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T pomoćne 17 ćelije – Wikipedija/Википедија
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id="toc-Reference" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Reference"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Reference</span> </div> </a> <ul id="toc-Reference-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Literatura" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Literatura"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Literatura</span> </div> </a> <ul id="toc-Literatura-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Sadržaj" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" lang="sh-Latn" dir="ltr"> <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Prikaži/sakrij sadržaj" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Prikaži/sakrij sadržaj</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading" lang="sh-Latn" dir="ltr"><span class="mw-page-title-main">T pomoćne 17 ćelije</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" lang="sh-Latn" dir="ltr"> <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Prijedi na druge jezične varijante članka. Dostupno je na 15 jezika" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-15" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">15 jezika</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%AE%D9%84%D8%A7%D9%8A%D8%A7_%D8%AA%D9%8A_%D8%A7%D9%84%D9%85%D8%B3%D8%A7%D8%B9%D8%AF%D8%A9_Th17" title="خلايا تي المساعدة Th17 — Arapski" lang="ar" hreflang="ar" data-title="خلايا تي المساعدة Th17" data-language-autonym="العربية" data-language-local-name="Arapski" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Limf%C3%B2cit_Th17" title="Limfòcit Th17 — Katalonski" lang="ca" hreflang="ca" data-title="Limfòcit Th17" data-language-autonym="Català" data-language-local-name="Katalonski" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Th17_lymfocyt" title="Th17 lymfocyt — Češki" lang="cs" hreflang="cs" data-title="Th17 lymfocyt" data-language-autonym="Čeština" data-language-local-name="Češki" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/TH17-Zelle" title="TH17-Zelle — Nemački" lang="de" hreflang="de" data-title="TH17-Zelle" data-language-autonym="Deutsch" data-language-local-name="Nemački" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/T_helper_17_cell" title="T helper 17 cell — Engleski" lang="en" hreflang="en" data-title="T helper 17 cell" data-language-autonym="English" data-language-local-name="Engleski" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Th17" title="Th17 — Španski" lang="es" hreflang="es" data-title="Th17" data-language-autonym="Español" data-language-local-name="Španski" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%B3%D9%84%D9%88%D9%84_%DB%B1%DB%B7_%D8%AA%DB%8C_%DA%A9%D9%85%DA%A9%DB%8C" title="سلول ۱۷ تی کمکی — Persijski" lang="fa" hreflang="fa" data-title="سلول ۱۷ تی کمکی" data-language-autonym="فارسی" data-language-local-name="Persijski" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Lymphocyte_Th17" title="Lymphocyte Th17 — Francuski" lang="fr" hreflang="fr" data-title="Lymphocyte Th17" data-language-autonym="Français" data-language-local-name="Francuski" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/Th17%E7%B4%B0%E8%83%9E" title="Th17細胞 — Japanski" lang="ja" hreflang="ja" data-title="Th17細胞" data-language-autonym="日本語" data-language-local-name="Japanski" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/Th17%EC%84%B8%ED%8F%AC" title="Th17세포 — Korejski" lang="ko" hreflang="ko" data-title="Th17세포" data-language-autonym="한국어" data-language-local-name="Korejski" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/C%C3%A9lula_Th17" title="Célula Th17 — Portugalski" lang="pt" hreflang="pt" data-title="Célula Th17" data-language-autonym="Português" data-language-local-name="Portugalski" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/T-%D1%85%D0%B5%D0%BB%D0%BF%D0%B5%D1%80%D1%8B_17" title="T-хелперы 17 — Ruski" lang="ru" hreflang="ru" data-title="T-хелперы 17" data-language-autonym="Русский" data-language-local-name="Ruski" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/T_pomo%C4%87ne_17_%C4%87elije" title="T pomoćne 17 ćelije — Srpski" lang="sr" hreflang="sr" data-title="T pomoćne 17 ćelije" data-language-autonym="Српски / srpski" data-language-local-name="Srpski" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/T_Yard%C4%B1mc%C4%B1_H%C3%BCcresi_17" title="T Yardımcı Hücresi 17 — Turski" lang="tr" hreflang="tr" data-title="T Yardımcı Hücresi 17" data-language-autonym="Türkçe" data-language-local-name="Turski" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%A2-%D1%85%D0%B5%D0%BB%D0%BF%D0%B5%D1%80_17" title="Т-хелпер 17 — Ukrajinski" lang="uk" hreflang="uk" data-title="Т-хелпер 17" data-language-autonym="Українська" data-language-local-name="Ukrajinski" class="interlanguage-link-target"><span>Українська</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q768227#sitelinks-wikipedia" title="Uredi međujezične poveznice" class="wbc-editpage">Uredi 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<div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">Alati</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">premjesti na bočnu traku</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">sakrij</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions emptyPortlet vector-has-collapsible-items" 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dir="ltr"><div id="mw-content-subtitle" lang="sh-Latn" dir="ltr"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="sh-Latn" dir="ltr"><p><b>T pomoćne 17 ćelije</b> (<b>T<sub>h</sub>17</b>) su nedavno otkrivena podgrupa <a href="/wiki/T_pomo%C4%87na_%C4%87elija" class="mw-redirect" title="T pomoćna ćelija">T pomoćnih ćelija</a> koje proizvode <a href="/wiki/Interleukin_17" title="Interleukin 17">interleukin 17</a> (IL-17). One se smatraju razvojno različitim od T<sub>h</sub>1 i T<sub>h</sub>2 ćelija. Za prekomerne količine ovih ćelija se misli da imaju presudnu ulogu u <a href="/wiki/Autoimune_bolesti" title="Autoimune bolesti">autoimunskim oboljenjima</a><sup id="cite_ref-Harrington2005_1-0" class="reference"><a href="#cite_note-Harrington2005-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> kao što je <a href="/wiki/Multipla_skleroza" title="Multipla skleroza">multipla skleroza</a> (za koja se ranije mislilo da su izazvana T<sub>h</sub>1 ćelijama), a takođe i <a href="/wiki/Psorijaza" title="Psorijaza">psorijaza</a>, autoimunski uveitis, juvenilni dijabetes, <a href="/wiki/Reumatoidni_artritis" title="Reumatoidni artritis">reumatoidni artritis</a>. </p><p>Za ove ćelije se misli da učestvuju u <a href="/wiki/Zapaljenje" class="mw-redirect" title="Zapaljenje">inflamaciji</a> i oštećenju tkiva u tim oboljenjima.<sup id="cite_ref-pmid17290272_3-0" class="reference"><a href="#cite_note-pmid17290272-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> T<sub>h</sub>17 ćelije mogu da prouzrokuju ozbiljna autoimunska oboljenja, međutim one isto tako imaju veoma važnu funkciju u antimikrobnoj imunosti na <a href="/wiki/Epitel" class="mw-redirect" title="Epitel">epitelnim</a> / <a href="/wiki/Sluzoko%C5%BEa" class="mw-redirect" title="Sluzokoža">mukoznim</a> barijerama. One proizvode <a href="/wiki/Citokin" title="Citokin">citokine</a> (kao što je <a href="/wiki/Interleukin_22" title="Interleukin 22">interleukin 22</a>) koji stimulišu epitelne ćelije da proizvode antimikrobne proteine da be se odstranile određene vrste mikroba (kao što je <i><a href="/w/index.php?title=Kandida&action=edit&redlink=1" class="new" title="Kandida (stranica ne postoji)">kandida</a></i> i <i><a href="/wiki/Stafilokoke" title="Stafilokoke">stafilokoke</a></i>). Iz tog razloga, ozbiljan nedostatak T<sub>h</sub>17 ćelija može da dovesti do podložnosti na <a href="/w/index.php?title=Oportunisti%C4%8Dke_infekcije&action=edit&redlink=1" class="new" title="Oportunističke infekcije (stranica ne postoji)">oportunističke infekcije</a>. