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Jankowski</h1><div class="affiliations-container fake-truncate js-profile-affiliations"><div><a class="u-tcGrayDarker" href="https://uj-pl.academia.edu/">Jagiellonian University in Krakow</a>, <a class="u-tcGrayDarker" href="https://uj-pl.academia.edu/Departments/Cardiology/Documents">Cardiology</a>, <span class="u-tcGrayDarker">Faculty Member</span></div></div></div></div><div class="sidebar-cta-container"><button class="ds2-5-button hidden profile-cta-button grow js-profile-follow-button" data-broccoli-component="user-info.follow-button" data-click-track="profile-user-info-follow-button" data-follow-user-fname="P." data-follow-user-id="33097976" data-follow-user-source="profile_button" data-has-google="false"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">add</span>Follow</button><button class="ds2-5-button hidden profile-cta-button grow js-profile-unfollow-button" data-broccoli-component="user-info.unfollow-button" 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href="https://independent.academia.edu/GiuseppeRosano">Giuseppe M C Rosano</a></div></div><div class="suggested-user-card"><div class="suggested-user-card__avatar social-profile-avatar-container"><a data-nosnippet="" href="https://independent.academia.edu/MazurArtur"><img class="profile-avatar u-positionAbsolute" alt="Artur Mazur related author profile picture" border="0" src="//a.academia-assets.com/images/s200_no_pic.png" /></a></div><div class="suggested-user-card__user-info"><a class="suggested-user-card__user-info__header ds2-5-body-sm-bold ds2-5-body-link" href="https://independent.academia.edu/MazurArtur">Artur Mazur</a></div></div><div class="suggested-user-card"><div class="suggested-user-card__avatar social-profile-avatar-container"><a data-nosnippet="" href="https://nymc.academia.edu/WilbertAronow"><img class="profile-avatar u-positionAbsolute" alt="Wilbert Aronow related author profile picture" border="0" src="//a.academia-assets.com/images/s200_no_pic.png" /></a></div><div 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class="ri-section-header"><span>Interests</span></div><div class="ri-tags-container"><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="33097976" href="https://www.academia.edu/Documents/in/Coronary_Stent"><div id="js-react-on-rails-context" style="display:none" data-rails-context="{"inMailer":false,"i18nLocale":"en","i18nDefaultLocale":"en","href":"https://uj-pl.academia.edu/PJankowski","location":"/PJankowski","scheme":"https","host":"uj-pl.academia.edu","port":null,"pathname":"/PJankowski","search":null,"httpAcceptLanguage":null,"serverSide":false}"></div> <div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Coronary Stent"]}" data-trace="false" data-dom-id="Pill-react-component-9a485892-0d52-4e76-bd15-39647fd5f933"></div> <div id="Pill-react-component-9a485892-0d52-4e76-bd15-39647fd5f933"></div> </a><a data-click-track="profile-user-info-expand-research-interests" 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class="user-content-wrapper"><div class="uploads-container" id="social-redesign-work-container"><div class="upload-header"><h2 class="ds2-5-heading-sans-serif-xs">Uploads</h2></div><div class="documents-container backbone-social-profile-documents" style="width: 100%;"><div class="u-taCenter"></div><div class="profile--tab_content_container js-tab-pane tab-pane active" id="all"><div class="profile--tab_heading_container js-section-heading" data-section="Papers" id="Papers"><h3 class="profile--tab_heading_container">Papers by P. Jankowski</h3></div><div class="js-work-strip profile--work_container" data-work-id="30659581"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/30659581/Wytyczne_PTL_KLRwP_PTK_post%C4%99powania_w_zaburzeniach_lipidowych_dla_lekarzy_rodzinnych_2016"><img alt="Research paper thumbnail of Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016" class="work-thumbnail" src="https://attachments.academia-assets.com/51102606/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/30659581/Wytyczne_PTL_KLRwP_PTK_post%C4%99powania_w_zaburzeniach_lipidowych_dla_lekarzy_rodzinnych_2016">Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://umed.academia.edu/MaciejBanach">Maciej Banach</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/BarbaraCybulska">Barbara Cybulska</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/MarlenaBroncel">Marlena Broncel</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Przez lata zaburzenia lipidowe w Polsce i na świecie nie były traktowane z należytą uwagą, a w wi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Przez lata zaburzenia lipidowe w Polsce i na świecie nie były traktowane z należytą uwagą, a w wielu przypadkach ich występowania najczęściej zalecana była dieta i zmiana stylu życia. Pomimo wielu działań edukacyjnych towarzystw medycznych w Polsce, w tym także „sygnatariuszy” niniejszych wytycznych, wiedza pacjentów na temat tego niezależnego czynnika ryzyka jest także wciąż bardzo ograniczona. W efekcie tego w Polsce mamy prawie 20 milionów osób z hipercholesterolemią. Nie istnieją kliniki zaburzeń lipidowych, a funkcjonujące poradnie najczęściej nie są dedykowane temu problemowi, ale zaburzeniom metabolicznym i/lub chorobom endokrynologicznym, a sami pacjenci nierzadko leczeni są po prostu w poradniach kardiologicznych. Wynika to także z ograniczeń systemowych, które wcale nie ułatwiają stworzenia sieci poradni lipidowych, pomimo istnienia grupy prawie 70 lekarzy lipidologów certyfikowanych przez Polskie Towarzystwo Lipidologiczne. To<br />właśnie dlatego przez lata w Polsce problem hipercholesterolemii rodzinnej (familial hypercholesterolemia– FH) nie był rozpoznawany<br />jako istotny i mało kto potrafił skojarzyć stężenia cholesterolu LDL (low density lipoprotein) >190 mg/dl (4,9 mmol/l) czy cholesterolu całkowitego 290 mg/dl (7,5 mmol/l) i więcej jako takie, których przyczyną może być choroba uwarunkowana genetycznie, i idąc dalej<br />– zakwalifikować takich pacjentów do grupy dużego i bardzo dużego ryzyka sercowo‑naczyniowego.To właśnie dlatego w Polsce leczenie<br />aferezą pacjentów z najpoważniejszymi zaburzeniami lipidowymi praktycznie nie istnieje (tylko 3 ośrodki). Tymczasem za naszą<br />zachodnią (Niemcy) czy południową (Czechy) granicą rejestr hipercholesterolemii rodzinnej tworzony jest od wielu lat, a w Niemczech liczba ośrodków wykonujących aferezy jest największa w Europie. Już kilkanaście lat temu zwrócono uwagę, że w ocenie ryzyka odległego (20‑letniego) lub tzw. lifetime risk zaburzenia lipidowe są niezależnym czynnikiem ryzyka wystąpienia incydentów sercowo‑naczyniowych, stąd ich optymalne i skuteczne leczenie jest równie ważne, jak terapia cukrzycy czy nadciśnienia tętniczego. Co więcej, nawet w przypadku<br />podjęcia leczenia dyslipidemii stoją przed nami wyzwania pod postacią niestosowania / nieprzepisywania odpowiednich dawek statyn w odniesieniu do ryzyka sercowo‑naczyniowego (co może dotyczyć nawet 80% leczonych pacjentów) czy też dyskontynuacji leczenia, braku skutecznego leczenia skojarzonego mającego na celu redukcję ryzyka rezydualnego czy też właściwego postępowania w przypadku wystąpienia działań niepożądanych związanych z leczeniem. Dlatego właśnie Polskie Towarzystwo Lipidologiczne (PTL) wraz z Kolegium Lekarzy Rodzinnych w Polsce (KLRwP) oraz Polskim Towarzystwem<br />Kardiologicznym (PTK) wspólnie zdecydowały o konieczności przygotowania pierwszych wytycznych dotyczących postępowania<br />w zaburzeniach lipidowych, dedykowanych lekarzom rodzinnym, bo to właśnie oni najczęściej po raz pierwszy diagnozują zaburzenia<br />lipidowe i to na nich w dużej mierze spoczywa odpowiedzialność za pierwsze decyzje terapeutyczne oraz kontynuację leczenia hipolipemizującego.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="72ea64663ff2a15abe84c7de1ad0ecf7" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":51102606,"asset_id":30659581,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/51102606/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="30659581"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="30659581"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 30659581; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=30659581]").text(description); $(".js-view-count[data-work-id=30659581]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 30659581; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='30659581']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "72ea64663ff2a15abe84c7de1ad0ecf7" } } $('.js-work-strip[data-work-id=30659581]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":30659581,"title":"Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016","translated_title":"","metadata":{"abstract":"Przez lata zaburzenia lipidowe w Polsce i na świecie nie były traktowane z należytą uwagą, a w wielu przypadkach ich występowania najczęściej zalecana była dieta i zmiana stylu życia. Pomimo wielu działań edukacyjnych towarzystw medycznych w Polsce, w tym także „sygnatariuszy” niniejszych wytycznych, wiedza pacjentów na temat tego niezależnego czynnika ryzyka jest także wciąż bardzo ograniczona. W efekcie tego w Polsce mamy prawie 20 milionów osób z hipercholesterolemią. Nie istnieją kliniki zaburzeń lipidowych, a funkcjonujące poradnie najczęściej nie są dedykowane temu problemowi, ale zaburzeniom metabolicznym i/lub chorobom endokrynologicznym, a sami pacjenci nierzadko leczeni są po prostu w poradniach kardiologicznych. Wynika to także z ograniczeń systemowych, które wcale nie ułatwiają stworzenia sieci poradni lipidowych, pomimo istnienia grupy prawie 70 lekarzy lipidologów certyfikowanych przez Polskie Towarzystwo Lipidologiczne. To\nwłaśnie dlatego przez lata w Polsce problem hipercholesterolemii rodzinnej (familial hypercholesterolemia– FH) nie był rozpoznawany\njako istotny i mało kto potrafił skojarzyć stężenia cholesterolu LDL (low density lipoprotein) \u003e190 mg/dl (4,9 mmol/l) czy cholesterolu całkowitego 290 mg/dl (7,5 mmol/l) i więcej jako takie, których przyczyną może być choroba uwarunkowana genetycznie, i idąc dalej\n– zakwalifikować takich pacjentów do grupy dużego i bardzo dużego ryzyka sercowo‑naczyniowego.To właśnie dlatego w Polsce leczenie\naferezą pacjentów z najpoważniejszymi zaburzeniami lipidowymi praktycznie nie istnieje (tylko 3 ośrodki). Tymczasem za naszą\nzachodnią (Niemcy) czy południową (Czechy) granicą rejestr hipercholesterolemii rodzinnej tworzony jest od wielu lat, a w Niemczech liczba ośrodków wykonujących aferezy jest największa w Europie. Już kilkanaście lat temu zwrócono uwagę, że w ocenie ryzyka odległego (20‑letniego) lub tzw. lifetime risk zaburzenia lipidowe są niezależnym czynnikiem ryzyka wystąpienia incydentów sercowo‑naczyniowych, stąd ich optymalne i skuteczne leczenie jest równie ważne, jak terapia cukrzycy czy nadciśnienia tętniczego. Co więcej, nawet w przypadku\npodjęcia leczenia dyslipidemii stoją przed nami wyzwania pod postacią niestosowania / nieprzepisywania odpowiednich dawek statyn w odniesieniu do ryzyka sercowo‑naczyniowego (co może dotyczyć nawet 80% leczonych pacjentów) czy też dyskontynuacji leczenia, braku skutecznego leczenia skojarzonego mającego na celu redukcję ryzyka rezydualnego czy też właściwego postępowania w przypadku wystąpienia działań niepożądanych związanych z leczeniem. Dlatego właśnie Polskie Towarzystwo Lipidologiczne (PTL) wraz z Kolegium Lekarzy Rodzinnych w Polsce (KLRwP) oraz Polskim Towarzystwem\nKardiologicznym (PTK) wspólnie zdecydowały o konieczności przygotowania pierwszych wytycznych dotyczących postępowania\nw zaburzeniach lipidowych, dedykowanych lekarzom rodzinnym, bo to właśnie oni najczęściej po raz pierwszy diagnozują zaburzenia\nlipidowe i to na nich w dużej mierze spoczywa odpowiedzialność za pierwsze decyzje terapeutyczne oraz kontynuację leczenia hipolipemizującego."},"translated_abstract":"Przez lata zaburzenia lipidowe w Polsce i na świecie nie były traktowane z należytą uwagą, a w wielu przypadkach ich występowania najczęściej zalecana była dieta i zmiana stylu życia. Pomimo wielu działań edukacyjnych towarzystw medycznych w Polsce, w tym także „sygnatariuszy” niniejszych wytycznych, wiedza pacjentów na temat tego niezależnego czynnika ryzyka jest także wciąż bardzo ograniczona. W efekcie tego w Polsce mamy prawie 20 milionów osób z hipercholesterolemią. Nie istnieją kliniki zaburzeń lipidowych, a funkcjonujące poradnie najczęściej nie są dedykowane temu problemowi, ale zaburzeniom metabolicznym i/lub chorobom endokrynologicznym, a sami pacjenci nierzadko leczeni są po prostu w poradniach kardiologicznych. Wynika to także z ograniczeń systemowych, które wcale nie ułatwiają stworzenia sieci poradni lipidowych, pomimo istnienia grupy prawie 70 lekarzy lipidologów certyfikowanych przez Polskie Towarzystwo Lipidologiczne. To\nwłaśnie dlatego przez lata w Polsce problem hipercholesterolemii rodzinnej (familial hypercholesterolemia– FH) nie był rozpoznawany\njako istotny i mało kto potrafił skojarzyć stężenia cholesterolu LDL (low density lipoprotein) \u003e190 mg/dl (4,9 mmol/l) czy cholesterolu całkowitego 290 mg/dl (7,5 mmol/l) i więcej jako takie, których przyczyną może być choroba uwarunkowana genetycznie, i idąc dalej\n– zakwalifikować takich pacjentów do grupy dużego i bardzo dużego ryzyka sercowo‑naczyniowego.To właśnie dlatego w Polsce leczenie\naferezą pacjentów z najpoważniejszymi zaburzeniami lipidowymi praktycznie nie istnieje (tylko 3 ośrodki). Tymczasem za naszą\nzachodnią (Niemcy) czy południową (Czechy) granicą rejestr hipercholesterolemii rodzinnej tworzony jest od wielu lat, a w Niemczech liczba ośrodków wykonujących aferezy jest największa w Europie. Już kilkanaście lat temu zwrócono uwagę, że w ocenie ryzyka odległego (20‑letniego) lub tzw. lifetime risk zaburzenia lipidowe są niezależnym czynnikiem ryzyka wystąpienia incydentów sercowo‑naczyniowych, stąd ich optymalne i skuteczne leczenie jest równie ważne, jak terapia cukrzycy czy nadciśnienia tętniczego. Co więcej, nawet w przypadku\npodjęcia leczenia dyslipidemii stoją przed nami wyzwania pod postacią niestosowania / nieprzepisywania odpowiednich dawek statyn w odniesieniu do ryzyka sercowo‑naczyniowego (co może dotyczyć nawet 80% leczonych pacjentów) czy też dyskontynuacji leczenia, braku skutecznego leczenia skojarzonego mającego na celu redukcję ryzyka rezydualnego czy też właściwego postępowania w przypadku wystąpienia działań niepożądanych związanych z leczeniem. Dlatego właśnie Polskie Towarzystwo Lipidologiczne (PTL) wraz z Kolegium Lekarzy Rodzinnych w Polsce (KLRwP) oraz Polskim Towarzystwem\nKardiologicznym (PTK) wspólnie zdecydowały o konieczności przygotowania pierwszych wytycznych dotyczących postępowania\nw zaburzeniach lipidowych, dedykowanych lekarzom rodzinnym, bo to właśnie oni najczęściej po raz pierwszy diagnozują zaburzenia\nlipidowe i to na nich w dużej mierze spoczywa odpowiedzialność za pierwsze decyzje terapeutyczne oraz kontynuację leczenia hipolipemizującego.","internal_url":"https://www.academia.edu/30659581/Wytyczne_PTL_KLRwP_PTK_post%C4%99powania_w_zaburzeniach_lipidowych_dla_lekarzy_rodzinnych_2016","translated_internal_url":"","created_at":"2016-12-29T01:39:29.563-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":781527,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":26818349,"work_id":30659581,"tagging_user_id":781527,"tagged_user_id":33097976,"co_author_invite_id":null,"email":"p***i@interia.pl","affiliation":"Jagiellonian University in Krakow","display_order":1,"name":"P. Jankowski","title":"Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016"},{"id":26818350,"work_id":30659581,"tagging_user_id":781527,"tagged_user_id":58427629,"co_author_invite_id":1072776,"email":"j***k@sla.pl","display_order":2,"name":"Jacek Jóźwiak","title":"Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016"},{"id":26818351,"work_id":30659581,"tagging_user_id":781527,"tagged_user_id":36507410,"co_author_invite_id":null,"email":"b***a@wp.pl","display_order":3,"name":"Barbara Cybulska","title":"Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016"},{"id":26818352,"work_id":30659581,"tagging_user_id":781527,"tagged_user_id":null,"co_author_invite_id":414609,"email":"m***k@cyf-kr.edu.pl","display_order":4,"name":"Adam Windak","title":"Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016"},{"id":26818353,"work_id":30659581,"tagging_user_id":781527,"tagged_user_id":3044646,"co_author_invite_id":null,"email":"t***k@yahoo.com","affiliation":"Jagiellonian University","display_order":5,"name":"Tomasz Guzik","title":"Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016"},{"id":26818354,"work_id":30659581,"tagging_user_id":781527,"tagged_user_id":37207463,"co_author_invite_id":null,"email":"a***z@wum.edu.pl","display_order":6,"name":"Artur Mamcarz","title":"Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016"},{"id":26818355,"work_id":30659581,"tagging_user_id":781527,"tagged_user_id":58413595,"co_author_invite_id":5901923,"email":"m***l@umed.lodz.pl","display_order":7,"name":"Marlena Broncel","title":"Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016"},{"id":26818356,"work_id":30659581,"tagging_user_id":781527,"tagged_user_id":58578858,"co_author_invite_id":5901924,"email":"m***i@cyf-kr.edu.pl","display_order":8,"name":"Tomasz Tomasik","title":"Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016"},{"id":26958943,"work_id":30659581,"tagging_user_id":58413595,"tagged_user_id":null,"co_author_invite_id":5927999,"email":"s***a@termedia.pl","display_order":4194308,"name":"Konferencje Termedia","title":"Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016"}],"downloadable_attachments":[{"id":51102606,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/51102606/thumbnails/1.jpg","file_name":"LPOZ_Art_28951-10.pdf","download_url":"https://www.academia.edu/attachments/51102606/download_file","bulk_download_file_name":"Wytyczne_PTL_KLRwP_PTK_postepowania_w_za.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/51102606/LPOZ_Art_28951-10-libre.pdf?1483004525=\u0026response-content-disposition=attachment%3B+filename%3DWytyczne_PTL_KLRwP_PTK_postepowania_w_za.pdf\u0026Expires=1743642920\u0026Signature=Q-QEQgQ96~JBB29brJ-FybW7mGurtcpIMvFOjiGHrWcBPxtu~YeQqoHwMnVVTgUQ3-X~7VqKtdI60cBPfR9SsX3sTYdryXOdQNeL-YR09AVER91L6CvJAxDv8NttOf6ZHKrjevfD5gJZQdyj~Ikv4hPIOYGL8x9jfESJ-dxVuhJ-6vaOxRUL9Morc0urzDWSy-TQ-ZUHYhej83IBhmMvoqiXZc84Filq-qtzDKt2hm60UjUGZoxDesYgH9s04BsQ1QFCyfuQhyyWIIbhfwoJi~MyTK72oAwUrvOPVK0rgHYrJVPeShAj5TuSDtT-~HQDjSlevv3X-2WWGf9idigD9Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Wytyczne_PTL_KLRwP_PTK_postępowania_w_zaburzeniach_lipidowych_dla_lekarzy_rodzinnych_2016","translated_slug":"","page_count":50,"language":"pl","content_type":"Work","summary":"Przez lata zaburzenia lipidowe w Polsce i na świecie nie były traktowane z należytą uwagą, a w wielu przypadkach ich występowania najczęściej zalecana była dieta i zmiana stylu życia. Pomimo wielu działań edukacyjnych towarzystw medycznych w Polsce, w tym także „sygnatariuszy” niniejszych wytycznych, wiedza pacjentów na temat tego niezależnego czynnika ryzyka jest także wciąż bardzo ograniczona. W efekcie tego w Polsce mamy prawie 20 milionów osób z hipercholesterolemią. Nie istnieją kliniki zaburzeń lipidowych, a funkcjonujące poradnie najczęściej nie są dedykowane temu problemowi, ale zaburzeniom metabolicznym i/lub chorobom endokrynologicznym, a sami pacjenci nierzadko leczeni są po prostu w poradniach kardiologicznych. Wynika to także z ograniczeń systemowych, które wcale nie ułatwiają stworzenia sieci poradni lipidowych, pomimo istnienia grupy prawie 70 lekarzy lipidologów certyfikowanych przez Polskie Towarzystwo Lipidologiczne. To\nwłaśnie dlatego przez lata w Polsce problem hipercholesterolemii rodzinnej (familial hypercholesterolemia– FH) nie był rozpoznawany\njako istotny i mało kto potrafił skojarzyć stężenia cholesterolu LDL (low density lipoprotein) \u003e190 mg/dl (4,9 mmol/l) czy cholesterolu całkowitego 290 mg/dl (7,5 mmol/l) i więcej jako takie, których przyczyną może być choroba uwarunkowana genetycznie, i idąc dalej\n– zakwalifikować takich pacjentów do grupy dużego i bardzo dużego ryzyka sercowo‑naczyniowego.To właśnie dlatego w Polsce leczenie\naferezą pacjentów z najpoważniejszymi zaburzeniami lipidowymi praktycznie nie istnieje (tylko 3 ośrodki). Tymczasem za naszą\nzachodnią (Niemcy) czy południową (Czechy) granicą rejestr hipercholesterolemii rodzinnej tworzony jest od wielu lat, a w Niemczech liczba ośrodków wykonujących aferezy jest największa w Europie. Już kilkanaście lat temu zwrócono uwagę, że w ocenie ryzyka odległego (20‑letniego) lub tzw. lifetime risk zaburzenia lipidowe są niezależnym czynnikiem ryzyka wystąpienia incydentów sercowo‑naczyniowych, stąd ich optymalne i skuteczne leczenie jest równie ważne, jak terapia cukrzycy czy nadciśnienia tętniczego. Co więcej, nawet w przypadku\npodjęcia leczenia dyslipidemii stoją przed nami wyzwania pod postacią niestosowania / nieprzepisywania odpowiednich dawek statyn w odniesieniu do ryzyka sercowo‑naczyniowego (co może dotyczyć nawet 80% leczonych pacjentów) czy też dyskontynuacji leczenia, braku skutecznego leczenia skojarzonego mającego na celu redukcję ryzyka rezydualnego czy też właściwego postępowania w przypadku wystąpienia działań niepożądanych związanych z leczeniem. Dlatego właśnie Polskie Towarzystwo Lipidologiczne (PTL) wraz z Kolegium Lekarzy Rodzinnych w Polsce (KLRwP) oraz Polskim Towarzystwem\nKardiologicznym (PTK) wspólnie zdecydowały o konieczności przygotowania pierwszych wytycznych dotyczących postępowania\nw zaburzeniach lipidowych, dedykowanych lekarzom rodzinnym, bo to właśnie oni najczęściej po raz pierwszy diagnozują zaburzenia\nlipidowe i to na nich w dużej mierze spoczywa odpowiedzialność za pierwsze decyzje terapeutyczne oraz kontynuację leczenia hipolipemizującego.","owner":{"id":781527,"first_name":"Maciej","middle_initials":null,"last_name":"Banach","page_name":"MaciejBanach","domain_name":"umed","created_at":"2011-09-23T06:49:52.933-07:00","display_name":"Maciej Banach","url":"https://umed.academia.edu/MaciejBanach"},"attachments":[{"id":51102606,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/51102606/thumbnails/1.jpg","file_name":"LPOZ_Art_28951-10.pdf","download_url":"https://www.academia.edu/attachments/51102606/download_file","bulk_download_file_name":"Wytyczne_PTL_KLRwP_PTK_postepowania_w_za.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/51102606/LPOZ_Art_28951-10-libre.pdf?1483004525=\u0026response-content-disposition=attachment%3B+filename%3DWytyczne_PTL_KLRwP_PTK_postepowania_w_za.pdf\u0026Expires=1743642920\u0026Signature=Q-QEQgQ96~JBB29brJ-FybW7mGurtcpIMvFOjiGHrWcBPxtu~YeQqoHwMnVVTgUQ3-X~7VqKtdI60cBPfR9SsX3sTYdryXOdQNeL-YR09AVER91L6CvJAxDv8NttOf6ZHKrjevfD5gJZQdyj~Ikv4hPIOYGL8x9jfESJ-dxVuhJ-6vaOxRUL9Morc0urzDWSy-TQ-ZUHYhej83IBhmMvoqiXZc84Filq-qtzDKt2hm60UjUGZoxDesYgH9s04BsQ1QFCyfuQhyyWIIbhfwoJi~MyTK72oAwUrvOPVK0rgHYrJVPeShAj5TuSDtT-~HQDjSlevv3X-2WWGf9idigD9Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":2974,"name":"Primary Health Care","url":"https://www.academia.edu/Documents/in/Primary_Health_Care"},{"id":52055,"name":"Lipids","url":"https://www.academia.edu/Documents/in/Lipids"},{"id":167643,"name":"Statins","url":"https://www.academia.edu/Documents/in/Statins"},{"id":227278,"name":"Atherogenic Dyslipidemia","url":"https://www.academia.edu/Documents/in/Atherogenic_Dyslipidemia"},{"id":235465,"name":"Guidelines","url":"https://www.academia.edu/Documents/in/Guidelines"},{"id":333996,"name":"Recommendations","url":"https://www.academia.edu/Documents/in/Recommendations"},{"id":437953,"name":"Dyslipidemia","url":"https://www.academia.edu/Documents/in/Dyslipidemia"},{"id":1157351,"name":"Primary Health Centre","url":"https://www.academia.edu/Documents/in/Primary_Health_Centre"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-30659581-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="30659717"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/30659717/PoLA_CFPiP_PCS_Guidelines_for_the_Management_of_Dyslipidaemias_for_Family_Physicians_2016"><img alt="Research paper thumbnail of PoLA/CFPiP/PCS Guidelines for the Management of Dyslipidaemias for Family Physicians 2016" class="work-thumbnail" src="https://attachments.academia-assets.com/51102721/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/30659717/PoLA_CFPiP_PCS_Guidelines_for_the_Management_of_Dyslipidaemias_for_Family_Physicians_2016">PoLA/CFPiP/PCS Guidelines for the Management of Dyslipidaemias for Family Physicians 2016</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://umed.academia.edu/MaciejBanach">Maciej Banach</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/JacekJ%C3%B3%C5%BAwiak">Jacek Jóźwiak</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/BarbaraCybulska">Barbara Cybulska</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/MarlenaBroncel">Marlena Broncel</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">For many years, dyslipidaemias failed to receive the attention they deserve, both in Poland and a...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">For many years, dyslipidaemias failed to receive the attention they deserve, both in Poland and across the world. In many cases, the most common recommendation given to patients suffering from lipid disorders was to change their diet and lifestyle. Despite multiple educational efforts undertaken by medical societies in Poland, including the signatories of the Guidelines, the knowledge of patients about this independent risk factor continues to be very limited even today. As a result, there are nearly 20 million hypercholesterolaemic patients in Poland. Furthermore, there are no medical (lipid) clinics specializing in<br />the treatment of lipid disorders, and existing outpatient clinics are not usually dedicated specifically to dyslipidaemias, but metabolic disorders<br />and/or endocrine conditions. Not uncommonly, patients receive treatment in cardiac outpatient clinics. The existing state of affairs stems partly from systemic constraints, which pose a hindrance to the establishment of a network of lipid outpatient clinics – even though a total of 70 lipidologists have already been certified by the Polish Lipid Association (PoLA). This is precisely why the problem of familial hypercholesterolaemia (FH) in Poland was not recognized as significant for many years. Few physicians were able to consider low density lipoprotein cholesterol (LDL-C) concentrations in excess of 190 mg/dl (4.9 mmol/l) or total cholesterol (TC) concentrations of 290 mg/dl (7.5<br />mmol/l) and more as potentially caused by genetically conditioned disease and, taking the matter further, classify patients presenting with such disorders into high and very high cardiovascular risk groups. This is why the treatment of patients with the most severe lipid disorders with apheresis is practically non-existent in Poland, with only three treatment centres available to patients. In contrast, in neighbouring countries (Germany, Czech Republic), nationwide FH registries have been kept for many years. Germany, in addition, has the largest number of medical centres offering apheresis treatment in Europe. It was first noted about a dozen years ago in the estimation of long-term (20-year) risk or lifetime<br />risk that dyslipidaemias represented an independent risk factor for cardiovascular (CV) events. It thus follows that optimal effective treatment of lipid disorders is as important as the therapy of diabetes<br />or arterial hypertension. What is more, even if dyslipidaemia treatment is undertaken, further challenges must be faced such as failure to use/prescribe statins at doses corresponding to the level of CV risk (the situation may affect as much as 80% of all treated patients), discontinuation of therapy, lack of effective combination treatment aimed at reducing residual risk or failure to ensure appropriate management of undesirable treatment-related effects.<br /><br />In view of the situation outlined above, the PoLA, the College of Family Physicians in Poland (CFPiP) and the Polish Cardiac Society (PCS) have<br />jointly identified a need to draft the first guidelines regulating the management of dyslipidaemias and addressed to family physicians, as they are usually the first to diagnose lipid disorders and they are largely responsible for the initial therapeutic decisions and for the continuation of lipid-lowering therapy (LLT).</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="71f5dcda11b436de5a62c6151163042c" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":51102721,"asset_id":30659717,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/51102721/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="30659717"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="30659717"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 30659717; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=30659717]").text(description); $(".js-view-count[data-work-id=30659717]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 30659717; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='30659717']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "71f5dcda11b436de5a62c6151163042c" } } $('.js-work-strip[data-work-id=30659717]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":30659717,"title":"PoLA/CFPiP/PCS Guidelines for the Management of Dyslipidaemias for Family Physicians 2016","translated_title":"","metadata":{"abstract":"For many years, dyslipidaemias failed to receive the attention they deserve, both in Poland and across the world. In many cases, the most common recommendation given to patients suffering from lipid disorders was to change their diet and lifestyle. Despite multiple educational efforts undertaken by medical societies in Poland, including the signatories of the Guidelines, the knowledge of patients about this independent risk factor continues to be very limited even today. As a result, there are nearly 20 million hypercholesterolaemic patients in Poland. Furthermore, there are no medical (lipid) clinics specializing in\nthe treatment of lipid disorders, and existing outpatient clinics are not usually dedicated specifically to dyslipidaemias, but metabolic disorders\nand/or endocrine conditions. Not uncommonly, patients receive treatment in cardiac outpatient clinics. The existing state of affairs stems partly from systemic constraints, which pose a hindrance to the establishment of a network of lipid outpatient clinics – even though a total of 70 lipidologists have already been certified by the Polish Lipid Association (PoLA). This is precisely why the problem of familial hypercholesterolaemia (FH) in Poland was not recognized as significant for many years. Few physicians were able to consider low density lipoprotein cholesterol (LDL-C) concentrations in excess of 190 mg/dl (4.9 mmol/l) or total cholesterol (TC) concentrations of 290 mg/dl (7.5\nmmol/l) and more as potentially caused by genetically conditioned disease and, taking the matter further, classify patients presenting with such disorders into high and very high cardiovascular risk groups. This is why the treatment of patients with the most severe lipid disorders with apheresis is practically non-existent in Poland, with only three treatment centres available to patients. In contrast, in neighbouring countries (Germany, Czech Republic), nationwide FH registries have been kept for many years. Germany, in addition, has the largest number of medical centres offering apheresis treatment in Europe. It was first noted about a dozen years ago in the estimation of long-term (20-year) risk or lifetime\nrisk that dyslipidaemias represented an independent risk factor for cardiovascular (CV) events. It thus follows that optimal effective treatment of lipid disorders is as important as the therapy of diabetes\nor arterial hypertension. What is more, even if dyslipidaemia treatment is undertaken, further challenges must be faced such as failure to use/prescribe statins at doses corresponding to the level of CV risk (the situation may affect as much as 80% of all treated patients), discontinuation of therapy, lack of effective combination treatment aimed at reducing residual risk or failure to ensure appropriate management of undesirable treatment-related effects.