CINXE.COM

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class="cta-header-secondary-menu-investors popup-content" style="display:none; background:#fff;"> <h2 class="text-align-center">SIE WERDEN WEITERGELEITET</h2> <p class="text-align-center">Sie sind im Begriff, www.alnylam.at zu verlassen und zu unserer globalen Website (www.alnylam.com) zu gehen, die in englischer Sprache verfasst ist.</p> <p class="text-align-center"><a class="button-more text-center" href="https://investors.alnylam.com/">WEITER</a></p> </div> </div> <div class="popup-content" style="display:none; background:#fff; padding:opx;"> <div class="cta-header-secondary-menu-careers popup-content" style="display:none; background:#fff;"> <h2 class="text-align-center">SIE WERDEN WEITERGELEITET</h2> <p class="text-align-center">Sie sind im Begriff, www.alnylam.at zu verlassen und zu unserer globalen Website (www.alnylam.com) zu gehen, die in englischer Sprache verfasst ist.</p> <p class="text-align-center"><a class="button-more text-center" href="/careers/">WEITER</a></p> </div> </div> </div> </section> <section id="block-language-4" class="block block-block-content block-block-content5a7dc698-6efe-4c02-a3cd-adb2377d4faf clearfix"> <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><div class="language block" id="language-switcher-icon">language<i class="fas fa-angle-down"></i></div> </div> </section> </div> </div> </div> <div class="row ext-cta"> <div class="clp-header-right-bottom"> <div class="region region-clp-header-right-bottom"> <section id="block-clpheaderblockforswitzerlandgerman" class="block block-block-content block-block-contenta3e8a344-e62b-4ce2-9084-3a9961ec09ec clearfix"> <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><p><a data-colorbox-inline=".cta-header-switzerland-german">Besuchen Sie die globale Website von Alnylam (in englischer Sprache) ›</a></p> <div class="popup-content" style="display:none; background:#fff; padding:opx;"> <div class="cta-header-switzerland-german popup-content" style="display:none; background:#fff;"> <h2 class="text-align-center">SIE WERDEN WEITERGELEITET</h2> <p class="text-center text-align-center">Sie sind im Begriff, www.alnylam.ch zu verlassen und zu unserer globalen Website (www.alnylam.com) zu gehen, die in englischer Sprache verfasst ist.</p> <p class="text-align-center"><a class="button-more text-center" href="/">WEITER</a></p> </div> </div> </div> </section> </div> </div> </div> <div class="clp-language-switcher-block-wrapper"> <div class="clp-language-switcher-block"> <div class="region region-clp-header-language-block"> <section id="block-languageswitcherforclpswitzerlandgerman" class="block block-block-content block-block-contente64da26b-86e1-438b-bc95-f869ec8ab70f clearfix"> <div class="field field--name-field-language-link field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1087 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Global</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/">English</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1088 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Österreich</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-austria">Deutsch</a></div> </div> </span> </div> </div> </div> <div class="field--item"> 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class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Frankreich</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.fr/">Français</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1095 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Deutschland</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.de/">Deutsch</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1096 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Irland</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-ireland">English</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1097 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Italien</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.it/">Italiano</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1098 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Japan</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.jp/">Japanese</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1099 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Luxemburg</div> </span><span class="link-text"> <div class="field 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class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Portugal</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-portugal">Português</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1102 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Spanien</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-espana">Español</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1103 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Schweden</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-sverige">Svenska</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1104 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Schweiz</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-switzerland-french">Français</a></div> <div class="field--item"><a href="/alnylam-switzerland-german">Deutsch</a></div> <div