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value="Reset"></div> </div> <div class="resource-type-filter type-filter mb-50 position-relative"> <div class="small-filter text-24-29 ff-pnsb position-relative color-white show-for-small-only" id="show-filter"> All </div> <ul class="category-filters no-bullet mb-0"> <li class="category-filter filter-list "> <a class="text-24-29 display-block ff-pnsb" href="/knowledge-hq/" data-term-id="">All</a> </li> <li class="category-filter filter-list "> <a class="text-24-29 display-block ff-pnsb" href="/knowledge-hq/application-notes" data-term-id="application-notes">Application Notes</a> </li> <li class="category-filter filter-list "> <a class="text-24-29 display-block ff-pnsb" href="/knowledge-hq/case-studies" data-term-id="case-studies">Case Studies</a> </li> <li class="category-filter filter-list "> <a class="text-24-29 display-block ff-pnsb" href="/knowledge-hq/literature" data-term-id="literature">Literature</a> </li> <li class="category-filter filter-list "> <a class="text-24-29 display-block ff-pnsb" href="/knowledge-hq/protocols" data-term-id="protocols">Protocols</a> </li> <li class="category-filter filter-list "> <a class="text-24-29 display-block ff-pnsb" href="/knowledge-hq/scientific-posters" data-term-id="scientific-posters">Scientific Posters</a> </li> <li class="category-filter filter-list "> <a class="text-24-29 display-block ff-pnsb" href="/knowledge-hq/videos" data-term-id="videos">Videos</a> </li> <li class="category-filter filter-list "> <a class="text-24-29 display-block ff-pnsb" href="/knowledge-hq/webinar" data-term-id="webinar">Webinars</a> </li> <li><a class="text-24-29 display-block ff-pnsb" href="/insights">Insights</a></li> </ul> </div> </div> <div class="product-list-wrapper row"> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2023/07/CIMT-Poster-Featured-Image.png"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> Scientific Posters </div> <h2 class="h4 title color-navy-blue mb-25"> Development of large-scale expansion protocol for NKG2C-positive NK cells for treatment of glioblastoma </h2> <div class="text-18-24 mb-50"> This scientific poster presented at CIMT 2023 investigates glioblastoma, a WHO grade IV glioma and the most common primary adult brain tumor, and the expression of elevated levels of HLA-E that block NK cells with expression of the inhibitory NKG2A receptor, aiming to establish a large-scale ex vivo expansion of functional NKG2C+ NK cells. Doing so from peripheral blood employing bottom-gas permeable membrane bioreactors (G-Rex) and using a recently developed PC-3 feeder cell line genetically engineered with IL-2, membrane-bound IL-15, as well as a first generation single chain trimeric HLA-E molecule. </div> </div> <a target="_blank" class="button small mb-0" href="https://www.scaleready.com/resource/development-of-large-scale-expansion-protocol-for-nkg2c-positive-nk-cells-for-treatment-of-glioblastoma/">View Poster</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2023/04/SR-MKT-Webinar-Marker-FeaturedImage.png"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> Webinars </div> <h2 class="h4 title color-navy-blue mb-25"> Marker TX T-cell Manufacturing Simplification </h2> <div class="text-18-24 mb-50"> Join Anastasiya Smith, Snr. Director of R&D at Marker Therapeutics for a 15-minute pre-recorded webinar covering the first critical steps in successful automation through simplification with the G-Rex platform. </div> </div> <a class="button small mb-0" href="https://www.scaleready.com/knowledge-hq/webinars/marker-tx-t-cell-manufacturing-simplification/">View Webinar</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2023/04/SR-MKT-ProvenProcess-WebImage.png"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> Literature </div> <h2 class="h4 title color-navy-blue mb-25"> Proven Process </h2> <div class="text-18-24 mb-50"> This is our proven process illustrating how ScaleReady works in a true partnership with your T and NK cell therapy program to enable the successful commercialization of your drug. This is a linear left-to-right, as well as a holistic view, of how at every stage, we look to simplify, streamline, and scale by offering expertise and support for your cell therapy program. Through our proven process, we deliver practical and viable solutions by providing the most simple, scalable, and versatile manufacturing products. Our process is proven, as our products are represented in approved CAR-T drugs around the globe. </div> </div> <a target="_blank" class="button small mb-0" href="https://www.scaleready.com/resource/proven-process/">Download</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2023/01/SR-MKT-IL2Brochure-WebImage.png"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> Literature </div> <h2 class="h4 title color-navy-blue mb-25"> RUO and GMP IL-2 Cytokine Brochure </h2> <div class="text-18-24 mb-50"> GMP Recombinant Human IL-2 joins IL-7 and IL-15 produced within Bio-Techne’s dedicated animal-free GMP facility located in St. Paul MN USA. Our GMP-grade IL-2 contains the same cysteine to serine mutation found in Proleukin®. This mutation has been reported