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class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/cameron-santoro"><i>Cameron Santoro</i></a></span></div></div><a href="/view/the-health-related-consequences-of-redlining"><a href="/view/the-health-related-consequences-of-redlining"><p class="mt-1 text-gray-800 text-[13px] line-clamp-6 text-hidden">The legacy of redlining continues to harm minority health, with Black individuals facing higher rates of health issues, linked to environmental factors and limited access to resources in regions previously redlined.</p></a></a></div></div><div class="flex-wrap w-[60%] flex "><a class="flex w-[50%] flex-col sm:pl-[35px] pl-[20px] pb-[35px] " href="/view/advancements-in-asthma-treatment-next-steps-and-insights-from-clinical-development-of-rilzabrutinib"><div class="w-full lg:h-[134px] h-[100px] relative bg-default-logo-background "><span 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src="/_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2Fd2afb412-3c3e-4f73-b3d6-2388078622a3%2F2jo692eom1yd-PTCE_COPD_Webinar_070224v1_800x385.png&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="object-cover" loading="lazy"/></noscript></span></div><div class="jsx-1777031866 content-wrap"><span class="jsx-1777031866 py-3 text-sm text-gray-500 text-left"><i class="jsx-1777031866">December 3rd 2024</i></span><div class="jsx-1777031866 w-full h-fit mb-4"><p class="jsx-1777031866 text-[18px] font-bold text-[#000000] text-left line-clamp-3 text-hidden">Managing Patients With COPD: Evidence-Based Care and Optimizing Value of New and Emerging Targeted Therapies</p></div><div class="jsx-1777031866 text-left text-[12px] text-[#000] py-6">1.0 Credit / Immunology, Pulmonology/Respiratory</div></div></div></a></div></div></div><div class="flex items-center space-x-4 border-0 border-b border-secondary select-none py-1"><h2 class="text-3xl text-primary">More News</h2></div><div class="flex flex-wrap w-full pb-4"><div class="jsx-ad50481d5ee26850 w-full h-full"><div><div><div class="text-[8px] text-center text-gray-500 hidden">Advertisement</div><div id="div-gpt-ad-infeed-1"></div></div></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/rilzabrutinib-improves-asthma-symptoms-in-the-first-2-weeks-of-treatment-study-finds"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/40852f145bab9c7f2afbbf9e9e57ea058485a08c-2880x1585.png?fit=crop&auto=format" alt="Leda Mannent, MD, global project head, Immunology and Inflammation, Sanofi" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">June 28th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/rilzabrutinib-improves-asthma-symptoms-in-the-first-2-weeks-of-treatment-study-finds">Rilzabrutinib Improves Asthma Symptoms in the First 2 Weeks of Treatment, Study Finds </a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/cameron-santoro">Cameron Santoro</a><span class="jsx-ad50481d5ee26850 mr-1 ml-[1px]"> </span><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/rilzabrutinib-improves-asthma-symptoms-in-the-first-2-weeks-of-treatment-study-finds"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Leda Mannent, MD, global project head, Immunology and Inflammation, Sanofi, discusses efficacy outcomes in patients with asthma who received rilzabrutinib. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/ipf-and-copd-associated-with-poor-covid-19-outcomes"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/0a3b531c3a36043fdc89946b72ed282ca0f94659-1325x725.jpg?fit=crop&auto=format" alt="Image of lungs and a doctor with a vial labelled COVID-19 | Image credit: Image credit: Mongkolchon - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">June 11th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/ipf-and-copd-associated-with-poor-covid-19-outcomes">IPF and COPD Associated With Poor COVID-19 Outcomes</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/kevin-kunzmann">Kevin Kunzmann</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/ipf-and-copd-associated-with-poor-covid-19-outcomes"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and other interstitial lung diseases are more significantly associated with poor 30-day outcomes from COVID-19 compared with asthma.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex md:hidden justify-center items-center"></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/racial-disparities-in-hospitalizations-ed-visits-among-medicaid-enrolled-children-with-asthma"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/daa7e39ea9b22ab502fccf25f5b9e0f421fa661c-4853x4335.jpg?fit=crop&auto=format" alt="Woman helps child with inhaler | peopleimages.com - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">May 31st 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/racial-disparities-in-hospitalizations-ed-visits-among-medicaid-enrolled-children-with-asthma">Racial Disparities in Hospitalizations, ED Visits Among Medicaid-Enrolled Children With Asthma</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/racial-disparities-in-hospitalizations-ed-visits-among-medicaid-enrolled-children-with-asthma"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Black children with asthma are disproportionately exposed to asthma triggers and access barriers, according to one study. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/the-impact-of-covid-19-on-asthma-diagnosis-health-care-utilization"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/c7f265d6b135af4626c69fa8c0a7761d72ef4ac3-5926x3951.jpg?fit=crop&auto=format" alt="Man holding paper model of lungs | Elena - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">May 28th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/the-impact-of-covid-19-on-asthma-diagnosis-health-care-utilization">The Impact of COVID-19 on Asthma Diagnosis, Health Care Utilization</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/the-impact-of-covid-19-on-asthma-diagnosis-health-care-utilization"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Posters presented at the American Thoracic Society (ATS) 2024 International Conference examined factors of the pandemic that may have influenced the clinical presentation and diagnosis of respiratory symptoms, as well as health care resource utilization for serious asthma outcomes. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/higher-prevalence-of-asthma-exacerbations-found-in-patients-with-insomnia"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/db42f68f7b9f804926f3e59c0f32272e1a28010d-7360x4912.jpg?fit=crop&auto=format" alt="Sleepless woman | StockPhotoPro - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">May 16th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/higher-prevalence-of-asthma-exacerbations-found-in-patients-with-insomnia">Higher Prevalence of Asthma Exacerbations Found in Patients With Insomnia </a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/higher-prevalence-of-asthma-exacerbations-found-in-patients-with-insomnia"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Underlying mood and sleep disorders may negatively affect asthma control, researchers find. