sup>†</sup></li> <li><a href="/wiki/Glembatumumab_vedotin" title="Glembatumumab vedotin">Glembatumumab vedotin</a><sup>†</sup></li> <li><a href="/wiki/Intetumumab" title="Intetumumab">Intetumumab</a><sup>§</sup></li> <li><a href="/wiki/Ipilimumab" title="Ipilimumab">Ipilimumab</a></li> <li><a href="/wiki/Iratumumab" title="Iratumumab">Iratumumab</a><sup>§</sup></li> <li><a href="/wiki/Istiratumab" title="Istiratumab">Istiratumab</a></li> <li><a href="/wiki/Icrucumab" title="Icrucumab">Icrucumab</a><sup>§</sup></li> <li><a href="/wiki/Lexatumumab" title="Lexatumumab">Lexatumumab</a><sup>§</sup></li> <li><a href="/wiki/Lucatumumab" title="Lucatumumab">Lucatumumab</a><sup>§</sup></li> <li><a href="/wiki/Mapatumumab" title="Mapatumumab">Mapatumumab</a><sup>§</sup></li> <li><a href="/wiki/Narnatumab" title="Narnatumab">Narnatumab</a><sup>§</sup></li> <li><a href="/wiki/Necitumumab" title="Necitumumab">Necitumumab</a></li> <li><a href="/wiki/Nesvacumab" title="Nesvacumab">Nesvacumab</a><sup>§</sup></li> <li><a href="/wiki/Nivolumab" title="Nivolumab">Nivolumab</a><sup>#</sup></li> <li><a href="/wiki/Ofatumumab" title="Ofatumumab">Ofatumumab</a></li> <li><a href="/wiki/Olaratumab" title="Olaratumab">Olaratumab</a><sup>†</sup></li> <li><a href="/wiki/Panitumumab" title="Panitumumab">Panitumumab</a></li> <li><a href="/wiki/Patritumab" title="Patritumab">Patritumab</a><sup>§</sup></li> <li><a href="/wiki/Pembrolizumab" title="Pembrolizumab">Pembrolizumab</a><sup>#</sup></li> <li><a href="/wiki/Pritumumab" title="Pritumumab">Pritumumab</a><sup>§</sup></li> <li><a href="/wiki/Radretumab" title="Radretumab">Radretumab</a><sup>§</sup></li> <li><a href="/wiki/Ramucirumab" title="Ramucirumab">Ramucirumab</a></li> <li><a href="/wiki/Rilotumumab" title="Rilotumumab">Rilotumumab</a><sup>†</sup></li> <li><a href="/wiki/Robatumumab" title="Robatumumab">Robatumumab</a><sup>§</sup></li> <li><a href="/wiki/Seribantumab" title="Seribantumab">Seribantumab</a><sup>§</sup></li> <li><a href="/wiki/Sugemalimab" title="Sugemalimab">Sugemalimab</a></li> <li><a href="/wiki/Tarextumab" title="Tarextumab">Tarextumab</a><sup>§</sup></li> <li><a href="/wiki/Tisotumab_vedotin" title="Tisotumab vedotin">Tisotumab vedotin</a></li> <li><a href="/wiki/Teprotumumab" title="Teprotumumab">Teprotumumab</a><sup>†</sup></li> <li><a href="/wiki/Tovetumab" title="Tovetumab">Tovetumab</a><sup>§</sup></li> <li><a href="/wiki/Vantictumab" title="Vantictumab">Vantictumab</a><sup>§</sup></li> <li><a href="/wiki/Technetium_(99mTc)_votumumab" title="Technetium (99mTc) votumumab">Votumumab</a><sup>§</sup></li> <li><a href="/wiki/Zalutumumab" title="Zalutumumab">Zalutumumab</a><sup>†</sup></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Mouse</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Abagovomab" title="Abagovomab">Abagovomab</a></li> <li><a href="/wiki/Indium_(111In)_altumomab_pentetate" title="Indium (111In) altumomab pentetate">Altumomab