CINXE.COM

<!DOCTYPE html> <html lang="en" xmlns:fb="http://www.facebook.com/2008/fbml" class="wf-loading"> <head prefix="og: https://ogp.me/ns# fb: https://ogp.me/ns/fb# academia: https://ogp.me/ns/fb/academia#"> <meta charset="utf-8"> <meta name=viewport content="width=device-width, initial-scale=1"> <meta rel="search" type="application/opensearchdescription+xml" href="/open_search.xml" title="Academia.edu"> <title>Nicola Sannolo | Università della Campania Luigi Vanvitelli - Academia.edu</title>  <link href="//a.academia-assets.com/images/favicons/favicon-production.ico" rel="shortcut icon" type="image/vnd.microsoft.icon"> <link rel="apple-touch-icon" sizes="57x57" href="//a.academia-assets.com/images/favicons/apple-touch-icon-57x57.png"> <link rel="apple-touch-icon" sizes="60x60" href="//a.academia-assets.com/images/favicons/apple-touch-icon-60x60.png"> <link rel="apple-touch-icon" sizes="72x72" href="//a.academia-assets.com/images/favicons/apple-touch-icon-72x72.png"> <link rel="apple-touch-icon" sizes="76x76" href="//a.academia-assets.com/images/favicons/apple-touch-icon-76x76.png"> <link rel="apple-touch-icon" sizes="114x114" href="//a.academia-assets.com/images/favicons/apple-touch-icon-114x114.png"> <link rel="apple-touch-icon" sizes="120x120" href="//a.academia-assets.com/images/favicons/apple-touch-icon-120x120.png"> <link rel="apple-touch-icon" sizes="144x144" href="//a.academia-assets.com/images/favicons/apple-touch-icon-144x144.png"> <link rel="apple-touch-icon" sizes="152x152" href="//a.academia-assets.com/images/favicons/apple-touch-icon-152x152.png"> <link rel="apple-touch-icon" sizes="180x180" href="//a.academia-assets.com/images/favicons/apple-touch-icon-180x180.png"> <link rel="icon" type="image/png" href="//a.academia-assets.com/images/favicons/favicon-32x32.png" sizes="32x32"> <link rel="icon" type="image/png" href="//a.academia-assets.com/images/favicons/favicon-194x194.png" sizes="194x194"> <link rel="icon" type="image/png" href="//a.academia-assets.com/images/favicons/favicon-96x96.png" sizes="96x96"> <link rel="icon" type="image/png" href="//a.academia-assets.com/images/favicons/android-chrome-192x192.png" sizes="192x192"> <link rel="icon" type="image/png" href="//a.academia-assets.com/images/favicons/favicon-16x16.png" sizes="16x16"> <link rel="manifest" href="//a.academia-assets.com/images/favicons/manifest.json"> <meta name="msapplication-TileColor" content="#2b5797"> <meta name="msapplication-TileImage" content="//a.academia-assets.com/images/favicons/mstile-144x144.png"> <meta name="theme-color" content="#ffffff"> <script> window.performance && window.performance.measure && window.performance.measure("Time To First Byte", "requestStart", "responseStart"); </script> <script> (function() { if (!window.URLSearchParams || !window.history || !window.history.replaceState) { return; } var searchParams = new URLSearchParams(window.location.search); var paramsToDelete = [ 'fs', 'sm', 'swp', 'iid', 'nbs', 'rcc', // related content category 'rcpos', // related content carousel position 'rcpg', // related carousel page 'rchid', // related content hit id 'f_ri', // research interest id, for SEO tracking 'f_fri', // featured research interest, for SEO tracking (param key without value) 'f_rid', // from research interest directory for SEO tracking 'f_loswp', // from research interest pills on LOSWP sidebar for SEO tracking 'rhid', // referrring hit id ]; if (paramsToDelete.every((key) => searchParams.get(key) === null)) { return; } paramsToDelete.forEach((key) => { searchParams.delete(key); }); var cleanUrl = new URL(window.location.href); cleanUrl.search = searchParams.toString(); history.replaceState({}, document.title, cleanUrl); })(); </script> <script async src="https://www.googletagmanager.com/gtag/js?id=G-5VKX33P2DS"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-5VKX33P2DS', { cookie_domain: 'academia.edu', send_page_view: false, }); gtag('event', 'page_view', { 'controller': "profiles/works", 'action': "summary", 'controller_action': 'profiles/works#summary', 'logged_in': 'false', 'edge': 'unknown', // Send nil if there is no A/B test bucket, in case some records get logged // with missing data - that way we can distinguish between the two cases. // ab_test_bucket should be of the form <ab_test_name>:<bucket> 'ab_test_bucket': null, }) </script> <script type="text/javascript"> window.sendUserTiming = function(timingName) { if (!(window.performance && window.performance.measure)) return; var entries = window.performance.getEntriesByName(timingName, "measure"); if (entries.length !== 1) return; var timingValue = Math.round(entries[0].duration); gtag('event', 'timing_complete', { name: timingName, value: timingValue, event_category: 'User-centric', }); }; window.sendUserTiming("Time To First Byte"); </script> <meta name="csrf-param" content="authenticity_token" /> <meta name="csrf-token" content="t8WVU1FLjFhSXqO4hZQPetWZUYm645EM7pfJs0Ii2iLdz47rhy/8b+qaOUx0IOfOea6BpRAnJjTWqWx/3PNkIg==" /> <link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/wow-77f7b87cb1583fc59aa8f94756ebfe913345937eb932042b4077563bebb5fb4b.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/social/home-9e8218e1301001388038e3fc3427ed00d079a4760ff7745d1ec1b2d59103170a.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/heading-b2b823dd904da60a48fd1bfa1defd840610c2ff414d3f39ed3af46277ab8df3b.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/button-3cea6e0ad4715ed965c49bfb15dedfc632787b32ff6d8c3a474182b231146ab7.css" /><link crossorigin="" href="https://fonts.gstatic.com/" rel="preconnect" /><link href="https://fonts.googleapis.com/css2?family=DM+Sans:ital,opsz,wght@0,9..40,100..1000;1,9..40,100..1000&family=Gupter:wght@400;500;700&family=IBM+Plex+Mono:wght@300;400&family=Material+Symbols+Outlined:opsz,wght,FILL,GRAD@20,400,0,0&display=swap" rel="stylesheet" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/common-10fa40af19d25203774df2d4a03b9b5771b45109c2304968038e88a81d1215c5.css" /> <meta name="author" content="nicola sannolo" /> <meta name="description" content="Nicola Sannolo, Università della Campania Luigi Vanvitelli: 51 Followers, 38 Following, 69 Research papers. Research interests: Multivariate Analysis, Mass…" /> <meta name="google-site-verification" content="bKJMBZA7E43xhDOopFZkssMMkBRjvYERV-NaN4R6mrs" /> <script> var $controller_name = 'works'; var $action_name = "summary"; var $rails_env = 'production'; var $app_rev = '92477ec68c09d28ae4730a4143c926f074776319'; var $domain = 'academia.edu'; var $app_host = "academia.edu"; var $asset_host = "academia-assets.com"; var $start_time = new Date().getTime(); var $recaptcha_key = "6LdxlRMTAAAAADnu_zyLhLg0YF9uACwz78shpjJB"; var $recaptcha_invisible_key = "6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj"; var $disableClientRecordHit = false; </script> <script> window.Aedu = { hit_data: null }; window.Aedu.SiteStats = {"premium_universities_count":15276,"monthly_visitors":"113 million","monthly_visitor_count":113458213,"monthly_visitor_count_in_millions":113,"user_count":277570013,"paper_count":55203019,"paper_count_in_millions":55,"page_count":432000000,"page_count_in_millions":432,"pdf_count":16500000,"pdf_count_in_millions":16}; window.Aedu.serverRenderTime = new Date(1732830282000); window.Aedu.timeDifference = new Date().getTime() - 1732830282000; window.Aedu.isUsingCssV1 = false; window.Aedu.enableLocalization = true; window.Aedu.activateFullstory = false; window.Aedu.serviceAvailability = { status: {"attention_db":"on","bibliography_db":"on","contacts_db":"on","email_db":"on","indexability_db":"on","mentions_db":"on","news_db":"on","notifications_db":"on","offsite_mentions_db":"on","redshift":"on","redshift_exports_db":"on","related_works_db":"on","ring_db":"on","user_tests_db":"on"}, serviceEnabled: function(service) { return this.status[service] === "on"; }, readEnabled: function(service) { return this.serviceEnabled(service) || this.status[service] === "read_only"; }, }; window.Aedu.viewApmTrace = function() { // Check if x-apm-trace-id meta tag is set, and open the trace in APM // in a new window if it is. var apmTraceId = document.head.querySelector('meta[name="x-apm-trace-id"]'); if (apmTraceId) { var traceId = apmTraceId.content; // Use trace ID to construct URL, an example URL looks like: // https://app.datadoghq.com/apm/traces?query=trace_id%31298410148923562634 var apmUrl = 'https://app.datadoghq.com/apm/traces?query=trace_id%3A' + traceId; window.open(apmUrl, '_blank'); } }; </script>  <link href="https://fonts.googleapis.com/css?family=Roboto:100,100i,300,300i,400,400i,500,500i,700,700i,900,900i" rel="stylesheet"> <link href="//maxcdn.bootstrapcdn.com/font-awesome/4.3.0/css/font-awesome.min.css" rel="stylesheet"> <link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/libraries-a9675dcb01ec4ef6aa807ba772c7a5a00c1820d3ff661c1038a20f80d06bb4e4.css" /> <link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/academia-bdb9e8c097f01e611f2fc5e2f1a9dc599beede975e2ae5629983543a1726e947.css" /> <link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system_legacy-056a9113b9a0f5343d013b29ee1929d5a18be35fdcdceb616600b4db8bd20054.css" /> <script src="//a.academia-assets.com/assets/webpack_bundles/runtime-bundle-005434038af4252ca37c527588411a3d6a0eabb5f727fac83f8bbe7fd88d93bb.js"></script> <script src="//a.academia-assets.com/assets/webpack_bundles/webpack_libraries_and_infrequently_changed.wjs-bundle-bae13f9b51961d5f1e06008e39e31d0138cb31332e8c2e874c6d6a250ec2bb14.js"></script> <script src="//a.academia-assets.com/assets/webpack_bundles/core_webpack.wjs-bundle-19a25d160d01bde427443d06cd6b810c4c92c6026e7cb31519e06313eb24ed90.js"></script> <script src="//a.academia-assets.com/assets/webpack_bundles/sentry.wjs-bundle-5fe03fddca915c8ba0f7edbe64c194308e8ce5abaed7bffe1255ff37549c4808.js"></script> <script> jade = window.jade || {}; jade.helpers = window.$h; jade._ = window._; </script>  <script id="tag-manager-head-root">(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start': new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0], j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src= 'https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f); })(window,document,'script','dataLayer_old','GTM-5G9JF7Z');</script>  <script> window.gptadslots = []; window.googletag = window.googletag || {}; window.googletag.cmd = window.googletag.cmd || []; </script> <script type="text/javascript"> // TODO(jacob): This should be defined, may be rare load order problem. // Checking if null is just a quick fix, will default to en if unset. // Better fix is to run this immedietely after I18n is set. if (window.I18n != null) { I18n.defaultLocale = "en"; I18n.locale = "en"; I18n.fallbacks = true; } </script> <link rel="canonical" href="https://unina2.academia.edu/NicolaSannolo" /> </head>   <body class='c-profiles/works a-summary logged_out'>  <div id="fb-root"></div><script>window.fbAsyncInit = function() { FB.init({ appId: "2369844204", version: "v8.0", status: true, cookie: true, xfbml: true }); // Additional initialization code. if (window.InitFacebook) { // facebook.ts already loaded, set it up. window.InitFacebook(); } else { // Set a flag for facebook.ts to find when it loads. window.academiaAuthReadyFacebook = true; } };</script><script>window.fbAsyncLoad = function() { // Protection against double calling of this function if (window.FB) { return; } (function(d, s, id){ var js, fjs = d.getElementsByTagName(s)[0]; if (d.getElementById(id)) {return;} js = d.createElement(s); js.id = id; js.src = "//connect.facebook.net/en_US/sdk.js"; fjs.parentNode.insertBefore(js, fjs); }(document, 'script', 'facebook-jssdk')); } if (!window.defer_facebook) { // Autoload if not deferred window.fbAsyncLoad(); } else { // Defer loading by 5 seconds setTimeout(function() { window.fbAsyncLoad(); }, 5000); }</script> <div id="google-root"></div><script>window.loadGoogle = function() { if (window.InitGoogle) { // google.ts already loaded, set it up. window.InitGoogle("331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b"); } else { // Set a flag for google.ts to use when it loads. window.GoogleClientID = "331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b"; } };</script><script>window.googleAsyncLoad = function() { // Protection against double calling of this function (function(d) { var js; var id = 'google-jssdk'; var ref = d.getElementsByTagName('script')[0]; if (d.getElementById(id)) { return; } js = d.createElement('script'); js.id = id; js.async = true; js.onload = loadGoogle; js.src = "https://accounts.google.com/gsi/client" ref.parentNode.insertBefore(js, ref); }(document)); } if (!window.defer_google) { // Autoload if not deferred window.googleAsyncLoad(); } else { // Defer loading by 5 seconds setTimeout(function() { window.googleAsyncLoad(); }, 5000); }</script> <div id="tag-manager-body-root">  <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-5G9JF7Z" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript>   <script> window.addEventListener('load', function() { if (document.querySelector('input[name="commit"]')) { document.querySelector('input[name="commit"]').addEventListener('click', function() { gtag('event', 'click', { event_category: 'button', event_label: 'Log In' }) }) } }); </script> </div> <script>var _comscore = _comscore || []; _comscore.push({ c1: "2", c2: "26766707" }); (function() { var s = document.createElement("script"), el = document.getElementsByTagName("script")[0]; s.async = true; s.src = (document.location.protocol == "https:" ? "https://sb" : "http://b") + ".scorecardresearch.com/beacon.js"; el.parentNode.insertBefore(s, el); })();</script><img src="https://sb.scorecardresearch.com/p?c1=2&c2=26766707&cv=2.0&cj=1" style="position: absolute; visibility: hidden" /> <div id='react-modal'></div> <div class='DesignSystem'> <a class='u-showOnFocus' href='#site'> Skip to main content </a> </div> <div id="upgrade_ie_banner" style="display: none;"><p>Academia.edu no longer supports Internet Explorer.</p><p>To browse Academia.edu and the wider internet faster and more securely, please take a few seconds to <a href="https://www.academia.edu/upgrade-browser">upgrade your browser</a>.</p></div><script>// Show this banner for all versions of IE if (!!window.MSInputMethodContext || /(MSIE)/.test(navigator.userAgent)) { document.getElementById('upgrade_ie_banner').style.display = 'block'; }</script> <div class="DesignSystem bootstrap ShrinkableNav"><div class="navbar navbar-default main-header"><div class="container-wrapper" id="main-header-container"><div class="container"><div class="navbar-header"><div class="nav-left-wrapper u-mt0x"><div class="nav-logo"><a data-main-header-link-target="logo_home" href="https://www.academia.edu/"><img class="visible-xs-inline-block" style="height: 24px;" alt="Academia.edu" src="//a.academia-assets.com/images/academia-logo-redesign-2015-A.svg" width="24" height="24" /><img width="145.2" height="18" class="hidden-xs" style="height: 24px;" alt="Academia.edu" src="//a.academia-assets.com/images/academia-logo-redesign-2015.svg" /></a></div><div class="nav-search"><div class="SiteSearch-wrapper select2-no-default-pills"><form class="js-SiteSearch-form DesignSystem" action="https://www.academia.edu/search" accept-charset="UTF-8" method="get"><input name="utf8" type="hidden" value="✓" autocomplete="off" /><i class="SiteSearch-icon fa fa-search u-fw700 u-positionAbsolute u-tcGrayDark"></i><input class="js-SiteSearch-form-input SiteSearch-form-input form-control" data-main-header-click-target="search_input" name="q" placeholder="Search" type="text" value="" /></form></div></div></div><div class="nav-right-wrapper pull-right"><ul class="NavLinks js-main-nav list-unstyled"><li class="NavLinks-link"><a class="js-header-login-url Button Button--inverseGray Button--sm u-mb4x" id="nav_log_in" rel="nofollow" href="https://www.academia.edu/login">Log In</a></li><li class="NavLinks-link u-p0x"><a class="Button Button--inverseGray Button--sm u-mb4x" rel="nofollow" href="https://www.academia.edu/signup">Sign Up</a></li></ul><button class="hidden-lg hidden-md hidden-sm u-ml4x navbar-toggle collapsed" data-target=".js-mobile-header-links" data-toggle="collapse" type="button"><span class="icon-bar"></span><span class="icon-bar"></span><span class="icon-bar"></span></button></div></div><div class="collapse navbar-collapse js-mobile-header-links"><ul class="nav navbar-nav"><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/login">Log In</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/signup">Sign Up</a></li><li class="u-borderColorGrayLight u-borderBottom1 js-mobile-nav-expand-trigger"><a href="#">more&nbsp<span class="caret"></span></a></li><li><ul class="js-mobile-nav-expand-section nav navbar-nav u-m0x collapse"><li class="u-borderColorGrayLight u-borderBottom1"><a rel="false" href="https://www.academia.edu/about">About</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/press">Press</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://medium.com/@academia">Blog</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="false" href="https://www.academia.edu/documents">Papers</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/terms">Terms</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/privacy">Privacy</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/copyright">Copyright</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/hiring"><i class="fa fa-briefcase"></i> We're Hiring!</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://support.academia.edu/"><i class="fa fa-question-circle"></i> Help Center</a></li><li class="js-mobile-nav-collapse-trigger u-borderColorGrayLight u-borderBottom1 dropup" style="display:none"><a href="#">less&nbsp<span class="caret"></span></a></li></ul></li></ul></div></div></div><script>(function(){ var $moreLink = $(".js-mobile-nav-expand-trigger"); var $lessLink = $(".js-mobile-nav-collapse-trigger"); var $section = $('.js-mobile-nav-expand-section'); $moreLink.click(function(ev){ ev.preventDefault(); $moreLink.hide(); $lessLink.show(); $section.collapse('show'); }); $lessLink.click(function(ev){ ev.preventDefault(); $moreLink.show(); $lessLink.hide(); $section.collapse('hide'); }); })() if ($a.is_logged_in() || false) { new Aedu.NavigationController({ el: '.js-main-nav', showHighlightedNotification: false }); } else { $(".js-header-login-url").attr("href", $a.loginUrlWithRedirect()); } Aedu.autocompleteSearch = new AutocompleteSearch({el: '.js-SiteSearch-form'});</script></div></div> <div id='site' class='fixed'> <div id="content" class="clearfix"> <script>document.addEventListener('DOMContentLoaded', function(){ var $dismissible = $(".dismissible_banner"); $dismissible.click(function(ev) { $dismissible.hide(); }); });</script> <script src="//a.academia-assets.com/assets/webpack_bundles/profile.wjs-bundle-e032f1d55548c2f2dee4eac9fe52f38beaf13471f2298bb2ea82725ae930b83c.js" defer="defer"></script><script>Aedu.rankings = { showPaperRankingsLink: false } $viewedUser = Aedu.User.set_viewed( {"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo","photo":"/images/s65_no_pic.png","has_photo":false,"department":{"id":1568826,"name":"DIPARTIMENTO DI MEDICINA SPERIMENTALE","url":"https://unina2.academia.edu/Departments/DIPARTIMENTO_DI_MEDICINA_SPERIMENTALE/Documents","university":{"id":3444,"name":"Università della Campania Luigi Vanvitelli","url":"https://unina2.academia.edu/"}},"position":"Faculty Member","position_id":1,"is_analytics_public":false,"interests":[{"id":41482,"name":"Multivariate Analysis","url":"https://www.academia.edu/Documents/in/Multivariate_Analysis"},{"id":5769,"name":"Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Mass_Spectrometry"},{"id":256975,"name":"Mathematics and Computer Science","url":"https://www.academia.edu/Documents/in/Mathematics_and_Computer_Science"},{"id":15709,"name":"Sustainable Construction","url":"https://www.academia.edu/Documents/in/Sustainable_Construction"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":166448,"name":"Gas Chromatography","url":"https://www.academia.edu/Documents/in/Gas_Chromatography"},{"id":246560,"name":"High Pressure Liquid Chromatography","url":"https://www.academia.edu/Documents/in/High_Pressure_Liquid_Chromatography"}]} ); if ($a.is_logged_in() && $viewedUser.is_current_user()) { $('body').addClass('profile-viewed-by-owner'); } $socialProfiles = []</script><div id="js-react-on-rails-context" style="display:none" data-rails-context="{"inMailer":false,"i18nLocale":"en","i18nDefaultLocale":"en","href":"https://unina2.academia.edu/NicolaSannolo","location":"/NicolaSannolo","scheme":"https","host":"unina2.academia.edu","port":null,"pathname":"/NicolaSannolo","search":null,"httpAcceptLanguage":null,"serverSide":false}"></div> <div class="js-react-on-rails-component" style="display:none" data-component-name="ProfileCheckPaperUpdate" data-props="{}" data-trace="false" data-dom-id="ProfileCheckPaperUpdate-react-component-10c0e086-614b-42b5-9540-21a71267f99c"></div> <div id="ProfileCheckPaperUpdate-react-component-10c0e086-614b-42b5-9540-21a71267f99c"></div> <div class="DesignSystem"><div class="onsite-ping" id="onsite-ping"></div></div><div class="profile-user-info DesignSystem"><div class="social-profile-container"><div class="left-panel-container"><div class="user-info-component-wrapper"><div class="user-summary-cta-container"><div class="user-summary-container"><div class="social-profile-avatar-container"><img class="profile-avatar u-positionAbsolute" border="0" alt="" src="//a.academia-assets.com/images/s200_no_pic.png" /></div><div class="title-container"><h1 class="ds2-5-heading-sans-serif-sm">Nicola Sannolo</h1><div class="affiliations-container fake-truncate js-profile-affiliations"><div><a class="u-tcGrayDarker" href="https://unina2.academia.edu/">Università della Campania Luigi Vanvitelli</a>, <a class="u-tcGrayDarker" href="https://unina2.academia.edu/Departments/DIPARTIMENTO_DI_MEDICINA_SPERIMENTALE/Documents">DIPARTIMENTO DI MEDICINA SPERIMENTALE</a>, <span class="u-tcGrayDarker">Faculty Member</span></div></div></div></div><div class="sidebar-cta-container"><button class="ds2-5-button hidden profile-cta-button grow js-profile-follow-button" data-broccoli-component="user-info.follow-button" data-click-track="profile-user-info-follow-button" data-follow-user-fname="Nicola" data-follow-user-id="36993140" data-follow-user-source="profile_button" data-has-google="false"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">add</span>Follow</button><button class="ds2-5-button hidden profile-cta-button grow js-profile-unfollow-button" data-broccoli-component="user-info.unfollow-button" data-click-track="profile-user-info-unfollow-button" data-unfollow-user-id="36993140"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">done</span>Following</button></div></div><div class="user-stats-container"><a><div class="stat-container js-profile-followers"><p class="label">Followers</p><p class="data">51</p></div></a><a><div class="stat-container js-profile-followees" data-broccoli-component="user-info.followees-count" data-click-track="profile-expand-user-info-following"><p class="label">Following</p><p class="data">38</p></div></a><a><div class="stat-container js-profile-coauthors" data-broccoli-component="user-info.coauthors-count" data-click-track="profile-expand-user-info-coauthors"><p class="label">Co-authors</p><p class="data">20</p></div></a><span><div class="stat-container"><p class="label"><span class="js-profile-total-view-text">Public Views</span></p><p class="data"><span class="js-profile-view-count"></span></p></div></span></div><div class="ri-section"><div class="ri-section-header"><span>Interests</span><a class="ri-more-link js-profile-ri-list-card" data-click-track="profile-user-info-primary-research-interest" data-has-card-for-ri-list="36993140">View All (7)</a></div><div class="ri-tags-container"><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="36993140" href="https://www.academia.edu/Documents/in/Multivariate_Analysis"><div id="js-react-on-rails-context" style="display:none" data-rails-context="{"inMailer":false,"i18nLocale":"en","i18nDefaultLocale":"en","href":"https://unina2.academia.edu/NicolaSannolo","location":"/NicolaSannolo","scheme":"https","host":"unina2.academia.edu","port":null,"pathname":"/NicolaSannolo","search":null,"httpAcceptLanguage":null,"serverSide":false}"></div> <div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Multivariate Analysis"]}" data-trace="false" data-dom-id="Pill-react-component-48a75bdd-425e-4c3a-ad04-cf2c3f00b790"></div> <div id="Pill-react-component-48a75bdd-425e-4c3a-ad04-cf2c3f00b790"></div> </a><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="36993140" href="https://www.academia.edu/Documents/in/Mass_Spectrometry"><div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Mass Spectrometry"]}" data-trace="false" data-dom-id="Pill-react-component-6630d80c-8ca0-4260-bbeb-4fdaac398845"></div> <div id="Pill-react-component-6630d80c-8ca0-4260-bbeb-4fdaac398845"></div> </a><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="36993140" href="https://www.academia.edu/Documents/in/Mathematics_and_Computer_Science"><div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Mathematics and Computer Science"]}" data-trace="false" data-dom-id="Pill-react-component-c1d9add6-c04c-438a-a9e7-179cad4ef400"></div> <div id="Pill-react-component-c1d9add6-c04c-438a-a9e7-179cad4ef400"></div> </a><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="36993140" href="https://www.academia.edu/Documents/in/Sustainable_Construction"><div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Sustainable Construction"]}" data-trace="false" data-dom-id="Pill-react-component-3c9fa982-7c6f-4fcd-b9a2-072ab37b2b50"></div> <div id="Pill-react-component-3c9fa982-7c6f-4fcd-b9a2-072ab37b2b50"></div> </a><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="36993140" href="https://www.academia.edu/Documents/in/Clinical_Sciences"><div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Clinical Sciences"]}" data-trace="false" data-dom-id="Pill-react-component-1cb153ed-b798-48ef-8a2d-5b812e2f54ad"></div> <div id="Pill-react-component-1cb153ed-b798-48ef-8a2d-5b812e2f54ad"></div> </a></div></div></div></div><div class="right-panel-container"><div class="user-content-wrapper"><div class="uploads-container" id="social-redesign-work-container"><div class="upload-header"><h2 class="ds2-5-heading-sans-serif-xs">Uploads</h2></div><div class="documents-container backbone-social-profile-documents" style="width: 100%;"><div class="u-taCenter"></div><div class="profile--tab_content_container js-tab-pane tab-pane active" id="all"><div class="profile--tab_heading_container js-section-heading" data-section="Papers" id="Papers"><h3 class="profile--tab_heading_container">Papers by Nicola Sannolo</h3></div><div class="js-work-strip profile--work_container" data-work-id="21133190"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/21133190/Study_of_interaction_of_styrene_oxide_with_Angiotensin_by_mass_spectrometry"><img alt="Research paper thumbnail of Study of interaction of styrene oxide with Angiotensin by mass spectrometry" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/21133190/Study_of_interaction_of_styrene_oxide_with_Angiotensin_by_mass_spectrometry">Study of interaction of styrene oxide with Angiotensin by mass spectrometry</a></div><div class="wp-workCard_item"><span>Carcinogenesis</span><span>, 1992</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The present study describes how mass spectrometry was extensively applied to the characterization...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The present study describes how mass spectrometry was extensively applied to the characterization and quantification of modified amino acids within the polypeptide chain of Angiotensin I, chosen as model substrate, combining the use of fast atom bombardment mass spectrometry with gas chromatography--mass spectrometry. The reaction products after in vitro incubation of Angiotensin I with styrene oxide, a well known carcinogen, under different conditions, have been characterized: a prominent reactivity of several potential nucleophilic sites of Angiotensin I was shown, including two histidine residues and a tyrosine residue; it is worth noting that it has never been stated that tyrosine is highly reactive with styrene oxide. The results obtained demonstrate the usefulness of mass spectrometry for the structural determination of chemically modified amino acids in peptides and proteins, and the presence of a reliable relationship between reaction conditions and the production of alkylated amino acids. This characterization procedure offers the possibility of identifying reactive sites following exposure to unknown alkylating agents.