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<!DOCTYPE html> <html lang="en"> <head> <meta charset="utf-8"> <meta name="viewport" content="width=device-width, initial-scale=1"> <title>KEGG NETWORK Database</title> <link rel="stylesheet" href="/css/kegg25.css"> <style> #dbnav ul li { padding: 6px 0 6px 18px; } p { margin: 4px 0 0 10px; } div.list li { margin-left: 0; } </style> </head> <body> <div id="topnav" ontouchstart=""> <div class="navlist"> <a href="/kegg/">KEGG</a> </div> <div class="dropdown"> Databases <div class="dropdown-content"> <ul> <li><a href="/kegg/pathway.html">Pathway</a></li> <li><a href="/kegg/brite.html">Brite</a></li> <li><a href="/kegg/ko.html">KO</a></li> <li><a href="/kegg/genes.html">Genes</a></li> <li><a href="/kegg/compound/">Chemical</a></li> <li><a href="/kegg/disease/">Disease</a></li> <li><a href="/kegg/drug/">Drug</a></li> <li><a href="/kegg/medicus.html">Medicus</a></li> </ul> </div> </div> <div class="dropdown"> Tools <div class="dropdown-content"> <ul> <li><a href="/kegg/mapper/">Mapper</a></li> <li><a href="/kegg/webapp/">Web Apps</a></li> <li><a href="/kegg/syntax/">Syntax</a></li> <li><a href="/kegg/annotation/">Annotation</a></li> </ul> </div> </div> <div class="dropdown"> Auto annotation <div class="dropdown-content"> <ul> <li><a href="https://www.kegg.jp/blastkoala/">BlastKOALA</a></li> <li><a href="https://www.kegg.jp/ghostkoala/">GhostKOALA</a></li> </ul> </div> </div> <div class="navlist"> <a href="https://www.kanehisa.jp/">Kanehisa Lab</a> </div> </div> <div id="header"> <div class="logo"> <a href="/kegg/"><img src="/Fig/kegg128.gif" alt="KEGG icon"></a> </div> <div class="title"> <h2 class="txt5">KEGG NETWORK Database</h2> <h5>From gene variation to network variation</h5> </div> </div> <div id="dbnav" class="bar5"> <ul> <li><a href="/kegg/kegg2.html">KEGG2</a></li> <li><a href="/kegg/pathway.html">PATHWAY</a></li> <li><a href="/kegg/brite.html">BRITE</a></li> <li><a href="/kegg/module.html">MODULE</a></li> <li><a href="/kegg/ko.html">KO</a></li> <li><span class="current">NETWORK</span></li> <li><a href="/kegg/disease/">DISEASE</a></li> <li><a href="/kegg/drug/">DRUG</a></li> <li><a href="/kegg/medicus.html">MEDICUS</a></li> </ul> </div> <div id="content">  <div class="searchbox"> <form action="https://www.kegg.jp/medicus-bin/search_medicus"> <span class="small">Search NETWORK in KEGG MEDICUS</span> <br> <input type="search" name="q" size="40"> <input type="hidden" name="display" value="network"> <input type="hidden" name="from" value="network"> <input type="submit" value="Go"> </form> </div> <div class="searchbox"> <form action="https://www.kegg.jp/medicus-bin/search_medicus"> <span class="small">Search human gene VARIANT in KEGG MEDICUS</span> <br> <input type="search" name="q" size="40"> <input type="hidden" name="display" value="variant"> <input type="hidden" name="from" value="variant"> <input type="submit" value="Go"> </form> </div> <div class="main"> <hr class="frame5"> <h4 class="txt5">Network Variation Maps</h4> <div class="indent"> <b>KEGG NETWORK</b> represents a renewed attempt by KEGG to capture knowledge of diseases and drugs in terms of perturbed molecular networks (see Background of <a href="/kegg/disease/">KEGG DISEASE</a>). It accumulates variations of molecular interaction/reaction networks in terms of network variation maps (such as <a href="/network/nt06210" target="_blank">nt06210</a>) consisting of network elements (such as <a href="/entry/N00014" target="_blank">N00014</a>). The notation of network variation