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Lori Hoepner - Academia.edu

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href="https://www.academia.edu/20038907/Fractional_exhaled_nitric_oxide_exchange_parameters_among_9_year_old_inner_city_children"><img alt="Research paper thumbnail of Fractional exhaled nitric oxide exchange parameters among 9-year-old inner-city children" class="work-thumbnail" src="https://attachments.academia-assets.com/41261893/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/20038907/Fractional_exhaled_nitric_oxide_exchange_parameters_among_9_year_old_inner_city_children">Fractional exhaled nitric oxide exchange parameters among 9-year-old inner-city children</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://columbia.academia.edu/DiurkaDiaz">Diurka Diaz</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/LHoepner">Lori Hoepner</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://columbia.academia.edu/RachelMiller">Rachel Miller</a></span></div><div class="wp-workCard_item"><span>Pediatric Pulmonology</span><span>, 2011</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="ad1ba748c556e98872e0e63995a91310" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:41261893,&quot;asset_id&quot;:20038907,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/41261893/download_file?st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner 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We hypothesized that the flow independent NO parameters would be associated differentially with wheeze and seroatopy. Methods: As part of a birth cohort study, 9-year-old children (n ¼ 102) of African-American and Dominican mothers living in low-income NYC neighborhoods had FeNO samples collected offline at constant flow rates of 50, 83, and 100 ml/sec. Seroatopy was defined as having measurable (!0.35 IU/ml) specific IgE to any of the five inhalant indoor allergens tested. Current wheeze (last 12 months) was assessed by ISAAC questionnaire. Bronchial NO flux (J NO ) and alveolar NO concentration (C alv ) were estimated by the Pietropaoli and Hogman methods. Results: Valid exhalation flow rates were achieved in 96% of the children. Children with seroatopy (53%) had significantly higher median J NO (522 pl/sec vs. 161 pl/sec, P \u003c 0.001) when compared to nonseroatopic children; however, median C alv was not significantly different between these two groups (5.5 vs. 5.8, P ¼ 0.644). Children with wheeze in the past year (21.6%) had significantly higher median C alv (8.4 ppb vs. 4.9 ppb, P \u003c 0.001), but not J NO (295 pl/sec vs. 165 pl/sec, P ¼ 0.241) when compared with children without wheeze. These associations remained stable after adjustment for known confounders/covariates. Conclusions: The multiple flow method was easily implemented in this pediatric inner-city cohort. In this study population, alveolar concentration of NO may be a better indicator of current wheeze than single flow FeNO. 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mothers with underweight, normal, and overweight prepregnancy BMI" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/24778234/Excessive_gestational_weight_gain_is_associated_with_long_term_body_fat_and_weight_retention_at_7_y_postpartum_in_African_American_and_Dominican_mothers_with_underweight_normal_and_overweight_prepregnancy_BMI">Excessive gestational weight gain is associated with long-term body fat and weight retention at 7 y postpartum in African American and Dominican mothers with underweight, normal, and overweight prepregnancy BMI</a></div><div class="wp-workCard_item"><span>The American journal of clinical nutrition</span><span>, Jan 21, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Excessive gestational weight gain (GWG) is associated with postpartum weight retention (PPWR) and...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Excessive gestational weight gain (GWG) is associated with postpartum weight retention (PPWR) and abdominal adiposity, but long-term effects are understudied in low-income and minority populations at high risk of obesity and associated sequelae. We examined associations between GWG and long-term PPWR and adiposity in a prospective cohort of African American and Dominican mothers in the Bronx and Northern Manhattan. Women (n = 302) were enrolled during pregnancy and were followed for 7 y postpartum. Linear regression was used to relate excessive GWG [greater than 2009 Institute of Medicine (IOM) guidelines] to outcomes [percentage body fat and long-term PPWR (change in weight from prepregnancy to 7 y postpartum)], adjusting for covariates and included an interaction term between prepregnancy body mass index (BMI; in kg/m(2)) and GWG. Mean ± SD prepregnancy BMI and total GWG were 25.6 ± 5.8 (42% of women had BMI ≥25) and 16.6 ± 7.8 kg (64% of women had total GWG greater than IOM guide...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="24778234"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="24778234"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 24778234; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=24778234]").text(description); $(".js-view-count[data-work-id=24778234]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 24778234; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='24778234']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 24778234, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=24778234]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":24778234,"title":"Excessive gestational weight gain is associated with long-term body fat and weight retention at 7 y postpartum in African American and Dominican mothers with underweight, normal, and overweight prepregnancy BMI","translated_title":"","metadata":{"abstract":"Excessive gestational weight gain (GWG) is associated with postpartum weight retention (PPWR) and abdominal adiposity, but long-term effects are understudied in low-income and minority populations at high risk of obesity and associated sequelae. We examined associations between GWG and long-term PPWR and adiposity in a prospective cohort of African American and Dominican mothers in the Bronx and Northern Manhattan. Women (n = 302) were enrolled during pregnancy and were followed for 7 y postpartum. Linear regression was used to relate excessive GWG [greater than 2009 Institute of Medicine (IOM) guidelines] to outcomes [percentage body fat and long-term PPWR (change in weight from prepregnancy to 7 y postpartum)], adjusting for covariates and included an interaction term between prepregnancy body mass index (BMI; in kg/m(2)) and GWG. Mean ± SD prepregnancy BMI and total GWG were 25.6 ± 5.8 (42% of women had BMI ≥25) and 16.6 ± 7.8 kg (64% of women had total GWG greater than IOM guide...","publication_date":{"day":21,"month":1,"year":2015,"errors":{}},"publication_name":"The American journal of clinical nutrition"},"translated_abstract":"Excessive gestational weight gain (GWG) is associated with postpartum weight retention (PPWR) and abdominal adiposity, but long-term effects are understudied in low-income and minority populations at high risk of obesity and associated sequelae. We examined associations between GWG and long-term PPWR and adiposity in a prospective cohort of African American and Dominican mothers in the Bronx and Northern Manhattan. Women (n = 302) were enrolled during pregnancy and were followed for 7 y postpartum. Linear regression was used to relate excessive GWG [greater than 2009 Institute of Medicine (IOM) guidelines] to outcomes [percentage body fat and long-term PPWR (change in weight from prepregnancy to 7 y postpartum)], adjusting for covariates and included an interaction term between prepregnancy body mass index (BMI; in kg/m(2)) and GWG. Mean ± SD prepregnancy BMI and total GWG were 25.6 ± 5.8 (42% of women had BMI ≥25) and 16.6 ± 7.8 kg (64% of women had total GWG greater than IOM guide...","internal_url":"https://www.academia.edu/24778234/Excessive_gestational_weight_gain_is_associated_with_long_term_body_fat_and_weight_retention_at_7_y_postpartum_in_African_American_and_Dominican_mothers_with_underweight_normal_and_overweight_prepregnancy_BMI","translated_internal_url":"","created_at":"2016-04-26T09:50:53.711-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":47333446,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Excessive_gestational_weight_gain_is_associated_with_long_term_body_fat_and_weight_retention_at_7_y_postpartum_in_African_American_and_Dominican_mothers_with_underweight_normal_and_overweight_prepregnancy_BMI","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":47333446,"first_name":"Lori","middle_initials":"","last_name":"Hoepner","page_name":"LHoepner","domain_name":"independent","created_at":"2016-04-19T07:19:51.045-07:00","display_name":"Lori Hoepner","url":"https://independent.academia.edu/LHoepner"},"attachments":[],"research_interests":[{"id":48,"name":"Engineering","url":"https://www.academia.edu/Documents/in/Engineering"},{"id":2808,"name":"Poverty","url":"https://www.academia.edu/Documents/in/Poverty"},{"id":8207,"name":"Risk","url":"https://www.academia.edu/Documents/in/Risk"},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent"},{"id":44962,"name":"Dominican Republic","url":"https://www.academia.edu/Documents/in/Dominican_Republic"},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies"},{"id":62550,"name":"Pregnancy","url":"https://www.academia.edu/Documents/in/Pregnancy"},{"id":63375,"name":"Overweight","url":"https://www.academia.edu/Documents/in/Overweight"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":87786,"name":"New York City","url":"https://www.academia.edu/Documents/in/New_York_City"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult"},{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies"},{"id":192564,"name":"Body Mass Index","url":"https://www.academia.edu/Documents/in/Body_Mass_Index"},{"id":233800,"name":"African Americans","url":"https://www.academia.edu/Documents/in/African_Americans"},{"id":234187,"name":"Recurrence","url":"https://www.academia.edu/Documents/in/Recurrence"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":543452,"name":"Thinness","url":"https://www.academia.edu/Documents/in/Thinness"},{"id":1141692,"name":"Weight Gain","url":"https://www.academia.edu/Documents/in/Weight_Gain"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="24778233"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/24778233/Community_based_focus_groups_guide_epistemological_change_to_educational_materials_at_Columbia_Center_for_Childrens_Environmental_Health"><img alt="Research paper thumbnail of Community-based focus groups guide epistemological change to educational materials at Columbia Center for Children&#39;s Environmental Health" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/24778233/Community_based_focus_groups_guide_epistemological_change_to_educational_materials_at_Columbia_Center_for_Childrens_Environmental_Health">Community-based focus groups guide epistemological change to educational materials at Columbia Center for Children&#39;s Environmental Health</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">BACKGROUND: Environmental exposures during pregnancy and early childhood can lead to adverse outc...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">BACKGROUND: Environmental exposures during pregnancy and early childhood can lead to adverse outcomes in child development. The Columbia Center for Children’s Environmental Health (CCCEH) has linked bisphenol-A (BPA) exposures to anxiety, depressive mood, attention problems and asthma in children. OBJECTIVE: CCCEH’s Community Outreach &amp;Translation Core (COTC) developed an educational brochure showing ways to reduce BPA exposure, using focus groups to ensure materials were culturally relevant for low-income communities of color in Northern Manhattan and South Bronx. METHODS: Three focus groups with women of childbearing age were conducted in English (n= 16) and Spanish (n= 8) using a discussion guide developed with the CCCEH Community Advisory and Stakeholders Board (CASB). Participants were recruited through community-based organizations that serve on CCCEH&amp;#39;s CASB. We discussed participants’ knowledge, beliefs, and health behaviors related to environmental health and BPA. Respon...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="24778233"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="24778233"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 24778233; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=24778233]").text(description); $(".js-view-count[data-work-id=24778233]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 24778233; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='24778233']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 24778233, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=24778233]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":24778233,"title":"Community-based focus groups guide epistemological change to educational materials at Columbia Center for Children's Environmental Health","translated_title":"","metadata":{"abstract":"BACKGROUND: Environmental exposures during pregnancy and early childhood can lead to adverse outcomes in child development. The Columbia Center for Children’s Environmental Health (CCCEH) has linked bisphenol-A (BPA) exposures to anxiety, depressive mood, attention problems and asthma in children. OBJECTIVE: CCCEH’s Community Outreach \u0026Translation Core (COTC) developed an educational brochure showing ways to reduce BPA exposure, using focus groups to ensure materials were culturally relevant for low-income communities of color in Northern Manhattan and South Bronx. METHODS: Three focus groups with women of childbearing age were conducted in English (n= 16) and Spanish (n= 8) using a discussion guide developed with the CCCEH Community Advisory and Stakeholders Board (CASB). Participants were recruited through community-based organizations that serve on CCCEH\u0026#39;s CASB. We discussed participants’ knowledge, beliefs, and health behaviors related to environmental health and BPA. Respon..."},"translated_abstract":"BACKGROUND: Environmental exposures during pregnancy and early childhood can lead to adverse outcomes in child development. The Columbia Center for Children’s Environmental Health (CCCEH) has linked bisphenol-A (BPA) exposures to anxiety, depressive mood, attention problems and asthma in children. OBJECTIVE: CCCEH’s Community Outreach \u0026Translation Core (COTC) developed an educational brochure showing ways to reduce BPA exposure, using focus groups to ensure materials were culturally relevant for low-income communities of color in Northern Manhattan and South Bronx. METHODS: Three focus groups with women of childbearing age were conducted in English (n= 16) and Spanish (n= 8) using a discussion guide developed with the CCCEH Community Advisory and Stakeholders Board (CASB). Participants were recruited through community-based organizations that serve on CCCEH\u0026#39;s CASB. We discussed participants’ knowledge, beliefs, and health behaviors related to environmental health and BPA. Respon...","internal_url":"https://www.academia.edu/24778233/Community_based_focus_groups_guide_epistemological_change_to_educational_materials_at_Columbia_Center_for_Childrens_Environmental_Health","translated_internal_url":"","created_at":"2016-04-26T09:50:53.601-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":47333446,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Community_based_focus_groups_guide_epistemological_change_to_educational_materials_at_Columbia_Center_for_Childrens_Environmental_Health","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":47333446,"first_name":"Lori","middle_initials":"","last_name":"Hoepner","page_name":"LHoepner","domain_name":"independent","created_at":"2016-04-19T07:19:51.045-07:00","display_name":"Lori Hoepner","url":"https://independent.academia.edu/LHoepner"},"attachments":[],"research_interests":[],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="24778232"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/24778232/Prenatal_Exposure_to_Phthalates_and_Childhood_Body_Size_in_an_Urban_Cohort"><img alt="Research paper thumbnail of Prenatal Exposure to Phthalates and Childhood Body Size in an Urban Cohort" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/24778232/Prenatal_Exposure_to_Phthalates_and_Childhood_Body_Size_in_an_Urban_Cohort">Prenatal Exposure to Phthalates and Childhood Body Size in an Urban Cohort</a></div><div class="wp-workCard_item"><span>Environmental health perspectives</span><span>, Jan 12, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Phthalate exposures are hypothesized to increase obesity; however, prior research has been largel...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Phthalate exposures are hypothesized to increase obesity; however, prior research has been largely cross-sectional. To evaluate associations between prenatal phthalate exposures and body mass index (BMI) at child ages 5 and 7 years. Nine metabolites of six phthalates: di-(2-ethylhexyl) phthalate (DEHP), di-n-octyl-, di-iso-butyl-, di-n-butyl-, butylbenzyl-, and diethyl phthalates, were measured in spot urine samples collected from pregnant African American and Dominican women during their third trimester, and from their children at ages 3 and 5 years. To reduce multiple comparison issues, we initially used Principal Component Analysis (PCA) to identify major patterns of (ln)-transformed metabolite concentrations. Height and weight were assessed at ages 5 and 7 years, and fat mass and waist circumference at age 7. Linearized generalized estimating equation analyses related maternal component scores to child anthropometric outcomes at ages 5 (n=326) and 7 (n=330). PCA identified a DEH...