\n\nIn view of the situation outlined above, the PoLA, the College of Family Physicians in Poland (CFPiP) and the Polish Cardiac Society (PCS) have\njointly identified a need to draft the first guidelines regulating the management of dyslipidaemias and addressed to family physicians, as they are usually the first to diagnose lipid disorders and they are largely responsible for the initial therapeutic decisions and for the continuation of lipid-lowering therapy (LLT)."},"translated_abstract":"For many years, dyslipidaemias failed to receive the attention they deserve, both in Poland and across the world. In many cases, the most common recommendation given to patients suffering from lipid disorders was to change their diet and lifestyle. Despite multiple educational efforts undertaken by medical societies in Poland, including the signatories of the Guidelines, the knowledge of patients about this independent risk factor continues to be very limited even today. As a result, there are nearly 20 million hypercholesterolaemic patients in Poland. Furthermore, there are no medical (lipid) clinics specializing in\nthe treatment of lipid disorders, and existing outpatient clinics are not usually dedicated specifically to dyslipidaemias, but metabolic disorders\nand/or endocrine conditions. Not uncommonly, patients receive treatment in cardiac outpatient clinics. The existing state of affairs stems partly from systemic constraints, which pose a hindrance to the establishment of a network of lipid outpatient clinics – even though a total of 70 lipidologists have already been certified by the Polish Lipid Association (PoLA). This is precisely why the problem of familial hypercholesterolaemia (FH) in Poland was not recognized as significant for many years. Few physicians were able to consider low density lipoprotein cholesterol (LDL-C) concentrations in excess of 190 mg/dl (4.9 mmol/l) or total cholesterol (TC) concentrations of 290 mg/dl (7.5\nmmol/l) and more as potentially caused by genetically conditioned disease and, taking the matter further, classify patients presenting with such disorders into high and very high cardiovascular risk groups. This is why the treatment of patients with the most severe lipid disorders with apheresis is practically non-existent in Poland, with only three treatment centres available to patients. In contrast, in neighbouring countries (Germany, Czech Republic), nationwide FH registries have been kept for many years. Germany, in addition, has the largest number of medical centres offering apheresis treatment in Europe. It was first noted about a dozen years ago in the estimation of long-term (20-year) risk or lifetime\nrisk that dyslipidaemias represented an independent risk factor for cardiovascular (CV) events. It thus follows that optimal effective treatment of lipid disorders is as important as the therapy of diabetes\nor arterial hypertension. What is more, even if dyslipidaemia treatment is undertaken, further challenges must be faced such as failure to use/prescribe statins at doses corresponding to the level of CV risk (the situation may affect as much as 80% of all treated patients), discontinuation of therapy, lack of effective combination treatment aimed at reducing residual risk or failure to ensure appropriate management of undesirable treatment-related effects.\n\nIn view of the situation outlined above, the PoLA, the College of Family Physicians in Poland (CFPiP) and the Polish Cardiac Society (PCS) have\njointly identified a need to draft the first guidelines regulating the management of dyslipidaemias and addressed to family physicians, as they are usually the first to diagnose lipid disorders and they are largely responsible for the initial therapeutic decisions and for the continuation of lipid-lowering therapy (LLT).","internal_url":"https://www.academia.edu/30659717/PoLA_CFPiP_PCS_Guidelines_for_the_Management_of_Dyslipidaemias_for_Family_Physicians_2016","translated_internal_url":"","created_at":"2016-12-29T01:52:57.799-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":781527,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":26818400,"work_id":30659717,"tagging_user_id":781527,"tagged_user_id":781527,"co_author_invite_id":5901942,"email":"m***h@aol.co.uk","affiliation":"Medical University of Lodz, Lodz, Poland","display_order":1,"name":"Maciej Banach","title":"PoLA/CFPiP/PCS Guidelines for the Management of Dyslipidaemias for Family Physicians 2016"},{"id":26818401,"work_id":30659717,"tagging_user_id":781527,"tagged_user_id":33097976,"co_author_invite_id":null,"email":"p***i@interia.pl","affiliation":"Jagiellonian University in Krakow","display_order":2,"name":"P. 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The existing state of affairs stems partly from systemic constraints, which pose a hindrance to the establishment of a network of lipid outpatient clinics – even though a total of 70 lipidologists have already been certified by the Polish Lipid Association (PoLA). This is precisely why the problem of familial hypercholesterolaemia (FH) in Poland was not recognized as significant for many years. Few physicians were able to consider low density lipoprotein cholesterol (LDL-C) concentrations in excess of 190 mg/dl (4.9 mmol/l) or total cholesterol (TC) concentrations of 290 mg/dl (7.5\nmmol/l) and more as potentially caused by genetically conditioned disease and, taking the matter further, classify patients presenting with such disorders into high and very high cardiovascular risk groups. This is why the treatment of patients with the most severe lipid disorders with apheresis is practically non-existent in Poland, with only three treatment centres available to patients. In contrast, in neighbouring countries (Germany, Czech Republic), nationwide FH registries have been kept for many years. Germany, in addition, has the largest number of medical centres offering apheresis treatment in Europe. It was first noted about a dozen years ago in the estimation of long-term (20-year) risk or lifetime\nrisk that dyslipidaemias represented an independent risk factor for cardiovascular (CV) events. It thus follows that optimal effective treatment of lipid disorders is as important as the therapy of diabetes\nor arterial hypertension. What is more, even if dyslipidaemia treatment is undertaken, further challenges must be faced such as failure to use/prescribe statins at doses corresponding to the level of CV risk (the situation may affect as much as 80% of all treated patients), discontinuation of therapy, lack of effective combination treatment aimed at reducing residual risk or failure to ensure appropriate management of undesirable treatment-related effects.\n\nIn view of the situation outlined above, the PoLA, the College of Family Physicians in Poland (CFPiP) and the Polish Cardiac Society (PCS) have\njointly identified a need to draft the first guidelines regulating the management of dyslipidaemias and addressed to family physicians, as they are usually the first to diagnose lipid disorders and they are largely responsible for the initial therapeutic decisions and for the continuation of lipid-lowering therapy (LLT).","owner":{"id":781527,"first_name":"Maciej","middle_initials":null,"last_name":"Banach","page_name":"MaciejBanach","domain_name":"umed","created_at":"2011-09-23T06:49:52.933-07:00","display_name":"Maciej Banach","url":"https://umed.academia.edu/MaciejBanach"},"attachments":[{"id":51102721,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/51102721/thumbnails/1.jpg","file_name":"AOMS_Art_28931-10.pdf","download_url":"https://www.academia.edu/attachments/51102721/download_file","bulk_download_file_name":"PoLA_CFPiP_PCS_Guidelines_for_the_Manage.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/51102721/AOMS_Art_28931-10-libre.pdf?1483005146=\u0026response-content-disposition=attachment%3B+filename%3DPoLA_CFPiP_PCS_Guidelines_for_the_Manage.pdf\u0026Expires=1743615394\u0026Signature=RZNHHF2cDd8QL1LS3eK~CkT7-bmYsuXr1XaPJcSToTmoSfKwGKfrWA2onLMqX8gQBxrmPfyGEkIvmHeWg62s6HuwSH5j~Xczd9-8DU-5ZPn-Goo1J71mDKR5tqSRbXmRlullKruKWo8LJNIu~Rlo0-xQ7qRMPKl92gmrGQwf-WjdfZ634zRCC~lditmQFBIOHm0ntPN5m6FjFE273YB-Uz1w3~18P~rXCiyFawjb997lFcIugIZM6mwcs5sU2VE2CyyLXedJpQ6oGXd9LzJaieZvb1hsiPB7GPDdSYpBmuySQCeC5cColuO-WDT~ni8Jbe9eTeTyF~NM58f5-dQ93Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":231,"name":"Family Therapy","url":"https://www.academia.edu/Documents/in/Family_Therapy"},{"id":2302,"name":"Nutraceuticals","url":"https://www.academia.edu/Documents/in/Nutraceuticals"},{"id":167643,"name":"Statins","url":"https://www.academia.edu/Documents/in/Statins"},{"id":227287,"name":"Athreogenic Dyslipidemia","url":"https://www.academia.edu/Documents/in/Athreogenic_Dyslipidemia"},{"id":235465,"name":"Guidelines","url":"https://www.academia.edu/Documents/in/Guidelines"},{"id":333996,"name":"Recommendations","url":"https://www.academia.edu/Documents/in/Recommendations"},{"id":437953,"name":"Dyslipidemia","url":"https://www.academia.edu/Documents/in/Dyslipidemia"},{"id":957647,"name":"Fibrates","url":"https://www.academia.edu/Documents/in/Fibrates"},{"id":1954133,"name":"PCSK9","url":"https://www.academia.edu/Documents/in/PCSK9"},{"id":2164652,"name":"Ezetimibe","url":"https://www.academia.edu/Documents/in/Ezetimibe"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-30659717-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="15140595"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/15140595/Changes_in_secondary_prevention_of_coronary_artery_disease_in_the_post_discharge_period_over_the_decade_1997_2007_Results_of_the_Cracovian_Program_for_Secondary_Prevention_of_Ischaemic_Heart_Disease_and_Polish_parts_of_the_EUROASPIRE_II_and_III_surveys"><img alt="Research paper thumbnail of Changes in secondary prevention of coronary artery disease in the post-discharge period over the decade 1997-2007. Results of the Cracovian Program for Secondary Prevention of Ischaemic Heart Disease and Polish parts of the EUROASPIRE II and III surveys" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title">Changes in secondary prevention of coronary artery disease in the post-discharge period over the decade 1997-2007. Results of the Cracovian Program for Secondary Prevention of Ischaemic Heart Disease and Polish parts of the EUROASPIRE II and III surveys</div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/S%C5%82awomirSurowiec">Sławomir Surowiec</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a></span></div><div class="wp-workCard_item"><span>Kardiologia polska</span><span>, 2009</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Both in the European and Polish guidelines, the highest priority for preventive cardiology was gi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Both in the European and Polish guidelines, the highest priority for preventive cardiology was given to patients with established coronary artery disease (CAD). The Cracovian Program for Secondary Prevention of Ischaemic Heart Disease was introduced in 1996 to assess and improve the quality of clinical care in secondary prevention. Departments of cardiology of five participating hospitals serving the area of the city of Kraków and surrounding districts (former Kraków Voivodship) inhabited by a population of 1 200 000 took part in the surveys. In 1999/2000 and 2006/2007 the same hospitals joined the EUROASPIRE (European Action on Secondary Prevention through Intervention to Reduce Events) II and III surveys. The goal of the EUROASPIRE surveys was to assess to what extent the recommendations of the Joint Task Force of International Scientific Societies were implemented into clinical practice. To compare the quality of secondary prevention in the post-discharge period in Kraków in 1997...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="15140595"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="15140595"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 15140595; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=15140595]").text(description); $(".js-view-count[data-work-id=15140595]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 15140595; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='15140595']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=15140595]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":15140595,"title":"Changes in secondary prevention of coronary artery disease in the post-discharge period over the decade 1997-2007. 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In 1999/2000 and 2006/2007 the same hospitals joined the EUROASPIRE (European Action on Secondary Prevention through Intervention to Reduce Events) II and III surveys. The goal of the EUROASPIRE surveys was to assess to what extent the recommendations of the Joint Task Force of International Scientific Societies were implemented into clinical practice. 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Results of the Cracovian Program for Secondary Prevention of Ischaemic Heart Disease and Polish parts of the EUROASPIRE II and III surveys"}],"downloadable_attachments":[],"slug":"Changes_in_secondary_prevention_of_coronary_artery_disease_in_the_post_discharge_period_over_the_decade_1997_2007_Results_of_the_Cracovian_Program_for_Secondary_Prevention_of_Ischaemic_Heart_Disease_and_Polish_parts_of_the_EUROASPIRE_II_and_III_surveys","translated_slug":"","page_count":null,"language":"en","content_type":"Work","summary":"Both in the European and Polish guidelines, the highest priority for preventive cardiology was given to patients with established coronary artery disease (CAD). The Cracovian Program for Secondary Prevention of Ischaemic Heart Disease was introduced in 1996 to assess and improve the quality of clinical care in secondary prevention. Departments of cardiology of five participating hospitals serving the area of the city of Kraków and surrounding districts (former Kraków Voivodship) inhabited by a population of 1 200 000 took part in the surveys. In 1999/2000 and 2006/2007 the same hospitals joined the EUROASPIRE (European Action on Secondary Prevention through Intervention to Reduce Events) II and III surveys. The goal of the EUROASPIRE surveys was to assess to what extent the recommendations of the Joint Task Force of International Scientific Societies were implemented into clinical practice. To compare the quality of secondary prevention in the post-discharge period in Kraków in 1997...","owner":{"id":34178405,"first_name":"Sławomir","middle_initials":"","last_name":"Surowiec","page_name":"SławomirSurowiec","domain_name":"independent","created_at":"2015-08-24T03:48:31.118-07:00","display_name":"Sławomir Surowiec","url":"https://independent.academia.edu/S%C5%82awomirSurowiec"},"attachments":[],"research_interests":[{"id":7471,"name":"Life Style","url":"https://www.academia.edu/Documents/in/Life_Style"},{"id":27363,"name":"Poland","url":"https://www.academia.edu/Documents/in/Poland"},{"id":28973,"name":"Comorbidity","url":"https://www.academia.edu/Documents/in/Comorbidity"},{"id":130343,"name":"Hypercholesterolemia","url":"https://www.academia.edu/Documents/in/Hypercholesterolemia"},{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies"},{"id":167876,"name":"Myocardial Revascularization","url":"https://www.academia.edu/Documents/in/Myocardial_Revascularization"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":789977,"name":"Coronary Artery Disease","url":"https://www.academia.edu/Documents/in/Coronary_Artery_Disease"},{"id":1200766,"name":"Drug Utilization","url":"https://www.academia.edu/Documents/in/Drug_Utilization"},{"id":1246554,"name":"SECONDARY PREVENTION","url":"https://www.academia.edu/Documents/in/SECONDARY_PREVENTION"},{"id":1786368,"name":"Kardiologia","url":"https://www.academia.edu/Documents/in/Kardiologia"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-15140595-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="15140592"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/15140592/Half_of_coronary_patients_are_not_instructed_how_to_respond_to_symptoms_of_a_heart_attack"><img alt="Research paper thumbnail of Half of coronary patients are not instructed how to respond to symptoms of a heart attack" class="work-thumbnail" src="https://attachments.academia-assets.com/43538921/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/15140592/Half_of_coronary_patients_are_not_instructed_how_to_respond_to_symptoms_of_a_heart_attack">Half of coronary patients are not instructed how to respond to symptoms of a heart attack</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/S%C5%82awomirSurowiec">Sławomir Surowiec</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a></span></div><div class="wp-workCard_item"><span>Cardiology Journal</span><span>, 2011</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The delayed treatment of acute coronary syndrome has a significant impact on survival. Due to imp...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The delayed treatment of acute coronary syndrome has a significant impact on survival. Due to improved organization and the use of reperfusion therapies, inhospital delay has been shortened in recent years. However, the time between the onset of chest pain and the call for medical help is still too long. The aim of this study was to assess the proportion of coronary patients instructed how to behave in case of chest pain and to find what factors relate to a lower probability of being counselled.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="7bbfb6129b6056dd35a55080d30e32d4" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":43538921,"asset_id":15140592,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/43538921/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="15140592"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="15140592"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 15140592; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=15140592]").text(description); $(".js-view-count[data-work-id=15140592]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 15140592; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='15140592']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "7bbfb6129b6056dd35a55080d30e32d4" } } $('.js-work-strip[data-work-id=15140592]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":15140592,"title":"Half of coronary patients are not instructed how to respond to symptoms of a heart attack","translated_title":"","metadata":{"ai_title_tag":"Many Coronary Patients Lack Guidance on Heart Attack Response","grobid_abstract":"The delayed treatment of acute coronary syndrome has a significant impact on survival. Due to improved organization and the use of reperfusion therapies, inhospital delay has been shortened in recent years. However, the time between the onset of chest pain and the call for medical help is still too long. The aim of this study was to assess the proportion of coronary patients instructed how to behave in case of chest pain and to find what factors relate to a lower probability of being counselled.","publication_date":{"day":null,"month":null,"year":2011,"errors":{}},"publication_name":"Cardiology Journal","grobid_abstract_attachment_id":43538921},"translated_abstract":null,"internal_url":"https://www.academia.edu/15140592/Half_of_coronary_patients_are_not_instructed_how_to_respond_to_symptoms_of_a_heart_attack","translated_internal_url":"","created_at":"2015-08-24T03:49:07.838-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":34178405,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":4985776,"work_id":15140592,"tagging_user_id":34178405,"tagged_user_id":33097976,"co_author_invite_id":null,"email":"p***i@interia.pl","affiliation":"Jagiellonian University in Krakow","display_order":0,"name":"P. Jankowski","title":"Half of coronary patients are not instructed how to respond to symptoms of a heart attack"},{"id":4985782,"work_id":15140592,"tagging_user_id":34178405,"tagged_user_id":null,"co_author_invite_id":787307,"email":"m***k@cyf-kr.edu.pl","display_order":4194304,"name":"Kalina Kawecka-jaszcz","title":"Half of coronary patients are not instructed how to respond to symptoms of a heart attack"}],"downloadable_attachments":[{"id":43538921,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/43538921/thumbnails/1.jpg","file_name":"Half_of_coronary_patients_are_not_instru20160309-24861-16rucda.pdf","download_url":"https://www.academia.edu/attachments/43538921/download_file","bulk_download_file_name":"Half_of_coronary_patients_are_not_instru.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/43538921/Half_of_coronary_patients_are_not_instru20160309-24861-16rucda-libre.pdf?1457521559=\u0026response-content-disposition=attachment%3B+filename%3DHalf_of_coronary_patients_are_not_instru.pdf\u0026Expires=1743675856\u0026Signature=Ocvc8vY4rdNRUFHjNWJZlMjH3ynN~J1jEfsIZFGpde7spXV0Sr6Q4PCl-t8utTEULS5TsW3j7krZWmRl5NbyEMNTWLHP67EpfK7rNnEJrMsFFCbyThFT747f7MRqQY0Mp2tEsici0vJ5hoTZqun44qc-bHchqJqsZ-v9mj16XNSLfuzwxod0anN7u5Z-FC6CWn93K5K9f3W~enfa0qEoaDtoPYoLMe2IT80gpBqcMH~AKPZjxdmO19s3Is1LG7flNLMkycgXKXb7ioLsVLO27uAOswgR1Auwg9ETMe~5~nr9~mGQoR02k9Xpv3uL1cOyKbr41RJdQioCyKXoqJZx1g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Half_of_coronary_patients_are_not_instructed_how_to_respond_to_symptoms_of_a_heart_attack","translated_slug":"","page_count":7,"language":"en","content_type":"Work","summary":"The delayed treatment of acute coronary syndrome has a significant impact on survival. Due to improved organization and the use of reperfusion therapies, inhospital delay has been shortened in recent years. However, the time between the onset of chest pain and the call for medical help is still too long. The aim of this study was to assess the proportion of coronary patients instructed how to behave in case of chest pain and to find what factors relate to a lower probability of being counselled.","owner":{"id":34178405,"first_name":"Sławomir","middle_initials":"","last_name":"Surowiec","page_name":"SławomirSurowiec","domain_name":"independent","created_at":"2015-08-24T03:48:31.118-07:00","display_name":"Sławomir Surowiec","url":"https://independent.academia.edu/S%C5%82awomirSurowiec"},"attachments":[{"id":43538921,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/43538921/thumbnails/1.jpg","file_name":"Half_of_coronary_patients_are_not_instru20160309-24861-16rucda.pdf","download_url":"https://www.academia.edu/attachments/43538921/download_file","bulk_download_file_name":"Half_of_coronary_patients_are_not_instru.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/43538921/Half_of_coronary_patients_are_not_instru20160309-24861-16rucda-libre.pdf?1457521559=\u0026response-content-disposition=attachment%3B+filename%3DHalf_of_coronary_patients_are_not_instru.pdf\u0026Expires=1743675856\u0026Signature=Ocvc8vY4rdNRUFHjNWJZlMjH3ynN~J1jEfsIZFGpde7spXV0Sr6Q4PCl-t8utTEULS5TsW3j7krZWmRl5NbyEMNTWLHP67EpfK7rNnEJrMsFFCbyThFT747f7MRqQY0Mp2tEsici0vJ5hoTZqun44qc-bHchqJqsZ-v9mj16XNSLfuzwxod0anN7u5Z-FC6CWn93K5K9f3W~enfa0qEoaDtoPYoLMe2IT80gpBqcMH~AKPZjxdmO19s3Is1LG7flNLMkycgXKXb7ioLsVLO27uAOswgR1Auwg9ETMe~5~nr9~mGQoR02k9Xpv3uL1cOyKbr41RJdQioCyKXoqJZx1g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology"},{"id":1048,"name":"Health Behavior","url":"https://www.academia.edu/Documents/in/Health_Behavior"},{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment"},{"id":27363,"name":"Poland","url":"https://www.academia.edu/Documents/in/Poland"},{"id":96213,"name":"Hospitalization","url":"https://www.academia.edu/Documents/in/Hospitalization"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":300876,"name":"Acute Coronary Syndrome","url":"https://www.academia.edu/Documents/in/Acute_Coronary_Syndrome"},{"id":327850,"name":"Questionnaires","url":"https://www.academia.edu/Documents/in/Questionnaires"},{"id":398808,"name":"Coronary heart disease","url":"https://www.academia.edu/Documents/in/Coronary_heart_disease"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies"},{"id":479871,"name":"Angina pectoris","url":"https://www.academia.edu/Documents/in/Angina_pectoris"},{"id":584601,"name":"Chi Square Distribution","url":"https://www.academia.edu/Documents/in/Chi_Square_Distribution"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1"},{"id":622589,"name":"Risk Assessment","url":"https://www.academia.edu/Documents/in/Risk_Assessment-2"},{"id":1294607,"name":"Logistic Models","url":"https://www.academia.edu/Documents/in/Logistic_Models"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-15140592-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="15068554"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/15068554/Udro%C5%BCnienia_przewlek%C5%82ych_okluzji_t%C4%99tnic_wie%C5%84cowych_metod%C4%85_wsteczn%C4%85_pierwsze_polskie_do%C5%9Bwiadczenia"><img alt="Research paper thumbnail of Udrożnienia przewlekłych okluzji tętnic wieńcowych metodą wsteczną: pierwsze polskie doświadczenia" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title">Udrożnienia przewlekłych okluzji tętnic wieńcowych metodą wsteczną: pierwsze polskie doświadczenia</div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/TadeuszKr%C3%B3likowski">Tadeusz Królikowski</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/S%C5%82awomirSurowiec">Sławomir Surowiec</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://jagiellonian.academia.edu/PiotrKusak">Piotr Kusak</a></span></div><div class="wp-workCard_item"><span>Kardiologia Polska</span><span>, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The effectiveness of revascularisation procedures of coronary chronic total occlusion (CTO) has b...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The effectiveness of revascularisation procedures of coronary chronic total occlusion (CTO) has been improved by the introduction of retrograde approach. This study compared the outcomes of CTO revascularisation in a single centre in Krakow, Poland using antegrade and retrograde approach. From January 2011 to September 2013, 150 patients underwent 159 procedures for percutaneous revascularisation of CTO of 153 vessels. Of the 159 procedures, 124 (78%) were performed using an antegrade approach and 35 (22%) using a retrograde approach. All patients were symptomatic, with mean CCS class (2.3 ± 0.6 vs. 2.1 ± 0.7, p = 0.9), mean age (59.2 ± 8.3 vs. 62.6 ± 9.9 years, p = 0.067), and mean number of males (81.3% vs. 81.8%, p = 0.9) similar in the retrograde and antegrade groups, respectively. Most patients in both groups had ejection fraction (EF) ≥ 50% (84.4% vs. 74.4%, respectively). Occlusions assessed according to the J-CTO score showed that 82.9% and 56.4%, respectively, were rated as difficult or very difficult (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). Overall procedural success rate was 88.2%, 87.9% in the antegrade, and 74.3% in the retrograde group. Complication rates were low and similar in two groups. However, the retrograde approach was associated with a longer mean fluoroscopy time (47.8 ± 19.6 vs. 19.3 ± 10.0 min, p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.00001) and higher volume of contrast fluid (494.6 ± 142.4 vs. 291.9 ± 118.1 mL, p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.00001). Using novel equipment with adequate experience allowed high rates of successful revascularisation. The retrograde technique for CTO revascularisation showed good overall success and was safe.