class="field--item"><a href="/alnylam-switzerland-italian">Italiano</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1105 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Taiwan</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-taiwan">Traditional Chinese</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1106 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Königreich Großbritannien</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-uk">English</a></div> </div> </span> </div> </div> </div> </div> </section> </div> </div> </div> </div> </div> </div> </header> <div id="maindiv" class="container-fluid"> <main id="midcontent-area" class="column main-content"> <div id="content"> <div class="region region-content"> <div data-drupal-messages-fallback class="hidden"></div> <article data-history-node-id="688" role="article" about="/alnylam-switzerland-german" class="clp full clearfix"> <div class="content"> <div class="field field--name-field-add-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--banner-with-text paragraph-id--1312 paragraph--view-mode--default"> <div class="paragraph paragraph--type--banner-with-text paragraph-id--1312 paragraph--view-mode--default"> <div id="simple-banner-with-text-wrapper" style="background: url(/sites/default/files/2022-05/CLP_header_slider_hero_0.jpg); background-size: cover; background-repeat: no-repeat;"> <div class="text-wrapper" style="width:1130px;margin:auto;"> <div class="upper-text"> <h2>Denen, die sagen “unmöglich, nicht machbar, unrealistisch”, erwidern wir:</h2> <h1>Diese Herausforderung nehmen wir an</h1> <p>Wir entwickeln eine innovative neue Medikamentenklasse namens RNAi-Therapeutika von der wir erwarten, dass sie das Leben von Menschen mit gewissen seltenen Krankheiten von Grund auf verändern wird.</p> </div> </div> </div> <div class="mobile-upper-text"> <h2>Denen, die sagen “unmöglich, nicht machbar, unrealistisch”, erwidern wir:</h2> <h1>Diese Herausforderung nehmen wir an</h1> <p>Wir entwickeln eine innovative neue Medikamentenklasse namens RNAi-Therapeutika von der wir erwarten, dass sie das Leben von Menschen mit gewissen seltenen Krankheiten von Grund auf verändern wird.</p> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-banner-overlay paragraph-id--1314 paragraph--view-mode--default"> <div id="clp-banner-overlay"> <div class="banner-text-wrapper" style="width:1130px; margin:auto;"> <div class="text-box"> <section> <h1 class="text-align-center"><strong>AN DER SPITZE DES WANDELS </strong></h1> <p class="text-align-center">RNAi-Therapeutika basieren auf wissenschaftlichen Erkenntnissen, die mit dem Nobelpreis ausgezeichnet wurden. Sie bieten einen wirkungsvollen, klinisch validierten Ansatz zur Behandlung zahlreicher schwerer Krankheiten, die Patienten stark belasten. Das Unternehmen Alnylam ist führend bei der Umsetzung der RNA-Interferenz (RNAi) in eine innovative neue Medikamentenklasse für Patienten mit eingeschränkten oder unzureichenden Behandlungsmöglichkeiten.</p> <p class="text-align-center">Alnylam wurde im Jahr 2002 gegründet und verfolgt eine kühne Vision: Wir verwandeln wissenschaftliches Potenzial in reale Therapien – mit einer robusten Forschungsplattform und zahlreichen Prüfmedikamenten in der Entwicklung, darunter fünf Produktkandidaten, die sich in der Endphase der Untersuchung befinden, und vier Produkte, die von der FDA in den USA, der EMA in der EU und von Swissmedic für die Schweiz zugelassen sind.</p> </section> <div class="counter-box"> <h3 class="text-center"> </h3> <div class="row"> <div class="col-sm-2"> <h1 class="text-align-center">><span>1k</span></h1> <p class="count-text text-align-center">Mitarbeiter</p> </div> <div class="col-sm-2"> <h1 class="text-align-center"><span>19</span></h1> <p class="count-text text-align-center">Länder</p> </div> <div class="col-sm-2"> <h1 class="text-align-center"><span>11</span></h1> <p class="count-text text-align-center">Programme in der klinischen Entwicklung</p> </div> <div class="col-sm-2"> <h1 class="text-align-center"><span>4</span></h1> <p class="count-text text-align-center">Zugelassene Produkte</p> </div> <div class="col-sm-2"> <h1 class="text-align-center">><span>35</span></h1> <p class="count-text text-align-center">Klinische Studien</p> </div> <div class="col-sm-2"> <h1 class="text-align-center">><span>8</span></h1> <p class="count-text text-align-center">Jahre längste Verabreichungsdauer</p> </div> </div> <p class="text-center margin-top-24px"><em>mit Stand vom April 2022</em></p> </div> </div> </div> <div class=" popup-content" style="display:none; background:#fff;"> <div class="field field--name-field-pop-up-field field--type-entity-reference-revisions field--label-hidden field--item"> <div> </div> </div> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-full-bleed-bg paragraph-id--1316 paragraph--view-mode--default"> <div class="paragraph paragraph--type--clp-full-bleed-bg paragraph-id--1316 paragraph--view-mode--default"> <div id="clp-full-bleed-bg" style="background: url(/sites/default/files/2022-01/bleed_1.jpg); background-size: cover; background-repeat: no-repeat;"> <div class="text-wrapper" style="width:900px;margin:auto;"> <h1 class="text-align-center"><strong>RNAi: EINE BIOLOGISCHE REVOLUTION AUF GRUNDLAGE VON FORSCHUNGSARBEITEN, die mit dem Nobelpreis ausgezeichnet wurden</strong></h1> <p class="text-align-center">Die RNA-Interferenz (RNAi) ist ein Durchbruch bei unserem Wissen darüber, wie Gene in Zellen reguliert werden. 