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="24778232"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="24778232"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 24778232; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=24778232]").text(description); $(".js-view-count[data-work-id=24778232]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 24778232; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='24778232']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 24778232, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=24778232]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":24778232,"title":"Prenatal Exposure to Phthalates and Childhood Body Size in an Urban Cohort","translated_title":"","metadata":{"abstract":"Phthalate exposures are hypothesized to increase obesity; however, prior research has been largely cross-sectional. To evaluate associations between prenatal phthalate exposures and body mass index (BMI) at child ages 5 and 7 years. Nine metabolites of six phthalates: di-(2-ethylhexyl) phthalate (DEHP), di-n-octyl-, di-iso-butyl-, di-n-butyl-, butylbenzyl-, and diethyl phthalates, were measured in spot urine samples collected from pregnant African American and Dominican women during their third trimester, and from their children at ages 3 and 5 years. To reduce multiple comparison issues, we initially used Principal Component Analysis (PCA) to identify major patterns of (ln)-transformed metabolite concentrations. Height and weight were assessed at ages 5 and 7 years, and fat mass and waist circumference at age 7. Linearized generalized estimating equation analyses related maternal component scores to child anthropometric outcomes at ages 5 (n=326) and 7 (n=330). PCA identified a DEH...","publication_date":{"day":12,"month":1,"year":2015,"errors":{}},"publication_name":"Environmental health perspectives"},"translated_abstract":"Phthalate exposures are hypothesized to increase obesity; however, prior research has been largely cross-sectional. To evaluate associations between prenatal phthalate exposures and body mass index (BMI) at child ages 5 and 7 years. Nine metabolites of six phthalates: di-(2-ethylhexyl) phthalate (DEHP), di-n-octyl-, di-iso-butyl-, di-n-butyl-, butylbenzyl-, and diethyl phthalates, were measured in spot urine samples collected from pregnant African American and Dominican women during their third trimester, and from their children at ages 3 and 5 years. To reduce multiple comparison issues, we initially used Principal Component Analysis (PCA) to identify major patterns of (ln)-transformed metabolite concentrations. Height and weight were assessed at ages 5 and 7 years, and fat mass and waist circumference at age 7. Linearized generalized estimating equation analyses related maternal component scores to child anthropometric outcomes at ages 5 (n=326) and 7 (n=330). PCA identified a DEH...","internal_url":"https://www.academia.edu/24778232/Prenatal_Exposure_to_Phthalates_and_Childhood_Body_Size_in_an_Urban_Cohort","translated_internal_url":"","created_at":"2016-04-26T09:50:53.488-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":47333446,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Prenatal_Exposure_to_Phthalates_and_Childhood_Body_Size_in_an_Urban_Cohort","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":47333446,"first_name":"Lori","middle_initials":"","last_name":"Hoepner","page_name":"LHoepner","domain_name":"independent","created_at":"2016-04-19T07:19:51.045-07:00","display_name":"Lori Hoepner","url":"https://independent.academia.edu/LHoepner"},"attachments":[],"research_interests":[{"id":58054,"name":"Environmental Sciences","url":"https://www.academia.edu/Documents/in/Environmental_Sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="24778231"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/24778231/Gestational_weight_gain_and_obesity_adiposity_and_body_size_in_African_American_and_Dominican_children_in_the_Bronx_and_Northern_Manhattan"><img alt="Research paper thumbnail of Gestational weight gain and obesity, adiposity and body size in African-American and Dominican children in the Bronx and Northern Manhattan" class="work-thumbnail" src="https://attachments.academia-assets.com/45106270/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/24778231/Gestational_weight_gain_and_obesity_adiposity_and_body_size_in_African_American_and_Dominican_children_in_the_Bronx_and_Northern_Manhattan">Gestational weight gain and obesity, adiposity and body size in African-American and Dominican children in the Bronx and Northern Manhattan</a></div><div class="wp-workCard_item"><span>Maternal &amp; Child Nutrition</span><span>, 2015</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="06e05b8ff008a0f74df23cc632b0fa25" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:45106270,&quot;asset_id&quot;:24778231,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/45106270/download_file?st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="24778231"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="24778231"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 24778231; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=24778231]").text(description); $(".js-view-count[data-work-id=24778231]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 24778231; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='24778231']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 24778231, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); 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We examined the association between GWG and child anthropometric measures and body composition at 7 years [waist circumference (WC), body mass index z-score (BMIZ), obesity (BMIZ ≥95%ile) and bioelectrical impedance analysis estimates of percentage body fat (%fat)] in African-American and Dominican dyads (n = 323) in the Columbia Center for Children's Environmental Health prospective birth cohort study from 1998 to 2013. Linear and logistic regression evaluated associations between excessive GWG [\u003eInstitute of Medicine (IOM) 2009 guidelines] and outcomes, adjusting for pre-pregnancy BMI and covariates. Pre-pregnancy BMI (mean ± standard deviation, all such values) and total GWG were 25.8 ± 6.2 kg m −2 (45% overweight/ obese) and 16.4 ± 7.9 kg (64% \u003e IOM guidelines), respectively. Excessive GWG was associated with higher BMIZ {0.44 [95% confidence interval (CI): 0.2, 0.7], P \u003c 0.001}, WC [β: 2.9 cm (95% CI: 1.1, 4.6), P = 0.002], %fat at 7 years [β: 2.2% (95% CI: 1.0, 3.5), P = 0.001)] and obesity [odds ratio: 2.93 (95% CI: 1.5, 5.8), P = 0.002]. Pre-pregnancy BMI was positively associated with child size, adiposity and obesity (all P \u003c 0.05). Excessive GWG was highly prevalent and was associated with child obesity, greater percentage body fat and abdominal adiposity. Strategies to support healthy GWG are warranted to promote healthy growth and prevent childhood obesity.","publication_date":{"day":null,"month":null,"year":2015,"errors":{}},"publication_name":"Maternal \u0026 Child Nutrition","grobid_abstract_attachment_id":45106270},"translated_abstract":null,"internal_url":"https://www.academia.edu/24778231/Gestational_weight_gain_and_obesity_adiposity_and_body_size_in_African_American_and_Dominican_children_in_the_Bronx_and_Northern_Manhattan","translated_internal_url":"","created_at":"2016-04-26T09:50:53.389-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":47333446,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":45106270,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/45106270/thumbnails/1.jpg","file_name":"Gestational_weight_gain_and_obesity_adip20160426-7877-1lylm2r.pdf","download_url":"https://www.academia.edu/attachments/45106270/download_file?st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Gestational_weight_gain_and_obesity_adip.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/45106270/Gestational_weight_gain_and_obesity_adip20160426-7877-1lylm2r-libre.pdf?1461689793=\u0026response-content-disposition=attachment%3B+filename%3DGestational_weight_gain_and_obesity_adip.pdf\u0026Expires=1732420691\u0026Signature=Zv-2TV-7A4~qvkCPUzF1~vIE-yZPE0T1qVu1dhZSmZ0eUATsmg-S4LLiPqSkRp9owMOFIexf2fmWhxdsAbFpucFqrQXo9ks7llXZ9brG8pkY16ERO8dsomALnucpPrBnnhu4XPoVR~9CqzVFjGc1T4~60rErgBtyhzlQX7U7~BRr0uwZDl7WHlx8j6sHa6Cp0q0u7svQtr1ktV3vUtNHqGGLa9KJWed0iQ9YalT~B57AeBfQTIWBa1DceSOHXv6lTJlGA7YaBsKpzLR0ZNoYOXNnT08tRIAqtboZPszALNmRt6axUr01bqQKWnfdEOtrtC6~eAd5P4ICkgbdSlQn4A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Gestational_weight_gain_and_obesity_adiposity_and_body_size_in_African_American_and_Dominican_children_in_the_Bronx_and_Northern_Manhattan","translated_slug":"","page_count":11,"language":"en","content_type":"Work","owner":{"id":47333446,"first_name":"Lori","middle_initials":"","last_name":"Hoepner","page_name":"LHoepner","domain_name":"independent","created_at":"2016-04-19T07:19:51.045-07:00","display_name":"Lori Hoepner","url":"https://independent.academia.edu/LHoepner"},"attachments":[{"id":45106270,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/45106270/thumbnails/1.jpg","file_name":"Gestational_weight_gain_and_obesity_adip20160426-7877-1lylm2r.pdf","download_url":"https://www.academia.edu/attachments/45106270/download_file?st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Gestational_weight_gain_and_obesity_adip.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/45106270/Gestational_weight_gain_and_obesity_adip20160426-7877-1lylm2r-libre.pdf?1461689793=\u0026response-content-disposition=attachment%3B+filename%3DGestational_weight_gain_and_obesity_adip.pdf\u0026Expires=1732420691\u0026Signature=Zv-2TV-7A4~qvkCPUzF1~vIE-yZPE0T1qVu1dhZSmZ0eUATsmg-S4LLiPqSkRp9owMOFIexf2fmWhxdsAbFpucFqrQXo9ks7llXZ9brG8pkY16ERO8dsomALnucpPrBnnhu4XPoVR~9CqzVFjGc1T4~60rErgBtyhzlQX7U7~BRr0uwZDl7WHlx8j6sHa6Cp0q0u7svQtr1ktV3vUtNHqGGLa9KJWed0iQ9YalT~B57AeBfQTIWBa1DceSOHXv6lTJlGA7YaBsKpzLR0ZNoYOXNnT08tRIAqtboZPszALNmRt6axUr01bqQKWnfdEOtrtC6~eAd5P4ICkgbdSlQn4A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":591,"name":"Nutrition and Dietetics","url":"https://www.academia.edu/Documents/in/Nutrition_and_Dietetics"},{"id":38359,"name":"Maternal and Child Nutrition","url":"https://www.academia.edu/Documents/in/Maternal_and_Child_Nutrition"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="24778230"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/24778230/Preliminary_Findings_from_the_New_York_City_Neighborhood_Asthma_and_Allergy_Study"><img alt="Research paper thumbnail of Preliminary Findings from the New York City Neighborhood Asthma and Allergy Study" class="work-thumbnail" src="https://attachments.academia-assets.com/45106271/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/24778230/Preliminary_Findings_from_the_New_York_City_Neighborhood_Asthma_and_Allergy_Study">Preliminary Findings from the New York City Neighborhood Asthma and Allergy Study</a></div><div class="wp-workCard_item"><span>Journal of Allergy and Clinical Immunology</span><span>, 2009</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="2d563f13e99a5664f871823d7bbf914c" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:45106271,&quot;asset_id&quot;:24778230,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/45106271/download_file?st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="24778230"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="24778230"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 24778230; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=24778230]").text(description); $(".js-view-count[data-work-id=24778230]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 24778230; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='24778230']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 24778230, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "2d563f13e99a5664f871823d7bbf914c" } } $('.js-work-strip[data-work-id=24778230]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":24778230,"title":"Preliminary Findings from the New York City Neighborhood Asthma and Allergy Study","translated_title":"","metadata":{"grobid_abstract":"RATIONALE: Since traditional farming represents a unique model situation to investigate the relationship of early-life microbial exposure and allergy protection. associations between maternal farming exposures and cytokine production in cord blood mononuclear cells in a prospective multi-national birth cohort of 530 farm and 603 non-farm children and their families. METHODS: Supernatants from stimulated CB mononuclear cells were assessed for the production of IL-5, IFN-g, IL-10 IL-12 and TNF-a by using ELISA-assays. Associations between maternal farming exposures and the porduction of cord blood cytokines were assessed by using a Tobit-regression model. RESULTS: Cord blood from farmer children showed significantly higher levels of TNF-a and IFN-g production compared to cord blood non-farmer children, whereas IL-10, IL-12 and IL-5 levels did not differ between these study groups. Elevated TNF-a and IFN-g levels in cord blood were associated with maternal exposures to farm animals, animal sheds, hay lofts, farm milk and farm milk products during pregnancy. CONCLUSIONS: Maternal exposure to farming activities and farm products during pregnancy modulated cytokine production patterns of their offspring at birth.","publication_date":{"day":null,"month":null,"year":2009,"errors":{}},"publication_name":"Journal of Allergy and Clinical Immunology","grobid_abstract_attachment_id":45106271},"translated_abstract":null,"internal_url":"https://www.academia.edu/24778230/Preliminary_Findings_from_the_New_York_City_Neighborhood_Asthma_and_Allergy_Study","translated_internal_url":"","created_at":"2016-04-26T09:50:53.286-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":47333446,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":45106271,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/45106271/thumbnails/1.jpg","file_name":"j.jaci.2008.12.093.pdf20160426-12263-1g2ynft","download_url":"https://www.academia.edu/attachments/45106271/download_file?st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Preliminary_Findings_from_the_New_York_C.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/45106271/j.jaci.2008.12.093-libre.pdf20160426-12263-1g2ynft?1461689792=\u0026response-content-disposition=attachment%3B+filename%3DPreliminary_Findings_from_the_New_York_C.pdf\u0026Expires=1732420691\u0026Signature=R1PBf0Y4YBYZx6PHh39h-opOxGtTBZGLgg3XN1bvxVi98kYEU~Sipm1EJ1fitcQSX3xLLirI06IgjQ2OV36dEjoaZSifn8xu5dscj9FIwg~iw6oLD-871HGW-APGLguKLLmhLsepJK-2UUXhXBFbLIOCziIzGlr5~~utUTfp~neVOiHeQLV9Vld7urqEXIFm9yGtpaFRJ5htruwiH3Y2V6LV4DEHyR49PZG5NPpN~emEoVckqzvECB7Zhz2xnqAC2VfdWztdfgHMSRUB50D~~UFLn39rCRJh1Mkv4DXMwbAKz2F1EXPmHFLzg7kaoIlObh~-ZTiSMvOdsCcTreaJxg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Preliminary_Findings_from_the_New_York_City_Neighborhood_Asthma_and_Allergy_Study","translated_slug":"","page_count":1,"language":"en","content_type":"Work","owner":{"id":47333446,"first_name":"Lori","middle_initials":"","last_name":"Hoepner","page_name":"LHoepner","domain_name":"independent","created_at":"2016-04-19T07:19:51.045-07:00","display_name":"Lori Hoepner","url":"https://independent.academia.edu/LHoepner"},"attachments":[{"id":45106271,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/45106271/thumbnails/1.jpg","file_name":"j.jaci.2008.12.093.pdf20160426-12263-1g2ynft","download_url":"https://www.academia.edu/attachments/45106271/download_file?st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Preliminary_Findings_from_the_New_York_C.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/45106271/j.jaci.2008.12.093-libre.pdf20160426-12263-1g2ynft?1461689792=\u0026response-content-disposition=attachment%3B+filename%3DPreliminary_Findings_from_the_New_York_C.pdf\u0026Expires=1732420691\u0026Signature=R1PBf0Y4YBYZx6PHh39h-opOxGtTBZGLgg3XN1bvxVi98kYEU~Sipm1EJ1fitcQSX3xLLirI06IgjQ2OV36dEjoaZSifn8xu5dscj9FIwg~iw6oLD-871HGW-APGLguKLLmhLsepJK-2UUXhXBFbLIOCziIzGlr5~~utUTfp~neVOiHeQLV9Vld7urqEXIFm9yGtpaFRJ5htruwiH3Y2V6LV4DEHyR49PZG5NPpN~emEoVckqzvECB7Zhz2xnqAC2VfdWztdfgHMSRUB50D~~UFLn39rCRJh1Mkv4DXMwbAKz2F1EXPmHFLzg7kaoIlObh~-ZTiSMvOdsCcTreaJxg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":1290,"name":"Immunology","url":"https://www.academia.edu/Documents/in/Immunology"},{"id":87786,"name":"New York City","url":"https://www.academia.edu/Documents/in/New_York_City"},{"id":1826493,"name":"Clinical Allergy and Immunology","url":"https://www.academia.edu/Documents/in/Clinical_Allergy_and_Immunology"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="24778229"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/24778229/Abstract_LB_402_Chromosomal_aberrations_in_5_year_olds_and_urinary_PAH_metabolites"><img alt="Research paper thumbnail of Abstract LB-402: Chromosomal aberrations in 5-year olds and urinary PAH metabolites" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div 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class="js-work-strip profile--work_container" data-work-id="24561060"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/24561060/HIV_prevention_with_severely_mentally_ill_men_A_randomised_controlled_trial"><img alt="Research paper thumbnail of HIV prevention with severely mentally ill men: A randomised controlled trial" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/24561060/HIV_prevention_with_severely_mentally_ill_men_A_randomised_controlled_trial">HIV prevention with severely mentally ill men: A randomised controlled trial</a></div><div class="wp-workCard_item"><span>AIDS Care</span><span>, 2007</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">We conducted a randomised clinical trial to test the efficacy of an enhanced version of an interv...