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/avoidance-diets-linked-to-adult-onset-asthma-study-finds"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/67251ec7b83d3e07594e47eec0468a64eed50b80-7025x3900.jpg?fit=crop&auto=format" alt="Nutrition science and Food Sciences solution as a nutritionist or scientist with nutrients solving a puzzle and caloric intake as a dietary health concept for wellness and digestion | fitness-freshidea - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">May 9th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/avoidance-diets-linked-to-adult-onset-asthma-study-finds">Avoidance Diets Linked to Adult-Onset Asthma, Study Finds</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/avoidance-diets-linked-to-adult-onset-asthma-study-finds"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Asking patients about their diet is important when evaluating for adult-onset asthma, allergic disease, and aspirin-exacerbated respiratory disease (AERD). </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div><div><div class="text-[8px] text-center text-gray-500 hidden">Advertisement</div><div id="div-gpt-ad-infeed-7"></div></div></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/asthma-management-significantly-improved-after-guideline-education-intervention"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/4f396b590bad652bf8f9732bdff55185b3c08d43-5537x3746.jpg?fit=crop&auto=format" alt="Wooden blocks spell ASTHMA | gustavofrazao - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">May 1st 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/asthma-management-significantly-improved-after-guideline-education-intervention">Asthma Management Significantly Improved After Guideline Education Intervention</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/asthma-management-significantly-improved-after-guideline-education-intervention"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">The introduction of the Global Initiative for Asthma 2019 guidelines significantly improved treatment of children with mild asthma, according to one study. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/bronchial-thermoplasty-improves-ventilation-heterogeneity-in-severe-asthma"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/be6078ec555880c786c60a3900f9e2c8bea40eb9-4608x3456.jpg?fit=crop&auto=format" alt="Close up of doctor hand holding blue asthma inhaler and writing medical prescription on rx form for treatment asthma | Orawan - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">April 22nd 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/bronchial-thermoplasty-improves-ventilation-heterogeneity-in-severe-asthma">Bronchial Thermoplasty Improves Ventilation Heterogeneity in Severe Asthma</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/bronchial-thermoplasty-improves-ventilation-heterogeneity-in-severe-asthma"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Significant improvements were seen in ventilation heterogeneity in patients with severe asthma after 12 months of bronchial thermoplasty.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex md:hidden justify-center items-center"></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/what-we-re-reading-emergency-care-prices-vary-drug-shortages-at-record-high-asthma-medication-access-difficulties"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/703de894e882d8a6da8c19964dc1ca71b969d30c-2000x1046.png?fit=crop&auto=format" alt="what we're reading logo" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">April 18th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/what-we-re-reading-emergency-care-prices-vary-drug-shortages-at-record-high-asthma-medication-access-difficulties">What We’re Reading: Emergency Care Prices Vary; Drug Shortages at Record High; Asthma Medication Access Difficulties</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/ajmc-staff">AJMC Staff</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/what-we-re-reading-emergency-care-prices-vary-drug-shortages-at-record-high-asthma-medication-access-difficulties"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Prices for care at hospital trauma centers vary across hospitals; drug shortages reached a record high during the first quarter of 2024; although 3 of the biggest makers of asthma inhalers pledged to cap out-of-pocket costs for some US patients at $35, these do not apply to daily inhalers used by the youngest kids with asthma.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/covid-19-not-associated-with-asthma-development-in-children"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/c8d8cc356b783503ea19ac8ea4bcc4edb99d06dd-6720x4480.jpg?fit=crop&auto=format" alt="child in school wearing mask and spraying hand sanitizer | Seventyfour - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">April 17th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/covid-19-not-associated-with-asthma-development-in-children">COVID-19 Not Associated With Asthma Development in Children</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/covid-19-not-associated-with-asthma-development-in-children"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">COVID-19 likely does not increase the risk of asthma development in pediatric patients, research suggests. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/benralizumab-receives-fda-approval-as-add-on-maintenance-therapy-for-children-with-severe-asthma"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/72c0b40d03b8c0321305355753ee44397959760f-1200x724.jpg?fit=crop&auto=format" alt="FDA approval indication-Dzmitry-stock.adobe.com.jpeg" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">April 11th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/benralizumab-receives-fda-approval-as-add-on-maintenance-therapy-for-children-with-severe-asthma">Benralizumab Receives FDA Approval as Add-On Maintenance Therapy for Children With Severe Asthma </a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/benralizumab-receives-fda-approval-as-add-on-maintenance-therapy-for-children-with-severe-asthma"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">The approval of benralizumab (Fasenra) is supported by evidence from the phase 3 TATE study. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/study-finds-8-7-of-the-us-population-has-asthma"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/4f396b590bad652bf8f9732bdff55185b3c08d43-5537x3746.jpg?fit=crop&auto=format" alt="Wooden blocks spell ASTHMA | gustavofrazao - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">April 10th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/study-finds-8-7-of-the-us-population-has-asthma">Study Finds 8.7% of the US Population Has Asthma</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/study-finds-8-7-of-the-us-population-has-asthma"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Public health policies should address risk factors among individuals who are most at risk of asthma, researchers suggest. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div><div><div class="text-[8px] text-center text-gray-500 hidden">Advertisement</div><div id="div-gpt-ad-infeed-13"></div></div></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/biden-administration-extends-efforts-for-35-monthly-asthma-inhaler-price-cap"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/72902ca7581bbc42b1595fffcfab9508c3cc183f-7360x4912.jpg?fit=crop&auto=format" alt="Pills, thermometer, inhaler and money on a red background | Sebastian - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">April 4th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/biden-administration-extends-efforts-for-35-monthly-asthma-inhaler-price-cap">Biden Administration Extends Efforts for $35 Monthly Asthma Inhaler Price Cap</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/biden-administration-extends-efforts-for-35-monthly-asthma-inhaler-price-cap"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">President Joe Biden and Senator Bernie Sanders continue their push to cut the cost of asthma inhalers and prescription drugs in the US. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/ocs-treatment-significantly-reduces-tslp-levels-in-patients-with-asthma-study-finds"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/b1876eabc76ccb103ecdd9312ce1368cd90bec70-1200x800.jpg?fit=crop&auto=format" alt="Asthma treatment | Image Credit: © 279photo - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">April 2nd 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/ocs-treatment-significantly-reduces-tslp-levels-in-patients-with-asthma-study-finds">OCS Treatment Significantly Reduces TSLP Levels in Patients With Asthma, Study Finds</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/ocs-treatment-significantly-reduces-tslp-levels-in-patients-with-asthma-study-finds"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Patients with acute asthma exacerbations who do not suppress eosinophils after a course of oral corticosteroids (OCS) may have slower clinical recovery, according to one study. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/analysis-highlights-potential-gaps-between-popularity-credibility-of-asthma-related-tiktok-videos"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/d9908da6853b15192c3a0be7c9391bf4e09ac82a-1200x840.jpg?fit=crop&auto=format" alt="Tiktok on smart phone screen | Image Credit: © tashatuvango - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">March 28th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/analysis-highlights-potential-gaps-between-popularity-credibility-of-asthma-related-tiktok-videos">Analysis Highlights Potential Gaps Between Popularity, Credibility of Asthma-Related TikTok Videos</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/ajmc-contributor">AJMC Contributor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/analysis-highlights-potential-gaps-between-popularity-credibility-of-asthma-related-tiktok-videos"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">The researchers found that popularity of videos did not necessarily correlate with the quality of information provided in the video. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/dupilumab-reduces-asthma-symptoms-regardless-of-exacerbation-history-study-finds"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/e8d94af2f6477f46defb2fea3a348b92e342cb88-4073x3055.jpg?fit=crop&auto=format" alt="Young female in white t-shirt using blue asthma inhaler for relief asthma attack. Pharmaceutical products is used to prevent and treat wheezing and shortness of breath caused asthma or COPD. Close up | Orawan - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">March 25th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/dupilumab-reduces-asthma-symptoms-regardless-of-exacerbation-history-study-finds">Dupilumab Reduces Asthma Symptoms Regardless of Exacerbation History, Study Finds</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/dupilumab-reduces-asthma-symptoms-regardless-of-exacerbation-history-study-finds"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Dupilumab significantly reduced the risk of exacerbations compared with placebo in children with moderate to severe asthma, regardless of exacerbation history.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex md:hidden justify-center items-center"></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/air-pollution-linked-to-asthma-disparities-in-austin-neighborhoods"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/cbbbf61303f2c9a7759cfaf05791fd5667d0abef-5168x2907.jpg?fit=crop&auto=format" alt="Skyline of Austin, TX | madison500 - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">March 22nd 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/air-pollution-linked-to-asthma-disparities-in-austin-neighborhoods">Air Pollution Linked to Asthma Disparities in Austin Neighborhoods</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/air-pollution-linked-to-asthma-disparities-in-austin-neighborhoods"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Areas with high proportions of Black and Latinx residents face high rates of asthma-related emergency department visits, according to one study. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/copd-identified-as-most-common-severe-comorbidity-of-adult-asthma-study-finds"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/34651e29ad205046a76d20b16bae489226260919-3840x2160.jpg?fit=crop&auto=format" alt="Human Respiratory System Lungs Anatomy | magicmine - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">March 19th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/copd-identified-as-most-common-severe-comorbidity-of-adult-asthma-study-finds">COPD Identified as Most Common, Severe Comorbidity of Adult Asthma, Study Finds</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/copd-identified-as-most-common-severe-comorbidity-of-adult-asthma-study-finds"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">A study weighed the different comorbidities associated with asthma among a study population based in Finland. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div><div><div class="text-[8px] text-center text-gray-500 hidden">Advertisement</div><div id="div-gpt-ad-infeed-19"></div></div></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/oil-gas-flaring-linked-to-premature-deaths-asthma-exacerbations-among-children"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/15ce2ecc3b29490d0d335a095bed81017d6ee27b-3984x2622.jpg?fit=crop&auto=format" alt="oil and gas industry | christian42 - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">March 15th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/oil-gas-flaring-linked-to-premature-deaths-asthma-exacerbations-among-children">Oil, Gas Flaring Linked to Premature Deaths, Asthma Exacerbations Among Children </a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/oil-gas-flaring-linked-to-premature-deaths-asthma-exacerbations-among-children"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Controlling emissions can lead to significant improvements in public health in surrounding communities, according to one study. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/air-pollution-linked-to-childhood-asthma-by-early-middle-childhood"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/978f68cc54590c73e854b5949c0de0eab49e6646-2950x2094.jpg?fit=crop&auto=format" alt="Traffic-related air pollution | Sergiy Serdyuk - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">March 4th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/air-pollution-linked-to-childhood-asthma-by-early-middle-childhood">Air Pollution Linked to Childhood Asthma by Early, Middle Childhood</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/air-pollution-linked-to-childhood-asthma-by-early-middle-childhood"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Air pollution exposure during the first 3 years of life was associated with asthma incidence, according to one study. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/improved-clinical-outcomes-in-patients-with-severe-asthma-treated-with-biologic-therapies"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/544dfe8a1409da5770a886e63dab9240429fa157-3936x2624.jpg?fit=crop&auto=format" alt="Doctor writes medical prescription for asthma inhaler to asthmatic patient during medical consultation and examination in hospital | Goffkein - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">February 28th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/improved-clinical-outcomes-in-patients-with-severe-asthma-treated-with-biologic-therapies">Improved Clinical Outcomes in Patients With Severe Asthma Treated With Biologic Therapies </a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/improved-clinical-outcomes-in-patients-with-severe-asthma-treated-with-biologic-therapies"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Improvement across all asthma control parameters was achieved after 12 months of biologic treatment, according to one study. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/risk-based-program-decreases-asthma-related-health-care-resource-use-in-children"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/cc1ea246643b422cc658b96307d24fa6c936ee2e-5760x3840.jpg?fit=crop&auto=format" alt="Child is using an asthma inhaler | WavebreakmediaMicro - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">February 20th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/risk-based-program-decreases-asthma-related-health-care-resource-use-in-children">Risk-Based Program Decreases Asthma-Related Health Care Resource Use in Children</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/risk-based-program-decreases-asthma-related-health-care-resource-use-in-children"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Changing High-Risk Asthma in Memphis through Partnerships significantly decreased health care use related to asthma among children. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/dupilumab-improves-lung-function-asthma-exacerbations-in-children-study-finds"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/18bd85dcb74bede61175bf8d66523274d5385639-5317x3840.jpg?fit=crop&auto=format" alt="pulmonary function test using medical spirometer | Peakstock - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">February 15th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/dupilumab-improves-lung-function-asthma-exacerbations-in-children-study-finds">Dupilumab Improves Lung Function, Asthma Exacerbations in Children, Study Finds </a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/dupilumab-improves-lung-function-asthma-exacerbations-in-children-study-finds"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Children treated with dupilumab showed improved lung function compared with placebo group, according to one study. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/smoking-urban-housing-work-aggravated-asthma-linked-to-asthma-severity"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/0f0a2e5151cda804d06c3f57a26f35de5b1863d8-5760x3840.jpg?fit=crop&auto=format" alt="A man outside an office building has a severe asthma attack | Liubomir - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">February 12th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/smoking-urban-housing-work-aggravated-asthma-linked-to-asthma-severity">Smoking, Urban Housing, Work-Aggravated Asthma Linked to Asthma Severity</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/smoking-urban-housing-work-aggravated-asthma-linked-to-asthma-severity"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">These modifiable environmental factors were independently associated with asthma severity, according to one study. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div><div><div class="text-[8px] text-center text-gray-500 hidden">Advertisement</div><div id="div-gpt-ad-infeed-25"></div></div></div><div class="jsx-ad50481d5ee26850 flex md:hidden justify-center items-center"></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/real-world-users-of-triple-therapy-for-asthma-in-the-us"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/5421358c8f117ee86126333e135f08cf1e61ded6-778x382.png?fit=crop&auto=format" alt="AJMC" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">February 9th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/real-world-users-of-triple-therapy-for-asthma-in-the-us">Real-World Users of Triple Therapy for Asthma in the US</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/nadia-n-hansel-md">Nadia N. Hansel, MD</a><span class="jsx-ad50481d5ee26850 mr-1 ml-[1px]"> </span><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/carl-b-abbott-pharmd">Carl B. Abbott, PharmD</a><span class="jsx-ad50481d5ee26850 mr-1 ml-[1px]"> </span><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/carlyne-m-averell-ms">Carlyne M. Averell, MS</a><span class="jsx-ad50481d5ee26850 mr-1 ml-[1px]"> </span><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/guillaume-germain-msc">Guillaume Germain, MSc</a><span class="jsx-ad50481d5ee26850 mr-1 ml-[1px]"> </span><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/fran-ois-lalibert-ma">François Laliberté, MA</a><span class="jsx-ad50481d5ee26850 mr-1 ml-[1px]"> </span><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/malena-mahendran-msc">Malena Mahendran, MSc</a><span class="jsx-ad50481d5ee26850 mr-1 ml-[1px]"> </span><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/mei-s-duh-scd">Mei S. Duh, ScD</a><span class="jsx-ad50481d5ee26850 mr-1 ml-[1px]"> </span><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/russell-a-settipane-md">Russell A. Settipane, MD</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/real-world-users-of-triple-therapy-for-asthma-in-the-us"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">This retrospective cohort study evaluated baseline demographics, clinical characteristics, and treatment patterns of US patients with asthma who newly initiated single- or multiple-inhaler triple therapy.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/asthma-associated-with-increased-lung-cancer-risk-study-finds"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/34a595461e45614e9e2c58af2bb2d0a24df38fa6-3600x2400.jpg?fit=crop&auto=format" alt="Human lungs on scientific background | Crystal light - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">February 6th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/asthma-associated-with-increased-lung-cancer-risk-study-finds">Asthma Associated With Increased Lung Cancer Risk, Study Finds </a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/asthma-associated-with-increased-lung-cancer-risk-study-finds"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">A Mendelian randomization analysis supported an increasing causal relationship between asthma and lung cancer risk, particularly in smokers and lung squamous cell carcinoma. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/asthma-more-common-among-high-school-students-who-use-cannabis"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/7510ffa1b2c52cc06550e6d4c2307f9c859ccbb2-5375x3583.jpg?fit=crop&auto=format" alt="Jar of cannabis | S.Price - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">January 30th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/asthma-more-common-among-high-school-students-who-use-cannabis">Asthma More Common Among High School Students Who Use Cannabis</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/asthma-more-common-among-high-school-students-who-use-cannabis"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">This association remained significant even after controlling for cigarette use and demographic characteristics. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/dupilumab-effective-in-reducing-asthma-exacerbations-across-seasons-study-finds"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/eb003edecad5c380e218f7a15d8132495e28453a-5268x3951.jpg?fit=crop&auto=format" alt="Spring flowers representing human lungs | Science RF - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">January 25th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/dupilumab-effective-in-reducing-asthma-exacerbations-across-seasons-study-finds">Dupilumab Effective in Reducing Asthma Exacerbations Across Seasons, Study Finds </a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/dupilumab-effective-in-reducing-asthma-exacerbations-across-seasons-study-finds"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Dupilumab shows long-term efficacy across yearly seasons in patients with type 2 inflammatory asthma. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/prenatal-opioid-exposure-linked-to-asthma-in-children"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/5d25707dc4b1a32664c178c1cd2976781c47194b-5325x3552.jpg?fit=crop&auto=format" alt="child with inhaler | kichigin19 - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">January 23rd 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/prenatal-opioid-exposure-linked-to-asthma-in-children">Prenatal Opioid Exposure Linked to Asthma in Children </a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/prenatal-opioid-exposure-linked-to-asthma-in-children"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">A recent cohort study finds that prenatal opioid exposure is associated with increased risk of certain immune-related conditions, including asthma.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/using-machine-learning-models-to-predict-asthma-in-early-childhood"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/a44aa2ddc077464fef6954fe347fb2e995740fae-5884x4000.jpg?fit=crop&auto=format" alt="Child using inhaler mask | Anchalee - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">January 17th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/using-machine-learning-models-to-predict-asthma-in-early-childhood">Using Machine Learning Models to Predict Asthma in Early Childhood </a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/using-machine-learning-models-to-predict-asthma-in-early-childhood"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Asthma can be predicted using non-biological measurements from the age of 3 years, according to one study. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div></div><div class="w-full text-center flex justify-center pb-24"><a class="px-4 py-2 border-y border-r bg-primary text-white" 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","_key":"76af5f97a9cb"}],"_type":"block","style":"normal"},{"_key":"ee8c0cd8485a","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"f723aac91ebf"}],"_type":"block","style":"normal"},{"children":[{"_type":"span","marks":[],"text":"The findings from the double-blind placebo-controlled phase 2 ","_key":"8f8b27147d85"},{"_type":"span","marks":["c67e652b80d7"],"text":"study","_key":"cb0444d27bd9"},{"_type":"span","marks":[],"text":" were presented at the ","_key":"f1f8b13f923c"},{"_key":"6a5e88f34aee","_type":"span","marks":["839800d57acc"],"text":"American Thoracic Society (ATS) 2024 International Conference"},{"_type":"span","marks":[],"text":". ","_key":"70b337416fec"}],"_type":"block","style":"normal","_key":"5353280b5dd7","markDefs":[{"_key":"839800d57acc","nofollow":false,"blank":true,"_type":"link","href":"https://www.ajmc.com/conference/ats"},{"nofollow":true,"blank":true,"_type":"link","href":"https://www.sanofi.com/assets/dotcom/pressreleases/2024/2024-05-22-17-15-00-2886776-en.pdf","_key":"c67e652b80d7"}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"378ec4a730dd"}],"_type":"block","style":"normal","_key":"122e27545029"},{"_type":"block","style":"normal","_key":"72545d337595","markDefs":[],"children":[{"_type":"span","marks":["strong","underline"],"text":"Transcript","_key":"c5050e20483d"}]},{"children":[{"text":"How do you envision rilzabrutinib will impact real-world patient management and potentially reduce the health care burden?","_key":"4546f833d7690","_type":"span","marks":["strong"]}],"_type":"block","style":"normal","_key":"02e9fe5fef4b","markDefs":[]},{"_key":"bdb1aa607fc1","markDefs":[],"children":[{"_type":"span","marks":[],"text":"There are 2 key burdens for the health care system and for the patients today, and there are 2 major concerns. These are reducing the symptom burden and also preventing exacerbation. Despite the advent of biologics and many available therapies, there are more than 50% of the patients to day who still have uncontrolled symptoms. They carry on with their symptoms every day; they have wheeze, they have shortness of breath, they have cough, and they cannot manage their day-to-day living.","_key":"e736aa366e3f0"}],"_type":"block","style":"normal"},{"markDefs":[],"children":[{"text":"Therefore, there is a really high unmet need, despite current available therapies, to have something else. An advanced oral therapy would give these patients an additional option, but also [enable] the prescribers to reduce the symptom burden, and also to prevent the exacerbation. The result of this first rilzabrutinib study shows that rilzabrutinib has the potential to reduce the symptoms and reduce the loss of asthma control, which may predict future reduction in exacerbations.","_key":"26d80e5ab2730","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"af1bc8745764"},{"children":[{"_type":"span","marks":[],"text":"","_key":"e0845ab2edb3"}],"_type":"block","style":"normal","_key":"16e539f219e4","markDefs":[]},{"_key":"6fe732724b55","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"How do you see rilzabrutinib fitting into existing treatment regimens for moderate to severe asthma, and is there potential for combination therapy with inhaled corticosteroids or other biologics?","_key":"b2006e3622f6"}],"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"4f6cf5f9c631","markDefs":[],"children":[{"_type":"span","marks":[],"text":"As previously mentioned, more than 50% of patients remain uncontrolled despite being on inhaled corticosteroids, having other controlled therapy, or having biologics. So, these patients need additional options. In our study, we evaluated rilzabrutinib on top of inhaled corticosteroids and LABA [long-acting β-agonists], which is a controller, for the first 4 weeks. After, we withdrew their therapy, so we were able to evaluate in this first exploratory study the efficacy of rilzabrutinib [in improvement] in symptoms and the loss of asthma control while they were on inhaled corticosteroids and a controller, but also when they withdrew.","_key":"a19b6391b36a0"}]},{"style":"normal","_key":"3e6a2dc673df","markDefs":[],"children":[{"_key":"5f607b9257840","_type":"span","marks":[],"text":"The study indicates that rilzabrutinib has potential to improve symptoms on top of inhaled corticosteroids and LABA, but also the symptoms continued to improve despite the withdrawal. As we are moving forward—we just got this data—we are exploring all the opportunities of rilzabrutinib in the future. 