to prevent cysteine mispairing in E.coli, which can lead to protein aggregation and makes our new GMP-grade IL-2 protein soluble in injectable-grade water. </div> </div> <a target="_blank" class="button small mb-0" href="https://www.scaleready.com/resource/ruo-and-gmp-il-2-cytokine-brochure/">Download</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2023/01/SR-MKT-IL2715Brochure-WebImage.png"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> Literature </div> <h2 class="h4 title color-navy-blue mb-25"> IL-2, IL-7 and IL-15 Cytokines Brochure </h2> <div class="text-18-24 mb-50"> IL-2, IL-7, and IL-15 are critical cytokine components to many successful T and NK cell therapy programs. Choosing these cytokines from a partner that can offer seamless translation from RUO to GMP means that the consistency across lots, the confidence in bioactivity, and cost-effectiveness are no longer barriers to manufacturing with consistency, translating with speed and scaling without limitation. Learn more about these powerhouse cytokines in this brochure. </div> </div> <a target="_blank" class="button small mb-0" href="https://www.scaleready.com/resource/il-2-il-7-and-il-15-cytokines-brochure/">Download</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2022/12/SR-MKT-CueSpecSheet-Featured-Image.png"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> CUE, Literature </div> <h2 class="h4 title color-navy-blue mb-25"> Cue Product Specification Sheet </h2> <div class="text-18-24 mb-50"> Key features of the Cue Cell Processing System include flexibility - user-defined aliquot container number and fill volume, all-in-one - ability to concentrate and wash in the same procedure as final formulate and fill, precision - aliquot volumes ≤10 mL, and control - optional automated temperature control and mixing. </div> </div> <a target="_blank" class="button small mb-0" href="https://www.scaleready.com/resource/cue-product-specification-sheet/">Download</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2022/12/SR-MKT-Lovo-Brochure-Featured-Image.png"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> Literature, LOVO </div> <h2 class="h4 title color-navy-blue mb-25"> Lovo Large Volume Cell Processing System Brochure </h2> <div class="text-18-24 mb-50"> Whether you’re focused on early-stage trials or ramping up to full commercialization, Lovo’s spinning membrane filtration technology enables fast, precise, and flexible procedures that help increase your lab’s overall operational efficiency and processing consistency without compromising product quality. </div> </div> <a target="_blank" class="button small mb-0" href="https://www.scaleready.com/resource/lovo-large-volume-cell-processing-system-brochure/">Download</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2022/12/SR-MKT-TcBusterFAQ-WebFeaturedImage.png"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> Literature </div> <h2 class="h4 title color-navy-blue mb-25"> TcBuster Non-Viral Gene Engineering FAQ </h2> <div class="text-18-24 mb-50"> <span class="JsGRdQ">The benefits of non-viral gene engineering, when compared with its viral counterpart, offer simplicity, and streamlined capabilities all while lowering risk and cost.</span> <span class="JsGRdQ">TcBuster as part of the ScaleReady portfolio empowers cell therapy programs to move to market faster and with superior scalability ensuring confidence in reproducibility, bench to bedside. </span> </div> </div> <a target="_blank" class="button small mb-0" href="https://www.scaleready.com/resource/tcbuster-non-viral-gene-engineering-faq/">Download</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2022/11/cytokine-supplier-web-image.png"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> Literature </div> <h2 class="h4 title color-navy-blue mb-25"> Key Considerations for Choosing a Cytokine Supplier </h2> <div class="text-18-24 mb-50"> <span class="JsGRdQ">Within cell therapy manufacturing, GMP ancillary materials like cytokines are used as essential cell culture supplements to produce cell-based medicines. The success of the cell therapy will depend on the quality and consistency of these ancillary materials, making the choice of supplier a crucial decision to get right.</span> </div> </div> <a target="_blank" class="button small mb-0" href="https://www.scaleready.com/resource/key-considerations-for-choosing-a-cytokine-supplier/">Download</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2022/08/Lovo-Cue-Field-Service-and-Support-Web-Thumbnail-.png"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> CUE, Literature, LOVO </div> <h2 class="h4 title color-navy-blue mb-25"> Lovo and Cue Field Service and Support Flyer </h2> <div class="text-18-24 mb-50"> The rapid response and deployment of our Field Service and Support team are crucial to your process. This flyer is for Lovo and Cue customers who are looking to ensure that you have the support you need when you need it through Fresenius Kabi technical and customer service channels. </div> </div> <a target="_blank" class="button small