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Knowledge HQ - ScaleReady

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hide-for-small-only"><input class="button extra-small mb-0 ff-pnsb" type="submit" value="Submit"></div> <div class="resource-search-reset columns shrink hide-for-small-only"><input class="button extra-small mb-0 has-border ff-pnsb" type="reset" value="Reset"></div> </div> <div class="resource-type-filter type-filter mb-50 position-relative"> <div class="small-filter text-24-29 ff-pnsb position-relative color-white show-for-small-only" id="show-filter"> All </div> <ul class="category-filters no-bullet mb-0"> <li class="category-filter filter-list "> <a class="text-24-29 display-block ff-pnsb" href="/knowledge-hq/" data-term-id="">All</a> </li> <li class="category-filter filter-list "> <a class="text-24-29 display-block ff-pnsb" href="/knowledge-hq/application-notes" data-term-id="application-notes">Application Notes</a> </li> <li class="category-filter filter-list "> <a class="text-24-29 display-block ff-pnsb" href="/knowledge-hq/case-studies" data-term-id="case-studies">Case Studies</a> </li> <li class="category-filter filter-list "> <a class="text-24-29 display-block ff-pnsb" href="/knowledge-hq/literature" data-term-id="literature">Literature</a> </li> <li class="category-filter filter-list "> <a class="text-24-29 display-block ff-pnsb" href="/knowledge-hq/protocols" data-term-id="protocols">Protocols</a> </li> <li class="category-filter filter-list "> <a class="text-24-29 display-block ff-pnsb" href="/knowledge-hq/scientific-posters" data-term-id="scientific-posters">Scientific Posters</a> </li> <li class="category-filter filter-list "> <a class="text-24-29 display-block ff-pnsb" href="/knowledge-hq/videos" data-term-id="videos">Videos</a> </li> <li class="category-filter filter-list "> <a class="text-24-29 display-block ff-pnsb" href="/knowledge-hq/webinar" data-term-id="webinar">Webinars</a> </li> <li><a class="text-24-29 display-block ff-pnsb" href="/insights">Insights</a></li> </ul> </div> </div> <div class="product-list-wrapper row"> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2022/01/Resource-web-thumbnails-Casestudy-4.jpg"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> Case Studies, LOVO </div> <h2 class="h4 title color-navy-blue mb-25"> Lovo Integral to COVID-19 Lung Fibrosis Clinical Trial </h2> <div class="text-18-24 mb-50"> In this case study we interview Arindam Mitra, Head of Advanced Therapies Manufacturing at Guy's and St. Thomas, Biomedical Research Center, on their use of the Lovo cell processing system to support manufacturing of a COVID-19 cell therapy to treat lung fibrosis. This cell therapy is currently in clinical trials. A BBC video describing the manufacturing procedure and treatment impact on one patient is included. </div> </div> <a target="_blank" class="button small mb-0" href="https://live-scaleready.pantheonsite.io/lovo-integral-to-manufacturing-phase-1-clinical-trials-for-monaco-2/">Read More</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2022/01/Resource-web-thumbnails-IL7.jpg"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> Literature </div> <h2 class="h4 title color-navy-blue mb-25"> Recombinant Human IL-7 GMP </h2> <div class="text-18-24 mb-50"> GMP-grade Recombinant Human IL-7 can now be produced at a game-changing scale within Bio-Techne’s new dedicated animal-free GMP facility. This flyer details manufacturing benefits and product specifications for GMP IL-7, including comparison to animal-free research-grade rhIL-7 to enable a seamless transition to GMP. </div> </div> <a target="_blank" class="button small mb-0" href="https://www.scaleready.com/resource/recombinant-human-il-7-gmp/">Download</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2021/11/Resource-web-thumbnails-Casestudy-GRex-optimization.jpg"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> Case Studies </div> <h2 class="h4 title color-navy-blue mb-25"> Transition to Closed-system T Cell Expansion Leads to Process Optimization </h2> <div class="text-18-24 mb-50"> In this case study, ScaleReady helped an autologous T cell therapy company rapidly transition to a closed-system process for cell expansion by providing a testing plan to verify that G-Rex500M-CS closed-system bioreactors would meet their immediate cell production requirements and improve cell production efficiency, while adhering to their short timelines for going into clinical trials. In doing so, the company also uncovered small changes to their cell culture protocols that made a big impact on their cell production efficiency. </div> </div> <a target="_blank" class="button small