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="15068554"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="15068554"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 15068554; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=15068554]").text(description); $(".js-view-count[data-work-id=15068554]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 15068554; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='15068554']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=15068554]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":15068554,"title":"Udrożnienia przewlekłych okluzji tętnic wieńcowych metodą wsteczną: pierwsze polskie doświadczenia","translated_title":"","metadata":{"abstract":"The effectiveness of revascularisation procedures of coronary chronic total occlusion (CTO) has been improved by the introduction of retrograde approach. This study compared the outcomes of CTO revascularisation in a single centre in Krakow, Poland using antegrade and retrograde approach. From January 2011 to September 2013, 150 patients underwent 159 procedures for percutaneous revascularisation of CTO of 153 vessels. Of the 159 procedures, 124 (78%) were performed using an antegrade approach and 35 (22%) using a retrograde approach. All patients were symptomatic, with mean CCS class (2.3 ± 0.6 vs. 2.1 ± 0.7, p = 0.9), mean age (59.2 ± 8.3 vs. 62.6 ± 9.9 years, p = 0.067), and mean number of males (81.3% vs. 81.8%, p = 0.9) similar in the retrograde and antegrade groups, respectively. Most patients in both groups had ejection fraction (EF) ≥ 50% (84.4% vs. 74.4%, respectively). Occlusions assessed according to the J-CTO score showed that 82.9% and 56.4%, respectively, were rated as difficult or very difficult (p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). Overall procedural success rate was 88.2%, 87.9% in the antegrade, and 74.3% in the retrograde group. Complication rates were low and similar in two groups. However, the retrograde approach was associated with a longer mean fluoroscopy time (47.8 ± 19.6 vs. 19.3 ± 10.0 min, p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.00001) and higher volume of contrast fluid (494.6 ± 142.4 vs. 291.9 ± 118.1 mL, p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.00001). Using novel equipment with adequate experience allowed high rates of successful revascularisation. The retrograde technique for CTO revascularisation showed good overall success and was safe.","publication_date":{"day":null,"month":null,"year":2015,"errors":{}},"publication_name":"Kardiologia Polska"},"translated_abstract":"The effectiveness of revascularisation procedures of coronary chronic total occlusion (CTO) has been improved by the introduction of retrograde approach. This study compared the outcomes of CTO revascularisation in a single centre in Krakow, Poland using antegrade and retrograde approach. From January 2011 to September 2013, 150 patients underwent 159 procedures for percutaneous revascularisation of CTO of 153 vessels. Of the 159 procedures, 124 (78%) were performed using an antegrade approach and 35 (22%) using a retrograde approach. All patients were symptomatic, with mean CCS class (2.3 ± 0.6 vs. 2.1 ± 0.7, p = 0.9), mean age (59.2 ± 8.3 vs. 62.6 ± 9.9 years, p = 0.067), and mean number of males (81.3% vs. 81.8%, p = 0.9) similar in the retrograde and antegrade groups, respectively. Most patients in both groups had ejection fraction (EF) ≥ 50% (84.4% vs. 74.4%, respectively). Occlusions assessed according to the J-CTO score showed that 82.9% and 56.4%, respectively, were rated as difficult or very difficult (p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). Overall procedural success rate was 88.2%, 87.9% in the antegrade, and 74.3% in the retrograde group. Complication rates were low and similar in two groups. However, the retrograde approach was associated with a longer mean fluoroscopy time (47.8 ± 19.6 vs. 19.3 ± 10.0 min, p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.00001) and higher volume of contrast fluid (494.6 ± 142.4 vs. 291.9 ± 118.1 mL, p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.00001). Using novel equipment with adequate experience allowed high rates of successful revascularisation. The retrograde technique for CTO revascularisation showed good overall success and was safe.","internal_url":"https://www.academia.edu/15068554/Udro%C5%BCnienia_przewlek%C5%82ych_okluzji_t%C4%99tnic_wie%C5%84cowych_metod%C4%85_wsteczn%C4%85_pierwsze_polskie_do%C5%9Bwiadczenia","translated_internal_url":"","created_at":"2015-08-21T00:42:30.785-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":34098823,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":4879886,"work_id":15068554,"tagging_user_id":34098823,"tagged_user_id":33064983,"co_author_invite_id":null,"email":"l***i@poczta.fm","display_order":0,"name":"Leszek Bryniarski","title":"Udrożnienia przewlekłych okluzji tętnic wieńcowych metodą wsteczną: pierwsze polskie doświadczenia"},{"id":4879890,"work_id":15068554,"tagging_user_id":34098823,"tagged_user_id":33097976,"co_author_invite_id":null,"email":"p***i@interia.pl","affiliation":"Jagiellonian University in Krakow","display_order":4194304,"name":"P. Jankowski","title":"Udrożnienia przewlekłych okluzji tętnic wieńcowych metodą wsteczną: pierwsze polskie doświadczenia"},{"id":4879893,"work_id":15068554,"tagging_user_id":34098823,"tagged_user_id":34036833,"co_author_invite_id":null,"email":"r***7@interia.pl","display_order":6291456,"name":"Marek Rajzer","title":"Udrożnienia przewlekłych okluzji tętnic wieńcowych metodą wsteczną: pierwsze polskie doświadczenia"},{"id":4879900,"work_id":15068554,"tagging_user_id":34098823,"tagged_user_id":34178405,"co_author_invite_id":1108757,"email":"s***c@wp.pl","display_order":7340032,"name":"Sławomir Surowiec","title":"Udrożnienia przewlekłych okluzji tętnic wieńcowych metodą wsteczną: pierwsze polskie doświadczenia"},{"id":4879901,"work_id":15068554,"tagging_user_id":34098823,"tagged_user_id":34259336,"co_author_invite_id":1108758,"email":"k***r@gmail.com","affiliation":"Jagiellonian University","display_order":7864320,"name":"Piotr Kusak","title":"Udrożnienia przewlekłych okluzji tętnic wieńcowych metodą wsteczną: pierwsze polskie doświadczenia"},{"id":4879902,"work_id":15068554,"tagging_user_id":34098823,"tagged_user_id":null,"co_author_invite_id":757268,"email":"m***a@kinga.cyf-kr.edu.pl","display_order":8126464,"name":"Krzysztof Żmudka","title":"Udrożnienia przewlekłych okluzji tętnic wieńcowych metodą wsteczną: pierwsze polskie doświadczenia"},{"id":4879903,"work_id":15068554,"tagging_user_id":34098823,"tagged_user_id":null,"co_author_invite_id":757274,"email":"m***k@cyfr-kr.edu.pl","display_order":8257536,"name":"Dariusz Dudek","title":"Udrożnienia przewlekłych okluzji tętnic wieńcowych metodą wsteczną: pierwsze polskie doświadczenia"}],"downloadable_attachments":[],"slug":"Udrożnienia_przewlekłych_okluzji_tętnic_wieńcowych_metodą_wsteczną_pierwsze_polskie_doświadczenia","translated_slug":"","page_count":null,"language":"en","content_type":"Work","summary":"The effectiveness of revascularisation procedures of coronary chronic total occlusion (CTO) has been improved by the introduction of retrograde approach. This study compared the outcomes of CTO revascularisation in a single centre in Krakow, Poland using antegrade and retrograde approach. From January 2011 to September 2013, 150 patients underwent 159 procedures for percutaneous revascularisation of CTO of 153 vessels. Of the 159 procedures, 124 (78%) were performed using an antegrade approach and 35 (22%) using a retrograde approach. All patients were symptomatic, with mean CCS class (2.3 ± 0.6 vs. 2.1 ± 0.7, p = 0.9), mean age (59.2 ± 8.3 vs. 62.6 ± 9.9 years, p = 0.067), and mean number of males (81.3% vs. 81.8%, p = 0.9) similar in the retrograde and antegrade groups, respectively. Most patients in both groups had ejection fraction (EF) ≥ 50% (84.4% vs. 74.4%, respectively). Occlusions assessed according to the J-CTO score showed that 82.9% and 56.4%, respectively, were rated as difficult or very difficult (p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). Overall procedural success rate was 88.2%, 87.9% in the antegrade, and 74.3% in the retrograde group. Complication rates were low and similar in two groups. However, the retrograde approach was associated with a longer mean fluoroscopy time (47.8 ± 19.6 vs. 19.3 ± 10.0 min, p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.00001) and higher volume of contrast fluid (494.6 ± 142.4 vs. 291.9 ± 118.1 mL, p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.00001). Using novel equipment with adequate experience allowed high rates of successful revascularisation. The retrograde technique for CTO revascularisation showed good overall success and was safe.","owner":{"id":34098823,"first_name":"Tadeusz","middle_initials":null,"last_name":"Królikowski","page_name":"TadeuszKrólikowski","domain_name":"independent","created_at":"2015-08-21T00:41:38.573-07:00","display_name":"Tadeusz Królikowski","url":"https://independent.academia.edu/TadeuszKr%C3%B3likowski"},"attachments":[],"research_interests":[],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-15068554-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="14944118"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/14944118/Polish_Forum_for_Prevention_of_Cardiovascular_Diseases_Guidelines_on_prophylactic_pharmacotherapy"><img alt="Research paper thumbnail of Polish Forum for Prevention of Cardiovascular Diseases Guidelines on prophylactic pharmacotherapy" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title">Polish Forum for Prevention of Cardiovascular Diseases Guidelines on prophylactic pharmacotherapy</div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/WojciechDrygas">Wojciech Drygas</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/AnettaUndas">Anetta Undas</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a></span></div><div class="wp-workCard_item"><span>Kardiologia polska</span><span>, 2011</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">... Podolec P, Kopeć G, Undas A, Pająk A, Godycki-Ćwirko M, Zdrojewski T, Jankowski P, Drygas W, ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">... Podolec P, Kopeć G, Undas A, Pająk A, Godycki-Ćwirko M, Zdrojewski T, Jankowski P, Drygas W, Rynkiewicz A, Piotrowicz R, Czarnecka D, Naruszewicz M, Opala G, Stańczyk J, Kozek E, Windak A, Banasiak W, Guzik T. PMID: 21332073 [PubMed - in process].</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14944118"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14944118"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14944118; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14944118]").text(description); $(".js-view-count[data-work-id=14944118]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14944118; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14944118']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14944118]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14944118,"title":"Polish Forum for Prevention of Cardiovascular Diseases Guidelines on prophylactic pharmacotherapy","translated_title":"","metadata":{"abstract":"... Podolec P, Kopeć G, Undas A, Pająk A, Godycki-Ćwirko M, Zdrojewski T, Jankowski P, Drygas W, Rynkiewicz A, Piotrowicz R, Czarnecka D, Naruszewicz M, Opala G, Stańczyk J, Kozek E, Windak A, Banasiak W, Guzik T. PMID: 21332073 [PubMed - in process].","publication_date":{"day":null,"month":null,"year":2011,"errors":{}},"publication_name":"Kardiologia polska"},"translated_abstract":"... Podolec P, Kopeć G, Undas A, Pająk A, Godycki-Ćwirko M, Zdrojewski T, Jankowski P, Drygas W, Rynkiewicz A, Piotrowicz R, Czarnecka D, Naruszewicz M, Opala G, Stańczyk J, Kozek E, Windak A, Banasiak W, Guzik T. PMID: 21332073 [PubMed - in process].","internal_url":"https://www.academia.edu/14944118/Polish_Forum_for_Prevention_of_Cardiovascular_Diseases_Guidelines_on_prophylactic_pharmacotherapy","translated_internal_url":"","created_at":"2015-08-15T11:18:11.098-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":33935206,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":4676967,"work_id":14944118,"tagging_user_id":33935206,"tagged_user_id":213340266,"co_author_invite_id":1040190,"email":"w***s@ikard.pl","display_order":0,"name":"Wojciech Drygas","title":"Polish Forum for Prevention of Cardiovascular Diseases Guidelines on prophylactic pharmacotherapy"},{"id":4677045,"work_id":14944118,"tagging_user_id":33935206,"tagged_user_id":34020020,"co_author_invite_id":1073339,"email":"p***c@interia.pl","display_order":4194304,"name":"Piotr Podolec","title":"Polish Forum for Prevention of Cardiovascular Diseases Guidelines on prophylactic pharmacotherapy"},{"id":4677075,"work_id":14944118,"tagging_user_id":33935206,"tagged_user_id":null,"co_author_invite_id":775471,"email":"t***k@cm-uj.krakow.pl","display_order":6291456,"name":"T. Guzik","title":"Polish Forum for Prevention of Cardiovascular Diseases Guidelines on prophylactic pharmacotherapy"},{"id":4677082,"work_id":14944118,"tagging_user_id":33935206,"tagged_user_id":null,"co_author_invite_id":808360,"email":"g***c@uj.edu.pl","display_order":7340032,"name":"Grzegorz Kopeć","title":"Polish Forum for Prevention of Cardiovascular Diseases Guidelines on prophylactic pharmacotherapy"},{"id":4677084,"work_id":14944118,"tagging_user_id":33935206,"tagged_user_id":33097976,"co_author_invite_id":null,"email":"p***i@interia.pl","affiliation":"Jagiellonian University in Krakow","display_order":7864320,"name":"P. Jankowski","title":"Polish Forum for Prevention of Cardiovascular Diseases Guidelines on prophylactic pharmacotherapy"}],"downloadable_attachments":[],"slug":"Polish_Forum_for_Prevention_of_Cardiovascular_Diseases_Guidelines_on_prophylactic_pharmacotherapy","translated_slug":"","page_count":null,"language":"pl","content_type":"Work","summary":"... Podolec P, Kopeć G, Undas A, Pająk A, Godycki-Ćwirko M, Zdrojewski T, Jankowski P, Drygas W, Rynkiewicz A, Piotrowicz R, Czarnecka D, Naruszewicz M, Opala G, Stańczyk J, Kozek E, Windak A, Banasiak W, Guzik T. PMID: 21332073 [PubMed - in process].","owner":{"id":33935206,"first_name":"Anetta","middle_initials":null,"last_name":"Undas","page_name":"AnettaUndas","domain_name":"independent","created_at":"2015-08-15T11:17:38.855-07:00","display_name":"Anetta Undas","url":"https://independent.academia.edu/AnettaUndas"},"attachments":[],"research_interests":[{"id":27363,"name":"Poland","url":"https://www.academia.edu/Documents/in/Poland"},{"id":559242,"name":"Cardiovascular Diseases","url":"https://www.academia.edu/Documents/in/Cardiovascular_Diseases"},{"id":1246554,"name":"SECONDARY PREVENTION","url":"https://www.academia.edu/Documents/in/SECONDARY_PREVENTION"},{"id":1786368,"name":"Kardiologia","url":"https://www.academia.edu/Documents/in/Kardiologia"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-14944118-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="15003586"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/15003586/_Percutaneous_coronary_angioplasty_in_acute_myocardial_infarction_in_elderly_patients_"><img alt="Research paper thumbnail of [Percutaneous coronary angioplasty in acute myocardial infarction in elderly patients]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title">[Percutaneous coronary angioplasty in acute myocardial infarction in elderly patients]</div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/JacekDragan">Jacek Dragan</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/TadeuszKr%C3%B3likowski">Tadeusz Królikowski</a></span></div><div class="wp-workCard_item"><span>Kardiologia polska</span><span>, 2004</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Over 1/3 of all patients treated for acute myocardial infarction are elderly (over 70 years of ag...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Over 1/3 of all patients treated for acute myocardial infarction are elderly (over 70 years of age). Blood flow restoration in the infarct-related artery is a fundamental therapeutic strategy, however reperfusion therapy is rarely used in the elderly as compared with younger groups. Mortality and complication rates are much higher in the elderly than in younger patients irrespective of the type of reperfusion therapy. Elderly patients are modestly represented in studies undertaken to analyze the efficacy of various types of reperfusion therapy. For this reason the choice of an optimal therapy in acute myocardial infarction in the elderly remains an open question. In the I Department of Cardiology PCI has been the strategy of choice in the treatment of acute myocardial infarction. This is a retrospective analysis of early and late outcomes of primary coronary angioplasty in elderly patients with myocardial infarction. Between June 2001 and December 2003 four hundred and five (405) co...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="15003586"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="15003586"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 15003586; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=15003586]").text(description); $(".js-view-count[data-work-id=15003586]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 15003586; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='15003586']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=15003586]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":15003586,"title":"[Percutaneous coronary angioplasty in acute myocardial infarction in elderly patients]","translated_title":"","metadata":{"abstract":"Over 1/3 of all patients treated for acute myocardial infarction are elderly (over 70 years of age). Blood flow restoration in the infarct-related artery is a fundamental therapeutic strategy, however reperfusion therapy is rarely used in the elderly as compared with younger groups. Mortality and complication rates are much higher in the elderly than in younger patients irrespective of the type of reperfusion therapy. Elderly patients are modestly represented in studies undertaken to analyze the efficacy of various types of reperfusion therapy. For this reason the choice of an optimal therapy in acute myocardial infarction in the elderly remains an open question. In the I Department of Cardiology PCI has been the strategy of choice in the treatment of acute myocardial infarction. This is a retrospective analysis of early and late outcomes of primary coronary angioplasty in elderly patients with myocardial infarction. Between June 2001 and December 2003 four hundred and five (405) co...","publication_date":{"day":null,"month":null,"year":2004,"errors":{}},"publication_name":"Kardiologia polska"},"translated_abstract":"Over 1/3 of all patients treated for acute myocardial infarction are elderly (over 70 years of age). Blood flow restoration in the infarct-related artery is a fundamental therapeutic strategy, however reperfusion therapy is rarely used in the elderly as compared with younger groups. Mortality and complication rates are much higher in the elderly than in younger patients irrespective of the type of reperfusion therapy. Elderly patients are modestly represented in studies undertaken to analyze the efficacy of various types of reperfusion therapy. For this reason the choice of an optimal therapy in acute myocardial infarction in the elderly remains an open question. In the I Department of Cardiology PCI has been the strategy of choice in the treatment of acute myocardial infarction. This is a retrospective analysis of early and late outcomes of primary coronary angioplasty in elderly patients with myocardial infarction. 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Between June 2001 and December 2003 four hundred and five (405) co...","owner":{"id":34006700,"first_name":"Jacek","middle_initials":null,"last_name":"Dragan","page_name":"JacekDragan","domain_name":"independent","created_at":"2015-08-18T04:16:24.928-07:00","display_name":"Jacek Dragan","url":"https://independent.academia.edu/JacekDragan"},"attachments":[],"research_interests":[{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome"},{"id":147196,"name":"Monoclonal Antibodies","url":"https://www.academia.edu/Documents/in/Monoclonal_Antibodies"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":378016,"name":"Myocardial Infarction","url":"https://www.academia.edu/Documents/in/Myocardial_Infarction"},{"id":424295,"name":"Survival Rate","url":"https://www.academia.edu/Documents/in/Survival_Rate"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies"},{"id":546419,"name":"Age Factors","url":"https://www.academia.edu/Documents/in/Age_Factors"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-15003586-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="15003584"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/15003584/_Acute_myocardial_infarction_complicated_by_cardiogenic_shock_treated_with_angioplasty_of_left_main_stenosis_two_case_reports_"><img alt="Research paper thumbnail of [Acute myocardial infarction complicated by cardiogenic shock treated with angioplasty of left main stenosis - two case reports]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title">[Acute myocardial infarction complicated by cardiogenic shock treated with angioplasty of left main stenosis - two case reports]</div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/JacekDragan">Jacek Dragan</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a></span></div><div class="wp-workCard_item"><span>Kardiologia polska</span><span>, 2002</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Two patients with acute myocardial infarction (MI) complicated by cardiogenic shock are described...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Two patients with acute myocardial infarction (MI) complicated by cardiogenic shock are described. Coronary angiography revealed subtotal left main stenosis. Both patients underwent successful primary coronary angioplasty. 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Jankowski</a></span></div><div class="wp-workCard_item"><span>Journal of Human Hypertension</span><span>, 2002</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Arterial pathology is a major contributor to cardiovascular disease, morbidity and mortality. Wom...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Arterial pathology is a major contributor to cardiovascular disease, morbidity and mortality. Women are at higher risk of cardiovascular disease after menopause. Arterial stiffness determined by pulse wave velocity, increases with age both in men and women, whereas arterial compliance in premenopausal women is greater than in men of similar age. 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Jankowski</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/TadeuszKr%C3%B3likowski">Tadeusz Królikowski</a></span></div><div class="wp-workCard_item"><span>Przegla̧d lekarski</span><span>, 2002</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">In patients following a myocardial infarction, heart rate variability is an important prognostic ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">In patients following a myocardial infarction, heart rate variability is an important prognostic factor. Decreased heart rate variability is associated with a higher mortality rate. This study evaluated the influence of recanalisation by percutaneous coronary intervention (PCI) in totally occluded coronary arteries on the heart rate variability in patients with myocardial akinesis in the recanalised artery area. The study group included 22 men (average age 52.8 +/- 7.7) after successful PCI recanalization of the totally occluded artery. All patients had akinesis in the recanalised artery area. All patients underwent 24-hour continuous electrocardiographic Holter monitoring with HRV analysis and echocardiographic dobutamine tests both before the PCI and 6 months afterwards. The population was divided into two groups: group A (10 patients) had contractility adjustments in echocardiographic tests that were performed 6 months after the PCI. Group B (12 patients) did not have contractili...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="15003587"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="15003587"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 15003587; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=15003587]").text(description); $(".js-view-count[data-work-id=15003587]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 15003587; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='15003587']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=15003587]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":15003587,"title":"[The influence of percutaneous coronary recanalization of total coronary occlusions on the heart rate variability ]","translated_title":"","metadata":{"abstract":"In patients following a myocardial infarction, heart rate variability is an important prognostic factor. Decreased heart rate variability is associated with a higher mortality rate. This study evaluated the influence of recanalisation by percutaneous coronary intervention (PCI) in totally occluded coronary arteries on the heart rate variability in patients with myocardial akinesis in the recanalised artery area. The study group included 22 men (average age 52.8 +/- 7.7) after successful PCI recanalization of the totally occluded artery. All patients had akinesis in the recanalised artery area. All patients underwent 24-hour continuous electrocardiographic Holter monitoring with HRV analysis and echocardiographic dobutamine tests both before the PCI and 6 months afterwards. The population was divided into two groups: group A (10 patients) had contractility adjustments in echocardiographic tests that were performed 6 months after the PCI. Group B (12 patients) did not have contractili...","publication_date":{"day":null,"month":null,"year":2002,"errors":{}},"publication_name":"Przegla̧d lekarski"},"translated_abstract":"In patients following a myocardial infarction, heart rate variability is an important prognostic factor. Decreased heart rate variability is associated with a higher mortality rate. This study evaluated the influence of recanalisation by percutaneous coronary intervention (PCI) in totally occluded coronary arteries on the heart rate variability in patients with myocardial akinesis in the recanalised artery area. The study group included 22 men (average age 52.8 +/- 7.7) after successful PCI recanalization of the totally occluded artery. All patients had akinesis in the recanalised artery area. All patients underwent 24-hour continuous electrocardiographic Holter monitoring with HRV analysis and echocardiographic dobutamine tests both before the PCI and 6 months afterwards. The population was divided into two groups: group A (10 patients) had contractility adjustments in echocardiographic tests that were performed 6 months after the PCI. Group B (12 patients) did not have contractili...","internal_url":"https://www.academia.edu/15003587/_The_influence_of_percutaneous_coronary_recanalization_of_total_coronary_occlusions_on_the_heart_rate_variability_","translated_internal_url":"","created_at":"2015-08-18T04:18:01.060-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":34006700,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":4777799,"work_id":15003587,"tagging_user_id":34006700,"tagged_user_id":null,"co_author_invite_id":757212,"email":"a***a@poczta.onet.pl","display_order":0,"name":"Artur Klecha","title":"[The influence of percutaneous coronary recanalization of total coronary occlusions on the heart rate variability ]"},{"id":4777804,"work_id":15003587,"tagging_user_id":34006700,"tagged_user_id":33097976,"co_author_invite_id":null,"email":"p***i@interia.pl","affiliation":"Jagiellonian University in Krakow","display_order":4194304,"name":"P. 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Decreased heart rate variability is associated with a higher mortality rate. This study evaluated the influence of recanalisation by percutaneous coronary intervention (PCI) in totally occluded coronary arteries on the heart rate variability in patients with myocardial akinesis in the recanalised artery area. The study group included 22 men (average age 52.8 +/- 7.7) after successful PCI recanalization of the totally occluded artery. All patients had akinesis in the recanalised artery area. All patients underwent 24-hour continuous electrocardiographic Holter monitoring with HRV analysis and echocardiographic dobutamine tests both before the PCI and 6 months afterwards. The population was divided into two groups: group A (10 patients) had contractility adjustments in echocardiographic tests that were performed 6 months after the PCI. Group B (12 patients) did not have contractili...","owner":{"id":34006700,"first_name":"Jacek","middle_initials":null,"last_name":"Dragan","page_name":"JacekDragan","domain_name":"independent","created_at":"2015-08-18T04:16:24.928-07:00","display_name":"Jacek Dragan","url":"https://independent.academia.edu/JacekDragan"},"attachments":[],"research_interests":[{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome"},{"id":131298,"name":"Heart rate","url":"https://www.academia.edu/Documents/in/Heart_rate"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":378016,"name":"Myocardial Infarction","url":"https://www.academia.edu/Documents/in/Myocardial_Infarction"},{"id":398808,"name":"Coronary heart disease","url":"https://www.academia.edu/Documents/in/Coronary_heart_disease"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-15003587-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="14031704"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/14031704/PREDICTIVE_VALUE_OF_CENTRAL_SYSTOLIC_AND_DIASTOLIC_PRESSURE_IN_CORONARY_PATIENTS_RESULTS_FROM_THE_AORTIC_BLOOD_PRESSURE_AND_SURVIVAL_STUDY_3A_04"><img alt="Research paper thumbnail of PREDICTIVE VALUE OF CENTRAL SYSTOLIC AND DIASTOLIC PRESSURE IN CORONARY PATIENTS. RESULTS FROM THE AORTIC BLOOD PRESSURE AND SURVIVAL STUDY: 3A.04" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title">PREDICTIVE VALUE OF CENTRAL SYSTOLIC AND DIASTOLIC PRESSURE IN CORONARY PATIENTS. RESULTS FROM THE AORTIC BLOOD PRESSURE AND SURVIVAL STUDY: 3A.04</div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/JerzyWili%C5%84ski">Jerzy Wiliński</a></span></div><div class="wp-workCard_item"><span>Journal of Hypertension</span><span>, 2010</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">ABSTRACT Background and Aims: Besides its known cardiac effects, cardiotrophin-1 (CT-1), a cytoki...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">ABSTRACT Background and Aims: Besides its known cardiac effects, cardiotrophin-1 (CT-1), a cytokine belonging to the interleukin-6 family, exerts proliferative and secretory effects in vascular smooth muscle cells. We aimed to investigate the functional and morphological vascular changes induced by chronic CT-1 administration in rats and its involvement in the arterial phenotype of CT-1-null mice in vivo. Methods: A) Recombinant rat CT-1 (20 μg/Kg, IP) was administrated to Wistar rats for six weeks (n = 10/group). Blood pressure (BP) and heart rate were recorded by telemetry. Cardiac function was assessed using PET-scan. B) 2 year-old wild-type (WT) (n = 8) and CT-1-null mice (n = 3) were studied. Vascular structure and function were evaluated by an echo-tracking device. Circumferential wall stress, incremental elastic modulus (Einc), media cross-sectional area and pulse wave velocity (PWV) were measured. Aortic wall collagen and elastin contents were determined using immunohistochemistry, and the expression of collagen type I and III, elastin and fibronectin was quantified by RT-PCR and Western blot in aortic extracts. Results: A) Neither vehicle nor CT-1 treatment modified BP. CT-1-treated rats displayed decreased cardiac output (p &amp;lt; 0.01) as well as wall stress (p &amp;lt; 0.01), Einc (p &amp;lt; 0.01) and PWV (p &amp;lt; 0.05) as compared with vehicle group. CT-1-treated rats also showed increased media cross sectional area (p &amp;lt; 0.01) and collagen content (p &amp;lt; 0.01). CT-1-overloaded rats displayed increased expression of collagen type I (p &amp;lt; 0.05) and III (p &amp;lt; 0.01) and fibronectin (p &amp;lt; 0.01). B) CT-1-null mice presented an increased wall stress (p &amp;lt; 0.05) and Einc (p &amp;lt; 0.05) as compared with WT mice. Media cross sectional area and collagen content were reduced (p &amp;lt; 0.05) in mice lacking CT-1. Conclusions: Normotensive rats subjected to CT-1 overloading developed impaired cardiac and vascular functions, characterized by an increment in arterial stiffness accompanied by an augmented media thickness and extracellular matrix production. Accordingly, CT-1-null mice presented a reduced arterial stiffness and a reduced media thickness and collagen content. Our data show that CT-1 is a key player in arterial thickness and stiffness and in the cardiovascular coupling.