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asthma guidelines need to focus more on the unmet needs of the patients whose severe asthma is not well controlled, said Tonya Winders, MBA, CEO and president of the Allergy \u0026 Asthma Network.","internalTag":["asthma","asthma guidelines","asthma care"],"contentCategory":{"_rev":"Yw6MEKZDMdk6hC2JCPjfiB","_type":"contentCategory","name":"Videos","_id":"ee14ccb3-3542-4414-9046-927be1198c76","_updatedAt":"2020-04-03T20:03:44Z","_createdAt":"2020-04-03T20:03:44Z"},"seoTag":["asthma guidelines","asthma","asthma care"],"link":"/view/tonya-winders-talks-about-the-daily-impact-of-asthma-guidelines-for-patients","title":"Tonya Winders Talks About the Daily Impact of Asthma Guidelines for 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","_key":"335d67e637b7","_type":"span","marks":[]}]},{"style":"normal","_key":"1d4729cf5756","markDefs":[],"children":[{"_type":"span","marks":["strong","underline"],"text":"Transcript","_key":"e16c1d96f7b3"}],"_type":"block"},{"style":"normal","_key":"8dd74d7fea27","markDefs":[],"children":[{"text":"How do asthma guidelines affect the day-to-day experience of patients with asthma?","_key":"8e4c32086fc5","_type":"span","marks":["strong"]}],"_type":"block"},{"markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"Winders: ","_key":"adce9492ba78"},{"marks":[],"text":"Well, the asthma guidelines definitely outline what is the standard of care, the clinical pathway that a patient should expect when they are diagnosed and then when they are reassessed on an ongoing basis by their provider. Unfortunately, there's a disconnect between what should happen and what often does. And so, that's what really [my] session will highlight. And again, we will bring to bear patient experience, patient voice, and exactly what some of those barriers may be.","_key":"316186c96952","_type":"span"}],"_type":"block","style":"normal","_key":"6a0bda6a21e8"},{"_key":"efc10989e5b2","markDefs":[],"children":[{"marks":["strong"],"text":"Does the experience differ on the degree of asthma severity?","_key":"ee63484c2f28","_type":"span"}],"_type":"block","style":"normal"},{"markDefs":[],"children":[{"text":"Winders: ","_key":"27f7cfdf6390","_type":"span","marks":["strong"]},{"_key":"ef843a57cb51","_type":"span","marks":[],"text":"The experience of patients of mild asthma vs moderate-to-severe asthma is very different. When it comes to daily impairment and impact on activities of daily living, it's very evident that the severe asthma population has the bulk of the unmet need and burden. And so, there is a disparity difference between those three, of mild, moderate, and severe. But even within the severe population, we see a vast difference between those that are uncontrolled, and those that are well controlled. So, really, the focus needs to be on the unmet needs of the area of those with poorly-controlled severe asthma most 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So, certainly a mild asthma, we've see areas of improvement and things like initial diagnosis and treatment, not prescribing albuterol alone for those mild asthma patients, is a critical effort that we are leading at the Global Allergy and Airways Patient Platform. And then, when we talk about the moderate-to-severe population, it's making sure that there's good inhaler technique, that patients have access to their controller preventer medication in addition to quick relief on a limited basis. But when their disease is uncontrolled or when it's escalating, when the severity level is such that it's not well managed or well controlled, that patients know where to turn and don't have to wait months or even years to get access to that level of specialty care because that's really where they will learn about some of the more targeted personalized treatments that are available for patients today.","_key":"b343cab54ac7","_type":"span"}],"_type":"block","style":"normal","_key":"f6b3b874d742"}],"_type":"article","source":null,"factCheckAuthorMapping":null},{"internalTag":["eosinophils","eosinophilic asthma"],"seoTag":["eosinophilic asthma","eosinophils"],"summary":"Michael E. 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Weschler: Differentiating Eosinophilic Asthma From Other Eosinophilic Conditions","body":[{"_type":"block","style":"normal","_key":"c93cc88ceab8","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"fe6c6ac7a970"}]},{"_type":"video","videoID":"6273901107001","source":"brightcove","_key":"8cd672c264fe"},{"_key":"58689ea64e3a","markDefs":[],"children":[{"text":"Michael E. Wechsler, MD, a pulmonologist at National Jewish Health, discusses the challenges associated with differentiating similar eosinophilic conditions, including eosinophilic asthma, from one another.","_key":"1a4f62c12642","_type":"span","marks":[]}],"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"fe5ba4ee7d7e","markDefs":[],"children":[{"_type":"span","marks":["strong","underline"],"text":"Transcript","_key":"7a858f56d9b9"}]},{"markDefs":[],"children":[{"marks":["strong"],"text":"What are some of the challenges with distinguishing eosinophilic asthma from other diagnoses associated with abnormal eosinophil activity?","_key":"d7993058c69b","_type":"span"}],"_type":"block","_key":"f0ca8632f4c6"},{"markDefs":[],"children":[{"text":"Well, you have to recognize that eosinophils are involved, and you can do that easily by evaluating the number of eosinophils in the blood. And so, with any disease state, you want to look for eosinophils at or in the tissue. And there aren't major challenges in terms of distinguishing from other eosinophilic conditions, other than the fact that there can be some overlap between the different conditions.","_key":"5ebc50fa8d04","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"cf3ce027ce92"},{"children":[{"marks":[],"text":"So for instance, there's eosinophilic asthma, that's basically just airway disease with eosinophils in the blood and/or the airway. Then, there's an entity called chronic eosinophilic pneumonia, which is basically eosinophilic asthma with some chronic sinus disease and pulmonary infiltrates. And then there is an entity called EGPA, or eosinophilic granulomatosis with polyangiitis. And that's an entity that's characterized by asthma, eosinophilia, sinus disease, pulmonary infiltrates, and then vasculitis in 1 or more end organ, including in