maps is as follows. </div> <div class="indent2"> <div style="float:left;"> <div class="frame5"> <table> <tr> <td class="center">Network element</td> <td class="center">Coloring</td> </tr> <tr> <td>Reference network</td> <td><span style="color:green">Green</span></td> </tr> <tr> <td>Variant network containing<br>    Human gene variant<br>    Pathogen gene/protein<br>    Environmental factor</td> <td><br> <span style="color:red">Red</span><br> <span style="color:purple">Purple</span><br> <span style="color:blue">Blue</span></td> </tr> <tr> <td>Drug-target relation</td> <td><span style="color:navy">Navy</span></td> </tr> </table> </div> <br> Gain-of-function variant indicated by <span style="line-height:14px;font-size:16px;">&nearr;</span> </div> <div style="float:left; margin-left:40px;"> <table class="frame5"> <tr> <td>Edge  </td> <td>Interaction/reaction</td> <tr> <td><span style="line-height:14px;font-size:16px;">→  </span></td> <td>Activation</td> </tr> <tr> <td><span style="line-height:14px;font-size:16px;">&dashv;</span></td> <td>Inhibition</td> </tr> <tr> <td><span style="line-height:14px;font-size:16px;">＝</span></td> <td>Complex formation</td> </tr> <tr> <td><span style="line-height:14px;font-size:16px;">&solbar;</span></td> <td>Missing interaction or reaction</td> </tr> <tr> <td><span style="line-height:14px;font-size:16px;">⇒</span></td> <td>Expression</td> </tr> <tr> <td><span style="line-height:14px;font-size:16px;">&Dashv;</span></td> <td>Repression</td> </tr> <tr> <td><span style="line-height:14px;font-size:16px;">—</span></td> <td>Substrate binding to enzyme or transporter</td> </tr> <tr> <td><span style="line-height:14px;font-size:16px;">→</span></td> <td>Enzymatic reaction or transport process</td> </tr> <tr class="top"> <td><span style="line-height:14px;font-size:16px;">&rrarr;</span></td> <td>Enzyme-enzyme relation of successive reactions</td> </tr> </table> </div> <div style="clear:both;"></div> </div> <hr class="frame5"> <br> <table style="border:0; border-collapse:collapse; width:780px;"> <tr class="top"><td style="width:50%;"> <b id="metab">Pathway view</b> <p>Carbohydrate metabolism</p> <div class="list"> <dl> <dt>06031</dt><dd><a href="/network/nt06031">Citrate cycle and pyruvate metabolism</a></dd> <dt>06017</dt><dd><a href="/network/nt06017&target=1">Glycogen metabolism</a></dd> <dt>06023</dt><dd><a href="/network/nt06023">Galactose degradation</a></dd> </dl> </div> <div class="clear"></div> <p>Lipid/glycolipid metabolism</p> <div class="list"> <dl> <dt>06020</dt><dd><a href="/network/nt06020">beta-Oxidation in mitochondria</a></dd> <dt>06021</dt><dd><a href="/network/nt06021">beta-Oxidation in peroxisome</a></dd> <dt>06034</dt><dd><a href="/network/nt06034">Cholesterol biosynthesis</a></dd> <dt>06019</dt><dd><a href="/network/nt06019">Steroid hormone biosynthesis</a></dd> <dt>06022</dt><dd><a href="/network/nt06022">Bile acid biosynthesis</a></dd> <dt>06014</dt><dd><a href="/network/nt06014&target=1">Sphingolipid degradation</a></dd> </dl> </div> <div class="clear"></div> <p>Nucleotide metabolism</p> <div class="list"> <dl> <dt>06027</dt><dd><a href="/network/nt06027">Purine salvage pathway</a></dd> </dl> </div> <div class="clear"></div> <p>Amino acid metabolism</p> <div class="list"> <dl> <dt>06033</dt><dd><a href="/network/nt06033">Glycine, serine and arginine metabolism</a></dd> <dt>06030</dt><dd><a href="/network/nt06030">Methionine metabolism</a></dd> <dt>06024</dt><dd><a href="/network/nt06024">Valine, leucine and isoleucine