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Medicinal plants produce an array of secondary metabolites to protect themselves against pathogens and can be exploited as phytomedicines for humans. In view of the benefits of medicinal plants, 41 medicinal plants of ethnomedicinal importance, belonging to 33 plant families were collected from Solan and Shimla regions of Himachal Pradesh, India. The ethanolic extracts of different parts (flowers, leaves and barks) of these plants were tested for antimicrobial activity against Staphylococcus aureus, prokaryotic bacterial pathogen and Candida albicans, an eukaryotic fungal pathogen using agar well diffusion assays. Collectively, the medicinal plants exhibited 2 fold more antimicrobial activity against prokaryotic pathogen (S. aureus) as compared to the eukaryotic pathogen (C. albicans). For S. aureus, 40 medicinal plants and their different parts exhibited antimicrobial activity whereas for C. albicans only 21 medicinal plants showed antifungal actvity. Amongst all medicinal plants, Hypericum perforatum (flowers) extract showed highest antimicrobial activity against S. aureus with the zone of inhibition of 19 mm and found bactericidal. On the other hand, Cymbopogon citrate (leaf) extract showed highest antifungal activity of 10 mm and fungicidal effect. The extracts of H. perforatum, C. citrate and T. arjuna were strong antimicrobial against both pathogens. It is hypothesized that phytocompounds present in these three plants might be following the same mechanism of action causing death of S. aureus and C. albicans. These findings have an implication for the development of phytomedicines/ drugs with pathogen-specific effect.","publication_date":"2014,,","grobid_abstract_attachment_id":"73161058"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Comparative Analysis of Antibacterial and Antifungal Properties of Traditional Medicinal Plants of Shimla and Solan, Himachal Pradesh. Vipasha Sharma, Harsh Vardhan Sharma, Disha Mehta, Bhavna Chhabra, Deepika Thakur, Anuradha Sourirajan, *Kamal Dev","broadcastable":true,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [14058562]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container js-loswp-work-card"><div class="ds-work-card--cover"><div class="ds-work-cover--wrapper"><div class="ds-work-cover--container"><button class="ds-work-cover--clickable js-swp-download-button" data-signup-modal="{"location":"swp-splash-paper-cover","attachmentId":73161058,"attachmentType":"pdf"}"><img alt="First page of “Comparative Analysis of Antibacterial and Antifungal Properties of Traditional Medicinal Plants of Shimla and Solan, Himachal Pradesh. Vipasha Sharma, Harsh Vardhan Sharma, Disha Mehta, Bhavna Chhabra, Deepika Thakur, Anuradha Sourirajan, *Kamal Dev”" class="ds-work-cover--cover-thumbnail" src="https://0.academia-photos.com/attachment_thumbnails/73161058/mini_magick20211019-17168-nt4opc.png?1634659683" /><img alt="PDF Icon" class="ds-work-cover--file-icon" src="//a.academia-assets.com/assets/single_work_splash/adobe.icon-574afd46eb6b03a77a153a647fb47e30546f9215c0ee6a25df597a779717f9ef.svg" /><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Comparative Analysis of Antibacterial and Antifungal Properties of Traditional Medicinal Plants of Shimla and Solan, Himachal Pradesh. Vipasha Sharma, Harsh Vardhan Sharma, Disha Mehta, Bhavna Chhabra, Deepika Thakur, Anuradha Sourirajan, *Kamal Dev</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="14058562" href="https://independent.academia.edu/Vipashasharma2"><img alt="Profile image of Vipasha sharma" class="ds-work-card--author-avatar" src="//a.academia-assets.com/images/s65_no_pic.png" />Vipasha sharma</a></div><div class="ds-work-card--detail"><p class="ds-work-card--detail ds2-5-body-sm">2014</p><div class="ds-work-card--work-metadata"><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">visibility</span><p class="ds2-5-body-sm" id="work-metadata-view-count">…</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">description</span><p class="ds2-5-body-sm">9 pages</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">link</span><p class="ds2-5-body-sm">1 file</p></div></div><script>(async () => { const workId = 59039081; 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class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="8359022" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/8359022/ANTIMICROBIAL_ACTIVITY_OF_THREE_INDIAN_MEDICINAL_PLANTS_AN_IN_VITRO_STUDY">ANTIMICROBIAL