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">We conducted a randomised clinical trial to test the efficacy of an enhanced version of an intervention previously shown to reduce HIV sexual risk behaviours among men with severe mental illness. One-hundred-and-forty-nine subjects aged 18-59 years were randomly assigned to the experimental or control conditions. Sexual risk behaviours were assessed every three months for 12-months. The primary analysis compared experimental and control groups with respect to sexual risk behaviours with casual partners as measured by the Vaginal Episodes Equivalent (VEE) score. Additional analyses included comparison of VEE scores of those men sexually active in the three months prior to baseline and the proportion of condom-protected sexual acts with casual partners. There were no significant differences in sexual risk behaviours with casual partners between experimental and control subjects. Additional analyses demonstrated a trend toward sexual risk reduction at six months post-intervention (p=0.06) but not at 12 months. These results may reflect a lack of efficacy or a true reduction in risk that the trial was underpowered to detect at the 0.05-level. If there was a true reduction in risk, it was not maintained after the initial six months.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="24561060"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="24561060"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 24561060; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=24561060]").text(description); $(".js-view-count[data-work-id=24561060]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 24561060; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='24561060']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 24561060, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=24561060]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":24561060,"title":"HIV prevention with severely mentally ill men: A randomised controlled trial","translated_title":"","metadata":{"abstract":"We conducted a randomised clinical trial to test the efficacy of an enhanced version of an intervention previously shown to reduce HIV sexual risk behaviours among men with severe mental illness. One-hundred-and-forty-nine subjects aged 18-59 years were randomly assigned to the experimental or control conditions. Sexual risk behaviours were assessed every three months for 12-months. The primary analysis compared experimental and control groups with respect to sexual risk behaviours with casual partners as measured by the Vaginal Episodes Equivalent (VEE) score. Additional analyses included comparison of VEE scores of those men sexually active in the three months prior to baseline and the proportion of condom-protected sexual acts with casual partners. There were no significant differences in sexual risk behaviours with casual partners between experimental and control subjects. Additional analyses demonstrated a trend toward sexual risk reduction at six months post-intervention (p=0.06) but not at 12 months. These results may reflect a lack of efficacy or a true reduction in risk that the trial was underpowered to detect at the 0.05-level. If there was a true reduction in risk, it was not maintained after the initial six months.","publication_date":{"day":null,"month":null,"year":2007,"errors":{}},"publication_name":"AIDS Care"},"translated_abstract":"We conducted a randomised clinical trial to test the efficacy of an enhanced version of an intervention previously shown to reduce HIV sexual risk behaviours among men with severe mental illness. One-hundred-and-forty-nine subjects aged 18-59 years were randomly assigned to the experimental or control conditions. Sexual risk behaviours were assessed every three months for 12-months. The primary analysis compared experimental and control groups with respect to sexual risk behaviours with casual partners as measured by the Vaginal Episodes Equivalent (VEE) score. Additional analyses included comparison of VEE scores of those men sexually active in the three months prior to baseline and the proportion of condom-protected sexual acts with casual partners. There were no significant differences in sexual risk behaviours with casual partners between experimental and control subjects. Additional analyses demonstrated a trend toward sexual risk reduction at six months post-intervention (p=0.06) but not at 12 months. These results may reflect a lack of efficacy or a true reduction in risk that the trial was underpowered to detect at the 0.05-level. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="12494661"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/12494661/1_Effects_of_Season_and_Indoor_Heating_on_Indoor_and_Outdoor_Residential_Levels_of_Airborne_Polycyclic_Aromatic_Hydrocarbons_Absorbance_and_Particulate_Matter_2_5_in_an_Inner_City_Cohort_of_Young_Children"><img alt="Research paper thumbnail of 1. Effects of Season and Indoor Heating on Indoor and Outdoor Residential Levels of Airborne Polycyclic Aromatic Hydrocarbons, Absorbance and Particulate Matter 2.5 in an Inner City Cohort of Young Children" class="work-thumbnail" src="https://attachments.academia-assets.com/46143567/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/12494661/1_Effects_of_Season_and_Indoor_Heating_on_Indoor_and_Outdoor_Residential_Levels_of_Airborne_Polycyclic_Aromatic_Hydrocarbons_Absorbance_and_Particulate_Matter_2_5_in_an_Inner_City_Cohort_of_Young_Children">1. Effects of Season and Indoor Heating on Indoor and Outdoor Residential Levels of Airborne Polycyclic Aromatic Hydrocarbons, Absorbance and Particulate Matter 2.5 in an Inner City Cohort of Young Children</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/LHoepner">Lori Hoepner</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/StevenChillrud">Steven Chillrud</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/DavidCamann">David Camann</a></span></div><div class="wp-workCard_item"><span>Journal of Allergy and Clinical Immunology</span><span>, 2010</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="65cf1f2a1d508219364e37592d6f600c" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:46143567,&quot;asset_id&quot;:12494661,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/46143567/download_file?st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="12494661"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="12494661"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 12494661; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=12494661]").text(description); $(".js-view-count[data-work-id=12494661]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 12494661; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='12494661']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 12494661, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "65cf1f2a1d508219364e37592d6f600c" } } $('.js-work-strip[data-work-id=12494661]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":12494661,"title":"1. Effects of Season and Indoor Heating on Indoor and Outdoor Residential Levels of Airborne Polycyclic Aromatic Hydrocarbons, Absorbance and Particulate Matter 2.5 in an Inner City Cohort of Young Children","translated_title":"","metadata":{"grobid_abstract":"RATIONALE: Freshwater and marine cyanobacteria and dinoflagelates are known to elaborate toxins which induce inflammatory rashes and cough in exposed swimmers. The immune mechanism of inflammatory reactions is unknown but clinical symptoms such as erythematous pruritic rashes are common. We used purified marine toxins; debromaplysiatoxins, lyngbyatoxin-a, saxitoxin, and brevatoxin to determine induction of immune activation of human cells ex vivo. METHODS: Meyelomonocytic (U937) cell lines, T-cell (Jurkat) lines, and peripheral mononuclear cells (PBMC) were exposed to the panel of aquatic toxins with lipopolysacchride (LPS) serving as a positive control. Assessment of cell viability and cell cycle analysis was performed using propidium idodide. Elaboration of pro-inflammatory cytokine production by cells cultured with toxins for 48 hours were measured using flow cytometry-based cytokine bead arrays. RESULTS: Toxin concentrations were selected that did not induce cell death. Lyngbyatoxin-a induced G0 cell cycle arrest in U937 cells. When compared to media alone PBMCs exposed to Lyngbyatoxin-a produced significant levels of TNFa, IL-6, IL-1B, IL-10, IL-4, and IL-5 but had no effect on INFg or IL-12 production. The magnitude was similar to PBMC incubated with LPS. None of the other marine toxins tested induced cytokine production by PBMC. CONCLUSIONS: Lyngbyatoxin-a induces macrophage derived pro-inflammatory cytokines and monocyte differentiation ex vivo. The cytokine pattern suggests that it may be mediated through TLR-4 binding. In addition, high levels of the TH2 cytokines IL-4 and IL-5 indicate that these cytokines modulate a TH2 immune response potentially explaining the clinical manifestations seen in individuals following exposure.","publication_date":{"day":null,"month":null,"year":2010,"errors":{}},"publication_name":"Journal of Allergy and Clinical Immunology","grobid_abstract_attachment_id":46143567},"translated_abstract":null,"internal_url":"https://www.academia.edu/12494661/1_Effects_of_Season_and_Indoor_Heating_on_Indoor_and_Outdoor_Residential_Levels_of_Airborne_Polycyclic_Aromatic_Hydrocarbons_Absorbance_and_Particulate_Matter_2_5_in_an_Inner_City_Cohort_of_Young_Children","translated_internal_url":"","created_at":"2015-05-20T13:22:18.039-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":31351195,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":17339963,"work_id":12494661,"tagging_user_id":31351195,"tagged_user_id":47333446,"co_author_invite_id":396777,"email":"l***5@columbia.edu","display_order":0,"name":"Lori Hoepner","title":"1. 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Methods: Mono-n-butyl phthalate (MnBP), monobenzyl phthalate (MBzP), monoisobutyl phthalate (MiBP), and four di-2-ethylhexyl phthalate metabolites were measured in a spot urine sample collected from 319 women during the third trimester. When children were 3 years of age, the Mental Development Index (MDI) and Psychomotor Development Index (PDI) were measured using the Bayley Scales of Infant Development II, and behavior problems were assessed by maternal report on the Child Behavior Checklist. results: Child PDI scores decreased with increasing log e MnBP [estimated adjusted β-coefficient = -2.81; 95% confidence interval (CI): -4.63, -1.0] and log e MiBP (β = -2.28; 95% CI: -3.90, -0.67); odds of motor delay increased significantly [per log e MnBP: estimated adjusted odds ratio (OR) = 1.64; 95% CI: 1.10, 2.44; per log e MiBP: adjusted OR =1.82; 95% CI: 1.24, 2.66]. In girls, MDI scores decreased with increasing log e MnBP (β = -2.67; 95% CI: -4.70, -0.65); the child sex difference in odds of mental delay was significant (p = 0.037). The ORs for clinically withdrawn behavior were 2.23 (95% CI: 1.27, 3.92) and 1.57 (95% CI: 1.07, 2.31) per log e unit increase in MnBP and MBzP, respectively; for clinically internalizing behaviors, the OR was 1.43 (95% CI: 1.01, 1.90) per log e unit increase in MBzP. Significant child sex differences were seen in associations between MnBP and MBzP and behaviors in internalizing domains (p \u003c 0.05). conclusion: Certain prenatal phthalate exposures may decrease child mental and motor development and increase internalizing behaviors. key words: behavior, child, mental, phthalates, prenatal, psychomotor. 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wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/24555600/Prenatal_exposure_to_antibiotics_cesarean_section_and_risk_of_childhood_obesity">Prenatal exposure to antibiotics, cesarean section and risk of childhood obesity</a></div><div class="wp-workCard_item"><span>International journal of obesity (2005)</span><span>, Jan 11, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background/Objectives:Cesarean section (CS) and antibiotic use during pregnancy may alter normal ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background/Objectives:Cesarean section (CS) and antibiotic use during pregnancy may alter normal maternal-offspring microbiota exchange, thereby contributing to aberrant microbial colonization of the infant gut and increased susceptibility to obesity later in life. We hypothesized that (i) maternal use of antibiotics in the second or third trimester of pregnancy and (ii) CS are independently associated with higher risk of childhood obesity in the offspring.Subjects/Methods:Of the 727 mothers enrolled in the Northern Manhattan Mothers and Children Study, we analyzed the 436 mother-child dyads followed until 7 years of age with complete data. We ascertained prenatal antibiotic use by a questionnaire administered late in the third trimester, and delivery mode by medical record. We derived age- and sex-specific body mass index (BMI) z-scores using the CDC SAS Macro, and defined obesity as BMI z⩾95th percentile. We used binary regression with robust variance and linear regression models ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="362de751ca033778bcf9e2fa47f3ae69" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:44885809,&quot;asset_id&quot;:24555600,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/44885809/download_file?st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="24555600"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="24555600"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 24555600; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=24555600]").text(description); $(".js-view-count[data-work-id=24555600]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 24555600; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='24555600']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 24555600, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "362de751ca033778bcf9e2fa47f3ae69" } } $('.js-work-strip[data-work-id=24555600]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":24555600,"title":"Prenatal exposure to antibiotics, cesarean section and risk of childhood obesity","translated_title":"","metadata":{"abstract":"Background/Objectives:Cesarean section (CS) and antibiotic use during pregnancy may alter normal maternal-offspring microbiota exchange, thereby contributing to aberrant microbial colonization of the infant gut and increased susceptibility to obesity later in life. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="24555599"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/24555599/Prenatal_phthalate_and_early_childhood_bisphenol_A_exposures_increase_asthma_risk_in_inner_city_children"><img alt="Research paper thumbnail of Prenatal phthalate and early childhood bisphenol A exposures increase asthma risk in inner-city children" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/24555599/Prenatal_phthalate_and_early_childhood_bisphenol_A_exposures_increase_asthma_risk_in_inner_city_children">Prenatal phthalate and early childhood bisphenol A exposures increase asthma risk in inner-city children</a></div><div class="wp-workCard_item"><span>The Journal of allergy and clinical immunology</span><span>, 2014</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="24555599"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="24555599"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 24555599; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="24555598"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/24555598/Vinyl_flooring_in_the_home_is_associated_with_childrens_airborne_butylbenzyl_phthalate_and_urinary_metabolite_concentrations"><img alt="Research paper thumbnail of Vinyl flooring in the home is associated with children&#39;s airborne butylbenzyl phthalate and urinary metabolite concentrations" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/24555598/Vinyl_flooring_in_the_home_is_associated_with_childrens_airborne_butylbenzyl_phthalate_and_urinary_metabolite_concentrations">Vinyl flooring in the home is associated with children&#39;s airborne butylbenzyl phthalate and urinary metabolite concentrations</a></div><div class="wp-workCard_item"><span>Journal of exposure science &amp; environmental epidemiology</span><span>, Jan 18, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Prior studies have shown that vinyl flooring as well as the vinyl-softening plasticizers butylben...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Prior studies have shown that vinyl flooring as well as the vinyl-softening plasticizers butylbenzyl phthalate (BBzP) and di(2-ethylhexyl) phthalate (DEHP) are associated with asthma and airway inflammation. Although DEHP exposure is primarily dietary, whether home vinyl flooring contributes to indoor air and urinary metabolite concentrations for these two phthalates is unclear. Exposures to BBzP and DEHP were examined in a prospective birth cohort of New York City children (n=239) using: (i) visual observation of potential phthalate containing flooring, (ii) a 2-week home indoor air sample, and (iii) concurrent urinary metabolites in a subset (n=193). The category &amp;quot;vinyl or linoleum&amp;quot; flooring was observed in 135 (56%) of monitored rooms; these rooms had statistically significantly higher indoor air geometric mean concentrations of BBzP (23.9 ng/m(3)) than rooms with wood or carpet flooring (10.6 ng/m(3)). 