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Finding Early Alzheimer’s - Exel: Drexel University's Research Magazine
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class="issue issue-middle" id="issue-2023"> <div class="issue-image"></div> <h3 class="issue-title">Exel 2023</h3> </a> <!-- end issue --> </div> </div> <!-- end nav dropdown --> </li> <!-- end nav contents --> <li><a href="/issues/">Archives</a></li> </ul> <div class="quick-search-container"> <form id="qsearchform" method="get" action="https://exelmagazine.org/" style="margin: 0; padding: 0;"> <input id="quick-search" name="s" placeholder="Search" type="text" /> <span class="quick-search-icon icon-thin-search" onclick="jQuery('#qsearchform').submit();"></span> </form> </div> </nav> </div> </div> </header> <!-- end header --> <div id="top-pad"> </div> <div class="white-section story-section article-news"> <div class="exel-x"> <div class="exel-x-image"> </div> <h3>2023<br/><span class="article-department">_MEDICINE</span> Artificial Intelligence</h3> </div> <div class="row-fluid news-header"> <h2 class="news-title">_Finding Early Alzheimer’s</h2><div class="news-excerpt">The natural language AI algorithms behind the chatbot program ChatGPT can help doctors spot early Alzheimer’s disease, researchers find. <span class="article-byline"></span></div> </div> <!-- Main Section --> <div class="row-fluid row-main"> <div class="article-content"> <div class="article-researcher"><div class="article-researcher-image"><img src="https://960cca.a2cdn1.secureserver.net/wp-content/uploads/2023/06/Liang-Haulou.png?time=1732092036" alt="" /></div><h3>_Hualou Liang</h3><p>Liang is a professor of biomedical engineering in the School of Biomedical Engineering, Science & Health Systems.</p></div><div class="article-researcher"><div class="article-researcher-image"><img src="https://960cca.a2cdn1.secureserver.net/wp-content/uploads/2023/06/Felix-Agbavor.png?time=1732092036" alt="" /></div><h3>_Felix Agbavor</h3><p>Agbavor, a doctoral student, collaborated on the research. </p></div> <div class="article-content-inner"> <p>A team from Drexel’s School of Biomedical Engineering, Science and Health Systems has used a popular chatbot program to identify clues from spontaneous speech that <a href="https://drexel.edu/news/archive/2022/December/GPT-3-alzheimers-disease">predict early stages of dementia</a>, with 80% accuracy.</p> <p>The team’s work, reported in the journal <em><a href="https://journals.plos.org/digitalhealth/article?id=10.1371/journal.pdig.0000168">PLOS Digital Health</a></em>, is the latest in a series of efforts to show the effectiveness of natural language processing programs in spotting speech delays and other verbal tics that are indicative of neurodegenerative disorders. </p> <p>The researchers tested their theory by training OpenAI’s GPT-3 with recorded speech transcripts from people exhibiting varying stages of Alzheimer’s decline. From that, GPT-3 generated a characteristic profile of Alzheimer’s speech. That was then used to retrain the program — turning it into an Alzheimer’s disease screening machine. </p> <blockquote><p> <img decoding="async" src="https://960cca.a2cdn1.secureserver.net/wp-content/uploads/2023/06/EXEL2023_Web_sidebars_FindingEarlyAlzeimers.jpg" /></p> <h3> </h3> <h4> </h4> </blockquote> <p>The process was demonstrated to reliably predict those who have Alzheimer’s disease and those who don’t.</p> <p>The team also found that GPT-3 was 20% more accurate in predicting the severity of disease than an alternative analysis based solely on the acoustic features of the recordings, such as pauses, voice strength and slurring.</p> <p>The team’s findings could speed Alzheimer’s diagnosis, currently a lengthy process that involves a medical history review and a host of physical and neurological tests. Spotting the disease early would give patients more options for therapeutics and support. </p> <p>To build on these promising results, the researchers are planning to develop a pre-screening tool that could be used at home or in a doctor’s office.