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="21133190"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="21133190"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 21133190; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=21133190]").text(description); $(".js-view-count[data-work-id=21133190]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 21133190; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='21133190']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 21133190, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=21133190]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":21133190,"title":"Study of interaction of styrene oxide with Angiotensin by mass spectrometry","translated_title":"","metadata":{"abstract":"The present study describes how mass spectrometry was extensively applied to the characterization and quantification of modified amino acids within the polypeptide chain of Angiotensin I, chosen as model substrate, combining the use of fast atom bombardment mass spectrometry with gas chromatography--mass spectrometry. The reaction products after in vitro incubation of Angiotensin I with styrene oxide, a well known carcinogen, under different conditions, have been characterized: a prominent reactivity of several potential nucleophilic sites of Angiotensin I was shown, including two histidine residues and a tyrosine residue; it is worth noting that it has never been stated that tyrosine is highly reactive with styrene oxide. The results obtained demonstrate the usefulness of mass spectrometry for the structural determination of chemically modified amino acids in peptides and proteins, and the presence of a reliable relationship between reaction conditions and the production of alkylated amino acids. This characterization procedure offers the possibility of identifying reactive sites following exposure to unknown alkylating agents.","publication_date":{"day":null,"month":null,"year":1992,"errors":{}},"publication_name":"Carcinogenesis"},"translated_abstract":"The present study describes how mass spectrometry was extensively applied to the characterization and quantification of modified amino acids within the polypeptide chain of Angiotensin I, chosen as model substrate, combining the use of fast atom bombardment mass spectrometry with gas chromatography--mass spectrometry. The reaction products after in vitro incubation of Angiotensin I with styrene oxide, a well known carcinogen, under different conditions, have been characterized: a prominent reactivity of several potential nucleophilic sites of Angiotensin I was shown, including two histidine residues and a tyrosine residue; it is worth noting that it has never been stated that tyrosine is highly reactive with styrene oxide. The results obtained demonstrate the usefulness of mass spectrometry for the structural determination of chemically modified amino acids in peptides and proteins, and the presence of a reliable relationship between reaction conditions and the production of alkylated amino acids. This characterization procedure offers the possibility of identifying reactive sites following exposure to unknown alkylating agents.","internal_url":"https://www.academia.edu/21133190/Study_of_interaction_of_styrene_oxide_with_Angiotensin_by_mass_spectrometry","translated_internal_url":"","created_at":"2016-01-29T06:10:59.282-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Study_of_interaction_of_styrene_oxide_with_Angiotensin_by_mass_spectrometry","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":5769,"name":"Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Mass_Spectrometry"},{"id":166448,"name":"Gas Chromatography","url":"https://www.academia.edu/Documents/in/Gas_Chromatography"},{"id":246560,"name":"High Pressure Liquid Chromatography","url":"https://www.academia.edu/Documents/in/High_Pressure_Liquid_Chromatography"},{"id":340262,"name":"Carcinogenesis","url":"https://www.academia.edu/Documents/in/Carcinogenesis"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="1326593"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/1326593/A_novel_approach_for_identification_and_measurement_of_hemoglobin_adducts_with_1_2_3_4_diepoxybutane_by_liquid_chromatography_electrospray_ionisation_mass_"><img alt="Research paper thumbnail of A novel approach for identification and measurement of hemoglobin adducts with 1, 2, 3, 4‐diepoxybutane by liquid chromatography/electrospray ionisation mass …" class="work-thumbnail" src="https://attachments.academia-assets.com/51026864/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/1326593/A_novel_approach_for_identification_and_measurement_of_hemoglobin_adducts_with_1_2_3_4_diepoxybutane_by_liquid_chromatography_electrospray_ionisation_mass_">A novel approach for identification and measurement of hemoglobin adducts with 1, 2, 3, 4‐diepoxybutane by liquid chromatography/electrospray ionisation mass …</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://unina2.academia.edu/NicolaSannolo">Nicola Sannolo</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://unina.academia.edu/AntonioMalorni">Antonio Malorni</a></span></div><div class="wp-workCard_item"><span>Rapid …</span><span>, Jan 1, 2001</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="9b7da16d6728292d4e2fd40ebfcd7fe5" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":51026864,"asset_id":1326593,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/51026864/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="1326593"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="1326593"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 1326593; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=1326593]").text(description); $(".js-view-count[data-work-id=1326593]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 1326593; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='1326593']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 1326593, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "9b7da16d6728292d4e2fd40ebfcd7fe5" } } $('.js-work-strip[data-work-id=1326593]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":1326593,"title":"A novel approach for identification and measurement of hemoglobin adducts with 1, 2, 3, 4‐diepoxybutane by liquid chromatography/electrospray ionisation mass …","translated_title":"","metadata":{"publisher":"Wiley Online Library","grobid_abstract":"The metabolic pathway of BD leads to the sequential formation of BMO, DEB and BDO-diol , and therefore in vivo several different covalent Hb-adducts can be","publication_date":{"day":1,"month":1,"year":2001,"errors":{}},"publication_name":"Rapid …","grobid_abstract_attachment_id":51026864},"translated_abstract":null,"internal_url":"https://www.academia.edu/1326593/A_novel_approach_for_identification_and_measurement_of_hemoglobin_adducts_with_1_2_3_4_diepoxybutane_by_liquid_chromatography_electrospray_ionisation_mass_","translated_internal_url":"","created_at":"2012-02-01T17:24:34.205-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":455266,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":13005039,"work_id":1326593,"tagging_user_id":455266,"tagged_user_id":36993140,"co_author_invite_id":null,"email":"n***o@unina2.it","affiliation":"Università della Campania Luigi Vanvitelli","display_order":0,"name":"Nicola Sannolo","title":"A novel approach for identification and measurement of hemoglobin adducts with 1, 2, 3, 4‐diepoxybutane by liquid chromatography/electrospray ionisation mass …"},{"id":13126959,"work_id":1326593,"tagging_user_id":455266,"tagged_user_id":289263208,"co_author_invite_id":1318798,"email":"f***i@unina.it","display_order":4194304,"name":"Pasquale Ferranti","title":"A novel approach for identification and measurement of hemoglobin adducts with 1, 2, 3, 4‐diepoxybutane by liquid chromatography/electrospray ionisation mass …"},{"id":13126960,"work_id":1326593,"tagging_user_id":455266,"tagged_user_id":36754615,"co_author_invite_id":null,"email":"l***o@uniba.it","display_order":6291456,"name":"Leonardo Soleo","title":"A novel approach for identification and measurement of hemoglobin adducts with 1, 2, 3, 4‐diepoxybutane by liquid chromatography/electrospray ionisation mass …"},{"id":13126961,"work_id":1326593,"tagging_user_id":455266,"tagged_user_id":44465197,"co_author_invite_id":1505964,"email":"c***a@unina.it","display_order":7340032,"name":"Simonetta Caira","title":"A novel approach for identification and measurement of hemoglobin adducts with 1, 2, 3, 4‐diepoxybutane by liquid chromatography/electrospray ionisation mass …"},{"id":18133370,"work_id":1326593,"tagging_user_id":455266,"tagged_user_id":37198082,"co_author_invite_id":null,"email":"n***a@unina2.it","display_order":7864320,"name":"N. Miraglia","title":"A novel approach for identification and measurement of hemoglobin adducts with 1, 2, 3, 4‐diepoxybutane by liquid chromatography/electrospray ionisation mass …"},{"id":18133478,"work_id":1326593,"tagging_user_id":455266,"tagged_user_id":41164279,"co_author_invite_id":null,"email":"m***e@isa.cnr.it","display_order":8126464,"name":"Gianfranco Mamone","title":"A novel approach for identification and measurement of hemoglobin adducts with 1, 2, 3, 4‐diepoxybutane by liquid chromatography/electrospray ionisation mass …"},{"id":18133489,"work_id":1326593,"tagging_user_id":455266,"tagged_user_id":null,"co_author_invite_id":1787103,"email":"g***i@isa.cnr.it","display_order":8257536,"name":"Gabriella Pocsfalvi","title":"A novel approach for identification and measurement of hemoglobin adducts with 1, 2, 3, 4‐diepoxybutane by liquid chromatography/electrospray ionisation mass …"}],"downloadable_attachments":[{"id":51026864,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/51026864/thumbnails/1.jpg","file_name":"rcm.26320161223-16399-5d0wea.pdf","download_url":"https://www.academia.edu/attachments/51026864/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"A_novel_approach_for_identification_and.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/51026864/rcm.26320161223-16399-5d0wea-libre.pdf?1482485555=\u0026response-content-disposition=attachment%3B+filename%3DA_novel_approach_for_identification_and.pdf\u0026Expires=1732833882\u0026Signature=hRhNMDSAB3gVnTWJgxnAJgGoAvpeRWvGhnDUCjempC3AEYmbaOkRks~qJ3qOEzRZOB2-xG~Tk-MlbihG8tzqi4xC1OORal98RxtMi9HNTkw1MXJMMMt-NGqLVwGoVSMPVCk432~VjcR8xJgeXHx~udzUsiCwrPw9u5z5WI0ASKlcuMMETIX44LebwGzcVaosdPCY-ea4~ewNBSkW5D2xdc08qHG2F94jsqFJEmg0-GpXQ7sE1ttvCxzJPyPq9qr93fBIAVNGxendxP3Sc8RstMfgY9if2~HyShgNSQZuwNq1gNeeSDK2kXVV2MtU379GQuCEHT3XiyU3wAKfyPNAeA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"A_novel_approach_for_identification_and_measurement_of_hemoglobin_adducts_with_1_2_3_4_diepoxybutane_by_liquid_chromatography_electrospray_ionisation_mass_","translated_slug":"","page_count":14,"language":"en","content_type":"Work","owner":{"id":455266,"first_name":"Antonio","middle_initials":null,"last_name":"Malorni","page_name":"AntonioMalorni","domain_name":"unina","created_at":"2011-05-26T04:11:01.121-07:00","display_name":"Antonio Malorni","url":"https://unina.academia.edu/AntonioMalorni"},"attachments":[{"id":51026864,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/51026864/thumbnails/1.jpg","file_name":"rcm.26320161223-16399-5d0wea.pdf","download_url":"https://www.academia.edu/attachments/51026864/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"A_novel_approach_for_identification_and.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/51026864/rcm.26320161223-16399-5d0wea-libre.pdf?1482485555=\u0026response-content-disposition=attachment%3B+filename%3DA_novel_approach_for_identification_and.pdf\u0026Expires=1732833882\u0026Signature=hRhNMDSAB3gVnTWJgxnAJgGoAvpeRWvGhnDUCjempC3AEYmbaOkRks~qJ3qOEzRZOB2-xG~Tk-MlbihG8tzqi4xC1OORal98RxtMi9HNTkw1MXJMMMt-NGqLVwGoVSMPVCk432~VjcR8xJgeXHx~udzUsiCwrPw9u5z5WI0ASKlcuMMETIX44LebwGzcVaosdPCY-ea4~ewNBSkW5D2xdc08qHG2F94jsqFJEmg0-GpXQ7sE1ttvCxzJPyPq9qr93fBIAVNGxendxP3Sc8RstMfgY9if2~HyShgNSQZuwNq1gNeeSDK2kXVV2MtU379GQuCEHT3XiyU3wAKfyPNAeA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":400,"name":"Earth Sciences","url":"https://www.academia.edu/Documents/in/Earth_Sciences"},{"id":5769,"name":"Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Mass_Spectrometry"},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences"},{"id":151086,"name":"Peptides","url":"https://www.academia.edu/Documents/in/Peptides"},{"id":163275,"name":"Tandem Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Tandem_Mass_Spectrometry"},{"id":167158,"name":"Trypsin","url":"https://www.academia.edu/Documents/in/Trypsin"},{"id":246560,"name":"High Pressure Liquid Chromatography","url":"https://www.academia.edu/Documents/in/High_Pressure_Liquid_Chromatography"},{"id":260118,"name":"CHEMICAL SCIENCES","url":"https://www.academia.edu/Documents/in/CHEMICAL_SCIENCES"},{"id":326380,"name":"Liquid Chromatography / Electrospray Ionization Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Liquid_Chromatography_Electrospray_Ionization_Mass_Spectrometry"},{"id":398287,"name":"Liquid Chromatography","url":"https://www.academia.edu/Documents/in/Liquid_Chromatography"},{"id":664186,"name":"Alkylation","url":"https://www.academia.edu/Documents/in/Alkylation"},{"id":1311261,"name":"Hemoglobins","url":"https://www.academia.edu/Documents/in/Hemoglobins"},{"id":1485193,"name":"Rapid","url":"https://www.academia.edu/Documents/in/Rapid"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17402706"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17402706/Interaction_between_combustion_generated_organic_nanoparticles_and_biological_systems_In_vitro_study_of_cell_toxicity_and_apoptosis_in_human_keratinocytes"><img alt="Research paper thumbnail of Interaction between combustion-generated organic nanoparticles and biological systems: In vitro study of cell toxicity and apoptosis in human keratinocytes" class="work-thumbnail" src="https://attachments.academia-assets.com/39487935/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17402706/Interaction_between_combustion_generated_organic_nanoparticles_and_biological_systems_In_vitro_study_of_cell_toxicity_and_apoptosis_in_human_keratinocytes">Interaction between combustion-generated organic nanoparticles and biological systems: In vitro study of cell toxicity and apoptosis in human keratinocytes</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/PaolaPedata">Paola Pedata</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/patriziaminutolo">patrizia minutolo</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://unina2.academia.edu/NicolaSannolo">Nicola Sannolo</a></span></div><div class="wp-workCard_item"><span>Nanotoxicology</span><span>, 2012</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="42fb2877d28c694637524f5fd051e17b" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":39487935,"asset_id":17402706,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/39487935/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17402706"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17402706"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17402706; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17402706]").text(description); $(".js-view-count[data-work-id=17402706]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17402706; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17402706']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17402706, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "42fb2877d28c694637524f5fd051e17b" } } $('.js-work-strip[data-work-id=17402706]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17402706,"title":"Interaction between combustion-generated organic nanoparticles and biological systems: In vitro study of cell toxicity and apoptosis in human keratinocytes","translated_title":"","metadata":{"publication_date":{"day":null,"month":null,"year":2012,"errors":{}},"publication_name":"Nanotoxicology"},"translated_abstract":null,"internal_url":"https://www.academia.edu/17402706/Interaction_between_combustion_generated_organic_nanoparticles_and_biological_systems_In_vitro_study_of_cell_toxicity_and_apoptosis_in_human_keratinocytes","translated_internal_url":"","created_at":"2015-10-28T02:29:10.099-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":37126197,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":8131153,"work_id":17402706,"tagging_user_id":37126197,"tagged_user_id":38332080,"co_author_invite_id":444112,"email":"p***f@unina.it","display_order":0,"name":"Raffaele Porta","title":"Interaction between combustion-generated organic nanoparticles and biological systems: In vitro study of cell toxicity and apoptosis in human keratinocytes"},{"id":8131159,"work_id":17402706,"tagging_user_id":37126197,"tagged_user_id":31501796,"co_author_invite_id":1816707,"email":"p***8@gmail.com","display_order":4194304,"name":"patrizia minutolo","title":"Interaction between combustion-generated organic nanoparticles and biological systems: In vitro study of cell toxicity and apoptosis in human keratinocytes"},{"id":8131161,"work_id":17402706,"tagging_user_id":37126197,"tagged_user_id":null,"co_author_invite_id":1816709,"email":"m***o@st.com","display_order":6291456,"name":"Maria Napolitano","title":"Interaction between combustion-generated organic nanoparticles and biological systems: In vitro study of cell toxicity and apoptosis in human keratinocytes"},{"id":8131162,"work_id":17402706,"tagging_user_id":37126197,"tagged_user_id":null,"co_author_invite_id":1816710,"email":"l***o@yahoo.com","display_order":7340032,"name":"Lee Sgro","title":"Interaction between combustion-generated organic nanoparticles and biological systems: In vitro study of cell toxicity and apoptosis in human keratinocytes"},{"id":8131166,"work_id":17402706,"tagging_user_id":37126197,"tagged_user_id":36993140,"co_author_invite_id":null,"email":"n***o@unina2.it","affiliation":"Università della Campania Luigi Vanvitelli","display_order":7864320,"name":"Nicola Sannolo","title":"Interaction between combustion-generated organic nanoparticles and biological systems: In vitro study of cell toxicity and apoptosis in human keratinocytes"}],"downloadable_attachments":[{"id":39487935,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39487935/thumbnails/1.jpg","file_name":"Interaction_between_combustion-generated20151028-28426-1s6lzcw.pdf","download_url":"https://www.academia.edu/attachments/39487935/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Interaction_between_combustion_generated.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39487935/Interaction_between_combustion-generated20151028-28426-1s6lzcw-libre.pdf?1446032657=\u0026response-content-disposition=attachment%3B+filename%3DInteraction_between_combustion_generated.pdf\u0026Expires=1732833882\u0026Signature=RHgTEbOAtOAzKP-25-73gaETaKq90hmEgkkyK-LOuhXp71yu~Irn6WXVZ39novZwOgKqampzB8JD~Uet3J34m2yelbMK8Ch2nra556muGFd5Ob0BQBsOlr4ij~WNi7b~h5yZ7ZVIvbbcwnS2KBl~4jWfNlFeqMTzt09FO~qog2JK2G621QQ2r0i02pJQJBDCkFsuTwEOopJtFKZopTmHyR2AG~-Cvd925OYYseQpKoN3gZOFVeLSAQblQzljjlHdrv0pnPJkgX3NWG35QtSt0Au0FJnBoo0vDY3bmaQSImx08OT4GvpLRxT658SGUbWMSsENfvO~8NVW8d55LSiyvw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Interaction_between_combustion_generated_organic_nanoparticles_and_biological_systems_In_vitro_study_of_cell_toxicity_and_apoptosis_in_human_keratinocytes","translated_slug":"","page_count":18,"language":"en","content_type":"Work","owner":{"id":37126197,"first_name":"Paola","middle_initials":null,"last_name":"Pedata","page_name":"PaolaPedata","domain_name":"independent","created_at":"2015-10-28T02:28:26.614-07:00","display_name":"Paola Pedata","url":"https://independent.academia.edu/PaolaPedata"},"attachments":[{"id":39487935,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39487935/thumbnails/1.jpg","file_name":"Interaction_between_combustion-generated20151028-28426-1s6lzcw.pdf","download_url":"https://www.academia.edu/attachments/39487935/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Interaction_between_combustion_generated.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39487935/Interaction_between_combustion-generated20151028-28426-1s6lzcw-libre.pdf?1446032657=\u0026response-content-disposition=attachment%3B+filename%3DInteraction_between_combustion_generated.pdf\u0026Expires=1732833882\u0026Signature=RHgTEbOAtOAzKP-25-73gaETaKq90hmEgkkyK-LOuhXp71yu~Irn6WXVZ39novZwOgKqampzB8JD~Uet3J34m2yelbMK8Ch2nra556muGFd5Ob0BQBsOlr4ij~WNi7b~h5yZ7ZVIvbbcwnS2KBl~4jWfNlFeqMTzt09FO~qog2JK2G621QQ2r0i02pJQJBDCkFsuTwEOopJtFKZopTmHyR2AG~-Cvd925OYYseQpKoN3gZOFVeLSAQblQzljjlHdrv0pnPJkgX3NWG35QtSt0Au0FJnBoo0vDY3bmaQSImx08OT4GvpLRxT658SGUbWMSsENfvO~8NVW8d55LSiyvw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":5303,"name":"Carbon","url":"https://www.academia.edu/Documents/in/Carbon"},{"id":13621,"name":"Nanoparticles","url":"https://www.academia.edu/Documents/in/Nanoparticles"},{"id":17733,"name":"Nanotechnology","url":"https://www.academia.edu/Documents/in/Nanotechnology"},{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis"},{"id":47402,"name":"Nanotoxicology","url":"https://www.academia.edu/Documents/in/Nanotoxicology"},{"id":48057,"name":"DNA","url":"https://www.academia.edu/Documents/in/DNA"},{"id":57808,"name":"Cell line","url":"https://www.academia.edu/Documents/in/Cell_line"},{"id":70552,"name":"Keratinocytes","url":"https://www.academia.edu/Documents/in/Keratinocytes"},{"id":518609,"name":"Particulate Matter","url":"https://www.academia.edu/Documents/in/Particulate_Matter"},{"id":666927,"name":"Toxicity Tests","url":"https://www.academia.edu/Documents/in/Toxicity_Tests"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17402705"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17402705/Epirubicin_permeation_of_personal_protective_equipment_can_induce_apoptosis_in_keratinocytes"><img alt="Research paper thumbnail of Epirubicin permeation of personal protective equipment can induce apoptosis in keratinocytes" class="work-thumbnail" src="https://attachments.academia-assets.com/39487981/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17402705/Epirubicin_permeation_of_personal_protective_equipment_can_induce_apoptosis_in_keratinocytes">Epirubicin permeation of personal protective equipment can induce apoptosis in keratinocytes</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/PaolaPedata">Paola Pedata</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://unina2.academia.edu/NicolaSannolo">Nicola Sannolo</a></span></div><div class="wp-workCard_item"><span>Journal of Exposure Science and Environmental Epidemiology</span><span>, 2012</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="14933f0c8a396490711541bccd385ac0" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":39487981,"asset_id":17402705,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/39487981/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17402705"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17402705"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17402705; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17402705]").text(description); $(".js-view-count[data-work-id=17402705]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17402705; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17402705']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17402705, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "14933f0c8a396490711541bccd385ac0" } } $('.js-work-strip[data-work-id=17402705]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17402705,"title":"Epirubicin permeation of personal protective equipment can induce apoptosis in keratinocytes","translated_title":"","metadata":{"grobid_abstract":"The present study investigated the epirubicin (EPI) permeability of various commercially available glove types, as well as toxicity mechanisms and effects on human keratinocyte cell line (HaCaT). Permeability experiments were carried out on various commercially available gloves, differing as regards material and thickness. Permeability was evaluated after different ''contact times'' and the influence of EPI solution's pH (acid and neutral) on permeability was also examined. Toxicity of EPI toward skin was tested by evaluating the effects of the drug on cell growth and apoptosis, by using an in vitro model based on cultured immortalized human keratinocytes. No permeation was detected in the case of EPI neutral solutions; in contrast, acid solutions were found to penetrate low thickness nitrile gloves. Obtained results also showed the induction of apoptosis in epithelial cells through the activation of intrinsic pathway p53-independent occurring even when cells are exposed at low drug concentration. EPI solution's pH influences the glove's permeability; once penetrated, EPI at concentrations lower than those able to penetrate the nitrile glove during the 8-h work-shift can cause apoptosis in epithelial cells. The findings reported here highly support the choice of either natural rubbers gloves or high thickness nitrile ones for preventing the occupational exposure to EPI Q2 .","publication_date":{"day":null,"month":null,"year":2012,"errors":{}},"publication_name":"Journal of Exposure Science and Environmental Epidemiology","grobid_abstract_attachment_id":39487981},"translated_abstract":null,"internal_url":"https://www.academia.edu/17402705/Epirubicin_permeation_of_personal_protective_equipment_can_induce_apoptosis_in_keratinocytes","translated_internal_url":"","created_at":"2015-10-28T02:29:09.989-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":37126197,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":8131137,"work_id":17402705,"tagging_user_id":37126197,"tagged_user_id":37198082,"co_author_invite_id":1787097,"email":"n***a@unina2.it","display_order":0,"name":"N. Miraglia","title":"Epirubicin permeation of personal protective equipment can induce apoptosis in keratinocytes"},{"id":8131142,"work_id":17402705,"tagging_user_id":37126197,"tagged_user_id":64980285,"co_author_invite_id":1816700,"email":"m***i@unifi.it","display_order":4194304,"name":"Maria Pace Pieri","title":"Epirubicin permeation of personal protective equipment can induce apoptosis in keratinocytes"},{"id":8131152,"work_id":17402705,"tagging_user_id":37126197,"tagged_user_id":38332080,"co_author_invite_id":444112,"email":"p***f@unina.it","display_order":6291456,"name":"Raffaele Porta","title":"Epirubicin permeation of personal protective equipment can induce apoptosis in keratinocytes"},{"id":8131154,"work_id":17402705,"tagging_user_id":37126197,"tagged_user_id":null,"co_author_invite_id":1816705,"email":"a***e@iade.pt","display_order":7340032,"name":"Angela Silvestre","title":"Epirubicin permeation of personal protective equipment can induce apoptosis in keratinocytes"},{"id":8131156,"work_id":17402705,"tagging_user_id":37126197,"tagged_user_id":37456612,"co_author_invite_id":1816706,"email":"a***a@unina.it","display_order":7864320,"name":"Antonio Acampora","title":"Epirubicin permeation of personal protective equipment can induce apoptosis in keratinocytes"},{"id":8131165,"work_id":17402705,"tagging_user_id":37126197,"tagged_user_id":36993140,"co_author_invite_id":null,"email":"n***o@unina2.it","affiliation":"Università della Campania Luigi Vanvitelli","display_order":8126464,"name":"Nicola Sannolo","title":"Epirubicin permeation of personal protective equipment can induce apoptosis in keratinocytes"}],"downloadable_attachments":[{"id":39487981,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39487981/thumbnails/1.jpg","file_name":"Epirubicin_permeation_of_personal_protec20151028-22222-1od0mkr.pdf","download_url":"https://www.academia.edu/attachments/39487981/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Epirubicin_permeation_of_personal_protec.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39487981/Epirubicin_permeation_of_personal_protec20151028-22222-1od0mkr-libre.pdf?1446032918=\u0026response-content-disposition=attachment%3B+filename%3DEpirubicin_permeation_of_personal_protec.pdf\u0026Expires=1732833882\u0026Signature=P43crSCB6gY3-HpIGSp-uu2N4DdCK7TCQf50Eq2y58Mf13b9FPOT1VGMoTfZ~3svEEVwbJ5RKYs9FzIWVsrX6sMErfvV4EKQj1yfR6xh1bMT88pgI5nXOPm8zT60SeT5Ai5rWZ-MvEOEtS2uka5qoIOw39CBGfHp7uTppGsVggrDq-3VoS-DGFeEDoGJTfO-f2Wc9ZFrKvsBbOq74eKHKHUGyyR7DhP9ML17tkpPwWhmjkfbc5rOK1UWtUC1TPv7OyCjm9b06qIuV94Xm-kAEvfWaQ9q~m~DNN8bRUujF5-378R~BHUjbZjKUMh-WeT3Lc2hpPSSm1dnKCfwCF04yw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Epirubicin_permeation_of_personal_protective_equipment_can_induce_apoptosis_in_keratinocytes","translated_slug":"","page_count":7,"language":"en","content_type":"Work","owner":{"id":37126197,"first_name":"Paola","middle_initials":null,"last_name":"Pedata","page_name":"PaolaPedata","domain_name":"independent","created_at":"2015-10-28T02:28:26.614-07:00","display_name":"Paola Pedata","url":"https://independent.academia.edu/PaolaPedata"},"attachments":[{"id":39487981,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39487981/thumbnails/1.jpg","file_name":"Epirubicin_permeation_of_personal_protec20151028-22222-1od0mkr.pdf","download_url":"https://www.academia.edu/attachments/39487981/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Epirubicin_permeation_of_personal_protec.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39487981/Epirubicin_permeation_of_personal_protec20151028-22222-1od0mkr-libre.pdf?1446032918=\u0026response-content-disposition=attachment%3B+filename%3DEpirubicin_permeation_of_personal_protec.pdf\u0026Expires=1732833882\u0026Signature=P43crSCB6gY3-HpIGSp-uu2N4DdCK7TCQf50Eq2y58Mf13b9FPOT1VGMoTfZ~3svEEVwbJ5RKYs9FzIWVsrX6sMErfvV4EKQj1yfR6xh1bMT88pgI5nXOPm8zT60SeT5Ai5rWZ-MvEOEtS2uka5qoIOw39CBGfHp7uTppGsVggrDq-3VoS-DGFeEDoGJTfO-f2Wc9ZFrKvsBbOq74eKHKHUGyyR7DhP9ML17tkpPwWhmjkfbc5rOK1UWtUC1TPv7OyCjm9b06qIuV94Xm-kAEvfWaQ9q~m~DNN8bRUujF5-378R~BHUjbZjKUMh-WeT3Lc2hpPSSm1dnKCfwCF04yw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis"},{"id":37834,"name":"Western blotting","url":"https://www.academia.edu/Documents/in/Western_blotting"},{"id":50841,"name":"Caspases","url":"https://www.academia.edu/Documents/in/Caspases"},{"id":57808,"name":"Cell line","url":"https://www.academia.edu/Documents/in/Cell_line"},{"id":58054,"name":"Environmental Sciences","url":"https://www.academia.edu/Documents/in/Environmental_Sciences"},{"id":70552,"name":"Keratinocytes","url":"https://www.academia.edu/Documents/in/Keratinocytes"},{"id":83972,"name":"Permeability","url":"https://www.academia.edu/Documents/in/Permeability"},{"id":260118,"name":"CHEMICAL SCIENCES","url":"https://www.academia.edu/Documents/in/CHEMICAL_SCIENCES"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17401919"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17401919/_Absorption_distribution_and_elimination_of_carbon_monoxide_"><img alt="Research paper thumbnail of [Absorption, distribution and elimination of carbon monoxide]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17401919/_Absorption_distribution_and_elimination_of_carbon_monoxide_">[Absorption, distribution and elimination of carbon monoxide]</a></div><div class="wp-workCard_item"><span>Archivio Monaldi per le malattie del torace</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17401919"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17401919"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17401919; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17401919]").text(description); $(".js-view-count[data-work-id=17401919]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17401919; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17401919']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17401919, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17401919]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17401919,"title":"[Absorption, distribution and elimination of carbon monoxide]","translated_title":"","metadata":{"publication_name":"Archivio Monaldi per le malattie del torace"},"translated_abstract":null,"internal_url":"https://www.academia.edu/17401919/_Absorption_distribution_and_elimination_of_carbon_monoxide_","translated_internal_url":"","created_at":"2015-10-28T02:14:15.550-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"_Absorption_distribution_and_elimination_of_carbon_monoxide_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":11801,"name":"Environmental Monitoring","url":"https://www.academia.edu/Documents/in/Environmental_Monitoring"},{"id":71905,"name":"Carbon Monoxide","url":"https://www.academia.edu/Documents/in/Carbon_Monoxide"},{"id":396914,"name":"Occupational Exposure","url":"https://www.academia.edu/Documents/in/Occupational_Exposure"},{"id":1311261,"name":"Hemoglobins","url":"https://www.academia.edu/Documents/in/Hemoglobins"},{"id":1341982,"name":"Carbon Monoxide Poisoning","url":"https://www.academia.edu/Documents/in/Carbon_Monoxide_Poisoning"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17401918"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/17401918/_Methods_of_screening_for_cystinuria_Proposed_use_of_thin_layer_chromatography_"><img alt="Research paper thumbnail of [Methods of screening for cystinuria. Proposed use of thin-layer chromatography]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/17401918/_Methods_of_screening_for_cystinuria_Proposed_use_of_thin_layer_chromatography_">[Methods of screening for cystinuria. Proposed use of thin-layer chromatography]</a></div><div class="wp-workCard_item"><span>La Pediatria</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17401918"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17401918"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17401918; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17401918]").text(description); $(".js-view-count[data-work-id=17401918]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17401918; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17401918']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17401918, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17401918]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17401918,"title":"[Methods of screening for cystinuria. Proposed use of thin-layer chromatography]","translated_title":"","metadata":{"publication_name":"La Pediatria"},"translated_abstract":null,"internal_url":"https://www.academia.edu/17401918/_Methods_of_screening_for_cystinuria_Proposed_use_of_thin_layer_chromatography_","translated_internal_url":"","created_at":"2015-10-28T02:14:15.426-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"_Methods_of_screening_for_cystinuria_Proposed_use_of_thin_layer_chromatography_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":295928,"name":"Amino Acids","url":"https://www.academia.edu/Documents/in/Amino_Acids"},{"id":888739,"name":"Quntitative Thin Layer Chromatography","url":"https://www.academia.edu/Documents/in/Quntitative_Thin_Layer_Chromatography"},{"id":1438730,"name":"Creatinine","url":"https://www.academia.edu/Documents/in/Creatinine"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17401917"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17401917/Indicatori_di_dose_biologicamente_efficace"><img alt="Research paper thumbnail of Indicatori di dose biologicamente efficace" class="work-thumbnail" src="https://attachments.academia-assets.com/39487527/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17401917/Indicatori_di_dose_biologicamente_efficace">Indicatori di dose biologicamente efficace</a></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="0653fe4bd2adbc01ee31b6f583140cf8" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":39487527,"asset_id":17401917,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/39487527/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17401917"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17401917"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17401917; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17401917]").text(description); $(".js-view-count[data-work-id=17401917]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17401917; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17401917']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17401917, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "0653fe4bd2adbc01ee31b6f583140cf8" } } $('.js-work-strip[data-work-id=17401917]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17401917,"title":"Indicatori di dose biologicamente efficace","translated_title":"","metadata":{},"translated_abstract":null,"internal_url":"https://www.academia.edu/17401917/Indicatori_di_dose_biologicamente_efficace","translated_internal_url":"","created_at":"2015-10-28T02:14:15.315-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":39487527,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39487527/thumbnails/1.jpg","file_name":"Indicatori_di_dose_biologicamente_effica20151028-29725-1jooopq.pdf","download_url":"https://www.academia.edu/attachments/39487527/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Indicatori_di_dose_biologicamente_effica.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39487527/Indicatori_di_dose_biologicamente_effica20151028-29725-1jooopq-libre.pdf?1446032701=\u0026response-content-disposition=attachment%3B+filename%3DIndicatori_di_dose_biologicamente_effica.pdf\u0026Expires=1732833882\u0026Signature=TO-EkMvj-J7rjpoAkHw6TjfBSmUg8DVOb6x6Ejnw5xrdAd9SEyMJu9ELgZ4ZsqNkRumK5S8MJdnmkRxAYa9SwsweWXrsrdq4rW~ZGxTktJeq8ChQe3nDj4plBqi~YgY7duZ9D9uRQq7A4W9F07tzThID8hK5v4NEf052KSC6ro7o5Dh28lhqZ4Hq3SLbctySfC-4N3ptjtZOC8s2GbYpX6MP2mHjI6pvvimLMufUCyObzTxtxpK8EdZz9qSDhgIdCthhNpczo6fiiHzmJIfROuyBkXdaTYr1ChStWurKcSp77qDbycvjFbRz7aKcrbVkLNjg1BN-pgOPmARfK3GDeg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Indicatori_di_dose_biologicamente_efficace","translated_slug":"","page_count":4,"language":"it","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[{"id":39487527,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39487527/thumbnails/1.jpg","file_name":"Indicatori_di_dose_biologicamente_effica20151028-29725-1jooopq.pdf","download_url":"https://www.academia.edu/attachments/39487527/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Indicatori_di_dose_biologicamente_effica.