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Children from homes with \u0026quot;vinyl or linoleum\u0026quot; flooring als...","publication_date":{"day":18,"month":1,"year":2015,"errors":{}},"publication_name":"Journal of exposure science \u0026 environmental epidemiology"},"translated_abstract":"Prior studies have shown that vinyl flooring as well as the vinyl-softening plasticizers butylbenzyl phthalate (BBzP) and di(2-ethylhexyl) phthalate (DEHP) are associated with asthma and airway inflammation. Although DEHP exposure is primarily dietary, whether home vinyl flooring contributes to indoor air and urinary metabolite concentrations for these two phthalates is unclear. Exposures to BBzP and DEHP were examined in a prospective birth cohort of New York City children (n=239) using: (i) visual observation of potential phthalate containing flooring, (ii) a 2-week home indoor air sample, and (iii) concurrent urinary metabolites in a subset (n=193). 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Exhaled No At Age 7-11 Years Is Elevated With Early Life But Not Recent Onset Of Allergic ...","internal_url":"https://www.academia.edu/24555596/Exhaled_No_At_Age_7_11_Years_Is_Elevated_With_Early_Life_But_Not_Recent_Onset_Of_Allergic_Sensitization","translated_internal_url":"","created_at":"2016-04-19T07:20:44.847-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":47333446,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":19203249,"work_id":24555596,"tagging_user_id":47333446,"tagged_user_id":null,"co_author_invite_id":128915,"email":"f***1@columbia.cdu","display_order":0,"name":"Frederica Perera","title":"Exhaled No At Age 7-11 Years Is Elevated With Early Life But Not Recent Onset Of Allergic Sensitization"}],"downloadable_attachments":[],"slug":"Exhaled_No_At_Age_7_11_Years_Is_Elevated_With_Early_Life_But_Not_Recent_Onset_Of_Allergic_Sensitization","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":47333446,"first_name":"Lori","middle_initials":"","last_name":"Hoepner","page_name":"LHoepner","domain_name":"independent","created_at":"2016-04-19T07:19:51.045-07:00","display_name":"Lori Hoepner","url":"https://independent.academia.edu/LHoepner"},"attachments":[],"research_interests":[{"id":151448,"name":"American","url":"https://www.academia.edu/Documents/in/American"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14745252"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/14745252/Association_of_recent_exposure_to_ambient_metals_on_fractional_exhaled_nitric_oxide_in_9_11_year_old_inner_city_children"><img alt="Research paper thumbnail of Association of recent exposure to ambient metals on fractional exhaled nitric oxide in 9-11 year old inner-city children" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/14745252/Association_of_recent_exposure_to_ambient_metals_on_fractional_exhaled_nitric_oxide_in_9_11_year_old_inner_city_children">Association of recent exposure to ambient metals on fractional exhaled nitric oxide in 9-11 year old inner-city children</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://udesc.academia.edu/MariaRosa">Maria Rosa</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/LHoepner">Lori Hoepner</a></span></div><div class="wp-workCard_item"><span>Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society</span><span>, Jan 31, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Exposure to ambient metals in urban environments has been associated with wheeze, and emergency r...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Exposure to ambient metals in urban environments has been associated with wheeze, and emergency room visits and hospitalizations due to respiratory illness. However, the effect of ambient metals exposure on airway inflammation, and how these associations may be modified by seroatopy, has not been determined. Fractional exhaled nitric oxide (FENO) is a reliable proxy marker of airway inflammation. We hypothesized that recent ambient concentrations of Ni, V, Zn and Fe would be associated differentially with proximal and distal fractions of exhaled NO, and that these associations would be modified by seroatopy. As part of the Columbia Center for Children&amp;#39;s Environmental Health (CCCEH) birth cohort study, 9-11 year old children (n=192) were evaluated. Ambient measures of Ni, V, Zn and Fe were obtained from a local central monitoring site and averaged over 9 days based on three 24h measures every third day. 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However, the effect of ambient metals exposure on airway inflammation, and how these associations may be modified by seroatopy, has not been determined. Fractional exhaled nitric oxide (FENO) is a reliable proxy marker of airway inflammation. We hypothesized that recent ambient concentrations of Ni, V, Zn and Fe would be associated differentially with proximal and distal fractions of exhaled NO, and that these associations would be modified by seroatopy. As part of the Columbia Center for Children\u0026#39;s Environmental Health (CCCEH) birth cohort study, 9-11 year old children (n=192) were evaluated. Ambient measures of Ni, V, Zn and Fe were obtained from a local central monitoring site and averaged over 9 days based on three 24h measures every third day. 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As part of the Columbia Center for Children\u0026#39;s Environmental Health (CCCEH) birth cohort study, 9-11 year old children (n=192) were evaluated. Ambient measures of Ni, V, Zn and Fe were obtained from a local central monitoring site and averaged over 9 days based on three 24h measures every third day. 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Exposure","url":"https://www.academia.edu/Documents/in/Environmental_Exposure"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="24555595"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/24555595/Asthma_in_Inner_City_Children_at_5_11_Years_of_Age_and_Prenatal_Exposure_to_Phthalates_The_Columbia_Center_for_Children_s_Environmental_Health_Cohort"><img alt="Research paper thumbnail of Asthma in Inner-City Children at 5-11 Years of Age and Prenatal Exposure to Phthalates: The Columbia Center for Children’s Environmental Health Cohort" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/24555595/Asthma_in_Inner_City_Children_at_5_11_Years_of_Age_and_Prenatal_Exposure_to_Phthalates_The_Columbia_Center_for_Children_s_Environmental_Health_Cohort">Asthma in Inner-City Children at 5-11 Years of Age and Prenatal Exposure to Phthalates: The Columbia Center for Children’s Environmental Health Cohort</a></div><div class="wp-workCard_item"><span>Environmental Health Perspectives</span><span>, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Studies suggest that phthalate exposures may adversely affect child respiratory health. We evalua...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Studies suggest that phthalate exposures may adversely affect child respiratory health. We evaluated associations between asthma diagnosed in children between 5 and 11 years of age and prenatal exposures to butylbenzyl phthalate (BBzP), di-n-butyl phthalate (DnBP), di(2-ethylhexyl) phthalate (DEHP), and diethyl phthalate (DEP). Phthalate metabolites were measured in spot urine collected from 300 pregnant inner-city women. Children were examined by an allergist or pulmonologist based on the first parental report of wheeze, other respiratory symptoms, and/or use of asthma rescue/controller medication in the preceding 12 months on repeat follow-up questionnaires. Standardized diagnostic criteria were used to classify these children as either having or not having current asthma at the time of the physician examination. Children without any report of wheeze or the other asthma-like symptoms were classified as nonasthmatics at the time of the last negative questionnaire. Modified Poisson regression analyses were used to estimate relative risks (RR) controlling for specific gravity and potential confounders. Of 300 children, 154 (51%) were examined by a physician because of reports of wheeze, other asthma-like symptoms, and/or medication use; 94 were diagnosed with current asthma and 60 without current asthma. The remaining 146 children were classified as nonasthmatic. Compared with levels in nonasthmatics, prenatal metabolites of BBzP and DnBP were associated with a history of asthma-like symptoms (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05) and with the diagnosis of current asthma: RR = 1.17 (95% CI: 1.01, 1.35) and RR = 1.25 (95% CI: 1.04, 1.51) per natural log-unit increase, respectively. Risk of current asthma was &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt; 70% higher among children with maternal prenatal BBzP and DnBP metabolite concentrations in the third versus the first tertile. Prenatal exposure to BBzP and DnBP may increase the risk of asthma among inner-city children. However, because this is the first such finding, results require replication.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="24555595"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="24555595"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 24555595; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=24555595]").text(description); $(".js-view-count[data-work-id=24555595]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 24555595; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='24555595']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 24555595, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=24555595]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":24555595,"title":"Asthma in Inner-City Children at 5-11 Years of Age and Prenatal Exposure to Phthalates: The Columbia Center for Children’s Environmental Health Cohort","translated_title":"","metadata":{"abstract":"Studies suggest that phthalate exposures may adversely affect child respiratory health. We evaluated associations between asthma diagnosed in children between 5 and 11 years of age and prenatal exposures to butylbenzyl phthalate (BBzP), di-n-butyl phthalate (DnBP), di(2-ethylhexyl) phthalate (DEHP), and diethyl phthalate (DEP). Phthalate metabolites were measured in spot urine collected from 300 pregnant inner-city women. Children were examined by an allergist or pulmonologist based on the first parental report of wheeze, other respiratory symptoms, and/or use of asthma rescue/controller medication in the preceding 12 months on repeat follow-up questionnaires. Standardized diagnostic criteria were used to classify these children as either having or not having current asthma at the time of the physician examination. Children without any report of wheeze or the other asthma-like symptoms were classified as nonasthmatics at the time of the last negative questionnaire. Modified Poisson regression analyses were used to estimate relative risks (RR) controlling for specific gravity and potential confounders. Of 300 children, 154 (51%) were examined by a physician because of reports of wheeze, other asthma-like symptoms, and/or medication use; 94 were diagnosed with current asthma and 60 without current asthma. The remaining 146 children were classified as nonasthmatic. Compared with levels in nonasthmatics, prenatal metabolites of BBzP and DnBP were associated with a history of asthma-like symptoms (p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05) and with the diagnosis of current asthma: RR = 1.17 (95% CI: 1.01, 1.35) and RR = 1.25 (95% CI: 1.04, 1.51) per natural log-unit increase, respectively. Risk of current asthma was \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt; 70% higher among children with maternal prenatal BBzP and DnBP metabolite concentrations in the third versus the first tertile. Prenatal exposure to BBzP and DnBP may increase the risk of asthma among inner-city children. However, because this is the first such finding, results require replication.","publication_date":{"day":null,"month":null,"year":2014,"errors":{}},"publication_name":"Environmental Health Perspectives"},"translated_abstract":"Studies suggest that phthalate exposures may adversely affect child respiratory health. We evaluated associations between asthma diagnosed in children between 5 and 11 years of age and prenatal exposures to butylbenzyl phthalate (BBzP), di-n-butyl phthalate (DnBP), di(2-ethylhexyl) phthalate (DEHP), and diethyl phthalate (DEP). Phthalate metabolites were measured in spot urine collected from 300 pregnant inner-city women. Children were examined by an allergist or pulmonologist based on the first parental report of wheeze, other respiratory symptoms, and/or use of asthma rescue/controller medication in the preceding 12 months on repeat follow-up questionnaires. Standardized diagnostic criteria were used to classify these children as either having or not having current asthma at the time of the physician examination. Children without any report of wheeze or the other asthma-like symptoms were classified as nonasthmatics at the time of the last negative questionnaire. Modified Poisson regression analyses were used to estimate relative risks (RR) controlling for specific gravity and potential confounders. Of 300 children, 154 (51%) were examined by a physician because of reports of wheeze, other asthma-like symptoms, and/or medication use; 94 were diagnosed with current asthma and 60 without current asthma. The remaining 146 children were classified as nonasthmatic. Compared with levels in nonasthmatics, prenatal metabolites of BBzP and DnBP were associated with a history of asthma-like symptoms (p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05) and with the diagnosis of current asthma: RR = 1.17 (95% CI: 1.01, 1.35) and RR = 1.25 (95% CI: 1.04, 1.51) per natural log-unit increase, respectively. Risk of current asthma was \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt; 70% higher among children with maternal prenatal BBzP and DnBP metabolite concentrations in the third versus the first tertile. Prenatal exposure to BBzP and DnBP may increase the risk of asthma among inner-city children. However, because this is the first such finding, results require replication.","internal_url":"https://www.academia.edu/24555595/Asthma_in_Inner_City_Children_at_5_11_Years_of_Age_and_Prenatal_Exposure_to_Phthalates_The_Columbia_Center_for_Children_s_Environmental_Health_Cohort","translated_internal_url":"","created_at":"2016-04-19T07:20:44.376-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":47333446,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":19203242,"work_id":24555595,"tagging_user_id":47333446,"tagged_user_id":null,"co_author_invite_id":128915,"email":"f***1@columbia.cdu","display_order":0,"name":"Frederica Perera","title":"Asthma in Inner-City Children at 5-11 Years of Age and Prenatal Exposure to Phthalates: The Columbia Center for Children’s Environmental Health Cohort"},{"id":19203283,"work_id":24555595,"tagging_user_id":47333446,"tagged_user_id":null,"co_author_invite_id":424338,"email":"r***5@columbia.edu","display_order":4194304,"name":"Robin Whyatt","title":"Asthma in Inner-City Children at 5-11 Years of Age and Prenatal Exposure to Phthalates: The Columbia Center for Children’s Environmental Health Cohort"},{"id":19203311,"work_id":24555595,"tagging_user_id":47333446,"tagged_user_id":289615080,"co_author_invite_id":150409,"email":"m***7@columbia.edu","display_order":6291456,"name":"Matthew Perzanowski","title":"Asthma in Inner-City Children at 5-11 Years of Age and Prenatal Exposure to Phthalates: The Columbia Center for Children’s Environmental Health Cohort"},{"id":19203339,"work_id":24555595,"tagging_user_id":47333446,"tagged_user_id":null,"co_author_invite_id":424349,"email":"k***8@columbia.edu","display_order":7340032,"name":"Kathleen Donohue","title":"Asthma in Inner-City Children at 5-11 Years of Age and Prenatal Exposure to Phthalates: The Columbia Center for Children’s Environmental Health Cohort"},{"id":19203378,"work_id":24555595,"tagging_user_id":47333446,"tagged_user_id":null,"co_author_invite_id":391570,"email":"a***t@hsph.harvard.edu","display_order":7864320,"name":"Allan Just","title":"Asthma in Inner-City Children at 5-11 Years of Age and Prenatal Exposure to Phthalates: The Columbia Center for Children’s Environmental Health Cohort"}],"downloadable_attachments":[],"slug":"Asthma_in_Inner_City_Children_at_5_11_Years_of_Age_and_Prenatal_Exposure_to_Phthalates_The_Columbia_Center_for_Children_s_Environmental_Health_Cohort","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":47333446,"first_name":"Lori","middle_initials":"","last_name":"Hoepner","page_name":"LHoepner","domain_name":"independent","created_at":"2016-04-19T07:19:51.045-07:00","display_name":"Lori Hoepner","url":"https://independent.academia.edu/LHoepner"},"attachments":[],"research_interests":[{"id":9968,"name":"Asthma","url":"https://www.academia.edu/Documents/in/Asthma"},{"id":22772,"name":"Urban Health","url":"https://www.academia.edu/Documents/in/Urban_Health"},{"id":58054,"name":"Environmental Sciences","url":"https://www.academia.edu/Documents/in/Environmental_Sciences"},{"id":62550,"name":"Pregnancy","url":"https://www.academia.edu/Documents/in/Pregnancy"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":248366,"name":"New York","url":"https://www.academia.edu/Documents/in/New_York"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":736321,"name":"Environmental