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In chip- scale, the electroosmotic flow is more" /> <meta property="article:author" content="https://independent.academia.edu/rezavafaie" /> <meta name="description" content="High lamination in microchannel is one of the main challenges in Lab-On-a-Chip&#39;s components like micro total analyzer systems and any miniaturization of fluid channels intensify the viscose effects. In chip- scale, the electroosmotic flow is more" /> <title>(PDF) Numerical Simulation of a Novel Electroosmotic Micropump for Bio-MEMS Applications | reza vafaie - Academia.edu</title> <link rel="canonical" href="https://www.academia.edu/75382308/Numerical_Simulation_of_a_Novel_Electroosmotic_Micropump_for_Bio_MEMS_Applications" /> <script async src="https://www.googletagmanager.com/gtag/js?id=G-5VKX33P2DS"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-5VKX33P2DS', { cookie_domain: 'academia.edu', send_page_view: false, }); gtag('event', 'page_view', { 'controller': "single_work", 'action': "show", 'controller_action': 'single_work#show', 'logged_in': 'false', 'edge': 'unknown', // Send nil if there is no A/B test bucket, in case some records get logged // with missing data - that way we can distinguish between the two cases. // ab_test_bucket should be of the form <ab_test_name>:<bucket> 'ab_test_bucket': null, }) </script> <script> var $controller_name = 'single_work'; var $action_name = "show"; var $rails_env = 'production'; var $app_rev = '10e3dae8ffd20c8f5a4f7002303d92ad374c73ee'; var $domain = 'academia.edu'; var $app_host = "academia.edu"; var $asset_host = "academia-assets.com"; var $start_time = new Date().getTime(); var $recaptcha_key = "6LdxlRMTAAAAADnu_zyLhLg0YF9uACwz78shpjJB"; var $recaptcha_invisible_key = "6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj"; var $disableClientRecordHit = false; </script> <script> window.require = { config: function() { return function() {} } } </script> <script> window.Aedu = window.Aedu || {}; window.Aedu.hit_data = null; window.Aedu.serverRenderTime = new Date(1733263075000); window.Aedu.timeDifference = new Date().getTime() - 1733263075000; </script> <script type="application/ld+json">{"@context":"https://schema.org","@type":"ScholarlyArticle","abstract":"High lamination in microchannel is one of the main challenges in Lab-On-a-Chip\u0026amp;amp;#39;s components like micro total analyzer systems and any miniaturization of fluid channels intensify the viscose effects. In chip- scale, the electroosmotic flow is more efficient. Therefore, this study presents a MEMS-based low-voltage micropump for low-conductive biological samples and solutions, where twelve narrow miniaturized microchannels designed in one unit to efficiently using the electroosmotic effects which generated near the walls. Four microelectrodes are mounted in lateral sides of the microchannel and excited by low-voltage potential to generate pumping process inside the channel. We sweep the voltage amplitude and a linear variation of fluid velocity achieved by Finite-Element-Method (FEM) simulation. We obtain a net average velocity of 0.1 mm/s; by applying 2 V and -2 V to the electrodes. Therefore, the proposed low-voltage design is able to pumping the low-conductive biofluids for conv...","author":[{"@context":"https://schema.org","@type":"Person","name":"reza vafaie"}],"contributor":[],"dateCreated":"2022-04-03","dateModified":"2022-04-04","datePublished":"2014-01-01","headline":"Numerical Simulation of a Novel Electroosmotic Micropump for Bio-MEMS Applications","image":"https://attachments.academia-assets.com/83173292/thumbnails/1.jpg","inLanguage":"en","keywords":["Engineering","Sensors and transducers"],"publisher":{"@context":"https://schema.org","@type":"Organization","name":null},"sourceOrganization":[{"@context":"https://schema.org","@type":"EducationalOrganization","name":null}],"thumbnailUrl":"https://attachments.academia-assets.com/83173292/thumbnails/1.jpg","url":"https://www.academia.edu/75382308/Numerical_Simulation_of_a_Novel_Electroosmotic_Micropump_for_Bio_MEMS_Applications"}</script><link rel="stylesheet" media="all" 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Lab-On-a-Chip\u0026#39;s components like micro total analyzer systems and any miniaturization of fluid channels intensify the viscose effects. In chip- scale, the electroosmotic flow is more efficient. Therefore, this study presents a MEMS-based low-voltage micropump for low-conductive biological samples and solutions, where twelve narrow miniaturized microchannels designed in one unit to efficiently using the electroosmotic effects which generated near the walls. Four microelectrodes are mounted in lateral sides of the microchannel and excited by low-voltage potential to generate pumping process inside the channel. We sweep the voltage amplitude and a linear variation of fluid velocity achieved by Finite-Element-Method (FEM) simulation. We obtain a net average velocity of 0.1 mm/s; by applying 2 V and -2 V to the electrodes. Therefore, the proposed low-voltage design is able to pumping the low-conductive biofluids for conv...","publication_date":"2014,,"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Numerical Simulation of a Novel Electroosmotic Micropump for Bio-MEMS Applications","broadcastable":false,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [19775736]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container js-loswp-work-card"><div class="ds-work-card--cover"><div class="ds-work-cover--wrapper"><div class="ds-work-cover--container"><button class="ds-work-cover--clickable