ACTIVITY OF THREE INDIAN MEDICINAL PLANTS – AN IN VITRO STUDY</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="883054" href="https://velsuniv.academia.edu/VanithaVinoth">Vanitha Vinoth</a></div><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"ANTIMICROBIAL ACTIVITY OF THREE INDIAN MEDICINAL PLANTS – AN IN VITRO 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href="https://www.academia.edu/15540893/Evaluation_of_antimicrobial_potential_of_some_Indian_medicinal_plants_against_some_pathogenic_microbes">Evaluation of antimicrobial potential of some Indian medicinal plants against some pathogenic microbes</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="34774082" href="https://independent.academia.edu/YogeshkumarVaghasiya">Yogeshkumar Vaghasiya</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="34695412" href="https://sauuni.academia.edu/sumitraachanda">sumitraa chanda</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="10576484" href="https://saurashtrauniversity.academia.edu/MitalKaneria">Mital Kaneria</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2011</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Evaluation of antimicrobial potential of some Indian medicinal plants against some pathogenic microbes","attachmentId":43105894,"attachmentType":"pdf","work_url":"https://www.academia.edu/15540893/Evaluation_of_antimicrobial_potential_of_some_Indian_medicinal_plants_against_some_pathogenic_microbes","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/15540893/Evaluation_of_antimicrobial_potential_of_some_Indian_medicinal_plants_against_some_pathogenic_microbes"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="4187194" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/4187194/Antifungal_potential_of_Indian_medicinal_plants">Antifungal potential of Indian medicinal plants</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="5066238" href="https://mdurohtak.academia.edu/RajeshDabur">Rajesh Dabur</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Fitoterapia, 2004</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Antifungal potential of Indian medicinal plants","attachmentId":49992895,"attachmentType":"pdf","work_url":"https://www.academia.edu/4187194/Antifungal_potential_of_Indian_medicinal_plants","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/4187194/Antifungal_potential_of_Indian_medicinal_plants"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="38566617" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/38566617/AN_ANALYTICAL_STUDY_OF_ANTIFUNGAL_ACTIVITY_OF_CRUDE_EXTRACTS_AND_ACTIVE_CONSTITUENTS_OF_INDIAN_HERBAL_PLANTS">AN ANALYTICAL STUDY OF ANTIFUNGAL ACTIVITY OF CRUDE EXTRACTS AND ACTIVE CONSTITUENTS OF INDIAN HERBAL PLANTS</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33085910" href="https://kuk.academia.edu/internationaljournal">Journal ijmr.net.in(UGC Approved)</a></div><p class="ds-related-work--abstract ds2-5-body-sm">In the light of late issues of numerous drug resistance and intractable microbial diseases, the need to discover new substances with antimicrobial properties winds up plainly correlated. The present work encompasses the screening of aqueous and methanol/ethanol extracts of 108 plant species randomly collected, for their antibacterial property against a wide array of microorganisms. Further, the most active plant extracts indicating best antibacterial activity were screened for antifungal activity. The most encouraging plant extract was chosen for facilitate phytochemical and pharmacological activities. This is in pursuance of the endeavors to search for drugs from plants and the verification of the logical basis of some known practices in traditional medicine.