degradation</a></dd> <dt>06036</dt><dd><a href="/network/nt06036">Lysine degradation</a></dd> <dt>06010</dt><dd><a href="/network/nt06010&target=1">Urea cycle</a></dd> <dt>06037</dt><dd><a href="/network/nt06037">Histidine metabolism</a></dd> <dt>06016</dt><dd><a href="/network/nt06016">Phenylalanine and tyrosine metabolism</a></dd> <dt>06028</dt><dd><a href="/network/nt06028&target=1">Dopamine and serotonin metabolism</a></dd> <dt>06026</dt><dd><a href="/network/nt06026">Glutathione biosynthesis</a></dd> </dl> </div> <div class="clear"></div> <p>Glycan/glycoprotein metabolism</p> <div class="list"> <dl> <dt>06015</dt><dd><a href="/network/nt06015">N-Glycan biosynthesis</a></dd> <dt>06013</dt><dd><a href="/network/nt06013">O-Glycan biosynthesis</a></dd> <dt>06029</dt><dd><a href="/network/nt06029">Glycosaminoglycan biosynthesis</a></dd> <dt>06012</dt><dd><a href="/network/nt06012&target=1">Glycosaminoglycan degradation</a></dd> <dt>06018</dt><dd><a href="/network/nt06018">GPI-anchor biosynthesis</a></dd> <dt>06035</dt><dd><a href="/network/nt06035">Blood group carbohydrate antigen biosynthesis</a></dd> </dl> </div> <div class="clear"></div> <p>Cofactor/vitamin metabolism</p> <div class="list"> <dl> <dt>06032</dt><dd><a href="/network/nt06032">Lipoic acid metabolism</a></dd> <dt>06038</dt><dd><a href="/network/nt06038">Folate metabolism</a></dd> <dt>06025</dt><dd><a href="/network/nt06025">Molybdenum cofactor biosynthesis</a></dd> <dt>06011</dt><dd><a href="/network/nt06011">Heme biosynthesis</a></dd> <dt>06538</dt><dd><a href="/network/nt06538">Cobalamin transport and metabolism</a></dd> </dl> </div> <div class="clear"></div> <p>Replication and repair</p> <div class="list"> <dl> <dt>06509</dt><dd><a href="/network/nt06509">DNA replication</a></dd> <dt>06510</dt><dd><a href="/network/nt06510">Telomere length regulation</a></dd> <dt>06504</dt><dd><a href="/network/nt06504">Base excision repair</a></dd> <dt>06502</dt><dd><a href="/network/nt06502">Nucleotide excision repair</a></dd> <dt>06503</dt><dd><a href="/network/nt06503">Mismatch repair</a></dd> <dt>06506</dt><dd><a href="/network/nt06506">Double-strand break repair</a></dd> <dt>06508</dt><dd><a href="/network/nt06508">Interstrand crosslink repair</a></dd> </dl> </div> <div class="clear"></div> <p>Signal transduction</p> <div class="list"> <dl> <dt>06526</dt><dd><a href="/network/nt06526">MAPK signaling</a></dd> <dt>06530</dt><dd><a href="/network/nt06530">PI3K signaling</a></dd> <dt>06505</dt><dd><a href="/network/nt06505">WNT signaling</a></dd> <dt>06511</dt><dd><a href="/network/nt06511">NOTCH signaling</a></dd> <dt>06501</dt><dd><a href="/network/nt06501">HH signaling</a></dd> <dt>06507</dt><dd><a href="/network/nt06507">TGFB signaling</a></dd> <dt>06518</dt><dd><a href="/network/nt06518">JAK-STAT signaling</a></dd> <dt>06516</dt><dd><a href="/network/nt06516">TNF signaling</a></dd> <dt>06528</dt><dd><a href="/network/nt06528">Calcium signaling</a></dd> <dt>06522</dt><dd><a href="/network/nt06522">mTOR signaling</a></dd> <dt>06542</dt><dd><a href="/network/nt06542">HIF signaling</a> <span class="new">New!</span></dd> <dt>06543</dt><dd><a href="/network/nt06543">NRG-ERBB signaling</a> <span class="new">New!