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Diferencijacija">Diferencijacija</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=T_pomo%C4%87ne_17_%C4%87elije&veaction=edit&section=1" title="Uredi odjeljak Diferencijacija" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=T_pomo%C4%87ne_17_%C4%87elije&action=edit&section=1" title="Uredi kôd odjeljka Diferencijacija"><span>uredi kod</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Ostaje nejasno koja kombinacija <a href="/wiki/Citokin" title="Citokin">citokina</a> doprinosi T<sub>h</sub>17 formaciji. <a href="/w/index.php?title=Transformi%C5%A1u%C4%87i_faktor_rasta_beta&action=edit&redlink=1" class="new" title="Transformišući faktor rasta beta (stranica ne postoji)">Transformišući faktor rasta beta</a> (TGF-β), <a href="/wiki/Interleukin_6" title="Interleukin 6">interleukin 6</a> (IL-6), <a href="/wiki/Interleukin_21" title="Interleukin 21">interleukin 21</a> (IL-21) i <a href="/wiki/Interleukin_23" title="Interleukin 23">interleukin 23</a> (IL-23) su bili implicirani kod miševa i ljudi.<sup id="cite_ref-pmid18408735_4-0" class="reference"><a href="#cite_note-pmid18408735-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid18454151_5-0" class="reference"><a href="#cite_note-pmid18454151-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> Postoje nesuglasice po pitanju uloge TGF-β kod ljudi, i smatra se da interleukin 1β možda takođe učestvuje u procesu. Drugi proteini sa ulogom u njihovoj diferencijaciji su signal transducer i aktivator transkripcije 3 (<a href="/w/index.php?title=STAT3&action=edit&redlink=1" class="new" title="STAT3 (stranica ne postoji)">STAT3</a>) i <a href="/wiki/RAR-srodni_orfan_receptor" title="RAR-srodni orfan receptor">RAR-srodni orfan receptori</a> alfa (<a href="/wiki/RAR-srodni_orfan_receptor_alfa" title="RAR-srodni orfan receptor alfa">RORα</a>) i gama (<a href="/wiki/RAR-srodni_orfan_receptor_gama" title="RAR-srodni orfan receptor gama">RORγ</a>).<sup id="cite_ref-pmid18408735_4-1" class="reference"><a href="#cite_note-pmid18408735-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> Efektor citokini asocirani sa ovim ćelijskim tipom su IL-17, IL-21 i IL-22.<sup id="cite_ref-pmid18400188_6-0" class="reference"><a href="#cite_note-pmid18400188-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p><p>Aktivacija prekurzor T pomoćnih ćelija u prisustvu TGF-β i IL-6 se misli da dovodi do diferencijacije T<sub>h</sub>17 ćelija kod miševa. Izuzev citokinskog okruženja, nije dovoljno jasno da li se neki drugi elementi inicijalne aktivacije T<sub>h</sub>17 ćelija razlikuju od drugih T pomoćnih ćelija. Bilo je predloženo da IL-23 učestvuje u ekspanziji uspostavljenih T<sub>h</sub>17 populacija, mada ovaj citokin pojedinačno ne indukuje diferencijaciju naivnih T-ćelijskih prekurzora u ovaj ćelijski tip.<sup id="cite_ref-pmid16648838_7-0" class="reference"><a href="#cite_note-pmid16648838-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> Za IL-21 citokin koji je proizveden od stane T<sub>h</sub>17 ćelija, je bilo pokazano da inicira alternativni put aktivacije T<sub>h</sub>17 populacija.<sup id="cite_ref-Korn2007_8-0" class="reference"><a href="#cite_note-Korn2007-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> Kod ljudi, kombinacija TGF-β, <a href="/wiki/Interleukin_1" title="Interleukin 1">IL-1β</a> i IL-23 indukuje T<sub>h</sub>17 diferencijaciju iz naivnih T ćelija.<sup id="cite_ref-pmid18454151_5-1" class="reference"><a href="#cite_note-pmid18454151-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> <a href="/wiki/Interferon-gama" title="Interferon-gama">Interferon-gama</a> (IFNγ) i <a href="/wiki/Interleukin_4" title="Interleukin 4">IL-4</a> su glavni stimulatori T<sub>h</sub>1 i T<sub>h</sub>2 diferencijacije. Za njih je bilo pokazano da negativno regulišu T<sub>h</sub>17 diferencijaciju. </p> <div class="mw-heading mw-heading2"><h2 id="Funkcije">Funkcije</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=T_pomo%C4%87ne_17_%C4%87elije&veaction=edit&section=2" title="Uredi odjeljak Funkcije" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=T_pomo%C4%87ne_17_%C4%87elije&action=edit&section=2" title="Uredi kôd odjeljka Funkcije"><span>uredi kod</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Tokom inicijalne karakterizacije, T<sub>h</sub>17 ćelije su bile implicirane u autoimuna oboljenja. Prirodnija uloga T<sub>h</sub>17 ćelija je bila predložena u studijama koje su demonstrirale preferencijalnu indukciju <a href="/wiki/IL-17" class="mw-disambig" title="IL-17">IL-17</a> u slučajevima infekcija sa različitim bakterijskim i gljivičnim vrstama. T<sub>h</sub>17 ćelija primarno proizvode dva glavna člana IL-17 familije, <a href="/wiki/IL-17A" class="mw-redirect" title="IL-17A">IL-17A</a> i <a href="/w/index.php?title=IL-17F&action=edit&redlink=1" class="new" title="IL-17F (stranica ne postoji)">IL-17F</a>, koji učestvuju u regrutovanju, aktivaciji i migracije <a href="/wiki/Neutrofil" title="Neutrofil">neutrofila</a>. Te ćelije takođe izlučuju <a href="/wiki/IL-21" class="mw-disambig" title="IL-21">IL-21</a> i <a href="/wiki/IL-22" class="mw-disambig" title="IL-22">IL-22</a>. Nedavno je za polarizovane T<sub>h</sub>17 ćelije bilo pokazano da posreduju regresiju tumora kod miševa.<sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> Da li je visoko inflamatorna priroda Th17 ćelija dovoljna da izazove ili doprinese karcinogenezi, je otvoreno pitanje.<sup id="cite_ref-11" class="reference"><a href="#cite_note-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Reference">Reference</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=T_pomo%C4%87ne_17_%C4%87elije&veaction=edit&section=3" title="Uredi odjeljak Reference" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=T_pomo%C4%87ne_17_%C4%87elije&action=edit&section=3" title="Uredi kôd odjeljka Reference"><span>uredi kod</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r41556849">.mw-parser-output .reflist{font-size:90%;margin-bottom:0.5em;list-style-type:decimal}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist reflist-columns references-column-width reflist-columns-2"> <ol class="references"> <li id="cite_note-Harrington2005-1"><span class="mw-cite-backlink"><a href="#cite_ref-Harrington2005_1-0">↑</a></span> <span class="reference-text"><span class="citation Journal">Harrington LE, Hatton RD, Mangan PR, <i>et al.</i> (November 2005). „Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages”. <i>Nature Immunology</i> <b>6</b> (11): 1123–32. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1038%2Fni1254">10.1038/ni1254</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/16200070">16200070</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Interleukin+17-producing+CD4%2B+effector+T+cells+develop+via+a+lineage+distinct+from+the+T+helper+type+1+and+2+lineages&rft.jtitle=Nature+Immunology&rft.aulast=Harrington+LE%2C+Hatton+RD%2C+Mangan+PR%2C+%27%27et+al.%27%27&rft.au=Harrington+LE%2C+Hatton+RD%2C+Mangan+PR%2C+%27%27et+al.%27%27&rft.date=November+2005&rft.volume=6&rft.issue=11&rft.pages=1123%E2%80%9332&rft_id=info:doi/10.1038%2Fni1254&rft_id=info:pmid/16200070&rfr_id=info:sid/en.wikipedia.org:T_pomo%C4%87ne_17_%C4%87elije"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><a href="#cite_ref-2">↑</a></span> <span class="reference-text"><span class="citation Journal">Stockinger B, Veldhoen M (June 2007). „Differentiation and function of Th17 T cells”. <i>Current Opinion in Immunology</i> <b>19</b> (3): 281–6. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2Fj.coi.2007.04.005">10.1016/j.coi.2007.04.005</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/17433650">17433650</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Differentiation+and+function+of+Th17+T+cells&rft.jtitle=Current+Opinion+in+Immunology&rft.aulast=Stockinger+B%2C+Veldhoen+M&rft.au=Stockinger+B%2C+Veldhoen+M&rft.date=June+2007&rft.volume=19&rft.issue=3&rft.pages=281%E2%80%936&rft_id=info:doi/10.1016%2Fj.coi.2007.04.005&rft_id=info:pmid/17433650&rfr_id=info:sid/en.wikipedia.org:T_pomo%C4%87ne_17_%C4%87elije"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-pmid17290272-3"><span class="mw-cite-backlink"><a href="#cite_ref-pmid17290272_3-0">↑</a></span> <span class="reference-text"><span class="citation Journal">Steinman L (February 2007). „A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage”. <i>Nat. Med.</i> <b>13</b> (2): 139–45. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1038%2Fnm1551">10.1038/nm1551</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/17290272">17290272</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=A+brief+history+of+T%28H%2917%2C+the+first+major+revision+in+the+T%28H%291%2FT%28H%292+hypothesis+of+T+cell-mediated+tissue+damage&rft.jtitle=Nat.+Med.&rft.aulast=Steinman+L&rft.au=Steinman+L&rft.date=February+2007&rft.volume=13&rft.issue=2&rft.pages=139%E2%80%9345&rft_id=info:doi/10.1038%2Fnm1551&rft_id=info:pmid/17290272&rfr_id=info:sid/en.wikipedia.org:T_pomo%C4%87ne_17_%C4%87elije"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-pmid18408735-4"><span class="mw-cite-backlink">↑ <sup><a href="#cite_ref-pmid18408735_4-0">4,0</a></sup> <sup><a href="#cite_ref-pmid18408735_4-1">4,1</a></sup></span> <span class="reference-text"><span class="citation Journal">Dong C (May 2008). „TH17 cells in development: an updated view of their molecular identity and genetic programming”. <i>Nature Reviews Immunology</i> <b>8</b> (5): 337–48. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1038%2Fnri2295">10.1038/nri2295</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/18408735">18408735</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=TH17+cells+in+development%3A+an+updated+view+of+their+molecular+identity+and+genetic+programming&rft.jtitle=Nature+Reviews+Immunology&rft.aulast=Dong+C&rft.au=Dong+C&rft.date=May+2008&rft.volume=8&rft.issue=5&rft.pages=337%E2%80%9348&rft_id=info:doi/10.1038%2Fnri2295&rft_id=info:pmid/18408735&rfr_id=info:sid/en.wikipedia.org:T_pomo%C4%87ne_17_%C4%87elije"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-pmid18454151-5"><span class="mw-cite-backlink">↑ <sup><a href="#cite_ref-pmid18454151_5-0">5,0</a></sup> <sup><a href="#cite_ref-pmid18454151_5-1">5,1</a></sup></span> <span class="reference-text"><span class="citation Journal">Manel N, Unutmaz D, Littman DR (June 2008). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2597394/">„The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat”</a>. <i>Nature Immunology</i> <b>9</b> (6): 641–9. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1038%2Fni.1610">10.1038/ni.1610</a>. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2597394">2597394</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/18454151">18454151</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+differentiation+of+human+T%28H%29-17+cells+requires+transforming+growth+factor-beta+and+induction+of+the+nuclear+receptor+RORgammat&rft.jtitle=Nature+Immunology&rft.aulast=Manel+N%2C+Unutmaz+D%2C+Littman+DR&rft.au=Manel+N%2C+Unutmaz+D%2C+Littman+DR&rft.date=June+2008&rft.volume=9&rft.issue=6&rft.pages=641%E2%80%939&rft_id=info:doi/10.1038%2Fni.1610&rft_id=info:pmc/2597394&rft_id=info:pmid/18454151&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2597394%2F&rfr_id=info:sid/en.wikipedia.org:T_pomo%C4%87ne_17_%C4%87elije"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-pmid18400188-6"><span class="mw-cite-backlink"><a href="#cite_ref-pmid18400188_6-0">↑</a></span> <span class="reference-text"><span class="citation Journal">Ouyang W, Kolls JK, Zheng Y (April 2008). „The biological functions of T helper 17 cell effector cytokines in inflammation”. <i>Immunity</i> <b>28</b> (4): 454–67. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2Fj.immuni.2008.03.004">10.1016/j.immuni.2008.03.004</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/18400188">18400188</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+biological+functions+of+T+helper+17+cell+effector+cytokines+in+inflammation&rft.jtitle=Immunity&rft.aulast=Ouyang+W%2C+Kolls+JK%2C+Zheng+Y&rft.au=Ouyang+W%2C+Kolls+JK%2C+Zheng+Y&rft.date=April+2008&rft.volume=28&rft.issue=4&rft.pages=454%E2%80%9367&rft_id=info:doi/10.1016%2Fj.immuni.2008.03.004&rft_id=info:pmid/18400188&rfr_id=info:sid/en.wikipedia.org:T_pomo%C4%87ne_17_%C4%87elije"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-pmid16648838-7"><span class="mw-cite-backlink"><a href="#cite_ref-pmid16648838_7-0">↑</a></span> <span class="reference-text"><span class="citation Journal">Bettelli E, Carrier Y, Gao W, <i>et al.</i> (May 2006). „Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells”. <i>Nature</i> <b>441</b> (7090): 235–8. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1038%2Fnature04753">10.1038/nature04753</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/16648838">16648838</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Reciprocal+developmental+pathways+for+the+generation+of+pathogenic+effector+TH17+and+regulatory+T+cells&rft.jtitle=Nature&rft.aulast=Bettelli+E%2C+Carrier+Y%2C+Gao+W%2C+%27%27et+al.%27%27&rft.au=Bettelli+E%2C+Carrier+Y%2C+Gao+W%2C+%27%27et+al.%27%27&rft.date=May+2006&rft.volume=441&rft.issue=7090&rft.pages=235%E2%80%938&rft_id=info:doi/10.1038%2Fnature04753&rft_id=info:pmid/16648838&rfr_id=info:sid/en.wikipedia.org:T_pomo%C4%87ne_17_%C4%87elije"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-Korn2007-8"><span class="mw-cite-backlink"><a href="#cite_ref-Korn2007_8-0">↑</a></span> <span class="reference-text"><span class="citation Journal">Korn T, Bettelli E, Gao W, <i>et al.</i> (July 2007). „IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells”. <i>Nature</i> <b>448</b> (7152): 484–7. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1038%2Fnature05970">10.1038/nature05970</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/17581588">17581588</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=IL-21+initiates+an+alternative+pathway+to+induce+proinflammatory+T%28H%2917+cells&rft.jtitle=Nature&rft.aulast=Korn+T%2C+Bettelli+E%2C+Gao+W%2C+%27%27et+al.%27%27&rft.au=Korn+T%2C+Bettelli+E%2C+Gao+W%2C+%27%27et+al.%27%27&rft.date=July+2007&rft.volume=448&rft.issue=7152&rft.pages=484%E2%80%937&rft_id=info:doi/10.1038%2Fnature05970&rft_id=info:pmid/17581588&rfr_id=info:sid/en.wikipedia.org:T_pomo%C4%87ne_17_%C4%87elije"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-9"><span class="mw-cite-backlink"><a href="#cite_ref-9">↑</a></span> <span class="reference-text"><span class="citation Journal">Muranski P, Boni A, Antony PA, <i>et al.</i> (July 2008). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2442746/">„Tumor-specific Th17-polarized cells eradicate large established melanoma”</a>. <i>Blood</i> <b>112</b> (2): 362–73. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1182%2Fblood-2007-11-120998">10.1182/blood-2007-11-120998</a>. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2442746">2442746</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/18354038">18354038</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Tumor-specific+Th17-polarized+cells+eradicate+large+established+melanoma&rft.jtitle=Blood&rft.aulast=Muranski+P%2C+Boni+A%2C+Antony+PA%2C+%27%27et+al.%27%27&rft.au=Muranski+P%2C+Boni+A%2C+Antony+PA%2C+%27%27et+al.%27%27&rft.date=July+2008&rft.volume=112&rft.issue=2&rft.pages=362%E2%80%9373&rft_id=info:doi/10.1182%2Fblood-2007-11-120998&rft_id=info:pmc/2442746&rft_id=info:pmid/18354038&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2442746%2F&rfr_id=info:sid/en.wikipedia.org:T_pomo%C4%87ne_17_%C4%87elije"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-10"><span class="mw-cite-backlink"><a href="#cite_ref-10">↑</a></span> <span class="reference-text"><span class="citation Journal">Martin-Orozco N, Muranski P, Chung Y, <i>et al.</i> (November 2009). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2787786/">„T helper 17 cells promote cytotoxic T cell activation in tumor immunity”</a>. <i>Immunity</i> <b>31</b> (5): 787–98. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2Fj.immuni.2009.09.014">10.1016/j.immuni.2009.09.014</a>. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2787786">2787786</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/19879162">19879162</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=T+helper+17+cells+promote+cytotoxic+T+cell+activation+in+tumor+immunity&rft.jtitle=Immunity&rft.aulast=Martin-Orozco+N%2C+Muranski+P%2C+Chung+Y%2C+%27%27et+al.%27%27&rft.au=Martin-Orozco+N%2C+Muranski+P%2C+Chung+Y%2C+%27%27et+al.%27%27&rft.date=November+2009&rft.volume=31&rft.issue=5&rft.pages=787%E2%80%9398&rft_id=info:doi/10.1016%2Fj.immuni.2009.09.014&rft_id=info:pmc/2787786&rft_id=info:pmid/19879162&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2787786%2F&rfr_id=info:sid/en.wikipedia.org:T_pomo%C4%87ne_17_%C4%87elije"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-11"><span class="mw-cite-backlink"><a href="#cite_ref-11">↑</a></span> <span class="reference-text"><span class="citation Journal">Wu S, Rhee KJ, Albesiano E, <i>et al.</i> (September 2009). „A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses”. <i>Nature Medicine</i> <b>15</b> (9): 1016–22. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1038%2Fnm.2015">10.1038/nm.2015</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/19701202">19701202</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=A+human+colonic+commensal+promotes+colon+tumorigenesis+via+activation+of+T+helper+type+17+T+cell+responses&rft.jtitle=Nature+Medicine&rft.aulast=Wu+S%2C+Rhee+KJ%2C+Albesiano+E%2C+%27%27et+al.%27%27&rft.au=Wu+S%2C+Rhee+KJ%2C+Albesiano+E%2C+%27%27et+al.%27%27&rft.date=September+2009&rft.volume=15&rft.issue=9&rft.pages=1016%E2%80%9322&rft_id=info:doi/10.1038%2Fnm.2015&rft_id=info:pmid/19701202&rfr_id=info:sid/en.wikipedia.org:T_pomo%C4%87ne_17_%C4%87elije"><span style="display: none;"> </span></span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="Literatura">Literatura</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=T_pomo%C4%87ne_17_%C4%87elije&veaction=edit&section=4" title="Uredi odjeljak Literatura" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=T_pomo%C4%87ne_17_%C4%87elije&action=edit&section=4" title="Uredi kôd odjeljka Literatura"><span>uredi kod</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r41379810">.mw-parser-output .refbegin{font-size:90%;margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}</style><div class="refbegin refbegin-columns references-column-count references-column-count-2" style="column-count: 2;"> <ul><li><span class="citation Journal">Egwuagu (2007). „TH17 cells contribute to uveitis and scleritis and are inhibited by IL-27/STAT1 in the retina (3) Western Blot Analysis”. <i>Nature Protocols</i>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1038%2Fnprot.2007.382">10.1038/nprot.2007.382</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=TH17+cells+contribute+to+uveitis+and+scleritis+and+are+inhibited+by+IL-27%2FSTAT1+in+the+retina+%283%29+Western+Blot+Analysis&rft.jtitle=Nature+Protocols&rft.aulast=Egwuagu&rft.au=Egwuagu&rft.date=2007&rft_id=info:doi/10.1038%2Fnprot.2007.382&rfr_id=info:sid/en.wikipedia.org:T_pomo%C4%87ne_17_%C4%87elije"><span style="display: none;"> </span></span></li> <li><span class="citation Journal">Egwuagu (2007). „TH17 cells contribute to uveitis and scleritis and are inhibited by IL-27/STAT1 in the retina (4) Confocal microscopy”. <i>Nature Protocols</i>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1038%2Fnprot.2007.383">10.1038/nprot.2007.383</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=TH17+cells+contribute+to+uveitis+and+scleritis+and+are+inhibited+by+IL-27%2FSTAT1+in+the+retina+%284%29+Confocal+microscopy&rft.jtitle=Nature+Protocols&rft.aulast=Egwuagu&rft.au=Egwuagu&rft.date=2007&rft_id=info:doi/10.1038%2Fnprot.2007.383&rfr_id=info:sid/en.wikipedia.org:T_pomo%C4%87ne_17_%C4%87elije"><span style="display: none;"> </span></span></li> <li><span class="citation Journal">Egwuagu (2007). „TH17 cells contribute to uveitis and scleritis and are inhibited by IL-27/STAT1 in the retina (5) Chromatin immunoprecipitation”. <i>Nature Protocols</i>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1038%2Fnprot.2007.384">10.1038/nprot.2007.384</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=TH17+cells+contribute+to+uveitis+and+scleritis+and+are+inhibited+by+IL-27%2FSTAT1+in+the+retina+%285%29+Chromatin+immunoprecipitation&rft.jtitle=Nature+Protocols&rft.aulast=Egwuagu&rft.au=Egwuagu&rft.date=2007&rft_id=info:doi/10.1038%2Fnprot.2007.384&rfr_id=info:sid/en.wikipedia.org:T_pomo%C4%87ne_17_%C4%87elije"><span style="display: none;"> </span></span></li></ul> </div> <div style="clear:both;"></div> <div class="navbox-styles nomobile"><style data-mw-deduplicate="TemplateStyles:r41348688">.mw-parser-output .navbox{box-sizing:border-box;border:1px solid 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.navbar-brackets::before{margin-right:-0.125em;content:"[ "}.mw-parser-output .navbar-brackets::after{margin-left:-0.125em;content:" ]"}.mw-parser-output .navbar li{word-spacing:-0.125em}.mw-parser-output .navbar a>span,.mw-parser-output .navbar a>abbr{text-decoration:inherit}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 7em}.mw-parser-output .navbar-ct-mini{font-size:114%;margin:0 4em}</style><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-prikaži"><a href="/wiki/%C5%A0ablon:Imunski_sistem" title="Šablon:Imunski sistem"><abbr title="Pogledajte šablon" style=";background:#efefef;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">p</abbr></a></li><li class="nv-razgovor"><a href="/wiki/Razgovor_o_%C5%A1ablonu:Imunski_sistem" title="Razgovor o šablonu:Imunski sistem"><abbr title="Razgovarajte o šablonu" style=";background:#efefef;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">r</abbr></a></li><li class="nv-uredi"><a class="external text" href="https://sh.wikipedia.org/w/index.php?title=%C5%A0ablon:Imunski_sistem&action=edit"><abbr title="Uredite šablon" style=";background:#efefef;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">u</abbr></a></li></ul></div><div id="Imunski_sistem_/_Imunologija" style="font-size:114%;margin:0 4em"><a href="/wiki/Imunski_sistem" title="Imunski sistem">Imunski sistem</a> / <a href="/wiki/Imunologija" title="Imunologija">Imunologija</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: LightGreen">Sistemi</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Adaptivni_imunski_sistem" title="Adaptivni imunski sistem">Adaptivni</a> vs. <a href="/w/index.php?title=Uro%C4%91eni_imunski_sistem&action=edit&redlink=1" class="new" title="Urođeni imunski sistem (stranica ne