Pollutants","url":"https://www.academia.edu/Documents/in/Environmental_Pollutants"},{"id":1312021,"name":"Environmental Exposure","url":"https://www.academia.edu/Documents/in/Environmental_Exposure"},{"id":1330083,"name":"Respiratory Sounds","url":"https://www.academia.edu/Documents/in/Respiratory_Sounds"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> </div><div class="profile--tab_content_container js-tab-pane tab-pane" data-section-id="5067495" id="papers"><div class="js-work-strip profile--work_container" data-work-id="20038907"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/20038907/Fractional_exhaled_nitric_oxide_exchange_parameters_among_9_year_old_inner_city_children"><img alt="Research paper thumbnail of Fractional exhaled nitric oxide exchange parameters among 9-year-old inner-city children" class="work-thumbnail" src="https://attachments.academia-assets.com/41261893/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/20038907/Fractional_exhaled_nitric_oxide_exchange_parameters_among_9_year_old_inner_city_children">Fractional exhaled nitric oxide exchange parameters among 9-year-old inner-city children</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://columbia.academia.edu/DiurkaDiaz">Diurka Diaz</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/LHoepner">Lori Hoepner</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://columbia.academia.edu/RachelMiller">Rachel Miller</a></span></div><div class="wp-workCard_item"><span>Pediatric Pulmonology</span><span>, 2011</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="ad1ba748c556e98872e0e63995a91310" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:41261893,&quot;asset_id&quot;:20038907,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/41261893/download_file?st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="20038907"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="20038907"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 20038907; 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We hypothesized that the flow independent NO parameters would be associated differentially with wheeze and seroatopy. Methods: As part of a birth cohort study, 9-year-old children (n ¼ 102) of African-American and Dominican mothers living in low-income NYC neighborhoods had FeNO samples collected offline at constant flow rates of 50, 83, and 100 ml/sec. Seroatopy was defined as having measurable (!0.35 IU/ml) specific IgE to any of the five inhalant indoor allergens tested. Current wheeze (last 12 months) was assessed by ISAAC questionnaire. Bronchial NO flux (J NO ) and alveolar NO concentration (C alv ) were estimated by the Pietropaoli and Hogman methods. Results: Valid exhalation flow rates were achieved in 96% of the children. Children with seroatopy (53%) had significantly higher median J NO (522 pl/sec vs. 161 pl/sec, P \u003c 0.001) when compared to nonseroatopic children; however, median C alv was not significantly different between these two groups (5.5 vs. 5.8, P ¼ 0.644). Children with wheeze in the past year (21.6%) had significantly higher median C alv (8.4 ppb vs. 4.9 ppb, P \u003c 0.001), but not J NO (295 pl/sec vs. 165 pl/sec, P ¼ 0.241) when compared with children without wheeze. These associations remained stable after adjustment for known confounders/covariates. Conclusions: The multiple flow method was easily implemented in this pediatric inner-city cohort. In this study population, alveolar concentration of NO may be a better indicator of current wheeze than single flow FeNO. Pediatr Pulmonol.","publication_date":{"day":null,"month":null,"year":2011,"errors":{}},"publication_name":"Pediatric Pulmonology","grobid_abstract_attachment_id":41261893},"translated_abstract":null,"internal_url":"https://www.academia.edu/20038907/Fractional_exhaled_nitric_oxide_exchange_parameters_among_9_year_old_inner_city_children","translated_internal_url":"","created_at":"2016-01-05T08:06:20.167-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":40977206,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":12589623,"work_id":20038907,"tagging_user_id":40977206,"tagged_user_id":null,"co_author_invite_id":2442935,"email":"f***1@pop-csm-vif.cc.columbia.edu","display_order":0,"name":"Frederica Perera","title":"Fractional exhaled nitric oxide exchange parameters among 9-year-old inner-city 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mothers with underweight, normal, and overweight prepregnancy BMI" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/24778234/Excessive_gestational_weight_gain_is_associated_with_long_term_body_fat_and_weight_retention_at_7_y_postpartum_in_African_American_and_Dominican_mothers_with_underweight_normal_and_overweight_prepregnancy_BMI">Excessive gestational weight gain is associated with long-term body fat and weight retention at 7 y postpartum in African American and Dominican mothers with underweight, normal, and overweight prepregnancy BMI</a></div><div class="wp-workCard_item"><span>The American journal of clinical nutrition</span><span>, Jan 21, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Excessive gestational weight gain (GWG) is associated with postpartum weight retention (PPWR) and...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Excessive gestational weight gain (GWG) is associated with postpartum weight retention (PPWR) and abdominal adiposity, but long-term effects are understudied in low-income and minority populations at high risk of obesity and associated sequelae. We examined associations between GWG and long-term PPWR and adiposity in a prospective cohort of African American and Dominican mothers in the Bronx and Northern Manhattan. Women (n = 302) were enrolled during pregnancy and were followed for 7 y postpartum. Linear regression was used to relate excessive GWG [greater than 2009 Institute of Medicine (IOM) guidelines] to outcomes [percentage body fat and long-term PPWR (change in weight from prepregnancy to 7 y postpartum)], adjusting for covariates and included an interaction term between prepregnancy body mass index (BMI; in kg/m(2)) and GWG. Mean ± SD prepregnancy BMI and total GWG were 25.6 ± 5.8 (42% of women had BMI ≥25) and 16.6 ± 7.8 kg (64% of women had total GWG greater than IOM guide...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="24778234"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="24778234"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 24778234; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=24778234]").text(description); $(".js-view-count[data-work-id=24778234]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 24778234; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='24778234']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 24778234, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=24778234]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":24778234,"title":"Excessive gestational weight gain is associated with long-term body fat and weight retention at 7 y postpartum in African American and Dominican mothers with underweight, normal, and overweight prepregnancy BMI","translated_title":"","metadata":{"abstract":"Excessive gestational weight gain (GWG) is associated with postpartum weight retention (PPWR) and abdominal adiposity, but long-term effects are understudied in low-income and minority populations at high risk of obesity and associated sequelae. We examined associations between GWG and long-term PPWR and adiposity in a prospective cohort of African American and Dominican mothers in the Bronx and Northern Manhattan. Women (n = 302) were enrolled during pregnancy and were followed for 7 y postpartum. Linear regression was used to relate excessive GWG [greater than 2009 Institute of Medicine (IOM) guidelines] to outcomes [percentage body fat and long-term PPWR (change in weight from prepregnancy to 7 y postpartum)], adjusting for covariates and included an interaction term between prepregnancy body mass index (BMI; in kg/m(2)) and GWG. Mean ± SD prepregnancy BMI and total GWG were 25.6 ± 5.8 (42% of women had BMI ≥25) and 16.6 ± 7.8 kg (64% of women had total GWG greater than IOM guide...","publication_date":{"day":21,"month":1,"year":2015,"errors":{}},"publication_name":"The American journal of clinical nutrition"},"translated_abstract":"Excessive gestational weight gain (GWG) is associated with postpartum weight retention (PPWR) and abdominal adiposity, but long-term effects are understudied in low-income and minority populations at high risk of obesity and associated sequelae. We examined associations between GWG and long-term PPWR and adiposity in a prospective cohort of African American and Dominican mothers in the Bronx and Northern Manhattan. Women (n = 302) were enrolled during pregnancy and were followed for 7 y postpartum. Linear regression was used to relate excessive GWG [greater than 2009 Institute of Medicine (IOM) guidelines] to outcomes [percentage body fat and long-term PPWR (change in weight from prepregnancy to 7 y postpartum)], adjusting for covariates and included an interaction term between prepregnancy body mass index (BMI; in kg/m(2)) and GWG. Mean ± SD prepregnancy BMI and total GWG were 25.6 ± 5.8 (42% of women had BMI ≥25) and 16.6 ± 7.8 kg (64% of women had total GWG greater than IOM guide...","internal_url":"https://www.academia.edu/24778234/Excessive_gestational_weight_gain_is_associated_with_long_term_body_fat_and_weight_retention_at_7_y_postpartum_in_African_American_and_Dominican_mothers_with_underweight_normal_and_overweight_prepregnancy_BMI","translated_internal_url":"","created_at":"2016-04-26T09:50:53.711-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":47333446,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Excessive_gestational_weight_gain_is_associated_with_long_term_body_fat_and_weight_retention_at_7_y_postpartum_in_African_American_and_Dominican_mothers_with_underweight_normal_and_overweight_prepregnancy_BMI","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":47333446,"first_name":"Lori","middle_initials":"","last_name":"Hoepner","page_name":"LHoepner","domain_name":"independent","created_at":"2016-04-19T07:19:51.045-07:00","display_name":"Lori Hoepner","url":"https://independent.academia.edu/LHoepner"},"attachments":[],"research_interests":[{"id":48,"name":"Engineering","url":"https://www.academia.edu/Documents/in/Engineering"},{"id":2808,"name":"Poverty","url":"https://www.academia.edu/Documents/in/Poverty"},{"id":8207,"name":"Risk","url":"https://www.academia.edu/Documents/in/Risk"},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent"},{"id":44962,"name":"Dominican Republic","url":"https://www.academia.edu/Documents/in/Dominican_Republic"},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies"},{"id":62550,"name":"Pregnancy","url":"https://www.academia.edu/Documents/in/Pregnancy"},{"id":63375,"name":"Overweight","url":"https://www.academia.edu/Documents/in/Overweight"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":87786,"name":"New York City","url":"https://www.academia.edu/Documents/in/New_York_City"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult"},{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies"},{"id":192564,"name":"Body Mass Index","url":"https://www.academia.edu/Documents/in/Body_Mass_Index"},{"id":233800,"name":"African Americans","url":"https://www.academia.edu/Documents/in/African_Americans"},{"id":234187,"name":"Recurrence","url":"https://www.academia.edu/Documents/in/Recurrence"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":543452,"name":"Thinness","url":"https://www.academia.edu/Documents/in/Thinness"},{"id":1141692,"name":"Weight Gain","url":"https://www.academia.edu/Documents/in/Weight_Gain"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="24778233"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/24778233/Community_based_focus_groups_guide_epistemological_change_to_educational_materials_at_Columbia_Center_for_Childrens_Environmental_Health"><img alt="Research paper thumbnail of Community-based focus groups guide epistemological change to educational materials at Columbia Center for Children&#39;s Environmental Health" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/24778233/Community_based_focus_groups_guide_epistemological_change_to_educational_materials_at_Columbia_Center_for_Childrens_Environmental_Health">Community-based focus groups guide epistemological change to educational materials at Columbia Center for Children&#39;s Environmental Health</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">BACKGROUND: Environmental exposures during pregnancy and early childhood can lead to adverse outc...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">BACKGROUND: Environmental exposures during pregnancy and early childhood can lead to adverse outcomes in child development. The Columbia Center for Children’s Environmental Health (CCCEH) has linked bisphenol-A (BPA) exposures to anxiety, depressive mood, attention problems and asthma in children. OBJECTIVE: CCCEH’s Community Outreach &amp;Translation Core (COTC) developed an educational brochure showing ways to reduce BPA exposure, using focus groups to ensure materials were culturally relevant for low-income communities of color in Northern Manhattan and South Bronx. METHODS: Three focus groups with women of childbearing age were conducted in English (n= 16) and Spanish (n= 8) using a discussion guide developed with the CCCEH Community Advisory and Stakeholders Board (CASB). Participants were recruited through community-based organizations that serve on CCCEH&amp;#39;s CASB. We discussed participants’ knowledge, beliefs, and health behaviors related to environmental health and BPA. Respon...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="24778233"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="24778233"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 24778233; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=24778233]").text(description); $(".js-view-count[data-work-id=24778233]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 24778233; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='24778233']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 24778233, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=24778233]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":24778233,"title":"Community-based focus groups guide epistemological change to educational materials at Columbia Center for Children's Environmental Health","translated_title":"","metadata":{"abstract":"BACKGROUND: Environmental exposures during pregnancy and early childhood can lead to adverse outcomes in child development. The Columbia Center for Children’s Environmental Health (CCCEH) has linked bisphenol-A (BPA) exposures to anxiety, depressive mood, attention problems and asthma in children. OBJECTIVE: CCCEH’s Community Outreach \u0026Translation Core (COTC) developed an educational brochure showing ways to reduce BPA exposure, using focus groups to ensure materials were culturally relevant for low-income communities of color in Northern Manhattan and South Bronx. METHODS: Three focus groups with women of childbearing age were conducted in English (n= 16) and Spanish (n= 8) using a discussion guide developed with the CCCEH Community Advisory and Stakeholders Board (CASB). Participants were recruited through community-based organizations that serve on CCCEH\u0026#39;s CASB. We discussed participants’ knowledge, beliefs, and health behaviors related to environmental health and BPA. Respon..."},"translated_abstract":"BACKGROUND: Environmental exposures during pregnancy and early childhood can lead to adverse outcomes in child development. The Columbia Center for Children’s Environmental Health (CCCEH) has linked bisphenol-A (BPA) exposures to anxiety, depressive mood, attention problems and asthma in children. OBJECTIVE: CCCEH’s Community Outreach \u0026Translation Core (COTC) developed an educational brochure showing ways to reduce BPA exposure, using focus groups to ensure materials were culturally relevant for low-income communities of color in Northern Manhattan and South Bronx. METHODS: Three focus groups with women of childbearing age were conducted in English (n= 16) and Spanish (n= 8) using a discussion guide developed with the CCCEH Community Advisory and Stakeholders Board (CASB). Participants were recruited through community-based organizations that serve on CCCEH\u0026#39;s CASB. We discussed participants’ knowledge, beliefs, and health behaviors related to environmental health and BPA. Respon...","internal_url":"https://www.academia.edu/24778233/Community_based_focus_groups_guide_epistemological_change_to_educational_materials_at_Columbia_Center_for_Childrens_Environmental_Health","translated_internal_url":"","created_at":"2016-04-26T09:50:53.601-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":47333446,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Community_based_focus_groups_guide_epistemological_change_to_educational_materials_at_Columbia_Center_for_Childrens_Environmental_Health","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":47333446,"first_name":"Lori","middle_initials":"","last_name":"Hoepner","page_name":"LHoepner","domain_name":"independent","created_at":"2016-04-19T07:19:51.045-07:00","display_name":"Lori Hoepner","url":"https://independent.academia.edu/LHoepner"},"attachments":[],"research_interests":[],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="24778232"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/24778232/Prenatal_Exposure_to_Phthalates_and_Childhood_Body_Size_in_an_Urban_Cohort"><img alt="Research paper thumbnail of Prenatal Exposure to Phthalates and Childhood Body Size in an Urban Cohort" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/24778232/Prenatal_Exposure_to_Phthalates_and_Childhood_Body_Size_in_an_Urban_Cohort">Prenatal Exposure to Phthalates and Childhood Body Size in an Urban Cohort</a></div><div class="wp-workCard_item"><span>Environmental health perspectives</span><span>, Jan 12, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Phthalate exposures are hypothesized to increase obesity; however, prior research has been largel...