pentetate</a></li> <li><a href="/wiki/Anatumomab_mafenatox" title="Anatumomab mafenatox">Anatumomab mafenatox</a></li> <li><a class="mw-selflink selflink">Arcitumomab</a></li> <li><a href="/wiki/Bectumomab" title="Bectumomab">Bectumomab</a></li> <li><a href="/wiki/Blinatumomab" title="Blinatumomab">Blinatumomab</a></li> <li><a href="/wiki/Indium_(111In)_capromab_pendetide" title="Indium (111In) capromab pendetide">Capromab pendetide</a></li> <li><a href="/wiki/Detumomab" title="Detumomab">Detumomab</a></li> <li><a href="/wiki/Edrecolomab" title="Edrecolomab">Edrecolomab</a></li> <li><a href="/wiki/Ibritumomab_tiuxetan" title="Ibritumomab tiuxetan">Ibritumomab tiuxetan</a></li> <li><a href="/wiki/Indium_(111In)_igovomab" title="Indium (111In) igovomab">Igovomab</a></li> <li><a href="/wiki/Lilotomab" title="Lilotomab">Lilotomab</a></li> <li><a href="/wiki/Minretumomab" title="Minretumomab">Minretumomab</a></li> <li><a href="/wiki/Mitumomab" title="Mitumomab">Mitumomab</a></li> <li><a href="/wiki/Nacolomab_tafenatox" title="Nacolomab tafenatox">Nacolomab tafenatox</a></li> <li><a href="/wiki/Moxetumomab_pasudotox" title="Moxetumomab pasudotox">Moxetumomab pasudotox</a></li> <li><a href="/wiki/Naptumomab_estafenatox" title="Naptumomab estafenatox">Naptumomab estafenatox</a></li> <li><a href="/wiki/Oregovomab" title="Oregovomab">Oregovomab</a></li> <li><a href="/wiki/Pemtumomab" title="Pemtumomab">Pemtumomab</a><sup>†</sup></li> <li><a href="/wiki/Racotumomab" title="Racotumomab">Racotumomab</a></li> <li><a href="/wiki/Indium_(111In)_satumomab_pendetide" title="Indium (111In) satumomab pendetide">Satumomab pendetide</a></li> <li><a href="/wiki/Solitomab" title="Solitomab">Solitomab</a></li> <li><a href="/wiki/Taplitumomab_paptox" title="Taplitumomab paptox">Taplitumomab paptox</a></li> <li><a href="/wiki/Technetium_(99mTc)_nofetumomab_merpentan" title="Technetium (99mTc) nofetumomab merpentan">Nofetumomab merpentan</a></li> <li><a href="/wiki/Technetium_(99mTc)_pintumomab" title="Technetium (99mTc) pintumomab">Pintumomab</a></li> <li><a href="/wiki/Tenatumomab" title="Tenatumomab">Tenatumomab</a></li> <li><a href="/wiki/Tositumomab" title="Tositumomab">Tositumomab</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Chimeric_antibody" class="mw-redirect" title="Chimeric antibody">Chimeric</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Amatuximab" title="Amatuximab">Amatuximab</a><sup>§</sup></li> <li><a href="/wiki/Bavituximab" title="Bavituximab">Bavituximab</a><sup>§</sup></li> <li><a href="/wiki/Brentuximab_vedotin" title="Brentuximab vedotin">Brentuximab vedotin</a></li> <li><a href="/wiki/Carotuximab" title="Carotuximab">Carotuximab</a><sup>†</sup></li> <li><a href="/wiki/Cetuximab" title="Cetuximab">Cetuximab</a></li> <li><a href="/wiki/Iodine_(131_I)_derlotuximab_biotin" title="Iodine (131 I) derlotuximab biotin">Derlotuximab biotin</a><sup>§</sup></li> <li><a href="/wiki/Dinutuximab" title="Dinutuximab">Dinutuximab</a></li> <li><a