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" 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id="RCAUserType" /> <input type="hidden" name="ctl00$RootHolder$UserId" id="UserId" /> <input type="hidden" name="ctl00$RootHolder$IsCurrentUser" id="IsCurrentUser" /> <div class="search-result-container cl"> <div class="search-centered cl"> <div class="search-result-center-container cl"> <div class="left-part"> <div id="RootHolder_ExportContainer" class="export-container"> <div class="dxbButton_MetropolisBlue DefaultButton-Oral dxbButtonSys dxbTSys" id="RootHolder_DownloadArticle" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxb"> <input id="RootHolder_DownloadArticle_I" class="dxb-hb" value="Download" type="button" name="ctl00$RootHolder$DownloadArticle" /><span class="dx-vam">Download</span> </div> </div><script id="dxss_1963926087" type="text/javascript">  </script> </div> <div class="mnavbar"> <table class="total-count-container cl"> <tr> <td> <a href="/" target="_blank" class="white-link">Total Articles</a> </td> </tr> </table> </div> <div class="mnavbox"> <label id="RootHolder_TotalCountText" class="total-count-text">780</label> <br /> <label style="font-size: 14px;">(from Reference Citation Analysis)</label> <div id="RootHolder_SearchArticlePDFContainer" style="padding-top: 1rem;"> <input name="ctl00$RootHolder$ArticlesWithPdf" type="checkbox" id="RootHolder_ArticlesWithPdf" class="ArticlesWithPdf" onclick="SearchArticleWithPDF();" /> <label for="ArticlesWithPdf">Article PDFs (143)</label> </div> <div id="RootHolder_SearchTCContainer" style="padding-top: 1rem;"> <input name="ctl00$RootHolder$ArticlesWithTC" type="checkbox" id="RootHolder_ArticlesWithTC" class="ArticlesWithTC" onclick="SearchArticleWithTC();" /> <label for="ArticlesWithTC">Cited by ≥ 1 (465)</label> </div> </div> <div class="mnavbar" id="SearchedNameTitle"> <div> Searched Name </div> </div> <div class="mnavbox" id="SearchedNameText"> <label id="RootHolder_SearchTermText" class="search-term-text">Carbon monoxide</label> </div> <div 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sortedby-list"> <li> <a href="javascript:SubmitSingleFacetSearch('create','6');">Today (<span id="indexCount6"></span>)</a> </li> <li> <a href="javascript:SubmitSingleFacetSearch('create','5');">Yesterday (<span id="indexCount5"></span>)</a> </li> <li> <a href="javascript:SubmitSingleFacetSearch('create','4');">This Week (<span id="indexCount4"></span>)</a> </li> <li> <a href="javascript:SubmitSingleFacetSearch('create','3');">Last Week (<span id="indexCount3"></span>)</a> </li> <li> <a href="javascript:SubmitSingleFacetSearch('create','2');">Current Month (<span id="indexCount2"></span>)</a> </li> <li> <a href="javascript:SubmitSingleFacetSearch('create','1');">Last Month (<span id="indexCount1"></span>)</a> </li> </ul> </div> <div id="journalFacetContainer"> <div class="mnavbar"> <div> Publication Titles </div> </div> <div class="mnavbox"> <div id="journalFacetItemContainer"> </div> <div class="refine-btn-container cl"> <a href="javascript:ShowResultItems('journal');" 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Red light-induced localized release of <span class="highlight-field">carbon monoxide</span> for alleviating postoperative cognitive dysfunction. <em class='incite-journal-name' onclick='ShowInCiteJournal(3556);'>Biomaterials</em> 2025;<b>312</b>:122744. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39106820' target='_blank'>39106820</a> DOI: <a href='https://dx.doi.org/10.1016/j.biomaterials.2024.122744' target='_blank'>10.1016/j.biomaterials.2024.122744</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.biomaterials.2024.122744','39106820', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(1);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(1);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(1);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.biomaterials.2024.122744' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3556);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 04/07/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/12/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/01/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 08/09/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv1" value="10.1016/j.biomaterials.2024.122744" /> <div style="display: none" id="articleAbstract1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Inflammation within the central nervous system (CNS), which may be triggered by surgical trauma, has been implicated as a significant factor contributing to postoperative cognitive dysfunction (POCD). The relationship between mitigating inflammation at peripheral surgical sites and its potential to attenuate the CNS inflammatory response, thereby easing POCD symptoms, remains uncertain. Notably, carbon monoxide (CO), a gasotransmitter, exhibits pronounced anti-inflammatory effects. Herein, we have developed carbon monoxide-releasing micelles (CORMs), a nanoparticle that safely and locally liberates CO upon exposure to 650 nm light irradiation. In a POCD mouse model, treatment with CORMs activated by light (CORMs + hv) markedly reduced the concentrations of interleukin (IL)-6, IL-1β, and tumor necrosis factor-alpha (TNF-α) in both the peripheral blood and the hippocampus, alongside a decrease in ionized calcium-binding adapter molecule 1 in the hippocampal CA1 region. Furthermore, CORMs + hv treatment diminished Evans blue extravasation, augmented the expression of tight junction proteins zonula occludens-1 and occludin, enhanced neurocognitive functions, and fostered fracture healing. Bioinformatics analysis and experimental validation has identified Htr1b and Trhr as potential key regulators in the neuroactive ligand-receptor interaction signaling pathway implicated in POCD. This work offers new perspectives on the mechanisms driving POCD and avenues for therapeutic intervention. </div> <a href="javascript:ShowArticleAbstract(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anti-inflammatory%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anti-inflammatory</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Blood-brain+barrier%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Blood-brain barrier</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postoperative+cognitive+dysfunction%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Postoperative cognitive dysfunction</a></li></ul> <a href="javascript:ShowArticleKeywords(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+Monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon Monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postoperative+Cognitive+Complications%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Postoperative Cognitive Complications/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postoperative+Cognitive+Complications%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Postoperative Cognitive Complications/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Light%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Light</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%2c+Inbred+C57BL%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice, Inbred C57BL</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nanoparticles%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nanoparticles/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Micelles%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Micelles</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Red+Light%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Red Light</a></li></ul> <a href="javascript:ShowArticleMeSH(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(1);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow2"> <td style="min-width: 40px; text-align: center;"> 2 </td> <td> <div id="citation2" class="article-citation"> <b>Cui Y</b>, Yang K, Guo C, Xia Z, Jiang B, Xue Y, Song B, Hu W, Zhang M, Wei Y, Zhang C, Zhang S, Fang J. <span class="highlight-field">Carbon monoxide</span> as a negative feedback mechanism on HIF-1α in the progression of metabolic-associated fatty liver disease. <em class='incite-journal-name' onclick='ShowInCiteJournal(168932);'>Nitric Oxide</em> 2024;<b>153</b>:1-12. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39369813' target='_blank'>39369813</a> DOI: <a href='https://dx.doi.org/10.1016/j.niox.2024.10.001' target='_blank'>10.1016/j.niox.2024.10.001</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.niox.2024.10.001','39369813', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(2);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(2);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(2);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.niox.2024.10.001' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(168932);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/24/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/01/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/03/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/08/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv2" value="10.1016/j.niox.2024.10.001" /> <div style="display: none" id="articleAbstract2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Metabolic-associated fatty liver disease (MAFLD) encompasses various chronic liver conditions, yet lacks approved drugs. Hypoxia-inducible factor-1α (HIF-1α) is pivotal in MAFLD development. Our prior research highlighted the efficacy of the nano-designed carbon monoxide (CO) donor, targeting HIF-1α in a mouse hepatic steatosis model. Given heme oxygenase-1 (HO-1, a major downstream molecule of HIF-1α) as the primary source of intrinsic CO, we hypothesized that upregulation of HO-1/CO, responsive to HIF-1α, forms a negative feedback loop regulating MAFLD progression. In this study, we explored the potential negative feedback mechanism of CO on HIF-1α and its downstream effects on MAFLD advancement. HIF-1α emerges early in hepatic steatosis induced by a high-fat (HF) diet, triggering increased HO-1 and inflammation. SMA/CORM2 effectively suppresses HIF-1α and steatosis progression when administered within the initial week of HF diet initiation but loses impact later. In adipose tissues, concurrent metabolic dysfunction and inflammation with HIF-1α activation suggest adipose tissue expansion initiates HF-induced steatosis, triggering hypoxia and liver inflammation. Notably, in an in vitro study using mouse hepatocytes treated with fatty acids, downregulating HO-1 intensified HIF-1α induction at moderate fatty acid concentrations. However, this effect diminished at high concentrations. These results suggest the HIF-1α-HO-1-CO axis as a feedback loop under physiological and mild pathological conditions. Excessive HIF-1α upregulation in pathological conditions overwhelms the CO feedback loop. Additional CO application effectively suppresses HIF-1α and disease progression, indicating potential application for MAFLD control. </div> <a href="javascript:ShowArticleAbstract(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22CO%e2%80%93HIF-1%ce%b1+axis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">CO–HIF-1α axis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Feedback+loop%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Feedback loop</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypoxia-inducible+factor-1%ce%b1%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypoxia-inducible factor-1α</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Metabolic-associated+fatty+liver+disease%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Metabolic-associated fatty liver disease</a></li></ul> <a href="javascript:ShowArticleKeywords(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypoxia-Inducible+Factor+1%2c+alpha+Subunit%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypoxia-Inducible Factor 1, alpha Subunit/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+Monoxide%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon Monoxide/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+Monoxide%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon Monoxide/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%2c+Inbred+C57BL%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice, Inbred C57BL</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Feedback%2c+Physiological%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Feedback, Physiological</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Non-alcoholic+Fatty+Liver+Disease%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Non-alcoholic Fatty Liver Disease/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Progression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Progression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Heme+Oxygenase-1%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Heme Oxygenase-1/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diet%2c+High-Fat%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diet, High-Fat/adverse effects</a></li></ul> <a href="javascript:ShowArticleMeSH(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(2);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow3"> <td style="min-width: 40px; text-align: center;"> 3 </td> <td> <div id="citation3" class="article-citation"> <b>Carvalho MC</b>, Gomez-Alvarez P, Jeffrey LC, Maher DT. Improving the measurement of nitrogen stable isotopes in organic materials containing high C:N ratios using a 5A molecular sieve column. <em class='incite-journal-name' onclick='ShowInCiteJournal(172069);'>MethodsX</em> 2024;<b>13</b>:102889. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39233750' target='_blank'>39233750</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11372605' target='_blank'>PMC11372605</a> DOI: <a href='https://dx.doi.org/10.1016/j.mex.2024.102889' target='_blank'>10.1016/j.mex.2024.102889</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.mex.2024.102889','39233750', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(3);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(3);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.mex.2024.102889' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="openf" onclick="OpenFigures('10.1016/j.mex.2024.102889');">Figures</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(172069);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/15/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/02/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/06/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv3" value="10.1016/j.mex.2024.102889" /> <div style="display: none" id="articleAbstract3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">The nitrogen stable isotope composition (δ15N) of plant materials has numerous applications. Plant materials like bark can have a very high C:N ratio. Incomplete C combustion in such samples interferes with the δ15N measurement due to CO production. We modified the standard setup for δ15N measurement using an elemental analyzer (EA) coupled to an isotope ratio mass spectrometer (IRMS) by incorporating a 5A molecular sieve column, which better separates N2 from CO. We compared this new modified setup and the standard one for the measurement of bark samples. Precision and accuracy for δ15N in standards with low C:N ratio were equivalent for the two methods. However, for bark the results obtained with the new method had better precision and accuracy than the standard method. Replicates are nevertheless recommended with the new method to ensure confidence in the results.•During elemental analysis, incomplete combustion of material with high C:N ratio can lead to CO formation, which interferes with δ15N IRMS measurements.•Here we use a 5A molsieve column to remove the CO interference in δ15N measurements Precision and accuracy on δ15N measurements of samples with high C content are significantly improved. </div> <a href="javascript:ShowArticleAbstract(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%225A+molecular+sieve%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">5A molecular sieve</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%225A+molsieve+for+%ce%b415N%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">5A molsieve for δ15N</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bark%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bark</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Elemental+analysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Elemental analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nitrogen%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nitrogen</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stable+isotopes%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stable isotopes</a></li></ul> <a href="javascript:ShowArticleKeywords(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(3);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow4"> <td style="min-width: 40px; text-align: center;"> 4 </td> <td> <div id="citation4" class="article-citation"> <b>Yao J</b>, Meng Q, Xu Q, Fu H, Xu H, Feng Q, Cao X, Zhou Y, Huang H, Bai C, Qiao R. A novel BN aromatic module modified near-infrared fluorescent probe for monitoring <span class="highlight-field">carbon monoxide</span>-releasing molecule CORM-3 in living cells and animals. <em class='incite-journal-name' onclick='ShowInCiteJournal(21752);'>Talanta</em> 2024;<b>280</b>:126734. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39173248' target='_blank'>39173248</a> DOI: <a href='https://dx.doi.org/10.1016/j.talanta.2024.126734' target='_blank'>10.1016/j.talanta.2024.126734</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.talanta.2024.126734','39173248', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(4);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(4);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(4);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.talanta.2024.126734' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(21752);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 04/27/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 06/15/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/18/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 08/24/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv4" value="10.1016/j.talanta.2024.126734" /> <div style="display: none" id="articleAbstract4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Carbon monoxide (CO), a significant gas transmitter, plays a vital role in the intricate functioning of living systems and is intimately linked to a variety of physiological and pathological processes. To comprehensively investigate CO within biological system, researchers have widely adopted CORM-3, a compound capable of releasing CO, which serves as a surrogate for CO. It aids in elucidating the physiological and pathological effects of CO within living organisms and can be employed as a therapeutic drug molecule. Therefore, the pivotal role of CORM-3 necessitates the development of effective probes that can facilitate the visualization and tracking of CORM-3 in living systems. However, creating fluorescent probes for real-time imaging of CORM-3 in living species has proven to be a persisting challenge that arises from factors such as background interference, light scattering and photoactivation. Herein, the BNDN fluorescent probe, a brand-new near-infrared is proposed. Remarkably, the BNDN probe offers several noteworthy advantages, including a substantial Stokes shift (201 nm), heightened sensitivity, exceptional selectivity, and an exceedingly low CORM-3 detection limit (0.7 ppb). Furthermore, the underlying sensing mechanism has been meticulously examined, revealing a process that revives the fluorophore by reducing the complex Cu2+ to Cu+. This distinctive NIR fluorescence "turn-on" character, coupled with its larger Stokes shift, holds great promise for achieving high resolution imaging. Most impressively, this innovative probe has demonstrated its efficacy in detecting exogenous CORM-3 in living animal. It is important to underscore that these endeavors mark a rare instance of a near-infrared probes successfully detecting exogenous CORM-3 in vivo. These exceptional outcomes highlighted the potential of BNDN as a highly promising new tool for in vivo detection of CORM-3. Considering the impressive imaging capabilities demonstrated by BNDN presented in this study, we anticipate that this tool may offer a compelling avenue for shedding light on the roles of CO in future research endeavors. </div> <a href="javascript:ShowArticleAbstract(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Boron-nitrogen+aromatics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Boron-nitrogen aromatics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mechanism+exploration%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mechanism exploration</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Near-infrared+fluorescent+probe%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Near-infrared fluorescent probe</a></li></ul> <a href="javascript:ShowArticleKeywords(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Fluorescent+Dyes%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Fluorescent Dyes/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+Monoxide%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon Monoxide/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Organometallic+Compounds%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Organometallic Compounds/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Optical+Imaging%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Optical Imaging/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Boranes%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Boranes/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Zebrafish%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Zebrafish</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Limit+of+Detection%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Limit of Detection</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22HeLa+Cells%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">HeLa Cells</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Infrared+Rays%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Infrared Rays</a></li></ul> <a href="javascript:ShowArticleMeSH(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(4);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow5"> <td style="min-width: 40px; text-align: center;"> 5 </td> <td> <div id="citation5" class="article-citation"> <b>Guo XJ</b>, Huang LY, Gong ST, Li M, Wang W, Chen J, Zhang YD, Lu X, Chen X, Luo L, Yang Y, Luo X, Qi SH. Peroxynitrite-Triggered <span class="highlight-field">Carbon Monoxide</span> Donor Improves Ischemic Stroke Outcome by Inhibiting Neuronal Apoptosis and Ferroptosis. <em class='incite-journal-name' onclick='ShowInCiteJournal(17033);'>Mol Neurobiol</em> 2024;<b>61</b>:10629-10644. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38767837' target='_blank'>38767837</a> DOI: <a href='https://dx.doi.org/10.1007/s12035-024-04238-w' target='_blank'>10.1007/s12035-024-04238-w</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/s12035-024-04238-w','38767837', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(5);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(5);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(5);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(5);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1007/s12035-024-04238-w' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(17033);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 10/19/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 04/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 05/22/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv5" value="10.1007/s12035-024-04238-w" /> <div style="display: none" id="articleAbstract5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Cerebral ischemia-reperfusion injury produces excessive reactive oxygen and nitrogen species, including superoxide, nitric oxide, and peroxynitrite (ONOO-). We recently developed a new ONOO--triggered metal-free carbon monoxide donor (PCOD585), exhibiting a notable neuroprotective outcome on the rat middle cerebral artery occlusion model and rendering an exciting intervention opportunity toward ischemia-induced brain injuries. However, its therapeutic mechanism still needs to be addressed. In the pharmacological study, we found PCOD585 inhibited neuronal Bcl2/Bax/caspase-3 apoptosis pathway in the peri-infarcted area of stroke by scavenging ONOO-. ONOO- scavenging further led to decreased Acyl-CoA synthetase long-chain family member 4 and increased glutathione peroxidase 4, to minimize lipoperoxidation. Additionally, the carbon monoxide release upon the ONOO- reaction with PCOD585 further inhibited the neuronal Iron-dependent ferroptosis associated with ischemia-reperfusion. Such a synergistic neuroprotective mechanism of PCOD585 yields as potent a neuroprotective effect as Edaravone. Additionally, PCOD585 penetrates the blood-brain barrier and reduces the degradation of zonula occludens-1 by inhibiting matrix metalloproteinase-9, thereby protecting the integrity of the blood-brain barrier. Our study provides a new perspective for developing multi-functional compounds to treat ischemic stroke. </div> <a href="javascript:ShowArticleAbstract(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anti-lipid+peroxidation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anti-lipid peroxidation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ferroptosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ferroptosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Iron+homeostasis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Iron homeostasis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ischemic%2freperfusion+injury%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ischemic/reperfusion injury</a></li></ul> <a href="javascript:ShowArticleKeywords(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Peroxynitrous+Acid%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Peroxynitrous Acid/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ischemic+Stroke%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ischemic Stroke/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ischemic+Stroke%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ischemic Stroke/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ischemic+Stroke%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ischemic Stroke/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Apoptosis%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Apoptosis/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ferroptosis%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ferroptosis/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neurons%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neurons/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neurons%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neurons/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neurons%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neurons/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+Monoxide%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon Monoxide/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+Monoxide%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon Monoxide/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuroprotective+Agents%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuroprotective Agents/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuroprotective+Agents%2ftherapeutic+use%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuroprotective Agents/therapeutic use</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Blood-Brain+Barrier%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Blood-Brain Barrier/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Blood-Brain+Barrier%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Blood-Brain Barrier/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Blood-Brain+Barrier%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Blood-Brain Barrier/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Treatment+Outcome%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Treatment Outcome</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Infarction%2c+Middle+Cerebral+Artery%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Infarction, Middle Cerebral Artery/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Infarction%2c+Middle+Cerebral+Artery%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Infarction, Middle Cerebral Artery/drug therapy</a></li></ul> <a href="javascript:ShowArticleMeSH(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Natural+Science+Foundation+of+Jiangsu+Province%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">No. BK20211348 Natural Science Foundation of Jiangsu Province</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Xuzhou+Basic+Research+Program%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">KC21030 Xuzhou Basic Research Program</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Leadership+program+through+open+competition+in+Xuzhou+Medical+University%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">JBGS202203 Leadership program through open competition in Xuzhou Medical University</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postgraduate+Research+%26+Practice+Innovation+Program+of+Jiangsu+Province%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">No. KYCX21_2722 Postgraduate Research & Practice Innovation Program of Jiangsu Province</a></li></ul> <a href="javascript:ShowArticleGrant(5);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow6"> <td style="min-width: 40px; text-align: center;"> 6 </td> <td> <div id="citation6" class="article-citation"> <b>Lin P</b>, Tian Y, Borsdorff T, Li Z, Landgraf J, Wu H, Xue J, Ding D, Ye H, Zhu Y, Liu C. TROPOMI unravels transboundary transport pathways of atmospheric <span class="highlight-field">carbon monoxide</span> in Tibetan Plateau. <em>THE SCIENCE OF THE TOTAL ENVIRONMENT</em> 2024;<b>952</b>:175942. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39218113' target='_blank'>39218113</a> DOI: <a href='https://dx.doi.org/10.1016/j.scitotenv.2024.175942' target='_blank'>10.1016/j.scitotenv.2024.175942</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.scitotenv.2024.175942','39218113', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(6);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(6);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.scitotenv.2024.175942' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 03/08/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/04/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv6" value="10.1016/j.scitotenv.2024.175942" /> <div style="display: none" id="articleAbstract6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Numerous studies have reported in situ monitoring and source analysis in the Tibetan Plateau (TP), a region crucial for climate systems. However, a gap remains in understanding the comprehensive distribution of atmospheric pollutants in the TP and their transboundary pollution transport. Here, we analyzed the high-resolution satellite TROPOMI observations from 2018 to 2023 in Tibet and its surrounding areas. Our result reveals that, contrary to the results from in situ surface CO monitoring, Tibet exhibits a distinct seasonality in atmospheric carbon monoxide total column average mixing ratio (XCO), with higher levels in summer and lower levels in winter. This distinctive seasonal pattern may be related to the TP's 'air pump' effect and the Asia summer monsoon. Before 2022, the annual growth rate of XCO in Tibet was 1.63 %·year-1; however, it declined by 6.88 % in 2022. Source analysis and satellite observations suggest that CO from South Asia may enter Tibet either by crossing the Himalayas or through the Yarlung Zangbo Grand Canyon. We discovered that spring outbreaks of open biomass burning (OBB) in South and Southeast Asia led to an 11.57-27.98 % increase in XCO over Tibet. Favorable wind pattern and unique topography of the canyon promote the high concentrations CO transport to Tibet. Our greater concern is whether the TP will experience more severe transboundary pollution in the future. </div> <a href="javascript:ShowArticleAbstract(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Open+biomass+burning%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Open biomass burning</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Satellite+remote+sensing%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Satellite remote sensing</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Transboundary+transport%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Transboundary transport</a></li></ul> <a href="javascript:ShowArticleKeywords(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(6);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow7"> <td style="min-width: 40px; text-align: center;"> 7 </td> <td> <div id="citation7" class="article-citation"> <b>Marcos-Rodrigo E</b>, Lebrero R, Muñoz R, Sousa DZ, Cantera S. Syngas biological transformation into hydroxyectoine. <em>BIORESOURCE TECHNOLOGY</em> 2024;<b>417</b>:131842. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39566695' target='_blank'>39566695</a> DOI: <a href='https://dx.doi.org/10.1016/j.biortech.2024.131842' target='_blank'>10.1016/j.biortech.2024.131842</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.biortech.2024.131842','39566695', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(7);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(7);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.biortech.2024.131842' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 09/04/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 11/11/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 11/16/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/22/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv7" value="10.1016/j.biortech.2024.131842" /> <div style="display: none" id="articleAbstract7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Syngas from the gasification of organic wastes represents a promising feedstock for fostering a sustainable bioeconomy. However, its potential is currently constrained by the low-value products generated. Osmolytes, such as hydroxyectoine, are high-value compounds, however, their biological production as isolated osmolytes is not yet cost-effective. This study utilized shotgun genomics and laboratory validation to find a carboxydotrophic, halotolerant bacterium, Hydrogenibacillus schlegelii, that could produce hydroxyectoine using H2, CO and CO2 as the sole source of energy and carbon. Subsequently, NaCl concentration, temperature and syngas composition were optimized in semi-continuous bioreactors. Optimal conversion of CO into hydroxyectoine occurred at a gas composition of 70 %:10 % CO:H2 (v/v) (44.8 ± 10.1 mghydroxyectoine·gbiomass-1). NaCl concentrations of 5 % significantly enhanced hydroxyectoine content (46.7 ± 9.5 mghydroxyectoine·gbiomass-1), but negatively affected gas consumption. This study opens new perspectives for the valorisation of syngas into hydroxyectoine, and for new cell platforms for pharmaceutical production based on syngas. </div> <a href="javascript:ShowArticleAbstract(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Extremophiles%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Extremophiles</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gas+fermentation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gas fermentation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrogenibacillus+schlegelii%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrogenibacillus schlegelii</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Osmolytes%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Osmolytes</a></li></ul> <a href="javascript:ShowArticleKeywords(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(7);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow8"> <td style="min-width: 40px; text-align: center;"> 8 </td> <td> <div id="citation8" class="article-citation"> <b>Elghandour MMMY</b>, Pacheco EBF, Dada OA, De Palo P, Maggiolino A, Salem AZM. The potential Impact of bacterial probiotics on ruminal greenhouse gases production in vitro of dietary Delonix regia seeds in rams and steers. <em>ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH INTERNATIONAL</em> 2024:10.1007/s11356-024-35504-y. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39560865' target='_blank'>39560865</a> DOI: <a href='https://dx.doi.org/10.1007/s11356-024-35504-y' target='_blank'>10.1007/s11356-024-35504-y</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/s11356-024-35504-y','39560865', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(8);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(8);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1007/s11356-024-35504-y' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/09/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/20/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv8" value="10.1007/s11356-024-35504-y" /> <div style="display: none" id="articleAbstract8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">This study aimed to evaluate the influence of probiotic bacteria (Pediococcus acidilactici BX-B122 and Bacillus coagulans BX-B118) on methane, carbon monoxide, and hydrogen sulfide, and fermentation profile of dietary Delonix regia seeds in ruminant. Ruminal contents from slaughtered rams and steers were used as inoculum for in vitro fermentation system. The total gas, methane, carbon monoxide, and hydrogen sulfide volume, as well as pH and dry matter degradability, were quantified in three fermentation cycles. Probiotic bacteria reduced the production of methane and hydrogen sulfide, while also increasing (P < 0.05) dry matter biodegradability, short-chain fatty acids, and metabolizable energy in both rams and steers. Delonix regia seeds at 6, 12, and 18% reduced total gas production. Higher production of methane and carbon monoxide was observed in rams compared to steers. Interestingly, no impact (P > 0.05) on the pH of the ruminal contents was found in Delonix regia seeds alone or in combination with probiotics. However, higher (P < 0.05) methane conversion efficiency (i.e., ratios of methane: short-chain fatty acids, methane: metabolizable energy, and methane: organic matter) was observed in experimental diets with Delonix regia seeds compared to diets containing both Delonix regia seeds and probiotic bacteria. In conclusion, dietary inclusion of 6, 12, and 18% of Delonix regia seeds with probiotic bacteria (Pediococcus acidilactici BX-B122 and Bacillus coagulans BX-B118) can mitigate the production of methane and hydrogen sulfide, while also increasing dry matter biodegradability, short-chain fatty acids, and metabolizable energy both ruminant animals. </div> <a href="javascript:ShowArticleAbstract(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22%5cn+++++++++++++++++++++Bacillus+coagulans%5cn++++++++++++++++++%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank"> Bacillus coagulans </a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22%5cn+++++++++++++++++++++Delonix+regia%5cn++++++++++++++++++%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank"> Delonix regia </a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22%5cn+++++++++++++++++++++Pediococcus+acidilactici%5cn++++++++++++++++++%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank"> Pediococcus acidilactici </a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Methane%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Methane</a></li></ul> <a href="javascript:ShowArticleKeywords(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(8);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow9"> <td style="min-width: 40px; text-align: center;"> 9 </td> <td> <div id="citation9" class="article-citation"> <b>Ramel-Delobel M</b>, Heydari S, de Nazelle A, Praud D, Salizzoni P, Fervers B, Coudon T. Air pollution exposure in active versus passive travel modes across five continents: A Bayesian random-effects meta-analysis. <em>ENVIRONMENTAL RESEARCH</em> 2024;<b>261</b>:119666. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39074774' target='_blank'>39074774</a> DOI: <a href='https://dx.doi.org/10.1016/j.envres.2024.119666' target='_blank'>10.1016/j.envres.2024.119666</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.envres.2024.119666','39074774', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(9);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(9);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(9);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.envres.2024.119666' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/12/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 07/21/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 07/31/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv9" value="10.1016/j.envres.2024.119666" /> <div style="display: none" id="articleAbstract9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Epidemiological studies on health effects of air pollution usually estimate exposure at the residential address. However, ignoring daily mobility patterns may lead to biased exposure estimates, as documented in previous exposure studies. To improve the reliable integration of exposure related to mobility patterns into epidemiological studies, we conducted a systematic review of studies across all continents that measured air pollution concentrations in various modes of transport using portable sensors. To compare personal exposure across different transport modes, specifically active versus motorized modes, we estimated pairwise exposure ratios using a Bayesian random-effects meta-analysis. Overall, we included measurements of six air pollutants (black carbon (BC), carbon monoxide (CO), nitrogen dioxide (NO2), particulate matter (PM10, PM2.5) and ultrafine particles (UFP)) for seven modes of transport (i.e., walking, cycling, bus, car, motorcycle, overground, underground) from 52 published studies. Compared to active modes, users of motorized modes were consistently the most exposed to gaseous pollutants (CO and NO2). Cycling and walking were the most exposed to UFP compared to other modes. Active vs passive mode contrasts were mostly inconsistent for other particle metrics. Compared to active modes, bus users were consistently more exposed to PM10 and PM2.5, while car users, on average, were less exposed than pedestrians. Rail modes experienced both some lower exposures (compared to cyclists for PM10 and pedestrians for UFP) and higher exposures (compared to cyclist for PM2.5 and BC). Ratios calculated for motorcycles should be considered carefully due to the small number of studies, mostly conducted in Asia. Computing exposure ratios overcomes the heterogeneity in pollutant levels that may exist between continents and countries. However, formulating ratios on a global scale remains challenging owing to the disparities in available data between countries. </div> <a href="javascript:ShowArticleAbstract(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Active+modes%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Active modes</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Black+carbon%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Black carbon</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nitrogen+dioxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nitrogen dioxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Particulate+matter%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Particulate matter</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ultrafine+particles%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ultrafine particles</a></li></ul> <a href="javascript:ShowArticleKeywords(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bayes+Theorem%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bayes Theorem</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Air+Pollution%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Air Pollution/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Air+Pollution%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Air Pollution/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Air+Pollutants%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Air Pollutants/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Environmental+Exposure%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Environmental Exposure/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Particulate+Matter%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Particulate Matter/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+Monoxide%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon Monoxide/analysis</a></li></ul> <a href="javascript:ShowArticleMeSH(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(9);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow10"> <td style="min-width: 40px; text-align: center;"> 10 </td> <td> <div id="citation10" class="article-citation"> <b>Zhu C</b>, Yu M, Lv J, Sun F, Qin A, Chen Z, Hu X, Yang Z, Fang Z. De novo strategy of organic semiconducting polymer brushes for NIR-II light-triggered <span class="highlight-field">carbon monoxide</span> release to boost deep-tissue cancer phototheranostics. <em class='incite-journal-name' onclick='ShowInCiteJournal(14587);'>J Nanobiotechnology</em> 2024;<b>22</b>:708. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39543646' target='_blank'>39543646</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11562092' target='_blank'>PMC11562092</a> DOI: <a href='https://dx.doi.org/10.1186/s12951-024-02984-6' target='_blank'>10.1186/s12951-024-02984-6</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1186/s12951-024-02984-6','39543646', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(10);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(10);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(10);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(10);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1186/s12951-024-02984-6' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(14587);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/07/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 11/04/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/17/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv10" value="10.1186/s12951-024-02984-6" /> <div style="display: none" id="articleAbstract10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">The integration of photoacoustic imaging (PAI) and photothermal therapy (PTT) within the second near-infrared (NIR-II) window, offering a combination of high-resolution imaging and precise non-invasive thermal ablation, presents an attractive opportunity for cancer treatment. Despite the significant promise, the development of this noninvasive phototheranostic nanomedicines encounters challenges that stem from tumor thermotolerance and limited therapeutic efficacy. In this contribution, we designed an amphiphilic semiconducting polymer brush (SPB) featuring a thermosensitive carbon monoxide (CO) donor (TDF-CO) for NIR-II PAI-assisted gas-augmented deep-tissue tumor PTT. TDF-CO nanoparticles (NPs) exhibited a powerful photothermal conversion efficiency (43.1%) and the capacity to trigger CO release after NIR-II photoirradiation. Notably, the liberated CO not only acts on mitochondria, leading to mitochondrial dysfunction and promoting cellular apoptosis but also hinders the overexpression of heat shock proteins (HSPs), enhancing the tumor's thermosensitivity to PTT. This dual action accelerates cellular thermal ablation, achieving a gas-augmented synergistic therapeutic effect in cancer treatment. Intravenous administration of TDF-CO NPs in 4T1 tumor-bearing mice demonstrated bright PAI signals and remarkable tumor ablation under 1064 nm laser irradiation, underscoring the potential of CO-mediated photothermal/gas synergistic therapy. We envision this tailor-made multifunctional NIR-II light-triggered SPB provides a feasible approach to amplify the performance of PTT for advancing future cancer phototheranostics. </div> <a href="javascript:ShowArticleAbstract(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Organic+semiconducting+polymer+brushes%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Organic semiconducting polymer brushes</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Photoacoustic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Photoacoustic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Photothermal+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Photothermal therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Second+near-infrared+window%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Second near-infrared window</a></li></ul> <a href="javascript:ShowArticleKeywords(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+Monoxide%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon Monoxide/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Polymers%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Polymers/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Theranostic+Nanomedicine%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Theranostic Nanomedicine/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Infrared+Rays%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Infrared Rays</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Line%2c+Tumor%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Line, Tumor</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Photothermal+Therapy%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Photothermal Therapy/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Photoacoustic+Techniques%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Photoacoustic Techniques/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%2c+Inbred+BALB+C%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice, Inbred BALB C</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Semiconductors%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Semiconductors</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nanoparticles%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nanoparticles/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Phototherapy%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Phototherapy/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neoplasms%2ftherapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neoplasms/therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neoplasms%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neoplasms/drug therapy</a></li></ul> <a href="javascript:ShowArticleMeSH(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Joint+Funds+for+the+innovation+of+science+and+Technology%2c+Fujian+province%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">2023Y9320 Joint Funds for the innovation of science and Technology, Fujian province</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Joint+Funds+for+the+innovation+of+science+and+Technology%2c+Fujian+province%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">2023Y9320 Joint Funds for the innovation of science and Technology, Fujian province</a></li></ul> <a href="javascript:ShowArticleGrant(10);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow11"> <td style="min-width: 40px; text-align: center;"> 11 </td> <td> <div id="citation11" class="article-citation"> <b>Ren H</b>, Bai Y, Liu Z, Ma C, Tao X, Wang Q, Lian H, Li X. A multifunctional cascade gas-nanoreactor with MnO<sub>2</sub> as a gatekeeper to enhance starvation therapy and provoke antitumor immune response. <em class='incite-journal-name' onclick='ShowInCiteJournal(337);'>Acta Biomater</em> 2024:S1742-7061(24)00658-5. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39521315' target='_blank'>39521315</a> DOI: <a href='https://dx.doi.org/10.1016/j.actbio.2024.11.004' target='_blank'>10.1016/j.actbio.2024.11.004</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.actbio.2024.11.004','39521315', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(11);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(11);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.actbio.2024.11.004' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(337);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/16/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/11/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 11/06/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/16/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv11" value="10.1016/j.actbio.2024.11.004" /> <div style="display: none" id="articleAbstract11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Glucose oxidase (GOx)-mediated starvation therapy is an effective tumor treatment that blocks energy and activates the immune response. However, the insufficient tumor immunogenicity and immunosuppressive tumor microenvironment (TME) limited its therapeutic efficacy. To address this, we have designed a multifunctional cascade gas-nanoreactor with a MnO2 coating, which serves as an out gatekeeper to encapsulate both GOx and a carbon monoxide (CO) donor (denoted as GCM). Due to the protective effect of MnO2 coating, GCM maintains better stability in normal physiological environments, enhancing the catalytic activity of GOx and minimizing toxic side effects. Upon accumulation in the tumor, the degradation of MnO2 coating exposes the GOx enzyme, thereby initiating a cascade catalysis reaction to generate hydrogen peroxide (H2O2) and release CO in the hypoxic conditions. Additionally, the released Mn2+ reacts with H2O2 to generate toxic hydroxyl radical (•OH) as chemodynamic therapy (CDT). The synergistic treatments of starvation therapy, CO gas therapy and CDT effectively kill cancer cells and amplify immunogenic cell death (ICD), maturing DC cells and activating anti-tumor immune response. Furthermore, the released CO increases M1 macrophages infiltration and reduces myeloid-derived suppressor cells (MDSCs) infiltration, thus reversing the immunosuppressive TME. This multifunctional gas-nanoreactor provides a strategy for CO gas generation to trigger a robust anti-tumor immune response and has the potential for clinical application in cancer immunotherapy. STATEMENT OF SIGNIFICANCE: A multifunctional cascade gas-nanoreactor with a MnO2 gatekeeper was developed to perform synergistic treatments involving starvation therapy, CO gas therapy and chemodynamic therapy (CDT) for tumor elimination. The MnO2 gatekeeper enhanced the catalytic activity of GOx within the nanoreactor by generating oxygen, thereby minimizing toxic side effects after intravenous injection. The gas-nanoreactor amplified ICD through synergistic treatments to mature DC cells and activate anti-tumor immune response. Furthermore, the released CO could reverse the immunosuppression of the TME to enhance cancer immunotherapy. The combination strategy utilizing the gas-nanoreactor demonstrates clinical potential for facilitating cancer immunotherapy. </div> <a href="javascript:ShowArticleAbstract(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anti-tumor+immune+response%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anti-tumor immune response</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cascade+Gas-nanoreactor%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cascade Gas-nanoreactor</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Glucose+oxidase%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Glucose oxidase</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Synergistic+treatments%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Synergistic treatments</a></li></ul> <a href="javascript:ShowArticleKeywords(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(11);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow12"> <td style="min-width: 40px; text-align: center;"> 12 </td> <td> <div id="citation12" class="article-citation"> <b>Pan C</b>, Zuo C, Chen J, Zhang Q, Deng L, Liu Y, Ding P. Constructing sodium alginate/carboxymethyl chitosan coating capable of catalytically releasing NO or CO for improving the hemocompatibility and endothelialization of magnesium alloys. <em class='incite-journal-name' onclick='ShowInCiteJournal(11467);'>Int J Biol Macromol</em> 2024;<b>279</b>:135166. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39214216' target='_blank'>39214216</a> DOI: <a href='https://dx.doi.org/10.1016/j.ijbiomac.2024.135166' target='_blank'>10.1016/j.ijbiomac.2024.135166</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.ijbiomac.2024.135166','39214216', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(12);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(12);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(12);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.ijbiomac.2024.135166' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(11467);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/16/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/12/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/27/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/04/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv12" value="10.1016/j.ijbiomac.2024.135166" /> <div style="display: none" id="articleAbstract12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Although significant progress in developing biodegradable magnesium alloy materials in cardiovascular stents has been achieved recently, they still face challenges such as rapid in vivo corrosion degradation, inferior blood compatibility, and limited re-endothelialization after the implantation. Hydrogel coating that can catalyze the liberation of gas signal molecules offers a good solution to alleviate the corrosion rate and enhance the biocompatibility of magnesium and its alloys. In this study, based on alkaline heat treatment and construction of polydopamine coating on the surface of magnesium alloy, sodium alginate/carboxymethyl chitosan (SA/CMCS) gel was simultaneously covalently grafted onto the surface to build a natural polymer hydrogel coating, and selenocystamine (SeCA) and CO release molecules (CORM-401) were respectively immobilized on the surface of the hydrogel coating to ameliorate the anticoagulant performance and accelerate endothelial cells (ECs) growth by catalyzing the release of endogenous gas signal molecules (NO or CO). The findings verified that the as-prepared hydrogel coating can catalyze the liberation of CO or NO and significantly improve the corrosion resistance of magnesium alloy. At the same time, owing to the excellent hydrophilicity of the hydrogel coating, the good anticoagulant property of sodium alginate, and the ability of CMCS to promote the ECs growth, the modified magnesium alloy could significantly improve the albumin adsorption while preventing the adsorption of fibrinogen, hence significantly augmenting the anticoagulant properties and promoting the ECs growth. Under the catalytic release of NO or CO, the released gas molecules further enhanced hemocompatibility and promoted endothelial cell (EC) growth and the expression of vascular endothelial growth factor (VEGF) and NO of ECs. Therefore, the bioactive coatings that can catalyze the release of NO or CO have potential applications in constructing surface bioactive coatings for magnesium alloy materials used for intravascular stents. </div> <a href="javascript:ShowArticleAbstract(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Endothelial+cell%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Endothelial cell</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hemocompatibility%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hemocompatibility</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Magnesium+alloy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Magnesium alloy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nitric+oxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nitric oxide</a></li></ul> <a href="javascript:ShowArticleKeywords(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chitosan%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chitosan/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chitosan%2fanalogs+%26amp%3b+derivatives%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chitosan/analogs & derivatives</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chitosan%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chitosan/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Alginates%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Alginates/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Alginates%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Alginates/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Alloys%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Alloys/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Alloys%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Alloys/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Magnesium%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Magnesium/chemistry</a></li><li><a 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href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrogels%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrogels/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrogels%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrogels/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Endothelial+Cells%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Endothelial Cells/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Endothelial+Cells%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Endothelial Cells/metabolism</a></li></ul> <a href="javascript:ShowArticleMeSH(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(12);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow13"> <td style="min-width: 40px; text-align: center;"> 13 </td> <td> <div id="citation13" class="article-citation"> <b>Hwang H</b>, Lee S, Kim KM, Cha YS. <span class="highlight-field">Carbon monoxide</span> poisoning is associated with an increased risk of epilepsy and status epilepticus: a nationwide population-based cohort study conducted in the Republic of Korea between 2002-2021. <em class='incite-journal-name' onclick='ShowInCiteJournal(6709);'>Clin Toxicol (Phila)</em> 2024:1-7. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39466339' target='_blank'>39466339</a> DOI: <a href='https://dx.doi.org/10.1080/15563650.2024.2418138' target='_blank'>10.1080/15563650.2024.2418138</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1080/15563650.2024.2418138','39466339', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(13);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(13);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1080/15563650.2024.2418138' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(6709);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 03/13/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/10/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/11/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/30/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv13" value="10.1080/15563650.2024.2418138" /> <div style="display: none" id="articleAbstract13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">INTRODUCTION</div><div class="abstract-content">Carbon monoxide poisoning may result in various neurological injuries, including acute symptomatic seizures. We aimed to investigate the long-term risk of epilepsy and status epilepticus in patients with previous carbon monoxide poisoning. </div><div class="abstract-label">METHODS</div><div class="abstract-content">The study population was derived from the National Health Insurance Service database of the Republic of Korea between 1 January 2002 and 31 December 2021. We included adults with at least one documented visit to medical facilities because of carbon monoxide poisoning (International Classification of Diseases, Tenth Revision, code T58). Patients were matched, on the same index date, with controls, without a T58 code, for age, sex, insurance type, income level, and residence location in a 1:1 ratio. Follow-up continued until death, migration, or the end of the observation period (31 December 2021). The primary outcome was the incidence of epilepsy (codes G40 or R56) and status epilepticus (code G41). </div><div class="abstract-label">RESULTS</div><div class="abstract-content">This study included 53,380 patients with carbon monoxide poisoning and 53,380 controls, with 44.2% women and a mean age of 45.7 years. The mean (±SD) follow-up period was 5.7 ± 4.3 years in the carbon monoxide poisoned group and 6.4 ± 4.4 years in controls. The overall risk of epilepsy (adjusted hazard ratio 2.60; 95% CI: 2.43-2.78; P < 0.001) and status epilepticus (adjusted hazard ratio 4.10; 95% CI: 2.84-5.92; P < 0.001) was significantly increased in the carbon monoxide poisoned group compared to controls. The risk of epilepsy and status epilepticus was increased in patients with previous carbon monoxide poisoning, regardless of sex, age or a history of stroke, neurodegenerative diseases, or central nervous system tumour or infection. However, in the subgroup analysis according to age, the highest risk of epilepsy and status epilepticus was observed in patients less than 40 years of age. </div><div class="abstract-label">DISCUSSION</div><div class="abstract-content">In this population-based cohort study, previous carbon monoxide poisoning was associated with an increased risk of epilepsy and status epilepticus. The risk was more noticeable in patients aged less than 40 years. Further studies are needed to confirm such an association in other populations. </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">Previous carbon monoxide poisoning was associated with an increased risk of epilepsy and status epilepticus, particularly in the younger population. The long-term management of survivors of carbon monoxide poisoning should include monitoring for epilepsy and status epilepticus. </div> <a href="javascript:ShowArticleAbstract(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22carbon+monoxide+poisoning%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">carbon monoxide poisoning</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22epilepsy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">epilepsy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22seizures%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">seizures</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22status+epilepticus%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">status epilepticus</a></li></ul> <a href="javascript:ShowArticleKeywords(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(13);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow14"> <td style="min-width: 40px; text-align: center;"> 14 </td> <td> <div id="citation14" class="article-citation"> <b>Rolnik A</b>, Olas B, Szablińska-Piernik J, Lahuta LB, Gromadziński L, Majewski MS. Antioxidant and anticoagulant properties of myo-inositol determined in an ex vivo studies and gas chromatography analysis. <em class='incite-journal-name' onclick='ShowInCiteJournal(20954);'>Sci Rep</em> 2024;<b>14</b>:25633. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39465311' target='_blank'>39465311</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11514185' target='_blank'>PMC11514185</a> DOI: <a href='https://dx.doi.org/10.1038/s41598-024-76527-2' target='_blank'>10.1038/s41598-024-76527-2</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1038/s41598-024-76527-2','39465311', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(14);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(14);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(14);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(14);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1038/s41598-024-76527-2' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(20954);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/11/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/15/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/29/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv14" value="10.1038/s41598-024-76527-2" /> <div style="display: none" id="articleAbstract14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Myo-inositol plays a key role in the vasculature and may be beneficial for preventing harmful environmental effects. In this study aortic rings were isolated from middle-aged (12-month-old) male Wistar rats and preincubated with myo-inositol (0.01-100 mg/L) for 2 h. A stable thromboxane A2 analog was added (0.1 nM, 2 h) to analyze vascular dysfunction. The concentration of myo-inositol in the organ baths was determined via gas chromatography. In another experiment, human blood plasma was subjected to pro-oxidant - hydrogen peroxide administration, and myo-inositol was added to analyze lipid and protein oxidation processes. The thromboplastin time, prothrombin time, and thrombin time were also studied. Myo-inositol administration protected thiol groups against oxidative stress, meanwhile decreased vascular contraction and potentiated vasodilation (concentrations 1-100 mg/L, but not ≤ 0.1 mg/L), and changed the level of 8-isoprostane (concentrations: 0.1-100 mg/L, but not 0.01 mg/L) in plasma treated with H2O2/Fe2+. A dose above 100 mg/L additionally protected lipids (measured as thiobarbituric acid reactive substances) and increased thrombin time. Moreover, significant differences in vascular relaxation were observed between the studied myo-inositol concentrations (1 vs. 10 vs. 100 mg/L), which was not detected under the 0.1 mg/L. The concentration of myo-inositol in the organ baths determined via gas chromatography revealed that this nutraceutical agent was not used by the aortic rings during the incubation period in physiological processes. A protective effect of myo-inositol against prooxidant damage to human plasma and rat thoracic arteries has been demonstrated. </div> <a href="javascript:ShowArticleAbstract(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Acetylcholine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Acetylcholine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Myo-inositol%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Myo-inositol</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reactive+oxygen+species%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reactive oxygen species</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Thromboxane+A2%5cn+++++++++++++++++++++%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Thromboxane A2 </a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22U-46619%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">U-46619</a></li></ul> <a href="javascript:ShowArticleKeywords(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Antioxidants%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Antioxidants/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Wistar%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Wistar</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inositol%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inositol/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inositol%2fanalogs+%26amp%3b+derivatives%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inositol/analogs & derivatives</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chromatography%2c+Gas%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chromatography, Gas</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Oxidative+Stress%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Oxidative Stress/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anticoagulants%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anticoagulants/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anticoagulants%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anticoagulants/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrogen+Peroxide%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrogen Peroxide/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aorta%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aorta/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aorta%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aorta/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Vasodilation%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Vasodilation/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Thrombin+Time%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Thrombin Time</a></li></ul> <a href="javascript:ShowArticleMeSH(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Statutory+fundings%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">61.610.007-110 Statutory fundings</a></li></ul> <a href="javascript:ShowArticleGrant(14);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow15"> <td style="min-width: 40px; text-align: center;"> 15 </td> <td> <div id="citation15" class="article-citation"> <b>Sharma A</b>, Srivastava S, Kumar R, Mitra D. Source attribution of <span class="highlight-field">carbon monoxide</span> over Northern India during crop residue burning period over Punjab. <em>ENVIRONMENTAL POLLUTION (BARKING, ESSEX : 1987)</em> 2024;<b>359</b>:124707. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39128605' target='_blank'>39128605</a> DOI: <a href='https://dx.doi.org/10.1016/j.envpol.2024.124707' target='_blank'>10.1016/j.envpol.2024.124707</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.envpol.2024.124707','39128605', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(15);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(15);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(15);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.envpol.2024.124707' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 12/31/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/05/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/07/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 08/13/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv15" value="10.1016/j.envpol.2024.124707" /> <div style="display: none" id="articleAbstract15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">National Capital Territory of Delhi and its satellite cities suffer from poor air quality during the post-monsoon months of October-November. In this study, a novel attempt is made to estimate the contribution of different emission sources (industrial, residential, power generation, transportation, biomass burning, photochemical production, lateral transport, etc.) towards the criteria air pollutant carbon monoxide (CO) concentration over North India. Multiple simulations of the WRF-Chem model with a tagged tracer approach with different inputs (6 anthropogenic emission inventories and 3 biomass burning emission inventories) were used. The model performance was evaluated against the MOPITT retrieved CO surface concentration. Analysis of model simulated CO over North India suggests that anthropogenic emissions contribute around 32-49% to surface CO concentration while crop residue burning contributes 27-44% of which 80% originates from Punjab. For Delhi, the contribution from anthropogenic sources is dominant (53-77%) of which 10-28% is from the domestic sector and 14-55% is from the transport sector. Agricultural waste burning contributes about 15-30% to Delhi's surface CO concentration (of which 75% originates from Punjab). Crop residue burning emission is a chief source of CO over Punjab with a contribution of about 56-76%. The results suggest that industrial, transport, and domestic sector activities are more responsible for increased CO levels over New Delhi and surrounding regions than crop residue burning over Punjab. Furthermore, critical meteorological parameters like 10 m wind speed, boundary layer height, 2 m temperature, total precipitation, and relative humidity were evaluated against CO concentration to understand their impact on CO distribution. Results conclude that deteriorating air quality over the North Indian region is caused by a combination of prevailing meteorological factors (such as slow winds, shallow mixing layer, and cold temperatures) and man-made emissions. </div> <a href="javascript:ShowArticleAbstract(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Crop+residue+burning%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Crop residue burning</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22New+Delhi%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">New Delhi</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Punjab%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Punjab</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22WRF-Chem%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">WRF-Chem</a></li></ul> <a href="javascript:ShowArticleKeywords(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22India%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">India</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+Monoxide%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon Monoxide/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Air+Pollutants%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Air Pollutants/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Environmental+Monitoring%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Environmental Monitoring</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Air+Pollution%2fstatistics+%26amp%3b+numerical+data%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Air Pollution/statistics & numerical data</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Crops%2c+Agricultural%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Crops, Agricultural</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Agriculture%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Agriculture</a></li></ul> <a href="javascript:ShowArticleMeSH(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(15);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow16"> <td style="min-width: 40px; text-align: center;"> 16 </td> <td> <div id="citation16" class="article-citation"> <b>Wang W</b>, Liu X, Xiao Y, Han S, Liu S, Wang B, Wang H. Real-time evolution characteristics and potential reactions of contaminants in commuter bus cabin air. <em>THE SCIENCE OF THE TOTAL ENVIRONMENT</em> 2024;<b>946</b>:174440. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38960182' target='_blank'>38960182</a> DOI: <a href='https://dx.doi.org/10.1016/j.scitotenv.2024.174440' target='_blank'>10.1016/j.scitotenv.2024.174440</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.scitotenv.2024.174440','38960182', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(16);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(16);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(16);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.scitotenv.2024.174440' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 01/24/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 06/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 06/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 07/05/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv16" value="10.1016/j.scitotenv.2024.174440" /> <div style="display: none" id="articleAbstract16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Despite the increasing use of motor vehicles, the impact of airborne pollutants and their health risks inside public transportation, such as commuter buses, is not well understood. This study assessed air quality inside an urban commuter bus by continuously monitoring PM10, PM2.5, and CO concentrations during both driving and parking periods. Our findings revealed that the ventilation system of the bus significantly reduced the infiltration of outdoor particulate matter and water vapor. However, CO concentrations were considerably higher inside the bus than outside, primarily due to vehicular self-emission. The ineffection of the ventilation system to remove CO potentially increases long-term exposure risks for passengers. The study identified ozone as a key oxidant in the cabin. Besides vehicle emissions, C3-C10 saturated aldehydes and carbonyl compounds were detected, including acetone, propanal, and hexanal. The presence of 6-MHO, an oxidation product of squalene, suggests that passengers contribute to VOCs load through direct emissions or skin surface reactions. Additionally, human respiration was found to significantly contribute to isoprene levels, estimated at 81.7 %. This research underscores the need for further investigation into the cumulative effects of stable compounds in cabin air and provides insights for developing healthier public transportation systems. </div> <a href="javascript:ShowArticleAbstract(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cabin+air%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cabin air</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Commuter+buses%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Commuter buses</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Organic+compounds%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Organic compounds</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Particulate+matter%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Particulate matter</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sources%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sources</a></li></ul> <a href="javascript:ShowArticleKeywords(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Air+Pollutants%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Air Pollutants/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Environmental+Monitoring%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Environmental Monitoring</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Vehicle+Emissions%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Vehicle Emissions/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Motor+Vehicles%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Motor Vehicles</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Particulate+Matter%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Particulate Matter/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Air+Pollution%2c+Indoor%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Air Pollution, Indoor/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li></ul> <a href="javascript:ShowArticleMeSH(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(16);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow17"> <td style="min-width: 40px; text-align: center;"> 17 </td> <td> <div id="citation17" class="article-citation"> <b>Silver J</b>, den Engelsen D, Al-Jaff G, Taies JA, Wilson MT, Fern GR. Protoporphyrin IX iron(II) revisited. An overview of the Mössbauer spectroscopic parameters of low-spin porphyrin iron(II) complexes. <em class='incite-journal-name' onclick='ShowInCiteJournal(13184);'>J Biol Inorg Chem</em> 2024:10.1007/s00775-024-02075-9. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39384634' target='_blank'>39384634</a> DOI: <a href='https://dx.doi.org/10.1007/s00775-024-02075-9' target='_blank'>10.1007/s00775-024-02075-9</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/s00775-024-02075-9','39384634', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(17);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(17);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(17);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1007/s00775-024-02075-9' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(13184);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/23/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/19/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/11/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv17" value="10.1007/s00775-024-02075-9" /> <div style="display: none" id="articleAbstract17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Mössbauer parameters of low-spin six-coordinate [Fe(II)(Por)L2] complexes (where Por is a synthetic porphyrin; L is a nitrogenous aliphatic, an aromatic base or a heterocyclic ligand, a P-bonding ligand, CO or CN) and low-spin [Fe(Por)LX] complexes (where L and X are different ligands) are reported. A known point charge calculation approach was extended to investigate how the axial ligands and the four porphyrinato-N atoms generate the observed quadrupole splittings (ΔEQ) for the complexes. Partial quadrupole splitting (p.q.s.) and partial chemical shifts (p.c.s.) values were derived for all the axial ligands, and porphyrins reported in the literature. The values for each porphyrin are different emphasising the importance/uniqueness of the [Fe(PPIX)] moiety, (which is ubiquitous in nature). This new analysis enabled the construction of figures relating p.c.s and p.q.s values. The relationships presented in the figures indicates that strong field ligands such as CO can, and do change the sign of the electric field gradient in the [Fe(II)(Por)L2] complexes. The limiting p.q.s. value a ligand can have and still form a six-coordinate low-spin [Fe(II)(Por)L2] complex is established. It is shown that the control the porphyrin ligands exert on the low-spin Fe(II) atom limits its bonding to a defined range of axial ligands; outside this range the spin state of the iron is unstable and five-coordinate high-spin complexes are favoured. Amongst many conclusions, it was found that oxygen cannot form a stable low-spin [Fe(II)(Por)L(O2)] complex and that oxy-haemoglobin is best described as an [Fe(III)(Por)L(O2-)] complex, the iron is ferric bound to the superoxide molecule. </div> <a href="javascript:ShowArticleAbstract(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Haemoglobin%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Haemoglobin</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Iron+porphyrins%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Iron porphyrins</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Myoglobin%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Myoglobin</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22M%c3%b6ssbauer+spectroscopy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mössbauer spectroscopy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nitrogenous+bases%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nitrogenous bases</a></li></ul> <a href="javascript:ShowArticleKeywords(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Innovate+UK%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">10110040 Innovate UK</a></li></ul> <a href="javascript:ShowArticleGrant(17);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow18"> <td style="min-width: 40px; text-align: center;"> 18 </td> <td> <div id="citation18" class="article-citation"> <b>Bai J</b>, Sun WB, Zheng WC, Wang XP, Bai Y. <span class="highlight-field">Carbon monoxide</span>-releasing molecule-3 ameliorates traumatic brain injury-induced cardiac dysfunctions via inhibition of pyroptosis and apoptosis. <em class='incite-journal-name' onclick='ShowInCiteJournal(17379);'>Mol Cell Biochem</em> 2024:10.1007/s11010-024-05130-w. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39377871' target='_blank'>39377871</a> DOI: <a href='https://dx.doi.org/10.1007/s11010-024-05130-w' target='_blank'>10.1007/s11010-024-05130-w</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/s11010-024-05130-w','39377871', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(18);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(18);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(18);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1007/s11010-024-05130-w' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(17379);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/16/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/09/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv18" value="10.1007/s11010-024-05130-w" /> <div style="display: none" id="articleAbstract18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Traumatic brain injury (TBI) frequently results in cardiac dysfunction and impacts the quality of survivors' life. It has been reported that carbon monoxide-releasing molecule-3 (CORM-3) administration immediately after hemorrhagic shock and resuscitation (HSR) ameliorated the HSR‑induced cardiac dysfunctions. The purpose of this study was to determine whether the application of CORM-3 on TBI exerted therapeutic effects against TBI-induced cardiac dysfunctions. Rats were randomly divided into four groups (n = 12) including Sham, TBI, TBI/CORM-3 and TBI/inactive CORM-3 (iCORM-3) groups. TBI was established by a weight-drop model. The rats in the TBI/CORM-3 group and TBI/iCORM-3 group were intravenously injected with CORM-3 and iCORM-3 (4 mg/kg) following TBI, respectively. The time of death in the rats that did not survive within 24 h was recorded. 24 h post-trauma, the cardiac function, pathological change, serum troponin T and creatine kinase-MB (CK-MB) levels, pyroptosis, apoptosis and expressions of TUNEL staining, Gasdermin D (GSDMD), IL-1β, IL-18, ratio Bax/Bcl-2 were assessed by echocardiography, hematoxylin-eosin staining, chemiluminescence, immunofluorescence, and western blot assays, respectively. TBI-treated rats exhibited dramatically decreased ejection fraction and aggravated myocardial injury, increased mortality rate, elevated levels of serum troponin T and CK-MB, promoted cardiac pyroptosis and apoptosis, and upregulated expressions of cleaved caspase-3, GSDMD N-terminal fragments, IL-1β, IL-18, and ratio of Bax/Bcl-2, whereas CORM-3 partially reversed these changes. CORM-3 ameliorated TBI-induced cardiac injury and dysfunction. This mechanism may be responsible for the inhibition of pyroptosis and apoptosis in cardiomyocyte. </div> <a href="javascript:ShowArticleAbstract(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Apoptosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Apoptosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cardiac+dysfunction%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cardiac dysfunction</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pyroptosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pyroptosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Traumatic+brain+injury%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Traumatic brain injury</a></li></ul> <a href="javascript:ShowArticleKeywords(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Department+of+Health+of+Hebei+Province%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">20240666 Department of Health of Hebei Province</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Department+of+Health+of+Hebei+Province%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">20240666 Department of Health of Hebei Province</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Department+of+Health+of+Hebei+Province%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">20240666 Department of Health of Hebei Province</a></li></ul> <a href="javascript:ShowArticleGrant(18);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow19"> <td style="min-width: 40px; text-align: center;"> 19 </td> <td> <div id="citation19" class="article-citation"> <b>Wang Q</b>, Li A, Li Q, Li J, Wang Q, Wu S, Meng J, Liu C, Wang D, Chen Y. <span class="highlight-field">Carbon monoxide</span> attenuates cellular senescence-mediated pulmonary fibrosis via modulating p53/PAI-1 pathway. <em class='incite-journal-name' onclick='ShowInCiteJournal(8802);'>Eur J Pharmacol</em> 2024;<b>980</b>:176843. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39068977' target='_blank'>39068977</a> DOI: <a href='https://dx.doi.org/10.1016/j.ejphar.2024.176843' target='_blank'>10.1016/j.ejphar.2024.176843</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.ejphar.2024.176843','39068977', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(19);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(19);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(19);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.ejphar.2024.176843' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(8802);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 01/22/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/10/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 07/22/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 07/30/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv19" value="10.1016/j.ejphar.2024.176843" /> <div style="display: none" id="articleAbstract19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">PURPOSE</div><div class="abstract-content">Idiopathic pulmonary fibrosis (IPF) is a fatal progressive condition often requiring lung transplantation. Accelerated senescence of type II alveolar epithelial cells (AECII) plays a crucial role in pulmonary fibrosis progression through the secretion of the senescence-associated secretory phenotype (SASP). Low-dose carbon monoxide (CO) possesses anti-inflammatory, anti-oxidative, and anti-aging properties. This study aims to explore the preventive effects of CO-releasing molecule 2 (CORM2) in a bleomycin-induced pulmonary fibrosis model. </div><div class="abstract-label">METHODS</div><div class="abstract-content">We established an pulmonary fibrosis model in C57BL/6J mice and evaluated the impact of CORM2 on fibrosis pathology using Masson's trichrome staining, fluorescence staining, and pulmonary function tests. Fibrogenic marker expression and SASP secretion in tissues and AECII cells were analyzed using qRT-PCR, Western blot, and ELISA assays both in vivo and in vitro. Additionally, we investigated DNA damage and cellular senescence through immunofluorescence and SA-β-gal staining. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">CORM2 showed a preventive effect on bleomycin-induced lung fibrosis by improving pulmonary function and reducing the expression of fibrosis-related genes, such as TGF-β, α-SMA, Collagen I/III. CORM2 decreased the DNA damage response by inhibiting γ-H2AX, p53, and p21. We identified PAI-1 as a new target gene that was downregulated by CORM2, and which was associated with cellular senescence and fibrosis. CORM2 effectively inhibited cellular senescence and delayed EMT occurrence in AECII cells. </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">Our study highlights the potential of CORM2 in preventing DNA damage-induced cellular senescence in bleomycin-induced pulmonary fibrosis through modulation of the p53/PAI-1 signaling pathway. These findings underscore the promising prospects of CORM2 in targeting cellular senescence and the p53/PAI-1 pathway as a potential preventive strategy for IPF. </div> <a href="javascript:ShowArticleAbstract(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cellular+senescence%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cellular senescence</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22DNA+damage+response%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">DNA damage response</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Plasminogen+activator+inhibitor+1%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Plasminogen activator inhibitor 1</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pulmonary+fibrosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pulmonary fibrosis</a></li></ul> <a href="javascript:ShowArticleKeywords(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bleomycin%2ftoxicity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bleomycin/toxicity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+Monoxide%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon Monoxide/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+Monoxide%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon Monoxide/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cellular+Senescence%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cellular Senescence/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Models%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Models, Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22DNA+Damage%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">DNA Damage/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%2c+Inbred+C57BL%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice, Inbred C57BL</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Organometallic+Compounds%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Organometallic Compounds/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Plasminogen+Activator+Inhibitor+1%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Plasminogen Activator Inhibitor 1/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pulmonary+Fibrosis%2fchemically+induced%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pulmonary Fibrosis/chemically induced</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pulmonary+Fibrosis%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pulmonary Fibrosis/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pulmonary+Fibrosis%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pulmonary Fibrosis/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pulmonary+Fibrosis%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pulmonary Fibrosis/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pulmonary+Fibrosis%2fprevention+%26amp%3b+control%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pulmonary Fibrosis/prevention & control</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Signal+Transduction%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Signal Transduction/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Tumor+Suppressor+Protein+p53%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Tumor Suppressor Protein p53/metabolism</a></li></ul> <a href="javascript:ShowArticleMeSH(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(19);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow20"> <td style="min-width: 40px; text-align: center;"> 20 </td> <td> <div id="citation20" class="article-citation"> <b>Yang G</b>, Ye J, Wang J, Liu H, Long Y, Jiang J, Miao X, Deng J, Wu T, Li T, Cheng X, Wang X. "Three birds, one stone" strategy of NIR-responsive CO/H<sub>2</sub>S dual-gas Nanogenerator for efficient treatment of osteoporosis. <em class='incite-journal-name' onclick='ShowInCiteJournal(16434);'>Mater Today Bio</em> 2024;<b>28</b>:101179. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39221209' target='_blank'>39221209</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11364908' target='_blank'>PMC11364908</a> DOI: <a href='https://dx.doi.org/10.1016/j.mtbio.2024.101179' target='_blank'>10.1016/j.mtbio.2024.101179</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.mtbio.2024.101179','39221209', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(20);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(20);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.mtbio.2024.101179' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://rcastoragev2.blob.core.windows.net/a5306e9890eab40a6e9fbf8c06e258a3/main.PMC11364908.pdf' target='_blank'>Download PDF</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="openf" onclick="OpenFigures('10.1016/j.mtbio.2024.101179');">Figures</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(16434);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/07/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/09/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 07/27/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/04/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv20" value="10.1016/j.mtbio.2024.101179" /> <div style="display: none" id="articleAbstract20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Osteoporosis (OP), the most prevalent bone degenerative disease, has become a significant public health challenge globally. Current therapies primarily target inhibiting osteoclast activity or stimulating osteoblast activation, but their effectiveness remains suboptimal. This paper introduced a "three birds, one stone" therapeutic approach for osteoporosis, employing upconversion nanoparticles (UCNPs) to create a dual-gas storage nanoplatform (UZPA-CP) targeting bone tissues, capable of concurrently generating carbon monoxide (CO) and hydrogen sulfide (H2S). Through the precise modulation of 808 nm near-infrared (NIR) light, the platform could effectively control the release of CO and H2S in the OP microenvironment, and realize the effective combination of promoting osteogenesis, inhibiting osteoclast activity, and improving the immune microenvironment to achieve the therapeutic effect of OP. High-throughput sequencing results further confirmed the remarkable effectiveness of the nanoplatform in inhibiting apoptosis, modulating inflammatory response, inhibiting osteoclast differentiation and regulating multiple immune signaling pathways. The gas storage nanoplatform not only optimized the OP microenvironment with the assistance of NIR, but also restored the balance between osteoblasts and osteoclasts. This comprehensive therapeutic strategy focused on improving the bone microenvironment, promoting osteogenesis and inhibiting osteoclast activity provides an ideal new solution for the treatment of metabolic bone diseases. </div> <a href="javascript:ShowArticleAbstract(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrogen+sulfide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrogen sulfide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Near-infrared+light%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Near-infrared light</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Osteoporosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Osteoporosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Upconversion+nanoparticles%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Upconversion nanoparticles</a></li></ul> <a href="javascript:ShowArticleKeywords(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(20);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow21"> <td style="min-width: 40px; text-align: center;"> 21 </td> <td> <div id="citation21" class="article-citation"> <b>Yang CH</b>, Wu CH, Luo KH, Chang HC, Wu SC, Chuang HY. Use of machine learning algorithms to determine the relationship between air pollution and cognitive impairment in Taiwan. <em>ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY</em> 2024;<b>284</b>:116885. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39151371' target='_blank'>39151371</a> DOI: <a href='https://dx.doi.org/10.1016/j.ecoenv.2024.116885' target='_blank'>10.1016/j.ecoenv.2024.116885</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.ecoenv.2024.116885','39151371', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(21);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(21);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(21);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.ecoenv.2024.116885' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 01/26/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/18/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/12/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 08/19/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv21" value="10.1016/j.ecoenv.2024.116885" /> <div style="display: none" id="articleAbstract21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Air pollution has become a major global threat to human health. Urbanization and industrialization over the past few decades have increased the air pollution. Plausible connections have been made between air pollutants and dementia. This study used machine learning algorithms (k-nearest neighbors, random forest, gradient-boosted decision trees, eXtreme gradient boosting, and CatBoost) to investigate the association between cognitive impairment and air pollution. Data from the Taiwan Biobank and 75 air-pollution-monitoring stations in Taiwan were analyzed to determine individual levels of exposure to air pollutants. The pollutants examined were particulate matter with a diameter of ≤ 2.5 μm (PM2.5), nitrogen dioxide, nitric oxide, carbon monoxide, and ozone. The results revealed that the most strongly correlated with cognitive impairment were ozone, PM2.5, and carbon monoxide levels with adjustment of educational level, age, and household income. The model based on these factors achieved accuracy as high as 0.97 for detecting cognitive impairment, indicating a positive association between air pollutions and cognitive impairment. </div> <a href="javascript:ShowArticleAbstract(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Air+pollution%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Air pollution</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cognitive+impairment%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cognitive impairment</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dementia%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dementia</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ozone%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ozone</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22PM(2.5)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">PM(2.5)</a></li></ul> <a href="javascript:ShowArticleKeywords(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Taiwan%2fepidemiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Taiwan/epidemiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Machine+Learning%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Machine Learning</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Air+Pollution%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Air Pollution/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Air+Pollution%2fstatistics+%26amp%3b+numerical+data%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Air Pollution/statistics & numerical data</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cognitive+Dysfunction%2fchemically+induced%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cognitive Dysfunction/chemically induced</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cognitive+Dysfunction%2fepidemiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cognitive Dysfunction/epidemiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Particulate+Matter%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Particulate Matter/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Air+Pollutants%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Air Pollutants/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Environmental+Monitoring%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Environmental Monitoring/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Algorithms%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Algorithms</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ozone%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ozone/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nitrogen+Dioxide%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nitrogen Dioxide/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+Monoxide%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon Monoxide/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nitric+Oxide%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nitric Oxide/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Environmental+Exposure%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Environmental Exposure</a></li></ul> <a href="javascript:ShowArticleMeSH(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(21);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow22"> <td style="min-width: 40px; text-align: center;"> 22 </td> <td> <div id="citation22" class="article-citation"> <b>Zhang Y</b>, Liu J, Hu M, Chai D, Zhang F, Yin T, Ye P, Fang Z, Zhang Y. The relationship between air pollution and the occurrence of hypertensive disorders of pregnancy: Evidence from a study in Wuhan, China. <em>ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY</em> 2024;<b>284</b>:116933. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39226864' target='_blank'>39226864</a> DOI: <a href='https://dx.doi.org/10.1016/j.ecoenv.2024.116933' target='_blank'>10.1016/j.ecoenv.2024.116933</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.ecoenv.2024.116933','39226864', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(22);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(22);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(22);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.ecoenv.2024.116933' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 12/27/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/05/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/21/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/05/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv22" value="10.1016/j.ecoenv.2024.116933" /> <div style="display: none" id="articleAbstract22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Ambient air pollution has been reported to be a risk factor for hypertensive disorders of pregnancy (HDP). Past studies have reported supportive evidence, but evidence from China is scarce and does not integrate the different periods of the pregnancy course. In this study, 1945 pregnant women with HDP and healthy pregnancies between 2016 and 2022 from the Renmin Hospital of Wuhan University registry network database were analysed. The geographic information, biological information and demographic information of the case were fused in the analysis. Machine learning methods were used to obtain the weight of the variable. Then, we used the generalized linear mixed model to evaluate the relationship between increased exposure to each pollutant at different periods of HDP and examined it in different groups. The results showed that SO2 had the predominate impact (12.65 %) on HDP compared with other air pollutants. SO2 exposure was associated with an increased risk of HDP. Increased unit SO2 concentrations were accompanied by an increased risk of HDP (OR = 1.33, 95 % CI: 1.13, 1.566), and the susceptible window for this effect was mainly in the first trimester (OR = 1.242, 95 % CI: 1.092, 1.412). In addition, SO2 exposure was associated with an increased risk of HDP in urban maternity (OR = 1.356, 95 % CI: 1.112, 1.653), obese maternity (OR = 3.58, 95 % CI: 1.608, 7.971), no higher education maternity (OR = 1.348, 95 % CI: 1.065, 1.706), nonzero delivery maternity (OR = 1.981, 95 % CI: 1.439, 2.725), maternal with first time maternity (OR = 1.247, 95 % CI: 1.007, 1.544) and other groups. In summary, SO2 exposure in early pregnancy is one of the risk factors for HDP, and the increased risk of HDP due to increased SO2 exposure may be more pronounced in obese, urban, low-education, and nonzero delivery populations. </div> <a href="javascript:ShowArticleAbstract(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypertensive+disorders%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypertensive disorders</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nitrogen+dioxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nitrogen dioxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ozone%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ozone</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Particulate+matter%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Particulate matter</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pregnancy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pregnancy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sulfur+dioxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sulfur dioxide</a></li></ul> <a href="javascript:ShowArticleKeywords(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pregnancy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pregnancy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22China%2fepidemiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">China/epidemiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Air+Pollution%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Air Pollution/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Air+Pollution%2fstatistics+%26amp%3b+numerical+data%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Air Pollution/statistics & numerical data</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Air+Pollutants%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Air Pollutants/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypertension%2c+Pregnancy-Induced%2fepidemiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypertension, Pregnancy-Induced/epidemiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypertension%2c+Pregnancy-Induced%2fchemically+induced%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypertension, Pregnancy-Induced/chemically induced</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sulfur+Dioxide%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sulfur Dioxide/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Risk+Factors%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Risk Factors</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Particulate+Matter%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Particulate Matter/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Environmental+Exposure%2fstatistics+%26amp%3b+numerical+data%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Environmental Exposure/statistics & numerical data</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Environmental+Exposure%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Environmental Exposure/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Young+Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Young Adult</a></li></ul> <a href="javascript:ShowArticleMeSH(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(22);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow23"> <td style="min-width: 40px; text-align: center;"> 23 </td> <td> <div id="citation23" class="article-citation"> <b>Shahraki J</b>, Tabrizian K, Rezaee R, Tashakori B, Dadrezaei S, Ghorani V, Bagheri G, Jahantigh H, Hashemzaei M. Hesperidin neuroprotective effects against <span class="highlight-field">carbon monoxide</span>-induced toxicity in male rats. <em>NAUNYN-SCHMIEDEBERG'S ARCHIVES OF PHARMACOLOGY</em> 2024;<b>397</b>:7673-7681. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38700797' target='_blank'>38700797</a> DOI: <a href='https://dx.doi.org/10.1007/s00210-024-03132-5' target='_blank'>10.1007/s00210-024-03132-5</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/s00210-024-03132-5','38700797', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(23);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(23);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(23);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(23);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1007/s00210-024-03132-5' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 11/18/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 04/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 08/04/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv23" value="10.1007/s00210-024-03132-5" /> <div style="display: none" id="articleAbstract23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Carbon monoxide (CO) is produced via incomplete combustion of fossil fuels and it may cause long-term neurological sequel upon exposure. Hesperidin (HES), a flavanone glycoside found in citrus plants, exerts diverse beneficial health effects. The present study mechanistically examined the neuroprotective effects of HES in CO-poisoned rats. Thirty male Wistar rats (five groups of six animals) were exposed to 3000 ppm CO for 1 h. Immediately after the exposure and on the next 4 consecutive days (totally five doses), rats intraperitoneally received either normal saline (the control group) or different doses of HES (25, 50, and 100 mg/kg). A sham group that was not exposed to CO was also considered. After evaluation of spatial learning and memory using a Morris water maze (MWM), animals were sacrificed and oxidative stress status in blood samples, and Akt, Bax, Bcl2, and brain-derived neurotrophic factor (BDNF) expression in brain samples were assessed. Western blot analysis indicated increased Akt but decreased Bax/Bcl2 levels in the HES 100 mg/kg, and induced BDNF levels in all HES-treated groups. MWM results showed that HES significantly decreased memory loss. The current findings indicate that HES could alleviate neurological impairments induced by CO in rats. </div> <a href="javascript:ShowArticleAbstract(23);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain-derived+neurotrophic+factor%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain-derived neurotrophic factor</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Herbal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Herbal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hesperidin%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hesperidin</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Natural+products%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Natural products</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neurotoxic%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neurotoxic</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Phytochemical%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Phytochemical</a></li></ul> <a href="javascript:ShowArticleKeywords(23);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh23" class="article-abstract"> <b style="display: block; 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padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Zabol+u%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">IR.ZBMU.REC.1399.031 Zabol u</a></li></ul> <a href="javascript:ShowArticleGrant(23);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow24"> <td style="min-width: 40px; text-align: center;"> 24 </td> <td> <div id="citation24" class="article-citation"> <b>Schelvis JPM</b>, Chen Z, Messina MA, Catalano J. Effect of CO binding to P450 BM3 F393 mutants on electron density distribution in the heme cofactor. <em class='incite-journal-name' onclick='ShowInCiteJournal(14342);'>J Inorg Biochem</em> 2024;<b>259</b>:112660. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39002177' target='_blank'>39002177</a> DOI: <a href='https://dx.doi.org/10.1016/j.jinorgbio.2024.112660' target='_blank'>10.1016/j.jinorgbio.2024.112660</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.jinorgbio.2024.112660','39002177', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(24);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(24);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(24);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.jinorgbio.2024.112660' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(14342);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 03/31/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 06/04/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 07/03/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 07/15/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv24" value="10.1016/j.jinorgbio.2024.112660" /> <div style="display: none" id="articleAbstract24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Resonance Raman spectroscopy has been performed on a set of cytochrome P450 BM3 heme domains in which mutation of the highly conserved Phe393 induces significant variation in heme iron reduction potential. In previous work [Chen, Z., Ost, T.W.B., and Schelvis, J.P.M. (2004) Biochemistry 43, 1798-1808], a correlation between heme vinyl conformation and the heme iron reduction potential indicated a steric control by the protein over the distribution of electron density in the reduced heme cofactor. The current study aims to monitor changes in electron density on the ferrous heme cofactor following CO binding. In addition, ferric-NO complexes have been studied to investigate potential changes to the proximal Cys400 thiolate. We find that binding of CO to the ferrous heme domains results in a reorientation of the vinyl groups to a largely out-of-plane conformation, the extent of which correlates with the size of the residue at position 393. We conclude that FeII dπ back bonding to the CO ligand largely takes away the need for conjugation of the vinyl groups with the porphyrin ring to accommodate FeII dπ back bonding to the porphyrin ligand. The ferrous-CO and ferric-NO data are consistent with a small decrease in σ-electron donation from the proximal Cys400 thiolate in the F393A mutant and, to a lesser extent, the F393H mutant, potentially due to a small increase in hydrogen bonding to the proximal ligand. Phe393 seems strategically placed to preserve robust σ-electron donation to the heme iron and to fine-tune its electron density by limiting vinyl group rotation. </div> <a href="javascript:ShowArticleAbstract(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cytochrome+P450+BM3%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cytochrome P450 BM3</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Heme+domain%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Heme domain</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nitric+oxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nitric oxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Resonance+Raman+spectroscopy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Resonance Raman spectroscopy</a></li></ul> <a href="javascript:ShowArticleKeywords(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Heme%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Heme/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Heme%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Heme/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cytochrome+P-450+Enzyme+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cytochrome P-450 Enzyme System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cytochrome+P-450+Enzyme+System%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cytochrome P-450 Enzyme System/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cytochrome+P-450+Enzyme+System%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cytochrome P-450 Enzyme System/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+Monoxide%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon Monoxide/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+Monoxide%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon Monoxide/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Spectrum+Analysis%2c+Raman%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Spectrum Analysis, Raman</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bacterial+Proteins%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bacterial Proteins/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bacterial+Proteins%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bacterial Proteins/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bacterial+Proteins%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bacterial Proteins/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NADPH-Ferrihemoprotein+Reductase%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">NADPH-Ferrihemoprotein Reductase/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NADPH-Ferrihemoprotein+Reductase%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">NADPH-Ferrihemoprotein Reductase/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NADPH-Ferrihemoprotein+Reductase%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">NADPH-Ferrihemoprotein Reductase/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Protein+Binding%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Protein Binding</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mutation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mutation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nitric+Oxide%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nitric Oxide/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nitric+Oxide%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nitric Oxide/chemistry</a></li></ul> <a href="javascript:ShowArticleMeSH(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(24);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow25"> <td style="min-width: 40px; text-align: center;"> 25 </td> <td> <div id="citation25" class="article-citation"> <b>Roberts MG</b>, Dent MR, Ramos S, Thielges MC, Burstyn JN. Probing conformational dynamics of DNA binding by CO-sensing transcription factor, CooA. <em class='incite-journal-name' onclick='ShowInCiteJournal(14342);'>J Inorg Biochem</em> 2024;<b>259</b>:112656. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38986290' target='_blank'>38986290</a> DOI: <a href='https://dx.doi.org/10.1016/j.jinorgbio.2024.112656' target='_blank'>10.1016/j.jinorgbio.2024.112656</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.jinorgbio.2024.112656','38986290', 'Carbon monoxide')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(25);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(25);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(25);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.jinorgbio.2024.112656' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(14342);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 04/16/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 05/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 06/27/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 07/12/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv25" value="10.1016/j.jinorgbio.2024.112656" /> <div style="display: none" id="articleAbstract25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">The transcription factor CooA is a CRP/FNR (cAMP receptor protein/ fumarate and nitrate reductase) superfamily protein that uses heme to sense carbon monoxide (CO). Allosteric activation of CooA in response to CO binding is currently described as a series of discrete structural changes, without much consideration for the potential role of protein dynamics in the process of DNA binding. This work uses site-directed spin-label electron paramagnetic resonance spectroscopy (SDSL-EPR) to probe slow timescale (μs-ms) conformational dynamics of CooA with a redox-stable nitroxide spin label, and IR spectroscopy to probe the environment at the CO-bound heme. A series of cysteine substitution variants were created to selectively label CooA in key functional regions, the heme-binding domain, the 4/5-loop, the hinge region, and the DNA binding domain. The EPR spectra of labeled CooA variants are compared across three functional states: Fe(III) "locked off", Fe(II)-CO "on", and Fe(II)-CO bound to DNA. We observe changes in the multicomponent EPR spectra at each location; most notably in the hinge region and DNA binding domain, broadening the description of the CooA allosteric mechanism to include the role of protein dynamics in DNA binding. DNA-dependent changes in IR vibrational frequency and band broadening further suggest that there is conformational heterogeneity in the active WT protein and that DNA binding alters the environment of the heme-bound CO. </div> <a href="javascript:ShowArticleAbstract(25);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Allostery%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Allostery</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+monoxide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon monoxide</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Heme%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Heme</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Protein+dynamics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Protein dynamics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Transcriptional+regulation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Transcriptional regulation</a></li></ul> <a href="javascript:ShowArticleKeywords(25);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Electron+Spin+Resonance+Spectroscopy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Electron Spin Resonance Spectroscopy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+Monoxide%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon Monoxide/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbon+Monoxide%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbon Monoxide/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bacterial+Proteins%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bacterial Proteins/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bacterial+Proteins%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bacterial Proteins/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22DNA%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">DNA/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22DNA%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">DNA/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Heme%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Heme/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Heme%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Heme/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Protein+Binding%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Protein Binding</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Protein+Conformation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Protein Conformation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Allosteric+Regulation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Allosteric Regulation</a></li><li><a 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class="dxWeb_pNext_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Next" /></a> </div><b class="dx-clear"></b><script id="dxss_1724423056" type="text/javascript">  </script> </div> </div> <div class="cl"></div> </div> </div> </div> <table class="dxlpLoadingPanel_MetropolisBlue dxlpControl_MetropolisBlue" id="RootHolder_LeftLoadingPanel" style="position:absolute;left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="text-align:Center;vertical-align:Top;"><span id="RootHolder_LeftLoadingPanel_TL">Loading…</span></td> </tr> </table><div id="RootHolder_LeftLoadingPanel_LD" class="dxlpLoadingDiv_MetropolisBlue dxlpControl_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1950550554" type="text/javascript">  </script> <div id="RootHolder_articleCitationPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:450px;width:600px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv 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<span class="dxpc-headerText dx-vam"></span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content" style="overflow-x:hidden;overflow-y:scroll;">    </div> </div> </div> </div><div id="RootHolder_chartPopupControl_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_chartPopupControl_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_chartPopupControl_TL">Loading…</span></td> </tr> </table><div id="RootHolder_chartPopupControl_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_420552910" type="text/javascript">  </script> <div id="RootHolder_pcImportArticlesControl_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:50px;width:50px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_pcImportArticlesControl_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Import Articles</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="RootHolder_pcImportArticlesControl_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_pcImportArticlesControl_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_pcImportArticlesControl_TL">Loading…</span></td> </tr> </table><div id="RootHolder_pcImportArticlesControl_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_365297802" type="text/javascript">  </script> <div id="RootHolder_pcEditArticleControl_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_pcEditArticleControl_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Edit My Journal Article</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content" style="overflow-x:hidden;overflow-y:scroll;">    </div> </div> </div> </div><div id="RootHolder_pcEditArticleControl_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_pcEditArticleControl_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_pcEditArticleControl_TL">Loading…</span></td> </tr> </table><div id="RootHolder_pcEditArticleControl_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_298765222" type="text/javascript">  </script> <div id="RootHolder_userIndexComputePopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:200px;width:400px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header dxpc-withBtn" style="font-size:20px;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Article Influence Index</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="ai-content-container"> <p> <b>Calculation for <span id="RootHolder_userIndexComputePopup_InfluenceIndexTitle2">Article Influence Index</span></b> </p> <p> Total Citations in Crossref ÷ Total Articles = <span id="RootHolder_userIndexComputePopup_InfluenceIndexTitle3">Article Influence Index</span><sup class="standard-yellow">TM</sup> </p> </div> </div> </div> </div> </div><table id="RootHolder_userIndexComputePopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_userIndexComputePopup_TL">Loading…</span></td> </tr> </table><div id="RootHolder_userIndexComputePopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1286575841" type="text/javascript">  </script> <div id="RootHolder_articleExportPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:280px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow" style="font-size:11pt;"> <div class="dxpc-header drag dxpc-withBtn" style="font-size:20px;user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_articleExportPopup_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Export Articles to File</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="dxtcLite_MetropolisBlue dxtcSys dxtc-init dxtc-top dxtc-pc" id="RootHolder_articleExportPopup_ExportFilePageControl" style="width:100%;"> <ul class="dxtc-strip dxtc-row dxtc-stripContainer"> <li class="dxtc-leftIndent"> </li><li class="dxtc-tab dxtc-lead" style="display:none;"><a class="dxtc-link"><span class="dx-vam">Export Article Detail</span></a></li><li class="dxtc-activeTab dxtc-lead"><a class="dxtc-link"><span class="dx-vam">Export Article Detail</span></a></li><li class="dxtc-spacer"> </li><li class="dxtc-tab dxtc-last"><a class="dxtc-link"><span class="dx-vam">Export Citation Analysis</span></a></li><li class="dxtc-activeTab dxtc-last" style="display:none;"><a class="dxtc-link"><span class="dx-vam">Export Citation Analysis</span></a></li><li class="dxtc-rightIndent"> </li> </ul><div class="dxtc-content"> <div> <div> <div class="dxflFormLayout_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout" style="font-size:11pt;width:100%;"> <table class="dxflGroup_MetropolisBlue dxflGroupSys dxflAGSys" style="border-collapse:separate;"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_0" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_0_Cap" class="dxDefaultCursor dxflCaption_MetropolisBlue" style="font-weight:bold;">Searched Name:</span></td><td class="dxflNestedControlCell_MetropolisBlue"> <span class="dxeBase_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_SearchTermText1">Carbon monoxide (780 results from Reference Citation Analysis)</span> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_1" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="padding-bottom:5px;"> <table> <tr> <td> <span style="font-weight: bold">Article Number From</span> </td> <td>   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ExportDetailStartIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" value="1" type="text" /></td> </tr> </table><script id="dxss_1662381219" type="text/javascript">  </script> </td> <td>  to   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ExportDetailEndIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" value="600" type="text" /></td> </tr> </table><script id="dxss_616434442" type="text/javascript">  </script> </td> <td>  </td> <td>(No more than 600 records at a time.) </td> </tr> </table> </div></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_2" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_I" style="font-weight:bold;">Indexing:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$selectDetailSource" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-100" class="dxeButton dxeButtonEditButton_MetropolisBlue dxeButtonEditClearButton_MetropolisBlue" onmousedown="ASPx.BEClear('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="display:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-100Img" class="dxEditors_edtClear_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="x" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$selectDetailSource$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr> <td></td> </tr> </table> </div></td> </tr> </table><script id="dxss_1167331127" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_54524200" type="text/javascript">  </script><script id="dxss_1678130197" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_4" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_I" style="font-weight:bold;">JCR Year:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_VI" type="hidden" value="2023" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$JCRYear" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" value="2023" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$JCRYear$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2023</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2022</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2021</td> </tr> </table> </div></td> </tr> </table><script id="dxss_830317689" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_167955898" type="text/javascript">  </script><script id="dxss_2013408041" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_5" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_I" style="font-weight:bold;">Format:</label><em class="dxflRequired_MetropolisBlue">*</em></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_ET" class="dxeValidDynEditorTable