neuropathy. And lastly, there are hypereosinophilic syndromes, which aren't really associated with asthma but have eosinophilia and organ involvement in systemic manifestations.","_key":"2e8d3421beb2","_type":"span"}],"_type":"block","style":"normal","_key":"f29b79110cec","markDefs":[]}],"contentCategory":{"name":"Videos","_id":"ee14ccb3-3542-4414-9046-927be1198c76","_updatedAt":"2020-04-03T20:03:44Z","_createdAt":"2020-04-03T20:03:44Z","_rev":"Yw6MEKZDMdk6hC2JCPjfiB","_type":"contentCategory"},"updatedOn":null},{"summary":"Michael E. Wechsler, MD, a pulmonologist at National Jewish Health, details the ways that the treatment of eosinophilic asthma differs from other forms of asthma.","_type":"article","title":"Dr Michael E. Weschler: Treating Eosinophilic Asthma vs Other Asthma Types","source":null,"_rev":"QrZLY65977D3s88wq8QVnX","body":[{"_type":"block","style":"normal","_key":"93af6dcab241","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"65673aac83a0"}]},{"_type":"video","videoID":"6273009545001","source":"brightcove","_key":"7bb20ed8eec4"},{"_key":"18c6cf4ba2e8","markDefs":[],"children":[{"marks":[],"text":"The treatment of eosinophilic asthma differs from other forms of asthma, explained Michael E. Wechsler, MD, a pulmonologist at National Jewish Health.","_key":"476d8a0fb85a","_type":"span"}],"_type":"block","style":"normal"},{"markDefs":[],"children":[{"_type":"span","marks":["strong","underline"],"text":"Transcript","_key":"3dc410f946f40"}],"_type":"block","style":"normal","_key":"9733dec8f7ba"},{"_type":"block","style":"normal","_key":"146455f5993f","markDefs":[],"children":[{"_key":"7e9802823bc0","_type":"span","marks":["strong"],"text":"How does treating eosinophilic asthma differ from treating other forms of asthma?"}]},{"_type":"block","style":"normal","_key":"2abe17bc28cc","markDefs":[],"children":[{"_type":"span","marks":[],"text":"So, what we've come to recognize is that people who have higher levels of eosinophils tend to have more risk of an exacerbation, lower lung function, and less likelihood of asthma control. So, historically, we treated all patients with asthma the same with inhaled corticosteroids and bronchodilators. When someone has eosinophilic asthma that's poorly controlled and that is associated with risk of exacerbations and loss of asthma control, we need to add on something else on top of the inhaled corticosteroids and long-acting bronchodilators. So, for those patients, there's now availability of a variety of different biologic therapies that target specific cytokines that play a role in eosinophilic inflammation. Those include therapies that target interleukin-5, or its receptor, or therapies that target interleukin [IL]-4 receptor alpha, and blocks both IL-4 and IL-13.","_key":"12faafce331b"}]},{"_key":"93870989ee45","markDefs":[],"children":[{"marks":[],"text":"By targeting those specific cytokines, on top of standard of care therapies, you can have a significant impact in terms of reducing exacerbations, improving lung function, and improving other asthma outcomes. 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corticosteroids"],"_updatedAt":"2022-01-03T19:44:44Z"},{"published":"2021-09-05T13:40:00.000Z","body":[{"markDefs":[],"children":[{"_key":"bf3ec51b05fd","_type":"span","marks":[],"text":""}],"_type":"block","style":"normal","_key":"0c197a15bf4f"},{"_key":"f51c95479ba5","_type":"video","videoID":"6270804862001","source":"brightcove"},{"_type":"block","style":"normal","_key":"48eb67b4d86e","markDefs":[],"children":[{"text":"William \"Andy\" Nish, MD, is a medical director and allergist and immunologist at Northeast Georgia Physicians Group in Gainesville, Georgia.","_key":"7afd5988cbd4","_type":"span","marks":[]}]},{"markDefs":[],"children":[{"_type":"span","marks":["underline","strong"],"text":"Transcript","_key":"5ef26051ee7b"}],"_type":"block","style":"normal","_key":"b6d3c24eead1"},{"style":"normal","_key":"23586c0d4ea3","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"If patients do have issues with medication adherence, for any reason, what are some strategies that clinicians and their staff can use to try to help them?","_key":"be64df02854f"}],"_type":"block"},{"markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"Nish: ","_key":"762682447fec"},{"_type":"span","marks":[],"text":"Well, first, it's important that we, as physicians, explain to them how important this is to do because sometimes they don't really get that it's an important thing. So, up to 25% of people with asthma don't really experience it, they're having trouble with their breathing. And so, sometimes I will use the analogy of [people with diabetes], they don't realize how much trouble they're having until they check their glucose. Or somebody with high blood pressure doesn't realize how high their blood pressure is until they check their blood pressure. And so, we'll do their breathing tests, and they're really not good, and so, I'll say, \"Hey, you know, I'm glad you feel well and yeah, if we do the test that measures how your breathing is doing, it tells us well, things really aren't so good and you're in danger of short-term being in the [emergency department] or being in a hospital.\" People still die from asthma in this country, 3500 people every year still die from asthma in the United States.","_key":"af98b24c1d85"}],"_type":"block","style":"normal","_key":"cff44e0045e7"},{"_type":"block","style":"normal","_key":"f7c92e462ffa","markDefs":[],"children":[{"_type":"span","marks":[],"text":"And so, we can't just take it lightly. It's not something that is just a nuisance, it's something that can be deadly. And then I tell them that long-term they're at risk of what's called remodelling, where your lungs have changes that are not fixable. And so, if you don't take care of yourself, currently, you're in danger for short term problems and also long term problems. So, I try to explain to them there's a reason we're doing this. And it's important. It's not just because I'm telling you to do it, it's for your health, and then try to make it easy. Certainly, some of the medicine we used to have were 4 times a day. Well, 4 times a day is like almost impossible. Two times a day shouldn't be that hard but then, fortunately, we have now once-a-day medicines like Breo [fluticasone furoate and vilanterol], Trelegy [fluticasone furoate, umeclidinium, and vilanterol], Arnuity [fluticasone furoate], and Alvesco [ciclesonide]. So, if you can't take it once-a-day, I don't know how much easier to make it. You can do things like set an alarm on your phone to take the medicine, put the medicine by your toothbrush, or deodorant, or something that you hopefully use regularly. Put it on the dinner table, put a calendar up and put an X on the calendar once you take the medicine.","_key":"886c69852389"}]},{"markDefs":[],"children":[{"text":"Particularly kids and particularly teenagers are just the worst about taking the medicine. They don't want to be different. They don't want to have to do something their friends don't do. They don't want to do something that marks them as somehow different or odd. And it's not a priority for them. So, I tell teenagers, I say, \"Look, you can earn your parents trust by taking the medicine.