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14031704"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14031704"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14031704; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14031704]").text(description); $(".js-view-count[data-work-id=14031704]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14031704; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14031704']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14031704]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14031704,"title":"PREDICTIVE VALUE OF CENTRAL SYSTOLIC AND DIASTOLIC PRESSURE IN CORONARY PATIENTS. RESULTS FROM THE AORTIC BLOOD PRESSURE AND SURVIVAL STUDY: 3A.04","translated_title":"","metadata":{"abstract":"ABSTRACT Background and Aims: Besides its known cardiac effects, cardiotrophin-1 (CT-1), a cytokine belonging to the interleukin-6 family, exerts proliferative and secretory effects in vascular smooth muscle cells. We aimed to investigate the functional and morphological vascular changes induced by chronic CT-1 administration in rats and its involvement in the arterial phenotype of CT-1-null mice in vivo. Methods: A) Recombinant rat CT-1 (20 μg/Kg, IP) was administrated to Wistar rats for six weeks (n = 10/group). Blood pressure (BP) and heart rate were recorded by telemetry. Cardiac function was assessed using PET-scan. B) 2 year-old wild-type (WT) (n = 8) and CT-1-null mice (n = 3) were studied. Vascular structure and function were evaluated by an echo-tracking device. Circumferential wall stress, incremental elastic modulus (Einc), media cross-sectional area and pulse wave velocity (PWV) were measured. Aortic wall collagen and elastin contents were determined using immunohistochemistry, and the expression of collagen type I and III, elastin and fibronectin was quantified by RT-PCR and Western blot in aortic extracts. Results: A) Neither vehicle nor CT-1 treatment modified BP. CT-1-treated rats displayed decreased cardiac output (p \u0026amp;lt; 0.01) as well as wall stress (p \u0026amp;lt; 0.01), Einc (p \u0026amp;lt; 0.01) and PWV (p \u0026amp;lt; 0.05) as compared with vehicle group. CT-1-treated rats also showed increased media cross sectional area (p \u0026amp;lt; 0.01) and collagen content (p \u0026amp;lt; 0.01). CT-1-overloaded rats displayed increased expression of collagen type I (p \u0026amp;lt; 0.05) and III (p \u0026amp;lt; 0.01) and fibronectin (p \u0026amp;lt; 0.01). B) CT-1-null mice presented an increased wall stress (p \u0026amp;lt; 0.05) and Einc (p \u0026amp;lt; 0.05) as compared with WT mice. Media cross sectional area and collagen content were reduced (p \u0026amp;lt; 0.05) in mice lacking CT-1. Conclusions: Normotensive rats subjected to CT-1 overloading developed impaired cardiac and vascular functions, characterized by an increment in arterial stiffness accompanied by an augmented media thickness and extracellular matrix production. Accordingly, CT-1-null mice presented a reduced arterial stiffness and a reduced media thickness and collagen content. Our data show that CT-1 is a key player in arterial thickness and stiffness and in the cardiovascular coupling.","publication_date":{"day":null,"month":null,"year":2010,"errors":{}},"publication_name":"Journal of Hypertension"},"translated_abstract":"ABSTRACT Background and Aims: Besides its known cardiac effects, cardiotrophin-1 (CT-1), a cytokine belonging to the interleukin-6 family, exerts proliferative and secretory effects in vascular smooth muscle cells. We aimed to investigate the functional and morphological vascular changes induced by chronic CT-1 administration in rats and its involvement in the arterial phenotype of CT-1-null mice in vivo. Methods: A) Recombinant rat CT-1 (20 μg/Kg, IP) was administrated to Wistar rats for six weeks (n = 10/group). Blood pressure (BP) and heart rate were recorded by telemetry. Cardiac function was assessed using PET-scan. B) 2 year-old wild-type (WT) (n = 8) and CT-1-null mice (n = 3) were studied. Vascular structure and function were evaluated by an echo-tracking device. Circumferential wall stress, incremental elastic modulus (Einc), media cross-sectional area and pulse wave velocity (PWV) were measured. Aortic wall collagen and elastin contents were determined using immunohistochemistry, and the expression of collagen type I and III, elastin and fibronectin was quantified by RT-PCR and Western blot in aortic extracts. Results: A) Neither vehicle nor CT-1 treatment modified BP. CT-1-treated rats displayed decreased cardiac output (p \u0026amp;lt; 0.01) as well as wall stress (p \u0026amp;lt; 0.01), Einc (p \u0026amp;lt; 0.01) and PWV (p \u0026amp;lt; 0.05) as compared with vehicle group. CT-1-treated rats also showed increased media cross sectional area (p \u0026amp;lt; 0.01) and collagen content (p \u0026amp;lt; 0.01). CT-1-overloaded rats displayed increased expression of collagen type I (p \u0026amp;lt; 0.05) and III (p \u0026amp;lt; 0.01) and fibronectin (p \u0026amp;lt; 0.01). B) CT-1-null mice presented an increased wall stress (p \u0026amp;lt; 0.05) and Einc (p \u0026amp;lt; 0.05) as compared with WT mice. Media cross sectional area and collagen content were reduced (p \u0026amp;lt; 0.05) in mice lacking CT-1. Conclusions: Normotensive rats subjected to CT-1 overloading developed impaired cardiac and vascular functions, characterized by an increment in arterial stiffness accompanied by an augmented media thickness and extracellular matrix production. Accordingly, CT-1-null mice presented a reduced arterial stiffness and a reduced media thickness and collagen content. Our data show that CT-1 is a key player in arterial thickness and stiffness and in the cardiovascular coupling.","internal_url":"https://www.academia.edu/14031704/PREDICTIVE_VALUE_OF_CENTRAL_SYSTOLIC_AND_DIASTOLIC_PRESSURE_IN_CORONARY_PATIENTS_RESULTS_FROM_THE_AORTIC_BLOOD_PRESSURE_AND_SURVIVAL_STUDY_3A_04","translated_internal_url":"","created_at":"2015-07-14T06:56:26.742-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":33059564,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3118053,"work_id":14031704,"tagging_user_id":33059564,"tagged_user_id":33097976,"co_author_invite_id":787306,"email":"p***i@interia.pl","affiliation":"Jagiellonian University in Krakow","display_order":0,"name":"P. Jankowski","title":"PREDICTIVE VALUE OF CENTRAL SYSTOLIC AND DIASTOLIC PRESSURE IN CORONARY PATIENTS. RESULTS FROM THE AORTIC BLOOD PRESSURE AND SURVIVAL STUDY: 3A.04"},{"id":3118057,"work_id":14031704,"tagging_user_id":33059564,"tagged_user_id":null,"co_author_invite_id":787307,"email":"m***k@cyf-kr.edu.pl","display_order":4194304,"name":"K. Kawecka-jaszcz","title":"PREDICTIVE VALUE OF CENTRAL SYSTOLIC AND DIASTOLIC PRESSURE IN CORONARY PATIENTS. RESULTS FROM THE AORTIC BLOOD PRESSURE AND SURVIVAL STUDY: 3A.04"}],"downloadable_attachments":[],"slug":"PREDICTIVE_VALUE_OF_CENTRAL_SYSTOLIC_AND_DIASTOLIC_PRESSURE_IN_CORONARY_PATIENTS_RESULTS_FROM_THE_AORTIC_BLOOD_PRESSURE_AND_SURVIVAL_STUDY_3A_04","translated_slug":"","page_count":null,"language":"en","content_type":"Work","summary":"ABSTRACT Background and Aims: Besides its known cardiac effects, cardiotrophin-1 (CT-1), a cytokine belonging to the interleukin-6 family, exerts proliferative and secretory effects in vascular smooth muscle cells. We aimed to investigate the functional and morphological vascular changes induced by chronic CT-1 administration in rats and its involvement in the arterial phenotype of CT-1-null mice in vivo. Methods: A) Recombinant rat CT-1 (20 μg/Kg, IP) was administrated to Wistar rats for six weeks (n = 10/group). Blood pressure (BP) and heart rate were recorded by telemetry. Cardiac function was assessed using PET-scan. B) 2 year-old wild-type (WT) (n = 8) and CT-1-null mice (n = 3) were studied. Vascular structure and function were evaluated by an echo-tracking device. Circumferential wall stress, incremental elastic modulus (Einc), media cross-sectional area and pulse wave velocity (PWV) were measured. Aortic wall collagen and elastin contents were determined using immunohistochemistry, and the expression of collagen type I and III, elastin and fibronectin was quantified by RT-PCR and Western blot in aortic extracts. Results: A) Neither vehicle nor CT-1 treatment modified BP. CT-1-treated rats displayed decreased cardiac output (p \u0026amp;lt; 0.01) as well as wall stress (p \u0026amp;lt; 0.01), Einc (p \u0026amp;lt; 0.01) and PWV (p \u0026amp;lt; 0.05) as compared with vehicle group. CT-1-treated rats also showed increased media cross sectional area (p \u0026amp;lt; 0.01) and collagen content (p \u0026amp;lt; 0.01). CT-1-overloaded rats displayed increased expression of collagen type I (p \u0026amp;lt; 0.05) and III (p \u0026amp;lt; 0.01) and fibronectin (p \u0026amp;lt; 0.01). B) CT-1-null mice presented an increased wall stress (p \u0026amp;lt; 0.05) and Einc (p \u0026amp;lt; 0.05) as compared with WT mice. Media cross sectional area and collagen content were reduced (p \u0026amp;lt; 0.05) in mice lacking CT-1. Conclusions: Normotensive rats subjected to CT-1 overloading developed impaired cardiac and vascular functions, characterized by an increment in arterial stiffness accompanied by an augmented media thickness and extracellular matrix production. Accordingly, CT-1-null mice presented a reduced arterial stiffness and a reduced media thickness and collagen content. Our data show that CT-1 is a key player in arterial thickness and stiffness and in the cardiovascular coupling.","owner":{"id":33059564,"first_name":"Jerzy","middle_initials":null,"last_name":"Wiliński","page_name":"JerzyWiliński","domain_name":"independent","created_at":"2015-07-14T06:56:00.224-07:00","display_name":"Jerzy Wiliński","url":"https://independent.academia.edu/JerzyWili%C5%84ski"},"attachments":[],"research_interests":[{"id":71399,"name":"Hypertension","url":"https://www.academia.edu/Documents/in/Hypertension"},{"id":88321,"name":"Blood Pressure","url":"https://www.academia.edu/Documents/in/Blood_Pressure"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-14031704-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="14031702"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14031702/Pulsatile_but_Not_Steady_Component_of_Blood_Pressure_Predicts_Cardiovascular_Events_in_Coronary_Patients"><img alt="Research paper thumbnail of Pulsatile but Not Steady Component of Blood Pressure Predicts Cardiovascular Events in Coronary Patients" class="work-thumbnail" src="https://attachments.academia-assets.com/44684977/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14031702/Pulsatile_but_Not_Steady_Component_of_Blood_Pressure_Predicts_Cardiovascular_Events_in_Coronary_Patients">Pulsatile but Not Steady Component of Blood Pressure Predicts Cardiovascular Events in Coronary Patients</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/JerzyWili%C5%84ski">Jerzy Wiliński</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a></span></div><div class="wp-workCard_item"><span>Hypertension</span><span>, 2008</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Although the differences between central and peripheral blood pressure (BP) values have been know...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Although the differences between central and peripheral blood pressure (BP) values have been known for decades, the consequences of decision making based on peripheral rather than central BP have only recently been recognized. There are only a few studies assessing the relationship between intraaortic BP and cardiovascular risk. In addition, the relationship between central BP and the risk of cardiovascular events in a large group of coronary patients has not yet been evaluated. Therefore, the aim of the study was to determine the prognostic significance of central BP-derived indices in patients undergoing coronary angiography. Invasive central BPs were taken at baseline, and study end points were ascertained during over a 4.5-year follow-up in 1109 consecutive patients. The primary end point (cardiovascular death or myocardial infarction or stroke or cardiac arrest or heart transplantation or myocardial revascularization) occurred in 246 (22.2%) patients. Central pulsatility was the most powerful predictor of the primary end point (hazard ratio [HR] 1.30, 95% confidence interval [CI] 1.14 to 1.48). Central pulse pressure was also independently related to the primary end point (HR 1.25, 95% CI 1.09 to 1.43). Central mean BP as well as peripheral BP parameters were not independently related to the primary end point risk. Central pulsatility was also related to risk of cardiovascular death or myocardial infarction or stroke. The pulsatile component of BP is the most important factor related to the cardiovascular risk in coronary patients. It is more closely associated with cardiovascular risk than steady component of BP. (Hypertension. 2008;51:848-855.) Key Words: blood pressure Ⅲ central pulse pressure Ⅲ pulsatility Ⅲ cardiovascular risk Ⅲ atherosclerosis Ⅲ coronary artery disease</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="9a9b86b8fb011aef8962dbcf66a45efe" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44684977,"asset_id":14031702,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44684977/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14031702"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14031702"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14031702; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14031702]").text(description); $(".js-view-count[data-work-id=14031702]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14031702; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14031702']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "9a9b86b8fb011aef8962dbcf66a45efe" } } $('.js-work-strip[data-work-id=14031702]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14031702,"title":"Pulsatile but Not Steady Component of Blood Pressure Predicts Cardiovascular Events in Coronary Patients","translated_title":"","metadata":{"ai_title_tag":"Central Pulsatility Predicts Cardiovascular Events","grobid_abstract":"Although the differences between central and peripheral blood pressure (BP) values have been known for decades, the consequences of decision making based on peripheral rather than central BP have only recently been recognized. There are only a few studies assessing the relationship between intraaortic BP and cardiovascular risk. In addition, the relationship between central BP and the risk of cardiovascular events in a large group of coronary patients has not yet been evaluated. Therefore, the aim of the study was to determine the prognostic significance of central BP-derived indices in patients undergoing coronary angiography. Invasive central BPs were taken at baseline, and study end points were ascertained during over a 4.5-year follow-up in 1109 consecutive patients. The primary end point (cardiovascular death or myocardial infarction or stroke or cardiac arrest or heart transplantation or myocardial revascularization) occurred in 246 (22.2%) patients. Central pulsatility was the most powerful predictor of the primary end point (hazard ratio [HR] 1.30, 95% confidence interval [CI] 1.14 to 1.48). Central pulse pressure was also independently related to the primary end point (HR 1.25, 95% CI 1.09 to 1.43). Central mean BP as well as peripheral BP parameters were not independently related to the primary end point risk. Central pulsatility was also related to risk of cardiovascular death or myocardial infarction or stroke. The pulsatile component of BP is the most important factor related to the cardiovascular risk in coronary patients. It is more closely associated with cardiovascular risk than steady component of BP. (Hypertension. 2008;51:848-855.) Key Words: blood pressure Ⅲ central pulse pressure Ⅲ pulsatility Ⅲ cardiovascular risk Ⅲ atherosclerosis Ⅲ coronary artery disease","publication_date":{"day":null,"month":null,"year":2008,"errors":{}},"publication_name":"Hypertension","grobid_abstract_attachment_id":44684977},"translated_abstract":null,"internal_url":"https://www.academia.edu/14031702/Pulsatile_but_Not_Steady_Component_of_Blood_Pressure_Predicts_Cardiovascular_Events_in_Coronary_Patients","translated_internal_url":"","created_at":"2015-07-14T06:56:26.654-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":33059564,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3118051,"work_id":14031702,"tagging_user_id":33059564,"tagged_user_id":140578231,"co_author_invite_id":330611,"email":"m***k@cyf-kr.edu.pl","display_order":0,"name":"Dariuz Dudek","title":"Pulsatile but Not Steady Component of Blood Pressure Predicts Cardiovascular Events in Coronary Patients"},{"id":3118052,"work_id":14031702,"tagging_user_id":33059564,"tagged_user_id":33097976,"co_author_invite_id":787306,"email":"p***i@interia.pl","affiliation":"Jagiellonian University in Krakow","display_order":4194304,"name":"P. 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There are only a few studies assessing the relationship between intraaortic BP and cardiovascular risk. In addition, the relationship between central BP and the risk of cardiovascular events in a large group of coronary patients has not yet been evaluated. Therefore, the aim of the study was to determine the prognostic significance of central BP-derived indices in patients undergoing coronary angiography. Invasive central BPs were taken at baseline, and study end points were ascertained during over a 4.5-year follow-up in 1109 consecutive patients. The primary end point (cardiovascular death or myocardial infarction or stroke or cardiac arrest or heart transplantation or myocardial revascularization) occurred in 246 (22.2%) patients. Central pulsatility was the most powerful predictor of the primary end point (hazard ratio [HR] 1.30, 95% confidence interval [CI] 1.14 to 1.48). Central pulse pressure was also independently related to the primary end point (HR 1.25, 95% CI 1.09 to 1.43). Central mean BP as well as peripheral BP parameters were not independently related to the primary end point risk. Central pulsatility was also related to risk of cardiovascular death or myocardial infarction or stroke. The pulsatile component of BP is the most important factor related to the cardiovascular risk in coronary patients. It is more closely associated with cardiovascular risk than steady component of BP. (Hypertension. 2008;51:848-855.) Key Words: blood pressure Ⅲ central pulse pressure Ⅲ pulsatility Ⅲ cardiovascular risk Ⅲ atherosclerosis Ⅲ coronary artery disease","owner":{"id":33059564,"first_name":"Jerzy","middle_initials":null,"last_name":"Wiliński","page_name":"JerzyWiliński","domain_name":"independent","created_at":"2015-07-14T06:56:00.224-07:00","display_name":"Jerzy Wiliński","url":"https://independent.academia.edu/JerzyWili%C5%84ski"},"attachments":[{"id":44684977,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/44684977/thumbnails/1.jpg","file_name":"848.pdf","download_url":"https://www.academia.edu/attachments/44684977/download_file","bulk_download_file_name":"Pulsatile_but_Not_Steady_Component_of_Bl.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/44684977/848-libre.pdf?1460530395=\u0026response-content-disposition=attachment%3B+filename%3DPulsatile_but_Not_Steady_Component_of_Bl.pdf\u0026Expires=1743675859\u0026Signature=dXQ5-FQlVi8avbGw5HKiJKe9x5gVWGpB3pLSiWbZ~1MGOuCvNzYGNrE2O6zvcMokKKIJQJqrAIvEuOl3IzN2SAuD0xrYmoKpjZWOcbUn45wdNqdj~ZZ-Ud9R2TcCfCT3IiTh22RckiEtgk7ApNbv6RorJ9iBZqNLl5j1mHRqS2GqcXv8LiOjuVFAqe-uAoiy1Gawx57~HFIGyGLjhknVEScrbkhBRKlY1CvIY7JRBrG4gZV-YM2TByvSsaSDjEUwqVpvsi1zqCenMBGKf0cpMc0Idb3qmdsX7bz9X-rs6-V9bCGwST2QqqGucHcd-9eXZW05OB0EKJJ4G1r0w3CZVg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":1681,"name":"Decision Making","url":"https://www.academia.edu/Documents/in/Decision_Making"},{"id":29154,"name":"Cardiovascular Risk","url":"https://www.academia.edu/Documents/in/Cardiovascular_Risk"},{"id":61235,"name":"Cardiac arrest","url":"https://www.academia.edu/Documents/in/Cardiac_arrest"},{"id":71399,"name":"Hypertension","url":"https://www.academia.edu/Documents/in/Hypertension"},{"id":88321,"name":"Blood Pressure","url":"https://www.academia.edu/Documents/in/Blood_Pressure"},{"id":167876,"name":"Myocardial Revascularization","url":"https://www.academia.edu/Documents/in/Myocardial_Revascularization"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":374984,"name":"Coronary Angiography","url":"https://www.academia.edu/Documents/in/Coronary_Angiography"},{"id":401305,"name":"Betweenness Centrality","url":"https://www.academia.edu/Documents/in/Betweenness_Centrality"},{"id":489727,"name":"Prognosis","url":"https://www.academia.edu/Documents/in/Prognosis"},{"id":497321,"name":"Pulse Pressure","url":"https://www.academia.edu/Documents/in/Pulse_Pressure"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1"},{"id":789977,"name":"Coronary Artery Disease","url":"https://www.academia.edu/Documents/in/Coronary_Artery_Disease"},{"id":987931,"name":"Heart Transplantation","url":"https://www.academia.edu/Documents/in/Heart_Transplantation"},{"id":1035092,"name":"Aorta","url":"https://www.academia.edu/Documents/in/Aorta"},{"id":1272981,"name":"Proportional Hazards Models","url":"https://www.academia.edu/Documents/in/Proportional_Hazards_Models"},{"id":1318932,"name":"Predictive value of tests","url":"https://www.academia.edu/Documents/in/Predictive_value_of_tests"},{"id":1434623,"name":"Pulsatile Flow","url":"https://www.academia.edu/Documents/in/Pulsatile_Flow"},{"id":1587858,"name":"Confidence Interval","url":"https://www.academia.edu/Documents/in/Confidence_Interval"},{"id":2256667,"name":"Brachial artery","url":"https://www.academia.edu/Documents/in/Brachial_artery"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-14031702-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="14087542"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/14087542/AT_HIGH_SALT_INTAKE_CAROTID_INTIMA_MEDIA_THICKNESS_INCREASES_WITH_CENTRAL_PULSE_PRESSURE_A_POPULATION_STUDY_PP_10_400"><img alt="Research paper thumbnail of AT HIGH SALT INTAKE CAROTID INTIMA-MEDIA THICKNESS INCREASES WITH CENTRAL PULSE PRESSURE: A POPULATION STUDY: PP.10.400" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title">AT HIGH SALT INTAKE CAROTID INTIMA-MEDIA THICKNESS INCREASES WITH CENTRAL PULSE PRESSURE: A POPULATION STUDY: PP.10.400</div><div class="wp-workCard_item"><span>Journal of Hypertension</span><span>, 2010</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14087542"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14087542"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14087542; 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Jankowski","url":"https://uj-pl.academia.edu/PJankowski"},"attachments":[],"research_interests":[{"id":71399,"name":"Hypertension","url":"https://www.academia.edu/Documents/in/Hypertension"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":497321,"name":"Pulse Pressure","url":"https://www.academia.edu/Documents/in/Pulse_Pressure"},{"id":634767,"name":"The Carotid Artery Intima Media Thickness","url":"https://www.academia.edu/Documents/in/The_Carotid_Artery_Intima_Media_Thickness"},{"id":718203,"name":"Population Study","url":"https://www.academia.edu/Documents/in/Population_Study"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-14087542-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="14087541"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14087541/Ascending_aortic_blood_pressure_waveform_may_be_related_to_the_risk_of_coronary_artery_disease_in_women_but_not_in_men"><img alt="Research paper thumbnail of Ascending aortic blood pressure waveform may be related to the risk of coronary artery disease in women, but not in men" class="work-thumbnail" src="https://attachments.academia-assets.com/44617930/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14087541/Ascending_aortic_blood_pressure_waveform_may_be_related_to_the_risk_of_coronary_artery_disease_in_women_but_not_in_men">Ascending aortic blood pressure waveform may be related to the risk of coronary artery disease in women, but not in men</a></div><div class="wp-workCard_item"><span>Journal of Human Hypertension</span><span>, 2004</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Recent studies have demonstrated that fractional pulse pressure and fractional diastolic pressure...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Recent studies have demonstrated that fractional pulse pressure and fractional diastolic pressure are related to the risk of coronary artery disease. However, the effect of the ascending aortic pressure waveform on the risk of coronary artery disease in men and women analyzed separately has not been reported. The objective of the study was to assess the relation between ascending aortic blood pressure waveform and the presence of coronary artery disease in men and in women. The study group consisted of 447 patients (302 men and 145 women; mean age: 57.679.8 years) with preserved left ventricular function who were undergoing first diagnostic coronary angiography. After multivariate stepwise adjustments, the odds ratio (OR) and confidence interval (CI) of having coronary artery disease in women was (OR are reported for standard deviation increase in each variable): pulse pressure OR 1.61 (95% CI 1.06-2.46); fractional systolic pressure OR 1.72 (95% CI 1.08-2.71); fractional diastolic pressure OR 0.58 (95% CI 0.37-0.92); fractional pulse pressure OR 1.72 (95% CI 1.08-2.71); and pulsatility index OR 1.74 (95% CI 1.09-2.78). None of the studied variables was independently related to the presence of coronary artery disease in men. In conclusion, fractional systolic and diastolic pressure, pulse pressure, fractional pulse pressure and the ratio of pulse pressure to diastolic pressure may be independently related to the risk of coronary artery disease in women, but not in men.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="32f4a8caf2aba3a3036c217cd5c45287" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44617930,"asset_id":14087541,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44617930/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14087541"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14087541"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14087541; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14087541]").text(description); $(".js-view-count[data-work-id=14087541]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14087541; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14087541']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "32f4a8caf2aba3a3036c217cd5c45287" } } $('.js-work-strip[data-work-id=14087541]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14087541,"title":"Ascending aortic blood pressure waveform may be related to the risk of coronary artery disease in women, but not in men","translated_title":"","metadata":{"grobid_abstract":"Recent studies have demonstrated that fractional pulse pressure and fractional diastolic pressure are related to the risk of coronary artery disease. However, the effect of the ascending aortic pressure waveform on the risk of coronary artery disease in men and women analyzed separately has not been reported. The objective of the study was to assess the relation between ascending aortic blood pressure waveform and the presence of coronary artery disease in men and in women. The study group consisted of 447 patients (302 men and 145 women; mean age: 57.679.8 years) with preserved left ventricular function who were undergoing first diagnostic coronary angiography. After multivariate stepwise adjustments, the odds ratio (OR) and confidence interval (CI) of having coronary artery disease in women was (OR are reported for standard deviation increase in each variable): pulse pressure OR 1.61 (95% CI 1.06-2.46); fractional systolic pressure OR 1.72 (95% CI 1.08-2.71); fractional diastolic pressure OR 0.58 (95% CI 0.37-0.92); fractional pulse pressure OR 1.72 (95% CI 1.08-2.71); and pulsatility index OR 1.74 (95% CI 1.09-2.78). None of the studied variables was independently related to the presence of coronary artery disease in men. 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However, the effect of the ascending aortic pressure waveform on the risk of coronary artery disease in men and women analyzed separately has not been reported. The objective of the study was to assess the relation between ascending aortic blood pressure waveform and the presence of coronary artery disease in men and in women. The study group consisted of 447 patients (302 men and 145 women; mean age: 57.679.8 years) with preserved left ventricular function who were undergoing first diagnostic coronary angiography. After multivariate stepwise adjustments, the odds ratio (OR) and confidence interval (CI) of having coronary artery disease in women was (OR are reported for standard deviation increase in each variable): pulse pressure OR 1.61 (95% CI 1.06-2.46); fractional systolic pressure OR 1.72 (95% CI 1.08-2.71); fractional diastolic pressure OR 0.58 (95% CI 0.37-0.92); fractional pulse pressure OR 1.72 (95% CI 1.08-2.71); and pulsatility index OR 1.74 (95% CI 1.09-2.78). None of the studied variables was independently related to the presence of coronary artery disease in men. In conclusion, fractional systolic and diastolic pressure, pulse pressure, fractional pulse pressure and the ratio of pulse pressure to diastolic pressure may be independently related to the risk of coronary artery disease in women, but not in men.","owner":{"id":33097976,"first_name":"P.","middle_initials":null,"last_name":"Jankowski","page_name":"PJankowski","domain_name":"uj-pl","created_at":"2015-07-15T14:10:55.720-07:00","display_name":"P. 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Jankowski</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/JacekDragan">Jacek Dragan</a></span></div><div class="wp-workCard_item"><span>American journal of …</span><span>, 2004</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Ascending aortic fractional pulse pressure and fractional systolic pressure (FSP) were demonstrat...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Ascending aortic fractional pulse pressure and fractional systolic pressure (FSP) were demonstrated to differentiate patients with and without coronary artery disease. However, no study so far has analyzed the relationship between FSP and fractional diastolic pressure (FDP) and the ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="a2e0f9a033767bf2eebf1edfd3fce142" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44617919,"asset_id":14087540,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44617919/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14087540"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14087540"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14087540; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14087540]").text(description); $(".js-view-count[data-work-id=14087540]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14087540; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14087540']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "a2e0f9a033767bf2eebf1edfd3fce142" } } $('.js-work-strip[data-work-id=14087540]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14087540,"title":"Fractional diastolic and systolic pressure in the ascending aorta are related to the extent of coronary artery disease","translated_title":"","metadata":{"abstract":"Ascending aortic fractional pulse pressure and fractional systolic pressure (FSP) were demonstrated to differentiate patients with and without coronary artery disease. 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Do the potential benefits of pulmonary artery angiography support the decision to perform the procedure?" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title">Acute pulmonary embolism mimicking STEMI. Do the potential benefits of pulmonary artery angiography support the decision to perform the procedure?</div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/JerzyWili%C5%84ski">Jerzy Wiliński</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/MarekRajzer">Marek Rajzer</a></span></div><div class="wp-workCard_item"><span>Przegla̧d lekarski</span><span>, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">This case report concerns a 68 year old male with, type 2 diabetes, stage 3 hypertension, hyperch...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">This case report concerns a 68 year old male with, type 2 diabetes, stage 3 hypertension, hypercholesterolemia, myocardial infarction (MI) 20 years ago. He was admitted to the catheterization laboratory with suspected acute inferior wall MI. Angiography of pulmonary arteries revealed massive thrombosis.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14031709"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14031709"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14031709; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14031709]").text(description); $(".js-view-count[data-work-id=14031709]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14031709; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14031709']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14031709]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14031709,"title":"Acute pulmonary embolism mimicking STEMI. 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Angiography of pulmonary arteries revealed massive thrombosis.","internal_url":"https://www.academia.edu/14031709/Acute_pulmonary_embolism_mimicking_STEMI_Do_the_potential_benefits_of_pulmonary_artery_angiography_support_the_decision_to_perform_the_procedure","translated_internal_url":"","created_at":"2015-07-14T06:56:27.029-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":33059564,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3118054,"work_id":14031709,"tagging_user_id":33059564,"tagged_user_id":33097976,"co_author_invite_id":787306,"email":"p***i@interia.pl","affiliation":"Jagiellonian University in Krakow","display_order":0,"name":"P. Jankowski","title":"Acute pulmonary embolism mimicking STEMI. Do the potential benefits of pulmonary artery angiography support the decision to perform the procedure?"},{"id":3118059,"work_id":14031709,"tagging_user_id":33059564,"tagged_user_id":34036833,"co_author_invite_id":787309,"email":"r***7@interia.pl","display_order":4194304,"name":"Marek Rajzer","title":"Acute pulmonary embolism mimicking STEMI. Do the potential benefits of pulmonary artery angiography support the decision to perform the procedure?"