postoji)">Urođeni</a> •  <a href="/w/index.php?title=Humoralna_imunost&action=edit&redlink=1" class="new" title="Humoralna imunost (stranica ne postoji)">Humoralna</a> vs. <a href="/w/index.php?title=%C4%86elijski-posredovanja_imunost&action=edit&redlink=1" class="new" title="Ćelijski-posredovanja imunost (stranica ne postoji)">Ćelijska</a> •  <a href="/w/index.php?title=Komplementni_sistem&action=edit&redlink=1" class="new" title="Komplementni sistem (stranica ne postoji)">Komplementni</a> (<a href="/wiki/Anafilatoksin" title="Anafilatoksin">Anafilatoksini</a>) •  <a href="/w/index.php?title=Unutra%C5%A1nja_imunost&action=edit&redlink=1" class="new" title="Unutrašnja imunost (stranica ne postoji)">Unutrašnja</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: LightGreen">Limfoidni</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th id="Antigeni" scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: LightGreen"><div style="padding:0em 0.75em;">Antigeni</div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Antigen" title="Antigen">Antigen</a> (<a href="/w/index.php?title=Superantigen&action=edit&redlink=1" class="new" title="Superantigen (stranica ne postoji)">Superantigen</a>, <a href="/wiki/Alergen" title="Alergen">Alergen</a>) •  <a href="/w/index.php?title=Hapten&action=edit&redlink=1" class="new" title="Hapten (stranica ne postoji)">Hapten</a><br /> <a href="/wiki/Epitop" title="Epitop">Epitop</a> (<a href="/w/index.php?title=Linearni_epitop&action=edit&redlink=1" class="new" title="Linearni epitop (stranica ne postoji)">Linearni</a>, <a href="/w/index.php?title=Konformacioni_epitop&action=edit&redlink=1" class="new" title="Konformacioni epitop (stranica ne postoji)">Konformacioni</a>) •  <a href="/w/index.php?title=Mimotop&action=edit&redlink=1" class="new" title="Mimotop (stranica ne postoji)">Mimotop</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: LightGreen"><div style="padding:0em 0.75em;">Antitela</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Antitelo" title="Antitelo">Antitelo</a> (<a href="/wiki/Monoklonalna_antitela" class="mw-redirect" title="Monoklonalna antitela">Monoklonalna antitela</a>, <a href="/w/index.php?title=Poliklonalna_antitela&action=edit&redlink=1" class="new" title="Poliklonalna antitela (stranica ne postoji)">Poliklonalna antitela</a>, <a href="/w/index.php?title=Autoantitelo&action=edit&redlink=1" class="new" title="Autoantitelo (stranica ne postoji)">Autoantitelo</a>) •  <a href="/w/index.php?title=Odgovor_poliklonalnih_B_%C4%87elija&action=edit&redlink=1" class="new" title="Odgovor poliklonalnih B ćelija (stranica ne postoji)">Odgovor poliklonalnih B ćelija</a> •  <a href="/w/index.php?title=Imunoglobulinski_alotip&action=edit&redlink=1" class="new" title="Imunoglobulinski alotip (stranica ne postoji)">Alotip</a> •  <a href="/w/index.php?title=Izotip_(imunologija)&action=edit&redlink=1" class="new" title="Izotip (imunologija) (stranica ne postoji)">Izotip</a> •  <a href="/w/index.php?title=Idiotip&action=edit&redlink=1" class="new" title="Idiotip (stranica ne postoji)">Idiotip</a><br /> <a href="/w/index.php?title=Imunski_kompleks&action=edit&redlink=1" class="new" title="Imunski kompleks (stranica ne postoji)">Imunski kompleks</a> • <a href="/w/index.php?title=Paratop&action=edit&redlink=1" class="new" title="Paratop (stranica ne postoji)">Paratop</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: LightGreen"><div style="padding:0em 0.75em;">Imunost vs.<br /> tolerancija</div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><i>akcija:</i> <a href="/w/index.php?title=Imunitet_(medicina)&action=edit&redlink=1" class="new" title="Imunitet (medicina) (stranica ne postoji)">Imunitet</a> •  <a href="/w/index.php?title=Autoimunitet&action=edit&redlink=1" class="new" title="Autoimunitet (stranica ne postoji)">Autoimunitet</a> •  <a href="/w/index.php?title=Aloimunitet&action=edit&redlink=1" class="new" title="Aloimunitet (stranica ne postoji)">Aloimunitet</a> •  <a href="/wiki/Alergija" title="Alergija">Alergija</a> •  <a href="/wiki/Hipersenzitivnost" title="Hipersenzitivnost">Hipersenzitivnost</a> •  <a href="/wiki/Zapaljenje" class="mw-redirect" title="Zapaljenje">Inflamacija</a> •  <a href="/w/index.php?title=Kros-reaktivnost&action=edit&redlink=1" class="new" title="Kros-reaktivnost (stranica ne postoji)">Kros-reaktivnost</a><br /><i>neaktivnost:</i> <a href="/wiki/Imunska_tolerancija" class="mw-redirect" title="Imunska tolerancija">Tolerancija</a> (<a href="/wiki/Centralna_tolerancija" title="Centralna tolerancija">Centralna</a>, <a href="/w/index.php?title=Periferna_tolerancija&action=edit&redlink=1" class="new" title="Periferna tolerancija (stranica ne postoji)">Periferna</a>, <a href="/w/index.php?title=Klonalna_anergija&action=edit&redlink=1" class="new" title="Klonalna anergija (stranica ne postoji)">Klonalna anergija</a>, <a href="/w/index.php?title=Klonalno_brisanje&action=edit&redlink=1" class="new" title="Klonalno brisanje (stranica ne postoji)">Klonalno brisanje</a>, <a href="/w/index.php?title=Imunka_tolerancija_u_trudno%C4%87i&action=edit&redlink=1" class="new" title="Imunka tolerancija u trudnoći (stranica ne postoji)">Tolerancija u trudnoći</a>) •  <a href="/wiki/Imunodeficijencija" title="Imunodeficijencija">Imunodeficijencija</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: LightGreen"><div style="padding:0em 0.75em;"><a href="/w/index.php?title=Imunogenetika&action=edit&redlink=1" class="new" title="Imunogenetika (stranica ne postoji)">Imunogenetika</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/w/index.php?title=Somatska_hipermutacija&action=edit&redlink=1" class="new" title="Somatska hipermutacija (stranica ne postoji)">Somatska hipermutacija</a> •  <a href="/wiki/V(D)J_rekombinacija" title="V(D)J rekombinacija">V(D)J rekombinacija</a> •  <a href="/w/index.php?title=Sastavna_raznovrsnost&action=edit&redlink=1" class="new" title="Sastavna raznovrsnost (stranica ne postoji)">Sastavna raznovrsnost</a>  •  <a href="/w/index.php?title=Promena_imunoglobulinske_klase&action=edit&redlink=1" class="new" title="Promena imunoglobulinske klase (stranica ne postoji)">Promena imunoglobulinske klase</a> •  <a href="/w/index.php?title=Glavni_histokompatibilni_kompleks&action=edit&redlink=1" class="new" title="Glavni histokompatibilni kompleks (stranica ne postoji)">MHC</a>/<a href="/w/index.php?title=Ljudski_leukocitni_antigen&action=edit&redlink=1" class="new" title="Ljudski leukocitni antigen (stranica ne postoji)">HLA</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: LightGreen">Imunske ćelije/<br /><a href="/wiki/Bela_krvna_zrnca" class="mw-redirect" title="Bela krvna zrnca">Bela krvna zrnca</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><b>Limfoid</b>: <a href="/w/index.php?title=T_%C4%87elija&action=edit&redlink=1" class="new" title="T ćelija (stranica ne postoji)">T ćelija</a> •  <a href="/w/index.php?title=B_%C4%87elija&action=edit&redlink=1" class="new" title="B ćelija (stranica ne postoji)">B ćelija</a> •  <a href="/wiki/%C4%86elije_ubice" title="Ćelije ubice">NK ćelija</a> <p><b>Mijeloid</b>: <a href="/wiki/Mast_%C4%87elija" class="mw-redirect" title="Mast ćelija">Mast ćelija</a> •  <a href="/w/index.php?title=Bazofil_granulocit&action=edit&redlink=1" class="new" title="Bazofil granulocit (stranica ne postoji)">Bazofil</a> •  <a href="/wiki/Eozinofil" title="Eozinofil">Eozinofil</a> •  <b><a href="/wiki/Fagocit" title="Fagocit">Fagociti</a></b> (<a href="/wiki/Neutrofil" title="Neutrofil">Neutrofil</a>, <a href="/wiki/Makrofag" title="Makrofag">Makrofag</a>/<a href="/w/index.php?title=Retikuloendotelni_sistem&action=edit&redlink=1" class="new" title="Retikuloendotelni sistem (stranica ne postoji)">Retikuloendotelni sistem</a>) </p> <b><a href="/w/index.php?title=Antigen-prezentiraju%C4%87e_%C4%87elije&action=edit&redlink=1" class="new" title="Antigen-prezentirajuće ćelije (stranica ne postoji)">APC</a></b>: <a href="/wiki/Dendritska_%C4%87elija" title="Dendritska ćelija">Dendritska ćelija</a> •  <a href="/wiki/Makrofag" title="Makrofag">Makrofag</a> •  <a href="/w/index.php?title=B_%C4%87elija&action=edit&redlink=1" class="new" title="B ćelija (stranica ne postoji)">B ćelija</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: LightGreen">Supstance</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Citokin" title="Citokin">Citokini</a> •  <a href="/wiki/Opsonin" title="Opsonin">Opsonin</a> •  <a href="/w/index.php?title=Citolizin&action=edit&redlink=1" class="new" title="Citolizin (stranica ne postoji)">Citolizin</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: LightGreen"><a href="/w/index.php?title=Limfopoeza&action=edit&redlink=1" class="new" title="Limfopoeza (stranica ne postoji)">Limfopoeza</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/w/index.php?title=Limfoblast&action=edit&redlink=1" class="new" title="Limfoblast (stranica ne postoji)">Limfoblast</a> •  <a href="/w/index.php?title=Prolimfocit&action=edit&redlink=1" class="new" title="Prolimfocit (stranica ne postoji)">Prolimfocit</a> •  <a href="/w/index.php?title=Timocit&action=edit&redlink=1" class="new" title="Timocit (stranica ne postoji)">Timocit</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: LightGreen">Drugi</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/w/index.php?title=Dijagnosti%C4%8Dka_imunologija&action=edit&redlink=1" class="new" title="Dijagnostička imunologija (stranica ne postoji)">Dijagnostička imunologija</a>  •  <a href="/w/index.php?title=Otpornost_na_biljne_bolesti&action=edit&redlink=1" class="new" title="Otpornost na biljne bolesti (stranica ne postoji)">Otpornost na biljne bolesti</a>  •  <a href="/w/index.php?title=Antimikrobni_odbrambeni_sistem_respiratorni_trakta&action=edit&redlink=1" class="new" title="Antimikrobni odbrambeni sistem respiratorni trakta (stranica ne postoji)">Antimikrobni odbrambeni sistem respiratorni trakta</a></div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background:LightGreen;"><div></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><td colspan="2" class="navbox-list navbox-even" style="width:100%;padding:0;background:transparent;color:inherit;"><div style="padding:0px;"><table cellspacing="0" class="navbox-columns-table" style="text-align:left;width:100%;"><tbody><tr style="vertical-align:top;"><td style="padding:0px;text-align:center;background:#efefef;;;text-align:center;background:LightGreen;;width:10em;"><div> <p><a href="/wiki/%C5%A0ablon:Medicina_navs-lat" title="Šablon:Medicina navs-lat">M</a>: <a href="/wiki/Limfociti" class="mw-redirect" title="Limfociti">LMC</a> </p> </div></td><td style="border-left:2px solid #fdfdfd;padding:0px;text-align:center;background:#efefef;;;text-align:center;background:white;;width:10em;"><div> <p><a href="/w/index.php?title=%C5%A0ablon:Limfociti-lat&action=edit&redlink=1" class="new" title="Šablon:Limfociti-lat (stranica ne postoji)">ćelije</a>/<a href="/wiki/%C5%A0ablon:Imunski_sistem-lat" title="Šablon:Imunski sistem-lat">fis</a>/<a href="/w/index.php?title=%C5%A0ablon:Autoantigeni-lat&action=edit&redlink=1" class="new" title="Šablon:Autoantigeni-lat (stranica ne postoji)">auag</a>/<a href="/w/index.php?title=%C5%A0ablon:Autoantitela-lat&action=edit&redlink=1" class="new" title="Šablon:Autoantitela-lat (stranica ne postoji)">auab</a> </p> </div></td><td style="border-left:2px solid #fdfdfd;padding:0px;text-align:center;background:#efefef;;;text-align:center;background:silver;;width:10em;"><div> <p><a href="/w/index.php?title=%C5%A0ablon:Limfoid_i_komplement_imunodeficit-lat&action=edit&redlink=1" class="new" title="Šablon:Limfoid i komplement imunodeficit-lat (stranica ne postoji)">imdf</a>/<a href="/w/index.php?title=%C5%A0ablon:Imunoproliferativni_imunoglobulinski_poreme%C4%87aji-lat&action=edit&redlink=1" class="new" title="Šablon:Imunoproliferativni imunoglobulinski poremećaji-lat (stranica ne postoji)">ipig</a>/<a href="/w/index.php?title=%C5%A0ablon:Hipersenzitivnost_i_autoimune_bolesti-lat&action=edit&redlink=1" class="new" title="Šablon:Hipersenzitivnost i autoimune bolesti-lat (stranica ne postoji)">hyps</a>/<a href="/w/index.php?title=%C5%A0ablon:Limfoidna_malignost-lat&action=edit&redlink=1" class="new" title="Šablon:Limfoidna malignost-lat (stranica ne postoji)">tumr</a> </p> </div></td><td style="border-left:2px solid #fdfdfd;padding:0px;text-align:center;background:#efefef;;;text-align:center;background:#ccf;;width:10em;"><div> <p><a href="/w/index.php?title=%C5%A0ablon:Hemi%C4%8Dne/limfati%C4%8Dne_precedure-lat&action=edit&redlink=1" class="new" title="Šablon:Hemične/limfatične precedure-lat (stranica ne postoji)">proc</a>, lek (<a href="/wiki/%C5%A0ablon:Imunostimulanti-lat" title="Šablon:Imunostimulanti-lat">L3</a>/<a href="/wiki/%C5%A0ablon:Imunosupresanti-lat" title="Šablon:Imunosupresanti-lat">4</a>) </p> </div></td></tr></tbody></table></div></td></tr></tbody></table><div></div></td></tr></tbody></table></div> <div class="navbox-styles nomobile"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r41348688"></div><div role="navigation" class="navbox" aria-labelledby="Ćelijska_komunikacija:_Citokini" style="padding:3px"><table class="nowraplinks mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background:#e7dcc3"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r41556979"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r41556873"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-prikaži"><a href="/wiki/%C5%A0ablon:Citokini-lat" title="Šablon:Citokini-lat"><abbr title="Pogledajte šablon" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">p</abbr></a></li><li class="nv-razgovor"><a href="/wiki/Razgovor_o_%C5%A1ablonu:Citokini-lat" title="Razgovor o šablonu:Citokini-lat"><abbr title="Razgovarajte o šablonu" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">r</abbr></a></li><li class="nv-uredi"><a class="external text" href="https://sh.wikipedia.org/w/index.php?title=%C5%A0ablon:Citokini-lat&action=edit"><abbr title="Uredite šablon" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">u</abbr></a></li></ul></div><div id="Ćelijska_komunikacija:_Citokini" style="font-size:114%;margin:0 4em"><a href="/wiki/%C4%86elijska_komunikacija" title="Ćelijska komunikacija">Ćelijska komunikacija</a>: <a href="/wiki/Citokini" class="mw-redirect" title="Citokini">Citokini</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Po familiji</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Interleukin" title="Interleukin">Interleukin</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/IL-1" class="mw-disambig" title="IL-1">IL-1</a> superfamilija</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_1" title="Interleukin 1">1</a> (<a href="/wiki/Antagonist_interleukin-1_receptora" title="Antagonist interleukin-1 receptora">1Ra</a>) •  <a href="/wiki/Interleukin_18" title="Interleukin 18">18</a> •  <a href="/wiki/Interleukin_33" title="Interleukin 33">33</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">poput <a href="/wiki/IL-6" class="mw-disambig" title="IL-6">IL-6</a>/<a href="/wiki/Glikoprotein_130" title="Glikoprotein 130">gp130</a> koristeći</div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_6" title="Interleukin 6">6</a>  •  <a href="/wiki/Interleukin_11" title="Interleukin 11">11</a> •  <a href="/wiki/Interleukin_27" title="Interleukin 27">27</a> •  <a href="/wiki/Interleukin_30" title="Interleukin 30">30</a> •  <a href="/wiki/Interleukin_31" title="Interleukin 31">31</a> (+ne IL <a href="/wiki/Onkostatin_M" title="Onkostatin M">Onkostatin M</a>, <a href="/wiki/Inhibitorni_faktor_leukemije" title="Inhibitorni faktor leukemije">Inhibitorni faktor leukemije</a>, <a href="/wiki/Cilijarni_neurotrofni_faktor" title="Cilijarni neurotrofni faktor">Cilijarni neurotrofni faktor</a>, <a href="/wiki/Kardiotrofin_1" title="Kardiotrofin 1">Kardiotrofin 1</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/IL-10" class="mw-disambig" title="IL-10">IL-10</a> familija</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_10" title="Interleukin 10">10</a> •  <a href="/wiki/Interleukin_19" title="Interleukin 19">19</a> •  <a href="/wiki/Interleukin_20" title="Interleukin 20">20</a> •  <a href="/wiki/Interleukin_22" title="Interleukin 22">22</a> •  <a href="/wiki/Interleukin_24" title="Interleukin 24">24</a> •  <a href="/wiki/Interleukin_26" title="Interleukin 26">26</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Interferon_tip_III" title="Interferon tip III">Interferon tip III</a></div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_28" title="Interleukin 28">28</a> •  <a href="/wiki/Interleukin_29" title="Interleukin 29">29</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Zajedni%C4%8Dki_gama_lanac" class="mw-redirect" title="Zajednički gama lanac">Zajednički γ-lanac</a> familija</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_2" title="Interleukin 2">2</a>/<a href="/wiki/Interleukin_15" title="Interleukin 15">15</a> •  <a href="/wiki/Interleukin_3" title="Interleukin 3">3</a> •  <a href="/wiki/Interleukin_4" title="Interleukin 4">4</a> •  <a href="/wiki/Interleukin_7" title="Interleukin 7">7</a> •  <a href="/wiki/Interleukin_9" title="Interleukin 9">9</a> •  <a href="/wiki/Interleukin_13" title="Interleukin 13">13</a> •  <a href="/wiki/Interleukin_21" title="Interleukin 21">21</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/IL-12" class="mw-disambig" title="IL-12">IL-12</a> familija</div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_12" title="Interleukin 12">12</a> (<a href="/wiki/Interleukin_12B" title="Interleukin 12B">B</a>) •  <a href="/wiki/Interleukin_23" title="Interleukin 23">23</a> •  <a href="/wiki/Interleukin_27" title="Interleukin 27">27</a> •  <a href="/wiki/Interleukin_35" title="Interleukin 35">35</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">Drugi</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_5" title="Interleukin 5">5</a> •  <a href="/wiki/Interleukin_8" title="Interleukin 8">8</a> •  <a href="/wiki/Interleukin_14" title="Interleukin 14">14</a> •  <a href="/wiki/Interleukin_16" title="Interleukin 16">16</a> •  <a href="/wiki/Interleukin_17" title="Interleukin 17">17</a>/<a href="/wiki/Interleukin_25" title="Interleukin 25">25</a> (<a href="/wiki/Interleukin_17A" title="Interleukin 17A">A</a>) •  <a href="/wiki/Interleukin_32" title="Interleukin 32">32</a>  •  <a href="/wiki/Interleukin_34" title="Interleukin 34">34</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Hemokini" class="mw-redirect" title="Hemokini">Hemokini</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">CCL</div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/CCL1" title="CCL1">1</a> •  <a href="/wiki/CCL2" title="CCL2">2</a> •  <a href="/wiki/Makrofagni_inflamatorni_protein" title="Makrofagni inflamatorni protein">3</a> •  <a href="/wiki/CCL4" title="CCL4">4</a> •  <a href="/wiki/CCL5" title="CCL5">5</a> •  <a href="/wiki/CCL6" title="CCL6">6</a> •  <a href="/wiki/CCL7" title="CCL7">7</a> •  <a href="/wiki/CCL8" title="CCL8">8</a> •  <a href="/wiki/CCL9" title="CCL9">9</a> •  <a href="/wiki/CCL9" title="CCL9">10</a> •  <a href="/wiki/CCL11" title="CCL11">11</a> •  <a href="/wiki/CCL12" title="CCL12">12</a> •  <a href="/wiki/CCL13" title="CCL13">13</a> •  <a href="/wiki/CCL14" title="CCL14">14</a> •  <a href="/wiki/CCL15" title="CCL15">15</a> •  <a href="/wiki/CCL16" title="CCL16">16</a> •  <a href="/wiki/CCL17" title="CCL17">17</a> •  <a href="/wiki/CCL18" title="CCL18">18</a> •  <a href="/wiki/CCL19" title="CCL19">19</a> •  <a href="/wiki/CCL20" title="CCL20">20</a> •  <a href="/wiki/CCL21" title="CCL21">21</a> •  <a href="/wiki/CCL22" title="CCL22">22</a> •  <a href="/wiki/CCL23" title="CCL23">23</a> •  <a href="/wiki/CCL24" title="CCL24">24</a> •  <a href="/wiki/CCL25" title="CCL25">25</a> •  <a href="/wiki/CCL26" title="CCL26">26</a> •  <a href="/wiki/CCL27" title="CCL27">27</a> •  <a href="/wiki/CCL28" title="CCL28">28</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">CXCL</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/CXCL1" title="CXCL1">1</a> •  <a href="/wiki/CXCL2" title="CXCL2">2</a> •  <a href="/wiki/CXCL3" title="CXCL3">3</a> •  <a href="/wiki/Trombocit_faktor_4" title="Trombocit faktor 4">4</a> •  <a href="/wiki/CXCL5" title="CXCL5">5</a> •  <a href="/wiki/CXCL6" title="CXCL6">6</a> •  <a href="/wiki/CXCL7" title="CXCL7">7</a> •  <a href="/wiki/Interleukin_8" title="Interleukin 8">8</a> •  <a href="/wiki/CXCL9" title="CXCL9">9</a> •  <a href="/wiki/CXCL10" title="CXCL10">10</a> •  <a href="/wiki/CXCL11" title="CXCL11">11</a> •  <a href="/wiki/CXCL12" title="CXCL12">12</a> •  <a href="/wiki/CXCL13" title="CXCL13">13</a> •  <a href="/wiki/CXCL14" title="CXCL14">14</a> •  <a href="/wiki/CXCL15" title="CXCL15">15</a> •  <a href="/wiki/CXCL16" title="CXCL16">16</a> •  <a href="/wiki/CXCL17" title="CXCL17">17</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">CX3CL</div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/CX3CL1" title="CX3CL1">1</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">XCL</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/XCL1" title="XCL1">1</a> •  <a href="/wiki/XCL2" title="XCL2">2</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Faktori_nekroze_tumora" title="Faktori nekroze tumora">TNF</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">Glavni</div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Faktor_nekroze_tumora-alfa" title="Faktor nekroze tumora-alfa">TNF-alfa</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">TNF (<a href="/wiki/Ligand_(biohemija)" title="Ligand (biohemija)">ligand</a>) superfamilija</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/4-1BB_ligand" title="4-1BB ligand">4-1BB ligand</a> •  <a href="/wiki/Faktor_aktivacije_B-%C4%87elija" title="Faktor aktivacije B-ćelija">Faktor aktivacije B-ćelija</a> •  <a href="/wiki/Fas_ligand" title="Fas ligand">FAS ligand</a> •  <a href="/wiki/Limfotoksin" title="Limfotoksin">Limfotoksin</a> •  <a href="/wiki/OX40L" title="OX40L">OX40L</a> •  <a href="/wiki/RANKL" title="RANKL">RANKL</a> •  <a href="/wiki/TRAIL" title="TRAIL">TRAIL</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Klaster_diferencijacije" title="Klaster diferencijacije">Klaster diferencijacije</a></div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/CD70" title="CD70">CD70</a> •  <a href="/wiki/CD153" title="CD153">CD153</a> •  <a href="/wiki/CD154" title="CD154">CD154</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Interferon" title="Interferon">Interferon</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Interferon_tip_I" title="Interferon tip I">I</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em">alfa ( <a href="/wiki/Pegilirani_interferon_alfa-2a" title="Pegilirani interferon alfa-2a">Pegilirani 2a</a>, <a href="/wiki/Pegilirani_interferon_alfa-2b" title="Pegilirani interferon alfa-2b">Pegilirani 2b</a>), beta (<a href="/wiki/Interferon_beta-1a" title="Interferon beta-1a">1a</a>, <a href="/wiki/Interferon_beta-1b" title="Interferon beta-1b">1b</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Interferon_tip_II" title="Interferon