js-swp-download-button" data-signup-modal="{"location":"swp-splash-paper-cover","attachmentId":83173292,"attachmentType":"pdf"}"><img alt="First page of “Numerical Simulation of a Novel Electroosmotic Micropump for Bio-MEMS Applications”" class="ds-work-cover--cover-thumbnail" src="https://0.academia-photos.com/attachment_thumbnails/83173292/mini_magick20220403-12067-1b6uu1j.png?1649054547" /><img alt="PDF Icon" class="ds-work-cover--file-icon" src="//a.academia-assets.com/assets/single_work_splash/adobe.icon-574afd46eb6b03a77a153a647fb47e30546f9215c0ee6a25df597a779717f9ef.svg" /><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Numerical Simulation of a Novel Electroosmotic Micropump for Bio-MEMS Applications</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="19775736" href="https://independent.academia.edu/rezavafaie"><img alt="Profile image of reza vafaie" class="ds-work-card--author-avatar" src="https://0.academia-photos.com/19775736/5502035/6270072/s65_reza.vafaie.jpg" />reza vafaie</a></div><div class="ds-work-card--detail"><p class="ds-work-card--detail ds2-5-body-sm">2014</p><div class="ds-work-card--work-metadata"><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">visibility</span><p class="ds2-5-body-sm" id="work-metadata-view-count">…</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">description</span><p class="ds2-5-body-sm">7 pages</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">link</span><p class="ds2-5-body-sm">1 file</p></div></div><script>(async () => { const workId = 75382308; 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} }; // If the DOM is still loading, wait for it to be ready before updating the view count. if (document.readyState === "loading") { document.addEventListener('DOMContentLoaded', () => { updateViewCount(viewCount); }); // Otherwise, just update it immediately. } else { updateViewCount(viewCount); } })();</script></div><p class="ds-work-card--work-abstract ds-work-card--detail ds2-5-body-md">High lamination in microchannel is one of the main challenges in Lab-On-a-Chip&#39;s components like micro total analyzer systems and any miniaturization of fluid channels intensify the viscose effects. In chip- scale, the electroosmotic flow is more efficient. Therefore, this study presents a MEMS-based low-voltage micropump for low-conductive biological samples and solutions, where twelve narrow miniaturized microchannels designed in one unit to efficiently using the electroosmotic effects which generated near the walls. Four microelectrodes are mounted in lateral sides of the microchannel and excited by low-voltage potential to generate pumping process inside the channel. We sweep the voltage amplitude and a linear variation of fluid velocity achieved by Finite-Element-Method (FEM) simulation. We obtain a net average velocity of 0.1 mm/s; by applying 2 V and -2 V to the electrodes. Therefore, the proposed low-voltage design is able to pumping the low-conductive biofluids for conv...</p><div class="ds-work-card--button-container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--work-card","attachmentId":83173292,"attachmentType":"pdf","workUrl":"https://www.academia.edu/75382308/Numerical_Simulation_of_a_Novel_Electroosmotic_Micropump_for_Bio_MEMS_Applications"}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--work-card","attachmentId":83173292,"attachmentType":"pdf","workUrl":"https://www.academia.edu/75382308/Numerical_Simulation_of_a_Novel_Electroosmotic_Micropump_for_Bio_MEMS_Applications"}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div></div><div data-auto_select="false" data-client_id="331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b" data-doc_id="83173292" data-landing_url="https://www.academia.edu/75382308/Numerical_Simulation_of_a_Novel_Electroosmotic_Micropump_for_Bio_MEMS_Applications" data-login_uri="https://www.academia.edu/registrations/google_one_tap" data-moment_callback="onGoogleOneTapEvent" id="g_id_onload"></div><div class="ds-top-related-works--grid-container"><div class="ds-related-content--container ds-top-related-works--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="0" data-entity-id="70574104" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/70574104/Electroosmotically_induced_hydraulic_pumping_with_integrated_electrodes_on_microfluidic_devices">Electroosmotically induced hydraulic pumping with integrated electrodes on microfluidic devices</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="75464696" href="https://independent.academia.edu/JohnRamsey19">John Ramsey</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2001</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Electroosmotically induced hydraulic pumping with integrated electrodes on microfluidic devices","attachmentId":80269666,"attachmentType":"pdf","work_url":"https://www.academia.edu/70574104/Electroosmotically_induced_hydraulic_pumping_with_integrated_electrodes_on_microfluidic_devices","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/70574104/Electroosmotically_induced_hydraulic_pumping_with_integrated_electrodes_on_microfluidic_devices"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="1" data-entity-id="25657711" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/25657711/Microfluidic_pumping_routing_and_metering_by_contactless_metal_based_electro_osmosis">Microfluidic pumping, routing and metering by contactless metal-based electro-osmosis</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="49318559" href="https://johnshopkins.academia.edu/ZacharyGagnon">Zachary Gagnon</a></div><p class="ds-related-work--abstract ds2-5-body-sm">Over the past decade, many microfluidic platforms for fluid processing have been