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</div> </header> <main class="main-content"> <article id="post-7295" class="post-7295 product type-product status-publish hentry product_category-gene-editing"> <div class="page-title-wrap intro-section hide"> <div class="row"> <h1 class="columns mb-0 entry-title">TcBuster™ Non-viral Gene Delivery System for Cell and Gene Therapy</h1> </div> </div> <div class="entry-content"> <div class="st-lazy-load-bg bg-cover p-intro intro-section position-relative zIndex-2 " data-src='https://www.scaleready.com/wp-content/uploads/2021/09/Group-214.png'> <div class="row"> <div class="columns small-12"> <div class="h1"> <p>TcBuster™ non-viral gene delivery system for cell and gene therapy</p> </div> <div class="single-link h4 small-text-24-32 smb-0 mt-30"> <a href="https://live-scaleready.pantheonsite.io/product/tcbuster-non-viral-gene-engineering-system/#tcbuster_form" target="" >Request a Consultation ></a> </div> </div> </div> </div> <div class="row"> <div class="columns small-12"> <div class="sr-main-content"> <div class="wpb-content-wrapper"><div class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="sr_full_width_content section-50-wrapper st-lazy-load-bg bg-cover" data-src='https://www.scaleready.com/wp-content/uploads/2021/09/Group-227.png'> <div class="corner-image bottom-right"> <img decoding="async" src="https://www.scaleready.com/wp-content/uploads/2021/09/figure-cell-4.png" alt="figure-cell-4"> </div> <div class="section-50-items position-relative zIndex-4"> <div class="small-collapse-section"> <div class="row align-middle section-50-item "> <div class="columns small-12 medium-6 "> <div class="position-relative"> <div class="revealator-zoomin rev-item"></div> <div class="img-wrapper zi"> <a href="https://www.scaleready.com/product/tcbuster-non-viral-gene-engineering-system/#tcbuster_form" target=""> <img class="st-lazy-load-bg full-width zi" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/TcBuster-1400x1400-2.png" alt="TcBuster Non-viral Gene Editing for Immune Cell Therapy"> </a> </div> </div> </div> <div class="columns small-12 medium-6 content color-white "> <h2 class="title color-navy-blue mb-40">Gene editing without the viral vector baggage.</h2> <div class="text last-no-margin"></p> <div>TcBuster non-viral genetic delivery system and gene editing services solve the supply chain and timeline bottlenecks facing viral vector-based editing while maintaining high insertion efficiency and a low-risk profile. Proven to insert CAR and TCR constructs reliably and cost-effectively into T cells and NK cells, TcBuster is the future of genetically engineered autologous and allogeneic cell therapies. ScaleReady offers gene editing services in partnership with Bio-Techne.</div> <p> </div> <a class="button mb-0" href="https://www.scaleready.com/product/tcbuster-non-viral-gene-engineering-system/#tcbuster_form" target=""> Talk to an Expert </a> </div> </div> <div class="row"> <div class="columns small-12 medium-12"> </div> </div> <script type="text/javascript"> jQuery('.fifty-fifty-content-calendar').parents('.section-50-wrapper').addClass('zIndex-3'); </script> </div> </div> </div> </div></div></div></div><div class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="sr_full_width_content section-50-wrapper st-lazy-load-bg bg-cover" data-src='https://www.scaleready.com/wp-content/uploads/2021/09/Group-239.png'> <div class="section-50-items position-relative zIndex-4"> <div class="small-collapse-section"> <div class="row align-middle section-50-item "> <div class="columns small-12 medium-6 small-order-1 medium-order-2 "> <div class="position-relative"> <div class="revealator-zoomin rev-item"></div> <div class="img-wrapper zi"> <a href="https://www.youtube.com/watch?v=bMVSnmxWARM" target=""> <img class="st-lazy-load-bg full-width zi" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/TcBuster-Video-graphic.png" alt="How does TcBuster Gene Editing Work"> </a> </div> </div> </div> <div class="columns small-12 medium-6 content color-black small-order-2 medium-order-1"> <h2 class="title color-navy-blue mb-40">How does TcBuster gene delivery work?