2006 ging der Nobelpreis für Physiologie oder Medizin an Craig Mello und Andrew Fire. Damit wurde die Bedeutung der RNAi als wichtige wissenschaftliche Entdeckung anerkannt. Zudem stellt sie einen ganz neuartigen Ansatz bei der Entdeckung und Entwicklung von Medikamenten dar.</p> <p class="text-align-center"><a data-colorbox-inline=".cta-full-bleed-switzerland-german">Weitere Informationen ›</a></p> </div> <div class="cta-full-bleed-switzerland-german popup-content" style="display:none; background:#fff; overflow:hidden;"> <div class="field field--name-field-pop-up-content field--type-entity-reference-revisions field--label-hidden field--item"> <div> <h2 class="text-center">SIE WERDEN WEITERGELEITET</h2> <h4>Sie sind im Begriff, www.alnylam.ch zu verlassen und zu unserer globalen Website (www.alnylam.com) zu gehen, die in englischer Sprache verfasst ist.</h4> <p class="text-center"> <a class="button-more" href="/our-science/the-science-of-rnai" target= "_blank">WEITER</a> </p> </div> </div> </div> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-html-background paragraph-id--1318 paragraph--view-mode--default"> <div id="clp-html-content-background" style="background-color:#f8f8f8;"> <div class="content-wrapper" style="width:1130px; margin:auto; "> <div class="clp-html-background-desc"> <h2 class="text-align-center"><strong>Unser Fokus</strong></h2> <p class="text-align-center">Der Schwerpunkt unserer Forschungsarbeiten im Bereich der RNAi-Therapeutika liegt bei Krankheiten mit hohem ungedecktem medizinischem Bedarf, die in 4 strategische Therapiebereiche (STArs) fallen: genetische Medikamente, Herz- und Stoffwechselkrankheiten, hepatische Infektionskrankheiten und Erkrankungen des zentralen Nervensystems (ZNS) sowie Augenerkrankungen.</p> <p class="text-align-center">Unser zugelassenes Produkt für Patienten in der EU wird bei der Behandlung von vererbbarer ATTR (hATTR) Amyloidose mit Polyneuropathie, der akuten hepatischen Porphyrie (AHP) sowie der primären Hyperoxalurie Typ 1 angewendet. Unsere therapeutischen Produktkandidaten in späten Entwicklungsphasen (Phase 2 bis Phase 3) richten sich vor allem an erbliche ATTR-(hATTR)-Amyloidose, Hämophilie und Blutungserkrankungen, Hypercholesterinämie und komplementvermittelte Erkrankungen.</p> <p class="text-align-center"><a data-colorbox-inline=".cta-html-background-switzerland-german">Sehen Sie sich unsere Pipeline an ›</a></p> </div> <div class="cta-html-background-switzerland-german popup-content" style="display:none; background:#fff; overflow:hidden;"> <div class="field field--name-field-html-pop-up field--type-entity-reference-revisions field--label-hidden field--item"> <div> <h2 class="text-center">SIE WERDEN WEITERGELEITET</h2> <h4>Sie sind im Begriff, www.alnylam.ch zu verlassen und zu unserer globalen Website (www.alnylam.com) zu gehen, die in englischer Sprache verfasst ist.</h4> <p class="text-center"> <a class="button-more" href="/alnylam-rnai-pipeline" target= "_blank">WEITER</a> </p> </div> </div> </div> </div> <div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-left-img-text paragraph-id--1320 paragraph--view-mode--default"> <div id="clp-left-img-text"> <div class="img-text-wrapper" style="width:1130px; margin:auto;"> <div class="img-box"> <div class="field field--name-field-upload-image field--type-image field--label-hidden field--item"> <img src="/sites/default/files/2022-05/bestWorkplace.png" width="696" height="405" alt="" loading="lazy" typeof="foaf:Image" class="img-responsive" /> </div> </div> <div class="text-box"> <h2><strong>Werden Sie Mitglied unseres Teams </strong></h2> <p>Wir verfolgen das Ziel, ein solides biopharmazeutisches Unternehmen aufzubauen, das Patienten mit Medikamenten versorgen kann und kontinuierlich neue Behandlungsmöglichkeiten erforscht. Aus diesem Grund suchen wir Mitarbeiter mit vielfältigen Kenntnissen, Erfahrungen und Werdegängen, um ein globales Team von Weltklasse aufzubauen. Unsere Firmenzentrale befindet sich in Cambridge im US-Bundesstaat Massachusetts. Wir haben Niederlassung und Betriebsstätten in ganz Europa und Asien.</p> <p><a data-colorbox-inline=".cta-left-img-text-switzerland-german">Aktuelle Stellenangebote (in englischer Sprache) ›</a></p> </div> </div> <div class="cta-left-img-text-switzerland-german popup-content" style="display:none; background:#fff;"> <div class="field field--name-field-clp-left-img-text-pop-up field--type-entity-reference-revisions field--label-hidden field--item"> <div> <h2 class="text-center">SIE WERDEN WEITERGELEITET</h2> <h4>Sie sind im Begriff, www.alnylam.ch zu verlassen und zu unserer globalen Website (www.alnylam.com) zu gehen, die in englischer Sprache verfasst ist.</h4> <p class="text-center"> <a class="button-more" href="http://jobs.alnylam.com/" target= "_blank">WEITER</a> </p> </div> </div> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-html-background paragraph-id--1322 paragraph--view-mode--default"> <div id="clp-html-content-background" 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