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Gastric folds - Wikipedia

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.infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox"><tbody><tr><th colspan="2" class="infobox-above" style="background-color:dimgray; color: white">Gastric folds</th></tr><tr><td colspan="2" class="infobox-image"><span class="mw-default-size" typeof="mw:File/Frameless"><a href="/wiki/File:Gastrointestinal_wall_of_human_stomach_hariadhi.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/c/cb/Gastrointestinal_wall_of_human_stomach_hariadhi.svg/250px-Gastrointestinal_wall_of_human_stomach_hariadhi.svg.png" decoding="async" width="250" height="250" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/cb/Gastrointestinal_wall_of_human_stomach_hariadhi.svg/375px-Gastrointestinal_wall_of_human_stomach_hariadhi.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/cb/Gastrointestinal_wall_of_human_stomach_hariadhi.svg/500px-Gastrointestinal_wall_of_human_stomach_hariadhi.svg.png 2x" data-file-width="512" data-file-height="512" /></a></span><div class="infobox-caption">Stomach</div></td></tr><tr><th colspan="2" class="infobox-header" style="background-color: #efefef">Details</th></tr><tr><th colspan="2" class="infobox-header" style="background-color: #efefef">Identifiers</th></tr><tr><th scope="row" class="infobox-label" style="padding-right:0.25em"><a href="/wiki/Latin" title="Latin">Latin</a></th><td class="infobox-data"><i>plicae gastricae</i></td></tr><tr><th scope="row" class="infobox-label" style="padding-right:0.25em"><a href="/wiki/Terminologia_Anatomica" title="Terminologia Anatomica">TA98</a></th><td class="infobox-data"><a rel="nofollow" class="external text" href="https://ifaa.unifr.ch/Public/EntryPage/TA98%20Tree/Entity%20TA98%20EN/05.5.01.028%20Entity%20TA98%20EN.htm">A05.5.01.028</a></td></tr><tr><th scope="row" class="infobox-label" style="padding-right:0.25em"><a href="/wiki/Terminologia_Anatomica" title="Terminologia Anatomica">TA2</a></th><td class="infobox-data"><a rel="nofollow" class="external text" href="https://ta2viewer.openanatomy.org/?id=2915">2915</a></td></tr><tr><th scope="row" class="infobox-label" style="padding-right:0.25em"><a href="/wiki/Foundational_Model_of_Anatomy" title="Foundational Model of Anatomy">FMA</a></th><td class="infobox-data"><a rel="nofollow" class="external text" href="https://bioportal.bioontology.org/ontologies/FMA/?p=classes&amp;conceptid=http%3A%2F%2Fpurl.org%2Fsig%2Font%2Ffma%2Ffma75653">75653</a></td></tr><tr><td colspan="2" class="infobox-below"><a href="/wiki/Anatomical_terminology" title="Anatomical terminology">Anatomical terminology</a><div style="text-align: right;"><small class="noprint">&#91;<a href="https://www.wikidata.org/wiki/Q5526792" class="extiw" title="d:Q5526792">edit on Wikidata</a>]</small></div></td></tr></tbody></table> <p>The <b>gastric folds</b> (or <b>gastric <a href="/wiki/Rugae" title="Rugae">rugae</a></b>) are coiled sections of tissue that exist in the <a href="/wiki/Mucous_membrane" title="Mucous membrane">mucosal</a> and <a href="/wiki/Submucosa" title="Submucosa">submucosal</a> layers of the <a href="/wiki/Stomach" title="Stomach">stomach</a>.<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup> They provide <a href="/wiki/Elasticity_(physics)" title="Elasticity (physics)">elasticity</a> by allowing the stomach to expand when a <a href="/wiki/Bolus_(digestion)" title="Bolus (digestion)">bolus</a> enters it. These folds stretch outward through the action of <a href="/wiki/Mechanoreceptors" class="mw-redirect" title="Mechanoreceptors">mechanoreceptors</a>, which respond to the increase in <a href="/wiki/Pressure" title="Pressure">pressure</a>.<sup id="cite_ref-:0_2-0" class="reference"><a href="#cite_note-:0-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> This allows the stomach to expand, therefore increasing the <a href="/wiki/Volume" title="Volume">volume</a> of the stomach without increasing pressure.