</span></dd> </dl> </div> <div class="clear"></div> <p>Cellular process</p> <div class="list"> <dl> <dt>06523</dt><dd><a href="/network/nt06523">Epigenetic regulation by Polycomb complexes</a></dd> <dt>06512</dt><dd><a href="/network/nt06512">Chromosome cohesion and segregation</a></dd> <dt>06515</dt><dd><a href="/network/nt06515">Regulation of kinetochore-microtubule interactions</a></dd> <dt>06534</dt><dd><a href="/network/nt06534">Unfolded protein response</a></dd> <dt>06532</dt><dd><a href="/network/nt06532">Autophagy</a></dd> <dt>06536</dt><dd><a href="/network/nt06536">Mitophagy</a></dd> <dt>06535</dt><dd><a href="/network/nt06535">Efferocytosis</a></dd> <dt>06524</dt><dd><a href="/network/nt06524">Apoptosis</a></dd> <dt>06525</dt><dd><a href="/network/nt06525">Ferroptosis</a></dd> <dt>06527</dt><dd><a href="/network/nt06527">Necroptosis</a></dd> <dt>06529</dt><dd><a href="/network/nt06529">Thermogenesis</a></dd> <dt>06539</dt><dd><a href="/network/nt06539">Cytoskeleton in muscle cells</a></dd> <dt>06541</dt><dd><a href="/network/nt06541">Cytoskeleton in neurons</a></dd> <dt>06544</dt><dd><a href="/network/nt06544">Neuroactive ligand signaling</a> <span class="new">New!</span></dd> </dl> </div> <div class="clear"></div> <p>Immune system</p> <div class="list"> <dl> <dt>06513</dt><dd><a href="/network/nt06513">Complement cascade</a></dd> <dt>06514</dt><dd><a href="/network/nt06514">Coagulation cascade</a></dd> <dt>06517</dt><dd><a href="/network/nt06517">TLR signaling</a></dd> <dt>06521</dt><dd><a href="/network/nt06521">NLR signaling</a></dd> <dt>06519</dt><dd><a href="/network/nt06519">RLR signaling</a></dd> <dt>06520</dt><dd><a href="/network/nt06520">CGAS-STING signaling</a></dd> <dt>06537</dt><dd><a href="/network/nt06537">TCR/BCR signaling</a></dd> <dt>06533</dt><dd><a href="/network/nt06533">Chemokine signaling</a></dd> </dl> </div> <div class="clear"></div> <p>Endocrine system</p> <div class="list"> <dl> <dt>06310</dt><dd><a href="/network/nt06310">CRH-ACTH-cortisol signaling</a></dd> <dt>06322</dt><dd><a href="/network/nt06322">TRH-TSH-TH signaling</a></dd> <dt>06323</dt><dd><a href="/network/nt06323">KISS1-GnRH-LH/FSH-E2 signaling</a></dd> <dt>06324</dt><dd><a href="/network/nt06324">GHRH-GH-IGF signaling</a></dd> <dt>06318</dt><dd><a href="/network/nt06318">CaSR-PTH signaling</a></dd> <dt>06316</dt><dd><a href="/network/nt06316">Renin-angiotensin-aldosterone signaling</a></dd> <dt>06325</dt><dd><a href="/network/nt06325">Hormone/cytokine signaling</a></dd> <dt>06320</dt><dd><a href="/network/nt06320">APOB-LDLR signaling</a></dd> </dl> </div> <div class="clear"></div> </td><td> <b id="cancer">Disease view</b> <p>Cancer (See <a href="/kegg/kegg1c.html#cancer">Color codes</a> of cancer types)</p> <div class="list" style="float:left; width:230px;"> <dl> <dt>06260</dt><dd><a href="/network/nt06260">Colorectal cancer</a></dd> <dt>06261</dt><dd><a href="/network/nt06261">Gastric cancer</a></dd> <dt>06262</dt><dd><a href="/network/nt06262">Pancreatic cancer</a></dd> <dt>06263</dt><dd><a href="/network/nt06263">Hepatocellular carcinoma</a></dd> <dt>06264</dt><dd><a href="/network/nt06264">Renal cell carcinoma</a></dd> <dt>06265</dt><dd><a href="/network/nt06265">Bladder cancer</a></dd> <dt>06266</dt><dd><a href="/network/nt06266">Non-small cell lung cancer</a></dd> <dt>06267</dt><dd><a href="/network/nt06267">Small cell lung cancer</a></dd> <dt>06268</dt><dd><a href="/network/nt06268">Melanoma</a></dd> <dt>06269</dt><dd><a href="/network/nt06269">Basal cell carcinoma</a></dd> <dt>06270</dt><dd><a href="/network/nt06270">Breast cancer</a></dd> <dt>06271</dt><dd><a href="/network/nt06271">Endometrial cancer</a></dd> <dt>06272</dt><dd><a href="/network/nt06272">Prostate cancer</a></dd> <dt>06273</dt><dd><a href="/network/nt06273">Glioma</a></dd> <dt>06274</dt><dd><a href="/network/nt06274">Thyroid cancer</a></dd> <dt>06275</dt><dd><a