mb-0" href="https://www.scaleready.com/resource/lovo-and-cue-field-service-and-support-flyer/">Download</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/Resource-web-thumbnails-webinar.png"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> CUE, Videos </div> <h2 class="h4 title color-navy-blue mb-25"> Cue Cell Processing System Spinning Membrane - Technical Video </h2> <div class="text-18-24 mb-50"> This technical video describes how Cue Cell Processing System combines its innovative spinning membrane technology with unique fluid dynamics to provide automated, closed-system small volume cell processing with unmatched precision. Cue enables high accuracy concentration, formulation, and aliquoting for cell therapy manufacturing. Applications include cryopreservation preparation, electroporation preparation, and fill/finish. </div> </div> <a target="_blank" class="button small mb-0" href="https://player.vimeo.com/video/912377813?h=61b93359ab">Watch Video</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-100 smb-40 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-white border-radius-32 box-shadow-20 overflow-hidden full-height p-card su"> <div class="bg-deep-blue"> <div class="revealator-fade responsive-embed normal bg-cover st-lazy-load-bg mb-0" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/Resource-web-thumbnails-webinar.png"> </div> </div> <div class="card-content matchHeight flex-container flex-dir-column"> <div class="flex-1"> <div class="eyebrow text-18-24 color-light-blue ff-pnsb text-uppercase mb-20 smb-10"> LOVO, Videos </div> <h2 class="h4 title color-navy-blue mb-25"> Lovo's Spinning Membrane - Technical Video </h2> <div class="text-18-24 mb-50"> This technical video describes how Lovo Cell Processing System uses its innovative spinning membrane technology to delivers automated, functionally closed processing for cell therapy manufacturing. Lovo's spinning membrane, combined with software that enables flexible input volumes and cell concentration outputs, is used for various closed-system cell processing applications, including leukapheresis wash, immunomagnetic separation preparation, cultured cell concentration, and thawed product DMSO removal. </div> </div> <a target="_blank" class="button small mb-0" href=" https://vimeo.com/953291221/0be19272a7?share=copy">Watch Video</a> </div> </div> </div> </div> <div class="row align-center ptb-80 padding-top-0"> <div class="columns shrink pagination color-white flex-container"> <a aria-label="Next Previous" class="prev page-numbers" href="https://www.scaleready.com/knowledge-hq/page/2/"></a> <a aria-label="Next Previous" class="page-numbers" href="https://www.scaleready.com/knowledge-hq/page/1/">1</a> <a aria-label="Next Previous" class="page-numbers" href="https://www.scaleready.com/knowledge-hq/page/2/">2</a> <span aria-current="page" class="page-numbers current">3</span> <a aria-label="Next Previous" class="page-numbers" href="https://www.scaleready.com/knowledge-hq/page/4/">4</a> <a aria-label="Next Previous" class="page-numbers" href="https://www.scaleready.com/knowledge-hq/page/5/">5</a> <a aria-label="Next Previous" class="next page-numbers" href="https://www.scaleready.com/knowledge-hq/page/4/"></a> </div> </div> </div> </div></div></div></div> </div> </div> </div> </div> </div> <div> </div> </article> </main> <footer class="footer color-white"> <div class="row position-relative zIndex-2"> <div class="columns small-12"> <section id="custom_html-2" class="widget_text widget widget_custom_html"><div class="textwidget custom-html-widget"><div class="row align-middle footer-top"> <div class="columns"> <div class="f-logo"> <img src="/wp-content/uploads/2021/08/Logo-White.png" alt="ScaleReady"> </div> </div> <div class="columns shrink flex-container"> <div class="ff-barlow fw-500 text"> <div class="fw-700">General Inquiries:</div> <a href="mailto:info@scaleready.com">info@scaleready.com</a> </div> <div class="ff-barlow fw-500 text"> <div class="fw-700">Career Opportunities:</div> <a href="mailto:careers@scaleready.com">careers@scaleready.com</a> </div> </div> </div> <hr /></div></section><section id="custom_html-3" class="widget_text widget widget_custom_html"><div class="textwidget custom-html-widget"><div class="row align-middle footer-middle"> <div class="columns"> <a class="f-social" href="https://www.linkedin.com/company/wearescaleready" title="Visit ScaleReady on LinkedIn" target="_blank" rel="noopener"> <img src="/wp-content/uploads/2021/08/Linkedin-Logo.png" alt="LinkedIn"> </a> </div> <div class="columns shrink flex-container"> <div class="ff-barlow fw-700 text"><a href="/terms-of-use">Terms of Use</a></div> <div class="ff-barlow fw-700 text"><a href="/privacy-policy">Privacy Policy</a></div> </div> </div></div></section><section id="text-2" class="widget widget_text"> <div class="textwidget"><div class="text-18-24 copyright">© 2024 ScaleReady USA</div> </div> </section> </div> </div> </footer> </div>  <script type='text/javascript'> piAId = '976203'; piCId = ''; piHostname = 'go.scaleready.com'; (function() { function async_load(){ var s = document.createElement('script'); s.type = 'text/javascript'; s.src = ('https:' == document.location.protocol ? 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