}],"downloadable_attachments":[],"slug":"Acute_pulmonary_embolism_mimicking_STEMI_Do_the_potential_benefits_of_pulmonary_artery_angiography_support_the_decision_to_perform_the_procedure","translated_slug":"","page_count":null,"language":"en","content_type":"Work","summary":"This case report concerns a 68 year old male with, type 2 diabetes, stage 3 hypertension, hypercholesterolemia, myocardial infarction (MI) 20 years ago. He was admitted to the catheterization laboratory with suspected acute inferior wall MI. Angiography of pulmonary arteries revealed massive thrombosis.","owner":{"id":33059564,"first_name":"Jerzy","middle_initials":null,"last_name":"Wiliński","page_name":"JerzyWiliński","domain_name":"independent","created_at":"2015-07-14T06:56:00.224-07:00","display_name":"Jerzy Wiliński","url":"https://independent.academia.edu/JerzyWili%C5%84ski"},"attachments":[],"research_interests":[{"id":71399,"name":"Hypertension","url":"https://www.academia.edu/Documents/in/Hypertension"},{"id":102587,"name":"Pulmonary Embolism","url":"https://www.academia.edu/Documents/in/Pulmonary_Embolism"},{"id":130343,"name":"Hypercholesterolemia","url":"https://www.academia.edu/Documents/in/Hypercholesterolemia"},{"id":162159,"name":"Differential Diagnosis","url":"https://www.academia.edu/Documents/in/Differential_Diagnosis"},{"id":247701,"name":"Angiography","url":"https://www.academia.edu/Documents/in/Angiography"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":378016,"name":"Myocardial Infarction","url":"https://www.academia.edu/Documents/in/Myocardial_Infarction"},{"id":915951,"name":"Type 2 Diabetes Mellitus","url":"https://www.academia.edu/Documents/in/Type_2_Diabetes_Mellitus"},{"id":2369445,"name":"Pulmonary Artery","url":"https://www.academia.edu/Documents/in/Pulmonary_Artery"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-14031709-figures'); } }); </script> </div><div class="profile--tab_content_container js-tab-pane tab-pane" data-section-id="3227750" id="papers"><div class="js-work-strip profile--work_container" data-work-id="30659581"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/30659581/Wytyczne_PTL_KLRwP_PTK_post%C4%99powania_w_zaburzeniach_lipidowych_dla_lekarzy_rodzinnych_2016"><img alt="Research paper thumbnail of Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016" class="work-thumbnail" src="https://attachments.academia-assets.com/51102606/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/30659581/Wytyczne_PTL_KLRwP_PTK_post%C4%99powania_w_zaburzeniach_lipidowych_dla_lekarzy_rodzinnych_2016">Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://umed.academia.edu/MaciejBanach">Maciej Banach</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/BarbaraCybulska">Barbara Cybulska</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/MarlenaBroncel">Marlena Broncel</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Przez lata zaburzenia lipidowe w Polsce i na świecie nie były traktowane z należytą uwagą, a w wi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Przez lata zaburzenia lipidowe w Polsce i na świecie nie były traktowane z należytą uwagą, a w wielu przypadkach ich występowania najczęściej zalecana była dieta i zmiana stylu życia. Pomimo wielu działań edukacyjnych towarzystw medycznych w Polsce, w tym także „sygnatariuszy” niniejszych wytycznych, wiedza pacjentów na temat tego niezależnego czynnika ryzyka jest także wciąż bardzo ograniczona. W efekcie tego w Polsce mamy prawie 20 milionów osób z hipercholesterolemią. Nie istnieją kliniki zaburzeń lipidowych, a funkcjonujące poradnie najczęściej nie są dedykowane temu problemowi, ale zaburzeniom metabolicznym i/lub chorobom endokrynologicznym, a sami pacjenci nierzadko leczeni są po prostu w poradniach kardiologicznych. Wynika to także z ograniczeń systemowych, które wcale nie ułatwiają stworzenia sieci poradni lipidowych, pomimo istnienia grupy prawie 70 lekarzy lipidologów certyfikowanych przez Polskie Towarzystwo Lipidologiczne. To<br />właśnie dlatego przez lata w Polsce problem hipercholesterolemii rodzinnej (familial hypercholesterolemia– FH) nie był rozpoznawany<br />jako istotny i mało kto potrafił skojarzyć stężenia cholesterolu LDL (low density lipoprotein) >190 mg/dl (4,9 mmol/l) czy cholesterolu całkowitego 290 mg/dl (7,5 mmol/l) i więcej jako takie, których przyczyną może być choroba uwarunkowana genetycznie, i idąc dalej<br />– zakwalifikować takich pacjentów do grupy dużego i bardzo dużego ryzyka sercowo‑naczyniowego.To właśnie dlatego w Polsce leczenie<br />aferezą pacjentów z najpoważniejszymi zaburzeniami lipidowymi praktycznie nie istnieje (tylko 3 ośrodki). Tymczasem za naszą<br />zachodnią (Niemcy) czy południową (Czechy) granicą rejestr hipercholesterolemii rodzinnej tworzony jest od wielu lat, a w Niemczech liczba ośrodków wykonujących aferezy jest największa w Europie. Już kilkanaście lat temu zwrócono uwagę, że w ocenie ryzyka odległego (20‑letniego) lub tzw. lifetime risk zaburzenia lipidowe są niezależnym czynnikiem ryzyka wystąpienia incydentów sercowo‑naczyniowych, stąd ich optymalne i skuteczne leczenie jest równie ważne, jak terapia cukrzycy czy nadciśnienia tętniczego. Co więcej, nawet w przypadku<br />podjęcia leczenia dyslipidemii stoją przed nami wyzwania pod postacią niestosowania / nieprzepisywania odpowiednich dawek statyn w odniesieniu do ryzyka sercowo‑naczyniowego (co może dotyczyć nawet 80% leczonych pacjentów) czy też dyskontynuacji leczenia, braku skutecznego leczenia skojarzonego mającego na celu redukcję ryzyka rezydualnego czy też właściwego postępowania w przypadku wystąpienia działań niepożądanych związanych z leczeniem. Dlatego właśnie Polskie Towarzystwo Lipidologiczne (PTL) wraz z Kolegium Lekarzy Rodzinnych w Polsce (KLRwP) oraz Polskim Towarzystwem<br />Kardiologicznym (PTK) wspólnie zdecydowały o konieczności przygotowania pierwszych wytycznych dotyczących postępowania<br />w zaburzeniach lipidowych, dedykowanych lekarzom rodzinnym, bo to właśnie oni najczęściej po raz pierwszy diagnozują zaburzenia<br />lipidowe i to na nich w dużej mierze spoczywa odpowiedzialność za pierwsze decyzje terapeutyczne oraz kontynuację leczenia hipolipemizującego.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="72ea64663ff2a15abe84c7de1ad0ecf7" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":51102606,"asset_id":30659581,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/51102606/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="30659581"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="30659581"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 30659581; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=30659581]").text(description); $(".js-view-count[data-work-id=30659581]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 30659581; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='30659581']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "72ea64663ff2a15abe84c7de1ad0ecf7" } } $('.js-work-strip[data-work-id=30659581]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":30659581,"title":"Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016","translated_title":"","metadata":{"abstract":"Przez lata zaburzenia lipidowe w Polsce i na świecie nie były traktowane z należytą uwagą, a w wielu przypadkach ich występowania najczęściej zalecana była dieta i zmiana stylu życia. Pomimo wielu działań edukacyjnych towarzystw medycznych w Polsce, w tym także „sygnatariuszy” niniejszych wytycznych, wiedza pacjentów na temat tego niezależnego czynnika ryzyka jest także wciąż bardzo ograniczona. W efekcie tego w Polsce mamy prawie 20 milionów osób z hipercholesterolemią. Nie istnieją kliniki zaburzeń lipidowych, a funkcjonujące poradnie najczęściej nie są dedykowane temu problemowi, ale zaburzeniom metabolicznym i/lub chorobom endokrynologicznym, a sami pacjenci nierzadko leczeni są po prostu w poradniach kardiologicznych. Wynika to także z ograniczeń systemowych, które wcale nie ułatwiają stworzenia sieci poradni lipidowych, pomimo istnienia grupy prawie 70 lekarzy lipidologów certyfikowanych przez Polskie Towarzystwo Lipidologiczne. To\nwłaśnie dlatego przez lata w Polsce problem hipercholesterolemii rodzinnej (familial hypercholesterolemia– FH) nie był rozpoznawany\njako istotny i mało kto potrafił skojarzyć stężenia cholesterolu LDL (low density lipoprotein) \u003e190 mg/dl (4,9 mmol/l) czy cholesterolu całkowitego 290 mg/dl (7,5 mmol/l) i więcej jako takie, których przyczyną może być choroba uwarunkowana genetycznie, i idąc dalej\n– zakwalifikować takich pacjentów do grupy dużego i bardzo dużego ryzyka sercowo‑naczyniowego.To właśnie dlatego w Polsce leczenie\naferezą pacjentów z najpoważniejszymi zaburzeniami lipidowymi praktycznie nie istnieje (tylko 3 ośrodki). Tymczasem za naszą\nzachodnią (Niemcy) czy południową (Czechy) granicą rejestr hipercholesterolemii rodzinnej tworzony jest od wielu lat, a w Niemczech liczba ośrodków wykonujących aferezy jest największa w Europie. Już kilkanaście lat temu zwrócono uwagę, że w ocenie ryzyka odległego (20‑letniego) lub tzw. lifetime risk zaburzenia lipidowe są niezależnym czynnikiem ryzyka wystąpienia incydentów sercowo‑naczyniowych, stąd ich optymalne i skuteczne leczenie jest równie ważne, jak terapia cukrzycy czy nadciśnienia tętniczego. Co więcej, nawet w przypadku\npodjęcia leczenia dyslipidemii stoją przed nami wyzwania pod postacią niestosowania / nieprzepisywania odpowiednich dawek statyn w odniesieniu do ryzyka sercowo‑naczyniowego (co może dotyczyć nawet 80% leczonych pacjentów) czy też dyskontynuacji leczenia, braku skutecznego leczenia skojarzonego mającego na celu redukcję ryzyka rezydualnego czy też właściwego postępowania w przypadku wystąpienia działań niepożądanych związanych z leczeniem. Dlatego właśnie Polskie Towarzystwo Lipidologiczne (PTL) wraz z Kolegium Lekarzy Rodzinnych w Polsce (KLRwP) oraz Polskim Towarzystwem\nKardiologicznym (PTK) wspólnie zdecydowały o konieczności przygotowania pierwszych wytycznych dotyczących postępowania\nw zaburzeniach lipidowych, dedykowanych lekarzom rodzinnym, bo to właśnie oni najczęściej po raz pierwszy diagnozują zaburzenia\nlipidowe i to na nich w dużej mierze spoczywa odpowiedzialność za pierwsze decyzje terapeutyczne oraz kontynuację leczenia hipolipemizującego."},"translated_abstract":"Przez lata zaburzenia lipidowe w Polsce i na świecie nie były traktowane z należytą uwagą, a w wielu przypadkach ich występowania najczęściej zalecana była dieta i zmiana stylu życia. Pomimo wielu działań edukacyjnych towarzystw medycznych w Polsce, w tym także „sygnatariuszy” niniejszych wytycznych, wiedza pacjentów na temat tego niezależnego czynnika ryzyka jest także wciąż bardzo ograniczona. W efekcie tego w Polsce mamy prawie 20 milionów osób z hipercholesterolemią. Nie istnieją kliniki zaburzeń lipidowych, a funkcjonujące poradnie najczęściej nie są dedykowane temu problemowi, ale zaburzeniom metabolicznym i/lub chorobom endokrynologicznym, a sami pacjenci nierzadko leczeni są po prostu w poradniach kardiologicznych. Wynika to także z ograniczeń systemowych, które wcale nie ułatwiają stworzenia sieci poradni lipidowych, pomimo istnienia grupy prawie 70 lekarzy lipidologów certyfikowanych przez Polskie Towarzystwo Lipidologiczne. To\nwłaśnie dlatego przez lata w Polsce problem hipercholesterolemii rodzinnej (familial hypercholesterolemia– FH) nie był rozpoznawany\njako istotny i mało kto potrafił skojarzyć stężenia cholesterolu LDL (low density lipoprotein) \u003e190 mg/dl (4,9 mmol/l) czy cholesterolu całkowitego 290 mg/dl (7,5 mmol/l) i więcej jako takie, których przyczyną może być choroba uwarunkowana genetycznie, i idąc dalej\n– zakwalifikować takich pacjentów do grupy dużego i bardzo dużego ryzyka sercowo‑naczyniowego.To właśnie dlatego w Polsce leczenie\naferezą pacjentów z najpoważniejszymi zaburzeniami lipidowymi praktycznie nie istnieje (tylko 3 ośrodki). Tymczasem za naszą\nzachodnią (Niemcy) czy południową (Czechy) granicą rejestr hipercholesterolemii rodzinnej tworzony jest od wielu lat, a w Niemczech liczba ośrodków wykonujących aferezy jest największa w Europie. Już kilkanaście lat temu zwrócono uwagę, że w ocenie ryzyka odległego (20‑letniego) lub tzw. lifetime risk zaburzenia lipidowe są niezależnym czynnikiem ryzyka wystąpienia incydentów sercowo‑naczyniowych, stąd ich optymalne i skuteczne leczenie jest równie ważne, jak terapia cukrzycy czy nadciśnienia tętniczego. Co więcej, nawet w przypadku\npodjęcia leczenia dyslipidemii stoją przed nami wyzwania pod postacią niestosowania / nieprzepisywania odpowiednich dawek statyn w odniesieniu do ryzyka sercowo‑naczyniowego (co może dotyczyć nawet 80% leczonych pacjentów) czy też dyskontynuacji leczenia, braku skutecznego leczenia skojarzonego mającego na celu redukcję ryzyka rezydualnego czy też właściwego postępowania w przypadku wystąpienia działań niepożądanych związanych z leczeniem. Dlatego właśnie Polskie Towarzystwo Lipidologiczne (PTL) wraz z Kolegium Lekarzy Rodzinnych w Polsce (KLRwP) oraz Polskim Towarzystwem\nKardiologicznym (PTK) wspólnie zdecydowały o konieczności przygotowania pierwszych wytycznych dotyczących postępowania\nw zaburzeniach lipidowych, dedykowanych lekarzom rodzinnym, bo to właśnie oni najczęściej po raz pierwszy diagnozują zaburzenia\nlipidowe i to na nich w dużej mierze spoczywa odpowiedzialność za pierwsze decyzje terapeutyczne oraz kontynuację leczenia hipolipemizującego.","internal_url":"https://www.academia.edu/30659581/Wytyczne_PTL_KLRwP_PTK_post%C4%99powania_w_zaburzeniach_lipidowych_dla_lekarzy_rodzinnych_2016","translated_internal_url":"","created_at":"2016-12-29T01:39:29.563-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":781527,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":26818349,"work_id":30659581,"tagging_user_id":781527,"tagged_user_id":33097976,"co_author_invite_id":null,"email":"p***i@interia.pl","affiliation":"Jagiellonian University in Krakow","display_order":1,"name":"P. Jankowski","title":"Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016"},{"id":26818350,"work_id":30659581,"tagging_user_id":781527,"tagged_user_id":58427629,"co_author_invite_id":1072776,"email":"j***k@sla.pl","display_order":2,"name":"Jacek Jóźwiak","title":"Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016"},{"id":26818351,"work_id":30659581,"tagging_user_id":781527,"tagged_user_id":36507410,"co_author_invite_id":null,"email":"b***a@wp.pl","display_order":3,"name":"Barbara Cybulska","title":"Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016"},{"id":26818352,"work_id":30659581,"tagging_user_id":781527,"tagged_user_id":null,"co_author_invite_id":414609,"email":"m***k@cyf-kr.edu.pl","display_order":4,"name":"Adam Windak","title":"Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016"},{"id":26818353,"work_id":30659581,"tagging_user_id":781527,"tagged_user_id":3044646,"co_author_invite_id":null,"email":"t***k@yahoo.com","affiliation":"Jagiellonian University","display_order":5,"name":"Tomasz Guzik","title":"Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016"},{"id":26818354,"work_id":30659581,"tagging_user_id":781527,"tagged_user_id":37207463,"co_author_invite_id":null,"email":"a***z@wum.edu.pl","display_order":6,"name":"Artur Mamcarz","title":"Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016"},{"id":26818355,"work_id":30659581,"tagging_user_id":781527,"tagged_user_id":58413595,"co_author_invite_id":5901923,"email":"m***l@umed.lodz.pl","display_order":7,"name":"Marlena Broncel","title":"Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016"},{"id":26818356,"work_id":30659581,"tagging_user_id":781527,"tagged_user_id":58578858,"co_author_invite_id":5901924,"email":"m***i@cyf-kr.edu.pl","display_order":8,"name":"Tomasz Tomasik","title":"Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016"},{"id":26958943,"work_id":30659581,"tagging_user_id":58413595,"tagged_user_id":null,"co_author_invite_id":5927999,"email":"s***a@termedia.pl","display_order":4194308,"name":"Konferencje Termedia","title":"Wytyczne PTL/KLRwP/PTK postępowania w zaburzeniach lipidowych dla lekarzy rodzinnych 2016"}],"downloadable_attachments":[{"id":51102606,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/51102606/thumbnails/1.jpg","file_name":"LPOZ_Art_28951-10.pdf","download_url":"https://www.academia.edu/attachments/51102606/download_file","bulk_download_file_name":"Wytyczne_PTL_KLRwP_PTK_postepowania_w_za.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/51102606/LPOZ_Art_28951-10-libre.pdf?1483004525=\u0026response-content-disposition=attachment%3B+filename%3DWytyczne_PTL_KLRwP_PTK_postepowania_w_za.pdf\u0026Expires=1743642920\u0026Signature=Q-QEQgQ96~JBB29brJ-FybW7mGurtcpIMvFOjiGHrWcBPxtu~YeQqoHwMnVVTgUQ3-X~7VqKtdI60cBPfR9SsX3sTYdryXOdQNeL-YR09AVER91L6CvJAxDv8NttOf6ZHKrjevfD5gJZQdyj~Ikv4hPIOYGL8x9jfESJ-dxVuhJ-6vaOxRUL9Morc0urzDWSy-TQ-ZUHYhej83IBhmMvoqiXZc84Filq-qtzDKt2hm60UjUGZoxDesYgH9s04BsQ1QFCyfuQhyyWIIbhfwoJi~MyTK72oAwUrvOPVK0rgHYrJVPeShAj5TuSDtT-~HQDjSlevv3X-2WWGf9idigD9Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Wytyczne_PTL_KLRwP_PTK_postępowania_w_zaburzeniach_lipidowych_dla_lekarzy_rodzinnych_2016","translated_slug":"","page_count":50,"language":"pl","content_type":"Work","summary":"Przez lata zaburzenia lipidowe w Polsce i na świecie nie były traktowane z należytą uwagą, a w wielu przypadkach ich występowania najczęściej zalecana była dieta i zmiana stylu życia. Pomimo wielu działań edukacyjnych towarzystw medycznych w Polsce, w tym także „sygnatariuszy” niniejszych wytycznych, wiedza pacjentów na temat tego niezależnego czynnika ryzyka jest także wciąż bardzo ograniczona. W efekcie tego w Polsce mamy prawie 20 milionów osób z hipercholesterolemią. Nie istnieją kliniki zaburzeń lipidowych, a funkcjonujące poradnie najczęściej nie są dedykowane temu problemowi, ale zaburzeniom metabolicznym i/lub chorobom endokrynologicznym, a sami pacjenci nierzadko leczeni są po prostu w poradniach kardiologicznych. Wynika to także z ograniczeń systemowych, które wcale nie ułatwiają stworzenia sieci poradni lipidowych, pomimo istnienia grupy prawie 70 lekarzy lipidologów certyfikowanych przez Polskie Towarzystwo Lipidologiczne. To\nwłaśnie dlatego przez lata w Polsce problem hipercholesterolemii rodzinnej (familial hypercholesterolemia– FH) nie był rozpoznawany\njako istotny i mało kto potrafił skojarzyć stężenia cholesterolu LDL (low density lipoprotein) \u003e190 mg/dl (4,9 mmol/l) czy cholesterolu całkowitego 290 mg/dl (7,5 mmol/l) i więcej jako takie, których przyczyną może być choroba uwarunkowana genetycznie, i idąc dalej\n– zakwalifikować takich pacjentów do grupy dużego i bardzo dużego ryzyka sercowo‑naczyniowego.To właśnie dlatego w Polsce leczenie\naferezą pacjentów z najpoważniejszymi zaburzeniami lipidowymi praktycznie nie istnieje (tylko 3 ośrodki). Tymczasem za naszą\nzachodnią (Niemcy) czy południową (Czechy) granicą rejestr hipercholesterolemii rodzinnej tworzony jest od wielu lat, a w Niemczech liczba ośrodków wykonujących aferezy jest największa w Europie. Już kilkanaście lat temu zwrócono uwagę, że w ocenie ryzyka odległego (20‑letniego) lub tzw. lifetime risk zaburzenia lipidowe są niezależnym czynnikiem ryzyka wystąpienia incydentów sercowo‑naczyniowych, stąd ich optymalne i skuteczne leczenie jest równie ważne, jak terapia cukrzycy czy nadciśnienia tętniczego. Co więcej, nawet w przypadku\npodjęcia leczenia dyslipidemii stoją przed nami wyzwania pod postacią niestosowania / nieprzepisywania odpowiednich dawek statyn w odniesieniu do ryzyka sercowo‑naczyniowego (co może dotyczyć nawet 80% leczonych pacjentów) czy też dyskontynuacji leczenia, braku skutecznego leczenia skojarzonego mającego na celu redukcję ryzyka rezydualnego czy też właściwego postępowania w przypadku wystąpienia działań niepożądanych związanych z leczeniem. Dlatego właśnie Polskie Towarzystwo Lipidologiczne (PTL) wraz z Kolegium Lekarzy Rodzinnych w Polsce (KLRwP) oraz Polskim Towarzystwem\nKardiologicznym (PTK) wspólnie zdecydowały o konieczności przygotowania pierwszych wytycznych dotyczących postępowania\nw zaburzeniach lipidowych, dedykowanych lekarzom rodzinnym, bo to właśnie oni najczęściej po raz pierwszy diagnozują zaburzenia\nlipidowe i to na nich w dużej mierze spoczywa odpowiedzialność za pierwsze decyzje terapeutyczne oraz kontynuację leczenia hipolipemizującego.","owner":{"id":781527,"first_name":"Maciej","middle_initials":null,"last_name":"Banach","page_name":"MaciejBanach","domain_name":"umed","created_at":"2011-09-23T06:49:52.933-07:00","display_name":"Maciej Banach","url":"https://umed.academia.edu/MaciejBanach"},"attachments":[{"id":51102606,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/51102606/thumbnails/1.jpg","file_name":"LPOZ_Art_28951-10.pdf","download_url":"https://www.academia.edu/attachments/51102606/download_file","bulk_download_file_name":"Wytyczne_PTL_KLRwP_PTK_postepowania_w_za.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/51102606/LPOZ_Art_28951-10-libre.pdf?1483004525=\u0026response-content-disposition=attachment%3B+filename%3DWytyczne_PTL_KLRwP_PTK_postepowania_w_za.pdf\u0026Expires=1743642920\u0026Signature=Q-QEQgQ96~JBB29brJ-FybW7mGurtcpIMvFOjiGHrWcBPxtu~YeQqoHwMnVVTgUQ3-X~7VqKtdI60cBPfR9SsX3sTYdryXOdQNeL-YR09AVER91L6CvJAxDv8NttOf6ZHKrjevfD5gJZQdyj~Ikv4hPIOYGL8x9jfESJ-dxVuhJ-6vaOxRUL9Morc0urzDWSy-TQ-ZUHYhej83IBhmMvoqiXZc84Filq-qtzDKt2hm60UjUGZoxDesYgH9s04BsQ1QFCyfuQhyyWIIbhfwoJi~MyTK72oAwUrvOPVK0rgHYrJVPeShAj5TuSDtT-~HQDjSlevv3X-2WWGf9idigD9Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":2974,"name":"Primary Health Care","url":"https://www.academia.edu/Documents/in/Primary_Health_Care"},{"id":52055,"name":"Lipids","url":"https://www.academia.edu/Documents/in/Lipids"},{"id":167643,"name":"Statins","url":"https://www.academia.edu/Documents/in/Statins"},{"id":227278,"name":"Atherogenic Dyslipidemia","url":"https://www.academia.edu/Documents/in/Atherogenic_Dyslipidemia"},{"id":235465,"name":"Guidelines","url":"https://www.academia.edu/Documents/in/Guidelines"},{"id":333996,"name":"Recommendations","url":"https://www.academia.edu/Documents/in/Recommendations"},{"id":437953,"name":"Dyslipidemia","url":"https://www.academia.edu/Documents/in/Dyslipidemia"},{"id":1157351,"name":"Primary Health Centre","url":"https://www.academia.edu/Documents/in/Primary_Health_Centre"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-30659581-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="30659717"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/30659717/PoLA_CFPiP_PCS_Guidelines_for_the_Management_of_Dyslipidaemias_for_Family_Physicians_2016"><img alt="Research paper thumbnail of PoLA/CFPiP/PCS Guidelines for the Management of Dyslipidaemias for Family Physicians 2016" class="work-thumbnail" src="https://attachments.academia-assets.com/51102721/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/30659717/PoLA_CFPiP_PCS_Guidelines_for_the_Management_of_Dyslipidaemias_for_Family_Physicians_2016">PoLA/CFPiP/PCS Guidelines for the Management of Dyslipidaemias for Family Physicians 2016</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://umed.academia.edu/MaciejBanach">Maciej Banach</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/JacekJ%C3%B3%C5%BAwiak">Jacek Jóźwiak</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/BarbaraCybulska">Barbara Cybulska</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/MarlenaBroncel">Marlena Broncel</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">For many years, dyslipidaemias failed to receive the attention they deserve, both in Poland and a...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">For many years, dyslipidaemias failed to receive the attention they deserve, both in Poland and across the world. In many cases, the most common recommendation given to patients suffering from lipid disorders was to change their diet and lifestyle. Despite multiple educational efforts undertaken by medical societies in Poland, including the signatories of the Guidelines, the knowledge of patients about this independent risk factor continues to be very limited even today. As a result, there are nearly 20 million hypercholesterolaemic patients in Poland. Furthermore, there are no medical (lipid) clinics specializing in<br />the treatment of lipid disorders, and existing outpatient clinics are not usually dedicated specifically to dyslipidaemias, but metabolic disorders<br />and/or endocrine conditions. Not uncommonly, patients receive treatment in cardiac outpatient clinics. The existing state of affairs stems partly from systemic constraints, which pose a hindrance to the establishment of a network of lipid outpatient clinics – even though a total of 70 lipidologists have already been certified by the Polish Lipid Association (PoLA). This is precisely why the problem of familial hypercholesterolaemia (FH) in Poland was not recognized as significant for many years. Few physicians were able to consider low density lipoprotein cholesterol (LDL-C) concentrations in excess of 190 mg/dl (4.9 mmol/l) or total cholesterol (TC) concentrations of 290 mg/dl (7.5<br />mmol/l) and more as potentially caused by genetically conditioned disease and, taking the matter further, classify patients presenting with such disorders into high and very high cardiovascular risk groups. This is why the treatment of patients with the most severe lipid disorders with apheresis is practically non-existent in Poland, with only three treatment centres available to patients. In contrast, in neighbouring countries (Germany, Czech Republic), nationwide FH registries have been kept for many years. Germany, in addition, has the largest number of medical centres offering apheresis treatment in Europe. It was first noted about a dozen years ago in the estimation of long-term (20-year) risk or lifetime<br />risk that dyslipidaemias represented an independent risk factor for cardiovascular (CV) events. It thus follows that optimal effective treatment of lipid disorders is as important as the therapy of diabetes<br />or arterial hypertension. What is more, even if dyslipidaemia treatment is undertaken, further challenges must be faced such as failure to use/prescribe statins at doses corresponding to the level of CV risk (the situation may affect as much as 80% of all treated patients), discontinuation of therapy, lack of effective combination treatment aimed at reducing residual risk or failure to ensure appropriate management of undesirable treatment-related effects.<br /><br />In view of the situation outlined above, the PoLA, the College of Family Physicians in Poland (CFPiP) and the Polish Cardiac Society (PCS) have<br />jointly identified a need to draft the first guidelines regulating the management of dyslipidaemias and addressed to family physicians, as they are usually the first to diagnose lipid disorders and they are largely responsible for the initial therapeutic decisions and for the continuation of lipid-lowering therapy (LLT).</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="71f5dcda11b436de5a62c6151163042c" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":51102721,"asset_id":30659717,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/51102721/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="30659717"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="30659717"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 30659717; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=30659717]").text(description); $(".js-view-count[data-work-id=30659717]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 30659717; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='30659717']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "71f5dcda11b436de5a62c6151163042c" } } $('.js-work-strip[data-work-id=30659717]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":30659717,"title":"PoLA/CFPiP/PCS Guidelines for the Management of Dyslipidaemias for Family Physicians 2016","translated_title":"","metadata":{"abstract":"For many years, dyslipidaemias failed to receive the attention they deserve, both in Poland and across the world. In many cases, the most common recommendation given to patients suffering from lipid disorders was to change their diet and lifestyle. Despite multiple educational efforts undertaken by medical societies in Poland, including the signatories of the Guidelines, the knowledge of patients about this independent risk factor continues to be very limited even today. As a result, there are nearly 20 million hypercholesterolaemic patients in Poland. Furthermore, there are no medical (lipid) clinics specializing in\nthe treatment of lipid disorders, and existing outpatient clinics are not usually dedicated specifically to dyslipidaemias, but metabolic disorders\nand/or endocrine conditions. Not uncommonly, patients receive treatment in cardiac outpatient clinics. The existing state of affairs stems partly from systemic constraints, which pose a hindrance to the establishment of a network of lipid outpatient clinics – even though a total of 70 lipidologists have already been certified by the Polish Lipid Association (PoLA). This is precisely why the problem of familial hypercholesterolaemia (FH) in Poland was not recognized as significant for many years. Few physicians were able to consider low density lipoprotein cholesterol (LDL-C) concentrations in excess of 190 mg/dl (4.9 mmol/l) or total cholesterol (TC) concentrations of 290 mg/dl (7.5\nmmol/l) and more as potentially caused by genetically conditioned disease and, taking the matter further, classify patients presenting with such disorders into high and very high cardiovascular risk groups. This is why the treatment of patients with the most severe lipid disorders with apheresis is practically non-existent in Poland, with only three treatment centres available to patients. In contrast, in neighbouring countries (Germany, Czech Republic), nationwide FH registries have been kept for many years. Germany, in addition, has the largest number of medical centres offering apheresis treatment in Europe. It was first noted about a dozen years ago in the estimation of long-term (20-year) risk or lifetime\nrisk that dyslipidaemias represented an independent risk factor for cardiovascular (CV) events. It thus follows that optimal effective treatment of lipid disorders is as important as the therapy of diabetes\nor arterial hypertension. What is more, even if dyslipidaemia treatment is undertaken, further challenges must be faced such as failure to use/prescribe statins at doses corresponding to the level of CV risk (the situation may affect as much as 80% of all treated patients), discontinuation of therapy, lack of effective combination treatment aimed at reducing residual risk or failure to ensure appropriate management of undesirable treatment-related effects.\n\nIn view of the situation outlined above, the PoLA, the College of Family Physicians in Poland (CFPiP) and the Polish Cardiac Society (PCS) have\njointly identified a need to draft the first guidelines regulating the management of dyslipidaemias and addressed to family physicians, as they are usually the first to diagnose lipid disorders and they are largely responsible for the initial therapeutic decisions and for the continuation of lipid-lowering therapy (LLT)."