mb-0" href="https://www.scaleready.com/resource/transition-to-closed-system-t-cell-expansion-leads-to-process-optimization/">Download</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2021/11/Resource-web-thumbnails-Casestudy-GRex-forecasting.jpg"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> Case Studies </div> <h2 class="h4 title color-navy-blue mb-25"> Forecasting a Commercially Viable T Cell Therapy Manufacturing Process </h2> <div class="text-18-24 mb-50"> In this case study, a company requested help from ScaleReady to build business case for G-Rex®500M-CS bioreactors as the primary cell production platform for their autologous TCR T cell therapy pipeline. ScaleReady modeled operational costs for an autologous TCR T cell therapy company using G-Rex bioreactors. This provided transparency into long-term commercial viability of the ScaleReady platform. </div> </div> <a target="_blank" class="button small mb-0" href="https://www.scaleready.com/resource/forecasting-a-commercially-viable-t-cell-therapy-manufacturing-process/">Download</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2021/11/Resource-web-thumbnails-Casestudy-GMP.jpg"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> Case Studies </div> <h2 class="h4 title color-navy-blue mb-25"> GMP Cytokines Optimization for Closed System T Cell Therapy Manufacturing </h2> <div class="text-18-24 mb-50"> In this case study, a company focused on autologous T cell therapies targeting solid tumor cancers was progressing into clinical trials and needed to transition from research-grade to GMP-grade cytokines. Concurrently they wanted to improve their methods of cytokine supplementation to reduce cytokine waste, improve dose accuracy across lots, and reduce process risk by defining methods for closed-system cytokine addition. ScaleReady detailed a plan to help them achieve these goals. </div> </div> <a target="_blank" class="button small mb-0" href="https://www.scaleready.com/resource/gmp-cytokines-optimization-for-closed-system-t-cell-therapy-manufacturing/">Download</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/Resource-web-thumbnails-webinar.png"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> Videos </div> <h2 class="h4 title color-navy-blue mb-25"> Future of T Cell Manufacturing using G-Rex Closed-system Bioreactors </h2> <div class="text-18-24 mb-50"> This video animation demonstrates a vision toward the industrialization and automation of T cell therapy manufacturing using G-Rex Bioreactors.<br><br><em>Video was created by Wilson Wolf Manufacturing Corporation.</em> </div> </div> <a target="_blank" class="button small mb-0" href="https://youtu.be/wQXGVymespo">Watch Video</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/Resource-web-thumbnails-Batch1-10.jpg"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> Literature </div> <h2 class="h4 title color-navy-blue mb-25"> G-Rex Closed-system Bioreactors </h2> <div class="text-18-24 mb-50"> In this brochure you will learn how G-Rex bioreactors solve the limitations of flask and bag-based cell therapy manufacturing. In this brochure: <ul> <li>G-Rex Bioreactor mechanism of action</li> <li>Benefits for cell therapy manufacturing</li> <li>GatheRex Cell Harvest Pump</li> <li>User testimonials</li> </ul> </div> </div> <a target="_blank" class="button small mb-0" href="https://www.scaleready.com/resource/g-rex-revolutionizing-cell-therapy-manufacturing-2/">Download</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/Resource-web-thumbnails-webinar.png"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> Videos </div> <h2 class="h4 title color-navy-blue mb-25"> G-Rex – Revolutionizing Cell Therapy Manufacturing </h2> <div class="text-18-24 mb-50"> <div></div> In this video you will learn how G-Rex bioreactors solve the limitations of flask and bag-based cell therapy manufacturing. By providing cells with uninterrupted access to oxygen and nutrients, the G-Rex cell culture device is the only accessible cell expansion technology that linearly scales to meet the demands of cell therapy manufacturers. </div> </div> <a target="_blank" class="button small mb-0" href="https://youtu.be/tpuOklz60yQ">Watch Video</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/Resource-web-thumbnails-webinar.png"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> Videos </div> <h2 class="h4 title color-navy-blue mb-25"> On Demand Symposium: Defining Intelligent Scale-up and Scale-out </h2> <div class="text-18-24 mb-50"> <div>In this recorded symposium, cell therapy manufacturing leaders speak about defining and planning for intelligent commercial scale up and scale out. Recorded at ISCT 2021.