href="/network/nt06275">Acute myeloid leukemia</a></dd> <dt>06276</dt><dd><a href="/network/nt06276">Chronic myeloid leukemia</a></dd> </dl> </div> <div class="list" style="margin-left:0; float:left;"> <ul> <li>[<a href="/pathway/hsa05210">hsa05210</a>]</li> <li>[<a href="/pathway/hsa05226">hsa05226</a>]</li> <li>[<a href="/pathway/hsa05212">hsa05212</a>]</li> <li>[<a href="/pathway/hsa05225">hsa05225</a>]</li> <li>[<a href="/pathway/hsa05211">hsa05211</a>]</li> <li>[<a href="/pathway/hsa05219">hsa05219</a>]</li> <li>[<a href="/pathway/hsa05223">hsa05223</a>]</li> <li>[<a href="/pathway/hsa05222">hsa05222</a>]</li> <li>[<a href="/pathway/hsa05218">hsa05218</a>]</li> <li>[<a href="/pathway/hsa05217">hsa05217</a>]</li> <li>[<a href="/pathway/hsa05224">hsa05224</a>]</li> <li>[<a href="/pathway/hsa05213">hsa05213</a>]</li> <li>[<a href="/pathway/hsa05215">hsa05215</a>]</li> <li>[<a href="/pathway/hsa05214">hsa05214</a>]</li> <li>[<a href="/pathway/hsa05216">hsa05216</a>]</li> <li>[<a href="/pathway/hsa05221">hsa05221</a>]</li> <li>[<a href="/pathway/hsa05220">hsa05220</a>]</li> </ul> </div> <div class="clear"></div> <p>Cancer signaling</p> <div class="list"> <dl> <dt>06210</dt><dd><a href="/network/nt06210">ERK signaling</a></dd> <dt>06214</dt><dd><a href="/network/nt06214">PI3K signaling</a></dd> <dt>06213</dt><dd><a href="/network/nt06213">Other RAS signaling</a></dd> <dt>06211</dt><dd><a href="/network/nt06211">Other MAPK signaling</a></dd> <dt>06215</dt><dd><a href="/network/nt06215">WNT signaling</a></dd> <dt>06216</dt><dd><a href="/network/nt06216">NOTCH signaling</a></dd> <dt>06217</dt><dd><a href="/network/nt06217">HH signaling</a></dd> <dt>06218</dt><dd><a href="/network/nt06218">TGFB signaling</a></dd> <dt>06219</dt><dd><a href="/network/nt06219">JAK-STAT signaling</a></dd> <dt>06220</dt><dd><a href="/network/nt06220">Calcium signaling</a></dd> <dt>06234</dt><dd><a href="/network/nt06234">cAMP signaling</a></dd> <dt>06222</dt><dd><a href="/network/nt06222">IFN signaling</a></dd> <dt>06223</dt><dd><a href="/network/nt06223">TNF signaling</a></dd> <dt>06224</dt><dd><a href="/network/nt06224">CXCR signaling</a></dd> <dt>06225</dt><dd><a href="/network/nt06225">HIF-1 signaling</a></dd> <dt>06226</dt><dd><a href="/network/nt06226">KEAP1-NRF2 signaling</a></dd> <dt>06227</dt><dd><a href="/network/nt06227">Nuclear receptor signaling</a></dd> <dt>06229</dt><dd><a href="/network/nt06229">MHC presentation</a></dd> <dt>06230</dt><dd><a href="/network/nt06230">Cell cycle</a></dd> <dt>06231</dt><dd><a href="/network/nt06231">Apoptosis</a></dd> <dt>06232</dt><dd><a href="/network/nt06232">Telomerase activity</a></dd> <dt>06240</dt><dd><a href="/network/nt06240">Transcription</a></dd> <dt>06250</dt><dd><a href="/network/nt06250">DNA adduct formation</a></dd> <dt>06251</dt><dd><a href="/network/nt06251">CYP-mediated ROS formation</a></dd> <dt>06252</dt><dd><a href="/network/nt06252">Mitochondrial ROS formation</a></dd> <dt>06253</dt><dd><a href="/network/nt06253">Antioxidant system</a></dd> </dl> </div> <div class="clear"></div> <p>Neurodegenerative disease</p> <div class="list" style="float:left; width:260px;"> <dl> <dt>06460</dt><dd><a href="/network/nt06460">Alzheimer disease</a></dd> <dt>06463</dt><dd><a href="/network/nt06463">Parkinson disease</a></dd> <dt>06464</dt><dd><a href="/network/nt06464">Amyotrophic lateral sclerosis</a></dd> <dt>06461</dt><dd><a href="/network/nt06461">Huntington disease</a></dd> <dt>06462</dt><dd><a href="/network/nt06462">Spinocerebellar