\" I say, \"If you don't take your medicine while you're sitting there right in front of your parents and they can sit there and see what you're doing, how do they know you're going to do what you're supposed to be doing when you're out there with your friends? So, you can earn their trust by doing what you're supposed to do when you're right there in front of them and then maybe they'll trust you more to do what you're supposed to do when you're out there in the world.\"","_key":"c812a4617184","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"a910e0274f20"}],"_rev":"EySuZeZvmrDk5KcS4HXO09","_id":"75f4ded2-d620-4605-a1d6-be7b1a6ec1ed","thumbnail":{"asset":{"url":"https://cdn.sanity.io/images/0vv8moc6/ajmc/fd311202475538f3e524ff243c5f0e530ae4f37f-1280x720.png","_rev":"7cbbWj8mwRohQ4aPc4h3Kc","mimeType":"image/png","_createdAt":"2021-07-30T14:10:27Z","originalFilename":"Screen Shot 2021-07-30 at 9.12.14 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Georgia.","_key":"d78bbd7fc9a4"}]},{"style":"normal","_key":"224c51dde4db","markDefs":[],"children":[{"_type":"span","marks":["underline","strong"],"text":"Transcript","_key":"682092c96f250"}],"_type":"block"},{"_key":"448749e857f3","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"Is it feasible to use predictive biomarkers to identify which therapies may work best for patients?","_key":"55087805bc5d"}],"_type":"block","style":"normal"},{"style":"normal","_key":"ed44d9650784","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Yes. In fact, to get somebody started on a biologic, we have to use certain biomarkers to get them qualified. So, for instance, there's sort of 3 categories of biologics, if you will. The first being Xolair, or omalizumab. And for that, they have to have a certain IgE [immunoglobulin E] level. Now, the bar is kind of low, it's 30 [KU/L]. So, that's not a whole lot of IgE. They have to have 30 [KU/L], and then they also have to be allergic to a perennial allergen, either skin testing or by RAST [radioallergosorbent test]. So, that's for Xolair.","_key":"b339c6e7ff8d"}],"_type":"block"},{"style":"normal","_key":"b6d2445dacd7","markDefs":[],"children":[{"_type":"span","marks":[],"text":"\nThen, there are 3 biologics that are anti-IL5 [interleuken-5], and that includes Nucala, or mepolizumab, and Fasenra, or benralizumab, and then Cinqair, which is reslizumab. So, for Nucala and Fasenra, you have to have at least around 200 eosinophils, and then for the Cinqair, reslizumab, based on their pivotal trials, you have to have more like 400 [eosinophils]. Those are the anti–IL-5 ones.","_key":"dcfcfc9fc9df"}],"_type":"block"},{"_key":"a5d9a7e434ae","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"793bfb6eb090"}],"_type":"block","style":"normal"},{"_key":"84b0a32bad0e","markDefs":[],"children":[{"marks":[],"text":"And so, just a segue here: If we're talking about type 2 inflammation, or TH-2 inflammation, then we're talking about IL-4, IL-5, and IL-13. Those are the ones that really drive that type 2 inflammation. They drive it by eosinophils, and so they help to increase the numbers and differentiation of eosinophils. So, those 3 we mentioned are anti-IL-5, and then Dupixent, or dupilumab, is actually anti–IL-4 and IL-13. So, those are the kind of 3 categories we have in terms of how they work.","_key":"cb4aed054654","_type":"span"}],"_type":"block","style":"normal"}],"url":{"current":"dr-william-andy-nish-details-the-list-of-medicines-targeting-asthma-biomarkers","_type":"slug"}}],"topArticlesData":[{"_id":"6fa1c666-9e9b-44b9-9405-211fe463f7b6","title":"The Health-Related Consequences of Redlining","summary":"The legacy of redlining continues to harm minority health, with Black individuals facing higher rates of health issues, linked to environmental factors and limited access to resources in regions previously redlined.","published":"2024-10-03T13:57:04.844Z","updatedOn":null,"factCheckAuthors":null,"url":"the-health-related-consequences-of-redlining","thumbnail":{"_type":"mainImage","alt":"Health equity. | Image Credit: Djavan Rodriguez - stock.adobe.com","caption":"The legacy of redlining continues to harm minority health, with Black individuals facing higher rates of health issues, linked to environmental factors and limited access to resources in regions previously redlined. | Image Credit: Djavan Rodriguez - stock.adobe.com","asset":{"_ref":"image-a86dcfac91e4404090cca56f20e7c4017ed43021-6000x4000-jpg","_type":"reference"}},"source":null,"authors":[{"displayName":"Cameron Santoro","url":"cameron-santoro"}]},{"source":null,"factCheckAuthors":null,"title":"Advancements in Asthma Treatment: Next Steps and Insights From Clinical Development of Rilzabrutinib","url":"advancements-in-asthma-treatment-next-steps-and-insights-from-clinical-development-of-rilzabrutinib","thumbnail":{"_type":"mainImage","alt":"Leda Mannent, MD, global project head, Immunology and Inflammation, Sanofi","asset":{"_ref":"image-40852f145bab9c7f2afbbf9e9e57ea058485a08c-2880x1585-png","_type":"reference"}},"published":"2024-08-01T19:40:05.718Z","updatedOn":null,"_id":"d4f8fba9-d73e-4a90-bfd0-828ebe7be132","summary":"Leda Mannent, MD, global project head, Immunology and Inflammation, Sanofi, outlines future steps for the clinical development of rilzabrutinib, as well as promising data to advance to phase 3 studies.","authors":[{"displayName":"Cameron Santoro","url":"cameron-santoro"},{"displayName":"Pearl Steinzor","url":"pearl-steinzor"}]},{"_id":"136fea75-5c23-4422-8e98-2c8f6eaacc32","thumbnail":{"_type":"mainImage","alt":"What We’re Reading: COVID-19 Vaccine and Fewer Asthma Symptoms; Cyberattack Reporting Rule; MA Misdiagnoses Drive Up Costs","asset":{"_type":"reference","_ref":"image-43a26cd2cd6a291365b4c989b3a7ac9474195aa7-1000x523-png"}},"updatedOn":null,"authors":[{"displayName":"AJMC Staff","url":"ajmc-staff"}],"source":null,"factCheckAuthors":null,"title":"What We’re Reading: COVID-19 Vaccine and Fewer Asthma Symptoms; Cyberattack Reporting Rule; MA Misdiagnoses Drive Up Costs","url":"what-we-re-reading-covid-19-vaccine-and-fewer-asthma-symptoms-cyberattack-reporting-rule-ma-misdiagnoses-drive-up-costs","summary":"Researchers link vaccination and reduced asthma symptoms; providers warn against overburdening and security risks; insurers’ practices lead to questionable diagnoses","published":"2024-07-08T14:25:22.258Z"},{"_id":"51c785a5-da5c-441e-906f-4b9380e37a06","thumbnail":{"_type":"mainImage","alt":"Patients with asthma are experiencing worse asthma symptoms with the effects of climate change. | Image Credit: alones - stock.adobe.com","caption":"Patients with asthma are experiencing worse asthma symptoms with the effects of climate change. | Image Credit: alones - stock.adobe.com","asset":{"_type":"reference","_ref":"image-442757cb07e85906abb8b5b0bac5d3c8f6bd1db2-6300x4200-jpg"}},"updatedOn":null,"title":"A Breathtaking Crisis, Part 2: Climate Change Worsens Asthma for Underserved Communities","url":"a-breathtaking-crisis-part-2-climate-change-worsens-asthma-for-underserved-communities","summary":"Underserved communities, already facing higher asthma prevalence due to social determinants of health, are disproportionately affected by the impact climate change is having on asthma exacerbations. 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