</h2> <div class="text last-no-margin"><p>TcBuster integrates your gene of interest (GOI) into host cell DNA using the highly efficient Red Flour Beetle transposase and specifically-designed transposons. Transposon gene editing systems have the safest insertion profile of any commercial gene delivery platform, with limited off-target effects and stable, reliable gene expression.</p> </div> <a class="button mb-0" href="https://www.youtube.com/watch?v=bMVSnmxWARM" target=""> Watch Video </a> </div> </div> <div class="row"> <div class="columns small-12 medium-12"> </div> </div> <script type="text/javascript"> jQuery('.fifty-fifty-content-calendar').parents('.section-50-wrapper').addClass('zIndex-3'); </script> </div> </div> </div> <div class="sr_full_width_content section-50-wrapper st-lazy-load-bg bg-cover" data-src='https://www.scaleready.com/wp-content/uploads/2021/09/Group-411.jpg'> <div class="section-50-items position-relative zIndex-4"> <div class="small-collapse-section"> <div class="row align-middle section-50-item "> <div class="columns small-12 medium-6 "> <div class="position-relative"> <div class="revealator-zoomin rev-item"></div> <div class="img-wrapper zi"> <a href="https://www.scaleready.com/resource/tcbuster-non-viral-genetic-engineering-flyer/" target=""> <img class="st-lazy-load-bg full-width zi" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/Web-image-1400x1400-8.jpg" alt="CAR-T gene editing using TcBuster transposition or Lentivirus transduction"> </a> </div> </div> </div> <div class="columns small-12 medium-6 content color-white "> <h2 class="title color-navy-blue mb-40">Insert large CAR payloads and maintain high efficiency.</h2> <div class="text last-no-margin"><p>TcBuster is advancing TCR and CAR-T engineering by accommodating insertion of large and multi-gene constructs. This allows you to create innovative, highly targeted, and controlled gene-modified immune cell therapies. Using optimized protocols, TcBuster transposition efficiency even outperforms lentivirus transduction.</p> </div> <a class="button mb-0" href="https://www.scaleready.com/resource/tcbuster-non-viral-genetic-engineering-flyer/" target=""> Learn More... </a> </div> </div> <div class="row"> <div class="columns small-12 medium-12"> </div> </div> <script type="text/javascript"> jQuery('.fifty-fifty-content-calendar').parents('.section-50-wrapper').addClass('zIndex-3'); </script> </div> </div> </div> </div></div></div></div><div class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="sr_full_width_content section-50-wrapper st-lazy-load-bg bg-cover" data-src='https://www.scaleready.com/wp-content/uploads/2021/08/Group-424.png'> <div class="corner-image bottom-left"> <img decoding="async" src="https://www.scaleready.com/wp-content/uploads/2021/09/figure-molecule.png" alt="figure-molecule"> </div> <div class="section-50-items position-relative zIndex-4"> <div class="small-collapse-section"> <div class="row align-middle section-50-item "> <div class="columns small-12 medium-6 small-order-1 medium-order-2 "> <div class="position-relative"> <div class="revealator-zoomin rev-item"></div> <div class="img-wrapper zi"> <img class="st-lazy-load-bg full-width zi" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/Web-image-1400x1400-10.jpg" alt="TcBuster transposon gene editing comparison to Lentivirus transduction"> </div> </div> </div> <div class="columns small-12 medium-6 content color-black small-order-2 medium-order-1"> <h2 class="title color-navy-blue mb-40">CAR and TCR gene transfer without the viral vector baggage.</h2> <div class="text last-no-margin"><p>TcBuster addresses the cost, scalability, and integration challenges of retroviral and lentiviral vectors, as demonstrated in the table below. Manufacturing of TcBuster plasmids is inherently faster and less variable than retro and lentiviral production creating a more secure supply chain to support your gene edited immune cell therapies.