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Phthalate exposures are hypothesized to increase obesity; however, prior research has been largely cross-sectional. To evaluate associations between prenatal phthalate exposures and body mass index (BMI) at child ages 5 and 7 years. Nine metabolites of six phthalates: di-(2-ethylhexyl) phthalate (DEHP), di-n-octyl-, di-iso-butyl-, di-n-butyl-, butylbenzyl-, and diethyl phthalates, were measured in spot urine samples collected from pregnant African American and Dominican women during their third trimester, and from their children at ages 3 and 5 years. To reduce multiple comparison issues, we initially used Principal Component Analysis (PCA) to identify major patterns of (ln)-transformed metabolite concentrations. Height and weight were assessed at ages 5 and 7 years, and fat mass and waist circumference at age 7. Linearized generalized estimating equation analyses related maternal component scores to child anthropometric outcomes at ages 5 (n=326) and 7 (n=330). PCA identified a DEH...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="24778232"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="24778232"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 24778232; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=24778232]").text(description); $(".js-view-count[data-work-id=24778232]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 24778232; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='24778232']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 24778232, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=24778232]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":24778232,"title":"Prenatal Exposure to Phthalates and Childhood Body Size in an Urban Cohort","translated_title":"","metadata":{"abstract":"Phthalate exposures are hypothesized to increase obesity; however, prior research has been largely cross-sectional. 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PCA identified a DEH...","publication_date":{"day":12,"month":1,"year":2015,"errors":{}},"publication_name":"Environmental health perspectives"},"translated_abstract":"Phthalate exposures are hypothesized to increase obesity; however, prior research has been largely cross-sectional. To evaluate associations between prenatal phthalate exposures and body mass index (BMI) at child ages 5 and 7 years. Nine metabolites of six phthalates: di-(2-ethylhexyl) phthalate (DEHP), di-n-octyl-, di-iso-butyl-, di-n-butyl-, butylbenzyl-, and diethyl phthalates, were measured in spot urine samples collected from pregnant African American and Dominican women during their third trimester, and from their children at ages 3 and 5 years. To reduce multiple comparison issues, we initially used Principal Component Analysis (PCA) to identify major patterns of (ln)-transformed metabolite concentrations. Height and weight were assessed at ages 5 and 7 years, and fat mass and waist circumference at age 7. Linearized generalized estimating equation analyses related maternal component scores to child anthropometric outcomes at ages 5 (n=326) and 7 (n=330). PCA identified a DEH...","internal_url":"https://www.academia.edu/24778232/Prenatal_Exposure_to_Phthalates_and_Childhood_Body_Size_in_an_Urban_Cohort","translated_internal_url":"","created_at":"2016-04-26T09:50:53.488-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":47333446,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Prenatal_Exposure_to_Phthalates_and_Childhood_Body_Size_in_an_Urban_Cohort","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":47333446,"first_name":"Lori","middle_initials":"","last_name":"Hoepner","page_name":"LHoepner","domain_name":"independent","created_at":"2016-04-19T07:19:51.045-07:00","display_name":"Lori Hoepner","url":"https://independent.academia.edu/LHoepner"},"attachments":[],"research_interests":[{"id":58054,"name":"Environmental Sciences","url":"https://www.academia.edu/Documents/in/Environmental_Sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="24778231"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/24778231/Gestational_weight_gain_and_obesity_adiposity_and_body_size_in_African_American_and_Dominican_children_in_the_Bronx_and_Northern_Manhattan"><img alt="Research paper thumbnail of Gestational weight gain and obesity, adiposity and body size in African-American and Dominican children in the Bronx and Northern Manhattan" class="work-thumbnail" src="https://attachments.academia-assets.com/45106270/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/24778231/Gestational_weight_gain_and_obesity_adiposity_and_body_size_in_African_American_and_Dominican_children_in_the_Bronx_and_Northern_Manhattan">Gestational weight gain and obesity, adiposity and body size in African-American and Dominican children in the Bronx and Northern Manhattan</a></div><div class="wp-workCard_item"><span>Maternal &amp; Child Nutrition</span><span>, 2015</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="06e05b8ff008a0f74df23cc632b0fa25" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:45106270,&quot;asset_id&quot;:24778231,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/45106270/download_file?st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="24778231"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="24778231"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 24778231; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=24778231]").text(description); $(".js-view-count[data-work-id=24778231]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 24778231; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='24778231']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 24778231, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); 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We examined the association between GWG and child anthropometric measures and body composition at 7 years [waist circumference (WC), body mass index z-score (BMIZ), obesity (BMIZ ≥95%ile) and bioelectrical impedance analysis estimates of percentage body fat (%fat)] in African-American and Dominican dyads (n = 323) in the Columbia Center for Children's Environmental Health prospective birth cohort study from 1998 to 2013. Linear and logistic regression evaluated associations between excessive GWG [\u003eInstitute of Medicine (IOM) 2009 guidelines] and outcomes, adjusting for pre-pregnancy BMI and covariates. Pre-pregnancy BMI (mean ± standard deviation, all such values) and total GWG were 25.8 ± 6.2 kg m −2 (45% overweight/ obese) and 16.4 ± 7.9 kg (64% \u003e IOM guidelines), respectively. Excessive GWG was associated with higher BMIZ {0.44 [95% confidence interval (CI): 0.2, 0.7], P \u003c 0.001}, WC [β: 2.9 cm (95% CI: 1.1, 4.6), P = 0.002], %fat at 7 years [β: 2.2% (95% CI: 1.0, 3.5), P = 0.001)] and obesity [odds ratio: 2.93 (95% CI: 1.5, 5.8), P = 0.002]. Pre-pregnancy BMI was positively associated with child size, adiposity and obesity (all P \u003c 0.05). Excessive GWG was highly prevalent and was associated with child obesity, greater percentage body fat and abdominal adiposity. Strategies to support healthy GWG are warranted to promote healthy growth and prevent childhood obesity.","publication_date":{"day":null,"month":null,"year":2015,"errors":{}},"publication_name":"Maternal \u0026 Child Nutrition","grobid_abstract_attachment_id":45106270},"translated_abstract":null,"internal_url":"https://www.academia.edu/24778231/Gestational_weight_gain_and_obesity_adiposity_and_body_size_in_African_American_and_Dominican_children_in_the_Bronx_and_Northern_Manhattan","translated_internal_url":"","created_at":"2016-04-26T09:50:53.389-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":47333446,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":45106270,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/45106270/thumbnails/1.jpg","file_name":"Gestational_weight_gain_and_obesity_adip20160426-7877-1lylm2r.pdf","download_url":"https://www.academia.edu/attachments/45106270/download_file?st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Gestational_weight_gain_and_obesity_adip.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/45106270/Gestational_weight_gain_and_obesity_adip20160426-7877-1lylm2r-libre.pdf?1461689793=\u0026response-content-disposition=attachment%3B+filename%3DGestational_weight_gain_and_obesity_adip.pdf\u0026Expires=1732420691\u0026Signature=Zv-2TV-7A4~qvkCPUzF1~vIE-yZPE0T1qVu1dhZSmZ0eUATsmg-S4LLiPqSkRp9owMOFIexf2fmWhxdsAbFpucFqrQXo9ks7llXZ9brG8pkY16ERO8dsomALnucpPrBnnhu4XPoVR~9CqzVFjGc1T4~60rErgBtyhzlQX7U7~BRr0uwZDl7WHlx8j6sHa6Cp0q0u7svQtr1ktV3vUtNHqGGLa9KJWed0iQ9YalT~B57AeBfQTIWBa1DceSOHXv6lTJlGA7YaBsKpzLR0ZNoYOXNnT08tRIAqtboZPszALNmRt6axUr01bqQKWnfdEOtrtC6~eAd5P4ICkgbdSlQn4A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Gestational_weight_gain_and_obesity_adiposity_and_body_size_in_African_American_and_Dominican_children_in_the_Bronx_and_Northern_Manhattan","translated_slug":"","page_count":11,"language":"en","content_type":"Work","owner":{"id":47333446,"first_name":"Lori","middle_initials":"","last_name":"Hoepner","page_name":"LHoepner","domain_name":"independent","created_at":"2016-04-19T07:19:51.045-07:00","display_name":"Lori Hoepner","url":"https://independent.academia.edu/LHoepner"},"attachments":[{"id":45106270,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/45106270/thumbnails/1.jpg","file_name":"Gestational_weight_gain_and_obesity_adip20160426-7877-1lylm2r.pdf","download_url":"https://www.academia.edu/attachments/45106270/download_file?st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Gestational_weight_gain_and_obesity_adip.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/45106270/Gestational_weight_gain_and_obesity_adip20160426-7877-1lylm2r-libre.pdf?1461689793=\u0026response-content-disposition=attachment%3B+filename%3DGestational_weight_gain_and_obesity_adip.pdf\u0026Expires=1732420691\u0026Signature=Zv-2TV-7A4~qvkCPUzF1~vIE-yZPE0T1qVu1dhZSmZ0eUATsmg-S4LLiPqSkRp9owMOFIexf2fmWhxdsAbFpucFqrQXo9ks7llXZ9brG8pkY16ERO8dsomALnucpPrBnnhu4XPoVR~9CqzVFjGc1T4~60rErgBtyhzlQX7U7~BRr0uwZDl7WHlx8j6sHa6Cp0q0u7svQtr1ktV3vUtNHqGGLa9KJWed0iQ9YalT~B57AeBfQTIWBa1DceSOHXv6lTJlGA7YaBsKpzLR0ZNoYOXNnT08tRIAqtboZPszALNmRt6axUr01bqQKWnfdEOtrtC6~eAd5P4ICkgbdSlQn4A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":591,"name":"Nutrition and Dietetics","url":"https://www.academia.edu/Documents/in/Nutrition_and_Dietetics"},{"id":38359,"name":"Maternal and Child Nutrition","url":"https://www.academia.edu/Documents/in/Maternal_and_Child_Nutrition"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="24778230"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/24778230/Preliminary_Findings_from_the_New_York_City_Neighborhood_Asthma_and_Allergy_Study"><img alt="Research paper thumbnail of Preliminary Findings from the New York City Neighborhood Asthma and Allergy Study" class="work-thumbnail" src="https://attachments.academia-assets.com/45106271/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/24778230/Preliminary_Findings_from_the_New_York_City_Neighborhood_Asthma_and_Allergy_Study">Preliminary Findings from the New York City Neighborhood Asthma and Allergy Study</a></div><div class="wp-workCard_item"><span>Journal of Allergy and Clinical Immunology</span><span>, 2009</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="2d563f13e99a5664f871823d7bbf914c" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:45106271,&quot;asset_id&quot;:24778230,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/45106271/download_file?st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="24778230"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="24778230"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 24778230; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=24778230]").text(description); $(".js-view-count[data-work-id=24778230]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 24778230; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='24778230']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 24778230, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "2d563f13e99a5664f871823d7bbf914c" } } $('.js-work-strip[data-work-id=24778230]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":24778230,"title":"Preliminary Findings from the New York City Neighborhood Asthma and Allergy Study","translated_title":"","metadata":{"grobid_abstract":"RATIONALE: Since traditional farming represents a unique model situation to investigate the relationship of early-life microbial exposure and allergy protection. associations between maternal farming exposures and cytokine production in cord blood mononuclear cells in a prospective multi-national birth cohort of 530 farm and 603 non-farm children and their families. METHODS: Supernatants from stimulated CB mononuclear cells were assessed for the production of IL-5, IFN-g, IL-10 IL-12 and TNF-a by using ELISA-assays. Associations between maternal farming exposures and the porduction of cord blood cytokines were assessed by using a Tobit-regression model. RESULTS: Cord blood from farmer children showed significantly higher levels of TNF-a and IFN-g production compared to cord blood non-farmer children, whereas IL-10, IL-12 and IL-5 levels did not differ between these study groups. Elevated TNF-a and IFN-g levels in cord blood were associated with maternal exposures to farm animals, animal sheds, hay lofts, farm milk and farm milk products during pregnancy. CONCLUSIONS: Maternal exposure to farming activities and farm products during pregnancy modulated cytokine production patterns of their offspring at birth.","publication_date":{"day":null,"month":null,"year":2009,"errors":{}},"publication_name":"Journal of Allergy and Clinical Immunology","grobid_abstract_attachment_id":45106271},"translated_abstract":null,"internal_url":"https://www.academia.edu/24778230/Preliminary_Findings_from_the_New_York_City_Neighborhood_Asthma_and_Allergy_Study","translated_internal_url":"","created_at":"2016-04-26T09:50:53.286-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":47333446,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":45106271,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/45106271/thumbnails/1.jpg","file_name":"j.jaci.2008.12.093.pdf20160426-12263-1g2ynft","download_url":"https://www.academia.edu/attachments/45106271/download_file?st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Preliminary_Findings_from_the_New_York_C.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/45106271/j.jaci.2008.12.093-libre.pdf20160426-12263-1g2ynft?1461689792=\u0026response-content-disposition=attachment%3B+filename%3DPreliminary_Findings_from_the_New_York_C.pdf\u0026Expires=1732420691\u0026Signature=R1PBf0Y4YBYZx6PHh39h-opOxGtTBZGLgg3XN1bvxVi98kYEU~Sipm1EJ1fitcQSX3xLLirI06IgjQ2OV36dEjoaZSifn8xu5dscj9FIwg~iw6oLD-871HGW-APGLguKLLmhLsepJK-2UUXhXBFbLIOCziIzGlr5~~utUTfp~neVOiHeQLV9Vld7urqEXIFm9yGtpaFRJ5htruwiH3Y2V6LV4DEHyR49PZG5NPpN~emEoVckqzvECB7Zhz2xnqAC2VfdWztdfgHMSRUB50D~~UFLn39rCRJh1Mkv4DXMwbAKz2F1EXPmHFLzg7kaoIlObh~-ZTiSMvOdsCcTreaJxg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Preliminary_Findings_from_the_New_York_City_Neighborhood_Asthma_and_Allergy_Study","translated_slug":"","page_count":1,"language":"en","content_type":"Work","owner":{"id":47333446,"first_name":"Lori","middle_initials":"","last_name":"Hoepner","page_name":"LHoepner","domain_name":"independent","created_at":"2016-04-19T07:19:51.045-07:00","display_name":"Lori 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York City","url":"https://www.academia.edu/Documents/in/New_York_City"},{"id":1826493,"name":"Clinical Allergy and Immunology","url":"https://www.academia.edu/Documents/in/Clinical_Allergy_and_Immunology"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="24778229"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/24778229/Abstract_LB_402_Chromosomal_aberrations_in_5_year_olds_and_urinary_PAH_metabolites"><img alt="Research paper thumbnail of Abstract LB-402: Chromosomal aberrations in 5-year olds and urinary PAH metabolites" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div 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class="js-work-strip profile--work_container" data-work-id="24561060"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/24561060/HIV_prevention_with_severely_mentally_ill_men_A_randomised_controlled_trial"><img alt="Research paper thumbnail of HIV prevention with severely mentally ill men: A randomised controlled trial" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/24561060/HIV_prevention_with_severely_mentally_ill_men_A_randomised_controlled_trial">HIV prevention with severely mentally ill men: A randomised controlled trial</a></div><div class="wp-workCard_item"><span>AIDS Care</span><span>, 2007</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">We conducted a randomised clinical trial to test the efficacy of an enhanced version of an interv...