href="/wiki/Ecromeximab" title="Ecromeximab">Ecromeximab</a><sup>§</sup></li> <li><a href="/wiki/Ensituximab" title="Ensituximab">Ensituximab</a><sup>§</sup></li> <li><a href="/wiki/Futuximab" title="Futuximab">Futuximab</a><sup>§</sup></li> <li><a href="/wiki/Girentuximab" title="Girentuximab">Girentuximab</a><sup>†</sup></li> <li><a href="/wiki/Indatuximab_ravtansine" title="Indatuximab ravtansine">Indatuximab ravtansine</a><sup>§</sup></li> <li><a href="/wiki/Isatuximab" title="Isatuximab">Isatuximab</a></li> <li><a href="/wiki/Loncastuximab_tesirine" title="Loncastuximab tesirine">Loncastuximab tesirine</a></li> <li><a href="/wiki/Margetuximab" title="Margetuximab">Margetuximab</a></li> <li><a href="/wiki/Mirvetuximab_soravtansine" title="Mirvetuximab soravtansine">Mirvetuximab soravtansine</a></li> <li><a href="/wiki/Rituximab" title="Rituximab">Rituximab</a><sup>#</sup></li> <li><a href="/wiki/Siltuximab" title="Siltuximab">Siltuximab</a></li> <li><a href="/wiki/Ublituximab" title="Ublituximab">Ublituximab</a></li> <li><a href="/wiki/Zolbetuximab" title="Zolbetuximab">Zolbetuximab</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Humanized_antibody" title="Humanized antibody">Humanized</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Abituzumab" title="Abituzumab">Abituzumab</a><sup>§</sup></li> <li><a href="/wiki/Alemtuzumab" title="Alemtuzumab">Alemtuzumab</a></li> <li><a href="/wiki/Axatilimab" title="Axatilimab">Axatilimab</a></li> <li><a href="/wiki/Belantamab_mafodotin" title="Belantamab mafodotin">Belantamab mafodotin</a></li> <li><a href="/wiki/Bevacizumab" title="Bevacizumab">Bevacizumab</a></li> <li><a href="/wiki/Bivatuzumab_mertansine" title="Bivatuzumab mertansine">Bivatuzumab mertansine</a><sup>§</sup></li> <li><a href="/wiki/Brontictuzumab" title="Brontictuzumab">Brontictuzumab</a><sup>§</sup></li> <li><a href="/wiki/Cantuzumab_mertansine" title="Cantuzumab mertansine">Cantuzumab mertansine</a><sup>§</sup></li> <li><a href="/wiki/Cantuzumab_ravtansine" title="Cantuzumab ravtansine">Cantuzumab ravtansine</a><sup>§</sup></li> <li><a href="/wiki/Cirmtuzumab" title="Cirmtuzumab">Cirmtuzumab</a></li> <li><a href="/wiki/Citatuzumab_bogatox" title="Citatuzumab bogatox">Citatuzumab bogatox</a><sup>§</sup></li> <li><a href="/wiki/Yttrium_(90Y)_clivatuzumab_tetraxetan" title="Yttrium (90Y) clivatuzumab tetraxetan">Clivatuzumab tetraxetan</a></li> <li><a href="/wiki/Cofetuzumab_pelidotin" title="Cofetuzumab pelidotin">Cofetuzumab pelidotin</a></li> <li><a href="/wiki/Dacetuzumab" title="Dacetuzumab">Dacetuzumab</a><sup>§</sup></li> <li><a href="/wiki/Demcizumab" title="Demcizumab">Demcizumab</a><sup>§</sup></li> <li><a href="/wiki/Dalotuzumab" title="Dalotuzumab">Dalotuzumab</a><sup>§</sup></li> <li><a href="/wiki/Denintuzumab_mafodotin" title="Denintuzumab mafodotin">Denintuzumab mafodotin</a><sup>§</sup></li> <li><a