},"translated_abstract":"For many years, dyslipidaemias failed to receive the attention they deserve, both in Poland and across the world. In many cases, the most common recommendation given to patients suffering from lipid disorders was to change their diet and lifestyle. Despite multiple educational efforts undertaken by medical societies in Poland, including the signatories of the Guidelines, the knowledge of patients about this independent risk factor continues to be very limited even today. As a result, there are nearly 20 million hypercholesterolaemic patients in Poland. Furthermore, there are no medical (lipid) clinics specializing in\nthe treatment of lipid disorders, and existing outpatient clinics are not usually dedicated specifically to dyslipidaemias, but metabolic disorders\nand/or endocrine conditions. Not uncommonly, patients receive treatment in cardiac outpatient clinics. The existing state of affairs stems partly from systemic constraints, which pose a hindrance to the establishment of a network of lipid outpatient clinics – even though a total of 70 lipidologists have already been certified by the Polish Lipid Association (PoLA). This is precisely why the problem of familial hypercholesterolaemia (FH) in Poland was not recognized as significant for many years. Few physicians were able to consider low density lipoprotein cholesterol (LDL-C) concentrations in excess of 190 mg/dl (4.9 mmol/l) or total cholesterol (TC) concentrations of 290 mg/dl (7.5\nmmol/l) and more as potentially caused by genetically conditioned disease and, taking the matter further, classify patients presenting with such disorders into high and very high cardiovascular risk groups. This is why the treatment of patients with the most severe lipid disorders with apheresis is practically non-existent in Poland, with only three treatment centres available to patients. In contrast, in neighbouring countries (Germany, Czech Republic), nationwide FH registries have been kept for many years. Germany, in addition, has the largest number of medical centres offering apheresis treatment in Europe. It was first noted about a dozen years ago in the estimation of long-term (20-year) risk or lifetime\nrisk that dyslipidaemias represented an independent risk factor for cardiovascular (CV) events. It thus follows that optimal effective treatment of lipid disorders is as important as the therapy of diabetes\nor arterial hypertension. What is more, even if dyslipidaemia treatment is undertaken, further challenges must be faced such as failure to use/prescribe statins at doses corresponding to the level of CV risk (the situation may affect as much as 80% of all treated patients), discontinuation of therapy, lack of effective combination treatment aimed at reducing residual risk or failure to ensure appropriate management of undesirable treatment-related effects.\n\nIn view of the situation outlined above, the PoLA, the College of Family Physicians in Poland (CFPiP) and the Polish Cardiac Society (PCS) have\njointly identified a need to draft the first guidelines regulating the management of dyslipidaemias and addressed to family physicians, as they are usually the first to diagnose lipid disorders and they are largely responsible for the initial therapeutic decisions and for the continuation of lipid-lowering therapy (LLT).","internal_url":"https://www.academia.edu/30659717/PoLA_CFPiP_PCS_Guidelines_for_the_Management_of_Dyslipidaemias_for_Family_Physicians_2016","translated_internal_url":"","created_at":"2016-12-29T01:52:57.799-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":781527,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":26818400,"work_id":30659717,"tagging_user_id":781527,"tagged_user_id":781527,"co_author_invite_id":5901942,"email":"m***h@aol.co.uk","affiliation":"Medical University of Lodz, Lodz, Poland","display_order":1,"name":"Maciej Banach","title":"PoLA/CFPiP/PCS Guidelines for the Management of Dyslipidaemias for Family Physicians 2016"},{"id":26818401,"work_id":30659717,"tagging_user_id":781527,"tagged_user_id":33097976,"co_author_invite_id":null,"email":"p***i@interia.pl","affiliation":"Jagiellonian University in Krakow","display_order":2,"name":"P. 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In many cases, the most common recommendation given to patients suffering from lipid disorders was to change their diet and lifestyle. Despite multiple educational efforts undertaken by medical societies in Poland, including the signatories of the Guidelines, the knowledge of patients about this independent risk factor continues to be very limited even today. As a result, there are nearly 20 million hypercholesterolaemic patients in Poland. Furthermore, there are no medical (lipid) clinics specializing in\nthe treatment of lipid disorders, and existing outpatient clinics are not usually dedicated specifically to dyslipidaemias, but metabolic disorders\nand/or endocrine conditions. Not uncommonly, patients receive treatment in cardiac outpatient clinics. The existing state of affairs stems partly from systemic constraints, which pose a hindrance to the establishment of a network of lipid outpatient clinics – even though a total of 70 lipidologists have already been certified by the Polish Lipid Association (PoLA). This is precisely why the problem of familial hypercholesterolaemia (FH) in Poland was not recognized as significant for many years. Few physicians were able to consider low density lipoprotein cholesterol (LDL-C) concentrations in excess of 190 mg/dl (4.9 mmol/l) or total cholesterol (TC) concentrations of 290 mg/dl (7.5\nmmol/l) and more as potentially caused by genetically conditioned disease and, taking the matter further, classify patients presenting with such disorders into high and very high cardiovascular risk groups. This is why the treatment of patients with the most severe lipid disorders with apheresis is practically non-existent in Poland, with only three treatment centres available to patients. In contrast, in neighbouring countries (Germany, Czech Republic), nationwide FH registries have been kept for many years. Germany, in addition, has the largest number of medical centres offering apheresis treatment in Europe. It was first noted about a dozen years ago in the estimation of long-term (20-year) risk or lifetime\nrisk that dyslipidaemias represented an independent risk factor for cardiovascular (CV) events. It thus follows that optimal effective treatment of lipid disorders is as important as the therapy of diabetes\nor arterial hypertension. What is more, even if dyslipidaemia treatment is undertaken, further challenges must be faced such as failure to use/prescribe statins at doses corresponding to the level of CV risk (the situation may affect as much as 80% of all treated patients), discontinuation of therapy, lack of effective combination treatment aimed at reducing residual risk or failure to ensure appropriate management of undesirable treatment-related effects.\n\nIn view of the situation outlined above, the PoLA, the College of Family Physicians in Poland (CFPiP) and the Polish Cardiac Society (PCS) have\njointly identified a need to draft the first guidelines regulating the management of dyslipidaemias and addressed to family physicians, as they are usually the first to diagnose lipid disorders and they are largely responsible for the initial therapeutic decisions and for the continuation of lipid-lowering therapy (LLT).","owner":{"id":781527,"first_name":"Maciej","middle_initials":null,"last_name":"Banach","page_name":"MaciejBanach","domain_name":"umed","created_at":"2011-09-23T06:49:52.933-07:00","display_name":"Maciej Banach","url":"https://umed.academia.edu/MaciejBanach"},"attachments":[{"id":51102721,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/51102721/thumbnails/1.jpg","file_name":"AOMS_Art_28931-10.pdf","download_url":"https://www.academia.edu/attachments/51102721/download_file","bulk_download_file_name":"PoLA_CFPiP_PCS_Guidelines_for_the_Manage.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/51102721/AOMS_Art_28931-10-libre.pdf?1483005146=\u0026response-content-disposition=attachment%3B+filename%3DPoLA_CFPiP_PCS_Guidelines_for_the_Manage.pdf\u0026Expires=1743615394\u0026Signature=RZNHHF2cDd8QL1LS3eK~CkT7-bmYsuXr1XaPJcSToTmoSfKwGKfrWA2onLMqX8gQBxrmPfyGEkIvmHeWg62s6HuwSH5j~Xczd9-8DU-5ZPn-Goo1J71mDKR5tqSRbXmRlullKruKWo8LJNIu~Rlo0-xQ7qRMPKl92gmrGQwf-WjdfZ634zRCC~lditmQFBIOHm0ntPN5m6FjFE273YB-Uz1w3~18P~rXCiyFawjb997lFcIugIZM6mwcs5sU2VE2CyyLXedJpQ6oGXd9LzJaieZvb1hsiPB7GPDdSYpBmuySQCeC5cColuO-WDT~ni8Jbe9eTeTyF~NM58f5-dQ93Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":231,"name":"Family Therapy","url":"https://www.academia.edu/Documents/in/Family_Therapy"},{"id":2302,"name":"Nutraceuticals","url":"https://www.academia.edu/Documents/in/Nutraceuticals"},{"id":167643,"name":"Statins","url":"https://www.academia.edu/Documents/in/Statins"},{"id":227287,"name":"Athreogenic Dyslipidemia","url":"https://www.academia.edu/Documents/in/Athreogenic_Dyslipidemia"},{"id":235465,"name":"Guidelines","url":"https://www.academia.edu/Documents/in/Guidelines"},{"id":333996,"name":"Recommendations","url":"https://www.academia.edu/Documents/in/Recommendations"},{"id":437953,"name":"Dyslipidemia","url":"https://www.academia.edu/Documents/in/Dyslipidemia"},{"id":957647,"name":"Fibrates","url":"https://www.academia.edu/Documents/in/Fibrates"},{"id":1954133,"name":"PCSK9","url":"https://www.academia.edu/Documents/in/PCSK9"},{"id":2164652,"name":"Ezetimibe","url":"https://www.academia.edu/Documents/in/Ezetimibe"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-30659717-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="15140595"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/15140595/Changes_in_secondary_prevention_of_coronary_artery_disease_in_the_post_discharge_period_over_the_decade_1997_2007_Results_of_the_Cracovian_Program_for_Secondary_Prevention_of_Ischaemic_Heart_Disease_and_Polish_parts_of_the_EUROASPIRE_II_and_III_surveys"><img alt="Research paper thumbnail of Changes in secondary prevention of coronary artery disease in the post-discharge period over the decade 1997-2007. Results of the Cracovian Program for Secondary Prevention of Ischaemic Heart Disease and Polish parts of the EUROASPIRE II and III surveys" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title">Changes in secondary prevention of coronary artery disease in the post-discharge period over the decade 1997-2007. Results of the Cracovian Program for Secondary Prevention of Ischaemic Heart Disease and Polish parts of the EUROASPIRE II and III surveys</div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/S%C5%82awomirSurowiec">Sławomir Surowiec</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a></span></div><div class="wp-workCard_item"><span>Kardiologia polska</span><span>, 2009</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Both in the European and Polish guidelines, the highest priority for preventive cardiology was gi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Both in the European and Polish guidelines, the highest priority for preventive cardiology was given to patients with established coronary artery disease (CAD). The Cracovian Program for Secondary Prevention of Ischaemic Heart Disease was introduced in 1996 to assess and improve the quality of clinical care in secondary prevention. Departments of cardiology of five participating hospitals serving the area of the city of Kraków and surrounding districts (former Kraków Voivodship) inhabited by a population of 1 200 000 took part in the surveys. In 1999/2000 and 2006/2007 the same hospitals joined the EUROASPIRE (European Action on Secondary Prevention through Intervention to Reduce Events) II and III surveys. The goal of the EUROASPIRE surveys was to assess to what extent the recommendations of the Joint Task Force of International Scientific Societies were implemented into clinical practice. To compare the quality of secondary prevention in the post-discharge period in Kraków in 1997...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="15140595"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="15140595"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 15140595; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=15140595]").text(description); $(".js-view-count[data-work-id=15140595]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 15140595; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='15140595']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=15140595]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":15140595,"title":"Changes in secondary prevention of coronary artery disease in the post-discharge period over the decade 1997-2007. 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In 1999/2000 and 2006/2007 the same hospitals joined the EUROASPIRE (European Action on Secondary Prevention through Intervention to Reduce Events) II and III surveys. The goal of the EUROASPIRE surveys was to assess to what extent the recommendations of the Joint Task Force of International Scientific Societies were implemented into clinical practice. 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Departments of cardiology of five participating hospitals serving the area of the city of Kraków and surrounding districts (former Kraków Voivodship) inhabited by a population of 1 200 000 took part in the surveys. In 1999/2000 and 2006/2007 the same hospitals joined the EUROASPIRE (European Action on Secondary Prevention through Intervention to Reduce Events) II and III surveys. The goal of the EUROASPIRE surveys was to assess to what extent the recommendations of the Joint Task Force of International Scientific Societies were implemented into clinical practice. To compare the quality of secondary prevention in the post-discharge period in Kraków in 1997...","owner":{"id":34178405,"first_name":"Sławomir","middle_initials":"","last_name":"Surowiec","page_name":"SławomirSurowiec","domain_name":"independent","created_at":"2015-08-24T03:48:31.118-07:00","display_name":"Sławomir Surowiec","url":"https://independent.academia.edu/S%C5%82awomirSurowiec"},"attachments":[],"research_interests":[{"id":7471,"name":"Life Style","url":"https://www.academia.edu/Documents/in/Life_Style"},{"id":27363,"name":"Poland","url":"https://www.academia.edu/Documents/in/Poland"},{"id":28973,"name":"Comorbidity","url":"https://www.academia.edu/Documents/in/Comorbidity"},{"id":130343,"name":"Hypercholesterolemia","url":"https://www.academia.edu/Documents/in/Hypercholesterolemia"},{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies"},{"id":167876,"name":"Myocardial Revascularization","url":"https://www.academia.edu/Documents/in/Myocardial_Revascularization"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":789977,"name":"Coronary Artery Disease","url":"https://www.academia.edu/Documents/in/Coronary_Artery_Disease"},{"id":1200766,"name":"Drug Utilization","url":"https://www.academia.edu/Documents/in/Drug_Utilization"},{"id":1246554,"name":"SECONDARY PREVENTION","url":"https://www.academia.edu/Documents/in/SECONDARY_PREVENTION"},{"id":1786368,"name":"Kardiologia","url":"https://www.academia.edu/Documents/in/Kardiologia"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-15140595-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="15140592"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/15140592/Half_of_coronary_patients_are_not_instructed_how_to_respond_to_symptoms_of_a_heart_attack"><img alt="Research paper thumbnail of Half of coronary patients are not instructed how to respond to symptoms of a heart attack" class="work-thumbnail" src="https://attachments.academia-assets.com/43538921/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/15140592/Half_of_coronary_patients_are_not_instructed_how_to_respond_to_symptoms_of_a_heart_attack">Half of coronary patients are not instructed how to respond to symptoms of a heart attack</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/S%C5%82awomirSurowiec">Sławomir Surowiec</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a></span></div><div class="wp-workCard_item"><span>Cardiology Journal</span><span>, 2011</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The delayed treatment of acute coronary syndrome has a significant impact on survival. Due to imp...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The delayed treatment of acute coronary syndrome has a significant impact on survival. Due to improved organization and the use of reperfusion therapies, inhospital delay has been shortened in recent years. However, the time between the onset of chest pain and the call for medical help is still too long. The aim of this study was to assess the proportion of coronary patients instructed how to behave in case of chest pain and to find what factors relate to a lower probability of being counselled.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="7bbfb6129b6056dd35a55080d30e32d4" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":43538921,"asset_id":15140592,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/43538921/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="15140592"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="15140592"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 15140592; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=15140592]").text(description); $(".js-view-count[data-work-id=15140592]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 15140592; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='15140592']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "7bbfb6129b6056dd35a55080d30e32d4" } } $('.js-work-strip[data-work-id=15140592]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":15140592,"title":"Half of coronary patients are not instructed how to respond to symptoms of a heart attack","translated_title":"","metadata":{"ai_title_tag":"Many Coronary Patients Lack Guidance on Heart Attack Response","grobid_abstract":"The delayed treatment of acute coronary syndrome has a significant impact on survival. Due to improved organization and the use of reperfusion therapies, inhospital delay has been shortened in recent years. However, the time between the onset of chest pain and the call for medical help is still too long. The aim of this study was to assess the proportion of coronary patients instructed how to behave in case of chest pain and to find what factors relate to a lower probability of being counselled.","publication_date":{"day":null,"month":null,"year":2011,"errors":{}},"publication_name":"Cardiology Journal","grobid_abstract_attachment_id":43538921},"translated_abstract":null,"internal_url":"https://www.academia.edu/15140592/Half_of_coronary_patients_are_not_instructed_how_to_respond_to_symptoms_of_a_heart_attack","translated_internal_url":"","created_at":"2015-08-24T03:49:07.838-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":34178405,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":4985776,"work_id":15140592,"tagging_user_id":34178405,"tagged_user_id":33097976,"co_author_invite_id":null,"email":"p***i@interia.pl","affiliation":"Jagiellonian University in Krakow","display_order":0,"name":"P. Jankowski","title":"Half of coronary patients are not instructed how to respond to symptoms of a heart attack"},{"id":4985782,"work_id":15140592,"tagging_user_id":34178405,"tagged_user_id":null,"co_author_invite_id":787307,"email":"m***k@cyf-kr.edu.pl","display_order":4194304,"name":"Kalina Kawecka-jaszcz","title":"Half of coronary patients are not instructed how to respond to symptoms of a heart attack"}],"downloadable_attachments":[{"id":43538921,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/43538921/thumbnails/1.jpg","file_name":"Half_of_coronary_patients_are_not_instru20160309-24861-16rucda.pdf","download_url":"https://www.academia.edu/attachments/43538921/download_file","bulk_download_file_name":"Half_of_coronary_patients_are_not_instru.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/43538921/Half_of_coronary_patients_are_not_instru20160309-24861-16rucda-libre.pdf?1457521559=\u0026response-content-disposition=attachment%3B+filename%3DHalf_of_coronary_patients_are_not_instru.pdf\u0026Expires=1743675856\u0026Signature=Ocvc8vY4rdNRUFHjNWJZlMjH3ynN~J1jEfsIZFGpde7spXV0Sr6Q4PCl-t8utTEULS5TsW3j7krZWmRl5NbyEMNTWLHP67EpfK7rNnEJrMsFFCbyThFT747f7MRqQY0Mp2tEsici0vJ5hoTZqun44qc-bHchqJqsZ-v9mj16XNSLfuzwxod0anN7u5Z-FC6CWn93K5K9f3W~enfa0qEoaDtoPYoLMe2IT80gpBqcMH~AKPZjxdmO19s3Is1LG7flNLMkycgXKXb7ioLsVLO27uAOswgR1Auwg9ETMe~5~nr9~mGQoR02k9Xpv3uL1cOyKbr41RJdQioCyKXoqJZx1g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Half_of_coronary_patients_are_not_instructed_how_to_respond_to_symptoms_of_a_heart_attack","translated_slug":"","page_count":7,"language":"en","content_type":"Work","summary":"The delayed treatment of acute coronary syndrome has a significant impact on survival. Due to improved organization and the use of reperfusion therapies, inhospital delay has been shortened in recent years. However, the time between the onset of chest pain and the call for medical help is still too long. The aim of this study was to assess the proportion of coronary patients instructed how to behave in case of chest pain and to find what factors relate to a lower probability of being counselled.","owner":{"id":34178405,"first_name":"Sławomir","middle_initials":"","last_name":"Surowiec","page_name":"SławomirSurowiec","domain_name":"independent","created_at":"2015-08-24T03:48:31.118-07:00","display_name":"Sławomir Surowiec","url":"https://independent.academia.edu/S%C5%82awomirSurowiec"},"attachments":[{"id":43538921,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/43538921/thumbnails/1.jpg","file_name":"Half_of_coronary_patients_are_not_instru20160309-24861-16rucda.pdf","download_url":"https://www.academia.edu/attachments/43538921/download_file","bulk_download_file_name":"Half_of_coronary_patients_are_not_instru.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/43538921/Half_of_coronary_patients_are_not_instru20160309-24861-16rucda-libre.pdf?1457521559=\u0026response-content-disposition=attachment%3B+filename%3DHalf_of_coronary_patients_are_not_instru.pdf\u0026Expires=1743675856\u0026Signature=Ocvc8vY4rdNRUFHjNWJZlMjH3ynN~J1jEfsIZFGpde7spXV0Sr6Q4PCl-t8utTEULS5TsW3j7krZWmRl5NbyEMNTWLHP67EpfK7rNnEJrMsFFCbyThFT747f7MRqQY0Mp2tEsici0vJ5hoTZqun44qc-bHchqJqsZ-v9mj16XNSLfuzwxod0anN7u5Z-FC6CWn93K5K9f3W~enfa0qEoaDtoPYoLMe2IT80gpBqcMH~AKPZjxdmO19s3Is1LG7flNLMkycgXKXb7ioLsVLO27uAOswgR1Auwg9ETMe~5~nr9~mGQoR02k9Xpv3uL1cOyKbr41RJdQioCyKXoqJZx1g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology"},{"id":1048,"name":"Health Behavior","url":"https://www.academia.edu/Documents/in/Health_Behavior"},{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment"},{"id":27363,"name":"Poland","url":"https://www.academia.edu/Documents/in/Poland"},{"id":96213,"name":"Hospitalization","url":"https://www.academia.edu/Documents/in/Hospitalization"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":300876,"name":"Acute Coronary Syndrome","url":"https://www.academia.edu/Documents/in/Acute_Coronary_Syndrome"},{"id":327850,"name":"Questionnaires","url":"https://www.academia.edu/Documents/in/Questionnaires"},{"id":398808,"name":"Coronary heart disease","url":"https://www.academia.edu/Documents/in/Coronary_heart_disease"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies"},{"id":479871,"name":"Angina pectoris","url":"https://www.academia.edu/Documents/in/Angina_pectoris"},{"id":584601,"name":"Chi Square Distribution","url":"https://www.academia.edu/Documents/in/Chi_Square_Distribution"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1"},{"id":622589,"name":"Risk Assessment","url":"https://www.academia.edu/Documents/in/Risk_Assessment-2"},{"id":1294607,"name":"Logistic Models","url":"https://www.academia.edu/Documents/in/Logistic_Models"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-15140592-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="15068554"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/15068554/Udro%C5%BCnienia_przewlek%C5%82ych_okluzji_t%C4%99tnic_wie%C5%84cowych_metod%C4%85_wsteczn%C4%85_pierwsze_polskie_do%C5%9Bwiadczenia"><img alt="Research paper thumbnail of Udrożnienia przewlekłych okluzji tętnic wieńcowych metodą wsteczną: pierwsze polskie doświadczenia" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title">Udrożnienia przewlekłych okluzji tętnic wieńcowych metodą wsteczną: pierwsze polskie doświadczenia</div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/TadeuszKr%C3%B3likowski">Tadeusz Królikowski</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/S%C5%82awomirSurowiec">Sławomir Surowiec</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://jagiellonian.academia.edu/PiotrKusak">Piotr Kusak</a></span></div><div class="wp-workCard_item"><span>Kardiologia Polska</span><span>, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The effectiveness of revascularisation procedures of coronary chronic total occlusion (CTO) has b...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The effectiveness of revascularisation procedures of coronary chronic total occlusion (CTO) has been improved by the introduction of retrograde approach. This study compared the outcomes of CTO revascularisation in a single centre in Krakow, Poland using antegrade and retrograde approach. From January 2011 to September 2013, 150 patients underwent 159 procedures for percutaneous revascularisation of CTO of 153 vessels. Of the 159 procedures, 124 (78%) were performed using an antegrade approach and 35 (22%) using a retrograde approach. All patients were symptomatic, with mean CCS class (2.3 ± 0.6 vs. 2.1 ± 0.7, p = 0.9), mean age (59.2 ± 8.3 vs. 62.6 ± 9.9 years, p = 0.067), and mean number of males (81.3% vs. 81.8%, p = 0.9) similar in the retrograde and antegrade groups, respectively. Most patients in both groups had ejection fraction (EF) ≥ 50% (84.4% vs. 74.4%, respectively). Occlusions assessed according to the J-CTO score showed that 82.9% and 56.4%, respectively, were rated as difficult or very difficult (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). Overall procedural success rate was 88.2%, 87.9% in the antegrade, and 74.3% in the retrograde group. Complication rates were low and similar in two groups. However, the retrograde approach was associated with a longer mean fluoroscopy time (47.8 ± 19.6 vs. 19.3 ± 10.0 min, p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.00001) and higher volume of contrast fluid (494.6 ± 142.4 vs. 291.9 ± 118.1 mL, p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.00001). Using novel equipment with adequate experience allowed high rates of successful revascularisation. The retrograde technique for CTO revascularisation showed good overall success and was safe.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="15068554"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="15068554"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 15068554; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=15068554]").text(description); $(".js-view-count[data-work-id=15068554]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 15068554; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='15068554']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=15068554]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":15068554,"title":"Udrożnienia przewlekłych okluzji tętnic wieńcowych metodą wsteczną: pierwsze polskie doświadczenia","translated_title":"","metadata":{"abstract":"The effectiveness of revascularisation procedures of coronary chronic total occlusion (CTO) has been improved by the introduction of retrograde approach. This study compared the outcomes of CTO revascularisation in a single centre in Krakow, Poland using antegrade and retrograde approach. From January 2011 to September 2013, 150 patients underwent 159 procedures for percutaneous revascularisation of CTO of 153 vessels. Of the 159 procedures, 124 (78%) were performed using an antegrade approach and 35 (22%) using a retrograde approach. All patients were symptomatic, with mean CCS class (2.3 ± 0.6 vs. 2.1 ± 0.7, p = 0.9), mean age (59.2 ± 8.3 vs. 62.6 ± 9.9 years, p = 0.067), and mean number of males (81.3% vs. 81.8%, p = 0.9) similar in the retrograde and antegrade groups, respectively. Most patients in both groups had ejection fraction (EF) ≥ 50% (84.4% vs. 74.4%, respectively). Occlusions assessed according to the J-CTO score showed that 82.9% and 56.4%, respectively, were rated as difficult or very difficult (p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). Overall procedural success rate was 88.2%, 87.9% in the antegrade, and 74.3% in the retrograde group. Complication rates were low and similar in two groups. However, the retrograde approach was associated with a longer mean fluoroscopy time (47.8 ± 19.6 vs. 19.3 ± 10.0 min, p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.00001) and higher volume of contrast fluid (494.6 ± 142.4 vs. 291.9 ± 118.1 mL, p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.00001). Using novel equipment with adequate experience allowed high rates of successful revascularisation. The retrograde technique for CTO revascularisation showed good overall success and was safe.","publication_date":{"day":null,"month":null,"year":2015,"errors":{}},"publication_name":"Kardiologia Polska"},"translated_abstract":"The effectiveness of revascularisation procedures of coronary chronic total occlusion (CTO) has been improved by the introduction of retrograde approach. This study compared the outcomes of CTO revascularisation in a single centre in Krakow, Poland using antegrade and retrograde approach. From January 2011 to September 2013, 150 patients underwent 159 procedures for percutaneous revascularisation of CTO of 153 vessels. Of the 159 procedures, 124 (78%) were performed using an antegrade approach and 35 (22%) using a retrograde approach. All patients were symptomatic, with mean CCS class (2.3 ± 0.6 vs. 2.1 ± 0.7, p = 0.9), mean age (59.2 ± 8.3 vs. 62.6 ± 9.9 years, p = 0.067), and mean number of males (81.3% vs. 81.8%, p = 0.9) similar in the retrograde and antegrade groups, respectively. Most patients in both groups had ejection fraction (EF) ≥ 50% (84.4% vs. 74.4%, respectively). Occlusions assessed according to the J-CTO score showed that 82.9% and 56.4%, respectively, were rated as difficult or very difficult (p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). Overall procedural success rate was 88.2%, 87.9% in the antegrade, and 74.3% in the retrograde group. Complication rates were low and similar in two groups. However, the retrograde approach was associated with a longer mean fluoroscopy time (47.8 ± 19.6 vs. 19.3 ± 10.0 min, p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.00001) and higher volume of contrast fluid (494.6 ± 142.4 vs. 291.9 ± 118.1 mL, p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.00001). Using novel equipment with adequate experience allowed high rates of successful revascularisation. The retrograde technique for CTO revascularisation showed good overall success and was safe.","internal_url":"https://www.academia.edu/15068554/Udro%C5%BCnienia_przewlek%C5%82ych_okluzji_t%C4%99tnic_wie%C5%84cowych_metod%C4%85_wsteczn%C4%85_pierwsze_polskie_do%C5%9Bwiadczenia","translated_internal_url":"","created_at":"2015-08-21T00:42:30.785-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":34098823,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":4879886,"work_id":15068554,"tagging_user_id":34098823,"tagged_user_id":33064983,"co_author_invite_id":null,"email":"l***i@poczta.fm","display_order":0,"name":"Leszek Bryniarski","title":"Udrożnienia przewlekłych okluzji tętnic wieńcowych metodą wsteczną: pierwsze polskie doświadczenia"},{"id":4879890,"work_id":15068554,"tagging_user_id":34098823,"tagged_user_id":33097976,"co_author_invite_id":null,"email":"p***i@interia.pl","affiliation":"Jagiellonian University in Krakow","display_order":4194304,"name":"P. Jankowski","title":"Udrożnienia przewlekłych okluzji tętnic wieńcowych metodą wsteczną: pierwsze polskie doświadczenia"},{"id":4879893,"work_id":15068554,"tagging_user_id":34098823,"tagged_user_id":34036833,"co_author_invite_id":null,"email":"r***7@interia.pl","display_order":6291456,"name":"Marek Rajzer","title":"Udrożnienia przewlekłych okluzji tętnic wieńcowych metodą wsteczną: pierwsze polskie doświadczenia"},{"id":4879900,"work_id":15068554,"tagging_user_id":34098823,"tagged_user_id":34178405,"co_author_invite_id":1108757,"email":"s***c@wp.pl","display_order":7340032,"name":"Sławomir Surowiec","title":"Udrożnienia przewlekłych okluzji tętnic wieńcowych metodą wsteczną: pierwsze polskie doświadczenia"},{"id":4879901,"work_id":15068554,"tagging_user_id":34098823,"tagged_user_id":34259336,"co_author_invite_id":1108758,"email":"k***r@gmail.com","affiliation":"Jagiellonian University","display_order":7864320,"name":"Piotr Kusak","title":"Udrożnienia przewlekłych okluzji tętnic wieńcowych metodą wsteczną: pierwsze polskie doświadczenia"},{"id":4879902,"work_id":15068554,"tagging_user_id":34098823,"tagged_user_id":null,"co_author_invite_id":757268,"email":"m***a@kinga.cyf-kr.edu.pl","display_order":8126464,"name":"Krzysztof Żmudka","title":"Udrożnienia przewlekłych okluzji tętnic wieńcowych metodą wsteczną: pierwsze polskie doświadczenia"},{"id":4879903,"work_id":15068554,"tagging_user_id":34098823,"tagged_user_id":null,"co_author_invite_id":757274,"email":"m***k@cyfr-kr.edu.pl","display_order":8257536,"name":"Dariusz Dudek","title":"Udrożnienia przewlekłych okluzji tętnic wieńcowych metodą wsteczną: pierwsze polskie doświadczenia"}],"downloadable_attachments":[],"slug":"Udrożnienia_przewlekłych_okluzji_tętnic_wieńcowych_metodą_wsteczną_pierwsze_polskie_doświadczenia","translated_slug":"","page_count":null,"language":"en","content_type":"Work","summary":"The effectiveness of revascularisation procedures of coronary chronic total occlusion (CTO) has been improved by the introduction of retrograde approach. This study compared the outcomes of CTO revascularisation in a single centre in Krakow, Poland using antegrade and retrograde approach. From January 2011 to September 2013, 150 patients underwent 159 procedures for percutaneous revascularisation of CTO of 153 vessels. Of the 159 procedures, 124 (78%) were performed using an antegrade approach and 35 (22%) using a retrograde approach. All patients were symptomatic, with mean CCS class (2.3 ± 0.6 vs. 2.1 ± 0.7, p = 0.9), mean age (59.2 ± 8.3 vs. 62.6 ± 9.9 years, p = 0.067), and mean number of males (81.3% vs. 81.8%, p = 0.9) similar in the retrograde and antegrade groups, respectively. Most patients in both groups had ejection fraction (EF) ≥ 50% (84.4% vs. 74.4%, respectively). Occlusions assessed according to the J-CTO score showed that 82.9% and 56.4%, respectively, were rated as difficult or very difficult (p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). Overall procedural success rate was 88.2%, 87.9% in the antegrade, and 74.3% in the retrograde group. Complication rates were low and similar in two groups. However, the retrograde approach was associated with a longer mean fluoroscopy time (47.8 ± 19.6 vs. 19.3 ± 10.0 min, p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.00001) and higher volume of contrast fluid (494.6 ± 142.4 vs. 291.9 ± 118.1 mL, p \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.00001). Using novel equipment with adequate experience allowed high rates of successful revascularisation. The retrograde technique for CTO revascularisation showed good overall success and was safe.","owner":{"id":34098823,"first_name":"Tadeusz","middle_initials":null,"last_name":"Królikowski","page_name":"TadeuszKrólikowski","domain_name":"independent","created_at":"2015-08-21T00:41:38.573-07:00","display_name":"Tadeusz Królikowski","url":"https://independent.academia.edu/TadeuszKr%C3%B3likowski"},"attachments":[],"research_interests":[],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-15068554-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="14944118"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/14944118/Polish_Forum_for_Prevention_of_Cardiovascular_Diseases_Guidelines_on_prophylactic_pharmacotherapy"><img alt="Research paper thumbnail of Polish Forum for Prevention of Cardiovascular Diseases Guidelines on prophylactic pharmacotherapy" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title">Polish Forum for Prevention of Cardiovascular Diseases Guidelines on prophylactic pharmacotherapy</div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/WojciechDrygas">Wojciech Drygas</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/AnettaUndas">Anetta Undas</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a></span></div><div class="wp-workCard_item"><span>Kardiologia polska</span><span>, 2011</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">... Podolec P, Kopeć G, Undas A, Pająk A, Godycki-Ćwirko M, Zdrojewski T, Jankowski P, Drygas W, ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">... Podolec P, Kopeć G, Undas A, Pająk A, Godycki-Ćwirko M, Zdrojewski T, Jankowski P, Drygas W, Rynkiewicz A, Piotrowicz R, Czarnecka D, Naruszewicz M, Opala G, Stańczyk J, Kozek E, Windak A, Banasiak W, Guzik T. PMID: 21332073 [PubMed - in process].