</div> </div> </div> <a target="_blank" class="button small mb-0" href="https://www.youtube.com/watch?v=MJ1J52zFDsg&t=1324s">Watch Symposium</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/Resource-web-thumbnails-Batch1-9.jpg"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> CUE, Literature </div> <h2 class="h4 title color-navy-blue mb-25"> Cell Processing Systems Comparison Flyer </h2> <div class="text-18-24 mb-50"> <div>Compare Lovo and Cue system specifications and applications.</div> </div> </div> <a target="_blank" class="button small mb-0" href="https://www.scaleready.com/resource/cell-processing-systems-comparison-flyer/">Download</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/Resource-web-thumbnails-Batch1-7.jpg"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> Literature </div> <h2 class="h4 title color-navy-blue mb-25"> TcBuster Non-viral Genetic Engineering Flyer </h2> <div class="text-18-24 mb-50"> <div> TcBuster non-viral gene editing solves the bottlenecks facing viral vector-based editing, including supply chain, manufacturing time, and integration safety. In this flyer: <ul> <li>How TcBuster works</li> <li>Comparison to viral tranduction</li> <li>Data on transposition efficiency and scalability</li> </ul> </div> </div> </div> <a target="_blank" class="button small mb-0" href="https://www.scaleready.com/resource/tcbuster-non-viral-genetic-engineering-flyer/">View Flyer</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/Resource-web-thumbnails-Batch1-5.jpg"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> Literature </div> <h2 class="h4 title color-navy-blue mb-25"> ExCellerate Media for Immune Cells </h2> <div class="text-18-24 mb-50"> This flyer provides details and data for our T cell and NK cell versions of ExCellerate media. </div> </div> <a target="_blank" class="button small mb-0" href="https://www.scaleready.com/resource/excellerate-immune-cell-culture-media-flyer/">Read Flyer</a> </div> </div> </div> </div> <div class="row align-center ptb-80 padding-top-0"> <div class="columns shrink pagination color-white flex-container"> <a aria-label="Next Previous" class="prev page-numbers" href="https://www.scaleready.com/knowledge-hq/page/3/"></a> <a aria-label="Next Previous" class="page-numbers" href="https://www.scaleready.com/knowledge-hq/page/1/">1</a> <a aria-label="Next Previous" class="page-numbers" href="https://www.scaleready.com/knowledge-hq/page/2/">2</a> <a aria-label="Next Previous" class="page-numbers" href="https://www.scaleready.com/knowledge-hq/page/3/">3</a> <span aria-current="page" class="page-numbers current">4</span> <a aria-label="Next Previous" class="page-numbers" href="https://www.scaleready.com/knowledge-hq/page/5/">5</a> <a aria-label="Next Previous" class="next page-numbers" href="https://www.scaleready.com/knowledge-hq/page/5/"></a> </div> </div> </div> </div></div></div></div> </div> </div> </div> </div> </div> <div> </div> </article> </main> <footer class="footer color-white"> <div class="row position-relative zIndex-2"> <div class="columns small-12"> <section id="custom_html-2" class="widget_text widget widget_custom_html"><div class="textwidget custom-html-widget"><div class="row align-middle footer-top"> <div class="columns"> <div class="f-logo"> <img src="/wp-content/uploads/2021/08/Logo-White.png" alt="ScaleReady"> </div> </div> <div class="columns shrink flex-container"> <div class="ff-barlow fw-500 text"> <div class="fw-700">General Inquiries:</div> <a href="mailto:info@scaleready.com">info@scaleready.com</a> </div> <div class="ff-barlow fw-500 text"> <div class="fw-700">Career Opportunities:</div> <a href="mailto:careers@scaleready.com">careers@scaleready.com</a> </div> </div> </div> <hr /></div></section><section id="custom_html-3" class="widget_text widget widget_custom_html"><div class="textwidget custom-html-widget"><div class="row align-middle footer-middle"> <div class="columns"> <a class="f-social" href="https://www.linkedin.com/company/wearescaleready" title="Visit ScaleReady on LinkedIn" target="_blank" rel="noopener"> <img src="/wp-content/uploads/2021/08/Linkedin-Logo.png" alt="LinkedIn"> </a> </div> <div class="columns shrink flex-container"> <div class="ff-barlow fw-700 text"><a href="/terms-of-use">Terms of Use</a></div> <div class="ff-barlow fw-700 text"><a href="/privacy-policy">Privacy Policy</a></div> </div> </div></div></section><section id="text-2" class="widget widget_text"> <div class="textwidget"><div class="text-18-24 copyright">© 2024 ScaleReady USA</div> </div> </section> </div> </div> </footer> </div><!-- Close off-canvas content --> <!-- HFCM by 99 Robots - Snippet # 4: Pardot First-Party Tracking --> <script type='text/javascript'> piAId = '976203'; piCId = ''; piHostname = 'go.scaleready.com'; (function() { function async_load(){ var s = document.createElement('script'); s.type = 'text/javascript'; s.src = ('https:' == document.location.protocol ? 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