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39487527/Indicatori_di_dose_biologicamente_effica20151028-29725-1jooopq-libre.pdf?1446032701=\u0026response-content-disposition=attachment%3B+filename%3DIndicatori_di_dose_biologicamente_effica.pdf\u0026Expires=1732833882\u0026Signature=TO-EkMvj-J7rjpoAkHw6TjfBSmUg8DVOb6x6Ejnw5xrdAd9SEyMJu9ELgZ4ZsqNkRumK5S8MJdnmkRxAYa9SwsweWXrsrdq4rW~ZGxTktJeq8ChQe3nDj4plBqi~YgY7duZ9D9uRQq7A4W9F07tzThID8hK5v4NEf052KSC6ro7o5Dh28lhqZ4Hq3SLbctySfC-4N3ptjtZOC8s2GbYpX6MP2mHjI6pvvimLMufUCyObzTxtxpK8EdZz9qSDhgIdCthhNpczo6fiiHzmJIfROuyBkXdaTYr1ChStWurKcSp77qDbycvjFbRz7aKcrbVkLNjg1BN-pgOPmARfK3GDeg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17401916"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17401916/_Extraction_of_fecal_lipids_and_identification_of_hydroxystearic_acid_by_gas_chromatography_mass_spectrometry_GC_MS_"><img alt="Research paper thumbnail of [Extraction of fecal lipids and identification of hydroxystearic acid by gas chromatography-mass spectrometry (GC/MS)]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17401916/_Extraction_of_fecal_lipids_and_identification_of_hydroxystearic_acid_by_gas_chromatography_mass_spectrometry_GC_MS_">[Extraction of fecal lipids and identification of hydroxystearic acid by gas chromatography-mass spectrometry (GC/MS)]</a></div><div class="wp-workCard_item"><span>Bollettino della Società italiana di biologia sperimentale</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Fatty acids and hydroxy fatty acids in the intestine are of interest because of their cathartic p...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Fatty acids and hydroxy fatty acids in the intestine are of interest because of their cathartic properties. We describe a method for extraction of lipids from freeze dried homogenized stools and identification of the hydroxy stearic acid in the fecal lipids pattern by GC-MS. Recovery of 90-95 % shows the efficacy of extraction . Quantitative data of fecal hydroxy stearic acid excretion in some normal and chronic diarrhea affected children are reported.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17401916"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17401916"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17401916; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17401916]").text(description); $(".js-view-count[data-work-id=17401916]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17401916; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17401916']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17401916, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17401916]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17401916,"title":"[Extraction of fecal lipids and identification of hydroxystearic acid by gas chromatography-mass spectrometry (GC/MS)]","translated_title":"","metadata":{"abstract":"Fatty acids and hydroxy fatty acids in the intestine are of interest because of their cathartic properties. We describe a method for extraction of lipids from freeze dried homogenized stools and identification of the hydroxy stearic acid in the fecal lipids pattern by GC-MS. Recovery of 90-95 % shows the efficacy of extraction . Quantitative data of fecal hydroxy stearic acid excretion in some normal and chronic diarrhea affected children are reported.","publication_name":"Bollettino della Società italiana di biologia sperimentale"},"translated_abstract":"Fatty acids and hydroxy fatty acids in the intestine are of interest because of their cathartic properties. We describe a method for extraction of lipids from freeze dried homogenized stools and identification of the hydroxy stearic acid in the fecal lipids pattern by GC-MS. Recovery of 90-95 % shows the efficacy of extraction . Quantitative data of fecal hydroxy stearic acid excretion in some normal and chronic diarrhea affected children are reported.","internal_url":"https://www.academia.edu/17401916/_Extraction_of_fecal_lipids_and_identification_of_hydroxystearic_acid_by_gas_chromatography_mass_spectrometry_GC_MS_","translated_internal_url":"","created_at":"2015-10-28T02:14:15.205-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"_Extraction_of_fecal_lipids_and_identification_of_hydroxystearic_acid_by_gas_chromatography_mass_spectrometry_GC_MS_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":44259,"name":"Diarrhea","url":"https://www.academia.edu/Documents/in/Diarrhea"},{"id":52055,"name":"Lipids","url":"https://www.academia.edu/Documents/in/Lipids"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child"},{"id":97269,"name":"Chronic Disease","url":"https://www.academia.edu/Documents/in/Chronic_Disease"},{"id":469102,"name":"Feces","url":"https://www.academia.edu/Documents/in/Feces"},{"id":529560,"name":"Gas Chromatography/mass Spectrometry","url":"https://www.academia.edu/Documents/in/Gas_Chromatography_mass_Spectrometry"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17401915"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17401915/Gas_chromatographic_quantitation_of_breath_hydrogen_and_carbon_monoxide_for_clinical_investigation_in_adults_and_in_children"><img alt="Research paper thumbnail of Gas chromatographic quantitation of breath hydrogen and carbon monoxide for clinical investigation in adults and in children" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17401915/Gas_chromatographic_quantitation_of_breath_hydrogen_and_carbon_monoxide_for_clinical_investigation_in_adults_and_in_children">Gas chromatographic quantitation of breath hydrogen and carbon monoxide for clinical investigation in adults and in children</a></div><div class="wp-workCard_item"><span>Journal of chromatography</span><span>, Jan 9, 1983</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">A simple and suitable method of breath sampling and the gas chromatographic determination of H2 a...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">A simple and suitable method of breath sampling and the gas chromatographic determination of H2 and CO in breath of children as well as of adults are described. The analytical system allows the measurement of concentrations of H2 and CO as low as a few ppm. The proposed method of breath collection (tedlar bag with low resistance valve face mask) appears particularly useful for long storage purposes, because it eliminates the need for additional manipulations and the possible associated sample dilution. Normalization of H2 breath amounts to internal standard O2 to obtain reliable and precise measurements is particularly useful in non-collaborating patients whose observed H2 peak values increase by 15% after the correction. The overall procedure is fast, inexpensive and accurately recognizes adult or children lactose malabsorbers as well as subjects exposed even to low levels of CO.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17401915"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17401915"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17401915; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17401915]").text(description); $(".js-view-count[data-work-id=17401915]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17401915; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17401915']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17401915, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17401915]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17401915,"title":"Gas chromatographic quantitation of breath hydrogen and carbon monoxide for clinical investigation in adults and in children","translated_title":"","metadata":{"abstract":"A simple and suitable method of breath sampling and the gas chromatographic determination of H2 and CO in breath of children as well as of adults are described. The analytical system allows the measurement of concentrations of H2 and CO as low as a few ppm. The proposed method of breath collection (tedlar bag with low resistance valve face mask) appears particularly useful for long storage purposes, because it eliminates the need for additional manipulations and the possible associated sample dilution. Normalization of H2 breath amounts to internal standard O2 to obtain reliable and precise measurements is particularly useful in non-collaborating patients whose observed H2 peak values increase by 15% after the correction. The overall procedure is fast, inexpensive and accurately recognizes adult or children lactose malabsorbers as well as subjects exposed even to low levels of CO.","publication_date":{"day":9,"month":1,"year":1983,"errors":{}},"publication_name":"Journal of chromatography"},"translated_abstract":"A simple and suitable method of breath sampling and the gas chromatographic determination of H2 and CO in breath of children as well as of adults are described. The analytical system allows the measurement of concentrations of H2 and CO as low as a few ppm. The proposed method of breath collection (tedlar bag with low resistance valve face mask) appears particularly useful for long storage purposes, because it eliminates the need for additional manipulations and the possible associated sample dilution. Normalization of H2 breath amounts to internal standard O2 to obtain reliable and precise measurements is particularly useful in non-collaborating patients whose observed H2 peak values increase by 15% after the correction. The overall procedure is fast, inexpensive and accurately recognizes adult or children lactose malabsorbers as well as subjects exposed even to low levels of CO.","internal_url":"https://www.academia.edu/17401915/Gas_chromatographic_quantitation_of_breath_hydrogen_and_carbon_monoxide_for_clinical_investigation_in_adults_and_in_children","translated_internal_url":"","created_at":"2015-10-28T02:14:15.086-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Gas_chromatographic_quantitation_of_breath_hydrogen_and_carbon_monoxide_for_clinical_investigation_in_adults_and_in_children","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":48,"name":"Engineering","url":"https://www.academia.edu/Documents/in/Engineering"},{"id":923,"name":"Technology","url":"https://www.academia.edu/Documents/in/Technology"},{"id":3771,"name":"Hydrogen","url":"https://www.academia.edu/Documents/in/Hydrogen"},{"id":4656,"name":"Chromatography","url":"https://www.academia.edu/Documents/in/Chromatography"},{"id":6791,"name":"Aging","url":"https://www.academia.edu/Documents/in/Aging"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child"},{"id":71300,"name":"Blood Glucose","url":"https://www.academia.edu/Documents/in/Blood_Glucose"},{"id":71905,"name":"Carbon Monoxide","url":"https://www.academia.edu/Documents/in/Carbon_Monoxide"},{"id":75318,"name":"Smoking","url":"https://www.academia.edu/Documents/in/Smoking"},{"id":78534,"name":"Lactose intolerance","url":"https://www.academia.edu/Documents/in/Lactose_intolerance"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant"},{"id":166448,"name":"Gas Chromatography","url":"https://www.academia.edu/Documents/in/Gas_Chromatography"},{"id":260118,"name":"CHEMICAL SCIENCES","url":"https://www.academia.edu/Documents/in/CHEMICAL_SCIENCES"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17401914"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17401914/Mass_spectrometric_analysis_of_rat_hemoglobin_by_FAB_overlapping"><img alt="Research paper thumbnail of Mass spectrometric analysis of rat hemoglobin by FAB-overlapping" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17401914/Mass_spectrometric_analysis_of_rat_hemoglobin_by_FAB_overlapping">Mass spectrometric analysis of rat hemoglobin by FAB-overlapping</a></div><div class="wp-workCard_item"><span>International Journal of Biochemistry</span><span>, 1988</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">1. The globin chain components of Sprague-Dawley rat hemoglobin were obtained by reverse-phase HP...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">1. The globin chain components of Sprague-Dawley rat hemoglobin were obtained by reverse-phase HPLC which showed the presence of two alpha-chain and four beta-chains. 2. The accurate molecular weight of each globin chain was determined by means of electrospray mass spectrometry. Extensive mass spectrometric analysis on several enzymatic digests by fast atom bombardment mass spectrometry (FAB-overlapping) meant to determine the complete sequence of the alpha-major and of the four beta-globins. 3. The primary structure of the alpha-major globin was found in agreement with literature data (Garrick et al., 1975 Biochem. J. 149, 245-258; Chua et al., 1987). 4. Sequence analysis of the four beta-globin chains showed that amino acid differences are restricted to two protein portions: the region 22-25 and 123-125, the remaining portions of the molecule being unchanged in the four globins. Furthermore, all the amino acid replacements correspond to single point DNA mutations and (with the exception of the substitution Asp 22--&amp;gt;Asn in the beta 2-globin) involve uncharged substitutions.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17401914"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17401914"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17401914; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17401914]").text(description); $(".js-view-count[data-work-id=17401914]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17401914; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17401914']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17401914, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17401914]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17401914,"title":"Mass spectrometric analysis of rat hemoglobin by FAB-overlapping","translated_title":"","metadata":{"abstract":"1. The globin chain components of Sprague-Dawley rat hemoglobin were obtained by reverse-phase HPLC which showed the presence of two alpha-chain and four beta-chains. 2. The accurate molecular weight of each globin chain was determined by means of electrospray mass spectrometry. Extensive mass spectrometric analysis on several enzymatic digests by fast atom bombardment mass spectrometry (FAB-overlapping) meant to determine the complete sequence of the alpha-major and of the four beta-globins. 3. The primary structure of the alpha-major globin was found in agreement with literature data (Garrick et al., 1975 Biochem. J. 149, 245-258; Chua et al., 1987). 4. Sequence analysis of the four beta-globin chains showed that amino acid differences are restricted to two protein portions: the region 22-25 and 123-125, the remaining portions of the molecule being unchanged in the four globins. Furthermore, all the amino acid replacements correspond to single point DNA mutations and (with the exception of the substitution Asp 22--\u0026amp;gt;Asn in the beta 2-globin) involve uncharged substitutions.","publication_date":{"day":null,"month":null,"year":1988,"errors":{}},"publication_name":"International Journal of Biochemistry"},"translated_abstract":"1. The globin chain components of Sprague-Dawley rat hemoglobin were obtained by reverse-phase HPLC which showed the presence of two alpha-chain and four beta-chains. 2. The accurate molecular weight of each globin chain was determined by means of electrospray mass spectrometry. Extensive mass spectrometric analysis on several enzymatic digests by fast atom bombardment mass spectrometry (FAB-overlapping) meant to determine the complete sequence of the alpha-major and of the four beta-globins. 3. The primary structure of the alpha-major globin was found in agreement with literature data (Garrick et al., 1975 Biochem. J. 149, 245-258; Chua et al., 1987). 4. Sequence analysis of the four beta-globin chains showed that amino acid differences are restricted to two protein portions: the region 22-25 and 123-125, the remaining portions of the molecule being unchanged in the four globins. Furthermore, all the amino acid replacements correspond to single point DNA mutations and (with the exception of the substitution Asp 22--\u0026amp;gt;Asn in the beta 2-globin) involve uncharged substitutions.","internal_url":"https://www.academia.edu/17401914/Mass_spectrometric_analysis_of_rat_hemoglobin_by_FAB_overlapping","translated_internal_url":"","created_at":"2015-10-28T02:14:14.987-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Mass_spectrometric_analysis_of_rat_hemoglobin_by_FAB_overlapping","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry"},{"id":5769,"name":"Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Mass_Spectrometry"},{"id":246560,"name":"High Pressure Liquid Chromatography","url":"https://www.academia.edu/Documents/in/High_Pressure_Liquid_Chromatography"},{"id":375054,"name":"Rats","url":"https://www.academia.edu/Documents/in/Rats"},{"id":809881,"name":"Amino Acid Sequence","url":"https://www.academia.edu/Documents/in/Amino_Acid_Sequence"},{"id":1311261,"name":"Hemoglobins","url":"https://www.academia.edu/Documents/in/Hemoglobins"},{"id":1681026,"name":"Biochemistry and cell biology","url":"https://www.academia.edu/Documents/in/Biochemistry_and_cell_biology"},{"id":1900203,"name":"Hemolysis","url":"https://www.academia.edu/Documents/in/Hemolysis"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17401913"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17401913/Structural_analysis_of_styrene_oxide_haemoglobin_adducts_by_mass_spectrometry_identification_of_suitable_biomarkers_for_human_exposure_evaluation"><img alt="Research paper thumbnail of Structural analysis of styrene oxide/haemoglobin adducts by mass spectrometry: identification of suitable biomarkers for human exposure evaluation" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17401913/Structural_analysis_of_styrene_oxide_haemoglobin_adducts_by_mass_spectrometry_identification_of_suitable_biomarkers_for_human_exposure_evaluation">Structural analysis of styrene oxide/haemoglobin adducts by mass spectrometry: identification of suitable biomarkers for human exposure evaluation</a></div><div class="wp-workCard_item"><span>Rapid Communications in Mass Spectrometry</span><span>, 2002</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The structural characterisation of adducts formed by the in vitro reaction of haemoglobin (Hb) wi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The structural characterisation of adducts formed by the in vitro reaction of haemoglobin (Hb) with styrene oxide (SO), the most reactive metabolite of the industrial reagent styrene, was obtained by liquid chromatography/electrospray ionisation mass spectrometry (LC/ES-MS) analysis of modified tryptic peptides of human Hb chains. The reactive sites of human Hb towards SO were identified through characterisation of alkylated tryptic peptides by matrix-assisted laser desorption/ionisation with tandem mass spectrometry (MALDI-MS/MS). A procedure was set up based on this characterisation, allowing Hb modification to be assessed by monitoring SO/Hb adducts using HPLC with selected ion recording (SIR) mass spectrometry. By this methodology it was also possible to compare advantages and disadvantages of presently available strategies for the measurement of Hb adducts with SO. The results obtained could most plausibly lead to the optimisation of molecular dosimetry of SO adducts, and the analytical procedure described herein could be applied to the biological monitoring of styrene exposure in the workplace.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17401913"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17401913"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17401913; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17401913]").text(description); $(".js-view-count[data-work-id=17401913]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17401913; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17401913']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17401913, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17401913]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17401913,"title":"Structural analysis of styrene oxide/haemoglobin adducts by mass spectrometry: identification of suitable biomarkers for human exposure evaluation","translated_title":"","metadata":{"abstract":"The structural characterisation of adducts formed by the in vitro reaction of haemoglobin (Hb) with styrene oxide (SO), the most reactive metabolite of the industrial reagent styrene, was obtained by liquid chromatography/electrospray ionisation mass spectrometry (LC/ES-MS) analysis of modified tryptic peptides of human Hb chains. The reactive sites of human Hb towards SO were identified through characterisation of alkylated tryptic peptides by matrix-assisted laser desorption/ionisation with tandem mass spectrometry (MALDI-MS/MS). A procedure was set up based on this characterisation, allowing Hb modification to be assessed by monitoring SO/Hb adducts using HPLC with selected ion recording (SIR) mass spectrometry. By this methodology it was also possible to compare advantages and disadvantages of presently available strategies for the measurement of Hb adducts with SO. The results obtained could most plausibly lead to the optimisation of molecular dosimetry of SO adducts, and the analytical procedure described herein could be applied to the biological monitoring of styrene exposure in the workplace.","publication_date":{"day":null,"month":null,"year":2002,"errors":{}},"publication_name":"Rapid Communications in Mass Spectrometry"},"translated_abstract":"The structural characterisation of adducts formed by the in vitro reaction of haemoglobin (Hb) with styrene oxide (SO), the most reactive metabolite of the industrial reagent styrene, was obtained by liquid chromatography/electrospray ionisation mass spectrometry (LC/ES-MS) analysis of modified tryptic peptides of human Hb chains. The reactive sites of human Hb towards SO were identified through characterisation of alkylated tryptic peptides by matrix-assisted laser desorption/ionisation with tandem mass spectrometry (MALDI-MS/MS). A procedure was set up based on this characterisation, allowing Hb modification to be assessed by monitoring SO/Hb adducts using HPLC with selected ion recording (SIR) mass spectrometry. By this methodology it was also possible to compare advantages and disadvantages of presently available strategies for the measurement of Hb adducts with SO. The results obtained could most plausibly lead to the optimisation of molecular dosimetry of SO adducts, and the analytical procedure described herein could be applied to the biological monitoring of styrene exposure in the workplace.","internal_url":"https://www.academia.edu/17401913/Structural_analysis_of_styrene_oxide_haemoglobin_adducts_by_mass_spectrometry_identification_of_suitable_biomarkers_for_human_exposure_evaluation","translated_internal_url":"","created_at":"2015-10-28T02:14:14.895-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Structural_analysis_of_styrene_oxide_haemoglobin_adducts_by_mass_spectrometry_identification_of_suitable_biomarkers_for_human_exposure_evaluation","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":400,"name":"Earth Sciences","url":"https://www.academia.edu/Documents/in/Earth_Sciences"},{"id":5769,"name":"Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Mass_Spectrometry"},{"id":11801,"name":"Environmental Monitoring","url":"https://www.academia.edu/Documents/in/Environmental_Monitoring"},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences"},{"id":151086,"name":"Peptides","url":"https://www.academia.edu/Documents/in/Peptides"},{"id":184909,"name":"Structure Analysis","url":"https://www.academia.edu/Documents/in/Structure_Analysis"},{"id":184989,"name":"Carcinogens","url":"https://www.academia.edu/Documents/in/Carcinogens"},{"id":260118,"name":"CHEMICAL SCIENCES","url":"https://www.academia.edu/Documents/in/CHEMICAL_SCIENCES"},{"id":568482,"name":"Biological markers","url":"https://www.academia.edu/Documents/in/Biological_markers"},{"id":809881,"name":"Amino Acid Sequence","url":"https://www.academia.edu/Documents/in/Amino_Acid_Sequence"},{"id":1311261,"name":"Hemoglobins","url":"https://www.academia.edu/Documents/in/Hemoglobins"},{"id":1312021,"name":"Environmental Exposure","url":"https://www.academia.edu/Documents/in/Environmental_Exposure"},{"id":1485193,"name":"Rapid","url":"https://www.academia.edu/Documents/in/Rapid"},{"id":1724844,"name":"Molecular Structure","url":"https://www.academia.edu/Documents/in/Molecular_Structure"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17401912"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17401912/Rare_Association_of_Hyperglycinuria_and_Lenticonus_in_Two_Members_of_the_Same_Family"><img alt="Research paper thumbnail of Rare Association of Hyperglycinuria and Lenticonus in Two Members of the Same Family" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17401912/Rare_Association_of_Hyperglycinuria_and_Lenticonus_in_Two_Members_of_the_Same_Family">Rare Association of Hyperglycinuria and Lenticonus in Two Members of the Same Family</a></div><div class="wp-workCard_item"><span>Ophthalmologica</span><span>, 1979</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">2 cases of posterior lenticonus associated with hyperglycinuria without iminoaciduria, found in t...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">2 cases of posterior lenticonus associated with hyperglycinuria without iminoaciduria, found in the same family, were examined. After a review of the literature, the rarity of this association is stressed.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17401912"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17401912"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17401912; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17401912]").text(description); $(".js-view-count[data-work-id=17401912]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17401912; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17401912']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17401912, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17401912]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17401912,"title":"Rare Association of Hyperglycinuria and Lenticonus in Two Members of the Same Family","translated_title":"","metadata":{"abstract":"2 cases of posterior lenticonus associated with hyperglycinuria without iminoaciduria, found in the same family, were examined. After a review of the literature, the rarity of this association is stressed.","publication_date":{"day":null,"month":null,"year":1979,"errors":{}},"publication_name":"Ophthalmologica"},"translated_abstract":"2 cases of posterior lenticonus associated with hyperglycinuria without iminoaciduria, found in the same family, were examined. After a review of the literature, the rarity of this association is stressed.","internal_url":"https://www.academia.edu/17401912/Rare_Association_of_Hyperglycinuria_and_Lenticonus_in_Two_Members_of_the_Same_Family","translated_internal_url":"","created_at":"2015-10-28T02:14:14.795-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Rare_Association_of_Hyperglycinuria_and_Lenticonus_in_Two_Members_of_the_Same_Family","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":359001,"name":"Optometry and Ophthalmology","url":"https://www.academia.edu/Documents/in/Optometry_and_Ophthalmology"},{"id":712543,"name":"Glycine","url":"https://www.academia.edu/Documents/in/Glycine"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17401911"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/17401911/Determination_of_bromide_in_water_by_gas_chromatography"><img alt="Research paper thumbnail of Determination of bromide in water by gas chromatography" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/17401911/Determination_of_bromide_in_water_by_gas_chromatography">Determination of bromide in water by gas chromatography</a></div><div class="wp-workCard_item"><span>Journal of Chromatography A</span><span>, 1979</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17401911"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17401911"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17401911; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17401911]").text(description); $(".js-view-count[data-work-id=17401911]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17401911; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17401911']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17401911, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17401911]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17401911,"title":"Determination of bromide in water by gas chromatography","translated_title":"","metadata":{"publication_date":{"day":null,"month":null,"year":1979,"errors":{}},"publication_name":"Journal of Chromatography A"},"translated_abstract":null,"internal_url":"https://www.academia.edu/17401911/Determination_of_bromide_in_water_by_gas_chromatography","translated_internal_url":"","created_at":"2015-10-28T02:14:14.701-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Determination_of_bromide_in_water_by_gas_chromatography","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":48,"name":"Engineering","url":"https://www.academia.edu/Documents/in/Engineering"},{"id":923,"name":"Technology","url":"https://www.academia.edu/Documents/in/Technology"},{"id":260118,"name":"CHEMICAL SCIENCES","url":"https://www.academia.edu/Documents/in/CHEMICAL_SCIENCES"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17309284"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17309284/Mass_spectrometric_analysis_of_rat_hemoglobin_by_FAB_overlapping_Primary_structure_of_the_alpha_major_and_of_four_beta_constitutive_chains"><img alt="Research paper thumbnail of Mass spectrometric analysis of rat hemoglobin by FAB-overlapping. Primary structure of the alpha-major and of four beta constitutive chains" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17309284/Mass_spectrometric_analysis_of_rat_hemoglobin_by_FAB_overlapping_Primary_structure_of_the_alpha_major_and_of_four_beta_constitutive_chains">Mass spectrometric analysis of rat hemoglobin by FAB-overlapping. Primary structure of the alpha-major and of four beta constitutive chains</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://unina2.academia.edu/NicolaSannolo">Nicola Sannolo</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://unina.academia.edu/AntonioMalorni">Antonio Malorni</a></span></div><div class="wp-workCard_item"><span>International Journal of Biochemistry</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">1. The globin chain components of Sprague-Dawley rat hemoglobin were obtained by reverse-phase HP...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">1. The globin chain components of Sprague-Dawley rat hemoglobin were obtained by reverse-phase HPLC which showed the presence of two alpha-chain and four beta-chains. 2. The accurate molecular weight of each globin chain was determined by means of electrospray mass spectrometry. Extensive mass spectrometric analysis on several enzymatic digests by fast atom bombardment mass spectrometry (FAB-overlapping) meant to determine the complete sequence of the alpha-major and of the four beta-globins. 3. The primary structure of the alpha-major globin was found in agreement with literature data (Garrick et al., 1975 Biochem. J. 149, 245-258; Chua et al., 1987). 4. Sequence analysis of the four beta-globin chains showed that amino acid differences are restricted to two protein portions: the region 22-25 and 123-125, the remaining portions of the molecule being unchanged in the four globins. Furthermore, all the amino acid replacements correspond to single point DNA mutations and (with the exception of the substitution Asp 22--&amp;gt;Asn in the beta 2-globin) involve uncharged substitutions.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17309284"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17309284"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17309284; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17309284]").text(description); $(".js-view-count[data-work-id=17309284]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17309284; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17309284']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17309284, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17309284]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17309284,"title":"Mass spectrometric analysis of rat hemoglobin by FAB-overlapping. Primary structure of the alpha-major and of four beta constitutive chains","translated_title":"","metadata":{"abstract":"1. The globin chain components of Sprague-Dawley rat hemoglobin were obtained by reverse-phase HPLC which showed the presence of two alpha-chain and four beta-chains. 2. The accurate molecular weight of each globin chain was determined by means of electrospray mass spectrometry. Extensive mass spectrometric analysis on several enzymatic digests by fast atom bombardment mass spectrometry (FAB-overlapping) meant to determine the complete sequence of the alpha-major and of the four beta-globins. 3. The primary structure of the alpha-major globin was found in agreement with literature data (Garrick et al., 1975 Biochem. J. 149, 245-258; Chua et al., 1987). 4. Sequence analysis of the four beta-globin chains showed that amino acid differences are restricted to two protein portions: the region 22-25 and 123-125, the remaining portions of the molecule being unchanged in the four globins. Furthermore, all the amino acid replacements correspond to single point DNA mutations and (with the exception of the substitution Asp 22--\u0026amp;gt;Asn in the beta 2-globin) involve uncharged substitutions.","publication_name":"International Journal of Biochemistry"},"translated_abstract":"1. The globin chain components of Sprague-Dawley rat hemoglobin were obtained by reverse-phase HPLC which showed the presence of two alpha-chain and four beta-chains. 