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(PDF) European Experience on the Practical Use of Levosimendan in Patients with Acute Heart Failure Syndromes | Ferenc Follath - Academia.edu

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Recent reports on clinical experience confirm the positive hemodynamic results and beneficial clinical effects described in the initial dose-finding and randomized comparative therapeutic trials in patients with severe low-output heart failure. In addition, studies in small series of patients with cardiogenic shock after myocardial infarction and/or surgical interventions and postinterventional myocardial dysfunction stunning) indicate that the inotropic and vasodilating actions of levosimendan may be of value in a wider range of indications. Dose recommendations, combination with other drugs, and potential side effects are discussed in this overview. © 2005 Elsevier Inc. All rights reserved. (Am J Cardiol 2005;96[suppl]:80G-85G)","publication_date":"2005,,","publication_name":"The American Journal of Cardiology","grobid_abstract_attachment_id":"49566530"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"European Experience on the Practical Use of Levosimendan in Patients with Acute Heart Failure Syndromes","broadcastable":true,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [54773906]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "control"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container 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data-author-id="15140206" href="https://independent.academia.edu/WilliamSmith50">William Smith</a></div><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Acute Hemodynamic and Clinical Effects of Levosimendan in Patients With Severe Heart Failure&quot;,&quot;attachmentId&quot;:34425787,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/7951441/Acute_Hemodynamic_and_Clinical_Effects_of_Levosimendan_in_Patients_With_Severe_Heart_Failure&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/7951441/Acute_Hemodynamic_and_Clinical_Effects_of_Levosimendan_in_Patients_With_Severe_Heart_Failure"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="36160321" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/36160321/The_Role_of_Calcium_Sensitizer_Levosimendan_for_the_Treatment_of_Heart_Failure">The Role of Calcium-Sensitizer Levosimendan for the Treatment of Heart Failure</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="3594081" href="https://independent.academia.edu/sciepubcomSciEP">sciepub.com SciEP</a></div><p class="ds-related-work--abstract ds2-5-body-sm">In the treatment of heart failure, clinical signs are low cardiac output, therapy with positive inotropic agents in an acute cardiac care is mandatory. 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