</p> <div class="social-button-container"> <a target="_blank" href="http://www.facebook.com/sharer.php?u=https://exelmagazine.org/article/finding-early-alzheimers/&t=Finding Early Alzheimer’s"><span class="icon icon-facebook-sign"></span></a> <a target="_blank" href="http://twitter.com/home?status=Currently%20reading%3A%20%40DrexelUniv%27s%20EXEL%20Magazine%20https%3A%2F%2Fexelmagazine.org%2Farticle%2Ffinding-early-alzheimers%2F" title="Click to share this post on Twitter"><span class="icon icon-twitter-sign"></span></a> </div> </div> </div> </div> <!-- end row --> </div> <script type="text/javascript">;(function(window, document, undefined, $) {$(document).ready(function(){ $('h6').fitText('.3');$(".article-content-inner p:nth-child(1)").initialLetter({ initialLetter: "dropped" });var exel_paras = 1; $(".article-content-inner p").each(function(){ $(this).addClass("article-paragraph-" + exel_paras); exel_paras = exel_paras + 1; });var exel_attachments = []; var i = ""; for (x in exel_attachments){ if (exel_attachments[x]["post_title"].toLowerCase()=="none"){ i = '<div class="article-main-image"><img src="'+exel_attachments[x]["large_image"][0] + '" /></div>'; } else { i = '<div class="article-main-image"><img src="'+exel_attachments[x]["large_image"][0] + '" /><div class="article-main-image-content"><h3>' + exel_attachments[x]["post_title"] + '</h3><p>' + exel_attachments[x]["post_content"] + '</p></div></div>'; } switch(x){ case "1": $(".article-paragraph-3").after(i); break; case "2": $(".article-paragraph-6").after(i); break; case "3": $(".article-paragraph-9").after(i); break; case "4": $(".article-paragraph-12").after(i); break; case "5": $(".article-paragraph-15").after(i); break; case "6": $(".article-paragraph-19").after(i); break; case "7": $(".article-paragraph-22").after(i); break; case "8": $(".article-paragraph-25").after(i); break; case "9": $(".article-paragraph-30").after(i); break; }; }$(".article-main-image").fadeIn("slow");});})(window, document, undefined, jQuery);</script> </div> <footer> <div class="row-fluid row-footer"> <div class="span3 footer-identity-container"> <img src="/wp-content/themes/exel/a/i/drexel-logo-white.png?v=32" alt="Drexel University" id="footer-identity"> </div> <div class="span3"> <dl> <dt>Drexel University</dt> <dd>3141 Chestnut Street</dd> <dd>Philadelphia, PA 19104</dd> <dd>215-895-2000</dd> <dd>© Copyright 2023 All Rights Reserved.</dd> </dl> </div> <div class="span3"> <dl> <dt>Quick Links</dt> <dd><a href="http://www.drexel.edu">Drexel Homepage</a></dd> <dd><a href="http://www.drexel.edu/research/">Drexel Research & Innovation</a></dd> <dd><a href="http://www.drexel.edu/academics/schools/">Drexel Colleges & Schools</a></dd> <dd><a href="http://drexel.edu/provost/">Drexel Office of the Provost</a></dd> </dl> </div> <div class="span2 exel-links"> <dl> <dt>Exel Magazine</dt> <dd><a href="/about/">About</a></dd> <dd><a href="https://drexel.edu/privacy">Privacy Policy</a></dd> <dd><a href="/letter/">Letter from President</a></dd> <dd><a href="/contact/">Contact</a></dd> </dl> </div> </div> </footer> <!-- <link rel="stylesheet" href="/wp-content/themes/exel/a/css/royalslider.css" type="text/css" media="all"> <link rel="stylesheet" href="/wp-content/themes/exel/a/css/rs-default.css" type="text/css" media="all"> --> <!-- HFCM by 99 Robots - Snippet # 2: GTM - body --> <!-- Google Tag Manager --> <noscript><iframe src="//www.googletagmanager.com/ns.html?id=GTM-TJCKC2" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript> <!-- End Google Tag Manager --> <!-- /end HFCM by 99 Robots --> <script type="text/javascript"> (function(i,s,o,g,r,a,m){i['GoogleAnalyticsObject']=r;i[r]=i[r]||function(){ (i[r].q=i[r].q||[]).push(arguments)},i[r].l=1*new Date();a=s.createElement(o), m=s.getElementsByTagName(o)[0];a.async=1;a.src=g;m.parentNode.insertBefore(a,m) })(window,document,'script','//www.google-analytics.com/analytics.js','ga'); ga('create', 'UA-33235850-1', 'auto'); ga('send', 'pageview'); </script> </body> </html>