</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14944118"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14944118"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14944118; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14944118]").text(description); $(".js-view-count[data-work-id=14944118]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14944118; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14944118']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14944118]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14944118,"title":"Polish Forum for Prevention of Cardiovascular Diseases Guidelines on prophylactic pharmacotherapy","translated_title":"","metadata":{"abstract":"... Podolec P, Kopeć G, Undas A, Pająk A, Godycki-Ćwirko M, Zdrojewski T, Jankowski P, Drygas W, Rynkiewicz A, Piotrowicz R, Czarnecka D, Naruszewicz M, Opala G, Stańczyk J, Kozek E, Windak A, Banasiak W, Guzik T. PMID: 21332073 [PubMed - in process].","publication_date":{"day":null,"month":null,"year":2011,"errors":{}},"publication_name":"Kardiologia polska"},"translated_abstract":"... Podolec P, Kopeć G, Undas A, Pająk A, Godycki-Ćwirko M, Zdrojewski T, Jankowski P, Drygas W, Rynkiewicz A, Piotrowicz R, Czarnecka D, Naruszewicz M, Opala G, Stańczyk J, Kozek E, Windak A, Banasiak W, Guzik T. PMID: 21332073 [PubMed - in process].","internal_url":"https://www.academia.edu/14944118/Polish_Forum_for_Prevention_of_Cardiovascular_Diseases_Guidelines_on_prophylactic_pharmacotherapy","translated_internal_url":"","created_at":"2015-08-15T11:18:11.098-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":33935206,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":4676967,"work_id":14944118,"tagging_user_id":33935206,"tagged_user_id":213340266,"co_author_invite_id":1040190,"email":"w***s@ikard.pl","display_order":0,"name":"Wojciech Drygas","title":"Polish Forum for Prevention of Cardiovascular Diseases Guidelines on prophylactic pharmacotherapy"},{"id":4677045,"work_id":14944118,"tagging_user_id":33935206,"tagged_user_id":34020020,"co_author_invite_id":1073339,"email":"p***c@interia.pl","display_order":4194304,"name":"Piotr Podolec","title":"Polish Forum for Prevention of Cardiovascular Diseases Guidelines on prophylactic pharmacotherapy"},{"id":4677075,"work_id":14944118,"tagging_user_id":33935206,"tagged_user_id":null,"co_author_invite_id":775471,"email":"t***k@cm-uj.krakow.pl","display_order":6291456,"name":"T. Guzik","title":"Polish Forum for Prevention of Cardiovascular Diseases Guidelines on prophylactic pharmacotherapy"},{"id":4677082,"work_id":14944118,"tagging_user_id":33935206,"tagged_user_id":null,"co_author_invite_id":808360,"email":"g***c@uj.edu.pl","display_order":7340032,"name":"Grzegorz Kopeć","title":"Polish Forum for Prevention of Cardiovascular Diseases Guidelines on prophylactic pharmacotherapy"},{"id":4677084,"work_id":14944118,"tagging_user_id":33935206,"tagged_user_id":33097976,"co_author_invite_id":null,"email":"p***i@interia.pl","affiliation":"Jagiellonian University in Krakow","display_order":7864320,"name":"P. Jankowski","title":"Polish Forum for Prevention of Cardiovascular Diseases Guidelines on prophylactic pharmacotherapy"}],"downloadable_attachments":[],"slug":"Polish_Forum_for_Prevention_of_Cardiovascular_Diseases_Guidelines_on_prophylactic_pharmacotherapy","translated_slug":"","page_count":null,"language":"pl","content_type":"Work","summary":"... Podolec P, Kopeć G, Undas A, Pająk A, Godycki-Ćwirko M, Zdrojewski T, Jankowski P, Drygas W, Rynkiewicz A, Piotrowicz R, Czarnecka D, Naruszewicz M, Opala G, Stańczyk J, Kozek E, Windak A, Banasiak W, Guzik T. PMID: 21332073 [PubMed - in process].","owner":{"id":33935206,"first_name":"Anetta","middle_initials":null,"last_name":"Undas","page_name":"AnettaUndas","domain_name":"independent","created_at":"2015-08-15T11:17:38.855-07:00","display_name":"Anetta Undas","url":"https://independent.academia.edu/AnettaUndas"},"attachments":[],"research_interests":[{"id":27363,"name":"Poland","url":"https://www.academia.edu/Documents/in/Poland"},{"id":559242,"name":"Cardiovascular Diseases","url":"https://www.academia.edu/Documents/in/Cardiovascular_Diseases"},{"id":1246554,"name":"SECONDARY PREVENTION","url":"https://www.academia.edu/Documents/in/SECONDARY_PREVENTION"},{"id":1786368,"name":"Kardiologia","url":"https://www.academia.edu/Documents/in/Kardiologia"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-14944118-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="15003586"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/15003586/_Percutaneous_coronary_angioplasty_in_acute_myocardial_infarction_in_elderly_patients_"><img alt="Research paper thumbnail of [Percutaneous coronary angioplasty in acute myocardial infarction in elderly patients]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title">[Percutaneous coronary angioplasty in acute myocardial infarction in elderly patients]</div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/JacekDragan">Jacek Dragan</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/TadeuszKr%C3%B3likowski">Tadeusz Królikowski</a></span></div><div class="wp-workCard_item"><span>Kardiologia polska</span><span>, 2004</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Over 1/3 of all patients treated for acute myocardial infarction are elderly (over 70 years of ag...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Over 1/3 of all patients treated for acute myocardial infarction are elderly (over 70 years of age). Blood flow restoration in the infarct-related artery is a fundamental therapeutic strategy, however reperfusion therapy is rarely used in the elderly as compared with younger groups. Mortality and complication rates are much higher in the elderly than in younger patients irrespective of the type of reperfusion therapy. Elderly patients are modestly represented in studies undertaken to analyze the efficacy of various types of reperfusion therapy. For this reason the choice of an optimal therapy in acute myocardial infarction in the elderly remains an open question. In the I Department of Cardiology PCI has been the strategy of choice in the treatment of acute myocardial infarction. This is a retrospective analysis of early and late outcomes of primary coronary angioplasty in elderly patients with myocardial infarction. Between June 2001 and December 2003 four hundred and five (405) co...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="15003586"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="15003586"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 15003586; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=15003586]").text(description); $(".js-view-count[data-work-id=15003586]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 15003586; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='15003586']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=15003586]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":15003586,"title":"[Percutaneous coronary angioplasty in acute myocardial infarction in elderly patients]","translated_title":"","metadata":{"abstract":"Over 1/3 of all patients treated for acute myocardial infarction are elderly (over 70 years of age). Blood flow restoration in the infarct-related artery is a fundamental therapeutic strategy, however reperfusion therapy is rarely used in the elderly as compared with younger groups. Mortality and complication rates are much higher in the elderly than in younger patients irrespective of the type of reperfusion therapy. Elderly patients are modestly represented in studies undertaken to analyze the efficacy of various types of reperfusion therapy. For this reason the choice of an optimal therapy in acute myocardial infarction in the elderly remains an open question. In the I Department of Cardiology PCI has been the strategy of choice in the treatment of acute myocardial infarction. This is a retrospective analysis of early and late outcomes of primary coronary angioplasty in elderly patients with myocardial infarction. Between June 2001 and December 2003 four hundred and five (405) co...","publication_date":{"day":null,"month":null,"year":2004,"errors":{}},"publication_name":"Kardiologia polska"},"translated_abstract":"Over 1/3 of all patients treated for acute myocardial infarction are elderly (over 70 years of age). Blood flow restoration in the infarct-related artery is a fundamental therapeutic strategy, however reperfusion therapy is rarely used in the elderly as compared with younger groups. Mortality and complication rates are much higher in the elderly than in younger patients irrespective of the type of reperfusion therapy. Elderly patients are modestly represented in studies undertaken to analyze the efficacy of various types of reperfusion therapy. For this reason the choice of an optimal therapy in acute myocardial infarction in the elderly remains an open question. In the I Department of Cardiology PCI has been the strategy of choice in the treatment of acute myocardial infarction. This is a retrospective analysis of early and late outcomes of primary coronary angioplasty in elderly patients with myocardial infarction. 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Between June 2001 and December 2003 four hundred and five (405) co...","owner":{"id":34006700,"first_name":"Jacek","middle_initials":null,"last_name":"Dragan","page_name":"JacekDragan","domain_name":"independent","created_at":"2015-08-18T04:16:24.928-07:00","display_name":"Jacek Dragan","url":"https://independent.academia.edu/JacekDragan"},"attachments":[],"research_interests":[{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome"},{"id":147196,"name":"Monoclonal Antibodies","url":"https://www.academia.edu/Documents/in/Monoclonal_Antibodies"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":378016,"name":"Myocardial Infarction","url":"https://www.academia.edu/Documents/in/Myocardial_Infarction"},{"id":424295,"name":"Survival Rate","url":"https://www.academia.edu/Documents/in/Survival_Rate"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies"},{"id":546419,"name":"Age Factors","url":"https://www.academia.edu/Documents/in/Age_Factors"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-15003586-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="15003584"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/15003584/_Acute_myocardial_infarction_complicated_by_cardiogenic_shock_treated_with_angioplasty_of_left_main_stenosis_two_case_reports_"><img alt="Research paper thumbnail of [Acute myocardial infarction complicated by cardiogenic shock treated with angioplasty of left main stenosis - two case reports]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title">[Acute myocardial infarction complicated by cardiogenic shock treated with angioplasty of left main stenosis - two case reports]</div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/JacekDragan">Jacek Dragan</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a></span></div><div class="wp-workCard_item"><span>Kardiologia polska</span><span>, 2002</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Two patients with acute myocardial infarction (MI) complicated by cardiogenic shock are described...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Two patients with acute myocardial infarction (MI) complicated by cardiogenic shock are described. Coronary angiography revealed subtotal left main stenosis. Both patients underwent successful primary coronary angioplasty. 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Jankowski</a></span></div><div class="wp-workCard_item"><span>Journal of Human Hypertension</span><span>, 2002</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Arterial pathology is a major contributor to cardiovascular disease, morbidity and mortality. Wom...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Arterial pathology is a major contributor to cardiovascular disease, morbidity and mortality. Women are at higher risk of cardiovascular disease after menopause. Arterial stiffness determined by pulse wave velocity, increases with age both in men and women, whereas arterial compliance in premenopausal women is greater than in men of similar age. 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Jankowski</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/TadeuszKr%C3%B3likowski">Tadeusz Królikowski</a></span></div><div class="wp-workCard_item"><span>Przegla̧d lekarski</span><span>, 2002</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">In patients following a myocardial infarction, heart rate variability is an important prognostic ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">In patients following a myocardial infarction, heart rate variability is an important prognostic factor. Decreased heart rate variability is associated with a higher mortality rate. This study evaluated the influence of recanalisation by percutaneous coronary intervention (PCI) in totally occluded coronary arteries on the heart rate variability in patients with myocardial akinesis in the recanalised artery area. The study group included 22 men (average age 52.8 +/- 7.7) after successful PCI recanalization of the totally occluded artery. All patients had akinesis in the recanalised artery area. All patients underwent 24-hour continuous electrocardiographic Holter monitoring with HRV analysis and echocardiographic dobutamine tests both before the PCI and 6 months afterwards. The population was divided into two groups: group A (10 patients) had contractility adjustments in echocardiographic tests that were performed 6 months after the PCI. Group B (12 patients) did not have contractili...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="15003587"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="15003587"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 15003587; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=15003587]").text(description); $(".js-view-count[data-work-id=15003587]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 15003587; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='15003587']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=15003587]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":15003587,"title":"[The influence of percutaneous coronary recanalization of total coronary occlusions on the heart rate variability ]","translated_title":"","metadata":{"abstract":"In patients following a myocardial infarction, heart rate variability is an important prognostic factor. Decreased heart rate variability is associated with a higher mortality rate. This study evaluated the influence of recanalisation by percutaneous coronary intervention (PCI) in totally occluded coronary arteries on the heart rate variability in patients with myocardial akinesis in the recanalised artery area. The study group included 22 men (average age 52.8 +/- 7.7) after successful PCI recanalization of the totally occluded artery. All patients had akinesis in the recanalised artery area. All patients underwent 24-hour continuous electrocardiographic Holter monitoring with HRV analysis and echocardiographic dobutamine tests both before the PCI and 6 months afterwards. The population was divided into two groups: group A (10 patients) had contractility adjustments in echocardiographic tests that were performed 6 months after the PCI. Group B (12 patients) did not have contractili...","publication_date":{"day":null,"month":null,"year":2002,"errors":{}},"publication_name":"Przegla̧d lekarski"},"translated_abstract":"In patients following a myocardial infarction, heart rate variability is an important prognostic factor. Decreased heart rate variability is associated with a higher mortality rate. This study evaluated the influence of recanalisation by percutaneous coronary intervention (PCI) in totally occluded coronary arteries on the heart rate variability in patients with myocardial akinesis in the recanalised artery area. The study group included 22 men (average age 52.8 +/- 7.7) after successful PCI recanalization of the totally occluded artery. All patients had akinesis in the recanalised artery area. All patients underwent 24-hour continuous electrocardiographic Holter monitoring with HRV analysis and echocardiographic dobutamine tests both before the PCI and 6 months afterwards. The population was divided into two groups: group A (10 patients) had contractility adjustments in echocardiographic tests that were performed 6 months after the PCI. Group B (12 patients) did not have contractili...","internal_url":"https://www.academia.edu/15003587/_The_influence_of_percutaneous_coronary_recanalization_of_total_coronary_occlusions_on_the_heart_rate_variability_","translated_internal_url":"","created_at":"2015-08-18T04:18:01.060-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":34006700,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":4777799,"work_id":15003587,"tagging_user_id":34006700,"tagged_user_id":null,"co_author_invite_id":757212,"email":"a***a@poczta.onet.pl","display_order":0,"name":"Artur Klecha","title":"[The influence of percutaneous coronary recanalization of total coronary occlusions on the heart rate variability ]"},{"id":4777804,"work_id":15003587,"tagging_user_id":34006700,"tagged_user_id":33097976,"co_author_invite_id":null,"email":"p***i@interia.pl","affiliation":"Jagiellonian University in Krakow","display_order":4194304,"name":"P. 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Decreased heart rate variability is associated with a higher mortality rate. This study evaluated the influence of recanalisation by percutaneous coronary intervention (PCI) in totally occluded coronary arteries on the heart rate variability in patients with myocardial akinesis in the recanalised artery area. The study group included 22 men (average age 52.8 +/- 7.7) after successful PCI recanalization of the totally occluded artery. All patients had akinesis in the recanalised artery area. All patients underwent 24-hour continuous electrocardiographic Holter monitoring with HRV analysis and echocardiographic dobutamine tests both before the PCI and 6 months afterwards. The population was divided into two groups: group A (10 patients) had contractility adjustments in echocardiographic tests that were performed 6 months after the PCI. Group B (12 patients) did not have contractili...","owner":{"id":34006700,"first_name":"Jacek","middle_initials":null,"last_name":"Dragan","page_name":"JacekDragan","domain_name":"independent","created_at":"2015-08-18T04:16:24.928-07:00","display_name":"Jacek Dragan","url":"https://independent.academia.edu/JacekDragan"},"attachments":[],"research_interests":[{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome"},{"id":131298,"name":"Heart rate","url":"https://www.academia.edu/Documents/in/Heart_rate"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":378016,"name":"Myocardial Infarction","url":"https://www.academia.edu/Documents/in/Myocardial_Infarction"},{"id":398808,"name":"Coronary heart disease","url":"https://www.academia.edu/Documents/in/Coronary_heart_disease"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-15003587-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="14031704"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/14031704/PREDICTIVE_VALUE_OF_CENTRAL_SYSTOLIC_AND_DIASTOLIC_PRESSURE_IN_CORONARY_PATIENTS_RESULTS_FROM_THE_AORTIC_BLOOD_PRESSURE_AND_SURVIVAL_STUDY_3A_04"><img alt="Research paper thumbnail of PREDICTIVE VALUE OF CENTRAL SYSTOLIC AND DIASTOLIC PRESSURE IN CORONARY PATIENTS. RESULTS FROM THE AORTIC BLOOD PRESSURE AND SURVIVAL STUDY: 3A.04" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title">PREDICTIVE VALUE OF CENTRAL SYSTOLIC AND DIASTOLIC PRESSURE IN CORONARY PATIENTS. RESULTS FROM THE AORTIC BLOOD PRESSURE AND SURVIVAL STUDY: 3A.04</div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/JerzyWili%C5%84ski">Jerzy Wiliński</a></span></div><div class="wp-workCard_item"><span>Journal of Hypertension</span><span>, 2010</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">ABSTRACT Background and Aims: Besides its known cardiac effects, cardiotrophin-1 (CT-1), a cytoki...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">ABSTRACT Background and Aims: Besides its known cardiac effects, cardiotrophin-1 (CT-1), a cytokine belonging to the interleukin-6 family, exerts proliferative and secretory effects in vascular smooth muscle cells. We aimed to investigate the functional and morphological vascular changes induced by chronic CT-1 administration in rats and its involvement in the arterial phenotype of CT-1-null mice in vivo. Methods: A) Recombinant rat CT-1 (20 μg/Kg, IP) was administrated to Wistar rats for six weeks (n = 10/group). Blood pressure (BP) and heart rate were recorded by telemetry. Cardiac function was assessed using PET-scan. B) 2 year-old wild-type (WT) (n = 8) and CT-1-null mice (n = 3) were studied. Vascular structure and function were evaluated by an echo-tracking device. Circumferential wall stress, incremental elastic modulus (Einc), media cross-sectional area and pulse wave velocity (PWV) were measured. Aortic wall collagen and elastin contents were determined using immunohistochemistry, and the expression of collagen type I and III, elastin and fibronectin was quantified by RT-PCR and Western blot in aortic extracts. Results: A) Neither vehicle nor CT-1 treatment modified BP. CT-1-treated rats displayed decreased cardiac output (p &amp;lt; 0.01) as well as wall stress (p &amp;lt; 0.01), Einc (p &amp;lt; 0.01) and PWV (p &amp;lt; 0.05) as compared with vehicle group. CT-1-treated rats also showed increased media cross sectional area (p &amp;lt; 0.01) and collagen content (p &amp;lt; 0.01). CT-1-overloaded rats displayed increased expression of collagen type I (p &amp;lt; 0.05) and III (p &amp;lt; 0.01) and fibronectin (p &amp;lt; 0.01). B) CT-1-null mice presented an increased wall stress (p &amp;lt; 0.05) and Einc (p &amp;lt; 0.05) as compared with WT mice. Media cross sectional area and collagen content were reduced (p &amp;lt; 0.05) in mice lacking CT-1. Conclusions: Normotensive rats subjected to CT-1 overloading developed impaired cardiac and vascular functions, characterized by an increment in arterial stiffness accompanied by an augmented media thickness and extracellular matrix production. Accordingly, CT-1-null mice presented a reduced arterial stiffness and a reduced media thickness and collagen content. Our data show that CT-1 is a key player in arterial thickness and stiffness and in the cardiovascular coupling.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14031704"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14031704"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14031704; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14031704]").text(description); $(".js-view-count[data-work-id=14031704]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14031704; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14031704']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14031704]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14031704,"title":"PREDICTIVE VALUE OF CENTRAL SYSTOLIC AND DIASTOLIC PRESSURE IN CORONARY PATIENTS. RESULTS FROM THE AORTIC BLOOD PRESSURE AND SURVIVAL STUDY: 3A.04","translated_title":"","metadata":{"abstract":"ABSTRACT Background and Aims: Besides its known cardiac effects, cardiotrophin-1 (CT-1), a cytokine belonging to the interleukin-6 family, exerts proliferative and secretory effects in vascular smooth muscle cells. We aimed to investigate the functional and morphological vascular changes induced by chronic CT-1 administration in rats and its involvement in the arterial phenotype of CT-1-null mice in vivo. Methods: A) Recombinant rat CT-1 (20 μg/Kg, IP) was administrated to Wistar rats for six weeks (n = 10/group). Blood pressure (BP) and heart rate were recorded by telemetry. Cardiac function was assessed using PET-scan. B) 2 year-old wild-type (WT) (n = 8) and CT-1-null mice (n = 3) were studied. Vascular structure and function were evaluated by an echo-tracking device. Circumferential wall stress, incremental elastic modulus (Einc), media cross-sectional area and pulse wave velocity (PWV) were measured. Aortic wall collagen and elastin contents were determined using immunohistochemistry, and the expression of collagen type I and III, elastin and fibronectin was quantified by RT-PCR and Western blot in aortic extracts. Results: A) Neither vehicle nor CT-1 treatment modified BP. CT-1-treated rats displayed decreased cardiac output (p \u0026amp;lt; 0.01) as well as wall stress (p \u0026amp;lt; 0.01), Einc (p \u0026amp;lt; 0.01) and PWV (p \u0026amp;lt; 0.05) as compared with vehicle group. CT-1-treated rats also showed increased media cross sectional area (p \u0026amp;lt; 0.01) and collagen content (p \u0026amp;lt; 0.01). CT-1-overloaded rats displayed increased expression of collagen type I (p \u0026amp;lt; 0.05) and III (p \u0026amp;lt; 0.01) and fibronectin (p \u0026amp;lt; 0.01). B) CT-1-null mice presented an increased wall stress (p \u0026amp;lt; 0.05) and Einc (p \u0026amp;lt; 0.05) as compared with WT mice. Media cross sectional area and collagen content were reduced (p \u0026amp;lt; 0.05) in mice lacking CT-1. Conclusions: Normotensive rats subjected to CT-1 overloading developed impaired cardiac and vascular functions, characterized by an increment in arterial stiffness accompanied by an augmented media thickness and extracellular matrix production. Accordingly, CT-1-null mice presented a reduced arterial stiffness and a reduced media thickness and collagen content. Our data show that CT-1 is a key player in arterial thickness and stiffness and in the cardiovascular coupling.","publication_date":{"day":null,"month":null,"year":2010,"errors":{}},"publication_name":"Journal of Hypertension"},"translated_abstract":"ABSTRACT Background and Aims: Besides its known cardiac effects, cardiotrophin-1 (CT-1), a cytokine belonging to the interleukin-6 family, exerts proliferative and secretory effects in vascular smooth muscle cells. We aimed to investigate the functional and morphological vascular changes induced by chronic CT-1 administration in rats and its involvement in the arterial phenotype of CT-1-null mice in vivo. Methods: A) Recombinant rat CT-1 (20 μg/Kg, IP) was administrated to Wistar rats for six weeks (n = 10/group). Blood pressure (BP) and heart rate were recorded by telemetry. Cardiac function was assessed using PET-scan. B) 2 year-old wild-type (WT) (n = 8) and CT-1-null mice (n = 3) were studied. Vascular structure and function were evaluated by an echo-tracking device. Circumferential wall stress, incremental elastic modulus (Einc), media cross-sectional area and pulse wave velocity (PWV) were measured. Aortic wall collagen and elastin contents were determined using immunohistochemistry, and the expression of collagen type I and III, elastin and fibronectin was quantified by RT-PCR and Western blot in aortic extracts. Results: A) Neither vehicle nor CT-1 treatment modified BP. CT-1-treated rats displayed decreased cardiac output (p \u0026amp;lt; 0.01) as well as wall stress (p \u0026amp;lt; 0.01), Einc (p \u0026amp;lt; 0.01) and PWV (p \u0026amp;lt; 0.05) as compared with vehicle group. CT-1-treated rats also showed increased media cross sectional area (p \u0026amp;lt; 0.01) and collagen content (p \u0026amp;lt; 0.01). CT-1-overloaded