</p> <p> </p> <p><a href="https://live-scaleready.pantheonsite.io/resource/tcbuster-non-viral-genetic-engineering-flyer/" target="_blank" rel="noopener"><span style="color: #31c8d8;"><strong>> Learn More</strong></span></a></p> </div> </div> </div> <div class="row"> <div class="columns small-12 medium-12"> </div> </div> <script type="text/javascript"> jQuery('.fifty-fifty-content-calendar').parents('.section-50-wrapper').addClass('zIndex-3'); </script> </div> </div> </div> <div class="sr_full_width_content section-50-wrapper st-lazy-load-bg bg-cover" data-src='https://www.scaleready.com/wp-content/uploads/2021/08/Group-268-min.png'> <div class="corner-image bottom-left"> <img decoding="async" src="https://www.scaleready.com/wp-content/uploads/2021/09/figure-molecule.png" alt="figure-molecule"> </div> <div class="section-50-items position-relative zIndex-4"> <div class="small-collapse-section"> <div class="row align-middle section-50-item "> <div class="columns small-12 medium-6 "> <div class="position-relative"> <div class="revealator-zoomin rev-item"></div> <div class="img-wrapper zi"> <img class="st-lazy-load-bg full-width zi" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/Web-image-500x500-9.jpg" alt="G-Rex expansion of CAR-T Cells following TcBuster transposon gene editing."> </div> </div> </div> <div class="columns small-12 medium-6 content color-white "> <h2 class="title color-navy-blue mb-40">Scalable gene editing to support cell therapy manufacturing.</h2> <div class="text last-no-margin"><p>TcBuster gene edited immune cells are compatible with cell expansion in closed-system <a href="https://live-scaleready.pantheonsite.io/product/g-rex/">G-Rex bioreactors</a>. Optimized transposition and expansion protocols will support research and therapeutic scales.</p> <p><a href="https://live-scaleready.pantheonsite.io/resource/g-rex-revolutionizing-cell-therapy-manufacturing-2/" target="_blank" rel="noopener"><span style="color: #31c8d8;"><strong>>Download the Brochure</strong></span></a></p> </div> </div> </div> <div class="row"> <div class="columns small-12 medium-12"> </div> </div> <script type="text/javascript"> jQuery('.fifty-fifty-content-calendar').parents('.section-50-wrapper').addClass('zIndex-3'); </script> </div> </div> </div> </div></div></div></div><div id="tcbuster_form" data-vc-full-width="true" data-vc-full-width-init="false" class="vc_row wpb_row vc_row-fluid bg-cover vc_custom_1696775321410 vc_row-has-fill"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"><div id="manufacturer_items" class="sr_full_width_content bg-cover st-lazy-load-bg p-bioreactor" > <div class="section-title-wrapper v-2 mb-40 position-relative zIndex-2"> <h2 class="title mb-40 smb-20 color-deep-blue">TcBuster gene editing service options</h2> <div class="intro-text"> From proof-of-concept studies and process optimization to GMP cell line manufacturing or technology licensing, we have you covered. We’ve partnered with Bio-Techne’s process development to make sure TcBuster integrates seamlessly into your clinical manufacturing process.</p> <p>Contact a gene-editing specialist at ScaleReady using the form below >> </div> </div> <div class="row position-relative zIndex-3 "> </div> <div> </div> </div> <div class='gf_browser_ie gf_browser_ie7 gform_wrapper gravity-theme gform-theme--no-framework form-align-center_wrapper' data-form-theme='gravity-theme' data-form-index='0' id='gform_wrapper_11' style='display:none'><div id='gf_11' class='gform_anchor' tabindex='-1'></div><form method='post' enctype='multipart/form-data' target='gform_ajax_frame_11' id='gform_11' class='form-align-center' action='/product/tcbuster-non-viral-gene-engineering-system-for-cell-and-gene-therapy/#gf_11' data-formid='11' novalidate> <div class='gform-body gform_body'><div id='gform_fields_11' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id="field_11_1" class="gfield gfield--type-text gfield--width-half gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible" data-js-reload="field_11_1" ><label class='gfield_label gform-field-label' for='input_11_1'>*First Name<span class="gfield_required"><span class="gfield_required gfield_required_text">(Required)</span></span></label><div class='ginput_container ginput_container_text'><input name='input_1' id='input_11_1' type='text' value='' class='large' aria-required="true" aria-invalid="false" /> </div></div><div id="field_11_2" class="gfield gfield--type-text gfield--width-half gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible" data-js-reload="field_11_2" ><label