developed in order to perform on-chip fluidic manipulations. Many of these methods, however, require expensive and bulky external supporting equipment, which are not typically applicable for microsystems requiring portability. We have developed a new type of portable contactless metal electro-osmotic micropump capable of on-chip fluid pumping, routing and metering. The pump operates using two pairs of gallium metal electrodes, which are activated using an external voltage source, and separated from a main flow channel by a thin micron-scale PDMS membrane. The thin contactless membrane allows for field penetration and electro-osmotic (EO) flow within the microchannel, but eliminates electrode damage and sample contamination commonly associated with traditional DC electro-osmotic pumps that utilize electrodes in direct contact with the working fluid. The maximum flow rates and pressures generated by the pump using DI water as a working buffer are 10 nL min −1 and 30 Pa, respectively. With our current design, the maximum operational conductivity where fluid flow is observed is 0.1 mS cm −1. Due to the small size and simple fabrication procedure , multiple micropump units can be integrated into a single microfluidic device for automated on-chip routing and sample metering applications. We experimentally demonstrated the ability to quantify micropump electro-osmotic flowrate and pressure as a function of applied voltage, and developed a mathematical model capable of predicting the performance of a contactless micropump for a given external load and internal hydrodynamic microchannel resistance. Finally, we showed that by activating specific pumps within a microchannel network, our micropumps are capable of routing microchannel fluid flow and generating plugs of solute.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Microfluidic pumping, routing and metering by contactless metal-based electro-osmosis","attachmentId":45994635,"attachmentType":"pdf","work_url":"https://www.academia.edu/25657711/Microfluidic_pumping_routing_and_metering_by_contactless_metal_based_electro_osmosis","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/25657711/Microfluidic_pumping_routing_and_metering_by_contactless_metal_based_electro_osmosis"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="113056227" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/113056227/Development_of_a_microfluidic_electroosmosis_pump_on_a_chip_for_steady_and_continuous_fluid_delivery">Development of a microfluidic electroosmosis pump on a chip for steady and continuous fluid delivery</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="28985986" href="https://independent.academia.edu/Patr%C3%ADciaCanan%C3%A9">Patrícia Canané</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Biomedizinische Technik, 2022</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Development of a microfluidic electroosmosis pump on a chip for steady and continuous fluid delivery","attachmentId":110118881,"attachmentType":"pdf","work_url":"https://www.academia.edu/113056227/Development_of_a_microfluidic_electroosmosis_pump_on_a_chip_for_steady_and_continuous_fluid_delivery","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/113056227/Development_of_a_microfluidic_electroosmosis_pump_on_a_chip_for_steady_and_continuous_fluid_delivery"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="3" data-entity-id="20658827" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/20658827/Multiple_Open_Channel_Electroosmotic_Pumping_System_for_Microfluidic_Sample_Handling">Multiple Open-Channel Electroosmotic Pumping System for Microfluidic Sample Handling</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="20867" href="https://neu.academia.edu/BarryKarger">Barry Karger</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="5243830" href="https://vt.academia.edu/IulianaLazar">Iulia M Lazar</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Analytical Chemistry, 2002</p><p class="ds-related-work--abstract ds2-5-body-sm">The development of a novel, fully integrated, miniaturized pumping system for generation of pressure-driven flow in microfluidic platforms is described. The micropump, based on electroosmotic pumping principles, has a multiple open-channel configuration consisting of hundreds of parallel, small-diameter microchannels. Specifically, pumps with microchannels of 1-6 microm in depth, 4-50 mm in length, and an overall area of a few square millimeters, were constructed. Flow rates of 10-400 nL/min were generated in electric-field-free regions in a stable, reproducible and controllable manner. In addition, eluent gradients were created by simultaneously using two pumps. Pressures up to 80 psi were produced with the present pump configurations. The pump can be easily interfaced with other operational elements of a micrototal analysis system (micro-TAS) device with multiplexing capabilities. A new microfluidic valving system was also briefly evaluated in conjunction with these pumps. 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class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="110244450" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/110244450/Innovative_Design_and_Modeling_of_a_Micropump_A_Microfluidics_Application">Innovative Design and Modeling of a Micropump: A Microfluidics Application</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="58848439" href="https://independent.academia.edu/GilbertoP%C3%A9rezLechuga">Gilberto Pérez Lechuga</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2012</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" 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