<sup id="cite_ref-:0_2-1" class="reference"><a href="#cite_note-:0-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> They also provide the stomach with an increased <a href="/wiki/Surface_area" title="Surface area">surface area</a> for nutrient absorption during <a href="/wiki/Digestion" title="Digestion">digestion</a>.<sup id="cite_ref-:0_2-2" class="reference"><a href="#cite_note-:0-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> Gastric folds may be seen during <a href="/wiki/Esophagogastroduodenoscopy" title="Esophagogastroduodenoscopy">esophagogastroduodenoscopy</a> or in <a href="/wiki/Radiology" title="Radiology">radiological studies</a>.<sup id="cite_ref-:1_3-0" class="reference"><a href="#cite_note-:1-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Laparo_4-0" class="reference"><a href="#cite_note-Laparo-4"><span class="cite-bracket">&#91;</span>4<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Layers">Layers</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Gastric_folds&amp;action=edit&amp;section=1" title="Edit section: Layers"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The gastric folds consist of two layers: </p> <ul><li>Mucosal layer – This layer releases <a href="/wiki/Gastric_acid" title="Gastric acid">stomach acid</a>. It is the innermost layer of the stomach.<sup id="cite_ref-inner_5-0" class="reference"><a href="#cite_note-inner-5"><span class="cite-bracket">&#91;</span>5<span class="cite-bracket">&#93;</span></a></sup> It is affected by the hormone <a href="/wiki/Histamine" title="Histamine">histamine</a>, which signals it to release <a href="/wiki/Hydrochloric_acid" title="Hydrochloric acid">hydrochloric acid</a> (HCl).</li></ul> <ul><li>Sub-mucosal layer – This layer consists of different vessels and <a href="/wiki/Nerve" title="Nerve">nerves</a>, ganglion neurons, and <a href="/wiki/Adipose_tissue" title="Adipose tissue">adipose tissue</a>. It is the second layer of the stomach and supports the mucosa.<sup id="cite_ref-bionet_6-0" class="reference"><a href="#cite_note-bionet-6"><span class="cite-bracket">&#91;</span>6<span class="cite-bracket">&#93;</span></a></sup></li></ul> <figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/File:Gray%27s_Anatomy_-_Fig._1050.gif" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b9/Gray%27s_Anatomy_-_Fig._1050.gif/220px-Gray%27s_Anatomy_-_Fig._1050.gif" decoding="async" width="220" height="144" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b9/Gray%27s_Anatomy_-_Fig._1050.gif/330px-Gray%27s_Anatomy_-_Fig._1050.gif 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b9/Gray%27s_Anatomy_-_Fig._1050.gif/440px-Gray%27s_Anatomy_-_Fig._1050.gif 2x" data-file-width="500" data-file-height="327" /></a><figcaption>Drawing of the interior of the stomach.</figcaption></figure> <div class="mw-heading mw-heading2"><h2 id="Clinical_significance">Clinical significance</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Gastric_folds&amp;action=edit&amp;section=2" title="Edit section: Clinical significance"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Thickening of the gastric folds may be observed by <a href="/wiki/Endoscopy" title="Endoscopy">endoscopy</a> or <a href="/wiki/Radiography" title="Radiography">radiography</a> and may aid in the <a href="/wiki/Differential_diagnosis" title="Differential diagnosis">differential diagnosis</a> of many disease processes including:<sup id="cite_ref-:1_3-1" class="reference"><a href="#cite_note-:1-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> </p> <dl><dt><a href="/wiki/Gastritis" title="Gastritis">Gastritis</a></dt> <dd>The folds become very thick due to <a href="/wiki/Inflammation" title="Inflammation">inflammation</a>.<sup id="cite_ref-NORD_7-0" class="reference"><a href="#cite_note-NORD-7"><span class="cite-bracket">&#91;</span>7<span class="cite-bracket">&#93;</span></a></sup></dd> <dt><a href="/wiki/Peptic_ulcer_disease" title="Peptic ulcer disease">Peptic ulcer disease</a></dt> <dd><a href="/wiki/Ulcer_(dermatology)" title="Ulcer (dermatology)">Ulcers</a> cause breaks in the mucosa and cause erosion of the sub-mucosa.