class='gfield_label gform-field-label' for='input_11_2'>*Last Name<span class="gfield_required"><span class="gfield_required gfield_required_text">(Required)</span></span></label><div class='ginput_container ginput_container_text'><input name='input_2' id='input_11_2' type='text' value='' class='large' aria-required="true" aria-invalid="false" /> </div></div><div id="field_11_3" class="gfield gfield--type-email gfield--width-half gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible" data-js-reload="field_11_3" ><label class='gfield_label gform-field-label' for='input_11_3'>*Email Address<span class="gfield_required"><span class="gfield_required gfield_required_text">(Required)</span></span></label><div class='ginput_container ginput_container_email'> <input name='input_3' id='input_11_3' type='email' value='' class='large' aria-required="true" aria-invalid="false" /> </div></div><div id="field_11_5" class="gfield gfield--type-text gfield--width-half gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible" data-js-reload="field_11_5" ><label class='gfield_label gform-field-label' for='input_11_5'>*Company<span class="gfield_required"><span class="gfield_required gfield_required_text">(Required)</span></span></label><div class='ginput_container ginput_container_text'><input name='input_5' id='input_11_5' type='text' value='' class='large' aria-required="true" aria-invalid="false" /> </div></div><div id="field_11_9" class="gfield gfield--type-select gfield--width-half gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible" data-js-reload="field_11_9" ><label class='gfield_label gform-field-label' for='input_11_9'>Country<span class="gfield_required"><span class="gfield_required gfield_required_text">(Required)</span></span></label><div class='ginput_container ginput_container_select'><select name='input_9' id='input_11_9' class='large gfield_select' aria-required="true" aria-invalid="false" ><option value='Afghanistan' >Afghanistan</option><option value='Albania' >Albania</option><option value='Algeria' >Algeria</option><option value='American Samoa' >American Samoa</option><option value='Andorra' >Andorra</option><option value='Angola' >Angola</option><option value='Anguilla' >Anguilla</option><option value='Antarctica' >Antarctica</option><option value='Antigua and Barbuda' >Antigua and Barbuda</option><option value='Argentina' >Argentina</option><option value='Armenia' >Armenia</option><option value='Aruba' >Aruba</option><option value='Australia' >Australia</option><option value='Austria' >Austria</option><option value='Azerbaijan' >Azerbaijan</option><option value='Bahamas' >Bahamas</option><option value='Bahrain' >Bahrain</option><option value='Bangladesh' >Bangladesh</option><option value='Barbados' >Barbados</option><option value='Belarus' >Belarus</option><option value='Belgium' >Belgium</option><option value='Belize' >Belize</option><option value='Benin' >Benin</option><option value='Bermuda' >Bermuda</option><option value='Bhutan' >Bhutan</option><option value='Bolivia' >Bolivia</option><option value='Bonaire, Sint Eustatius and Saba' >Bonaire, Sint Eustatius and Saba</option><option value='Bosnia and Herzegovina' >Bosnia and Herzegovina</option><option value='Botswana' >Botswana</option><option value='Bouvet Island' >Bouvet Island</option><option value='Brazil' >Brazil</option><option value='British Indian Ocean Territory' >British Indian Ocean Territory</option><option value='Brunei Darussalam' >Brunei Darussalam</option><option value='Bulgaria' >Bulgaria</option><option value='Burkina Faso' >Burkina Faso</option><option value='Burundi' >Burundi</option><option value='Cambodia' >Cambodia</option><option value='Cameroon' >Cameroon</option><option value='Canada' >Canada</option><option value='Cape Verde' >Cape Verde</option><option value='Cayman Islands' >Cayman Islands</option><option value='Central African Republic' >Central African Republic</option><option value='Chad' >Chad</option><option value='Chile' >Chile</option><option value='China' >China</option><option value='Christmas Island' >Christmas Island</option><option value='Cocos Islands' >Cocos Islands</option><option value='Colombia' >Colombia</option><option