2. The accurate molecular weight of each globin chain was determined by means of electrospray mass spectrometry. Extensive mass spectrometric analysis on several enzymatic digests by fast atom bombardment mass spectrometry (FAB-overlapping) meant to determine the complete sequence of the alpha-major and of the four beta-globins. 3. The primary structure of the alpha-major globin was found in agreement with literature data (Garrick et al., 1975 Biochem. J. 149, 245-258; Chua et al., 1987). 4. Sequence analysis of the four beta-globin chains showed that amino acid differences are restricted to two protein portions: the region 22-25 and 123-125, the remaining portions of the molecule being unchanged in the four globins. Furthermore, all the amino acid replacements correspond to single point DNA mutations and (with the exception of the substitution Asp 22--\u0026amp;gt;Asn in the beta 2-globin) involve uncharged substitutions.","internal_url":"https://www.academia.edu/17309284/Mass_spectrometric_analysis_of_rat_hemoglobin_by_FAB_overlapping_Primary_structure_of_the_alpha_major_and_of_four_beta_constitutive_chains","translated_internal_url":"","created_at":"2015-10-26T08:49:25.773-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":8002756,"work_id":17309284,"tagging_user_id":36993140,"tagged_user_id":289263208,"co_author_invite_id":1318798,"email":"f***i@unina.it","display_order":0,"name":"Pasquale Ferranti","title":"Mass spectrometric analysis of rat hemoglobin by FAB-overlapping. Primary structure of the alpha-major and of four beta constitutive chains"},{"id":8002780,"work_id":17309284,"tagging_user_id":36993140,"tagged_user_id":455266,"co_author_invite_id":null,"email":"a***i@cnr.it","affiliation":"Università degli Studi di Napoli \"Federico II\"","display_order":4194304,"name":"Antonio Malorni","title":"Mass spectrometric analysis of rat hemoglobin by FAB-overlapping. Primary structure of the alpha-major and of four beta constitutive chains"}],"downloadable_attachments":[],"slug":"Mass_spectrometric_analysis_of_rat_hemoglobin_by_FAB_overlapping_Primary_structure_of_the_alpha_major_and_of_four_beta_constitutive_chains","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry"},{"id":5769,"name":"Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Mass_Spectrometry"},{"id":246560,"name":"High Pressure Liquid Chromatography","url":"https://www.academia.edu/Documents/in/High_Pressure_Liquid_Chromatography"},{"id":375054,"name":"Rats","url":"https://www.academia.edu/Documents/in/Rats"},{"id":809881,"name":"Amino Acid Sequence","url":"https://www.academia.edu/Documents/in/Amino_Acid_Sequence"},{"id":1311261,"name":"Hemoglobins","url":"https://www.academia.edu/Documents/in/Hemoglobins"},{"id":1681026,"name":"Biochemistry and cell biology","url":"https://www.academia.edu/Documents/in/Biochemistry_and_cell_biology"},{"id":1900203,"name":"Hemolysis","url":"https://www.academia.edu/Documents/in/Hemolysis"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17309283"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17309283/_Perception_of_alcoholism_risk_in_health_workers_medical_role_in_prevention_and_surveillance_"><img alt="Research paper thumbnail of [Perception of alcoholism risk in health workers: medical role in prevention and surveillance]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17309283/_Perception_of_alcoholism_risk_in_health_workers_medical_role_in_prevention_and_surveillance_">[Perception of alcoholism risk in health workers: medical role in prevention and surveillance]</a></div><div class="wp-workCard_item"><span>Giornale italiano di medicina del lavoro ed ergonomia</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">According to Italian laws (legge 125/01, art. 15, comma 1) about safety on workplaces, it&amp;#39...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">According to Italian laws (legge 125/01, art. 15, comma 1) about safety on workplaces, it&amp;#39;s forbidden alcohol drinking and taking for health workers (art. 8, comma 6, legge 5/06/2003 number 131) (e.g. anaesthesiology, surgery, radiology, nursing etc.). National alcoholism risk prevention program to assess number for year of accidents in health workplaces, is actually in progress leaded by Health Minister and Regional administration (e.g. Tuscany). Particularly, prevention program acts consist in comprehensive informations for health workers and their co- workers, about prevention and identification of alcoholism- related risks. To assess the size of alcohol problems in health workplaces, Occupational Health Medicine Institute of Second University of Naples is going to enrol 500 subjects (200 nursing students, 200 Specialist Registrars of different areas, 100 Consultants). Actually our population consists in 160 Specialist Registrars of different medical subjects (surgery, clinical and laboratory). To verify the importance of alcoholism risk perception, a not validated questionnaire was administrated. This original assessing instrument consists in 23 items with closed answers about demographic information, university, career, lifestyle, knowledge about rules taking alcoholic drinks. Results show a dangerous lack of information about alcohol health effects, even in Medical Specialist Registrars.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17309283"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17309283"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17309283; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17309283]").text(description); $(".js-view-count[data-work-id=17309283]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17309283; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17309283']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17309283, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17309283]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17309283,"title":"[Perception of alcoholism risk in health workers: medical role in prevention and surveillance]","translated_title":"","metadata":{"abstract":"According to Italian laws (legge 125/01, art. 15, comma 1) about safety on workplaces, it\u0026amp;#39;s forbidden alcohol drinking and taking for health workers (art. 8, comma 6, legge 5/06/2003 number 131) (e.g. anaesthesiology, surgery, radiology, nursing etc.). National alcoholism risk prevention program to assess number for year of accidents in health workplaces, is actually in progress leaded by Health Minister and Regional administration (e.g. Tuscany). Particularly, prevention program acts consist in comprehensive informations for health workers and their co- workers, about prevention and identification of alcoholism- related risks. To assess the size of alcohol problems in health workplaces, Occupational Health Medicine Institute of Second University of Naples is going to enrol 500 subjects (200 nursing students, 200 Specialist Registrars of different areas, 100 Consultants). Actually our population consists in 160 Specialist Registrars of different medical subjects (surgery, clinical and laboratory). To verify the importance of alcoholism risk perception, a not validated questionnaire was administrated. This original assessing instrument consists in 23 items with closed answers about demographic information, university, career, lifestyle, knowledge about rules taking alcoholic drinks. Results show a dangerous lack of information about alcohol health effects, even in Medical Specialist Registrars.","publication_name":"Giornale italiano di medicina del lavoro ed ergonomia"},"translated_abstract":"According to Italian laws (legge 125/01, art. 15, comma 1) about safety on workplaces, it\u0026amp;#39;s forbidden alcohol drinking and taking for health workers (art. 8, comma 6, legge 5/06/2003 number 131) (e.g. anaesthesiology, surgery, radiology, nursing etc.). National alcoholism risk prevention program to assess number for year of accidents in health workplaces, is actually in progress leaded by Health Minister and Regional administration (e.g. Tuscany). Particularly, prevention program acts consist in comprehensive informations for health workers and their co- workers, about prevention and identification of alcoholism- related risks. To assess the size of alcohol problems in health workplaces, Occupational Health Medicine Institute of Second University of Naples is going to enrol 500 subjects (200 nursing students, 200 Specialist Registrars of different areas, 100 Consultants). Actually our population consists in 160 Specialist Registrars of different medical subjects (surgery, clinical and laboratory). To verify the importance of alcoholism risk perception, a not validated questionnaire was administrated. This original assessing instrument consists in 23 items with closed answers about demographic information, university, career, lifestyle, knowledge about rules taking alcoholic drinks. Results show a dangerous lack of information about alcohol health effects, even in Medical Specialist Registrars.","internal_url":"https://www.academia.edu/17309283/_Perception_of_alcoholism_risk_in_health_workers_medical_role_in_prevention_and_surveillance_","translated_internal_url":"","created_at":"2015-10-26T08:49:25.467-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":8002744,"work_id":17309283,"tagging_user_id":36993140,"tagged_user_id":null,"co_author_invite_id":1787099,"email":"f***i@unina2.it","display_order":0,"name":"Francesco Liotti","title":"[Perception of alcoholism risk in health workers: medical role in prevention and surveillance]"},{"id":8002947,"work_id":17309283,"tagging_user_id":36993140,"tagged_user_id":null,"co_author_invite_id":195909,"email":"c***o@ausl.bologna.it","display_order":4194304,"name":"C. Di Stefano","title":"[Perception of alcoholism risk in health workers: medical role in prevention and surveillance]"},{"id":8002948,"work_id":17309283,"tagging_user_id":36993140,"tagged_user_id":null,"co_author_invite_id":1787149,"email":"m***a@libero.it","display_order":6291456,"name":"M. Peduto","title":"[Perception of alcoholism risk in health workers: medical role in prevention and surveillance]"},{"id":8002949,"work_id":17309283,"tagging_user_id":36993140,"tagged_user_id":null,"co_author_invite_id":1787150,"email":"g***o@unipv.it","display_order":7340032,"name":"M. Ruberto","title":"[Perception of alcoholism risk in health workers: medical role in prevention and surveillance]"},{"id":8002950,"work_id":17309283,"tagging_user_id":36993140,"tagged_user_id":null,"co_author_invite_id":1787151,"email":"a***l@unina2.it","display_order":7864320,"name":"A. Di Tella","title":"[Perception of alcoholism risk in health workers: medical role in prevention and surveillance]"}],"downloadable_attachments":[],"slug":"_Perception_of_alcoholism_risk_in_health_workers_medical_role_in_prevention_and_surveillance_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":91863,"name":"Alcoholism","url":"https://www.academia.edu/Documents/in/Alcoholism"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors"},{"id":327850,"name":"Questionnaires","url":"https://www.academia.edu/Documents/in/Questionnaires"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1"},{"id":1824236,"name":"Health Personnel","url":"https://www.academia.edu/Documents/in/Health_Personnel"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17309282"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17309282/Ultrafine_particles_and_effects_on_the_organism_Literature_review"><img alt="Research paper thumbnail of Ultrafine particles and effects on the organism: Literature review" class="work-thumbnail" src="https://attachments.academia-assets.com/39437950/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17309282/Ultrafine_particles_and_effects_on_the_organism_Literature_review">Ultrafine particles and effects on the organism: Literature review</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/PaolaPedata">Paola Pedata</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://unina2.academia.edu/NicolaSannolo">Nicola Sannolo</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/ElpidioGarzillo">Elpidio Garzillo</a></span></div><div class="wp-workCard_item"><span>Giornale italiano di medicina del lavoro ed ergonomia</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="5a7c3807119fe8eca81dfc27c793cd93" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":39437950,"asset_id":17309282,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/39437950/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17309282"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17309282"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17309282; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17309282]").text(description); $(".js-view-count[data-work-id=17309282]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17309282; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17309282']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17309282, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "5a7c3807119fe8eca81dfc27c793cd93" } } $('.js-work-strip[data-work-id=17309282]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17309282,"title":"Ultrafine particles and effects on the organism: Literature review","translated_title":"","metadata":{"grobid_abstract":"Negli ultimi anni, l'interesse della comunità scientifica internazionale nel campo della ricerca si è incentrato sullo studio degli effetti del particolato ultrafine sulla salute umana. Le particelle ultrafini (PM 0.1 : diametro aerodinamico medio inferiore a 0.1 µm) sono complesse miscele di sostanze organiche ed inorganiche, dotate di intrinseca tossicità. Le loro piccole dimensioni le rendono degne di particolare attenzione in quanto sono in grado di penetrare fino alle vie aeree più profonde, sfuggendo ai normali meccanismi di difesa polmonare, ed entrare nel circolo sanguigno (1-6).","publication_name":"Giornale italiano di medicina del lavoro ed ergonomia","grobid_abstract_attachment_id":39437950},"translated_abstract":null,"internal_url":"https://www.academia.edu/17309282/Ultrafine_particles_and_effects_on_the_organism_Literature_review","translated_internal_url":"","created_at":"2015-10-26T08:49:25.044-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":8002859,"work_id":17309282,"tagging_user_id":36993140,"tagged_user_id":37126197,"co_author_invite_id":1787121,"email":"p***a@unina2.it","display_order":0,"name":"Paola Pedata","title":"Ultrafine particles and effects on the organism: Literature review"},{"id":8002864,"work_id":17309282,"tagging_user_id":36993140,"tagged_user_id":37146778,"co_author_invite_id":1787122,"email":"e***o@gmail.com","display_order":4194304,"name":"Elpidio Garzillo","title":"Ultrafine particles and effects on the organism: Literature review"}],"downloadable_attachments":[{"id":39437950,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39437950/thumbnails/1.jpg","file_name":"Ultrafine_particles_and_effects_on_the_o20151026-32577-dp5awl.pdf","download_url":"https://www.academia.edu/attachments/39437950/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Ultrafine_particles_and_effects_on_the_o.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39437950/Ultrafine_particles_and_effects_on_the_o20151026-32577-dp5awl-libre.pdf?1445895570=\u0026response-content-disposition=attachment%3B+filename%3DUltrafine_particles_and_effects_on_the_o.pdf\u0026Expires=1732833882\u0026Signature=HymdBiQbkywUM9CfGQ5y~81sOJM-ZunDBHWQNs10mmTZHIJ81TJMaVXfO~h4uwF2OWaNLkwoshw0HdBCDgscStZISFA~Sws6lzGTXNy6xqPuHwx99FIg28gbZc3qqcRNx6ks4yp4mVTtw7BoMcG9iF3BTg2S~UJAp2cm6100gfCA6L9eNjMMqSVMy7De2qQ5kV4D3CITjsuoyUprxiY6kO5q7z2DQGLBihuACie93TB2R82zd8zFVBETkAm3gxA9C8FR7vws7uVdiCri-rxkKlDl3JQnbV9LUJplh91um0rg4aQ~aauFo99MkDIxsdKxFE~1r9lVGGpKkDFWZu-pAA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Ultrafine_particles_and_effects_on_the_organism_Literature_review","translated_slug":"","page_count":9,"language":"it","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[{"id":39437950,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39437950/thumbnails/1.jpg","file_name":"Ultrafine_particles_and_effects_on_the_o20151026-32577-dp5awl.pdf","download_url":"https://www.academia.edu/attachments/39437950/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Ultrafine_particles_and_effects_on_the_o.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39437950/Ultrafine_particles_and_effects_on_the_o20151026-32577-dp5awl-libre.pdf?1445895570=\u0026response-content-disposition=attachment%3B+filename%3DUltrafine_particles_and_effects_on_the_o.pdf\u0026Expires=1732833882\u0026Signature=HymdBiQbkywUM9CfGQ5y~81sOJM-ZunDBHWQNs10mmTZHIJ81TJMaVXfO~h4uwF2OWaNLkwoshw0HdBCDgscStZISFA~Sws6lzGTXNy6xqPuHwx99FIg28gbZc3qqcRNx6ks4yp4mVTtw7BoMcG9iF3BTg2S~UJAp2cm6100gfCA6L9eNjMMqSVMy7De2qQ5kV4D3CITjsuoyUprxiY6kO5q7z2DQGLBihuACie93TB2R82zd8zFVBETkAm3gxA9C8FR7vws7uVdiCri-rxkKlDl3JQnbV9LUJplh91um0rg4aQ~aauFo99MkDIxsdKxFE~1r9lVGGpKkDFWZu-pAA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17309281"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17309281/Biologically_effective_dose_biomarkers"><img alt="Research paper thumbnail of Biologically effective dose biomarkers" class="work-thumbnail" src="https://attachments.academia-assets.com/39437949/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17309281/Biologically_effective_dose_biomarkers">Biologically effective dose biomarkers</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/NMiraglia">N. Miraglia</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://unina2.academia.edu/NicolaSannolo">Nicola Sannolo</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/SilviaFustinoni">Silvia Fustinoni</a></span></div><div class="wp-workCard_item"><span>Giornale italiano di medicina del lavoro ed ergonomia</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="af78fea79498b6fd7e1491797ae6abf3" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":39437949,"asset_id":17309281,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/39437949/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17309281"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17309281"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17309281; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17309281]").text(description); $(".js-view-count[data-work-id=17309281]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17309281; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17309281']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17309281, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "af78fea79498b6fd7e1491797ae6abf3" } } $('.js-work-strip[data-work-id=17309281]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17309281,"title":"Biologically effective dose biomarkers","translated_title":"","metadata":{"publication_name":"Giornale italiano di medicina del lavoro ed ergonomia"},"translated_abstract":null,"internal_url":"https://www.academia.edu/17309281/Biologically_effective_dose_biomarkers","translated_internal_url":"","created_at":"2015-10-26T08:49:24.694-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":8002738,"work_id":17309281,"tagging_user_id":36993140,"tagged_user_id":37198082,"co_author_invite_id":1787097,"email":"n***a@unina2.it","display_order":0,"name":"N. Miraglia","title":"Biologically effective dose biomarkers"},{"id":8002944,"work_id":17309281,"tagging_user_id":36993140,"tagged_user_id":null,"co_author_invite_id":302786,"email":"d***g@arpa.puglia.it","display_order":4194304,"name":"G. Assennato","title":"Biologically effective dose biomarkers"},{"id":8002945,"work_id":17309281,"tagging_user_id":36993140,"tagged_user_id":null,"co_author_invite_id":313834,"email":"c***o@ux1.unipd.it","display_order":6291456,"name":"E. Clonfero","title":"Biologically effective dose biomarkers"},{"id":8002946,"work_id":17309281,"tagging_user_id":36993140,"tagged_user_id":48675815,"co_author_invite_id":496494,"email":"s***i@unimi.it","display_order":7340032,"name":"Silvia Fustinoni","title":"Biologically effective dose biomarkers"}],"downloadable_attachments":[{"id":39437949,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39437949/thumbnails/1.jpg","file_name":"Biologically_effective_dose_biomarkers20151026-32584-bfd6no.pdf","download_url":"https://www.academia.edu/attachments/39437949/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Biologically_effective_dose_biomarkers.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39437949/Biologically_effective_dose_biomarkers20151026-32584-bfd6no-libre.pdf?1445895570=\u0026response-content-disposition=attachment%3B+filename%3DBiologically_effective_dose_biomarkers.pdf\u0026Expires=1732833882\u0026Signature=JIRDizHJmGoiUnoMrRU7bYEjaTdmiDG7cinSdiM7vcrEyXlUHiNZJQoxxk3CaiiA8U63G0-ACwLVYEvcjzD0EfW4MEjVFBsc1vNrO1Ht3u~u82zJpPM~XWkaFdplrKN6tt~agaFVxjXhB7QgJeWFatp5tPacvf909fZNlMCUbosTmkLFVptU9DFcxQ1zkaZUrI3jA6Opc4Ew8DA9t5FmkyM1O0XtiEJgRSWV632T1HD9TZs5DicXQnvoERDWnszaBXt-kCIUB5xkRi4B4DOArhD0-~Qv8lVWeT6vm-~VikF0nJI~akSeM5uL72bU7L6MDHUMpjzSsNUuKdo3E9GAlg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Biologically_effective_dose_biomarkers","translated_slug":"","page_count":4,"language":"it","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[{"id":39437949,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39437949/thumbnails/1.jpg","file_name":"Biologically_effective_dose_biomarkers20151026-32584-bfd6no.pdf","download_url":"https://www.academia.edu/attachments/39437949/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Biologically_effective_dose_biomarkers.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39437949/Biologically_effective_dose_biomarkers20151026-32584-bfd6no-libre.pdf?1445895570=\u0026response-content-disposition=attachment%3B+filename%3DBiologically_effective_dose_biomarkers.pdf\u0026Expires=1732833882\u0026Signature=JIRDizHJmGoiUnoMrRU7bYEjaTdmiDG7cinSdiM7vcrEyXlUHiNZJQoxxk3CaiiA8U63G0-ACwLVYEvcjzD0EfW4MEjVFBsc1vNrO1Ht3u~u82zJpPM~XWkaFdplrKN6tt~agaFVxjXhB7QgJeWFatp5tPacvf909fZNlMCUbosTmkLFVptU9DFcxQ1zkaZUrI3jA6Opc4Ew8DA9t5FmkyM1O0XtiEJgRSWV632T1HD9TZs5DicXQnvoERDWnszaBXt-kCIUB5xkRi4B4DOArhD0-~Qv8lVWeT6vm-~VikF0nJI~akSeM5uL72bU7L6MDHUMpjzSsNUuKdo3E9GAlg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":9478,"name":"Diet","url":"https://www.academia.edu/Documents/in/Diet"},{"id":11801,"name":"Environmental Monitoring","url":"https://www.academia.edu/Documents/in/Environmental_Monitoring"},{"id":19870,"name":"Research","url":"https://www.academia.edu/Documents/in/Research"},{"id":75318,"name":"Smoking","url":"https://www.academia.edu/Documents/in/Smoking"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors"},{"id":396914,"name":"Occupational Exposure","url":"https://www.academia.edu/Documents/in/Occupational_Exposure"},{"id":432116,"name":"Xenobiotics","url":"https://www.academia.edu/Documents/in/Xenobiotics"},{"id":568482,"name":"Biological markers","url":"https://www.academia.edu/Documents/in/Biological_markers"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1"},{"id":962276,"name":"Occupational Diseases","url":"https://www.academia.edu/Documents/in/Occupational_Diseases"},{"id":1162913,"name":"Mutagens","url":"https://www.academia.edu/Documents/in/Mutagens"},{"id":1232430,"name":"Genetic Markers","url":"https://www.academia.edu/Documents/in/Genetic_Markers"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17309280"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17309280/Managment_of_tuberculosis_in_an_University_of_Campania"><img alt="Research paper thumbnail of Managment of tuberculosis in an University of Campania" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17309280/Managment_of_tuberculosis_in_an_University_of_Campania">Managment of tuberculosis in an University of Campania</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/ElpidioGarzillo">Elpidio Garzillo</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://unina2.academia.edu/NicolaSannolo">Nicola Sannolo</a></span></div><div class="wp-workCard_item"><span>Giornale italiano di medicina del lavoro ed ergonomia</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Tuberculosis (TBC) is an infectious disease with the highest mortality and morbidity by single pa...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Tuberculosis (TBC) is an infectious disease with the highest mortality and morbidity by single pathogen, affecting about one third of worldwide population. Although Mantoux test is the most used, IGRA (Interferon-gamma Release Assays) tests seem to give good results for presumptive diagnosis of active or latent tuberculosis. From June 2011 to June 2012 we made about 1,000 visits for TBC prevention among the exposed to biological risks of our University. The management of suspected latent or active tuberculosis infection was carried out in collaboration with the pulmonologist, assessing the risk of contagion among exposed or affected operators. Health surveillance protocol and judgements of suitability for specific task were made not only in consideration of worker health, but also considerating the possible risk for patients, since this disease is a major problem for public health.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17309280"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17309280"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17309280; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17309280]").text(description); $(".js-view-count[data-work-id=17309280]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17309280; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17309280']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17309280, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17309280]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17309280,"title":"Managment of tuberculosis in an University of Campania","translated_title":"","metadata":{"abstract":"Tuberculosis (TBC) is an infectious disease with the highest mortality and morbidity by single pathogen, affecting about one third of worldwide population. Although Mantoux test is the most used, IGRA (Interferon-gamma Release Assays) tests seem to give good results for presumptive diagnosis of active or latent tuberculosis. From June 2011 to June 2012 we made about 1,000 visits for TBC prevention among the exposed to biological risks of our University. The management of suspected latent or active tuberculosis infection was carried out in collaboration with the pulmonologist, assessing the risk of contagion among exposed or affected operators. Health surveillance protocol and judgements of suitability for specific task were made not only in consideration of worker health, but also considerating the possible risk for patients, since this disease is a major problem for public health.","publication_name":"Giornale italiano di medicina del lavoro ed ergonomia"},"translated_abstract":"Tuberculosis (TBC) is an infectious disease with the highest mortality and morbidity by single pathogen, affecting about one third of worldwide population. Although Mantoux test is the most used, IGRA (Interferon-gamma Release Assays) tests seem to give good results for presumptive diagnosis of active or latent tuberculosis. From June 2011 to June 2012 we made about 1,000 visits for TBC prevention among the exposed to biological risks of our University. The management of suspected latent or active tuberculosis infection was carried out in collaboration with the pulmonologist, assessing the risk of contagion among exposed or affected operators. Health surveillance protocol and judgements of suitability for specific task were made not only in consideration of worker health, but also considerating the possible risk for patients, since this disease is a major problem for public health.","internal_url":"https://www.academia.edu/17309280/Managment_of_tuberculosis_in_an_University_of_Campania","translated_internal_url":"","created_at":"2015-10-26T08:49:24.271-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":8002863,"work_id":17309280,"tagging_user_id":36993140,"tagged_user_id":37146778,"co_author_invite_id":1787122,"email":"e***o@gmail.com","display_order":0,"name":"Elpidio Garzillo","title":"Managment of tuberculosis in an University of Campania"},{"id":8002905,"work_id":17309280,"tagging_user_id":36993140,"tagged_user_id":16904222,"co_author_invite_id":null,"email":"m***n@alice.it","display_order":4194304,"name":"Maria Monaco","title":"Managment of tuberculosis in an University of Campania"}],"downloadable_attachments":[],"slug":"Managment_of_tuberculosis_in_an_University_of_Campania","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":45213,"name":"Italy","url":"https://www.academia.edu/Documents/in/Italy"},{"id":62235,"name":"Tuberculosis","url":"https://www.academia.edu/Documents/in/Tuberculosis"},{"id":159736,"name":"Universities","url":"https://www.academia.edu/Documents/in/Universities"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17309279"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17309279/Studio_dell_esposizione_a_solventi_nell_industria_della_gomma_e_della_plastica_attraverso_il_monitoraggio_ambientale_e_il_monitoraggio_biologico_Applicazione_delle_metodiche_messe_a_punto_e_validate_dal_Gruppo_di_Studio_INAIL_SUN_nel_triennio_2009_2012"><img alt="Research paper thumbnail of Studio dell’esposizione a solventi nell’industria della gomma e della plastica, attraverso il monitoraggio ambientale e il monitoraggio biologico. Applicazione delle metodiche messe a punto e validate dal Gruppo di Studio INAIL-SUN nel triennio 2009-2012" class="work-thumbnail" src="https://attachments.academia-assets.com/39437953/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17309279/Studio_dell_esposizione_a_solventi_nell_industria_della_gomma_e_della_plastica_attraverso_il_monitoraggio_ambientale_e_il_monitoraggio_biologico_Applicazione_delle_metodiche_messe_a_punto_e_validate_dal_Gruppo_di_Studio_INAIL_SUN_nel_triennio_2009_2012">Studio dell’esposizione a solventi nell’industria della gomma e della plastica, attraverso il monitoraggio ambientale e il monitoraggio biologico. Applicazione delle metodiche messe a punto e validate dal Gruppo di Studio INAIL-SUN nel triennio 2009-2012</a></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="3a7ff1aef0ae4be645543d8f2e3c9af7" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":39437953,"asset_id":17309279,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/39437953/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17309279"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17309279"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17309279; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17309279]").text(description); $(".js-view-count[data-work-id=17309279]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17309279; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17309279']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17309279, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "3a7ff1aef0ae4be645543d8f2e3c9af7" } } $('.js-work-strip[data-work-id=17309279]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17309279,"title":"Studio dell’esposizione a solventi nell’industria della gomma e della plastica, attraverso il monitoraggio ambientale e il monitoraggio biologico. Applicazione delle metodiche messe a punto e validate dal Gruppo di Studio INAIL-SUN nel triennio 2009-2012","translated_title":"","metadata":{},"translated_abstract":null,"internal_url":"https://www.academia.edu/17309279/Studio_dell_esposizione_a_solventi_nell_industria_della_gomma_e_della_plastica_attraverso_il_monitoraggio_ambientale_e_il_monitoraggio_biologico_Applicazione_delle_metodiche_messe_a_punto_e_validate_dal_Gruppo_di_Studio_INAIL_SUN_nel_triennio_2009_2012","translated_internal_url":"","created_at":"2015-10-26T08:49:23.594-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":8002886,"work_id":17309279,"tagging_user_id":36993140,"tagged_user_id":null,"co_author_invite_id":1787132,"email":"g***5@campus.unimib.it","display_order":0,"name":"Giuliana Genovese","title":"Studio dell’esposizione a solventi nell’industria della gomma e della plastica, attraverso il monitoraggio ambientale e il monitoraggio biologico. Applicazione delle metodiche messe a punto e validate dal Gruppo di Studio INAIL-SUN nel triennio 2009-2012"},{"id":8002928,"work_id":17309279,"tagging_user_id":36993140,"tagged_user_id":21283568,"co_author_invite_id":null,"email":"c***9@libero.it","display_order":4194304,"name":"Cinzia Novi","title":"Studio dell’esposizione a solventi nell’industria della gomma e della plastica, attraverso il monitoraggio ambientale e il monitoraggio biologico. Applicazione delle metodiche messe a punto e validate dal Gruppo di Studio INAIL-SUN nel triennio 2009-2012"},{"id":8002933,"work_id":17309279,"tagging_user_id":36993140,"tagged_user_id":12642481,"co_author_invite_id":null,"email":"r***5@gmail.com","display_order":6291456,"name":"Roberto D'angelo","title":"Studio dell’esposizione a solventi nell’industria della gomma e della plastica, attraverso il monitoraggio ambientale e il monitoraggio biologico. Applicazione delle metodiche messe a punto e validate dal Gruppo di Studio INAIL-SUN nel triennio 2009-2012"}],"downloadable_attachments":[{"id":39437953,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39437953/thumbnails/1.jpg","file_name":"Studio_dellesposizione_a_solventi_nellin20151026-32577-13q3k88.pdf","download_url":"https://www.academia.edu/attachments/39437953/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Studio_dell_esposizione_a_solventi_nell.