</dd> <dt><a href="/wiki/Zollinger-Ellison_syndrome" class="mw-redirect" title="Zollinger-Ellison syndrome">Zollinger-Ellison syndrome</a></dt> <dd><a href="/wiki/Gastrin" title="Gastrin">Gastrin</a> levels increase due to <a href="/wiki/Neoplasm" title="Neoplasm">tumors</a>, which cause an increase in the gastric fold size.<sup id="cite_ref-NORD_7-1" class="reference"><a href="#cite_note-NORD-7"><span class="cite-bracket">&#91;</span>7<span class="cite-bracket">&#93;</span></a></sup></dd> <dt><a href="/wiki/M%C3%A9n%C3%A9trier%27s_disease" title="Ménétrier&#39;s disease">Ménétrier's disease</a></dt> <dd>The mucosa pits are in excess causing thickening of the folds.<sup id="cite_ref-NORD_7-2" class="reference"><a href="#cite_note-NORD-7"><span class="cite-bracket">&#91;</span>7<span class="cite-bracket">&#93;</span></a></sup></dd> <dt><a href="/wiki/Carcinoma" title="Carcinoma">Carcinoma</a></dt> <dt><a href="/wiki/Helicobacter_pylori" title="Helicobacter pylori">Helicobacter pylori</a> infection</dt> <dd>Causes inflammation of the folds.</dd> <dt>Gastric <a href="/wiki/Syphilis" title="Syphilis">syphilis</a><sup id="cite_ref-Syph_8-0" class="reference"><a href="#cite_note-Syph-8"><span class="cite-bracket">&#91;</span>8<span class="cite-bracket">&#93;</span></a></sup></dt> <dt><a href="/wiki/Cytomegalovirus" title="Cytomegalovirus">Cytomegalovirus</a></dt> <dd>Mucosa change shape causing rugae enlargement.<sup id="cite_ref-Cron_Syn_9-0" class="reference"><a href="#cite_note-Cron_Syn-9"><span class="cite-bracket">&#91;</span>9<span class="cite-bracket">&#93;</span></a></sup></dd> <dt><a href="/wiki/Sarcoidosis" title="Sarcoidosis">Sarcoidosis</a></dt> <dd>Causes thickening of the folds.</dd></dl> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Gastric_folds&amp;action=edit&amp;section=3" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite id="CITEREFDavid.2009" class="citation book cs1">David., Shier (2009). <i>Hole's essentials of 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Boston: McGraw-Hill Higher Education. p.&#160;421. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a>&#160;<a href="/wiki/Special:BookSources/978-0077221355" title="Special:BookSources/978-0077221355"><bdi>978-0077221355</bdi></a>. <a href="/wiki/OCLC_(identifier)" class="mw-redirect" title="OCLC (identifier)">OCLC</a>&#160;<a rel="nofollow" class="external text" href="https://search.worldcat.org/oclc/171614173">171614173</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=book&amp;rft.btitle=Hole%27s+essentials+of+human+anatomy+%26+physiology&amp;rft.place=Boston&amp;rft.pages=421&amp;rft.edition=10th&amp;rft.pub=McGraw-Hill+Higher+Education&amp;rft.date=2009&amp;rft_id=info%3Aoclcnum%2F171614173&amp;rft.isbn=978-0077221355&amp;rft.aulast=David.&amp;rft.aufirst=Shier&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3AGastric+folds" class="Z3988"></span></span> </li> <li id="cite_note-:0-2"><span class="mw-cite-backlink">^ <a href="#cite_ref-:0_2-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-:0_2-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-:0_2-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMichelle.2013" class="citation book cs1">Michelle., McGuire (2013). <i>Nutritional sciences&#160;: from fundamentals to food</i>. 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href="/wiki/Template_talk:Gastrointestinal_tract" title="Template talk:Gastrointestinal tract"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Gastrointestinal_tract" title="Special:EditPage/Template:Gastrointestinal tract"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Anatomy_of_the_gastrointestinal_tract,_excluding_the_mouth" style="font-size:114%;margin:0 4em">Anatomy of the <a href="/wiki/Gastrointestinal_tract" title="Gastrointestinal tract">gastrointestinal tract</a>, excluding the <a href="/wiki/Human_mouth" title="Human mouth">mouth</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Gastrointestinal_tract#Upper_gastrointestinal_tract" title="Gastrointestinal tract">Upper</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Pharynx" title="Pharynx">Pharynx</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Pharyngeal_muscles" title="Pharyngeal