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"AN ANALYTICAL STUDY OF ANTIFUNGAL ACTIVITY OF CRUDE EXTRACTS AND ACTIVE CONSTITUENTS OF INDIAN HERBAL PLANTS","attachmentId":58639449,"attachmentType":"pdf","work_url":"https://www.academia.edu/38566617/AN_ANALYTICAL_STUDY_OF_ANTIFUNGAL_ACTIVITY_OF_CRUDE_EXTRACTS_AND_ACTIVE_CONSTITUENTS_OF_INDIAN_HERBAL_PLANTS","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/38566617/AN_ANALYTICAL_STUDY_OF_ANTIFUNGAL_ACTIVITY_OF_CRUDE_EXTRACTS_AND_ACTIVE_CONSTITUENTS_OF_INDIAN_HERBAL_PLANTS"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="56667751" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/56667751/Antimicrobial_activity_of_some_Indian_medicinal_plants">Antimicrobial activity of some Indian medicinal plants</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="5066238" href="https://mdurohtak.academia.edu/RajeshDabur">Rajesh Dabur</a></div><p class="ds-related-work--metadata ds2-5-body-xs">African journal of traditional, complementary, and alternative medicines : AJTCAM / African Networks on Ethnomedicines, 2007</p><p class="ds-related-work--abstract ds2-5-body-sm">The antimicrobial potential of seventy-seven extracts from twenty-four plants was screened against eight bacteria and four pathogenic fungi, using microbroth dilution assay. Lowest concentration of the extract, which inhibits any visual microbial growth after treatment with p-iodonitrotetrazolium violet, was considered to be minimum inhibitory concentration (MIC). Water extracts of Acacia nilotica, Justicia zelanica, Lantana camara and Saraca asoca exhibited good activity against all the bacteria tested and the MIC was recorded in range of 9.375-37.5 microg/ml and 75.0-300.0 microg/ml against the bacterial and fungal pathogens, respectively. The other extracts of Phyllanthus urinaria, Thevetia nerifolia, Jatropha gossypifolia Saraca asoca, Tamarindus indica, Aegle marmelos, Acacia nilotica, Chlorophytum borivilianum, Mangifera indica, Woodfordia fruticosa and Phyllanthus emblica showed antimicrobial activity in a range of 75-1200 microg/ml.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Antimicrobial activity of some Indian medicinal plants","attachmentId":71940347,"attachmentType":"pdf","work_url":"https://www.academia.edu/56667751/Antimicrobial_activity_of_some_Indian_medicinal_plants","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/56667751/Antimicrobial_activity_of_some_Indian_medicinal_plants"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="66677014" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/66677014/Comparative_study_of_the_phytochemicals_and_in_vitro_antimicrobial_potential_of_six_medicinal_plants">Comparative study of the phytochemicals and in vitro antimicrobial potential of six medicinal plants</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="30217632" href="https://independent.academia.edu/AOlaniran">Abiola Olaniran</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2019</p><p class="ds-related-work--abstract ds2-5-body-sm">This study sought to investigate the antimicrobial activity of sixBackground: plants used in traditional medicine in Africa. The antimicrobial activity of the six medicinal plant extracts (aqueousMethods: and ethanol) were evaluated against (ATCC 21784), Proteus mirabilis (ATCC27856) were using thePseudomonas aeruginosa Aspergillus fumigatus agar-well diffusion protocol. The activities of these extracts were compared with the positive controls chloramphenicol and griseofulvin. Similarly, the phytochemicals from the extracts were qualitatively assayed and their percentage yield calculated by standard methods. The bacterial organisms used, and , wereResults: P. mirabilis P. aeruginosa slightly-to-highly susceptible to aqueous and ethanolic extracts from the various test plants, while was insensitive to the treatments. The ethanolic A. fumigatus extracts of the sampled plants showed superior inhibitory performance on the target bacteria to the aqueous extracts. Aqueous and eth...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Comparative study of the phytochemicals and in vitro antimicrobial potential of six medicinal plants","attachmentId":77776043,"attachmentType":"pdf","work_url":"https://www.academia.edu/66677014/Comparative_study_of_the_phytochemicals_and_in_vitro_antimicrobial_potential_of_six_medicinal_plants","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/66677014/Comparative_study_of_the_phytochemicals_and_in_vitro_antimicrobial_potential_of_six_medicinal_plants"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--sticky-ctas","attachmentId":73161058,"attachmentType":"pdf","workUrl":null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--sticky-ctas","attachmentId":73161058,"attachmentType":"pdf","workUrl":null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_73161058" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. 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