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">We conducted a randomised clinical trial to test the efficacy of an enhanced version of an intervention previously shown to reduce HIV sexual risk behaviours among men with severe mental illness. One-hundred-and-forty-nine subjects aged 18-59 years were randomly assigned to the experimental or control conditions. Sexual risk behaviours were assessed every three months for 12-months. The primary analysis compared experimental and control groups with respect to sexual risk behaviours with casual partners as measured by the Vaginal Episodes Equivalent (VEE) score. Additional analyses included comparison of VEE scores of those men sexually active in the three months prior to baseline and the proportion of condom-protected sexual acts with casual partners. There were no significant differences in sexual risk behaviours with casual partners between experimental and control subjects. Additional analyses demonstrated a trend toward sexual risk reduction at six months post-intervention (p=0.06) but not at 12 months. These results may reflect a lack of efficacy or a true reduction in risk that the trial was underpowered to detect at the 0.05-level. If there was a true reduction in risk, it was not maintained after the initial six months.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="24561060"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="24561060"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 24561060; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=24561060]").text(description); $(".js-view-count[data-work-id=24561060]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 24561060; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='24561060']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 24561060, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=24561060]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":24561060,"title":"HIV prevention with severely mentally ill men: A randomised controlled trial","translated_title":"","metadata":{"abstract":"We conducted a randomised clinical trial to test the efficacy of an enhanced version of an intervention previously shown to reduce HIV sexual risk behaviours among men with severe mental illness. One-hundred-and-forty-nine subjects aged 18-59 years were randomly assigned to the experimental or control conditions. Sexual risk behaviours were assessed every three months for 12-months. The primary analysis compared experimental and control groups with respect to sexual risk behaviours with casual partners as measured by the Vaginal Episodes Equivalent (VEE) score. Additional analyses included comparison of VEE scores of those men sexually active in the three months prior to baseline and the proportion of condom-protected sexual acts with casual partners. There were no significant differences in sexual risk behaviours with casual partners between experimental and control subjects. Additional analyses demonstrated a trend toward sexual risk reduction at six months post-intervention (p=0.06) but not at 12 months. These results may reflect a lack of efficacy or a true reduction in risk that the trial was underpowered to detect at the 0.05-level. If there was a true reduction in risk, it was not maintained after the initial six months.","publication_date":{"day":null,"month":null,"year":2007,"errors":{}},"publication_name":"AIDS Care"},"translated_abstract":"We conducted a randomised clinical trial to test the efficacy of an enhanced version of an intervention previously shown to reduce HIV sexual risk behaviours among men with severe mental illness. One-hundred-and-forty-nine subjects aged 18-59 years were randomly assigned to the experimental or control conditions. Sexual risk behaviours were assessed every three months for 12-months. The primary analysis compared experimental and control groups with respect to sexual risk behaviours with casual partners as measured by the Vaginal Episodes Equivalent (VEE) score. Additional analyses included comparison of VEE scores of those men sexually active in the three months prior to baseline and the proportion of condom-protected sexual acts with casual partners. There were no significant differences in sexual risk behaviours with casual partners between experimental and control subjects. Additional analyses demonstrated a trend toward sexual risk reduction at six months post-intervention (p=0.06) but not at 12 months. These results may reflect a lack of efficacy or a true reduction in risk that the trial was underpowered to detect at the 0.05-level. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="12494661"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/12494661/1_Effects_of_Season_and_Indoor_Heating_on_Indoor_and_Outdoor_Residential_Levels_of_Airborne_Polycyclic_Aromatic_Hydrocarbons_Absorbance_and_Particulate_Matter_2_5_in_an_Inner_City_Cohort_of_Young_Children"><img alt="Research paper thumbnail of 1. Effects of Season and Indoor Heating on Indoor and Outdoor Residential Levels of Airborne Polycyclic Aromatic Hydrocarbons, Absorbance and Particulate Matter 2.5 in an Inner City Cohort of Young Children" class="work-thumbnail" src="https://attachments.academia-assets.com/46143567/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/12494661/1_Effects_of_Season_and_Indoor_Heating_on_Indoor_and_Outdoor_Residential_Levels_of_Airborne_Polycyclic_Aromatic_Hydrocarbons_Absorbance_and_Particulate_Matter_2_5_in_an_Inner_City_Cohort_of_Young_Children">1. Effects of Season and Indoor Heating on Indoor and Outdoor Residential Levels of Airborne Polycyclic Aromatic Hydrocarbons, Absorbance and Particulate Matter 2.5 in an Inner City Cohort of Young Children</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/LHoepner">Lori Hoepner</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/StevenChillrud">Steven Chillrud</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/DavidCamann">David Camann</a></span></div><div class="wp-workCard_item"><span>Journal of Allergy and Clinical Immunology</span><span>, 2010</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="65cf1f2a1d508219364e37592d6f600c" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:46143567,&quot;asset_id&quot;:12494661,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/46143567/download_file?st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="12494661"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="12494661"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 12494661; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=12494661]").text(description); $(".js-view-count[data-work-id=12494661]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 12494661; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='12494661']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 12494661, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "65cf1f2a1d508219364e37592d6f600c" } } $('.js-work-strip[data-work-id=12494661]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":12494661,"title":"1. Effects of Season and Indoor Heating on Indoor and Outdoor Residential Levels of Airborne Polycyclic Aromatic Hydrocarbons, Absorbance and Particulate Matter 2.5 in an Inner City Cohort of Young Children","translated_title":"","metadata":{"grobid_abstract":"RATIONALE: Freshwater and marine cyanobacteria and dinoflagelates are known to elaborate toxins which induce inflammatory rashes and cough in exposed swimmers. The immune mechanism of inflammatory reactions is unknown but clinical symptoms such as erythematous pruritic rashes are common. We used purified marine toxins; debromaplysiatoxins, lyngbyatoxin-a, saxitoxin, and brevatoxin to determine induction of immune activation of human cells ex vivo. METHODS: Meyelomonocytic (U937) cell lines, T-cell (Jurkat) lines, and peripheral mononuclear cells (PBMC) were exposed to the panel of aquatic toxins with lipopolysacchride (LPS) serving as a positive control. Assessment of cell viability and cell cycle analysis was performed using propidium idodide. Elaboration of pro-inflammatory cytokine production by cells cultured with toxins for 48 hours were measured using flow cytometry-based cytokine bead arrays. RESULTS: Toxin concentrations were selected that did not induce cell death. Lyngbyatoxin-a induced G0 cell cycle arrest in U937 cells. When compared to media alone PBMCs exposed to Lyngbyatoxin-a produced significant levels of TNFa, IL-6, IL-1B, IL-10, IL-4, and IL-5 but had no effect on INFg or IL-12 production. The magnitude was similar to PBMC incubated with LPS. None of the other marine toxins tested induced cytokine production by PBMC. CONCLUSIONS: Lyngbyatoxin-a induces macrophage derived pro-inflammatory cytokines and monocyte differentiation ex vivo. The cytokine pattern suggests that it may be mediated through TLR-4 binding. In addition, high levels of the TH2 cytokines IL-4 and IL-5 indicate that these cytokines modulate a TH2 immune response potentially explaining the clinical manifestations seen in individuals following exposure.","publication_date":{"day":null,"month":null,"year":2010,"errors":{}},"publication_name":"Journal of Allergy and Clinical Immunology","grobid_abstract_attachment_id":46143567},"translated_abstract":null,"internal_url":"https://www.academia.edu/12494661/1_Effects_of_Season_and_Indoor_Heating_on_Indoor_and_Outdoor_Residential_Levels_of_Airborne_Polycyclic_Aromatic_Hydrocarbons_Absorbance_and_Particulate_Matter_2_5_in_an_Inner_City_Cohort_of_Young_Children","translated_internal_url":"","created_at":"2015-05-20T13:22:18.039-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":31351195,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":17339963,"work_id":12494661,"tagging_user_id":31351195,"tagged_user_id":47333446,"co_author_invite_id":396777,"email":"l***5@columbia.edu","display_order":0,"name":"Lori Hoepner","title":"1. 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Methods: Mono-n-butyl phthalate (MnBP), monobenzyl phthalate (MBzP), monoisobutyl phthalate (MiBP), and four di-2-ethylhexyl phthalate metabolites were measured in a spot urine sample collected from 319 women during the third trimester. When children were 3 years of age, the Mental Development Index (MDI) and Psychomotor Development Index (PDI) were measured using the Bayley Scales of Infant Development II, and behavior problems were assessed by maternal report on the Child Behavior Checklist. results: Child PDI scores decreased with increasing log e MnBP [estimated adjusted β-coefficient = -2.81; 95% confidence interval (CI): -4.63, -1.0] and log e MiBP (β = -2.28; 95% CI: -3.90, -0.67); odds of motor delay increased significantly [per log e MnBP: estimated adjusted odds ratio (OR) = 1.64; 95% CI: 1.10, 2.44; per log e MiBP: adjusted OR =1.82; 95% CI: 1.24, 2.66]. In girls, MDI scores decreased with increasing log e MnBP (β = -2.67; 95% CI: -4.70, -0.65); the child sex difference in odds of mental delay was significant (p = 0.037). The ORs for clinically withdrawn behavior were 2.23 (95% CI: 1.27, 3.92) and 1.57 (95% CI: 1.07, 2.31) per log e unit increase in MnBP and MBzP, respectively; for clinically internalizing behaviors, the OR was 1.43 (95% CI: 1.01, 1.90) per log e unit increase in MBzP. Significant child sex differences were seen in associations between MnBP and MBzP and behaviors in internalizing domains (p \u003c 0.05). conclusion: Certain prenatal phthalate exposures may decrease child mental and motor development and increase internalizing behaviors. key words: behavior, child, mental, phthalates, prenatal, psychomotor. 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wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/24555600/Prenatal_exposure_to_antibiotics_cesarean_section_and_risk_of_childhood_obesity">Prenatal exposure to antibiotics, cesarean section and risk of childhood obesity</a></div><div class="wp-workCard_item"><span>International journal of obesity (2005)</span><span>, Jan 11, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background/Objectives:Cesarean section (CS) and antibiotic use during pregnancy may alter normal ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background/Objectives:Cesarean section (CS) and antibiotic use during pregnancy may alter normal maternal-offspring microbiota exchange, thereby contributing to aberrant microbial colonization of the infant gut and increased susceptibility to obesity later in life. We hypothesized that (i) maternal use of antibiotics in the second or third trimester of pregnancy and (ii) CS are independently associated with higher risk of childhood obesity in the offspring.Subjects/Methods:Of the 727 mothers enrolled in the Northern Manhattan Mothers and Children Study, we analyzed the 436 mother-child dyads followed until 7 years of age with complete data. We ascertained prenatal antibiotic use by a questionnaire administered late in the third trimester, and delivery mode by medical record. We derived age- and sex-specific body mass index (BMI) z-scores using the CDC SAS Macro, and defined obesity as BMI z⩾95th percentile. We used binary regression with robust variance and linear regression models ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="362de751ca033778bcf9e2fa47f3ae69" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{&quot;attachment_id&quot;:44885809,&quot;asset_id&quot;:24555600,&quot;asset_type&quot;:&quot;Work&quot;,&quot;button_location&quot;:&quot;profile&quot;}" href="https://www.academia.edu/attachments/44885809/download_file?st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&st=MTczMjQxNzA5MSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="24555600"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="24555600"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 24555600; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=24555600]").text(description); $(".js-view-count[data-work-id=24555600]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 24555600; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='24555600']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 24555600, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "362de751ca033778bcf9e2fa47f3ae69" } } $('.js-work-strip[data-work-id=24555600]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":24555600,"title":"Prenatal exposure to antibiotics, cesarean section and risk of childhood obesity","translated_title":"","metadata":{"abstract":"Background/Objectives:Cesarean section (CS) and antibiotic use during pregnancy may alter normal maternal-offspring microbiota exchange, thereby contributing to aberrant microbial colonization of the infant gut and increased susceptibility to obesity later in life. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="24555599"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/24555599/Prenatal_phthalate_and_early_childhood_bisphenol_A_exposures_increase_asthma_risk_in_inner_city_children"><img alt="Research paper thumbnail of Prenatal phthalate and early childhood bisphenol A exposures increase asthma risk in inner-city children" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/24555599/Prenatal_phthalate_and_early_childhood_bisphenol_A_exposures_increase_asthma_risk_in_inner_city_children">Prenatal phthalate and early childhood bisphenol A exposures increase asthma risk in inner-city children</a></div><div class="wp-workCard_item"><span>The Journal of allergy and clinical immunology</span><span>, 2014</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="24555599"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="24555599"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 24555599; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="24555598"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/24555598/Vinyl_flooring_in_the_home_is_associated_with_childrens_airborne_butylbenzyl_phthalate_and_urinary_metabolite_concentrations"><img alt="Research paper thumbnail of Vinyl flooring in the home is associated with children&#39;s airborne butylbenzyl phthalate and urinary metabolite concentrations" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/24555598/Vinyl_flooring_in_the_home_is_associated_with_childrens_airborne_butylbenzyl_phthalate_and_urinary_metabolite_concentrations">Vinyl flooring in the home is associated with children&#39;s airborne butylbenzyl phthalate and urinary metabolite concentrations</a></div><div class="wp-workCard_item"><span>Journal of exposure science &amp; environmental epidemiology</span><span>, Jan 18, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Prior studies have shown that vinyl flooring as well as the vinyl-softening plasticizers butylben...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Prior studies have shown that vinyl flooring as well as the vinyl-softening plasticizers butylbenzyl phthalate (BBzP) and di(2-ethylhexyl) phthalate (DEHP) are associated with asthma and airway inflammation. Although DEHP exposure is primarily dietary, whether home vinyl flooring contributes to indoor air and urinary metabolite concentrations for these two phthalates is unclear. Exposures to BBzP and DEHP were examined in a prospective birth cohort of New York City children (n=239) using: (i) visual observation of potential phthalate containing flooring, (ii) a 2-week home indoor air sample, and (iii) concurrent urinary metabolites in a subset (n=193). The category &amp;quot;vinyl or linoleum&amp;quot; flooring was observed in 135 (56%) of monitored rooms; these rooms had statistically significantly higher indoor air geometric mean concentrations of BBzP (23.9 ng/m(3)) than rooms with wood or carpet flooring (10.6 ng/m(3)). 