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39437953/Studio_dellesposizione_a_solventi_nellin20151026-32577-13q3k88.pdf?1445891794=\u0026response-content-disposition=attachment%3B+filename%3DStudio_dell_esposizione_a_solventi_nell.pdf\u0026Expires=1732833882\u0026Signature=gdzJZQL9SWd8IuRVHSw-Ni2C36nUmufR~DJQZ~~fTo4EzbCTqGe0VdZb3C4~prwbL9DUNAPrnAsl8JdIvlV2pw1d6ZpOO0As5kuRa0buaD7pQq2AvfktKsZgl10JrKJ51lETzq-Ha3LPBz7jLm0fzCtdICtigFA8hkMZqxdkCnw9TMJXowJAOFsc-7WnG~-bZOlHR9ua6u23HarFqUDizuFJItYuhx8ZzGSJnwJQua483FgP3ZLRCL50iWMkQ~nTILeQfQC~hJgkmOLqxoWS9aJ33b15mmaRNQYS-Lk5S80IhwrW1Q5fJqO9j8Jd52pO1CuUXk8sDu5u5DTkCohYYg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Studio_dell_esposizione_a_solventi_nell_industria_della_gomma_e_della_plastica_attraverso_il_monitoraggio_ambientale_e_il_monitoraggio_biologico_Applicazione_delle_metodiche_messe_a_punto_e_validate_dal_Gruppo_di_Studio_INAIL_SUN_nel_triennio_2009_2012","translated_slug":"","page_count":5,"language":"it","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[{"id":39437953,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39437953/thumbnails/1.jpg","file_name":"Studio_dellesposizione_a_solventi_nellin20151026-32577-13q3k88.pdf","download_url":"https://www.academia.edu/attachments/39437953/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Studio_dell_esposizione_a_solventi_nell.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39437953/Studio_dellesposizione_a_solventi_nellin20151026-32577-13q3k88.pdf?1445891794=\u0026response-content-disposition=attachment%3B+filename%3DStudio_dell_esposizione_a_solventi_nell.pdf\u0026Expires=1732833882\u0026Signature=gdzJZQL9SWd8IuRVHSw-Ni2C36nUmufR~DJQZ~~fTo4EzbCTqGe0VdZb3C4~prwbL9DUNAPrnAsl8JdIvlV2pw1d6ZpOO0As5kuRa0buaD7pQq2AvfktKsZgl10JrKJ51lETzq-Ha3LPBz7jLm0fzCtdICtigFA8hkMZqxdkCnw9TMJXowJAOFsc-7WnG~-bZOlHR9ua6u23HarFqUDizuFJItYuhx8ZzGSJnwJQua483FgP3ZLRCL50iWMkQ~nTILeQfQC~hJgkmOLqxoWS9aJ33b15mmaRNQYS-Lk5S80IhwrW1Q5fJqO9j8Jd52pO1CuUXk8sDu5u5DTkCohYYg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17309278"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17309278/Usefulness_and_limits_of_a_new_method_for_biochemical_screening_of_lysosomal_storage_diseases"><img alt="Research paper thumbnail of Usefulness and limits of a new method for biochemical screening of lysosomal storage diseases" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17309278/Usefulness_and_limits_of_a_new_method_for_biochemical_screening_of_lysosomal_storage_diseases">Usefulness and limits of a new method for biochemical screening of lysosomal storage diseases</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://unina2.academia.edu/NicolaSannolo">Nicola Sannolo</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/FFalco2">F. Falco</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://unina.academia.edu/PietroStrisciuglio">Pietro Strisciuglio</a></span></div><div class="wp-workCard_item"><span>Acta neurologica</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17309278"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17309278"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17309278; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17309278]").text(description); $(".js-view-count[data-work-id=17309278]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17309278; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17309278']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17309278, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17309278]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17309278,"title":"Usefulness and limits of a new method for biochemical screening of lysosomal storage diseases","translated_title":"","metadata":{"publication_name":"Acta neurologica"},"translated_abstract":null,"internal_url":"https://www.academia.edu/17309278/Usefulness_and_limits_of_a_new_method_for_biochemical_screening_of_lysosomal_storage_diseases","translated_internal_url":"","created_at":"2015-10-26T08:49:23.097-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":8002940,"work_id":17309278,"tagging_user_id":36993140,"tagged_user_id":53202663,"co_author_invite_id":1787147,"email":"d***o@tin.it","display_order":0,"name":"F. Falco","title":"Usefulness and limits of a new method for biochemical screening of lysosomal storage diseases"},{"id":8002941,"work_id":17309278,"tagging_user_id":36993140,"tagged_user_id":33059454,"co_author_invite_id":null,"email":"p***o@unina.it","affiliation":"Università degli Studi di Napoli \"Federico II\"","display_order":4194304,"name":"Pietro Strisciuglio","title":"Usefulness and limits of a new method for biochemical screening of lysosomal storage diseases"},{"id":8002942,"work_id":17309278,"tagging_user_id":36993140,"tagged_user_id":null,"co_author_invite_id":1787148,"email":"r***n@mail.elmundo.com.bo","display_order":6291456,"name":"P. Mundo","title":"Usefulness and limits of a new method for biochemical screening of lysosomal storage diseases"},{"id":8002943,"work_id":17309278,"tagging_user_id":36993140,"tagged_user_id":22901615,"co_author_invite_id":null,"email":"g***o@gmail.com","display_order":7340032,"name":"gian maro di domenico","title":"Usefulness and limits of a new method for biochemical screening of lysosomal storage diseases"}],"downloadable_attachments":[],"slug":"Usefulness_and_limits_of_a_new_method_for_biochemical_screening_of_lysosomal_storage_diseases","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":23868,"name":"Intellectual Disability","url":"https://www.academia.edu/Documents/in/Intellectual_Disability"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":108568,"name":"Inborn errors of metabolism","url":"https://www.academia.edu/Documents/in/Inborn_errors_of_metabolism"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> </div><div class="profile--tab_content_container js-tab-pane tab-pane" data-section-id="3848058" id="papers"><div class="js-work-strip profile--work_container" data-work-id="21133190"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/21133190/Study_of_interaction_of_styrene_oxide_with_Angiotensin_by_mass_spectrometry"><img alt="Research paper thumbnail of Study of interaction of styrene oxide with Angiotensin by mass spectrometry" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/21133190/Study_of_interaction_of_styrene_oxide_with_Angiotensin_by_mass_spectrometry">Study of interaction of styrene oxide with Angiotensin by mass spectrometry</a></div><div class="wp-workCard_item"><span>Carcinogenesis</span><span>, 1992</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The present study describes how mass spectrometry was extensively applied to the characterization...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The present study describes how mass spectrometry was extensively applied to the characterization and quantification of modified amino acids within the polypeptide chain of Angiotensin I, chosen as model substrate, combining the use of fast atom bombardment mass spectrometry with gas chromatography--mass spectrometry. The reaction products after in vitro incubation of Angiotensin I with styrene oxide, a well known carcinogen, under different conditions, have been characterized: a prominent reactivity of several potential nucleophilic sites of Angiotensin I was shown, including two histidine residues and a tyrosine residue; it is worth noting that it has never been stated that tyrosine is highly reactive with styrene oxide. The results obtained demonstrate the usefulness of mass spectrometry for the structural determination of chemically modified amino acids in peptides and proteins, and the presence of a reliable relationship between reaction conditions and the production of alkylated amino acids. This characterization procedure offers the possibility of identifying reactive sites following exposure to unknown alkylating agents.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="21133190"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="21133190"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 21133190; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=21133190]").text(description); $(".js-view-count[data-work-id=21133190]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 21133190; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='21133190']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 21133190, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=21133190]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":21133190,"title":"Study of interaction of styrene oxide with Angiotensin by mass spectrometry","translated_title":"","metadata":{"abstract":"The present study describes how mass spectrometry was extensively applied to the characterization and quantification of modified amino acids within the polypeptide chain of Angiotensin I, chosen as model substrate, combining the use of fast atom bombardment mass spectrometry with gas chromatography--mass spectrometry. The reaction products after in vitro incubation of Angiotensin I with styrene oxide, a well known carcinogen, under different conditions, have been characterized: a prominent reactivity of several potential nucleophilic sites of Angiotensin I was shown, including two histidine residues and a tyrosine residue; it is worth noting that it has never been stated that tyrosine is highly reactive with styrene oxide. The results obtained demonstrate the usefulness of mass spectrometry for the structural determination of chemically modified amino acids in peptides and proteins, and the presence of a reliable relationship between reaction conditions and the production of alkylated amino acids. This characterization procedure offers the possibility of identifying reactive sites following exposure to unknown alkylating agents.","publication_date":{"day":null,"month":null,"year":1992,"errors":{}},"publication_name":"Carcinogenesis"},"translated_abstract":"The present study describes how mass spectrometry was extensively applied to the characterization and quantification of modified amino acids within the polypeptide chain of Angiotensin I, chosen as model substrate, combining the use of fast atom bombardment mass spectrometry with gas chromatography--mass spectrometry. The reaction products after in vitro incubation of Angiotensin I with styrene oxide, a well known carcinogen, under different conditions, have been characterized: a prominent reactivity of several potential nucleophilic sites of Angiotensin I was shown, including two histidine residues and a tyrosine residue; it is worth noting that it has never been stated that tyrosine is highly reactive with styrene oxide. The results obtained demonstrate the usefulness of mass spectrometry for the structural determination of chemically modified amino acids in peptides and proteins, and the presence of a reliable relationship between reaction conditions and the production of alkylated amino acids. This characterization procedure offers the possibility of identifying reactive sites following exposure to unknown alkylating agents.","internal_url":"https://www.academia.edu/21133190/Study_of_interaction_of_styrene_oxide_with_Angiotensin_by_mass_spectrometry","translated_internal_url":"","created_at":"2016-01-29T06:10:59.282-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Study_of_interaction_of_styrene_oxide_with_Angiotensin_by_mass_spectrometry","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":5769,"name":"Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Mass_Spectrometry"},{"id":166448,"name":"Gas Chromatography","url":"https://www.academia.edu/Documents/in/Gas_Chromatography"},{"id":246560,"name":"High Pressure Liquid Chromatography","url":"https://www.academia.edu/Documents/in/High_Pressure_Liquid_Chromatography"},{"id":340262,"name":"Carcinogenesis","url":"https://www.academia.edu/Documents/in/Carcinogenesis"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="1326593"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/1326593/A_novel_approach_for_identification_and_measurement_of_hemoglobin_adducts_with_1_2_3_4_diepoxybutane_by_liquid_chromatography_electrospray_ionisation_mass_"><img alt="Research paper thumbnail of A novel approach for identification and measurement of hemoglobin adducts with 1, 2, 3, 4‐diepoxybutane by liquid chromatography/electrospray ionisation mass …" class="work-thumbnail" src="https://attachments.academia-assets.com/51026864/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/1326593/A_novel_approach_for_identification_and_measurement_of_hemoglobin_adducts_with_1_2_3_4_diepoxybutane_by_liquid_chromatography_electrospray_ionisation_mass_">A novel approach for identification and measurement of hemoglobin adducts with 1, 2, 3, 4‐diepoxybutane by liquid chromatography/electrospray ionisation mass …</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://unina2.academia.edu/NicolaSannolo">Nicola Sannolo</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://unina.academia.edu/AntonioMalorni">Antonio Malorni</a></span></div><div class="wp-workCard_item"><span>Rapid …</span><span>, Jan 1, 2001</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="9b7da16d6728292d4e2fd40ebfcd7fe5" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":51026864,"asset_id":1326593,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/51026864/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="1326593"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="1326593"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 1326593; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=1326593]").text(description); $(".js-view-count[data-work-id=1326593]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 1326593; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='1326593']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 1326593, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "9b7da16d6728292d4e2fd40ebfcd7fe5" } } $('.js-work-strip[data-work-id=1326593]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":1326593,"title":"A novel approach for identification and measurement of hemoglobin adducts with 1, 2, 3, 4‐diepoxybutane by liquid chromatography/electrospray ionisation mass …","translated_title":"","metadata":{"publisher":"Wiley Online Library","grobid_abstract":"The metabolic pathway of BD leads to the sequential formation of BMO, DEB and BDO-diol , and therefore in vivo several different covalent Hb-adducts can be","publication_date":{"day":1,"month":1,"year":2001,"errors":{}},"publication_name":"Rapid …","grobid_abstract_attachment_id":51026864},"translated_abstract":null,"internal_url":"https://www.academia.edu/1326593/A_novel_approach_for_identification_and_measurement_of_hemoglobin_adducts_with_1_2_3_4_diepoxybutane_by_liquid_chromatography_electrospray_ionisation_mass_","translated_internal_url":"","created_at":"2012-02-01T17:24:34.205-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":455266,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":13005039,"work_id":1326593,"tagging_user_id":455266,"tagged_user_id":36993140,"co_author_invite_id":null,"email":"n***o@unina2.it","affiliation":"Università della Campania Luigi Vanvitelli","display_order":0,"name":"Nicola Sannolo","title":"A novel approach for identification and measurement of hemoglobin adducts with 1, 2, 3, 4‐diepoxybutane by liquid chromatography/electrospray ionisation mass …"},{"id":13126959,"work_id":1326593,"tagging_user_id":455266,"tagged_user_id":289263208,"co_author_invite_id":1318798,"email":"f***i@unina.it","display_order":4194304,"name":"Pasquale Ferranti","title":"A novel approach for identification and measurement of hemoglobin adducts with 1, 2, 3, 4‐diepoxybutane by liquid chromatography/electrospray ionisation mass …"},{"id":13126960,"work_id":1326593,"tagging_user_id":455266,"tagged_user_id":36754615,"co_author_invite_id":null,"email":"l***o@uniba.it","display_order":6291456,"name":"Leonardo Soleo","title":"A novel approach for identification and measurement of hemoglobin adducts with 1, 2, 3, 4‐diepoxybutane by liquid chromatography/electrospray ionisation mass …"},{"id":13126961,"work_id":1326593,"tagging_user_id":455266,"tagged_user_id":44465197,"co_author_invite_id":1505964,"email":"c***a@unina.it","display_order":7340032,"name":"Simonetta Caira","title":"A novel approach for identification and measurement of hemoglobin adducts with 1, 2, 3, 4‐diepoxybutane by liquid chromatography/electrospray ionisation mass …"},{"id":18133370,"work_id":1326593,"tagging_user_id":455266,"tagged_user_id":37198082,"co_author_invite_id":null,"email":"n***a@unina2.it","display_order":7864320,"name":"N. Miraglia","title":"A novel approach for identification and measurement of hemoglobin adducts with 1, 2, 3, 4‐diepoxybutane by liquid chromatography/electrospray ionisation mass …"},{"id":18133478,"work_id":1326593,"tagging_user_id":455266,"tagged_user_id":41164279,"co_author_invite_id":null,"email":"m***e@isa.cnr.it","display_order":8126464,"name":"Gianfranco Mamone","title":"A novel approach for identification and measurement of hemoglobin adducts with 1, 2, 3, 4‐diepoxybutane by liquid chromatography/electrospray ionisation mass …"},{"id":18133489,"work_id":1326593,"tagging_user_id":455266,"tagged_user_id":null,"co_author_invite_id":1787103,"email":"g***i@isa.cnr.it","display_order":8257536,"name":"Gabriella Pocsfalvi","title":"A novel approach for identification and measurement of hemoglobin adducts with 1, 2, 3, 4‐diepoxybutane by liquid chromatography/electrospray ionisation mass …"}],"downloadable_attachments":[{"id":51026864,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/51026864/thumbnails/1.jpg","file_name":"rcm.26320161223-16399-5d0wea.pdf","download_url":"https://www.academia.edu/attachments/51026864/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"A_novel_approach_for_identification_and.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/51026864/rcm.26320161223-16399-5d0wea-libre.pdf?1482485555=\u0026response-content-disposition=attachment%3B+filename%3DA_novel_approach_for_identification_and.pdf\u0026Expires=1732833882\u0026Signature=hRhNMDSAB3gVnTWJgxnAJgGoAvpeRWvGhnDUCjempC3AEYmbaOkRks~qJ3qOEzRZOB2-xG~Tk-MlbihG8tzqi4xC1OORal98RxtMi9HNTkw1MXJMMMt-NGqLVwGoVSMPVCk432~VjcR8xJgeXHx~udzUsiCwrPw9u5z5WI0ASKlcuMMETIX44LebwGzcVaosdPCY-ea4~ewNBSkW5D2xdc08qHG2F94jsqFJEmg0-GpXQ7sE1ttvCxzJPyPq9qr93fBIAVNGxendxP3Sc8RstMfgY9if2~HyShgNSQZuwNq1gNeeSDK2kXVV2MtU379GQuCEHT3XiyU3wAKfyPNAeA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"A_novel_approach_for_identification_and_measurement_of_hemoglobin_adducts_with_1_2_3_4_diepoxybutane_by_liquid_chromatography_electrospray_ionisation_mass_","translated_slug":"","page_count":14,"language":"en","content_type":"Work","owner":{"id":455266,"first_name":"Antonio","middle_initials":null,"last_name":"Malorni","page_name":"AntonioMalorni","domain_name":"unina","created_at":"2011-05-26T04:11:01.121-07:00","display_name":"Antonio Malorni","url":"https://unina.academia.edu/AntonioMalorni"},"attachments":[{"id":51026864,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/51026864/thumbnails/1.jpg","file_name":"rcm.26320161223-16399-5d0wea.pdf","download_url":"https://www.academia.edu/attachments/51026864/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"A_novel_approach_for_identification_and.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/51026864/rcm.26320161223-16399-5d0wea-libre.pdf?1482485555=\u0026response-content-disposition=attachment%3B+filename%3DA_novel_approach_for_identification_and.pdf\u0026Expires=1732833882\u0026Signature=hRhNMDSAB3gVnTWJgxnAJgGoAvpeRWvGhnDUCjempC3AEYmbaOkRks~qJ3qOEzRZOB2-xG~Tk-MlbihG8tzqi4xC1OORal98RxtMi9HNTkw1MXJMMMt-NGqLVwGoVSMPVCk432~VjcR8xJgeXHx~udzUsiCwrPw9u5z5WI0ASKlcuMMETIX44LebwGzcVaosdPCY-ea4~ewNBSkW5D2xdc08qHG2F94jsqFJEmg0-GpXQ7sE1ttvCxzJPyPq9qr93fBIAVNGxendxP3Sc8RstMfgY9if2~HyShgNSQZuwNq1gNeeSDK2kXVV2MtU379GQuCEHT3XiyU3wAKfyPNAeA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":400,"name":"Earth Sciences","url":"https://www.academia.edu/Documents/in/Earth_Sciences"},{"id":5769,"name":"Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Mass_Spectrometry"},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences"},{"id":151086,"name":"Peptides","url":"https://www.academia.edu/Documents/in/Peptides"},{"id":163275,"name":"Tandem Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Tandem_Mass_Spectrometry"},{"id":167158,"name":"Trypsin","url":"https://www.academia.edu/Documents/in/Trypsin"},{"id":246560,"name":"High Pressure Liquid Chromatography","url":"https://www.academia.edu/Documents/in/High_Pressure_Liquid_Chromatography"},{"id":260118,"name":"CHEMICAL SCIENCES","url":"https://www.academia.edu/Documents/in/CHEMICAL_SCIENCES"},{"id":326380,"name":"Liquid Chromatography / Electrospray Ionization Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Liquid_Chromatography_Electrospray_Ionization_Mass_Spectrometry"},{"id":398287,"name":"Liquid Chromatography","url":"https://www.academia.edu/Documents/in/Liquid_Chromatography"},{"id":664186,"name":"Alkylation","url":"https://www.academia.edu/Documents/in/Alkylation"},{"id":1311261,"name":"Hemoglobins","url":"https://www.academia.edu/Documents/in/Hemoglobins"},{"id":1485193,"name":"Rapid","url":"https://www.academia.edu/Documents/in/Rapid"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17402706"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17402706/Interaction_between_combustion_generated_organic_nanoparticles_and_biological_systems_In_vitro_study_of_cell_toxicity_and_apoptosis_in_human_keratinocytes"><img alt="Research paper thumbnail of Interaction between combustion-generated organic nanoparticles and biological systems: In vitro study of cell toxicity and apoptosis in human keratinocytes" class="work-thumbnail" src="https://attachments.academia-assets.com/39487935/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17402706/Interaction_between_combustion_generated_organic_nanoparticles_and_biological_systems_In_vitro_study_of_cell_toxicity_and_apoptosis_in_human_keratinocytes">Interaction between combustion-generated organic nanoparticles and biological systems: In vitro study of cell toxicity and apoptosis in human keratinocytes</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/PaolaPedata">Paola Pedata</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/patriziaminutolo">patrizia minutolo</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://unina2.academia.edu/NicolaSannolo">Nicola Sannolo</a></span></div><div class="wp-workCard_item"><span>Nanotoxicology</span><span>, 2012</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="42fb2877d28c694637524f5fd051e17b" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":39487935,"asset_id":17402706,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/39487935/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17402706"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17402706"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17402706; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17402706]").text(description); $(".js-view-count[data-work-id=17402706]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17402706; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17402706']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17402706, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "42fb2877d28c694637524f5fd051e17b" } } $('.js-work-strip[data-work-id=17402706]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17402706,"title":"Interaction between combustion-generated organic nanoparticles and biological systems: In vitro study of cell toxicity and apoptosis in human keratinocytes","translated_title":"","metadata":{"publication_date":{"day":null,"month":null,"year":2012,"errors":{}},"publication_name":"Nanotoxicology"},"translated_abstract":null,"internal_url":"https://www.academia.edu/17402706/Interaction_between_combustion_generated_organic_nanoparticles_and_biological_systems_In_vitro_study_of_cell_toxicity_and_apoptosis_in_human_keratinocytes","translated_internal_url":"","created_at":"2015-10-28T02:29:10.099-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":37126197,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":8131153,"work_id":17402706,"tagging_user_id":37126197,"tagged_user_id":38332080,"co_author_invite_id":444112,"email":"p***f@unina.it","display_order":0,"name":"Raffaele Porta","title":"Interaction between combustion-generated organic nanoparticles and biological systems: In vitro study of cell toxicity and apoptosis in human keratinocytes"},{"id":8131159,"work_id":17402706,"tagging_user_id":37126197,"tagged_user_id":31501796,"co_author_invite_id":1816707,"email":"p***8@gmail.com","display_order":4194304,"name":"patrizia minutolo","title":"Interaction between combustion-generated organic nanoparticles and biological systems: In vitro study of cell toxicity and apoptosis in human keratinocytes"},{"id":8131161,"work_id":17402706,"tagging_user_id":37126197,"tagged_user_id":null,"co_author_invite_id":1816709,"email":"m***o@st.com","display_order":6291456,"name":"Maria Napolitano","title":"Interaction between combustion-generated organic nanoparticles and biological systems: In vitro study of cell toxicity and apoptosis in human keratinocytes"},{"id":8131162,"work_id":17402706,"tagging_user_id":37126197,"tagged_user_id":null,"co_author_invite_id":1816710,"email":"l***o@yahoo.com","display_order":7340032,"name":"Lee Sgro","title":"Interaction between combustion-generated organic nanoparticles and biological systems: In vitro study of cell toxicity and apoptosis in human keratinocytes"},{"id":8131166,"work_id":17402706,"tagging_user_id":37126197,"tagged_user_id":36993140,"co_author_invite_id":null,"email":"n***o@unina2.it","affiliation":"Università della Campania Luigi Vanvitelli","display_order":7864320,"name":"Nicola Sannolo","title":"Interaction between combustion-generated organic nanoparticles and biological systems: In vitro study of cell toxicity and apoptosis in human keratinocytes"}],"downloadable_attachments":[{"id":39487935,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39487935/thumbnails/1.jpg","file_name":"Interaction_between_combustion-generated20151028-28426-1s6lzcw.pdf","download_url":"https://www.academia.edu/attachments/39487935/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Interaction_between_combustion_generated.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39487935/Interaction_between_combustion-generated20151028-28426-1s6lzcw-libre.pdf?1446032657=\u0026response-content-disposition=attachment%3B+filename%3DInteraction_between_combustion_generated.pdf\u0026Expires=1732833882\u0026Signature=RHgTEbOAtOAzKP-25-73gaETaKq90hmEgkkyK-LOuhXp71yu~Irn6WXVZ39novZwOgKqampzB8JD~Uet3J34m2yelbMK8Ch2nra556muGFd5Ob0BQBsOlr4ij~WNi7b~h5yZ7ZVIvbbcwnS2KBl~4jWfNlFeqMTzt09FO~qog2JK2G621QQ2r0i02pJQJBDCkFsuTwEOopJtFKZopTmHyR2AG~-Cvd925OYYseQpKoN3gZOFVeLSAQblQzljjlHdrv0pnPJkgX3NWG35QtSt0Au0FJnBoo0vDY3bmaQSImx08OT4GvpLRxT658SGUbWMSsENfvO~8NVW8d55LSiyvw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Interaction_between_combustion_generated_organic_nanoparticles_and_biological_systems_In_vitro_study_of_cell_toxicity_and_apoptosis_in_human_keratinocytes","translated_slug":"","page_count":18,"language":"en","content_type":"Work","owner":{"id":37126197,"first_name":"Paola","middle_initials":null,"last_name":"Pedata","page_name":"PaolaPedata","domain_name":"independent","created_at":"2015-10-28T02:28:26.614-07:00","display_name":"Paola Pedata","url":"https://independent.academia.edu/PaolaPedata"},"attachments":[{"id":39487935,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39487935/thumbnails/1.jpg","file_name":"Interaction_between_combustion-generated20151028-28426-1s6lzcw.pdf","download_url":"https://www.academia.edu/attachments/39487935/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Interaction_between_combustion_generated.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39487935/Interaction_between_combustion-generated20151028-28426-1s6lzcw-libre.pdf?1446032657=\u0026response-content-disposition=attachment%3B+filename%3DInteraction_between_combustion_generated.pdf\u0026Expires=1732833882\u0026Signature=RHgTEbOAtOAzKP-25-73gaETaKq90hmEgkkyK-LOuhXp71yu~Irn6WXVZ39novZwOgKqampzB8JD~Uet3J34m2yelbMK8Ch2nra556muGFd5Ob0BQBsOlr4ij~WNi7b~h5yZ7ZVIvbbcwnS2KBl~4jWfNlFeqMTzt09FO~qog2JK2G621QQ2r0i02pJQJBDCkFsuTwEOopJtFKZopTmHyR2AG~-Cvd925OYYseQpKoN3gZOFVeLSAQblQzljjlHdrv0pnPJkgX3NWG35QtSt0Au0FJnBoo0vDY3bmaQSImx08OT4GvpLRxT658SGUbWMSsENfvO~8NVW8d55LSiyvw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":5303,"name":"Carbon","url":"https://www.academia.edu/Documents/in/Carbon"},{"id":13621,"name":"Nanoparticles","url":"https://www.academia.edu/Documents/in/Nanoparticles"},{"id":17733,"name":"Nanotechnology","url":"https://www.academia.edu/Documents/in/Nanotechnology"},{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis"},{"id":47402,"name":"Nanotoxicology","url":"https://www.academia.edu/Documents/in/Nanotoxicology"},{"id":48057,"name":"DNA","url":"https://www.academia.edu/Documents/in/DNA"},{"id":57808,"name":"Cell line","url":"https://www.academia.edu/Documents/in/Cell_line"},{"id":70552,"name":"Keratinocytes","url":"https://www.academia.edu/Documents/in/Keratinocytes"},{"id":518609,"name":"Particulate Matter","url":"https://www.academia.edu/Documents/in/Particulate_Matter"},{"id":666927,"name":"Toxicity Tests","url":"https://www.academia.edu/Documents/in/Toxicity_Tests"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17402705"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17402705/Epirubicin_permeation_of_personal_protective_equipment_can_induce_apoptosis_in_keratinocytes"><img alt="Research paper thumbnail of Epirubicin permeation of personal protective equipment can induce apoptosis in keratinocytes" class="work-thumbnail" src="https://attachments.academia-assets.com/39487981/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17402705/Epirubicin_permeation_of_personal_protective_equipment_can_induce_apoptosis_in_keratinocytes">Epirubicin permeation of personal protective equipment can induce apoptosis in keratinocytes</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/PaolaPedata">Paola Pedata</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://unina2.academia.edu/NicolaSannolo">Nicola Sannolo</a></span></div><div class="wp-workCard_item"><span>Journal of Exposure Science and Environmental Epidemiology</span><span>, 2012</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="14933f0c8a396490711541bccd385ac0" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":39487981,"asset_id":17402705,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/39487981/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17402705"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17402705"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17402705; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17402705]").text(description); $(".js-view-count[data-work-id=17402705]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17402705; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17402705']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17402705, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "14933f0c8a396490711541bccd385ac0" } } $('.js-work-strip[data-work-id=17402705]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17402705,"title":"Epirubicin permeation of personal protective equipment can induce apoptosis in keratinocytes","translated_title":"","metadata":{"grobid_abstract":"The present study investigated the epirubicin (EPI) permeability of various commercially available glove types, as well as toxicity mechanisms and effects on human keratinocyte cell line (HaCaT). Permeability experiments were carried out on various commercially available gloves, differing as regards material and thickness. Permeability was evaluated after different ''contact times'' and the influence of EPI solution's pH (acid and neutral) on permeability was also examined. Toxicity of EPI toward skin was tested by evaluating the effects of the drug on cell growth and apoptosis, by using an in vitro model based on cultured immortalized human keratinocytes. No permeation was detected in the case of EPI neutral solutions; in contrast, acid solutions were found to penetrate low thickness nitrile gloves. Obtained results also showed the induction of apoptosis in epithelial cells through the activation of intrinsic pathway p53-independent occurring even when cells are exposed at low drug concentration. EPI solution's pH influences the glove's permeability; once penetrated, EPI at concentrations lower than those able to penetrate the nitrile glove during the 8-h work-shift can cause apoptosis in epithelial cells. The findings reported here highly support the choice of either natural rubbers gloves or high thickness nitrile ones for preventing the occupational exposure to EPI Q2 .","publication_date":{"day":null,"month":null,"year":2012,"errors":{}},"publication_name":"Journal of Exposure Science and Environmental Epidemiology","grobid_abstract_attachment_id":39487981},"translated_abstract":null,"internal_url":"https://www.academia.edu/17402705/Epirubicin_permeation_of_personal_protective_equipment_can_induce_apoptosis_in_keratinocytes","translated_internal_url":"","created_at":"2015-10-28T02:29:09.989-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":37126197,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":8131137,"work_id":17402705,"tagging_user_id":37126197,"tagged_user_id":37198082,"co_author_invite_id":1787097,"email":"n***a@unina2.it","display_order":0,"name":"N. Miraglia","title":"Epirubicin permeation of personal protective equipment can induce apoptosis in keratinocytes"},{"id":8131142,"work_id":17402705,"tagging_user_id":37126197,"tagged_user_id":64980285,"co_author_invite_id":1816700,"email":"m***i@unifi.it","display_order":4194304,"name":"Maria Pace Pieri","title":"Epirubicin permeation of personal protective equipment can induce apoptosis in keratinocytes"},{"id":8131152,"work_id":17402705,"tagging_user_id":37126197,"tagged_user_id":38332080,"co_author_invite_id":444112,"email":"p***f@unina.it","display_order":6291456,"name":"Raffaele Porta","title":"Epirubicin permeation of personal protective equipment can induce apoptosis in keratinocytes"},{"id":8131154,"work_id":17402705,"tagging_user_id":37126197,"tagged_user_id":null,"co_author_invite_id":1816705,"email":"a***e@iade.pt","display_order":7340032,"name":"Angela Silvestre","title":"Epirubicin permeation of personal protective equipment can induce apoptosis in keratinocytes"},{"id":8131156,"work_id":17402705,"tagging_user_id":37126197,"tagged_user_id":37456612,"co_author_invite_id":1816706,"email":"a***a@unina.it","display_order":7864320,"name":"Antonio Acampora","title":"Epirubicin permeation of personal protective equipment can induce apoptosis in keratinocytes"},{"id":8131165,"work_id":17402705,"tagging_user_id":37126197,"tagged_user_id":36993140,"co_author_invite_id":null,"email":"n***o@unina2.it","affiliation":"Università della Campania Luigi Vanvitelli","display_order":8126464,"name":"Nicola Sannolo","title":"Epirubicin permeation of personal protective equipment can induce apoptosis in keratinocytes"}],"downloadable_attachments":[{"id":39487981,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39487981/thumbnails/1.jpg","file_name":"Epirubicin_permeation_of_personal_protec20151028-22222-1od0mkr.pdf","download_url":"https://www.academia.edu/attachments/39487981/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Epirubicin_permeation_of_personal_protec.