tip II">II</a></div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interferon-gama" title="Interferon-gama">Gama</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Interferon_tip_III" title="Interferon tip III">III</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_28" title="Interleukin 28">IL-28</a> •  <a href="/wiki/Interleukin_29" title="Interleukin 29">IL-29</a></div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Drugi</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Monokin" title="Monokin">Monokin</a> •  <a href="/wiki/Limfokin" title="Limfokin">Limfokin</a> (<a href="/wiki/Limfotoksin" title="Limfotoksin">Limfotoksin</a>, <a href="/wiki/Faktor_transfera" title="Faktor transfera">Faktor transfera</a>) •  <a href="/wiki/Faktor_rasta" title="Faktor rasta">Faktor rasta</a> •  <a href="/wiki/Hematopoeza" title="Hematopoeza">Hematopoeza</a> (<a href="/wiki/Faktor_stem_%C4%87elija" title="Faktor stem ćelija">Faktor stem ćelija</a>, <a href="/wiki/Faktor_stimulacije_kolonije" title="Faktor stimulacije kolonije">Faktor stimulacije kolonije</a>) •  <a href="/wiki/GPI_(gen)" title="GPI (gen)">Faktor autokrinog motiliteta</a> •  <a href="/wiki/Osteopontin" title="Osteopontin">Osteopontin</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Po funkciji</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><i><a href="/wiki/Proinflamatorni_citokin" title="Proinflamatorni citokin">proinflamatorni citokin</a></i> (<a href="/wiki/Interleukin_1" title="Interleukin 1">IL-1</a>, <a href="/wiki/Faktor_nekroze_tumora-alfa" title="Faktor nekroze tumora-alfa">TNF-alfa</a>) •  <a href="/wiki/T_pomo%C4%87ne_%C4%87elije" title="T pomoćne ćelije"><i>T<sub>h</sub>1</i></a> (<a href="/wiki/Interferon-gama" title="Interferon-gama">INF-gama</a> i <a href="/wiki/Faktor_nekroze_tumora-beta" class="mw-redirect" title="Faktor nekroze tumora-beta">TNF-beta</a>) •  <a href="/wiki/T_pomo%C4%87ne_%C4%87elije" title="T pomoćne ćelije"><i>T<sub>h</sub>2</i></a> (<a href="/wiki/Interleukin_4" title="Interleukin 4">IL-4</a>, <a href="/wiki/Interleukin_5" title="Interleukin 5">IL-5</a>, <a href="/wiki/Interleukin_6" title="Interleukin 6">IL-6</a>, <a href="/wiki/Interleukin_10" title="Interleukin 10">IL-10</a>, <a href="/wiki/Interleukin_13" title="Interleukin 13">IL-13</a>) •  <a class="mw-selflink selflink"><i>T<sub>h</sub>17</i></a> (<a href="/wiki/Interleukin_17" title="Interleukin 17">IL-17</a>,<a href="/wiki/Interleukin_22" title="Interleukin 22">IL-22</a>)</div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background-color: AntiqueWhite"><div><i><a href="/wiki/%C5%A0ablon:Biohemija_metanavs-lat" title="Šablon:Biohemija metanavs-lat">B</a> <a href="/wiki/%C5%A0ablon:Prenos_signala-lat" title="Šablon:Prenos signala-lat">trdu</a>: <a href="/w/index.php?title=%C5%A0ablon:Intercelularni_signalni_peptidi_i_proteini-lat&action=edit&redlink=1" class="new" title="Šablon:Intercelularni signalni peptidi i proteini-lat (stranica ne postoji)">peptidi</a> (<a href="/wiki/%C5%A0ablon:Neuropeptidi-lat" title="Šablon:Neuropeptidi-lat">nrpl</a>/<a href="/wiki/%C5%A0ablon:Faktori_rasta-lat" title="Šablon:Faktori rasta-lat">grfl</a>/<a href="/wiki/%C5%A0ablon:Citokini-lat" title="Šablon:Citokini-lat">cytl</a>/<a href="/wiki/%C5%A0ablon:Hormoni-lat" title="Šablon:Hormoni-lat">horl</a>), <a href="/w/index.php?title=%C5%A0ablon:Receptori_%C4%87elijske_povr%C5%A1ine-lat&action=edit&redlink=1" class="new" title="Šablon:Receptori ćelijske površine-lat (stranica ne postoji)">receptori</a> (<a href="/w/index.php?title=%C5%A0ablon:Ligand-kontrolisani_jonski_kanali-lat&action=edit&redlink=1" class="new" title="Šablon:Ligand-kontrolisani jonski kanali-lat (stranica ne postoji)">lgic</a>, <a href="/w/index.php?title=%C5%A0ablon:Enzim-vezani_receptori-lat&action=edit&redlink=1" class="new" title="Šablon:Enzim-vezani receptori-lat (stranica ne postoji)">enzr</a>, <a href="/wiki/%C5%A0ablon:G_protein_spregnuti_receptori-lat" title="Šablon:G protein spregnuti receptori-lat">gprc</a>, <a href="/wiki/%C5%A0ablon:Imunoglobulinska_superfamilija_imunskih_receptora-lat" title="Šablon:Imunoglobulinska superfamilija imunskih receptora-lat">igsr</a>, <a href="/w/index.php?title=%C5%A0ablon:Integrini-lat&action=edit&redlink=1" class="new" title="Šablon:Integrini-lat (stranica ne postoji)">intg</a>, <a href="/wiki/%C5%A0ablon:Neuropeptidni_receptori-lat" title="Šablon:Neuropeptidni receptori-lat">nrpr</a>/<a href="/wiki/%C5%A0ablon:Receptori_faktora_rasta-lat" title="Šablon:Receptori faktora rasta-lat">grfr</a>/<a href="/wiki/%C5%A0ablon:Citokinski_receptori-lat" class="mw-redirect" title="Šablon:Citokinski receptori-lat">cytr</a>), <a href="/w/index.php?title=%C5%A0ablon:Intracelularni_signalni_peptidi_i_proteini-lat&action=edit&redlink=1" class="new" title="Šablon:Intracelularni signalni peptidi i proteini-lat (stranica ne postoji)">itra</a> (<a href="/w/index.php?title=%C5%A0ablon:Adapterski_proteini-lat&action=edit&redlink=1" class="new" title="Šablon:Adapterski proteini-lat (stranica ne postoji)">adap</a>, <a href="/wiki/%C5%A0ablon:Regulatori_GTP-vezuju%C4%87ih_proteina-lat" title="Šablon:Regulatori GTP-vezujućih proteina-lat">gbpr</a>, <a href="/w/index.php?title=%C5%A0ablon:Aktivacija_MAP_kinaze-lat&action=edit&redlink=1" class="new" title="Šablon:Aktivacija MAP kinaze-lat (stranica ne postoji)">mapk</a>), <a href="/w/index.php?title=%C5%A0ablon:Kalcjiumska_signalizacija-lat&action=edit&redlink=1" class="new" title="Šablon:Kalcjiumska signalizacija-lat (stranica ne postoji)">calc</a>, <a href="/wiki/%C5%A0ablon:Lipidna_signalizacija-lat" title="Šablon:Lipidna signalizacija-lat">lipd</a>, signalni putevi (<a href="/w/index.php?title=%C5%A0ablon:Hedgehog_signalni_put-lat&action=edit&redlink=1" class="new" title="Šablon:Hedgehog signalni put-lat (stranica ne postoji)">hedp</a>, <a href="/w/index.php?title=%C5%A0ablon:Wnt_signalni_put-lat&action=edit&redlink=1" class="new" title="Šablon:Wnt signalni put-lat (stranica ne postoji)">wntp</a>, <a href="/w/index.php?title=%C5%A0ablon:TGF_beta_signalizacija-lat&action=edit&redlink=1" class="new" title="Šablon:TGF beta signalizacija-lat (stranica ne postoji)">tgfp</a>+<a href="/wiki/%C5%A0ablon:MAPK_ERK_signalni_put-lat" title="Šablon:MAPK ERK signalni put-lat">mapp</a>, <a href="/w/index.php?title=%C5%A0ablon:Notch_signalni_put-lat&action=edit&redlink=1" class="new" title="Šablon:Notch signalni put-lat (stranica ne postoji)">notp</a>, <a href="/w/index.php?title=%C5%A0ablon:JAK-STAT_signalni_put-lat&action=edit&redlink=1" class="new" title="Šablon:JAK-STAT signalni put-lat (stranica ne postoji)">jakp</a>, <a href="/wiki/%C5%A0ablon:Apoptozni_signalni_put-lat" title="Šablon:Apoptozni signalni put-lat">fsap</a>, <a href="/w/index.php?title=%C5%A0ablon:Hippo_signalni_put-lat&action=edit&redlink=1" class="new" title="Šablon:Hippo signalni put-lat (stranica ne postoji)">hipp</a>, <a href="/w/index.php?title=%C5%A0ablon:TLR_signalni_put-lat&action=edit&redlink=1" class="new" title="Šablon:TLR signalni put-lat (stranica ne postoji)">tlrp</a>)</i></div></td></tr></tbody></table></div> <!-- NewPP limit report Parsed by mw‐api‐int.codfw.main‐5fd4fc67fd‐mgcdg Cached time: 20241105060417 Cache expiry: 2592000 Reduced expiry: false Complications: [show‐toc] CPU time usage: 0.373 seconds Real time usage: 0.414 seconds Preprocessor visited node count: 14060/1000000 Post‐expand include size: 228857/2097152 bytes Template argument size: 39798/2097152 bytes Highest expansion depth: 20/100 Expensive parser function count: 0/500 Unstrip recursion depth: 0/20 Unstrip post‐expand size: 33020/5000000 bytes Lua 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