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Children from homes with \u0026quot;vinyl or linoleum\u0026quot; flooring als...","publication_date":{"day":18,"month":1,"year":2015,"errors":{}},"publication_name":"Journal of exposure science \u0026 environmental epidemiology"},"translated_abstract":"Prior studies have shown that vinyl flooring as well as the vinyl-softening plasticizers butylbenzyl phthalate (BBzP) and di(2-ethylhexyl) phthalate (DEHP) are associated with asthma and airway inflammation. Although DEHP exposure is primarily dietary, whether home vinyl flooring contributes to indoor air and urinary metabolite concentrations for these two phthalates is unclear. Exposures to BBzP and DEHP were examined in a prospective birth cohort of New York City children (n=239) using: (i) visual observation of potential phthalate containing flooring, (ii) a 2-week home indoor air sample, and (iii) concurrent urinary metabolites in a subset (n=193). 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Exhaled No At Age 7-11 Years Is Elevated With Early Life But Not Recent Onset Of Allergic ...","internal_url":"https://www.academia.edu/24555596/Exhaled_No_At_Age_7_11_Years_Is_Elevated_With_Early_Life_But_Not_Recent_Onset_Of_Allergic_Sensitization","translated_internal_url":"","created_at":"2016-04-19T07:20:44.847-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":47333446,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":19203249,"work_id":24555596,"tagging_user_id":47333446,"tagged_user_id":null,"co_author_invite_id":128915,"email":"f***1@columbia.cdu","display_order":0,"name":"Frederica Perera","title":"Exhaled No At Age 7-11 Years Is Elevated With Early Life But Not Recent Onset Of Allergic Sensitization"}],"downloadable_attachments":[],"slug":"Exhaled_No_At_Age_7_11_Years_Is_Elevated_With_Early_Life_But_Not_Recent_Onset_Of_Allergic_Sensitization","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":47333446,"first_name":"Lori","middle_initials":"","last_name":"Hoepner","page_name":"LHoepner","domain_name":"independent","created_at":"2016-04-19T07:19:51.045-07:00","display_name":"Lori Hoepner","url":"https://independent.academia.edu/LHoepner"},"attachments":[],"research_interests":[{"id":151448,"name":"American","url":"https://www.academia.edu/Documents/in/American"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="14745252"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/14745252/Association_of_recent_exposure_to_ambient_metals_on_fractional_exhaled_nitric_oxide_in_9_11_year_old_inner_city_children"><img alt="Research paper thumbnail of Association of recent exposure to ambient metals on fractional exhaled nitric oxide in 9-11 year old inner-city children" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/14745252/Association_of_recent_exposure_to_ambient_metals_on_fractional_exhaled_nitric_oxide_in_9_11_year_old_inner_city_children">Association of recent exposure to ambient metals on fractional exhaled nitric oxide in 9-11 year old inner-city children</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://udesc.academia.edu/MariaRosa">Maria Rosa</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/LHoepner">Lori Hoepner</a></span></div><div class="wp-workCard_item"><span>Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society</span><span>, Jan 31, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Exposure to ambient metals in urban environments has been associated with wheeze, and emergency r...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Exposure to ambient metals in urban environments has been associated with wheeze, and emergency room visits and hospitalizations due to respiratory illness. However, the effect of ambient metals exposure on airway inflammation, and how these associations may be modified by seroatopy, has not been determined. Fractional exhaled nitric oxide (FENO) is a reliable proxy marker of airway inflammation. We hypothesized that recent ambient concentrations of Ni, V, Zn and Fe would be associated differentially with proximal and distal fractions of exhaled NO, and that these associations would be modified by seroatopy. As part of the Columbia Center for Children&amp;#39;s Environmental Health (CCCEH) birth cohort study, 9-11 year old children (n=192) were evaluated. Ambient measures of Ni, V, Zn and Fe were obtained from a local central monitoring site and averaged over 9 days based on three 24h measures every third day. 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However, the effect of ambient metals exposure on airway inflammation, and how these associations may be modified by seroatopy, has not been determined. Fractional exhaled nitric oxide (FENO) is a reliable proxy marker of airway inflammation. We hypothesized that recent ambient concentrations of Ni, V, Zn and Fe would be associated differentially with proximal and distal fractions of exhaled NO, and that these associations would be modified by seroatopy. As part of the Columbia Center for Children\u0026#39;s Environmental Health (CCCEH) birth cohort study, 9-11 year old children (n=192) were evaluated. Ambient measures of Ni, V, Zn and Fe were obtained from a local central monitoring site and averaged over 9 days based on three 24h measures every third day. 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As part of the Columbia Center for Children\u0026#39;s Environmental Health (CCCEH) birth cohort study, 9-11 year old children (n=192) were evaluated. Ambient measures of Ni, V, Zn and Fe were obtained from a local central monitoring site and averaged over 9 days based on three 24h measures every third day. 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Exposure","url":"https://www.academia.edu/Documents/in/Environmental_Exposure"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="24555595"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/24555595/Asthma_in_Inner_City_Children_at_5_11_Years_of_Age_and_Prenatal_Exposure_to_Phthalates_The_Columbia_Center_for_Children_s_Environmental_Health_Cohort"><img alt="Research paper thumbnail of Asthma in Inner-City Children at 5-11 Years of Age and Prenatal Exposure to Phthalates: The Columbia Center for Children’s Environmental Health Cohort" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/24555595/Asthma_in_Inner_City_Children_at_5_11_Years_of_Age_and_Prenatal_Exposure_to_Phthalates_The_Columbia_Center_for_Children_s_Environmental_Health_Cohort">Asthma in Inner-City Children at 5-11 Years of Age and Prenatal Exposure to Phthalates: The Columbia Center for Children’s Environmental Health Cohort</a></div><div class="wp-workCard_item"><span>Environmental Health Perspectives</span><span>, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Studies suggest that phthalate exposures may adversely affect child respiratory health. We evalua...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Studies suggest that phthalate exposures may adversely affect child respiratory health. We evaluated associations between asthma diagnosed in children between 5 and 11 years of age and prenatal exposures to butylbenzyl phthalate (BBzP), di-n-butyl phthalate (DnBP), di(2-ethylhexyl) phthalate (DEHP), and diethyl phthalate (DEP). Phthalate metabolites were measured in spot urine collected from 300 pregnant inner-city women. Children were examined by an allergist or pulmonologist based on the first parental report of wheeze, other respiratory symptoms, and/or use of asthma rescue/controller medication in the preceding 12 months on repeat follow-up questionnaires. Standardized diagnostic criteria were used to classify these children as either having or not having current asthma at the time of the physician examination. Children without any report of wheeze or the other asthma-like symptoms were classified as nonasthmatics at the time of the last negative questionnaire. Modified Poisson regression analyses were used to estimate relative risks (RR) controlling for specific gravity and potential confounders. Of 300 children, 154 (51%) were examined by a physician because of reports of wheeze, other asthma-like symptoms, and/or medication use; 94 were diagnosed with current asthma and 60 without current asthma. The remaining 146 children were classified as nonasthmatic. Compared with levels in nonasthmatics, prenatal metabolites of BBzP and DnBP were associated with a history of asthma-like symptoms (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05) and with the diagnosis of current asthma: RR = 1.17 (95% CI: 1.01, 1.35) and RR = 1.25 (95% CI: 1.04, 1.51) per natural log-unit increase, respectively. Risk of current asthma was &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt; 70% higher among children with maternal prenatal BBzP and DnBP metabolite concentrations in the third versus the first tertile. Prenatal exposure to BBzP and DnBP may increase the risk of asthma among inner-city children. However, because this is the first such finding, results require replication.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="24555595"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="24555595"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 24555595; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=24555595]").text(description); $(".js-view-count[data-work-id=24555595]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 24555595; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='24555595']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 24555595, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=24555595]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":24555595,"title":"Asthma in Inner-City Children at 5-11 Years of Age and Prenatal Exposure to Phthalates: The Columbia Center for Children’s Environmental Health Cohort","translated_title":"","metadata":{"abstract":"Studies suggest that phthalate exposures may adversely affect child respiratory health. We evaluated associations between asthma diagnosed in children between 5 and 11 years of age and prenatal exposures to butylbenzyl phthalate (BBzP), di-n-butyl phthalate (DnBP), di(2-ethylhexyl) phthalate (DEHP), and diethyl phthalate (DEP). Phthalate metabolites were measured in spot urine collected from 300 pregnant inner-city women. Children were examined by an allergist or pulmonologist based on the first parental report of wheeze, other respiratory symptoms, and/or use of asthma rescue/controller medication in the preceding 12 months on repeat follow-up questionnaires. Standardized diagnostic criteria were used to classify these children as either having or not having current asthma at the time of the physician examination. Children without any report of wheeze or the other asthma-like symptoms were classified as nonasthmatics at the time of the last negative questionnaire. Modified Poisson regression analyses were used to estimate relative risks (RR) controlling for specific gravity and potential confounders. Of 300 children, 154 (51%) were examined by a physician because of reports of wheeze, other asthma-like symptoms, and/or medication use; 94 were diagnosed with current asthma and 60 without current asthma. The remaining 146 children were classified as nonasthmatic. Compared with levels in nonasthmatics, prenatal metabolites of BBzP and DnBP were associated with a history of asthma-like symptoms (p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05) and with the diagnosis of current asthma: RR = 1.17 (95% CI: 1.01, 1.35) and RR = 1.25 (95% CI: 1.04, 1.51) per natural log-unit increase, respectively. Risk of current asthma was \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt; 70% higher among children with maternal prenatal BBzP and DnBP metabolite concentrations in the third versus the first tertile. Prenatal exposure to BBzP and DnBP may increase the risk of asthma among inner-city children. However, because this is the first such finding, results require replication.","publication_date":{"day":null,"month":null,"year":2014,"errors":{}},"publication_name":"Environmental Health Perspectives"},"translated_abstract":"Studies suggest that phthalate exposures may adversely affect child respiratory health. We evaluated associations between asthma diagnosed in children between 5 and 11 years of age and prenatal exposures to butylbenzyl phthalate (BBzP), di-n-butyl phthalate (DnBP), di(2-ethylhexyl) phthalate (DEHP), and diethyl phthalate (DEP). Phthalate metabolites were measured in spot urine collected from 300 pregnant inner-city women. Children were examined by an allergist or pulmonologist based on the first parental report of wheeze, other respiratory symptoms, and/or use of asthma rescue/controller medication in the preceding 12 months on repeat follow-up questionnaires. Standardized diagnostic criteria were used to classify these children as either having or not having current asthma at the time of the physician examination. Children without any report of wheeze or the other asthma-like symptoms were classified as nonasthmatics at the time of the last negative questionnaire. Modified Poisson regression analyses were used to estimate relative risks (RR) controlling for specific gravity and potential confounders. Of 300 children, 154 (51%) were examined by a physician because of reports of wheeze, other asthma-like symptoms, and/or medication use; 94 were diagnosed with current asthma and 60 without current asthma. The remaining 146 children were classified as nonasthmatic. Compared with levels in nonasthmatics, prenatal metabolites of BBzP and DnBP were associated with a history of asthma-like symptoms (p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05) and with the diagnosis of current asthma: RR = 1.17 (95% CI: 1.01, 1.35) and RR = 1.25 (95% CI: 1.04, 1.51) per natural log-unit increase, respectively. Risk of current asthma was \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt; 70% higher among children with maternal prenatal BBzP and DnBP metabolite concentrations in the third versus the first tertile. Prenatal exposure to BBzP and DnBP may increase the risk of asthma among inner-city children. However, because this is the first such finding, results require replication.","internal_url":"https://www.academia.edu/24555595/Asthma_in_Inner_City_Children_at_5_11_Years_of_Age_and_Prenatal_Exposure_to_Phthalates_The_Columbia_Center_for_Children_s_Environmental_Health_Cohort","translated_internal_url":"","created_at":"2016-04-19T07:20:44.376-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":47333446,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":19203242,"work_id":24555595,"tagging_user_id":47333446,"tagged_user_id":null,"co_author_invite_id":128915,"email":"f***1@columbia.cdu","display_order":0,"name":"Frederica Perera","title":"Asthma in Inner-City Children at 5-11 Years of Age and Prenatal Exposure to Phthalates: The Columbia Center for Children’s Environmental Health Cohort"},{"id":19203283,"work_id":24555595,"tagging_user_id":47333446,"tagged_user_id":null,"co_author_invite_id":424338,"email":"r***5@columbia.edu","display_order":4194304,"name":"Robin Whyatt","title":"Asthma in Inner-City Children at 5-11 Years of Age and Prenatal Exposure to Phthalates: The Columbia Center for Children’s Environmental Health Cohort"},{"id":19203311,"work_id":24555595,"tagging_user_id":47333446,"tagged_user_id":289615080,"co_author_invite_id":150409,"email":"m***7@columbia.edu","display_order":6291456,"name":"Matthew Perzanowski","title":"Asthma in Inner-City Children at 5-11 Years of Age and Prenatal Exposure to Phthalates: The Columbia Center for Children’s Environmental Health Cohort"},{"id":19203339,"work_id":24555595,"tagging_user_id":47333446,"tagged_user_id":null,"co_author_invite_id":424349,"email":"k***8@columbia.edu","display_order":7340032,"name":"Kathleen Donohue","title":"Asthma in Inner-City Children at 5-11 Years of Age and Prenatal Exposure to Phthalates: The Columbia Center for Children’s Environmental Health Cohort"},{"id":19203378,"work_id":24555595,"tagging_user_id":47333446,"tagged_user_id":null,"co_author_invite_id":391570,"email":"a***t@hsph.harvard.edu","display_order":7864320,"name":"Allan Just","title":"Asthma in Inner-City Children at 5-11 Years of Age and Prenatal Exposure to Phthalates: The Columbia Center for Children’s Environmental Health Cohort"}],"downloadable_attachments":[],"slug":"Asthma_in_Inner_City_Children_at_5_11_Years_of_Age_and_Prenatal_Exposure_to_Phthalates_The_Columbia_Center_for_Children_s_Environmental_Health_Cohort","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":47333446,"first_name":"Lori","middle_initials":"","last_name":"Hoepner","page_name":"LHoepner","domain_name":"independent","created_at":"2016-04-19T07:19:51.045-07:00","display_name":"Lori Hoepner","url":"https://independent.academia.edu/LHoepner"},"attachments":[],"research_interests":[{"id":9968,"name":"Asthma","url":"https://www.academia.edu/Documents/in/Asthma"},{"id":22772,"name":"Urban Health","url":"https://www.academia.edu/Documents/in/Urban_Health"},{"id":58054,"name":"Environmental Sciences","url":"https://www.academia.edu/Documents/in/Environmental_Sciences"},{"id":62550,"name":"Pregnancy","url":"https://www.academia.edu/Documents/in/Pregnancy"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":248366,"name":"New York","url":"https://www.academia.edu/Documents/in/New_York"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":736321,"name":"Environmental Pollutants","url":"https://www.academia.edu/Documents/in/Environmental_Pollutants"},{"id":1312021,"name":"Environmental Exposure","url":"https://www.academia.edu/Documents/in/Environmental_Exposure"},{"id":1330083,"name":"Respiratory Sounds","url":"https://www.academia.edu/Documents/in/Respiratory_Sounds"}],"urls":[]}, dispatcherData: dispatcherData }); 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