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39487981/Epirubicin_permeation_of_personal_protec20151028-22222-1od0mkr-libre.pdf?1446032918=\u0026response-content-disposition=attachment%3B+filename%3DEpirubicin_permeation_of_personal_protec.pdf\u0026Expires=1732833882\u0026Signature=P43crSCB6gY3-HpIGSp-uu2N4DdCK7TCQf50Eq2y58Mf13b9FPOT1VGMoTfZ~3svEEVwbJ5RKYs9FzIWVsrX6sMErfvV4EKQj1yfR6xh1bMT88pgI5nXOPm8zT60SeT5Ai5rWZ-MvEOEtS2uka5qoIOw39CBGfHp7uTppGsVggrDq-3VoS-DGFeEDoGJTfO-f2Wc9ZFrKvsBbOq74eKHKHUGyyR7DhP9ML17tkpPwWhmjkfbc5rOK1UWtUC1TPv7OyCjm9b06qIuV94Xm-kAEvfWaQ9q~m~DNN8bRUujF5-378R~BHUjbZjKUMh-WeT3Lc2hpPSSm1dnKCfwCF04yw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Epirubicin_permeation_of_personal_protective_equipment_can_induce_apoptosis_in_keratinocytes","translated_slug":"","page_count":7,"language":"en","content_type":"Work","owner":{"id":37126197,"first_name":"Paola","middle_initials":null,"last_name":"Pedata","page_name":"PaolaPedata","domain_name":"independent","created_at":"2015-10-28T02:28:26.614-07:00","display_name":"Paola Pedata","url":"https://independent.academia.edu/PaolaPedata"},"attachments":[{"id":39487981,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39487981/thumbnails/1.jpg","file_name":"Epirubicin_permeation_of_personal_protec20151028-22222-1od0mkr.pdf","download_url":"https://www.academia.edu/attachments/39487981/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Epirubicin_permeation_of_personal_protec.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39487981/Epirubicin_permeation_of_personal_protec20151028-22222-1od0mkr-libre.pdf?1446032918=\u0026response-content-disposition=attachment%3B+filename%3DEpirubicin_permeation_of_personal_protec.pdf\u0026Expires=1732833882\u0026Signature=P43crSCB6gY3-HpIGSp-uu2N4DdCK7TCQf50Eq2y58Mf13b9FPOT1VGMoTfZ~3svEEVwbJ5RKYs9FzIWVsrX6sMErfvV4EKQj1yfR6xh1bMT88pgI5nXOPm8zT60SeT5Ai5rWZ-MvEOEtS2uka5qoIOw39CBGfHp7uTppGsVggrDq-3VoS-DGFeEDoGJTfO-f2Wc9ZFrKvsBbOq74eKHKHUGyyR7DhP9ML17tkpPwWhmjkfbc5rOK1UWtUC1TPv7OyCjm9b06qIuV94Xm-kAEvfWaQ9q~m~DNN8bRUujF5-378R~BHUjbZjKUMh-WeT3Lc2hpPSSm1dnKCfwCF04yw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis"},{"id":37834,"name":"Western blotting","url":"https://www.academia.edu/Documents/in/Western_blotting"},{"id":50841,"name":"Caspases","url":"https://www.academia.edu/Documents/in/Caspases"},{"id":57808,"name":"Cell line","url":"https://www.academia.edu/Documents/in/Cell_line"},{"id":58054,"name":"Environmental Sciences","url":"https://www.academia.edu/Documents/in/Environmental_Sciences"},{"id":70552,"name":"Keratinocytes","url":"https://www.academia.edu/Documents/in/Keratinocytes"},{"id":83972,"name":"Permeability","url":"https://www.academia.edu/Documents/in/Permeability"},{"id":260118,"name":"CHEMICAL SCIENCES","url":"https://www.academia.edu/Documents/in/CHEMICAL_SCIENCES"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17401919"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17401919/_Absorption_distribution_and_elimination_of_carbon_monoxide_"><img alt="Research paper thumbnail of [Absorption, distribution and elimination of carbon monoxide]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17401919/_Absorption_distribution_and_elimination_of_carbon_monoxide_">[Absorption, distribution and elimination of carbon monoxide]</a></div><div class="wp-workCard_item"><span>Archivio Monaldi per le malattie del torace</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17401919"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17401919"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17401919; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17401919]").text(description); $(".js-view-count[data-work-id=17401919]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17401919; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17401919']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17401919, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17401919]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17401919,"title":"[Absorption, distribution and elimination of carbon monoxide]","translated_title":"","metadata":{"publication_name":"Archivio Monaldi per le malattie del torace"},"translated_abstract":null,"internal_url":"https://www.academia.edu/17401919/_Absorption_distribution_and_elimination_of_carbon_monoxide_","translated_internal_url":"","created_at":"2015-10-28T02:14:15.550-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"_Absorption_distribution_and_elimination_of_carbon_monoxide_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":11801,"name":"Environmental Monitoring","url":"https://www.academia.edu/Documents/in/Environmental_Monitoring"},{"id":71905,"name":"Carbon Monoxide","url":"https://www.academia.edu/Documents/in/Carbon_Monoxide"},{"id":396914,"name":"Occupational Exposure","url":"https://www.academia.edu/Documents/in/Occupational_Exposure"},{"id":1311261,"name":"Hemoglobins","url":"https://www.academia.edu/Documents/in/Hemoglobins"},{"id":1341982,"name":"Carbon Monoxide Poisoning","url":"https://www.academia.edu/Documents/in/Carbon_Monoxide_Poisoning"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17401918"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/17401918/_Methods_of_screening_for_cystinuria_Proposed_use_of_thin_layer_chromatography_"><img alt="Research paper thumbnail of [Methods of screening for cystinuria. Proposed use of thin-layer chromatography]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/17401918/_Methods_of_screening_for_cystinuria_Proposed_use_of_thin_layer_chromatography_">[Methods of screening for cystinuria. Proposed use of thin-layer chromatography]</a></div><div class="wp-workCard_item"><span>La Pediatria</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17401918"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17401918"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17401918; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17401918]").text(description); $(".js-view-count[data-work-id=17401918]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17401918; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17401918']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17401918, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17401918]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17401918,"title":"[Methods of screening for cystinuria. Proposed use of thin-layer chromatography]","translated_title":"","metadata":{"publication_name":"La Pediatria"},"translated_abstract":null,"internal_url":"https://www.academia.edu/17401918/_Methods_of_screening_for_cystinuria_Proposed_use_of_thin_layer_chromatography_","translated_internal_url":"","created_at":"2015-10-28T02:14:15.426-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"_Methods_of_screening_for_cystinuria_Proposed_use_of_thin_layer_chromatography_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":295928,"name":"Amino Acids","url":"https://www.academia.edu/Documents/in/Amino_Acids"},{"id":888739,"name":"Quntitative Thin Layer Chromatography","url":"https://www.academia.edu/Documents/in/Quntitative_Thin_Layer_Chromatography"},{"id":1438730,"name":"Creatinine","url":"https://www.academia.edu/Documents/in/Creatinine"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17401917"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17401917/Indicatori_di_dose_biologicamente_efficace"><img alt="Research paper thumbnail of Indicatori di dose biologicamente efficace" class="work-thumbnail" src="https://attachments.academia-assets.com/39487527/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17401917/Indicatori_di_dose_biologicamente_efficace">Indicatori di dose biologicamente efficace</a></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="0653fe4bd2adbc01ee31b6f583140cf8" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":39487527,"asset_id":17401917,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/39487527/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17401917"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17401917"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17401917; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17401917]").text(description); $(".js-view-count[data-work-id=17401917]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17401917; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17401917']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17401917, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "0653fe4bd2adbc01ee31b6f583140cf8" } } $('.js-work-strip[data-work-id=17401917]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17401917,"title":"Indicatori di dose biologicamente efficace","translated_title":"","metadata":{},"translated_abstract":null,"internal_url":"https://www.academia.edu/17401917/Indicatori_di_dose_biologicamente_efficace","translated_internal_url":"","created_at":"2015-10-28T02:14:15.315-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":39487527,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39487527/thumbnails/1.jpg","file_name":"Indicatori_di_dose_biologicamente_effica20151028-29725-1jooopq.pdf","download_url":"https://www.academia.edu/attachments/39487527/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Indicatori_di_dose_biologicamente_effica.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39487527/Indicatori_di_dose_biologicamente_effica20151028-29725-1jooopq-libre.pdf?1446032701=\u0026response-content-disposition=attachment%3B+filename%3DIndicatori_di_dose_biologicamente_effica.pdf\u0026Expires=1732833882\u0026Signature=TO-EkMvj-J7rjpoAkHw6TjfBSmUg8DVOb6x6Ejnw5xrdAd9SEyMJu9ELgZ4ZsqNkRumK5S8MJdnmkRxAYa9SwsweWXrsrdq4rW~ZGxTktJeq8ChQe3nDj4plBqi~YgY7duZ9D9uRQq7A4W9F07tzThID8hK5v4NEf052KSC6ro7o5Dh28lhqZ4Hq3SLbctySfC-4N3ptjtZOC8s2GbYpX6MP2mHjI6pvvimLMufUCyObzTxtxpK8EdZz9qSDhgIdCthhNpczo6fiiHzmJIfROuyBkXdaTYr1ChStWurKcSp77qDbycvjFbRz7aKcrbVkLNjg1BN-pgOPmARfK3GDeg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Indicatori_di_dose_biologicamente_efficace","translated_slug":"","page_count":4,"language":"it","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[{"id":39487527,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39487527/thumbnails/1.jpg","file_name":"Indicatori_di_dose_biologicamente_effica20151028-29725-1jooopq.pdf","download_url":"https://www.academia.edu/attachments/39487527/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Indicatori_di_dose_biologicamente_effica.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39487527/Indicatori_di_dose_biologicamente_effica20151028-29725-1jooopq-libre.pdf?1446032701=\u0026response-content-disposition=attachment%3B+filename%3DIndicatori_di_dose_biologicamente_effica.pdf\u0026Expires=1732833882\u0026Signature=TO-EkMvj-J7rjpoAkHw6TjfBSmUg8DVOb6x6Ejnw5xrdAd9SEyMJu9ELgZ4ZsqNkRumK5S8MJdnmkRxAYa9SwsweWXrsrdq4rW~ZGxTktJeq8ChQe3nDj4plBqi~YgY7duZ9D9uRQq7A4W9F07tzThID8hK5v4NEf052KSC6ro7o5Dh28lhqZ4Hq3SLbctySfC-4N3ptjtZOC8s2GbYpX6MP2mHjI6pvvimLMufUCyObzTxtxpK8EdZz9qSDhgIdCthhNpczo6fiiHzmJIfROuyBkXdaTYr1ChStWurKcSp77qDbycvjFbRz7aKcrbVkLNjg1BN-pgOPmARfK3GDeg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17401916"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17401916/_Extraction_of_fecal_lipids_and_identification_of_hydroxystearic_acid_by_gas_chromatography_mass_spectrometry_GC_MS_"><img alt="Research paper thumbnail of [Extraction of fecal lipids and identification of hydroxystearic acid by gas chromatography-mass spectrometry (GC/MS)]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17401916/_Extraction_of_fecal_lipids_and_identification_of_hydroxystearic_acid_by_gas_chromatography_mass_spectrometry_GC_MS_">[Extraction of fecal lipids and identification of hydroxystearic acid by gas chromatography-mass spectrometry (GC/MS)]</a></div><div class="wp-workCard_item"><span>Bollettino della Società italiana di biologia sperimentale</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Fatty acids and hydroxy fatty acids in the intestine are of interest because of their cathartic p...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Fatty acids and hydroxy fatty acids in the intestine are of interest because of their cathartic properties. We describe a method for extraction of lipids from freeze dried homogenized stools and identification of the hydroxy stearic acid in the fecal lipids pattern by GC-MS. Recovery of 90-95 % shows the efficacy of extraction . Quantitative data of fecal hydroxy stearic acid excretion in some normal and chronic diarrhea affected children are reported.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17401916"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17401916"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17401916; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17401916]").text(description); $(".js-view-count[data-work-id=17401916]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17401916; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17401916']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17401916, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17401916]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17401916,"title":"[Extraction of fecal lipids and identification of hydroxystearic acid by gas chromatography-mass spectrometry (GC/MS)]","translated_title":"","metadata":{"abstract":"Fatty acids and hydroxy fatty acids in the intestine are of interest because of their cathartic properties. We describe a method for extraction of lipids from freeze dried homogenized stools and identification of the hydroxy stearic acid in the fecal lipids pattern by GC-MS. Recovery of 90-95 % shows the efficacy of extraction . Quantitative data of fecal hydroxy stearic acid excretion in some normal and chronic diarrhea affected children are reported.","publication_name":"Bollettino della Società italiana di biologia sperimentale"},"translated_abstract":"Fatty acids and hydroxy fatty acids in the intestine are of interest because of their cathartic properties. We describe a method for extraction of lipids from freeze dried homogenized stools and identification of the hydroxy stearic acid in the fecal lipids pattern by GC-MS. Recovery of 90-95 % shows the efficacy of extraction . Quantitative data of fecal hydroxy stearic acid excretion in some normal and chronic diarrhea affected children are reported.","internal_url":"https://www.academia.edu/17401916/_Extraction_of_fecal_lipids_and_identification_of_hydroxystearic_acid_by_gas_chromatography_mass_spectrometry_GC_MS_","translated_internal_url":"","created_at":"2015-10-28T02:14:15.205-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"_Extraction_of_fecal_lipids_and_identification_of_hydroxystearic_acid_by_gas_chromatography_mass_spectrometry_GC_MS_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":44259,"name":"Diarrhea","url":"https://www.academia.edu/Documents/in/Diarrhea"},{"id":52055,"name":"Lipids","url":"https://www.academia.edu/Documents/in/Lipids"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child"},{"id":97269,"name":"Chronic Disease","url":"https://www.academia.edu/Documents/in/Chronic_Disease"},{"id":469102,"name":"Feces","url":"https://www.academia.edu/Documents/in/Feces"},{"id":529560,"name":"Gas Chromatography/mass Spectrometry","url":"https://www.academia.edu/Documents/in/Gas_Chromatography_mass_Spectrometry"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17401915"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17401915/Gas_chromatographic_quantitation_of_breath_hydrogen_and_carbon_monoxide_for_clinical_investigation_in_adults_and_in_children"><img alt="Research paper thumbnail of Gas chromatographic quantitation of breath hydrogen and carbon monoxide for clinical investigation in adults and in children" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17401915/Gas_chromatographic_quantitation_of_breath_hydrogen_and_carbon_monoxide_for_clinical_investigation_in_adults_and_in_children">Gas chromatographic quantitation of breath hydrogen and carbon monoxide for clinical investigation in adults and in children</a></div><div class="wp-workCard_item"><span>Journal of chromatography</span><span>, Jan 9, 1983</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">A simple and suitable method of breath sampling and the gas chromatographic determination of H2 a...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">A simple and suitable method of breath sampling and the gas chromatographic determination of H2 and CO in breath of children as well as of adults are described. The analytical system allows the measurement of concentrations of H2 and CO as low as a few ppm. The proposed method of breath collection (tedlar bag with low resistance valve face mask) appears particularly useful for long storage purposes, because it eliminates the need for additional manipulations and the possible associated sample dilution. Normalization of H2 breath amounts to internal standard O2 to obtain reliable and precise measurements is particularly useful in non-collaborating patients whose observed H2 peak values increase by 15% after the correction. The overall procedure is fast, inexpensive and accurately recognizes adult or children lactose malabsorbers as well as subjects exposed even to low levels of CO.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17401915"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17401915"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17401915; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17401915]").text(description); $(".js-view-count[data-work-id=17401915]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17401915; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17401915']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17401915, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17401915]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17401915,"title":"Gas chromatographic quantitation of breath hydrogen and carbon monoxide for clinical investigation in adults and in children","translated_title":"","metadata":{"abstract":"A simple and suitable method of breath sampling and the gas chromatographic determination of H2 and CO in breath of children as well as of adults are described. The analytical system allows the measurement of concentrations of H2 and CO as low as a few ppm. The proposed method of breath collection (tedlar bag with low resistance valve face mask) appears particularly useful for long storage purposes, because it eliminates the need for additional manipulations and the possible associated sample dilution. Normalization of H2 breath amounts to internal standard O2 to obtain reliable and precise measurements is particularly useful in non-collaborating patients whose observed H2 peak values increase by 15% after the correction. The overall procedure is fast, inexpensive and accurately recognizes adult or children lactose malabsorbers as well as subjects exposed even to low levels of CO.","publication_date":{"day":9,"month":1,"year":1983,"errors":{}},"publication_name":"Journal of chromatography"},"translated_abstract":"A simple and suitable method of breath sampling and the gas chromatographic determination of H2 and CO in breath of children as well as of adults are described. The analytical system allows the measurement of concentrations of H2 and CO as low as a few ppm. The proposed method of breath collection (tedlar bag with low resistance valve face mask) appears particularly useful for long storage purposes, because it eliminates the need for additional manipulations and the possible associated sample dilution. Normalization of H2 breath amounts to internal standard O2 to obtain reliable and precise measurements is particularly useful in non-collaborating patients whose observed H2 peak values increase by 15% after the correction. The overall procedure is fast, inexpensive and accurately recognizes adult or children lactose malabsorbers as well as subjects exposed even to low levels of CO.","internal_url":"https://www.academia.edu/17401915/Gas_chromatographic_quantitation_of_breath_hydrogen_and_carbon_monoxide_for_clinical_investigation_in_adults_and_in_children","translated_internal_url":"","created_at":"2015-10-28T02:14:15.086-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Gas_chromatographic_quantitation_of_breath_hydrogen_and_carbon_monoxide_for_clinical_investigation_in_adults_and_in_children","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":48,"name":"Engineering","url":"https://www.academia.edu/Documents/in/Engineering"},{"id":923,"name":"Technology","url":"https://www.academia.edu/Documents/in/Technology"},{"id":3771,"name":"Hydrogen","url":"https://www.academia.edu/Documents/in/Hydrogen"},{"id":4656,"name":"Chromatography","url":"https://www.academia.edu/Documents/in/Chromatography"},{"id":6791,"name":"Aging","url":"https://www.academia.edu/Documents/in/Aging"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child"},{"id":71300,"name":"Blood Glucose","url":"https://www.academia.edu/Documents/in/Blood_Glucose"},{"id":71905,"name":"Carbon Monoxide","url":"https://www.academia.edu/Documents/in/Carbon_Monoxide"},{"id":75318,"name":"Smoking","url":"https://www.academia.edu/Documents/in/Smoking"},{"id":78534,"name":"Lactose intolerance","url":"https://www.academia.edu/Documents/in/Lactose_intolerance"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant"},{"id":166448,"name":"Gas Chromatography","url":"https://www.academia.edu/Documents/in/Gas_Chromatography"},{"id":260118,"name":"CHEMICAL SCIENCES","url":"https://www.academia.edu/Documents/in/CHEMICAL_SCIENCES"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17401914"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17401914/Mass_spectrometric_analysis_of_rat_hemoglobin_by_FAB_overlapping"><img alt="Research paper thumbnail of Mass spectrometric analysis of rat hemoglobin by FAB-overlapping" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17401914/Mass_spectrometric_analysis_of_rat_hemoglobin_by_FAB_overlapping">Mass spectrometric analysis of rat hemoglobin by FAB-overlapping</a></div><div class="wp-workCard_item"><span>International Journal of Biochemistry</span><span>, 1988</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">1. The globin chain components of Sprague-Dawley rat hemoglobin were obtained by reverse-phase HP...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">1. The globin chain components of Sprague-Dawley rat hemoglobin were obtained by reverse-phase HPLC which showed the presence of two alpha-chain and four beta-chains. 2. The accurate molecular weight of each globin chain was determined by means of electrospray mass spectrometry. Extensive mass spectrometric analysis on several enzymatic digests by fast atom bombardment mass spectrometry (FAB-overlapping) meant to determine the complete sequence of the alpha-major and of the four beta-globins. 3. The primary structure of the alpha-major globin was found in agreement with literature data (Garrick et al., 1975 Biochem. J. 149, 245-258; Chua et al., 1987). 4. Sequence analysis of the four beta-globin chains showed that amino acid differences are restricted to two protein portions: the region 22-25 and 123-125, the remaining portions of the molecule being unchanged in the four globins. Furthermore, all the amino acid replacements correspond to single point DNA mutations and (with the exception of the substitution Asp 22--&amp;gt;Asn in the beta 2-globin) involve uncharged substitutions.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17401914"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17401914"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17401914; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17401914]").text(description); $(".js-view-count[data-work-id=17401914]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17401914; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17401914']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17401914, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17401914]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17401914,"title":"Mass spectrometric analysis of rat hemoglobin by FAB-overlapping","translated_title":"","metadata":{"abstract":"1. The globin chain components of Sprague-Dawley rat hemoglobin were obtained by reverse-phase HPLC which showed the presence of two alpha-chain and four beta-chains. 2. The accurate molecular weight of each globin chain was determined by means of electrospray mass spectrometry. Extensive mass spectrometric analysis on several enzymatic digests by fast atom bombardment mass spectrometry (FAB-overlapping) meant to determine the complete sequence of the alpha-major and of the four beta-globins. 3. The primary structure of the alpha-major globin was found in agreement with literature data (Garrick et al., 1975 Biochem. J. 149, 245-258; Chua et al., 1987). 4. Sequence analysis of the four beta-globin chains showed that amino acid differences are restricted to two protein portions: the region 22-25 and 123-125, the remaining portions of the molecule being unchanged in the four globins. Furthermore, all the amino acid replacements correspond to single point DNA mutations and (with the exception of the substitution Asp 22--\u0026amp;gt;Asn in the beta 2-globin) involve uncharged substitutions.","publication_date":{"day":null,"month":null,"year":1988,"errors":{}},"publication_name":"International Journal of Biochemistry"},"translated_abstract":"1. The globin chain components of Sprague-Dawley rat hemoglobin were obtained by reverse-phase HPLC which showed the presence of two alpha-chain and four beta-chains. 2. The accurate molecular weight of each globin chain was determined by means of electrospray mass spectrometry. Extensive mass spectrometric analysis on several enzymatic digests by fast atom bombardment mass spectrometry (FAB-overlapping) meant to determine the complete sequence of the alpha-major and of the four beta-globins. 3. The primary structure of the alpha-major globin was found in agreement with literature data (Garrick et al., 1975 Biochem. J. 149, 245-258; Chua et al., 1987). 4. Sequence analysis of the four beta-globin chains showed that amino acid differences are restricted to two protein portions: the region 22-25 and 123-125, the remaining portions of the molecule being unchanged in the four globins. Furthermore, all the amino acid replacements correspond to single point DNA mutations and (with the exception of the substitution Asp 22--\u0026amp;gt;Asn in the beta 2-globin) involve uncharged substitutions.","internal_url":"https://www.academia.edu/17401914/Mass_spectrometric_analysis_of_rat_hemoglobin_by_FAB_overlapping","translated_internal_url":"","created_at":"2015-10-28T02:14:14.987-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Mass_spectrometric_analysis_of_rat_hemoglobin_by_FAB_overlapping","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry"},{"id":5769,"name":"Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Mass_Spectrometry"},{"id":246560,"name":"High Pressure Liquid Chromatography","url":"https://www.academia.edu/Documents/in/High_Pressure_Liquid_Chromatography"},{"id":375054,"name":"Rats","url":"https://www.academia.edu/Documents/in/Rats"},{"id":809881,"name":"Amino Acid Sequence","url":"https://www.academia.edu/Documents/in/Amino_Acid_Sequence"},{"id":1311261,"name":"Hemoglobins","url":"https://www.academia.edu/Documents/in/Hemoglobins"},{"id":1681026,"name":"Biochemistry and cell biology","url":"https://www.academia.edu/Documents/in/Biochemistry_and_cell_biology"},{"id":1900203,"name":"Hemolysis","url":"https://www.academia.edu/Documents/in/Hemolysis"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17401913"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17401913/Structural_analysis_of_styrene_oxide_haemoglobin_adducts_by_mass_spectrometry_identification_of_suitable_biomarkers_for_human_exposure_evaluation"><img alt="Research paper thumbnail of Structural analysis of styrene oxide/haemoglobin adducts by mass spectrometry: identification of suitable biomarkers for human exposure evaluation" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17401913/Structural_analysis_of_styrene_oxide_haemoglobin_adducts_by_mass_spectrometry_identification_of_suitable_biomarkers_for_human_exposure_evaluation">Structural analysis of styrene oxide/haemoglobin adducts by mass spectrometry: identification of suitable biomarkers for human exposure evaluation</a></div><div class="wp-workCard_item"><span>Rapid Communications in Mass Spectrometry</span><span>, 2002</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The structural characterisation of adducts formed by the in vitro reaction of haemoglobin (Hb) wi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The structural characterisation of adducts formed by the in vitro reaction of haemoglobin (Hb) with styrene oxide (SO), the most reactive metabolite of the industrial reagent styrene, was obtained by liquid chromatography/electrospray ionisation mass spectrometry (LC/ES-MS) analysis of modified tryptic peptides of human Hb chains. The reactive sites of human Hb towards SO were identified through characterisation of alkylated tryptic peptides by matrix-assisted laser desorption/ionisation with tandem mass spectrometry (MALDI-MS/MS). A procedure was set up based on this characterisation, allowing Hb modification to be assessed by monitoring SO/Hb adducts using HPLC with selected ion recording (SIR) mass spectrometry. By this methodology it was also possible to compare advantages and disadvantages of presently available strategies for the measurement of Hb adducts with SO. The results obtained could most plausibly lead to the optimisation of molecular dosimetry of SO adducts, and the analytical procedure described herein could be applied to the biological monitoring of styrene exposure in the workplace.