dxeRoot_MetropolisBlue"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_CC"><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat" style="width:200px;border-collapse:separate;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$DetailFileFormat" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$DetailFileFormat$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Excel</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Plain Text</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">PDF</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">WORD</td> </tr> </table> </div></td> </tr> </table><script id="dxss_1062639383" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_104403608" type="text/javascript">  </script></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_EC" class="dxeErrorCell_MetropolisBlue dxeErrorFrame_MetropolisBlue dxeErrorFrameSys dxeErrorCellSys dxeNoBorderLeft" style="vertical-align:middle;display:none;white-space:nowrap;">Invalid value</td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1973673553" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_6" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLTSys dxflItemSys dxflCheckBoxWithTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields_S" style="font-weight:bold;">Record Content:</label></td> </tr><tr> <td class="dxflNestedControlCell_MetropolisBlue"> <table> <tr> <td style="vertical-align: middle; padding: 5px;"> <table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields" style="color:#BD4100;"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields_S" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$cbSelectAllFields" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label>Select All Fields</label></td> </tr> </table><script id="dxss_1176833720" type="text/javascript">  </script> </td> </tr> <tr> <td style="padding: 5px;"> <table class="dxeCheckBoxList_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields" style="width:100%;border-collapse:separate;"> <tr> <td class="dxe"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields" /><table style="width:100%;"> <tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB0"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB0_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB0" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Author(s)</label></td> </tr> </table><script id="dxss_771536870" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB1"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB1_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB1" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Article Title</label></td> </tr> </table><script id="dxss_1086331335" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB2"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB2_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB2" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Keywords</label></td> </tr> </table><script id="dxss_1308541020" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB3"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB3_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB3" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">MESH Headings</label></td> </tr> </table><script id="dxss_896786043" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB4"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB4_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB4" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Journal Title</label></td> </tr> </table><script id="dxss_450242410" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB5"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB5_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB5" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Year</label></td> </tr> </table><script id="dxss_765036875" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB6"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB6_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB6" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Article Type</label></td> </tr> </table><script id="dxss_1629835480" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB7"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB7_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB7" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Language</label></td> </tr> </table><script id="dxss_1218080503" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB8"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB8_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB8" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Published Date</label></td> </tr> </table><script id="dxss_1428514578" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB9"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB9_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB9" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">First Author</label></td> </tr> </table><script id="dxss_1113720113" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB10"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB10_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB10" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">First Author’s Affiliations</label></td> </tr> </table><script id="dxss_310841941" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB11"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB11_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB11" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Corresponding Author</label></td> </tr> </table><script id="dxss_1301541094" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB12"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB12_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB12" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Corresponding Author’s Affiliations</label></td> </tr> </table><script id="dxss_675718561" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB13"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB13_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB13" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Email</label></td> </tr> </table><script id="dxss_2006865700" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB14"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB14_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB14" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">All Authors's Affiliations</label></td> </tr> </table><script id="dxss_1204905793" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB15"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB15_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB15" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Grant</label></td> </tr> </table><script id="dxss_407477242" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB16"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB16_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB16" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">ISSN</label></td> </tr> </table><script id="dxss_218345291" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB17"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB17_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB17" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Publisher</label></td> </tr> </table><script id="dxss_1394037744" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB18"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB18_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB18" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Indexing / Abstracting</label></td> </tr> </table><script id="dxss_319681069" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB19"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB19_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB19" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Impact Factor</label></td> </tr> </table><script id="dxss_1292701966" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB20"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB20_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB20" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">JCR Quartile</label></td> </tr> </table><script id="dxss_1844280938" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB21"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB21_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB21" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Impact Index Per Article</label></td> </tr> </table><script id="dxss_838303323" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB22"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB22_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB22" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Category</label></td> </tr> </table><script id="dxss_1464125856" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB23"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB23_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB23" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Times Cited in RCA</label></td> </tr> </table><script id="dxss_148257179" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB24"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB24_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB24" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Peer-Reviewed Journal</label></td> </tr> </table><script id="dxss_950217086" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB25"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB25_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB25" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Open Access</label></td> </tr> </table><script id="dxss_1732367175" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB26"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB26_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB26" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">DOI</label></td> </tr> </table><script id="dxss_1936777588" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB27"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB27_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB27" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">PMID</label></td> </tr> </table><script id="dxss_745806673" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB28"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB28_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB28" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Citation</label></td> </tr> </table><script id="dxss_1835441810" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB29"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB29_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB29" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Indexed in RCA</label></td> </tr> </table><script id="dxss_847142451" type="text/javascript">  </script></td><td></td><td></td> </tr> </table></td> </tr> </table><script id="dxss_1169734383" type="text/javascript">  </script> </td> </tr> </table> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_7" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue"> <a class="dxeHyperlink_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportedDetailFileLink" target="_blank" rel="noopener noreferrer">Click to Download the Exported File</a><script id="dxss_1198171345" type="text/javascript">  </script> </div></td> </tr> </table> </div><script id="dxss_1960175520" type="text/javascript">  </script> </div> </div><div style="display:none;"> <div> <div class="dxflFormLayout_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout" style="font-size:11pt;width:100%;"> <table class="dxflGroup_MetropolisBlue dxflGroupSys dxflAGSys" style="border-collapse:separate;"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_0" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_0_Cap" class="dxDefaultCursor dxflCaption_MetropolisBlue" style="font-weight:bold;">Searched Name:</span></td><td class="dxflNestedControlCell_MetropolisBlue"> <span class="dxeBase_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_SearchTermText2">Carbon monoxide (780 results from Reference Citation Analysis)</span> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_1" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="padding-bottom:10px;"> <table> <tr> <td> <span style="font-weight: bold">Article Number From</span> </td> <td>   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$ExportStartIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" value="1" type="text" /></td> </tr> </table><script id="dxss_814491935" type="text/javascript">  </script> </td> <td>  to   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$ExportEndSIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" value="600" type="text" /></td> </tr> </table><script id="dxss_1331245653" type="text/javascript">  </script> </td> <td>  </td> <td>(No more than 600 records at a time.) </td> </tr> </table> </div></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_2" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:10px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_I" style="font-weight:bold;">Indexing:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$selectSource" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-100" class="dxeButton dxeButtonEditButton_MetropolisBlue dxeButtonEditClearButton_MetropolisBlue" onmousedown="ASPx.BEClear('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="display:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-100Img" class="dxEditors_edtClear_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="x" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$selectSource$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr> <td></td> </tr> </table> </div></td> </tr> </table><script id="dxss_2046065225" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_1926633208" type="text/javascript">  </script><script id="dxss_228619664" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_4" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:20px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_I" style="font-weight:bold;">Format:</label><em class="dxflRequired_MetropolisBlue">*</em></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_ET" class="dxeValidDynEditorTable dxeRoot_MetropolisBlue"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_CC"><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat" style="width:200px;border-collapse:separate;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_VI" type="hidden" value="1" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$FileFormat" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" value="Excel" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$FileFormat$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Excel</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Plain Text</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">PDF</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">WORD</td> </tr> </table> </div></td> </tr> </table><script id="dxss_1509722775" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_960798088" type="text/javascript">  </script></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_EC" class="dxeErrorCell_MetropolisBlue dxeErrorFrame_MetropolisBlue dxeErrorFrameSys dxeErrorCellSys dxeNoBorderLeft" style="vertical-align:middle;display:none;white-space:nowrap;">Invalid value</td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_835950349" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_5" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue"> <a class="dxeHyperlink_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportedFileLink" target="_blank" rel="noopener noreferrer">Click to Download the Exported File</a><script id="dxss_308093146" type="text/javascript">  </script> </div></td> </tr> </table> </div><script id="dxss_424125632" type="text/javascript">  </script> </div> </div> </div> </div><b class="dx-clear"></b><table id="RootHolder_articleExportPopup_ExportFilePageControl_LP" class="dxtcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_TL">Loading…</span></td> </tr> </table><script id="dxss_2124675053" type="text/javascript">  </script> </div> </div><div class="dxpc-footer"> <div class="popup-footer-button-container"> <div class="dxbButton_MetropolisBlue DefaultButton dxbButtonSys dxbTSys" id="RootHolder_articleExportPopup_TPCFm1_btnExportArticles" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxb"> <input id="RootHolder_articleExportPopup_TPCFm1_btnExportArticles_I" class="dxb-hb" value="Export" type="submit" name="ctl00$RootHolder$articleExportPopup$TPCFm1$TC$btnExportArticles" /><span class="dx-vam">Export</span> </div> </div><script id="dxss_77486387" type="text/javascript">  </script>    <div class="dxbButton_MetropolisBlue DefaultButton dxbButtonSys dxbTSys" id="RootHolder_articleExportPopup_TPCFm1_btnCancel" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxb"> <input id="RootHolder_articleExportPopup_TPCFm1_btnCancel_I" class="dxb-hb" value="Cancel" type="submit" name="ctl00$RootHolder$articleExportPopup$TPCFm1$TC$btnCancel" /><span class="dx-vam">Cancel</span> </div> </div><script id="dxss_2118985763" type="text/javascript">  </script> </div> </div> </div> </div><div id="RootHolder_articleExportPopup_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_articleExportPopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="font-size:11pt;left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="font-size:11pt;padding-left:0px;"><span id="RootHolder_articleExportPopup_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_578446409" type="text/javascript">  </script> </div> <div class="bottom-part cl"> © 2004-2024 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA </div> <div class="scroll"> <a href="#top" target="_self"> <img src="/Contents/Images/backtop3.png" /> </a> </div> <div id="categorySelectorPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="font-size:20px;user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Select the Category</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="categorySelectorPopup_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="categorySelectorPopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="categorySelectorPopup_TL">Loading…</span></td> </tr> </table><div id="categorySelectorPopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_166253781" type="text/javascript">  </script> <div id="pcLoginPopUp_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:700px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="pcLoginPopUp_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="pcLoginPopUp_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="pcLoginPopUp_TL">Loading…</span></td> </tr> </table><div id="pcLoginPopUp_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_430910140" type="text/javascript">  </script> <div id="aiComputePopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:200px;width:300px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header dxpc-withBtn" style="font-size:20px;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Impact Index Per Article</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="ai-content-container"> <p> <b>Calculation for Impact Index Per Article</b> </p> <p> Times Cited ÷ Number of Years = Impact Index Per Article<sup class="standard-yellow">TM</sup> </p> </div> </div> </div> </div> </div><table id="aiComputePopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="aiComputePopup_TL">Loading…</span></td> </tr> </table><div id="aiComputePopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_698179129" type="text/javascript">  </script> <script type="text/javascript"> //<![CDATA[ var callBackFrameUrl='/WebResource.axd?d=beToSAE3vdsL1QUQUxjWdX-3aFLejnBliGvqSCZYULGFdxZmRlcJcqs71AKVNTQEXljNmd0slFkUZ_AFaCke4Q2&t=638628207619783110'; WebForm_InitCallback();//]]> </script> </form> </body> </html>