value='Comoros' >Comoros</option><option value='Congo, Democratic Republic of the' >Congo, Democratic Republic of the</option><option value='Congo, Republic of the' >Congo, Republic of the</option><option value='Cook Islands' >Cook Islands</option><option value='Costa Rica' >Costa Rica</option><option value='Croatia' >Croatia</option><option value='Cuba' >Cuba</option><option value='Curaçao' >Curaçao</option><option value='Cyprus' >Cyprus</option><option value='Czech Republic' >Czech Republic</option><option value='Côte d'Ivoire' >Côte d'Ivoire</option><option value='Denmark' >Denmark</option><option value='Djibouti' >Djibouti</option><option value='Dominica' >Dominica</option><option value='Dominican Republic' >Dominican Republic</option><option value='Ecuador' >Ecuador</option><option value='Egypt' >Egypt</option><option value='El Salvador' >El Salvador</option><option value='Equatorial Guinea' >Equatorial Guinea</option><option value='Eritrea' >Eritrea</option><option value='Estonia' >Estonia</option><option value='Eswatini (Swaziland)' >Eswatini (Swaziland)</option><option value='Ethiopia' >Ethiopia</option><option value='Falkland Islands' >Falkland Islands</option><option value='Faroe Islands' >Faroe Islands</option><option value='Fiji' >Fiji</option><option value='Finland' >Finland</option><option value='France' >France</option><option value='French Guiana' >French Guiana</option><option value='French Polynesia' >French Polynesia</option><option value='French Southern Territories' >French Southern Territories</option><option value='Gabon' >Gabon</option><option value='Gambia' >Gambia</option><option value='Georgia' >Georgia</option><option value='Germany' >Germany</option><option value='Ghana' >Ghana</option><option value='Gibraltar' >Gibraltar</option><option value='Greece' >Greece</option><option value='Greenland' >Greenland</option><option value='Grenada' >Grenada</option><option value='Guadeloupe' >Guadeloupe</option><option value='Guam' >Guam</option><option value='Guatemala' >Guatemala</option><option value='Guernsey' >Guernsey</option><option value='Guinea' >Guinea</option><option value='Guinea-Bissau' >Guinea-Bissau</option><option value='Guyana' >Guyana</option><option value='Haiti' >Haiti</option><option value='Heard and McDonald Islands' >Heard and McDonald Islands</option><option value='Holy See' >Holy See</option><option value='Honduras' >Honduras</option><option value='Hong Kong' >Hong Kong</option><option value='Hungary' >Hungary</option><option value='Iceland' >Iceland</option><option value='India' >India</option><option value='Indonesia' >Indonesia</option><option value='Iran' >Iran</option><option value='Iraq' >Iraq</option><option value='Ireland' >Ireland</option><option value='Isle of Man' >Isle of Man</option><option value='Israel' >Israel</option><option value='Italy' >Italy</option><option value='Jamaica' >Jamaica</option><option value='Japan' >Japan</option><option value='Jersey' >Jersey</option><option value='Jordan' >Jordan</option><option value='Kazakhstan' >Kazakhstan</option><option value='Kenya' >Kenya</option><option value='Kiribati' >Kiribati</option><option value='Kuwait' >Kuwait</option><option value='Kyrgyzstan' >Kyrgyzstan</option><option value='Lao People's Democratic Republic' >Lao People's Democratic Republic</option><option value='Latvia' >Latvia</option><option value='Lebanon' >Lebanon</option><option value='Lesotho' >Lesotho</option><option value='Liberia' >Liberia</option><option value='Libya' >Libya</option><option value='Liechtenstein' >Liechtenstein</option><option value='Lithuania' >Lithuania</option><option value='Luxembourg' >Luxembourg</option><option value='Macau' >Macau</option><option value='Macedonia' >Macedonia</option><option value='Madagascar' >Madagascar</option><option value='Malawi' >Malawi</option><option value='Malaysia' >Malaysia</option><option value='Maldives' >Maldives</option><option value='Mali' >Mali</option><option value='Malta' >Malta</option><option value='Marshall Islands' >Marshall Islands</option><option value='Martinique' >Martinique</option><option value='Mauritania' >Mauritania</option><option value='Mauritius' >Mauritius</option><option