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17401913"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17401913"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17401913; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17401913]").text(description); $(".js-view-count[data-work-id=17401913]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17401913; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17401913']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17401913, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17401913]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17401913,"title":"Structural analysis of styrene oxide/haemoglobin adducts by mass spectrometry: identification of suitable biomarkers for human exposure evaluation","translated_title":"","metadata":{"abstract":"The structural characterisation of adducts formed by the in vitro reaction of haemoglobin (Hb) with styrene oxide (SO), the most reactive metabolite of the industrial reagent styrene, was obtained by liquid chromatography/electrospray ionisation mass spectrometry (LC/ES-MS) analysis of modified tryptic peptides of human Hb chains. The reactive sites of human Hb towards SO were identified through characterisation of alkylated tryptic peptides by matrix-assisted laser desorption/ionisation with tandem mass spectrometry (MALDI-MS/MS). A procedure was set up based on this characterisation, allowing Hb modification to be assessed by monitoring SO/Hb adducts using HPLC with selected ion recording (SIR) mass spectrometry. By this methodology it was also possible to compare advantages and disadvantages of presently available strategies for the measurement of Hb adducts with SO. The results obtained could most plausibly lead to the optimisation of molecular dosimetry of SO adducts, and the analytical procedure described herein could be applied to the biological monitoring of styrene exposure in the workplace.","publication_date":{"day":null,"month":null,"year":2002,"errors":{}},"publication_name":"Rapid Communications in Mass Spectrometry"},"translated_abstract":"The structural characterisation of adducts formed by the in vitro reaction of haemoglobin (Hb) with styrene oxide (SO), the most reactive metabolite of the industrial reagent styrene, was obtained by liquid chromatography/electrospray ionisation mass spectrometry (LC/ES-MS) analysis of modified tryptic peptides of human Hb chains. The reactive sites of human Hb towards SO were identified through characterisation of alkylated tryptic peptides by matrix-assisted laser desorption/ionisation with tandem mass spectrometry (MALDI-MS/MS). A procedure was set up based on this characterisation, allowing Hb modification to be assessed by monitoring SO/Hb adducts using HPLC with selected ion recording (SIR) mass spectrometry. By this methodology it was also possible to compare advantages and disadvantages of presently available strategies for the measurement of Hb adducts with SO. The results obtained could most plausibly lead to the optimisation of molecular dosimetry of SO adducts, and the analytical procedure described herein could be applied to the biological monitoring of styrene exposure in the workplace.","internal_url":"https://www.academia.edu/17401913/Structural_analysis_of_styrene_oxide_haemoglobin_adducts_by_mass_spectrometry_identification_of_suitable_biomarkers_for_human_exposure_evaluation","translated_internal_url":"","created_at":"2015-10-28T02:14:14.895-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Structural_analysis_of_styrene_oxide_haemoglobin_adducts_by_mass_spectrometry_identification_of_suitable_biomarkers_for_human_exposure_evaluation","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":400,"name":"Earth Sciences","url":"https://www.academia.edu/Documents/in/Earth_Sciences"},{"id":5769,"name":"Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Mass_Spectrometry"},{"id":11801,"name":"Environmental Monitoring","url":"https://www.academia.edu/Documents/in/Environmental_Monitoring"},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences"},{"id":151086,"name":"Peptides","url":"https://www.academia.edu/Documents/in/Peptides"},{"id":184909,"name":"Structure Analysis","url":"https://www.academia.edu/Documents/in/Structure_Analysis"},{"id":184989,"name":"Carcinogens","url":"https://www.academia.edu/Documents/in/Carcinogens"},{"id":260118,"name":"CHEMICAL SCIENCES","url":"https://www.academia.edu/Documents/in/CHEMICAL_SCIENCES"},{"id":568482,"name":"Biological markers","url":"https://www.academia.edu/Documents/in/Biological_markers"},{"id":809881,"name":"Amino Acid Sequence","url":"https://www.academia.edu/Documents/in/Amino_Acid_Sequence"},{"id":1311261,"name":"Hemoglobins","url":"https://www.academia.edu/Documents/in/Hemoglobins"},{"id":1312021,"name":"Environmental Exposure","url":"https://www.academia.edu/Documents/in/Environmental_Exposure"},{"id":1485193,"name":"Rapid","url":"https://www.academia.edu/Documents/in/Rapid"},{"id":1724844,"name":"Molecular Structure","url":"https://www.academia.edu/Documents/in/Molecular_Structure"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17401912"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17401912/Rare_Association_of_Hyperglycinuria_and_Lenticonus_in_Two_Members_of_the_Same_Family"><img alt="Research paper thumbnail of Rare Association of Hyperglycinuria and Lenticonus in Two Members of the Same Family" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17401912/Rare_Association_of_Hyperglycinuria_and_Lenticonus_in_Two_Members_of_the_Same_Family">Rare Association of Hyperglycinuria and Lenticonus in Two Members of the Same Family</a></div><div class="wp-workCard_item"><span>Ophthalmologica</span><span>, 1979</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">2 cases of posterior lenticonus associated with hyperglycinuria without iminoaciduria, found in t...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">2 cases of posterior lenticonus associated with hyperglycinuria without iminoaciduria, found in the same family, were examined. After a review of the literature, the rarity of this association is stressed.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17401912"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17401912"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17401912; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17401912]").text(description); $(".js-view-count[data-work-id=17401912]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17401912; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17401912']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17401912, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17401912]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17401912,"title":"Rare Association of Hyperglycinuria and Lenticonus in Two Members of the Same Family","translated_title":"","metadata":{"abstract":"2 cases of posterior lenticonus associated with hyperglycinuria without iminoaciduria, found in the same family, were examined. After a review of the literature, the rarity of this association is stressed.","publication_date":{"day":null,"month":null,"year":1979,"errors":{}},"publication_name":"Ophthalmologica"},"translated_abstract":"2 cases of posterior lenticonus associated with hyperglycinuria without iminoaciduria, found in the same family, were examined. After a review of the literature, the rarity of this association is stressed.","internal_url":"https://www.academia.edu/17401912/Rare_Association_of_Hyperglycinuria_and_Lenticonus_in_Two_Members_of_the_Same_Family","translated_internal_url":"","created_at":"2015-10-28T02:14:14.795-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Rare_Association_of_Hyperglycinuria_and_Lenticonus_in_Two_Members_of_the_Same_Family","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":359001,"name":"Optometry and Ophthalmology","url":"https://www.academia.edu/Documents/in/Optometry_and_Ophthalmology"},{"id":712543,"name":"Glycine","url":"https://www.academia.edu/Documents/in/Glycine"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17401911"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/17401911/Determination_of_bromide_in_water_by_gas_chromatography"><img alt="Research paper thumbnail of Determination of bromide in water by gas chromatography" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/17401911/Determination_of_bromide_in_water_by_gas_chromatography">Determination of bromide in water by gas chromatography</a></div><div class="wp-workCard_item"><span>Journal of Chromatography A</span><span>, 1979</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17401911"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17401911"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17401911; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17401911]").text(description); $(".js-view-count[data-work-id=17401911]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17401911; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17401911']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17401911, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17401911]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17401911,"title":"Determination of bromide in water by gas chromatography","translated_title":"","metadata":{"publication_date":{"day":null,"month":null,"year":1979,"errors":{}},"publication_name":"Journal of Chromatography A"},"translated_abstract":null,"internal_url":"https://www.academia.edu/17401911/Determination_of_bromide_in_water_by_gas_chromatography","translated_internal_url":"","created_at":"2015-10-28T02:14:14.701-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Determination_of_bromide_in_water_by_gas_chromatography","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":48,"name":"Engineering","url":"https://www.academia.edu/Documents/in/Engineering"},{"id":923,"name":"Technology","url":"https://www.academia.edu/Documents/in/Technology"},{"id":260118,"name":"CHEMICAL SCIENCES","url":"https://www.academia.edu/Documents/in/CHEMICAL_SCIENCES"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17309284"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17309284/Mass_spectrometric_analysis_of_rat_hemoglobin_by_FAB_overlapping_Primary_structure_of_the_alpha_major_and_of_four_beta_constitutive_chains"><img alt="Research paper thumbnail of Mass spectrometric analysis of rat hemoglobin by FAB-overlapping. Primary structure of the alpha-major and of four beta constitutive chains" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17309284/Mass_spectrometric_analysis_of_rat_hemoglobin_by_FAB_overlapping_Primary_structure_of_the_alpha_major_and_of_four_beta_constitutive_chains">Mass spectrometric analysis of rat hemoglobin by FAB-overlapping. Primary structure of the alpha-major and of four beta constitutive chains</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://unina2.academia.edu/NicolaSannolo">Nicola Sannolo</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://unina.academia.edu/AntonioMalorni">Antonio Malorni</a></span></div><div class="wp-workCard_item"><span>International Journal of Biochemistry</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">1. The globin chain components of Sprague-Dawley rat hemoglobin were obtained by reverse-phase HP...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">1. The globin chain components of Sprague-Dawley rat hemoglobin were obtained by reverse-phase HPLC which showed the presence of two alpha-chain and four beta-chains. 2. The accurate molecular weight of each globin chain was determined by means of electrospray mass spectrometry. Extensive mass spectrometric analysis on several enzymatic digests by fast atom bombardment mass spectrometry (FAB-overlapping) meant to determine the complete sequence of the alpha-major and of the four beta-globins. 3. The primary structure of the alpha-major globin was found in agreement with literature data (Garrick et al., 1975 Biochem. J. 149, 245-258; Chua et al., 1987). 4. Sequence analysis of the four beta-globin chains showed that amino acid differences are restricted to two protein portions: the region 22-25 and 123-125, the remaining portions of the molecule being unchanged in the four globins. Furthermore, all the amino acid replacements correspond to single point DNA mutations and (with the exception of the substitution Asp 22--&amp;gt;Asn in the beta 2-globin) involve uncharged substitutions.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17309284"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17309284"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17309284; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17309284]").text(description); $(".js-view-count[data-work-id=17309284]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17309284; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17309284']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17309284, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17309284]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17309284,"title":"Mass spectrometric analysis of rat hemoglobin by FAB-overlapping. Primary structure of the alpha-major and of four beta constitutive chains","translated_title":"","metadata":{"abstract":"1. The globin chain components of Sprague-Dawley rat hemoglobin were obtained by reverse-phase HPLC which showed the presence of two alpha-chain and four beta-chains. 2. The accurate molecular weight of each globin chain was determined by means of electrospray mass spectrometry. Extensive mass spectrometric analysis on several enzymatic digests by fast atom bombardment mass spectrometry (FAB-overlapping) meant to determine the complete sequence of the alpha-major and of the four beta-globins. 3. The primary structure of the alpha-major globin was found in agreement with literature data (Garrick et al., 1975 Biochem. J. 149, 245-258; Chua et al., 1987). 4. Sequence analysis of the four beta-globin chains showed that amino acid differences are restricted to two protein portions: the region 22-25 and 123-125, the remaining portions of the molecule being unchanged in the four globins. Furthermore, all the amino acid replacements correspond to single point DNA mutations and (with the exception of the substitution Asp 22--\u0026amp;gt;Asn in the beta 2-globin) involve uncharged substitutions.","publication_name":"International Journal of Biochemistry"},"translated_abstract":"1. The globin chain components of Sprague-Dawley rat hemoglobin were obtained by reverse-phase HPLC which showed the presence of two alpha-chain and four beta-chains. 2. The accurate molecular weight of each globin chain was determined by means of electrospray mass spectrometry. Extensive mass spectrometric analysis on several enzymatic digests by fast atom bombardment mass spectrometry (FAB-overlapping) meant to determine the complete sequence of the alpha-major and of the four beta-globins. 3. The primary structure of the alpha-major globin was found in agreement with literature data (Garrick et al., 1975 Biochem. J. 149, 245-258; Chua et al., 1987). 4. Sequence analysis of the four beta-globin chains showed that amino acid differences are restricted to two protein portions: the region 22-25 and 123-125, the remaining portions of the molecule being unchanged in the four globins. Furthermore, all the amino acid replacements correspond to single point DNA mutations and (with the exception of the substitution Asp 22--\u0026amp;gt;Asn in the beta 2-globin) involve uncharged substitutions.","internal_url":"https://www.academia.edu/17309284/Mass_spectrometric_analysis_of_rat_hemoglobin_by_FAB_overlapping_Primary_structure_of_the_alpha_major_and_of_four_beta_constitutive_chains","translated_internal_url":"","created_at":"2015-10-26T08:49:25.773-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":8002756,"work_id":17309284,"tagging_user_id":36993140,"tagged_user_id":289263208,"co_author_invite_id":1318798,"email":"f***i@unina.it","display_order":0,"name":"Pasquale Ferranti","title":"Mass spectrometric analysis of rat hemoglobin by FAB-overlapping. Primary structure of the alpha-major and of four beta constitutive chains"},{"id":8002780,"work_id":17309284,"tagging_user_id":36993140,"tagged_user_id":455266,"co_author_invite_id":null,"email":"a***i@cnr.it","affiliation":"Università degli Studi di Napoli \"Federico II\"","display_order":4194304,"name":"Antonio Malorni","title":"Mass spectrometric analysis of rat hemoglobin by FAB-overlapping. Primary structure of the alpha-major and of four beta constitutive chains"}],"downloadable_attachments":[],"slug":"Mass_spectrometric_analysis_of_rat_hemoglobin_by_FAB_overlapping_Primary_structure_of_the_alpha_major_and_of_four_beta_constitutive_chains","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry"},{"id":5769,"name":"Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Mass_Spectrometry"},{"id":246560,"name":"High Pressure Liquid Chromatography","url":"https://www.academia.edu/Documents/in/High_Pressure_Liquid_Chromatography"},{"id":375054,"name":"Rats","url":"https://www.academia.edu/Documents/in/Rats"},{"id":809881,"name":"Amino Acid Sequence","url":"https://www.academia.edu/Documents/in/Amino_Acid_Sequence"},{"id":1311261,"name":"Hemoglobins","url":"https://www.academia.edu/Documents/in/Hemoglobins"},{"id":1681026,"name":"Biochemistry and cell biology","url":"https://www.academia.edu/Documents/in/Biochemistry_and_cell_biology"},{"id":1900203,"name":"Hemolysis","url":"https://www.academia.edu/Documents/in/Hemolysis"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17309283"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17309283/_Perception_of_alcoholism_risk_in_health_workers_medical_role_in_prevention_and_surveillance_"><img alt="Research paper thumbnail of [Perception of alcoholism risk in health workers: medical role in prevention and surveillance]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17309283/_Perception_of_alcoholism_risk_in_health_workers_medical_role_in_prevention_and_surveillance_">[Perception of alcoholism risk in health workers: medical role in prevention and surveillance]</a></div><div class="wp-workCard_item"><span>Giornale italiano di medicina del lavoro ed ergonomia</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">According to Italian laws (legge 125/01, art. 15, comma 1) about safety on workplaces, it&amp;#39...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">According to Italian laws (legge 125/01, art. 15, comma 1) about safety on workplaces, it&amp;#39;s forbidden alcohol drinking and taking for health workers (art. 8, comma 6, legge 5/06/2003 number 131) (e.g. anaesthesiology, surgery, radiology, nursing etc.). National alcoholism risk prevention program to assess number for year of accidents in health workplaces, is actually in progress leaded by Health Minister and Regional administration (e.g. Tuscany). Particularly, prevention program acts consist in comprehensive informations for health workers and their co- workers, about prevention and identification of alcoholism- related risks. To assess the size of alcohol problems in health workplaces, Occupational Health Medicine Institute of Second University of Naples is going to enrol 500 subjects (200 nursing students, 200 Specialist Registrars of different areas, 100 Consultants). Actually our population consists in 160 Specialist Registrars of different medical subjects (surgery, clinical and laboratory). To verify the importance of alcoholism risk perception, a not validated questionnaire was administrated. This original assessing instrument consists in 23 items with closed answers about demographic information, university, career, lifestyle, knowledge about rules taking alcoholic drinks. Results show a dangerous lack of information about alcohol health effects, even in Medical Specialist Registrars.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17309283"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17309283"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17309283; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17309283]").text(description); $(".js-view-count[data-work-id=17309283]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17309283; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17309283']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17309283, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17309283]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17309283,"title":"[Perception of alcoholism risk in health workers: medical role in prevention and surveillance]","translated_title":"","metadata":{"abstract":"According to Italian laws (legge 125/01, art. 15, comma 1) about safety on workplaces, it\u0026amp;#39;s forbidden alcohol drinking and taking for health workers (art. 8, comma 6, legge 5/06/2003 number 131) (e.g. anaesthesiology, surgery, radiology, nursing etc.). National alcoholism risk prevention program to assess number for year of accidents in health workplaces, is actually in progress leaded by Health Minister and Regional administration (e.g. Tuscany). Particularly, prevention program acts consist in comprehensive informations for health workers and their co- workers, about prevention and identification of alcoholism- related risks. To assess the size of alcohol problems in health workplaces, Occupational Health Medicine Institute of Second University of Naples is going to enrol 500 subjects (200 nursing students, 200 Specialist Registrars of different areas, 100 Consultants). Actually our population consists in 160 Specialist Registrars of different medical subjects (surgery, clinical and laboratory). To verify the importance of alcoholism risk perception, a not validated questionnaire was administrated. This original assessing instrument consists in 23 items with closed answers about demographic information, university, career, lifestyle, knowledge about rules taking alcoholic drinks. Results show a dangerous lack of information about alcohol health effects, even in Medical Specialist Registrars.","publication_name":"Giornale italiano di medicina del lavoro ed ergonomia"},"translated_abstract":"According to Italian laws (legge 125/01, art. 15, comma 1) about safety on workplaces, it\u0026amp;#39;s forbidden alcohol drinking and taking for health workers (art. 8, comma 6, legge 5/06/2003 number 131) (e.g. anaesthesiology, surgery, radiology, nursing etc.). National alcoholism risk prevention program to assess number for year of accidents in health workplaces, is actually in progress leaded by Health Minister and Regional administration (e.g. Tuscany). Particularly, prevention program acts consist in comprehensive informations for health workers and their co- workers, about prevention and identification of alcoholism- related risks. To assess the size of alcohol problems in health workplaces, Occupational Health Medicine Institute of Second University of Naples is going to enrol 500 subjects (200 nursing students, 200 Specialist Registrars of different areas, 100 Consultants). Actually our population consists in 160 Specialist Registrars of different medical subjects (surgery, clinical and laboratory). To verify the importance of alcoholism risk perception, a not validated questionnaire was administrated. This original assessing instrument consists in 23 items with closed answers about demographic information, university, career, lifestyle, knowledge about rules taking alcoholic drinks. Results show a dangerous lack of information about alcohol health effects, even in Medical Specialist Registrars.","internal_url":"https://www.academia.edu/17309283/_Perception_of_alcoholism_risk_in_health_workers_medical_role_in_prevention_and_surveillance_","translated_internal_url":"","created_at":"2015-10-26T08:49:25.467-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":8002744,"work_id":17309283,"tagging_user_id":36993140,"tagged_user_id":null,"co_author_invite_id":1787099,"email":"f***i@unina2.it","display_order":0,"name":"Francesco Liotti","title":"[Perception of alcoholism risk in health workers: medical role in prevention and surveillance]"},{"id":8002947,"work_id":17309283,"tagging_user_id":36993140,"tagged_user_id":null,"co_author_invite_id":195909,"email":"c***o@ausl.bologna.it","display_order":4194304,"name":"C. Di Stefano","title":"[Perception of alcoholism risk in health workers: medical role in prevention and surveillance]"},{"id":8002948,"work_id":17309283,"tagging_user_id":36993140,"tagged_user_id":null,"co_author_invite_id":1787149,"email":"m***a@libero.it","display_order":6291456,"name":"M. Peduto","title":"[Perception of alcoholism risk in health workers: medical role in prevention and surveillance]"},{"id":8002949,"work_id":17309283,"tagging_user_id":36993140,"tagged_user_id":null,"co_author_invite_id":1787150,"email":"g***o@unipv.it","display_order":7340032,"name":"M. Ruberto","title":"[Perception of alcoholism risk in health workers: medical role in prevention and surveillance]"},{"id":8002950,"work_id":17309283,"tagging_user_id":36993140,"tagged_user_id":null,"co_author_invite_id":1787151,"email":"a***l@unina2.it","display_order":7864320,"name":"A. Di Tella","title":"[Perception of alcoholism risk in health workers: medical role in prevention and surveillance]"}],"downloadable_attachments":[],"slug":"_Perception_of_alcoholism_risk_in_health_workers_medical_role_in_prevention_and_surveillance_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":91863,"name":"Alcoholism","url":"https://www.academia.edu/Documents/in/Alcoholism"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors"},{"id":327850,"name":"Questionnaires","url":"https://www.academia.edu/Documents/in/Questionnaires"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1"},{"id":1824236,"name":"Health Personnel","url":"https://www.academia.edu/Documents/in/Health_Personnel"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17309282"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17309282/Ultrafine_particles_and_effects_on_the_organism_Literature_review"><img alt="Research paper thumbnail of Ultrafine particles and effects on the organism: Literature review" class="work-thumbnail" src="https://attachments.academia-assets.com/39437950/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17309282/Ultrafine_particles_and_effects_on_the_organism_Literature_review">Ultrafine particles and effects on the organism: Literature review</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/PaolaPedata">Paola Pedata</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://unina2.academia.edu/NicolaSannolo">Nicola Sannolo</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/ElpidioGarzillo">Elpidio Garzillo</a></span></div><div class="wp-workCard_item"><span>Giornale italiano di medicina del lavoro ed ergonomia</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="5a7c3807119fe8eca81dfc27c793cd93" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":39437950,"asset_id":17309282,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/39437950/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17309282"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17309282"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17309282; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17309282]").text(description); $(".js-view-count[data-work-id=17309282]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17309282; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17309282']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17309282, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "5a7c3807119fe8eca81dfc27c793cd93" } } $('.js-work-strip[data-work-id=17309282]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17309282,"title":"Ultrafine particles and effects on the organism: Literature review","translated_title":"","metadata":{"grobid_abstract":"Negli ultimi anni, l'interesse della comunità scientifica internazionale nel campo della ricerca si è incentrato sullo studio degli effetti del particolato ultrafine sulla salute umana. Le particelle ultrafini (PM 0.1 : diametro aerodinamico medio inferiore a 0.1 µm) sono complesse miscele di sostanze organiche ed inorganiche, dotate di intrinseca tossicità. Le loro piccole dimensioni le rendono degne di particolare attenzione in quanto sono in grado di penetrare fino alle vie aeree più profonde, sfuggendo ai normali meccanismi di difesa polmonare, ed entrare nel circolo sanguigno (1-6).","publication_name":"Giornale italiano di medicina del lavoro ed ergonomia","grobid_abstract_attachment_id":39437950},"translated_abstract":null,"internal_url":"https://www.academia.edu/17309282/Ultrafine_particles_and_effects_on_the_organism_Literature_review","translated_internal_url":"","created_at":"2015-10-26T08:49:25.044-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":8002859,"work_id":17309282,"tagging_user_id":36993140,"tagged_user_id":37126197,"co_author_invite_id":1787121,"email":"p***a@unina2.it","display_order":0,"name":"Paola Pedata","title":"Ultrafine particles and effects on the organism: Literature review"},{"id":8002864,"work_id":17309282,"tagging_user_id":36993140,"tagged_user_id":37146778,"co_author_invite_id":1787122,"email":"e***o@gmail.com","display_order":4194304,"name":"Elpidio Garzillo","title":"Ultrafine particles and effects on the organism: Literature review"}],"downloadable_attachments":[{"id":39437950,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39437950/thumbnails/1.jpg","file_name":"Ultrafine_particles_and_effects_on_the_o20151026-32577-dp5awl.pdf","download_url":"https://www.academia.edu/attachments/39437950/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Ultrafine_particles_and_effects_on_the_o.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39437950/Ultrafine_particles_and_effects_on_the_o20151026-32577-dp5awl-libre.pdf?1445895570=\u0026response-content-disposition=attachment%3B+filename%3DUltrafine_particles_and_effects_on_the_o.pdf\u0026Expires=1732833882\u0026Signature=HymdBiQbkywUM9CfGQ5y~81sOJM-ZunDBHWQNs10mmTZHIJ81TJMaVXfO~h4uwF2OWaNLkwoshw0HdBCDgscStZISFA~Sws6lzGTXNy6xqPuHwx99FIg28gbZc3qqcRNx6ks4yp4mVTtw7BoMcG9iF3BTg2S~UJAp2cm6100gfCA6L9eNjMMqSVMy7De2qQ5kV4D3CITjsuoyUprxiY6kO5q7z2DQGLBihuACie93TB2R82zd8zFVBETkAm3gxA9C8FR7vws7uVdiCri-rxkKlDl3JQnbV9LUJplh91um0rg4aQ~aauFo99MkDIxsdKxFE~1r9lVGGpKkDFWZu-pAA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Ultrafine_particles_and_effects_on_the_organism_Literature_review","translated_slug":"","page_count":9,"language":"it","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[{"id":39437950,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39437950/thumbnails/1.jpg","file_name":"Ultrafine_particles_and_effects_on_the_o20151026-32577-dp5awl.pdf","download_url":"https://www.academia.edu/attachments/39437950/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Ultrafine_particles_and_effects_on_the_o.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39437950/Ultrafine_particles_and_effects_on_the_o20151026-32577-dp5awl-libre.pdf?1445895570=\u0026response-content-disposition=attachment%3B+filename%3DUltrafine_particles_and_effects_on_the_o.pdf\u0026Expires=1732833882\u0026Signature=HymdBiQbkywUM9CfGQ5y~81sOJM-ZunDBHWQNs10mmTZHIJ81TJMaVXfO~h4uwF2OWaNLkwoshw0HdBCDgscStZISFA~Sws6lzGTXNy6xqPuHwx99FIg28gbZc3qqcRNx6ks4yp4mVTtw7BoMcG9iF3BTg2S~UJAp2cm6100gfCA6L9eNjMMqSVMy7De2qQ5kV4D3CITjsuoyUprxiY6kO5q7z2DQGLBihuACie93TB2R82zd8zFVBETkAm3gxA9C8FR7vws7uVdiCri-rxkKlDl3JQnbV9LUJplh91um0rg4aQ~aauFo99MkDIxsdKxFE~1r9lVGGpKkDFWZu-pAA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17309281"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17309281/Biologically_effective_dose_biomarkers"><img alt="Research paper thumbnail of Biologically effective dose biomarkers" class="work-thumbnail" src="https://attachments.academia-assets.com/39437949/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17309281/Biologically_effective_dose_biomarkers">Biologically effective dose biomarkers</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/NMiraglia">N. Miraglia</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://unina2.academia.edu/NicolaSannolo">Nicola Sannolo</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/SilviaFustinoni">Silvia Fustinoni</a></span></div><div class="wp-workCard_item"><span>Giornale italiano di medicina del lavoro ed ergonomia</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="af78fea79498b6fd7e1491797ae6abf3" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":39437949,"asset_id":17309281,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/39437949/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17309281"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17309281"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17309281; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17309281]").text(description); $(".js-view-count[data-work-id=17309281]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17309281; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17309281']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17309281, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "af78fea79498b6fd7e1491797ae6abf3" } } $('.js-work-strip[data-work-id=17309281]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17309281,"title":"Biologically effective dose biomarkers","translated_title":"","metadata":{"publication_name":"Giornale italiano di medicina del lavoro ed ergonomia"},"translated_abstract":null,"internal_url":"https://www.academia.edu/17309281/Biologically_effective_dose_biomarkers","translated_internal_url":"","created_at":"2015-10-26T08:49:24.694-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":8002738,"work_id":17309281,"tagging_user_id":36993140,"tagged_user_id":37198082,"co_author_invite_id":1787097,"email":"n***a@unina2.it","display_order":0,"name":"N. Miraglia","title":"Biologically effective dose biomarkers"},{"id":8002944,"work_id":17309281,"tagging_user_id":36993140,"tagged_user_id":null,"co_author_invite_id":302786,"email":"d***g@arpa.puglia.it","display_order":4194304,"name":"G. Assennato","title":"Biologically effective dose biomarkers"},{"id":8002945,"work_id":17309281,"tagging_user_id":36993140,"tagged_user_id":null,"co_author_invite_id":313834,"email":"c***o@ux1.unipd.it","display_order":6291456,"name":"E. Clonfero","title":"Biologically effective dose biomarkers"},{"id":8002946,"work_id":17309281,"tagging_user_id":36993140,"tagged_user_id":48675815,"co_author_invite_id":496494,"email":"s***i@unimi.it","display_order":7340032,"name":"Silvia Fustinoni","title":"Biologically effective dose biomarkers"}],"downloadable_attachments":[{"id":39437949,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39437949/thumbnails/1.jpg","file_name":"Biologically_effective_dose_biomarkers20151026-32584-bfd6no.pdf","download_url":"https://www.academia.edu/attachments/39437949/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Biologically_effective_dose_biomarkers.