muscles">Muscles</a></li> <li>Spaces <ul><li><a href="/wiki/Peripharyngeal_space" title="Peripharyngeal space">peripharyngeal </a></li> <li><a href="/wiki/Retropharyngeal_space" title="Retropharyngeal space">retropharyngeal </a></li> <li><a href="/wiki/Parapharyngeal_space" title="Parapharyngeal space">parapharyngeal </a></li> <li><a href="/wiki/Retrovisceral_space" title="Retrovisceral space">retrovisceral </a></li> <li><a href="/wiki/Danger_space" title="Danger space">danger</a></li> <li><a href="/wiki/Prevertebral_space" title="Prevertebral space">prevertebral</a></li></ul></li> <li><a href="/wiki/Pterygomandibular_raphe" title="Pterygomandibular raphe">Pterygomandibular raphe</a></li> <li><a href="/wiki/Pharyngeal_raphe" title="Pharyngeal raphe">Pharyngeal raphe</a></li> <li><a href="/wiki/Buccopharyngeal_fascia" title="Buccopharyngeal fascia">Buccopharyngeal fascia</a></li> <li><a href="/wiki/Pharyngobasilar_fascia" title="Pharyngobasilar fascia">Pharyngobasilar fascia</a></li> <li><a href="/wiki/Pyriform_sinus" title="Pyriform sinus">Pyriform sinus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Esophagus" title="Esophagus">Esophagus</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>Sphincters <ul><li><a href="/wiki/Esophagus#Sphincters" title="Esophagus">upper</a></li> <li><a href="/wiki/Esophagus#Sphincters" title="Esophagus">lower</a></li></ul></li> <li><a href="/wiki/Esophageal_gland" title="Esophageal gland">glands</a></li> <li><a href="/wiki/Crop_(anatomy)" title="Crop (anatomy)">crop</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Stomach" title="Stomach">Stomach</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>Curvatures <ul><li><a href="/wiki/Curvatures_of_the_stomach#Greater_curvature" title="Curvatures of the stomach">greater</a></li> <li><a href="/wiki/Curvatures_of_the_stomach#Lesser_curvature" title="Curvatures of the stomach">lesser</a></li> <li><a href="/wiki/Angular_incisure" title="Angular incisure">Angular incisure</a></li></ul></li> <li><a href="/wiki/Stomach#Sections" title="Stomach">Cardia</a></li> <li><a href="/wiki/Stomach#Structure" title="Stomach">Body</a></li> <li><a href="/wiki/Stomach#Structure" title="Stomach">Fundus</a></li> <li><a href="/wiki/Pylorus" title="Pylorus">Pylorus</a></li> <li><a href="/wiki/Gastric_mucosa" title="Gastric mucosa">Gastric mucosa</a></li> <li><a class="mw-selflink selflink">Gastric folds</a></li> <li>Microanatomy <ul><li><a href="/wiki/Gastric_pits" title="Gastric pits">Gastric pits</a></li> <li><a href="/wiki/Gastric_glands" title="Gastric glands">Gastric glands</a></li> <li><a href="/wiki/Cardiac_glands" class="mw-redirect" title="Cardiac glands">Cardiac glands</a></li> <li><a href="/wiki/Fundic_glands" class="mw-redirect" title="Fundic glands">Fundic glands</a></li> <li><a href="/wiki/Pylorus#Histology" title="Pylorus">Pyloric glands</a></li> <li><a href="/wiki/Foveolar_cell" title="Foveolar cell">Foveolar cells</a></li> <li><a href="/wiki/Parietal_cell" title="Parietal cell">Parietal cells</a></li> <li><a href="/wiki/Gastric_chief_cell" title="Gastric chief cell">Gastric chief cells</a></li> <li><a href="/wiki/Enterochromaffin-like_cell" title="Enterochromaffin-like cell">Enterochromaffin-like cells</a></li></ul></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Gastrointestinal_tract#Lower_gastrointestinal_tract" title="Gastrointestinal tract">Lower</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Small_intestine" title="Small intestine">Small intestine</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Microanatomy</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Intestinal_villus" title="Intestinal villus">Intestinal villi</a> <ul><li><a href="/wiki/Microvillus" title="Microvillus">Microvilli</a></li></ul></li> <li><a href="/wiki/Intestinal_gland" title="Intestinal gland">Intestinal glands</a></li> <li><a href="/wiki/Enterocyte" title="Enterocyte">Enterocytes</a></li> <li><a href="/wiki/Enteroendocrine_cell" title="Enteroendocrine cell">Enteroendocrine cells</a></li> <li><a href="/wiki/Goblet_cell" title="Goblet cell">Goblet cells</a></li> <li><a