href="/wiki/Elotuzumab" title="Elotuzumab">Elotuzumab</a></li> <li><a href="/wiki/Emactuzumab" title="Emactuzumab">Emactuzumab</a></li> <li><a href="/wiki/Emibetuzumab" title="Emibetuzumab">Emibetuzumab</a><sup>§</sup></li> <li><a href="/wiki/Enoblituzumab" title="Enoblituzumab">Enoblituzumab</a><sup>§</sup></li> <li><a href="/wiki/Epcoritamab" title="Epcoritamab">Epcoritamab</a></li> <li><a href="/wiki/Etaracizumab" title="Etaracizumab">Etaracizumab</a><sup>§</sup></li> <li><a href="/wiki/Farletuzumab" title="Farletuzumab">Farletuzumab</a><sup>§</sup></li> <li><a href="/wiki/Ficlatuzumab" title="Ficlatuzumab">Ficlatuzumab</a><sup>§</sup></li> <li><a href="/wiki/Flotetuzumab" title="Flotetuzumab">Flotetuzumab</a><sup>§</sup></li> <li><a href="/wiki/Gemtuzumab_ozogamicin" title="Gemtuzumab ozogamicin">Gemtuzumab ozogamicin</a></li> <li><a href="/wiki/Glofitamab" title="Glofitamab">Glofitamab</a></li> <li><a href="/wiki/Imgatuzumab" title="Imgatuzumab">Imgatuzumab</a><sup>§</sup></li> <li><a href="/wiki/Inotuzumab_ozogamicin" title="Inotuzumab ozogamicin">Inotuzumab ozogamicin</a></li> <li><a href="/wiki/Labetuzumab" title="Labetuzumab">Labetuzumab</a><sup>§</sup></li> <li><a href="/wiki/Lifastuzumab_vedotin" title="Lifastuzumab vedotin">Lifastuzumab vedotin</a><sup>§</sup></li> <li><a href="/wiki/Lintuzumab" title="Lintuzumab">Lintuzumab</a><sup>§</sup></li> <li><a href="/wiki/Lorvotuzumab_mertansine" title="Lorvotuzumab mertansine">Lorvotuzumab mertansine</a><sup>§</sup></li> <li><a href="/wiki/Lumretuzumab" title="Lumretuzumab">Lumretuzumab</a><sup>§</sup></li> <li><a href="/wiki/Matuzumab" title="Matuzumab">Matuzumab</a><sup>§</sup></li> <li><a href="/wiki/Milatuzumab" title="Milatuzumab">Milatuzumab</a><sup>§</sup></li> <li><a href="/wiki/Naxitamab" title="Naxitamab">Naxitamab</a></li> <li><a href="/wiki/Nimotuzumab" title="Nimotuzumab">Nimotuzumab</a><sup>†</sup></li> <li><a href="/wiki/Obinutuzumab" title="Obinutuzumab">Obinutuzumab</a></li> <li><a href="/wiki/Ocaratuzumab" title="Ocaratuzumab">Ocaratuzumab</a><sup>§</sup></li> <li><a href="/wiki/Odronextamab" title="Odronextamab">Odronextamab</a></li> <li><a href="/wiki/Otlertuzumab" title="Otlertuzumab">Otlertuzumab</a><sup>§</sup></li> <li><a href="/wiki/Onartuzumab" title="Onartuzumab">Onartuzumab</a><sup>§</sup></li> <li><a href="/wiki/Oportuzumab_monatox" title="Oportuzumab monatox">Oportuzumab monatox</a><sup>†</sup></li> <li><a href="/wiki/Parsatuzumab" title="Parsatuzumab">Parsatuzumab</a><sup>§</sup></li> <li><a href="/wiki/Pertuzumab" title="Pertuzumab">Pertuzumab</a></li> <li><a href="/wiki/Pinatuzumab_vedotin" title="Pinatuzumab vedotin">Pinatuzumab vedotin</a><sup>§</sup></li> <li><a href="/wiki/Polatuzumab_vedotin" title="Polatuzumab vedotin">Polatuzumab vedotin</a></li> <li><a href="/wiki/Rosmantuzumab" title="Rosmantuzumab">Rosmantuzumab</a></li> <li><a href="/wiki/Rovalpituzumab_tesirine" title="Rovalpituzumab tesirine">Rovalpituzumab tesirine</a><sup>†</sup></li> <li><a