rats displayed increased expression of collagen type I (p \u0026amp;lt; 0.05) and III (p \u0026amp;lt; 0.01) and fibronectin (p \u0026amp;lt; 0.01). B) CT-1-null mice presented an increased wall stress (p \u0026amp;lt; 0.05) and Einc (p \u0026amp;lt; 0.05) as compared with WT mice. Media cross sectional area and collagen content were reduced (p \u0026amp;lt; 0.05) in mice lacking CT-1. Conclusions: Normotensive rats subjected to CT-1 overloading developed impaired cardiac and vascular functions, characterized by an increment in arterial stiffness accompanied by an augmented media thickness and extracellular matrix production. Accordingly, CT-1-null mice presented a reduced arterial stiffness and a reduced media thickness and collagen content. Our data show that CT-1 is a key player in arterial thickness and stiffness and in the cardiovascular coupling.","internal_url":"https://www.academia.edu/14031704/PREDICTIVE_VALUE_OF_CENTRAL_SYSTOLIC_AND_DIASTOLIC_PRESSURE_IN_CORONARY_PATIENTS_RESULTS_FROM_THE_AORTIC_BLOOD_PRESSURE_AND_SURVIVAL_STUDY_3A_04","translated_internal_url":"","created_at":"2015-07-14T06:56:26.742-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":33059564,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3118053,"work_id":14031704,"tagging_user_id":33059564,"tagged_user_id":33097976,"co_author_invite_id":787306,"email":"p***i@interia.pl","affiliation":"Jagiellonian University in Krakow","display_order":0,"name":"P. Jankowski","title":"PREDICTIVE VALUE OF CENTRAL SYSTOLIC AND DIASTOLIC PRESSURE IN CORONARY PATIENTS. RESULTS FROM THE AORTIC BLOOD PRESSURE AND SURVIVAL STUDY: 3A.04"},{"id":3118057,"work_id":14031704,"tagging_user_id":33059564,"tagged_user_id":null,"co_author_invite_id":787307,"email":"m***k@cyf-kr.edu.pl","display_order":4194304,"name":"K. Kawecka-jaszcz","title":"PREDICTIVE VALUE OF CENTRAL SYSTOLIC AND DIASTOLIC PRESSURE IN CORONARY PATIENTS. RESULTS FROM THE AORTIC BLOOD PRESSURE AND SURVIVAL STUDY: 3A.04"}],"downloadable_attachments":[],"slug":"PREDICTIVE_VALUE_OF_CENTRAL_SYSTOLIC_AND_DIASTOLIC_PRESSURE_IN_CORONARY_PATIENTS_RESULTS_FROM_THE_AORTIC_BLOOD_PRESSURE_AND_SURVIVAL_STUDY_3A_04","translated_slug":"","page_count":null,"language":"en","content_type":"Work","summary":"ABSTRACT Background and Aims: Besides its known cardiac effects, cardiotrophin-1 (CT-1), a cytokine belonging to the interleukin-6 family, exerts proliferative and secretory effects in vascular smooth muscle cells. We aimed to investigate the functional and morphological vascular changes induced by chronic CT-1 administration in rats and its involvement in the arterial phenotype of CT-1-null mice in vivo. Methods: A) Recombinant rat CT-1 (20 μg/Kg, IP) was administrated to Wistar rats for six weeks (n = 10/group). Blood pressure (BP) and heart rate were recorded by telemetry. Cardiac function was assessed using PET-scan. B) 2 year-old wild-type (WT) (n = 8) and CT-1-null mice (n = 3) were studied. Vascular structure and function were evaluated by an echo-tracking device. Circumferential wall stress, incremental elastic modulus (Einc), media cross-sectional area and pulse wave velocity (PWV) were measured. Aortic wall collagen and elastin contents were determined using immunohistochemistry, and the expression of collagen type I and III, elastin and fibronectin was quantified by RT-PCR and Western blot in aortic extracts. Results: A) Neither vehicle nor CT-1 treatment modified BP. CT-1-treated rats displayed decreased cardiac output (p \u0026amp;lt; 0.01) as well as wall stress (p \u0026amp;lt; 0.01), Einc (p \u0026amp;lt; 0.01) and PWV (p \u0026amp;lt; 0.05) as compared with vehicle group. CT-1-treated rats also showed increased media cross sectional area (p \u0026amp;lt; 0.01) and collagen content (p \u0026amp;lt; 0.01). CT-1-overloaded rats displayed increased expression of collagen type I (p \u0026amp;lt; 0.05) and III (p \u0026amp;lt; 0.01) and fibronectin (p \u0026amp;lt; 0.01). B) CT-1-null mice presented an increased wall stress (p \u0026amp;lt; 0.05) and Einc (p \u0026amp;lt; 0.05) as compared with WT mice. Media cross sectional area and collagen content were reduced (p \u0026amp;lt; 0.05) in mice lacking CT-1. Conclusions: Normotensive rats subjected to CT-1 overloading developed impaired cardiac and vascular functions, characterized by an increment in arterial stiffness accompanied by an augmented media thickness and extracellular matrix production. Accordingly, CT-1-null mice presented a reduced arterial stiffness and a reduced media thickness and collagen content. Our data show that CT-1 is a key player in arterial thickness and stiffness and in the cardiovascular coupling.","owner":{"id":33059564,"first_name":"Jerzy","middle_initials":null,"last_name":"Wiliński","page_name":"JerzyWiliński","domain_name":"independent","created_at":"2015-07-14T06:56:00.224-07:00","display_name":"Jerzy Wiliński","url":"https://independent.academia.edu/JerzyWili%C5%84ski"},"attachments":[],"research_interests":[{"id":71399,"name":"Hypertension","url":"https://www.academia.edu/Documents/in/Hypertension"},{"id":88321,"name":"Blood Pressure","url":"https://www.academia.edu/Documents/in/Blood_Pressure"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-14031704-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="14031702"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14031702/Pulsatile_but_Not_Steady_Component_of_Blood_Pressure_Predicts_Cardiovascular_Events_in_Coronary_Patients"><img alt="Research paper thumbnail of Pulsatile but Not Steady Component of Blood Pressure Predicts Cardiovascular Events in Coronary Patients" class="work-thumbnail" src="https://attachments.academia-assets.com/44684977/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14031702/Pulsatile_but_Not_Steady_Component_of_Blood_Pressure_Predicts_Cardiovascular_Events_in_Coronary_Patients">Pulsatile but Not Steady Component of Blood Pressure Predicts Cardiovascular Events in Coronary Patients</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/JerzyWili%C5%84ski">Jerzy Wiliński</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a></span></div><div class="wp-workCard_item"><span>Hypertension</span><span>, 2008</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Although the differences between central and peripheral blood pressure (BP) values have been know...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Although the differences between central and peripheral blood pressure (BP) values have been known for decades, the consequences of decision making based on peripheral rather than central BP have only recently been recognized. There are only a few studies assessing the relationship between intraaortic BP and cardiovascular risk. In addition, the relationship between central BP and the risk of cardiovascular events in a large group of coronary patients has not yet been evaluated. Therefore, the aim of the study was to determine the prognostic significance of central BP-derived indices in patients undergoing coronary angiography. Invasive central BPs were taken at baseline, and study end points were ascertained during over a 4.5-year follow-up in 1109 consecutive patients. The primary end point (cardiovascular death or myocardial infarction or stroke or cardiac arrest or heart transplantation or myocardial revascularization) occurred in 246 (22.2%) patients. Central pulsatility was the most powerful predictor of the primary end point (hazard ratio [HR] 1.30, 95% confidence interval [CI] 1.14 to 1.48). Central pulse pressure was also independently related to the primary end point (HR 1.25, 95% CI 1.09 to 1.43). Central mean BP as well as peripheral BP parameters were not independently related to the primary end point risk. Central pulsatility was also related to risk of cardiovascular death or myocardial infarction or stroke. The pulsatile component of BP is the most important factor related to the cardiovascular risk in coronary patients. It is more closely associated with cardiovascular risk than steady component of BP. (Hypertension. 2008;51:848-855.) Key Words: blood pressure Ⅲ central pulse pressure Ⅲ pulsatility Ⅲ cardiovascular risk Ⅲ atherosclerosis Ⅲ coronary artery disease</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="9a9b86b8fb011aef8962dbcf66a45efe" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44684977,"asset_id":14031702,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44684977/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14031702"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14031702"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14031702; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14031702]").text(description); $(".js-view-count[data-work-id=14031702]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14031702; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14031702']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "9a9b86b8fb011aef8962dbcf66a45efe" } } $('.js-work-strip[data-work-id=14031702]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14031702,"title":"Pulsatile but Not Steady Component of Blood Pressure Predicts Cardiovascular Events in Coronary Patients","translated_title":"","metadata":{"ai_title_tag":"Central Pulsatility Predicts Cardiovascular Events","grobid_abstract":"Although the differences between central and peripheral blood pressure (BP) values have been known for decades, the consequences of decision making based on peripheral rather than central BP have only recently been recognized. There are only a few studies assessing the relationship between intraaortic BP and cardiovascular risk. In addition, the relationship between central BP and the risk of cardiovascular events in a large group of coronary patients has not yet been evaluated. Therefore, the aim of the study was to determine the prognostic significance of central BP-derived indices in patients undergoing coronary angiography. Invasive central BPs were taken at baseline, and study end points were ascertained during over a 4.5-year follow-up in 1109 consecutive patients. The primary end point (cardiovascular death or myocardial infarction or stroke or cardiac arrest or heart transplantation or myocardial revascularization) occurred in 246 (22.2%) patients. Central pulsatility was the most powerful predictor of the primary end point (hazard ratio [HR] 1.30, 95% confidence interval [CI] 1.14 to 1.48). Central pulse pressure was also independently related to the primary end point (HR 1.25, 95% CI 1.09 to 1.43). Central mean BP as well as peripheral BP parameters were not independently related to the primary end point risk. Central pulsatility was also related to risk of cardiovascular death or myocardial infarction or stroke. The pulsatile component of BP is the most important factor related to the cardiovascular risk in coronary patients. It is more closely associated with cardiovascular risk than steady component of BP. (Hypertension. 2008;51:848-855.) Key Words: blood pressure Ⅲ central pulse pressure Ⅲ pulsatility Ⅲ cardiovascular risk Ⅲ atherosclerosis Ⅲ coronary artery disease","publication_date":{"day":null,"month":null,"year":2008,"errors":{}},"publication_name":"Hypertension","grobid_abstract_attachment_id":44684977},"translated_abstract":null,"internal_url":"https://www.academia.edu/14031702/Pulsatile_but_Not_Steady_Component_of_Blood_Pressure_Predicts_Cardiovascular_Events_in_Coronary_Patients","translated_internal_url":"","created_at":"2015-07-14T06:56:26.654-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":33059564,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3118051,"work_id":14031702,"tagging_user_id":33059564,"tagged_user_id":140578231,"co_author_invite_id":330611,"email":"m***k@cyf-kr.edu.pl","display_order":0,"name":"Dariuz Dudek","title":"Pulsatile but Not Steady Component of Blood Pressure Predicts Cardiovascular Events in Coronary Patients"},{"id":3118052,"work_id":14031702,"tagging_user_id":33059564,"tagged_user_id":33097976,"co_author_invite_id":787306,"email":"p***i@interia.pl","affiliation":"Jagiellonian University in Krakow","display_order":4194304,"name":"P. 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There are only a few studies assessing the relationship between intraaortic BP and cardiovascular risk. In addition, the relationship between central BP and the risk of cardiovascular events in a large group of coronary patients has not yet been evaluated. Therefore, the aim of the study was to determine the prognostic significance of central BP-derived indices in patients undergoing coronary angiography. Invasive central BPs were taken at baseline, and study end points were ascertained during over a 4.5-year follow-up in 1109 consecutive patients. The primary end point (cardiovascular death or myocardial infarction or stroke or cardiac arrest or heart transplantation or myocardial revascularization) occurred in 246 (22.2%) patients. Central pulsatility was the most powerful predictor of the primary end point (hazard ratio [HR] 1.30, 95% confidence interval [CI] 1.14 to 1.48). Central pulse pressure was also independently related to the primary end point (HR 1.25, 95% CI 1.09 to 1.43). Central mean BP as well as peripheral BP parameters were not independently related to the primary end point risk. Central pulsatility was also related to risk of cardiovascular death or myocardial infarction or stroke. The pulsatile component of BP is the most important factor related to the cardiovascular risk in coronary patients. It is more closely associated with cardiovascular risk than steady component of BP. (Hypertension. 2008;51:848-855.) Key Words: blood pressure Ⅲ central pulse pressure Ⅲ pulsatility Ⅲ cardiovascular risk Ⅲ atherosclerosis Ⅲ coronary artery disease","owner":{"id":33059564,"first_name":"Jerzy","middle_initials":null,"last_name":"Wiliński","page_name":"JerzyWiliński","domain_name":"independent","created_at":"2015-07-14T06:56:00.224-07:00","display_name":"Jerzy Wiliński","url":"https://independent.academia.edu/JerzyWili%C5%84ski"},"attachments":[{"id":44684977,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/44684977/thumbnails/1.jpg","file_name":"848.pdf","download_url":"https://www.academia.edu/attachments/44684977/download_file","bulk_download_file_name":"Pulsatile_but_Not_Steady_Component_of_Bl.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/44684977/848-libre.pdf?1460530395=\u0026response-content-disposition=attachment%3B+filename%3DPulsatile_but_Not_Steady_Component_of_Bl.pdf\u0026Expires=1743675859\u0026Signature=dXQ5-FQlVi8avbGw5HKiJKe9x5gVWGpB3pLSiWbZ~1MGOuCvNzYGNrE2O6zvcMokKKIJQJqrAIvEuOl3IzN2SAuD0xrYmoKpjZWOcbUn45wdNqdj~ZZ-Ud9R2TcCfCT3IiTh22RckiEtgk7ApNbv6RorJ9iBZqNLl5j1mHRqS2GqcXv8LiOjuVFAqe-uAoiy1Gawx57~HFIGyGLjhknVEScrbkhBRKlY1CvIY7JRBrG4gZV-YM2TByvSsaSDjEUwqVpvsi1zqCenMBGKf0cpMc0Idb3qmdsX7bz9X-rs6-V9bCGwST2QqqGucHcd-9eXZW05OB0EKJJ4G1r0w3CZVg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":1681,"name":"Decision Making","url":"https://www.academia.edu/Documents/in/Decision_Making"},{"id":29154,"name":"Cardiovascular Risk","url":"https://www.academia.edu/Documents/in/Cardiovascular_Risk"},{"id":61235,"name":"Cardiac arrest","url":"https://www.academia.edu/Documents/in/Cardiac_arrest"},{"id":71399,"name":"Hypertension","url":"https://www.academia.edu/Documents/in/Hypertension"},{"id":88321,"name":"Blood Pressure","url":"https://www.academia.edu/Documents/in/Blood_Pressure"},{"id":167876,"name":"Myocardial Revascularization","url":"https://www.academia.edu/Documents/in/Myocardial_Revascularization"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":374984,"name":"Coronary Angiography","url":"https://www.academia.edu/Documents/in/Coronary_Angiography"},{"id":401305,"name":"Betweenness Centrality","url":"https://www.academia.edu/Documents/in/Betweenness_Centrality"},{"id":489727,"name":"Prognosis","url":"https://www.academia.edu/Documents/in/Prognosis"},{"id":497321,"name":"Pulse Pressure","url":"https://www.academia.edu/Documents/in/Pulse_Pressure"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1"},{"id":789977,"name":"Coronary Artery Disease","url":"https://www.academia.edu/Documents/in/Coronary_Artery_Disease"},{"id":987931,"name":"Heart Transplantation","url":"https://www.academia.edu/Documents/in/Heart_Transplantation"},{"id":1035092,"name":"Aorta","url":"https://www.academia.edu/Documents/in/Aorta"},{"id":1272981,"name":"Proportional Hazards Models","url":"https://www.academia.edu/Documents/in/Proportional_Hazards_Models"},{"id":1318932,"name":"Predictive value of tests","url":"https://www.academia.edu/Documents/in/Predictive_value_of_tests"},{"id":1434623,"name":"Pulsatile Flow","url":"https://www.academia.edu/Documents/in/Pulsatile_Flow"},{"id":1587858,"name":"Confidence Interval","url":"https://www.academia.edu/Documents/in/Confidence_Interval"},{"id":2256667,"name":"Brachial artery","url":"https://www.academia.edu/Documents/in/Brachial_artery"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-14031702-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="14087542"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/14087542/AT_HIGH_SALT_INTAKE_CAROTID_INTIMA_MEDIA_THICKNESS_INCREASES_WITH_CENTRAL_PULSE_PRESSURE_A_POPULATION_STUDY_PP_10_400"><img alt="Research paper thumbnail of AT HIGH SALT INTAKE CAROTID INTIMA-MEDIA THICKNESS INCREASES WITH CENTRAL PULSE PRESSURE: A POPULATION STUDY: PP.10.400" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title">AT HIGH SALT INTAKE CAROTID INTIMA-MEDIA THICKNESS INCREASES WITH CENTRAL PULSE PRESSURE: A POPULATION STUDY: PP.10.400</div><div class="wp-workCard_item"><span>Journal of Hypertension</span><span>, 2010</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14087542"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14087542"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14087542; 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Jankowski","url":"https://uj-pl.academia.edu/PJankowski"},"attachments":[],"research_interests":[{"id":71399,"name":"Hypertension","url":"https://www.academia.edu/Documents/in/Hypertension"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":497321,"name":"Pulse Pressure","url":"https://www.academia.edu/Documents/in/Pulse_Pressure"},{"id":634767,"name":"The Carotid Artery Intima Media Thickness","url":"https://www.academia.edu/Documents/in/The_Carotid_Artery_Intima_Media_Thickness"},{"id":718203,"name":"Population Study","url":"https://www.academia.edu/Documents/in/Population_Study"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") if (false) { Aedu.setUpFigureCarousel('profile-work-14087542-figures'); } }); </script> <div class="js-work-strip profile--work_container" data-work-id="14087541"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/14087541/Ascending_aortic_blood_pressure_waveform_may_be_related_to_the_risk_of_coronary_artery_disease_in_women_but_not_in_men"><img alt="Research paper thumbnail of Ascending aortic blood pressure waveform may be related to the risk of coronary artery disease in women, but not in men" class="work-thumbnail" src="https://attachments.academia-assets.com/44617930/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14087541/Ascending_aortic_blood_pressure_waveform_may_be_related_to_the_risk_of_coronary_artery_disease_in_women_but_not_in_men">Ascending aortic blood pressure waveform may be related to the risk of coronary artery disease in women, but not in men</a></div><div class="wp-workCard_item"><span>Journal of Human Hypertension</span><span>, 2004</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Recent studies have demonstrated that fractional pulse pressure and fractional diastolic pressure...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Recent studies have demonstrated that fractional pulse pressure and fractional diastolic pressure are related to the risk of coronary artery disease. However, the effect of the ascending aortic pressure waveform on the risk of coronary artery disease in men and women analyzed separately has not been reported. The objective of the study was to assess the relation between ascending aortic blood pressure waveform and the presence of coronary artery disease in men and in women. The study group consisted of 447 patients (302 men and 145 women; mean age: 57.679.8 years) with preserved left ventricular function who were undergoing first diagnostic coronary angiography. After multivariate stepwise adjustments, the odds ratio (OR) and confidence interval (CI) of having coronary artery disease in women was (OR are reported for standard deviation increase in each variable): pulse pressure OR 1.61 (95% CI 1.06-2.46); fractional systolic pressure OR 1.72 (95% CI 1.08-2.71); fractional diastolic pressure OR 0.58 (95% CI 0.37-0.92); fractional pulse pressure OR 1.72 (95% CI 1.08-2.71); and pulsatility index OR 1.74 (95% CI 1.09-2.78). None of the studied variables was independently related to the presence of coronary artery disease in men. In conclusion, fractional systolic and diastolic pressure, pulse pressure, fractional pulse pressure and the ratio of pulse pressure to diastolic pressure may be independently related to the risk of coronary artery disease in women, but not in men.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="32f4a8caf2aba3a3036c217cd5c45287" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44617930,"asset_id":14087541,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44617930/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14087541"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14087541"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14087541; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14087541]").text(description); $(".js-view-count[data-work-id=14087541]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14087541; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14087541']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "32f4a8caf2aba3a3036c217cd5c45287" } } $('.js-work-strip[data-work-id=14087541]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14087541,"title":"Ascending aortic blood pressure waveform may be related to the risk of coronary artery disease in women, but not in men","translated_title":"","metadata":{"grobid_abstract":"Recent studies have demonstrated that fractional pulse pressure and fractional diastolic pressure are related to the risk of coronary artery disease. However, the effect of the ascending aortic pressure waveform on the risk of coronary artery disease in men and women analyzed separately has not been reported. The objective of the study was to assess the relation between ascending aortic blood pressure waveform and the presence of coronary artery disease in men and in women. The study group consisted of 447 patients (302 men and 145 women; mean age: 57.679.8 years) with preserved left ventricular function who were undergoing first diagnostic coronary angiography. After multivariate stepwise adjustments, the odds ratio (OR) and confidence interval (CI) of having coronary artery disease in women was (OR are reported for standard deviation increase in each variable): pulse pressure OR 1.61 (95% CI 1.06-2.46); fractional systolic pressure OR 1.72 (95% CI 1.08-2.71); fractional diastolic pressure OR 0.58 (95% CI 0.37-0.92); fractional pulse pressure OR 1.72 (95% CI 1.08-2.71); and pulsatility index OR 1.74 (95% CI 1.09-2.78). None of the studied variables was independently related to the presence of coronary artery disease in men. 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However, the effect of the ascending aortic pressure waveform on the risk of coronary artery disease in men and women analyzed separately has not been reported. The objective of the study was to assess the relation between ascending aortic blood pressure waveform and the presence of coronary artery disease in men and in women. The study group consisted of 447 patients (302 men and 145 women; mean age: 57.679.8 years) with preserved left ventricular function who were undergoing first diagnostic coronary angiography. After multivariate stepwise adjustments, the odds ratio (OR) and confidence interval (CI) of having coronary artery disease in women was (OR are reported for standard deviation increase in each variable): pulse pressure OR 1.61 (95% CI 1.06-2.46); fractional systolic pressure OR 1.72 (95% CI 1.08-2.71); fractional diastolic pressure OR 0.58 (95% CI 0.37-0.92); fractional pulse pressure OR 1.72 (95% CI 1.08-2.71); and pulsatility index OR 1.74 (95% CI 1.09-2.78). None of the studied variables was independently related to the presence of coronary artery disease in men. In conclusion, fractional systolic and diastolic pressure, pulse pressure, fractional pulse pressure and the ratio of pulse pressure to diastolic pressure may be independently related to the risk of coronary artery disease in women, but not in men.","owner":{"id":33097976,"first_name":"P.","middle_initials":null,"last_name":"Jankowski","page_name":"PJankowski","domain_name":"uj-pl","created_at":"2015-07-15T14:10:55.720-07:00","display_name":"P. 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Jankowski</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/JacekDragan">Jacek Dragan</a></span></div><div class="wp-workCard_item"><span>American journal of …</span><span>, 2004</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Ascending aortic fractional pulse pressure and fractional systolic pressure (FSP) were demonstrat...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Ascending aortic fractional pulse pressure and fractional systolic pressure (FSP) were demonstrated to differentiate patients with and without coronary artery disease. However, no study so far has analyzed the relationship between FSP and fractional diastolic pressure (FDP) and the ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="a2e0f9a033767bf2eebf1edfd3fce142" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44617919,"asset_id":14087540,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44617919/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14087540"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14087540"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14087540; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14087540]").text(description); $(".js-view-count[data-work-id=14087540]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14087540; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14087540']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "a2e0f9a033767bf2eebf1edfd3fce142" } } $('.js-work-strip[data-work-id=14087540]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14087540,"title":"Fractional diastolic and systolic pressure in the ascending aorta are related to the extent of coronary artery disease","translated_title":"","metadata":{"abstract":"Ascending aortic fractional pulse pressure and fractional systolic pressure (FSP) were demonstrated to differentiate patients with and without coronary artery disease. 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Do the potential benefits of pulmonary artery angiography support the decision to perform the procedure?" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title">Acute pulmonary embolism mimicking STEMI. Do the potential benefits of pulmonary artery angiography support the decision to perform the procedure?</div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://uj-pl.academia.edu/PJankowski">P. Jankowski</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/JerzyWili%C5%84ski">Jerzy Wiliński</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/MarekRajzer">Marek Rajzer</a></span></div><div class="wp-workCard_item"><span>Przegla̧d lekarski</span><span>, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">This case report concerns a 68 year old male with, type 2 diabetes, stage 3 hypertension, hyperch...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">This case report concerns a 68 year old male with, type 2 diabetes, stage 3 hypertension, hypercholesterolemia, myocardial infarction (MI) 20 years ago. He was admitted to the catheterization laboratory with suspected acute inferior wall MI. Angiography of pulmonary arteries revealed massive thrombosis.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14031709"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14031709"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14031709; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14031709]").text(description); $(".js-view-count[data-work-id=14031709]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14031709; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14031709']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=14031709]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14031709,"title":"Acute pulmonary embolism mimicking STEMI. 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Angiography of pulmonary arteries revealed massive thrombosis.","internal_url":"https://www.academia.edu/14031709/Acute_pulmonary_embolism_mimicking_STEMI_Do_the_potential_benefits_of_pulmonary_artery_angiography_support_the_decision_to_perform_the_procedure","translated_internal_url":"","created_at":"2015-07-14T06:56:27.029-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":33059564,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3118054,"work_id":14031709,"tagging_user_id":33059564,"tagged_user_id":33097976,"co_author_invite_id":787306,"email":"p***i@interia.pl","affiliation":"Jagiellonian University in Krakow","display_order":0,"name":"P. Jankowski","title":"Acute pulmonary embolism mimicking STEMI. Do the potential benefits of pulmonary artery angiography support the decision to perform the procedure?"},{"id":3118059,"work_id":14031709,"tagging_user_id":33059564,"tagged_user_id":34036833,"co_author_invite_id":787309,"email":"r***7@interia.pl","display_order":4194304,"name":"Marek Rajzer","title":"Acute pulmonary embolism mimicking STEMI. Do the potential benefits of pulmonary artery angiography support the decision to perform the procedure?"}],"downloadable_attachments":[],"slug":"Acute_pulmonary_embolism_mimicking_STEMI_Do_the_potential_benefits_of_pulmonary_artery_angiography_support_the_decision_to_perform_the_procedure","translated_slug":"","page_count":null,"language":"en","content_type":"Work","summary":"This case report concerns a 68 year old male with, type 2 diabetes, stage 3 hypertension, hypercholesterolemia, myocardial infarction (MI) 20 years ago. He was admitted to the catheterization laboratory with suspected acute inferior wall MI. Angiography of pulmonary arteries revealed massive thrombosis.","owner":{"id":33059564,"first_name":"Jerzy","middle_initials":null,"last_name":"Wiliński","page_name":"JerzyWiliński","domain_name":"independent","created_at":"2015-07-14T06:56:00.224-07:00","display_name":"Jerzy Wiliński","url":"https://independent.academia.edu/JerzyWili%C5%84ski"},"attachments":[],"research_interests":[{"id":71399,"name":"Hypertension","url":"https://www.academia.edu/Documents/in/Hypertension"},{"id":102587,"name":"Pulmonary Embolism","url":"https://www.academia.edu/Documents/in/Pulmonary_Embolism"},{"id":130343,"name":"Hypercholesterolemia","url":"https://www.academia.edu/Documents/in/Hypercholesterolemia"},{"id":162159,"name":"Differential Diagnosis","url":"https://www.academia.edu/Documents/in/Differential_Diagnosis"},{"id":247701,"name":"Angiography","url":"https://www.academia.edu/Documents/in/Angiography"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged"},{"id":378016,"name":"Myocardial Infarction","url":"https://www.academia.edu/Documents/in/Myocardial_Infarction"},{"id":915951,"name":"Type 2 Diabetes Mellitus","url":"https://www.academia.edu/Documents/in/Type_2_Diabetes_Mellitus"},{"id":2369445,"name":"Pulmonary Artery","url":"https://www.academia.edu/Documents/in/Pulmonary_Artery"}],"urls":[]}, dispatcherData: dispatcherData }); 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