href="/wiki/Paneth_cell" title="Paneth cell">Paneth cells</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Duodenum" title="Duodenum">Duodenum</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Suspensory_muscle_of_duodenum" title="Suspensory muscle of duodenum">Suspensory muscle</a></li> <li><a href="/wiki/Major_duodenal_papilla" title="Major duodenal papilla">Major duodenal papilla</a></li> <li><a href="/wiki/Minor_duodenal_papilla" title="Minor duodenal papilla">Minor duodenal papilla</a></li> <li><a href="/wiki/Duodenojejunal_flexure" title="Duodenojejunal flexure">Duodenojejunal flexure</a></li> <li><a href="/wiki/Brunner%27s_glands" title="Brunner&#39;s glands">Brunner's glands</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Jejunum" title="Jejunum">Jejunum</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>No substructures</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Ileum" title="Ileum">Ileum</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Ileocecal_valve" title="Ileocecal valve">Ileocecal valve</a></li> <li><a href="/wiki/Peyer%27s_patch" title="Peyer&#39;s patch">Peyer's patches</a></li> <li><a href="/wiki/Microfold_cell" title="Microfold cell">Microfold cells</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Large_intestine" title="Large intestine">Large intestine</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Cecum" title="Cecum">Cecum</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Appendix_(anatomy)" title="Appendix (anatomy)">Appendix</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Large_intestine#Structure" title="Large intestine">Colon</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Ascending_colon" title="Ascending colon">Ascending colon</a></li> <li><a href="/wiki/Hepatic_flexure" class="mw-redirect" title="Hepatic flexure">Hepatic flexure</a></li> <li><a href="/wiki/Transverse_colon" title="Transverse colon">Transverse colon</a></li> <li><a href="/wiki/Splenic_flexure" class="mw-redirect" title="Splenic flexure">Splenic flexure</a></li> <li><a href="/wiki/Descending_colon" title="Descending colon">Descending colon</a></li> <li><a href="/wiki/Sigmoid_colon" title="Sigmoid colon">Sigmoid colon</a></li> <li>Continuous <ul><li><a href="/wiki/Taenia_coli" title="Taenia coli">taenia coli</a></li> <li><a href="/wiki/Haustrum_(anatomy)" title="Haustrum (anatomy)">haustra</a></li> <li><a href="/wiki/Epiploic_appendix" title="Epiploic appendix">epiploic appendix</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Rectum" title="Rectum">Rectum</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Transverse_folds_of_rectum" title="Transverse folds of rectum">Transverse folds</a></li> <li><a href="/wiki/Rectal_ampulla" class="mw-redirect" title="Rectal ampulla">Ampulla</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Anal_canal" title="Anal canal">Anal canal</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Human_anus" title="Human anus">Anus</a></li> <li><a href="/wiki/Anal_columns" title="Anal columns">Anal columns</a></li> <li><a href="/wiki/Anal_valves" title="Anal valves">Anal valves</a></li> <li><a href="/wiki/Anal_sinuses" title="Anal sinuses">Anal sinuses</a></li> <li><a href="/wiki/Pectinate_line" title="Pectinate line">Pectinate line</a></li> <li><a href="/wiki/Internal_anal_sphincter" title="Internal anal sphincter">Internal anal sphincter</a></li> <li><a href="/wiki/Intersphincteric_groove" class="mw-redirect" title="Intersphincteric groove">Intersphincteric groove</a></li> <li><a href="/wiki/External_anal_sphincter" title="External anal sphincter">External anal sphincter</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Gastrointestinal_wall" title="Gastrointestinal wall">Wall</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Serous_membrane" title="Serous membrane">Serosa</a> / <a href="/wiki/Adventitia" title="Adventitia">Adventitia</a></li> <li><a href="/wiki/Subserosa" title="Subserosa">Subserosa</a></li> <li><a href="/wiki/Muscular_layer" title="Muscular layer">Muscular layer</a></li> <li><a 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