href="/wiki/Sacituzumab_govitecan" title="Sacituzumab govitecan">Sacituzumab govitecan</a></li> <li><a href="/wiki/Sibrotuzumab" title="Sibrotuzumab">Sibrotuzumab</a><sup>§</sup></li> <li><a href="/wiki/Simtuzumab" title="Simtuzumab">Simtuzumab</a><sup>§</sup></li> <li><a href="/wiki/Sofituzumab_vedotin" title="Sofituzumab vedotin">Sofituzumab vedotin</a><sup>§</sup></li> <li><a href="/wiki/Yttrium_(90Y)_tacatuzumab_tetraxetan" title="Yttrium (90Y) tacatuzumab tetraxetan">Tacatuzumab tetraxetan</a><sup>§</sup></li> <li><a href="/wiki/Tigatuzumab" title="Tigatuzumab">Tigatuzumab</a><sup>§</sup></li> <li><a href="/wiki/Trastuzumab" title="Trastuzumab">Trastuzumab</a><sup>#</sup> (<a href="/wiki/Trastuzumab_deruxtecan" title="Trastuzumab deruxtecan">+deruxtecan</a> / <a href="/wiki/Trastuzumab_emtansine" title="Trastuzumab emtansine">+emtansine</a>)</li> <li><a href="/wiki/Tucotuzumab_celmoleukin" title="Tucotuzumab celmoleukin">Tucotuzumab celmoleukin</a><sup>§</sup></li> <li><a href="/wiki/Vandortuzumab_vedotin" title="Vandortuzumab vedotin">Vandortuzumab vedotin</a><sup>§</sup></li> <li><a href="/wiki/Vanucizumab" title="Vanucizumab">Vanucizumab</a><sup>§</sup></li> <li><a href="/wiki/Veltuzumab" title="Veltuzumab">Veltuzumab</a><sup>§</sup></li> <li><a href="/wiki/Vorsetuzumab_mafodotin" title="Vorsetuzumab mafodotin">Vorsetuzumab mafodotin</a><sup>§</sup></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Trifunctional_antibody" title="Trifunctional antibody">Rat/mouse hybrid</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Catumaxomab" title="Catumaxomab">Catumaxomab</a></li> <li><a href="/wiki/Ertumaxomab" title="Ertumaxomab">Ertumaxomab</a><sup>§</sup></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Chimeric + humanized</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Depatuxizumab_mafodotin" title="Depatuxizumab mafodotin">Depatuxizumab mafodotin</a><sup>†</sup></li> <li><a href="/wiki/Duvortuxizumab" title="Duvortuxizumab">Duvortuxizumab</a></li> <li><a href="/wiki/Ontuxizumab" title="Ontuxizumab">Ontuxizumab</a><sup>§</sup></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background: transparent; padding: 0px;"><div><div class="hlist"> <ul><li><sup>#</sup><a href="/wiki/WHO_Model_List_of_Essential_Medicines" title="WHO Model List of Essential Medicines">WHO-EM</a></li> <li><sup>‡</sup><a href="/wiki/List_of_withdrawn_drugs" title="List of withdrawn drugs">Withdrawn</a> from market</li> <li><a href="/wiki/Clinical_trial" title="Clinical trial">Clinical trials</a>: <ul><li><sup>†</sup><a href="/wiki/Phases_of_clinical_research#Phase_III" title="Phases of clinical research">Phase III</a></li> <li><sup>§</sup>Never to phase III</li></ul></li></ul> </div></div></td></tr></tbody></table></div>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1&useformat=desktop" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div 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