CINXE.COM

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Cell Viability Flow Cytometry Protocol</h2> </a> <i>Protocols</i><br /> <p> Flow Cytometry Cell Viability Overview Flow cytometry is a quick and reliable method to quantify viable cells. Determining cell viability is an important step when evaluating a cells response to drug treatments or other environmental factors. It is also often necessary to distinguish dead cells in a cell suspension in order to exclude them from analysis. Dead cells can...</p> <a class="resources_link btn btn-tertiary" href="resources/protocols/flow-cytometry-protocol-analysis-cell-viability-using-propidium-iodide">More Info</a> </div> <div class="resources_element"> <a class="resources_title" href="resources/posters/concepts-mineral-homeostasis"> <h2>Concepts in Mineral Homeostasis</h2> </a> <i>Posters</i><br /> <p>Click for larger image. The importance of both Ca2+ and Pi in the body is reflected in the exquisite hormonal regulation associated with each element. Calcium (Ca2+) represents approximately 1-2% of total body weight, while phosphorus (Pi) constitutes approximately half that amount. Although most Ca2+ (99%) and Pi (85%) exist as a complex within bone, each has a number of critical non-structural...</p> <a class="resources_link btn btn-tertiary" href="resources/posters/concepts-mineral-homeostasis">More Info</a> </div> <div class="resources_element"> <a class="resources_title" href="resources/articles/akt-modulates-tgf-beta-activities"> <h2>Akt Modulates TGF-beta Activities</h2> </a> <i>Article</i><br /> <p>TGF-ß, the prototypical member of the TGF-ß superfamily, acts as a potent growth inhibitor or stimulator of apoptosis in many cell types. The downstream signaling initiated by TGF-ß binding to its serine/threonine kinase receptor is carried out by members of the Smad family. 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The PCa tumor microenvironment is comprised of a complex mixture of epithelial and stroma cell types engaged in multifaceted...</p> <a class="resources_link btn btn-tertiary" href="blog/understanding-immunosuppressive-myeloid-cells-and-immunotherapy-using-proteome-profiler">More Info</a> </div> <div class="resources_element"> <a class="resources_title" href="research-area/apoptosis-intracellular-kinases"> <h2>Apoptosis Intracellular Kinases</h2> </a> <i>Research Areas</i><br /> <p>Intracellular signaling pathways regulate the decision of whether a cell lives or dies. While death ligands such as Fas and TNF-alpha bind to their receptors to promote caspase activation and cell death, anti-apoptotic ligands, such as growth factors, bind to cell surface receptors and activate intracellular kinases that promote cell survival. These kinases include PI 3-K, Akt/PKB, PKA, PKC,...</p> <a class="resources_link btn btn-tertiary" href="research-area/apoptosis-intracellular-kinases">More Info</a> </div> <div class="resources_element"> <a class="resources_title" href="pathways/akt-signaling-pathway"> <h2>Akt Signaling Pathway</h2> </a> <i>Pathways</i><br /> <p>PI 3-Kinase can be activated by numerous stimuli, including mitogen-stimulated receptor tyrosine kinases (RTKs). The PI 3-Kinase p85 regulatory subunit interacts with RTKs either directly via its Src-homology 2 (SH2) domains or indirectly via an adaptor protein, such as GAB. Activated PI 3-Kinase then phosphorylates phosphatidylinositol (4,5)-bisphosphate (PIP2), resulting in the formation of...</p> <a class="resources_link btn btn-tertiary" href="pathways/akt-signaling-pathway">More Info</a> </div> <div class="resources_element"> <a class="resources_title" href="resources/technical/calcium-phosphorus-metabolism"> <h2>Calcium & Phosphorus Metabolism</h2> </a> <i>Article</i><br /> <p>First Published in R&D Systems' 2007 Catalog Contents Intestinal Absorption Calcium Phosphorus Serum Calcium & Phosphorus Molecules Regulating Calcium & Phosphorus Metabolism Renal Resporption of Calcium and Phosphorus Bone Formation and Resporption Elementary physiology and biochemistry texts generally do not have sections dedicated to inorganic elements or metals. 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