value='Mayotte' >Mayotte</option><option value='Mexico' >Mexico</option><option value='Micronesia' >Micronesia</option><option value='Moldova' >Moldova</option><option value='Monaco' >Monaco</option><option value='Mongolia' >Mongolia</option><option value='Montenegro' >Montenegro</option><option value='Montserrat' >Montserrat</option><option value='Morocco' >Morocco</option><option value='Mozambique' >Mozambique</option><option value='Myanmar' >Myanmar</option><option value='Namibia' >Namibia</option><option value='Nauru' >Nauru</option><option value='Nepal' >Nepal</option><option value='Netherlands' >Netherlands</option><option value='New Caledonia' >New Caledonia</option><option value='New Zealand' >New Zealand</option><option value='Nicaragua' >Nicaragua</option><option value='Niger' >Niger</option><option value='Nigeria' >Nigeria</option><option value='Niue' >Niue</option><option value='Norfolk Island' >Norfolk Island</option><option value='North Korea' >North Korea</option><option value='Northern Mariana Islands' >Northern Mariana Islands</option><option value='Norway' >Norway</option><option value='Oman' >Oman</option><option value='Pakistan' >Pakistan</option><option value='Palau' >Palau</option><option value='Palestine, State of' >Palestine, State of</option><option value='Panama' >Panama</option><option value='Papua New Guinea' >Papua New Guinea</option><option value='Paraguay' >Paraguay</option><option value='Peru' >Peru</option><option value='Philippines' >Philippines</option><option value='Pitcairn' >Pitcairn</option><option value='Poland' >Poland</option><option value='Portugal' >Portugal</option><option value='Puerto Rico' >Puerto Rico</option><option value='Qatar' >Qatar</option><option value='Romania' >Romania</option><option value='Russia' >Russia</option><option value='Rwanda' >Rwanda</option><option value='Réunion' >Réunion</option><option value='Saint Barthélemy' >Saint Barthélemy</option><option value='Saint Helena' >Saint Helena</option><option value='Saint Kitts and Nevis' >Saint Kitts and Nevis</option><option value='Saint Lucia' >Saint Lucia</option><option value='Saint Martin' >Saint Martin</option><option value='Saint Pierre and Miquelon' >Saint Pierre and Miquelon</option><option value='Saint Vincent and the Grenadines' >Saint Vincent and the Grenadines</option><option value='Samoa' >Samoa</option><option value='San Marino' >San Marino</option><option value='Sao Tome and Principe' >Sao Tome and Principe</option><option value='Saudi Arabia' >Saudi Arabia</option><option value='Senegal' >Senegal</option><option value='Serbia' >Serbia</option><option value='Seychelles' >Seychelles</option><option value='Sierra Leone' >Sierra Leone</option><option value='Singapore' >Singapore</option><option value='Sint Maarten' >Sint Maarten</option><option value='Slovakia' >Slovakia</option><option value='Slovenia' >Slovenia</option><option value='Solomon Islands' >Solomon Islands</option><option value='Somalia' >Somalia</option><option value='South Africa' >South Africa</option><option value='South Georgia' >South Georgia</option><option value='South Korea' >South Korea</option><option value='South Sudan' >South Sudan</option><option value='Spain' >Spain</option><option value='Sri Lanka' >Sri Lanka</option><option value='Sudan' >Sudan</option><option value='Suriname' >Suriname</option><option value='Svalbard and Jan Mayen Islands' >Svalbard and Jan Mayen Islands</option><option value='Sweden' >Sweden</option><option value='Switzerland' >Switzerland</option><option value='Syria' >Syria</option><option value='Taiwan' >Taiwan</option><option value='Tajikistan' >Tajikistan</option><option value='Tanzania' >Tanzania</option><option value='Thailand' >Thailand</option><option value='Timor-Leste' >Timor-Leste</option><option value='Togo' >Togo</option><option value='Tokelau' >Tokelau</option><option value='Tonga' >Tonga</option><option value='Trinidad and Tobago' >Trinidad and Tobago</option><option value='Tunisia' >Tunisia</option><option value='Turkey' >Turkey</option><option value='Turkmenistan' >Turkmenistan</option><option value='Turks and Caicos Islands' >Turks and Caicos Islands</option><option value='Tuvalu' >Tuvalu</option><option value='US Minor