ataxia</a></dd> <dt>06465</dt><dd><a href="/network/nt06465">Prion disease</a></dd> <dt>06466</dt><dd><a href="/network/nt06466">Pathways of neurodegeneration</a></dd> </dl> </div> <div class="list" style="margin-left:0; float:left;"> <ul> <li>[<a href="/pathway/hsa05010">hsa05010</a>]</li> <li>[<a href="/pathway/hsa05012">hsa05012</a>]</li> <li>[<a href="/pathway/hsa05014">hsa05014</a>]</li> <li>[<a href="/pathway/hsa05016">hsa05016</a>]</li> <li>[<a href="/pathway/hsa05017">hsa05017</a>]</li> <li>[<a href="/pathway/hsa05020">hsa05020</a>]</li> <li>[<a href="/pathway/hsa05022">hsa05022</a>]</li> </ul> </div> <div class="clear"></div> <p>Endocrine and metabolic disease</p> <div class="list" style="float:left; width:260px;"> <dl> <dt>06360</dt><dd><a href="/network/nt06360">Cushing syndrome</a></dd> </dl> </div> <div class="list" style="margin-left:0; float:left;"> <ul style="margin-bottom:0;"> <li>[<a href="/pathway/hsa04934">hsa04934</a>]</li> </ul> </div> <div class="clear"></div> <p>Viral infection (*oncovirus)</p> <div class="list" style="float:left; width:260px;"> <dl> <dt>06160*</dt><dd><a href="/network/nt06160">Human T-cell leukemia virus 1</a></dd> <dt>06161</dt><dd><a href="/network/nt06161">Human immunodeficiency virus 1</a></dd> <dt>06162*</dt><dd><a href="/network/nt06162">Hepatitis B virus</a></dd> <dt>06163*</dt><dd><a href="/network/nt06163">Hepatitis C virus</a></dd> <dt>06171</dt><dd><a href="/network/nt06171">SARS coronavirus 2</a></dd> <dt>06170</dt><dd><a href="/network/nt06170">Influenza A virus</a></dd> <dt>06169</dt><dd><a href="/network/nt06169">Measles virus</a></dd> <dt>06168</dt><dd><a href="/network/nt06168">Herpes simplex virus 1</a></dd> <dt>06167</dt><dd><a href="/network/nt06167">Human cytomegalovirus</a></dd> <dt>06164*</dt><dd><a href="/network/nt06164">Kaposi sarcoma herpesvirus</a></dd> <dt>06165*</dt><dd><a href="/network/nt06165">Epstein-Barr virus</a></dd> <dt>06166*</dt><dd><a href="/network/nt06166">Human papillomavirus</a></dd> </dl> </div> <div class="list" style="margin-left:0; float:left;"> <ul> <li>[<a href="/pathway/hsa05166">hsa05166</a>]</li> <li>[<a href="/pathway/hsa05170">hsa05170</a>]</li> <li>[<a href="/pathway/hsa05161">hsa05161</a>]</li> <li>[<a href="/pathway/hsa05160">hsa05160</a>]</li> <li>[<a href="/pathway/hsa05171">hsa05171</a>]</li> <li>[<a href="/pathway/hsa05164">hsa05164</a>]</li> <li>[<a href="/pathway/hsa05162">hsa05162</a>]</li> <li>[<a href="/pathway/hsa05168">hsa05168</a>]</li> <li>[<a href="/pathway/hsa05163">hsa05163</a>]</li> <li>[<a href="/pathway/hsa05167">hsa05167</a>]</li> <li>[<a href="/pathway/hsa05169">hsa05169</a>]</li> <li>[<a href="/pathway/hsa05165">hsa05165</a>]</li> </ul> </div> <div class="clear"></div> <p>Bacterial infection</p> <div class="list" style="float:left; width:260px;"> <dl> <dt>06180</dt><dd><a href="/network/nt06180">Pathogenic Escherichia coli</a></dd> <dt>06181</dt><dd><a href="/network/nt06181">Salmonella</a></dd> <dt>06182</dt><dd><a href="/network/nt06182">Shigella</a></dd> <dt>06183</dt><dd><a href="/network/nt06183">Yersinia</a></dd> </dl> </div> <div class="list" style="margin-left:0; float:left;"> <ul> <li>[<a href="/pathway/hsa05130">hsa05130</a>]</li> <li>[<a href="/pathway/hsa05132">hsa05132</a>]</li> <li>[<a href="/pathway/hsa05131">hsa05131</a>]</li> <li>[<a href="/pathway/hsa05135">hsa05135</a>]</li> </ul> </div> <div class="clear"></div> <div class="clear"></div> </td></tr> </table> <hr class="frame5"> <i>Last updated: April 10, 2025</i> </div>  </div> </body> </html>