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39437949/Biologically_effective_dose_biomarkers20151026-32584-bfd6no-libre.pdf?1445895570=\u0026response-content-disposition=attachment%3B+filename%3DBiologically_effective_dose_biomarkers.pdf\u0026Expires=1732833882\u0026Signature=JIRDizHJmGoiUnoMrRU7bYEjaTdmiDG7cinSdiM7vcrEyXlUHiNZJQoxxk3CaiiA8U63G0-ACwLVYEvcjzD0EfW4MEjVFBsc1vNrO1Ht3u~u82zJpPM~XWkaFdplrKN6tt~agaFVxjXhB7QgJeWFatp5tPacvf909fZNlMCUbosTmkLFVptU9DFcxQ1zkaZUrI3jA6Opc4Ew8DA9t5FmkyM1O0XtiEJgRSWV632T1HD9TZs5DicXQnvoERDWnszaBXt-kCIUB5xkRi4B4DOArhD0-~Qv8lVWeT6vm-~VikF0nJI~akSeM5uL72bU7L6MDHUMpjzSsNUuKdo3E9GAlg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Biologically_effective_dose_biomarkers","translated_slug":"","page_count":4,"language":"it","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[{"id":39437949,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39437949/thumbnails/1.jpg","file_name":"Biologically_effective_dose_biomarkers20151026-32584-bfd6no.pdf","download_url":"https://www.academia.edu/attachments/39437949/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Biologically_effective_dose_biomarkers.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39437949/Biologically_effective_dose_biomarkers20151026-32584-bfd6no-libre.pdf?1445895570=\u0026response-content-disposition=attachment%3B+filename%3DBiologically_effective_dose_biomarkers.pdf\u0026Expires=1732833882\u0026Signature=JIRDizHJmGoiUnoMrRU7bYEjaTdmiDG7cinSdiM7vcrEyXlUHiNZJQoxxk3CaiiA8U63G0-ACwLVYEvcjzD0EfW4MEjVFBsc1vNrO1Ht3u~u82zJpPM~XWkaFdplrKN6tt~agaFVxjXhB7QgJeWFatp5tPacvf909fZNlMCUbosTmkLFVptU9DFcxQ1zkaZUrI3jA6Opc4Ew8DA9t5FmkyM1O0XtiEJgRSWV632T1HD9TZs5DicXQnvoERDWnszaBXt-kCIUB5xkRi4B4DOArhD0-~Qv8lVWeT6vm-~VikF0nJI~akSeM5uL72bU7L6MDHUMpjzSsNUuKdo3E9GAlg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":9478,"name":"Diet","url":"https://www.academia.edu/Documents/in/Diet"},{"id":11801,"name":"Environmental Monitoring","url":"https://www.academia.edu/Documents/in/Environmental_Monitoring"},{"id":19870,"name":"Research","url":"https://www.academia.edu/Documents/in/Research"},{"id":75318,"name":"Smoking","url":"https://www.academia.edu/Documents/in/Smoking"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors"},{"id":396914,"name":"Occupational Exposure","url":"https://www.academia.edu/Documents/in/Occupational_Exposure"},{"id":432116,"name":"Xenobiotics","url":"https://www.academia.edu/Documents/in/Xenobiotics"},{"id":568482,"name":"Biological markers","url":"https://www.academia.edu/Documents/in/Biological_markers"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1"},{"id":962276,"name":"Occupational Diseases","url":"https://www.academia.edu/Documents/in/Occupational_Diseases"},{"id":1162913,"name":"Mutagens","url":"https://www.academia.edu/Documents/in/Mutagens"},{"id":1232430,"name":"Genetic Markers","url":"https://www.academia.edu/Documents/in/Genetic_Markers"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17309280"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17309280/Managment_of_tuberculosis_in_an_University_of_Campania"><img alt="Research paper thumbnail of Managment of tuberculosis in an University of Campania" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17309280/Managment_of_tuberculosis_in_an_University_of_Campania">Managment of tuberculosis in an University of Campania</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/ElpidioGarzillo">Elpidio Garzillo</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://unina2.academia.edu/NicolaSannolo">Nicola Sannolo</a></span></div><div class="wp-workCard_item"><span>Giornale italiano di medicina del lavoro ed ergonomia</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Tuberculosis (TBC) is an infectious disease with the highest mortality and morbidity by single pa...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Tuberculosis (TBC) is an infectious disease with the highest mortality and morbidity by single pathogen, affecting about one third of worldwide population. Although Mantoux test is the most used, IGRA (Interferon-gamma Release Assays) tests seem to give good results for presumptive diagnosis of active or latent tuberculosis. From June 2011 to June 2012 we made about 1,000 visits for TBC prevention among the exposed to biological risks of our University. The management of suspected latent or active tuberculosis infection was carried out in collaboration with the pulmonologist, assessing the risk of contagion among exposed or affected operators. Health surveillance protocol and judgements of suitability for specific task were made not only in consideration of worker health, but also considerating the possible risk for patients, since this disease is a major problem for public health.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17309280"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17309280"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17309280; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17309280]").text(description); $(".js-view-count[data-work-id=17309280]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17309280; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17309280']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17309280, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17309280]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17309280,"title":"Managment of tuberculosis in an University of Campania","translated_title":"","metadata":{"abstract":"Tuberculosis (TBC) is an infectious disease with the highest mortality and morbidity by single pathogen, affecting about one third of worldwide population. Although Mantoux test is the most used, IGRA (Interferon-gamma Release Assays) tests seem to give good results for presumptive diagnosis of active or latent tuberculosis. From June 2011 to June 2012 we made about 1,000 visits for TBC prevention among the exposed to biological risks of our University. The management of suspected latent or active tuberculosis infection was carried out in collaboration with the pulmonologist, assessing the risk of contagion among exposed or affected operators. Health surveillance protocol and judgements of suitability for specific task were made not only in consideration of worker health, but also considerating the possible risk for patients, since this disease is a major problem for public health.","publication_name":"Giornale italiano di medicina del lavoro ed ergonomia"},"translated_abstract":"Tuberculosis (TBC) is an infectious disease with the highest mortality and morbidity by single pathogen, affecting about one third of worldwide population. Although Mantoux test is the most used, IGRA (Interferon-gamma Release Assays) tests seem to give good results for presumptive diagnosis of active or latent tuberculosis. From June 2011 to June 2012 we made about 1,000 visits for TBC prevention among the exposed to biological risks of our University. The management of suspected latent or active tuberculosis infection was carried out in collaboration with the pulmonologist, assessing the risk of contagion among exposed or affected operators. Health surveillance protocol and judgements of suitability for specific task were made not only in consideration of worker health, but also considerating the possible risk for patients, since this disease is a major problem for public health.","internal_url":"https://www.academia.edu/17309280/Managment_of_tuberculosis_in_an_University_of_Campania","translated_internal_url":"","created_at":"2015-10-26T08:49:24.271-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":8002863,"work_id":17309280,"tagging_user_id":36993140,"tagged_user_id":37146778,"co_author_invite_id":1787122,"email":"e***o@gmail.com","display_order":0,"name":"Elpidio Garzillo","title":"Managment of tuberculosis in an University of Campania"},{"id":8002905,"work_id":17309280,"tagging_user_id":36993140,"tagged_user_id":16904222,"co_author_invite_id":null,"email":"m***n@alice.it","display_order":4194304,"name":"Maria Monaco","title":"Managment of tuberculosis in an University of Campania"}],"downloadable_attachments":[],"slug":"Managment_of_tuberculosis_in_an_University_of_Campania","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":45213,"name":"Italy","url":"https://www.academia.edu/Documents/in/Italy"},{"id":62235,"name":"Tuberculosis","url":"https://www.academia.edu/Documents/in/Tuberculosis"},{"id":159736,"name":"Universities","url":"https://www.academia.edu/Documents/in/Universities"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17309279"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17309279/Studio_dell_esposizione_a_solventi_nell_industria_della_gomma_e_della_plastica_attraverso_il_monitoraggio_ambientale_e_il_monitoraggio_biologico_Applicazione_delle_metodiche_messe_a_punto_e_validate_dal_Gruppo_di_Studio_INAIL_SUN_nel_triennio_2009_2012"><img alt="Research paper thumbnail of Studio dell’esposizione a solventi nell’industria della gomma e della plastica, attraverso il monitoraggio ambientale e il monitoraggio biologico. Applicazione delle metodiche messe a punto e validate dal Gruppo di Studio INAIL-SUN nel triennio 2009-2012" class="work-thumbnail" src="https://attachments.academia-assets.com/39437953/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17309279/Studio_dell_esposizione_a_solventi_nell_industria_della_gomma_e_della_plastica_attraverso_il_monitoraggio_ambientale_e_il_monitoraggio_biologico_Applicazione_delle_metodiche_messe_a_punto_e_validate_dal_Gruppo_di_Studio_INAIL_SUN_nel_triennio_2009_2012">Studio dell’esposizione a solventi nell’industria della gomma e della plastica, attraverso il monitoraggio ambientale e il monitoraggio biologico. Applicazione delle metodiche messe a punto e validate dal Gruppo di Studio INAIL-SUN nel triennio 2009-2012</a></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="3a7ff1aef0ae4be645543d8f2e3c9af7" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":39437953,"asset_id":17309279,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/39437953/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17309279"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17309279"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17309279; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17309279]").text(description); $(".js-view-count[data-work-id=17309279]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17309279; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17309279']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17309279, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "3a7ff1aef0ae4be645543d8f2e3c9af7" } } $('.js-work-strip[data-work-id=17309279]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17309279,"title":"Studio dell’esposizione a solventi nell’industria della gomma e della plastica, attraverso il monitoraggio ambientale e il monitoraggio biologico. Applicazione delle metodiche messe a punto e validate dal Gruppo di Studio INAIL-SUN nel triennio 2009-2012","translated_title":"","metadata":{},"translated_abstract":null,"internal_url":"https://www.academia.edu/17309279/Studio_dell_esposizione_a_solventi_nell_industria_della_gomma_e_della_plastica_attraverso_il_monitoraggio_ambientale_e_il_monitoraggio_biologico_Applicazione_delle_metodiche_messe_a_punto_e_validate_dal_Gruppo_di_Studio_INAIL_SUN_nel_triennio_2009_2012","translated_internal_url":"","created_at":"2015-10-26T08:49:23.594-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":8002886,"work_id":17309279,"tagging_user_id":36993140,"tagged_user_id":null,"co_author_invite_id":1787132,"email":"g***5@campus.unimib.it","display_order":0,"name":"Giuliana Genovese","title":"Studio dell’esposizione a solventi nell’industria della gomma e della plastica, attraverso il monitoraggio ambientale e il monitoraggio biologico. Applicazione delle metodiche messe a punto e validate dal Gruppo di Studio INAIL-SUN nel triennio 2009-2012"},{"id":8002928,"work_id":17309279,"tagging_user_id":36993140,"tagged_user_id":21283568,"co_author_invite_id":null,"email":"c***9@libero.it","display_order":4194304,"name":"Cinzia Novi","title":"Studio dell’esposizione a solventi nell’industria della gomma e della plastica, attraverso il monitoraggio ambientale e il monitoraggio biologico. Applicazione delle metodiche messe a punto e validate dal Gruppo di Studio INAIL-SUN nel triennio 2009-2012"},{"id":8002933,"work_id":17309279,"tagging_user_id":36993140,"tagged_user_id":12642481,"co_author_invite_id":null,"email":"r***5@gmail.com","display_order":6291456,"name":"Roberto D'angelo","title":"Studio dell’esposizione a solventi nell’industria della gomma e della plastica, attraverso il monitoraggio ambientale e il monitoraggio biologico. Applicazione delle metodiche messe a punto e validate dal Gruppo di Studio INAIL-SUN nel triennio 2009-2012"}],"downloadable_attachments":[{"id":39437953,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39437953/thumbnails/1.jpg","file_name":"Studio_dellesposizione_a_solventi_nellin20151026-32577-13q3k88.pdf","download_url":"https://www.academia.edu/attachments/39437953/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Studio_dell_esposizione_a_solventi_nell.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39437953/Studio_dellesposizione_a_solventi_nellin20151026-32577-13q3k88.pdf?1445891794=\u0026response-content-disposition=attachment%3B+filename%3DStudio_dell_esposizione_a_solventi_nell.pdf\u0026Expires=1732833882\u0026Signature=gdzJZQL9SWd8IuRVHSw-Ni2C36nUmufR~DJQZ~~fTo4EzbCTqGe0VdZb3C4~prwbL9DUNAPrnAsl8JdIvlV2pw1d6ZpOO0As5kuRa0buaD7pQq2AvfktKsZgl10JrKJ51lETzq-Ha3LPBz7jLm0fzCtdICtigFA8hkMZqxdkCnw9TMJXowJAOFsc-7WnG~-bZOlHR9ua6u23HarFqUDizuFJItYuhx8ZzGSJnwJQua483FgP3ZLRCL50iWMkQ~nTILeQfQC~hJgkmOLqxoWS9aJ33b15mmaRNQYS-Lk5S80IhwrW1Q5fJqO9j8Jd52pO1CuUXk8sDu5u5DTkCohYYg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Studio_dell_esposizione_a_solventi_nell_industria_della_gomma_e_della_plastica_attraverso_il_monitoraggio_ambientale_e_il_monitoraggio_biologico_Applicazione_delle_metodiche_messe_a_punto_e_validate_dal_Gruppo_di_Studio_INAIL_SUN_nel_triennio_2009_2012","translated_slug":"","page_count":5,"language":"it","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[{"id":39437953,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/39437953/thumbnails/1.jpg","file_name":"Studio_dellesposizione_a_solventi_nellin20151026-32577-13q3k88.pdf","download_url":"https://www.academia.edu/attachments/39437953/download_file?st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&st=MTczMjgzMDI4Miw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Studio_dell_esposizione_a_solventi_nell.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/39437953/Studio_dellesposizione_a_solventi_nellin20151026-32577-13q3k88.pdf?1445891794=\u0026response-content-disposition=attachment%3B+filename%3DStudio_dell_esposizione_a_solventi_nell.pdf\u0026Expires=1732833882\u0026Signature=gdzJZQL9SWd8IuRVHSw-Ni2C36nUmufR~DJQZ~~fTo4EzbCTqGe0VdZb3C4~prwbL9DUNAPrnAsl8JdIvlV2pw1d6ZpOO0As5kuRa0buaD7pQq2AvfktKsZgl10JrKJ51lETzq-Ha3LPBz7jLm0fzCtdICtigFA8hkMZqxdkCnw9TMJXowJAOFsc-7WnG~-bZOlHR9ua6u23HarFqUDizuFJItYuhx8ZzGSJnwJQua483FgP3ZLRCL50iWMkQ~nTILeQfQC~hJgkmOLqxoWS9aJ33b15mmaRNQYS-Lk5S80IhwrW1Q5fJqO9j8Jd52pO1CuUXk8sDu5u5DTkCohYYg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17309278"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17309278/Usefulness_and_limits_of_a_new_method_for_biochemical_screening_of_lysosomal_storage_diseases"><img alt="Research paper thumbnail of Usefulness and limits of a new method for biochemical screening of lysosomal storage diseases" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17309278/Usefulness_and_limits_of_a_new_method_for_biochemical_screening_of_lysosomal_storage_diseases">Usefulness and limits of a new method for biochemical screening of lysosomal storage diseases</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://unina2.academia.edu/NicolaSannolo">Nicola Sannolo</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/FFalco2">F. Falco</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://unina.academia.edu/PietroStrisciuglio">Pietro Strisciuglio</a></span></div><div class="wp-workCard_item"><span>Acta neurologica</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17309278"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17309278"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17309278; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17309278]").text(description); $(".js-view-count[data-work-id=17309278]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17309278; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='17309278']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 17309278, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=17309278]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":17309278,"title":"Usefulness and limits of a new method for biochemical screening of lysosomal storage diseases","translated_title":"","metadata":{"publication_name":"Acta neurologica"},"translated_abstract":null,"internal_url":"https://www.academia.edu/17309278/Usefulness_and_limits_of_a_new_method_for_biochemical_screening_of_lysosomal_storage_diseases","translated_internal_url":"","created_at":"2015-10-26T08:49:23.097-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":36993140,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":8002940,"work_id":17309278,"tagging_user_id":36993140,"tagged_user_id":53202663,"co_author_invite_id":1787147,"email":"d***o@tin.it","display_order":0,"name":"F. Falco","title":"Usefulness and limits of a new method for biochemical screening of lysosomal storage diseases"},{"id":8002941,"work_id":17309278,"tagging_user_id":36993140,"tagged_user_id":33059454,"co_author_invite_id":null,"email":"p***o@unina.it","affiliation":"Università degli Studi di Napoli \"Federico II\"","display_order":4194304,"name":"Pietro Strisciuglio","title":"Usefulness and limits of a new method for biochemical screening of lysosomal storage diseases"},{"id":8002942,"work_id":17309278,"tagging_user_id":36993140,"tagged_user_id":null,"co_author_invite_id":1787148,"email":"r***n@mail.elmundo.com.bo","display_order":6291456,"name":"P. Mundo","title":"Usefulness and limits of a new method for biochemical screening of lysosomal storage diseases"},{"id":8002943,"work_id":17309278,"tagging_user_id":36993140,"tagged_user_id":22901615,"co_author_invite_id":null,"email":"g***o@gmail.com","display_order":7340032,"name":"gian maro di domenico","title":"Usefulness and limits of a new method for biochemical screening of lysosomal storage diseases"}],"downloadable_attachments":[],"slug":"Usefulness_and_limits_of_a_new_method_for_biochemical_screening_of_lysosomal_storage_diseases","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":36993140,"first_name":"Nicola","middle_initials":null,"last_name":"Sannolo","page_name":"NicolaSannolo","domain_name":"unina2","created_at":"2015-10-26T08:29:18.139-07:00","display_name":"Nicola Sannolo","url":"https://unina2.academia.edu/NicolaSannolo"},"attachments":[],"research_interests":[{"id":23868,"name":"Intellectual Disability","url":"https://www.academia.edu/Documents/in/Intellectual_Disability"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":108568,"name":"Inborn errors of metabolism","url":"https://www.academia.edu/Documents/in/Inborn_errors_of_metabolism"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> </div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/google_contacts-0dfb882d836b94dbcb4a2d123d6933fc9533eda5be911641f20b4eb428429600.js"], function() { // from javascript_helper.rb $('.js-google-connect-button').click(function(e) { e.preventDefault(); GoogleContacts.authorize_and_show_contacts(); Aedu.Dismissibles.recordClickthrough("WowProfileImportContactsPrompt"); }); $('.js-update-biography-button').click(function(e) { e.preventDefault(); Aedu.Dismissibles.recordClickthrough("UpdateUserBiographyPrompt"); $.ajax({ url: $r.api_v0_profiles_update_about_path({ subdomain_param: 'api', about: "", }), type: 'PUT', success: function(response) { location.reload(); } }); }); $('.js-work-creator-button').click(function (e) { e.preventDefault(); window.location = $r.upload_funnel_document_path({ source: encodeURIComponent(""), }); }); $('.js-video-upload-button').click(function (e) { e.preventDefault(); window.location = $r.upload_funnel_video_path({ source: encodeURIComponent(""), }); }); $('.js-do-this-later-button').click(function() { $(this).closest('.js-profile-nag-panel').remove(); Aedu.Dismissibles.recordDismissal("WowProfileImportContactsPrompt"); }); $('.js-update-biography-do-this-later-button').click(function(){ $(this).closest('.js-profile-nag-panel').remove(); Aedu.Dismissibles.recordDismissal("UpdateUserBiographyPrompt"); }); $('.wow-profile-mentions-upsell--close').click(function(){ $('.wow-profile-mentions-upsell--panel').hide(); Aedu.Dismissibles.recordDismissal("WowProfileMentionsUpsell"); }); $('.wow-profile-mentions-upsell--button').click(function(){ Aedu.Dismissibles.recordClickthrough("WowProfileMentionsUpsell"); }); new WowProfile.SocialRedesignUserWorks({ initialWorksOffset: 20, allWorksOffset: 20, maxSections: 1 }) }); </script> </div></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile_edit-5ea339ee107c863779f560dd7275595239fed73f1a13d279d2b599a28c0ecd33.js","https://a.academia-assets.com/assets/add_coauthor-22174b608f9cb871d03443cafa7feac496fb50d7df2d66a53f5ee3c04ba67f53.js","https://a.academia-assets.com/assets/tab-dcac0130902f0cc2d8cb403714dd47454f11fc6fb0e99ae6a0827b06613abc20.js","https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js"], function() { // from javascript_helper.rb window.ae = window.ae || {}; window.ae.WowProfile = window.ae.WowProfile || {}; if(Aedu.User.current && Aedu.User.current.id === $viewedUser.id) { window.ae.WowProfile.current_user_edit = {}; new WowProfileEdit.EditUploadView({ el: '.js-edit-upload-button-wrapper', model: window.$current_user, }); new AddCoauthor.AddCoauthorsController(); } var userInfoView = new WowProfile.SocialRedesignUserInfo({ recaptcha_key: "6LdxlRMTAAAAADnu_zyLhLg0YF9uACwz78shpjJB" }); WowProfile.router = new WowProfile.Router({ userInfoView: userInfoView }); Backbone.history.start({ pushState: true, root: "/" + $viewedUser.page_name }); new WowProfile.UserWorksNav() }); </script> </div> <div class="bootstrap login"><div class="modal fade login-modal" id="login-modal"><div class="login-modal-dialog modal-dialog"><div class="modal-content"><div class="modal-header"><button class="close close" data-dismiss="modal" type="button"><span aria-hidden="true">×</span><span class="sr-only">Close</span></button><h4 class="modal-title text-center"><strong>Log In</strong></h4></div><div class="modal-body"><div class="row"><div class="col-xs-10 col-xs-offset-1"><button class="btn btn-fb btn-lg btn-block btn-v-center-content" id="login-facebook-oauth-button"><svg style="float: left; width: 19px; line-height: 1em; margin-right: .3em;" aria-hidden="true" focusable="false" data-prefix="fab" data-icon="facebook-square" class="svg-inline--fa fa-facebook-square fa-w-14" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 448 512"><path fill="currentColor" d="M400 32H48A48 48 0 0 0 0 80v352a48 48 0 0 0 48 48h137.25V327.69h-63V256h63v-54.64c0-62.15 37-96.48 93.67-96.48 27.14 0 55.52 4.84 55.52 4.84v61h-31.27c-30.81 0-40.42 19.12-40.42 38.73V256h68.78l-11 71.69h-57.78V480H400a48 48 0 0 0 48-48V80a48 48 0 0 0-48-48z"></path></svg><small><strong>Log in</strong> with <strong>Facebook</strong></small></button><br /><button class="btn btn-google btn-lg btn-block btn-v-center-content" id="login-google-oauth-button"><svg style="float: left; width: 22px; line-height: 1em; margin-right: .3em;" aria-hidden="true" focusable="false" data-prefix="fab" data-icon="google-plus" class="svg-inline--fa fa-google-plus fa-w-16" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M256,8C119.1,8,8,119.1,8,256S119.1,504,256,504,504,392.9,504,256,392.9,8,256,8ZM185.3,380a124,124,0,0,1,0-248c31.3,0,60.1,11,83,32.3l-33.6,32.6c-13.2-12.9-31.3-19.1-49.4-19.1-42.9,0-77.2,35.5-77.2,78.1S142.3,334,185.3,334c32.6,0,64.9-19.1,70.1-53.3H185.3V238.1H302.2a109.2,109.2,0,0,1,1.9,20.7c0,70.8-47.5,121.2-118.8,121.2ZM415.5,273.8v35.5H380V273.8H344.5V238.3H380V202.8h35.5v35.5h35.2v35.5Z"></path></svg><small><strong>Log in</strong> with <strong>Google</strong></small></button><br /><style type="text/css">.sign-in-with-apple-button { width: 100%; height: 52px; border-radius: 3px; border: 1px solid black; cursor: pointer; }</style><script src="https://appleid.cdn-apple.com/appleauth/static/jsapi/appleid/1/en_US/appleid.auth.js" type="text/javascript"></script><div class="sign-in-with-apple-button" data-border="false" data-color="white" id="appleid-signin"><span   ="Sign Up with Apple" class="u-fs11"></span></div><script>AppleID.auth.init({ clientId: 'edu.academia.applesignon', scope: 'name email', redirectURI: 'https://www.academia.edu/sessions', state: "a8209d2e6f819ea76a7d796bdb55579f4bec33d2d747d988a4989a6690d93c74", });</script><script>// Hacky way of checking if on fast loswp if (window.loswp == null) { (function() { const Google = window?.Aedu?.Auth?.OauthButton?.Login?.Google; const Facebook = window?.Aedu?.Auth?.OauthButton?.Login?.Facebook; if (Google) { new Google({ el: '#login-google-oauth-button', rememberMeCheckboxId: 'remember_me', track: null }); } if (Facebook) { new Facebook({ el: '#login-facebook-oauth-button', rememberMeCheckboxId: 'remember_me', track: null }); } })(); }</script></div></div></div><div class="modal-body"><div class="row"><div class="col-xs-10 col-xs-offset-1"><div class="hr-heading login-hr-heading"><span class="hr-heading-text">or</span></div></div></div></div><div class="modal-body"><div class="row"><div class="col-xs-10 col-xs-offset-1"><form class="js-login-form" action="https://www.academia.edu/sessions" accept-charset="UTF-8" method="post"><input name="utf8" type="hidden" value="✓" autocomplete="off" /><input type="hidden" name="authenticity_token" value="uP+mYAQBO+TbcSSF5hZjyak9DK/pSPrgu2vVE8XMBjLS9b3Y0mVL02O1vnEXoot9BQrcg0OMTdiDVXDfWx24Mg==" autocomplete="off" /><div class="form-group"><label class="control-label" for="login-modal-email-input" style="font-size: 14px;">Email</label><input class="form-control" id="login-modal-email-input" name="login" type="email" /></div><div class="form-group"><label class="control-label" for="login-modal-password-input" style="font-size: 14px;">Password</label><input class="form-control" id="login-modal-password-input" name="password" type="password" /></div><input type="hidden" name="post_login_redirect_url" id="post_login_redirect_url" value="https://unina2.academia.edu/NicolaSannolo" autocomplete="off" /><div class="checkbox"><label><input type="checkbox" name="remember_me" id="remember_me" value="1" checked="checked" /><small style="font-size: 12px; margin-top: 2px; display: inline-block;">Remember me on this computer</small></label></div><br><input type="submit" name="commit" value="Log In" class="btn btn-primary btn-block btn-lg js-login-submit" data-disable-with="Log In" /></br></form><script>typeof window?.Aedu?.recaptchaManagedForm === 'function' && window.Aedu.recaptchaManagedForm( document.querySelector('.js-login-form'), document.querySelector('.js-login-submit') );</script><small style="font-size: 12px;"><br />or <a data-target="#login-modal-reset-password-container" data-toggle="collapse" href="javascript:void(0)">reset password</a></small><div class="collapse" id="login-modal-reset-password-container"><br /><div class="well margin-0x"><form class="js-password-reset-form" action="https://www.academia.edu/reset_password" accept-charset="UTF-8" method="post"><input name="utf8" type="hidden" value="✓" autocomplete="off" /><input type="hidden" name="authenticity_token" value="+n280f1N3utcCWrfZzagmkxzHadmy8gjAqe4YBbwDlmQd6dpKymu3OTN8CuWgkgu4ETNi8wPfxs6mR2siCGwWQ==" autocomplete="off" /><p>Enter the email address you signed up with and we'll email you a reset link.</p><div class="form-group"><input class="form-control" name="email" type="email" /></div><script src="https://recaptcha.net/recaptcha/api.js" async defer></script> <script> var invisibleRecaptchaSubmit = function () { var closestForm = function (ele) { var curEle = ele.parentNode; while (curEle.nodeName !== 'FORM' && curEle.nodeName !== 'BODY'){ curEle = curEle.parentNode; } return curEle.nodeName === 'FORM' ? curEle : null }; var eles = document.getElementsByClassName('g-recaptcha'); if (eles.length > 0) { var form = closestForm(eles[0]); if (form) { form.submit(); } } }; </script> <input type="submit" data-sitekey="6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj" data-callback="invisibleRecaptchaSubmit" class="g-recaptcha btn btn-primary btn-block" value="Email me a link" value=""/> </form></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/collapse-45805421cf446ca5adf7aaa1935b08a3a8d1d9a6cc5d91a62a2a3a00b20b3e6a.js"], function() { // from javascript_helper.rb $("#login-modal-reset-password-container").on("shown.bs.collapse", function() { $(this).find("input[type=email]").focus(); }); }); </script> </div></div></div><div class="modal-footer"><div class="text-center"><small style="font-size: 12px;">Need an account? <a rel="nofollow" href="https://www.academia.edu/signup">Click here to sign up</a></small></div></div></div></div></div></div><script>// If we are on subdomain or non-bootstrapped page, redirect to login page instead of showing modal (function(){ if (typeof $ === 'undefined') return; var host = window.location.hostname; if ((host === $domain || host === "www."+$domain) && (typeof $().modal === 'function')) { $("#nav_log_in").click(function(e) { // Don't follow the link and open the modal e.preventDefault(); $("#login-modal").on('shown.bs.modal', function() { $(this).find("#login-modal-email-input").focus() }).modal('show'); }); } })()</script> <div class="bootstrap" id="footer"><div class="footer-content clearfix text-center padding-top-7x" style="width:100%;"><ul class="footer-links-secondary footer-links-wide list-inline margin-bottom-1x"><li><a href="https://www.academia.edu/about">About</a></li><li><a href="https://www.academia.edu/press">Press</a></li><li><a rel="nofollow" href="https://medium.com/academia">Blog</a></li><li><a href="https://www.academia.edu/documents">Papers</a></li><li><a href="https://www.academia.edu/topics">Topics</a></li><li><a href="https://www.academia.edu/journals">Academia.edu Journals</a></li><li><a rel="nofollow" href="https://www.academia.edu/hiring"><svg style="width: 13px; height: 13px;" aria-hidden="true" focusable="false" data-prefix="fas" data-icon="briefcase" class="svg-inline--fa fa-briefcase fa-w-16" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M320 336c0 8.84-7.16 16-16 16h-96c-8.84 0-16-7.16-16-16v-48H0v144c0 25.6 22.4 48 48 48h416c25.6 0 48-22.4 48-48V288H320v48zm144-208h-80V80c0-25.6-22.4-48-48-48H176c-25.6 0-48 22.4-48 48v48H48c-25.6 0-48 22.4-48 48v80h512v-80c0-25.6-22.4-48-48-48zm-144 0H192V96h128v32z"></path></svg> <strong>We're Hiring!</strong></a></li><li><a rel="nofollow" href="https://support.academia.edu/"><svg style="width: 12px; height: 12px;" aria-hidden="true" focusable="false" data-prefix="fas" data-icon="question-circle" class="svg-inline--fa fa-question-circle fa-w-16" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M504 256c0 136.997-111.043 248-248 248S8 392.997 8 256C8 119.083 119.043 8 256 8s248 111.083 248 248zM262.655 90c-54.497 0-89.255 22.957-116.549 63.758-3.536 5.286-2.353 12.415 2.715 16.258l34.699 26.31c5.205 3.947 12.621 3.008 16.665-2.122 17.864-22.658 30.113-35.797 57.303-35.797 20.429 0 45.698 13.148 45.698 32.958 0 14.976-12.363 22.667-32.534 33.976C247.128 238.528 216 254.941 216 296v4c0 6.627 5.373 12 12 12h56c6.627 0 12-5.373 12-12v-1.333c0-28.462 83.186-29.647 83.186-106.667 0-58.002-60.165-102-116.531-102zM256 338c-25.365 0-46 20.635-46 46 0 25.364 20.635 46 46 46s46-20.636 46-46c0-25.365-20.635-46-46-46z"></path></svg> <strong>Help Center</strong></a></li></ul><ul class="footer-links-tertiary list-inline margin-bottom-1x"><li class="small">Find new research papers in:</li><li class="small"><a href="https://www.academia.edu/Documents/in/Physics">Physics</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Chemistry">Chemistry</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Biology">Biology</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Health_Sciences">Health Sciences</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Ecology">Ecology</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Earth_Sciences">Earth Sciences</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Cognitive_Science">Cognitive Science</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Mathematics">Mathematics</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Computer_Science">Computer Science</a></li></ul></div></div><div class="DesignSystem" id="credit" style="width:100%;"><ul class="u-pl0x footer-links-legal list-inline"><li><a rel="nofollow" href="https://www.academia.edu/terms">Terms</a></li><li><a rel="nofollow" href="https://www.academia.edu/privacy">Privacy</a></li><li><a rel="nofollow" href="https://www.academia.edu/copyright">Copyright</a></li><li>Academia ©2024</li></ul></div><script> //<![CDATA[ window.detect_gmtoffset = true; window.Academia && window.Academia.set_gmtoffset && Academia.set_gmtoffset('/gmtoffset'); //]]> </script> <div id='overlay_background'></div> <div id='bootstrap-modal-container' class='bootstrap'></div> <div id='ds-modal-container' class='bootstrap DesignSystem'></div> <div id='full-screen-modal'></div> </div> </body> </html>