Outlying Islands' >US Minor Outlying Islands</option><option value='Uganda' >Uganda</option><option value='Ukraine' >Ukraine</option><option value='United Arab Emirates' >United Arab Emirates</option><option value='United Kingdom' >United Kingdom</option><option value='United States' selected='selected'>United States</option><option value='Uruguay' >Uruguay</option><option value='Uzbekistan' >Uzbekistan</option><option value='Vanuatu' >Vanuatu</option><option value='Venezuela' >Venezuela</option><option value='Vietnam' >Vietnam</option><option value='Virgin Islands, British' >Virgin Islands, British</option><option value='Virgin Islands, U.S.' >Virgin Islands, U.S.</option><option value='Wallis and Futuna' >Wallis and Futuna</option><option value='Western Sahara' >Western Sahara</option><option value='Yemen' >Yemen</option><option value='Zambia' >Zambia</option><option value='Zimbabwe' >Zimbabwe</option><option value='Åland Islands' >Åland Islands</option></select></div></div><div id="field_11_10" class="gfield gfield--type-select gfield--width-half gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible" data-js-reload="field_11_10" ><label class='gfield_label gform-field-label' for='input_11_10'>State<span class="gfield_required"><span class="gfield_required gfield_required_text">(Required)</span></span></label><div class='ginput_container ginput_container_select'><select name='input_10' id='input_11_10' class='large gfield_select' aria-required="true" aria-invalid="false" ><option value='Alabama' >Alabama</option><option value='Alaska' >Alaska</option><option value='Arizona' >Arizona</option><option value='Arkansas' >Arkansas</option><option value='California' >California</option><option value='Colorado' >Colorado</option><option value='Connecticut' >Connecticut</option><option value='Delaware' >Delaware</option><option value='District of Columbia' >District of Columbia</option><option value='Florida' >Florida</option><option value='Georgia' >Georgia</option><option value='Hawaii' >Hawaii</option><option value='Idaho' >Idaho</option><option value='Illinois' >Illinois</option><option value='Indiana' >Indiana</option><option value='Iowa' >Iowa</option><option value='Kansas' >Kansas</option><option value='Kentucky' >Kentucky</option><option value='Louisiana' >Louisiana</option><option value='Maine' >Maine</option><option value='Maryland' >Maryland</option><option value='Massachusetts' >Massachusetts</option><option value='Michigan' >Michigan</option><option value='Minnesota' >Minnesota</option><option value='Mississippi' >Mississippi</option><option value='Missouri' >Missouri</option><option value='Montana' >Montana</option><option value='Nebraska' >Nebraska</option><option value='Nevada' >Nevada</option><option value='New Hampshire' >New Hampshire</option><option value='New Jersey' >New Jersey</option><option value='New Mexico' >New Mexico</option><option value='New York' >New York</option><option value='North Carolina' >North Carolina</option><option value='North Dakota' >North Dakota</option><option value='Ohio' >Ohio</option><option value='Oklahoma' >Oklahoma</option><option value='Oregon' >Oregon</option><option value='Pennsylvania' >Pennsylvania</option><option value='Rhode Island' >Rhode Island</option><option value='South Carolina' >South Carolina</option><option value='South Dakota' >South Dakota</option><option value='Tennessee' >Tennessee</option><option value='Texas' >Texas</option><option value='Utah' >Utah</option><option value='Vermont' >Vermont</option><option value='Virginia' >Virginia</option><option value='Washington' >Washington</option><option value='West Virginia' >West Virginia</option><option value='Wisconsin' >Wisconsin</option><option value='Wyoming' >Wyoming</option></select></div></div><div id="field_11_12" class="gfield gfield--type-text gfield--width-full gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below 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class="text-18-24 mb-15 smb-40 text"> <div> TcBuster non-viral gene editing solves the bottlenecks facing viral vector-based editing, including supply chain, manufacturing time, and integration safety. 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