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overflow: hidden; text-overflow: ellipsis; -webkit-line-clamp: 3; -webkit-box-orient: vertical; }</style><div class="col-xs-12 clearfix"><div class="u-floatLeft"><h1 class="PageHeader-title u-m0x u-fs30">Saliva</h1><div class="u-tcGrayDark">10,611 Followers</div><div class="u-tcGrayDark u-mt2x">Recent papers in <b>Saliva</b></div></div></div></div></div></div><div class="TabbedNavigation"><div class="container"><div class="row"><div class="col-xs-12 clearfix"><ul class="nav u-m0x u-p0x list-inline u-displayFlex"><li class="active"><a href="https://www.academia.edu/Documents/in/Saliva">Top Papers</a></li><li><a href="https://www.academia.edu/Documents/in/Saliva/MostCited">Most Cited Papers</a></li><li><a href="https://www.academia.edu/Documents/in/Saliva/MostDownloaded">Most Downloaded Papers</a></li><li><a href="https://www.academia.edu/Documents/in/Saliva/MostRecent">Newest Papers</a></li><li><a class="" href="https://www.academia.edu/People/Saliva">People</a></li></ul></div><style type="text/css">ul.nav{flex-direction:row}@media(max-width: 567px){ul.nav{flex-direction:column}.TabbedNavigation li{max-width:100%}.TabbedNavigation li.active{background-color:var(--background-grey, #dddde2)}.TabbedNavigation li.active:before,.TabbedNavigation li.active:after{display:none}}</style></div></div></div><div class="container"><div class="row"><div class="col-xs-12"><div class="u-displayFlex"><div class="u-flexGrow1"><div class="works"><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_18755604" data-work_id="18755604" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/18755604/Oxytocin_shapes_parental_motion_during_father_infant_interaction">Oxytocin shapes parental motion during father-infant interaction</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">interaction infant − Oxytocin shapes parental motion during father Supplementary data ml An infant-oriented parental repertoire contributes to an infant's development and well-being. The role of oxytocin (OT) in promoting affiliative... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_18755604" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">interaction infant − Oxytocin shapes parental motion during father Supplementary data ml An infant-oriented parental repertoire contributes to an infant's development and well-being. The role of oxytocin (OT) in promoting affiliative bonds and parenting has been established in numerous animal and human studies. Recently, acute administration of OT to a parent was found to enhance the carer's, but at the same time also the infant's, physiological and behavioural readiness for dyadic social engagement. Yet, the exact cues that are involved in this affiliative transmission process remain unclear. The existing literature suggests that motion and vocalization are key social signals for the offspring that facilitates social participation, and that distance and motion perception are modulated by OT in humans. Here, we employed a computational method on video vignettes of human parent-infant interaction including 32 fathers that were administered OT or a placebo in a crossover experimental design. Results indicate that OT modulates parental proximity to the infant, as well as the father's head speed and head acceleration but not the father's vocalization during dyadic interaction. Similarly, the infant's OT reactivity is positively correlated with father's head acceleration. The current findings are the first to report a relationship between the OT system and parental motion characteristics, further suggesting that the cross-generation transmission of parenting in humans might be underlaid by nuanced, infant-oriented, gestures relating to the carer's proximity, speed and acceleration within the dyadic context.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/18755604" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="f9924d3833ca82f23bcd58564e50ca3c" rel="nofollow" data-download="{"attachment_id":40238056,"asset_id":18755604,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/40238056/download_file?st=MTc0MDAzODkzNCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="38830855" href="https://independent.academia.edu/MohamedChetouani">Mohamed Chetouani</a><script data-card-contents-for-user="38830855" type="text/json">{"id":38830855,"first_name":"Mohamed","last_name":"Chetouani","domain_name":"independent","page_name":"MohamedChetouani","display_name":"Mohamed Chetouani","profile_url":"https://independent.academia.edu/MohamedChetouani?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_18755604 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="18755604"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 18755604, container: ".js-paper-rank-work_18755604", }); 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The role of oxytocin (OT) in promoting affiliative bonds and parenting has been established in numerous animal and human studies. Recently, acute administration of OT to a parent was found to enhance the carer's, but at the same time also the infant's, physiological and behavioural readiness for dyadic social engagement. Yet, the exact cues that are involved in this affiliative transmission process remain unclear. The existing literature suggests that motion and vocalization are key social signals for the offspring that facilitates social participation, and that distance and motion perception are modulated by OT in humans. Here, we employed a computational method on video vignettes of human parent-infant interaction including 32 fathers that were administered OT or a placebo in a crossover experimental design. Results indicate that OT modulates parental proximity to the infant, as well as the father's head speed and head acceleration but not the father's vocalization during dyadic interaction. Similarly, the infant's OT reactivity is positively correlated with father's head acceleration. The current findings are the first to report a relationship between the OT system and parental motion characteristics, further suggesting that the cross-generation transmission of parenting in humans might be underlaid by nuanced, infant-oriented, gestures relating to the carer's proximity, speed and acceleration within the dyadic context.","downloadable_attachments":[{"id":40238056,"asset_id":18755604,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":38830855,"first_name":"Mohamed","last_name":"Chetouani","domain_name":"independent","page_name":"MohamedChetouani","display_name":"Mohamed 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u-fw300 u-lineHeight1_5 u-tcGrayDarkest">Aspectos anatómicos, histológicos, microbiológicos, de la boca. Lengua, saliva y todas las manifestaciones normales que existen en cavidad bucal.</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/28271809" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="1cfa26165e92b7997b7b9ae012a9c51b" rel="nofollow" data-download="{"attachment_id":48597084,"asset_id":28271809,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48597084/download_file?st=MTc0MDAzODkzNCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32377282" href="https://ucuenca.academia.edu/DarwinLSCastilloYaguana">Darwin Castillo Yaguana</a><script data-card-contents-for-user="32377282" type="text/json">{"id":32377282,"first_name":"Darwin","last_name":"Castillo Yaguana","domain_name":"ucuenca","page_name":"DarwinLSCastilloYaguana","display_name":"Darwin Castillo Yaguana","profile_url":"https://ucuenca.academia.edu/DarwinLSCastilloYaguana?f_ri=344106","photo":"https://0.academia-photos.com/32377282/9695365/103721232/s65_darwin.castillo_yaguana.jpeg"}</script></span></span></li><li class="js-paper-rank-work_28271809 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="28271809"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 28271809, container: ".js-paper-rank-work_28271809", }); });</script></li><li class="js-percentile-work_28271809 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 28271809; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_28271809"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_28271809 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="28271809"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 28271809; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=28271809]").text(description); $(".js-view-count-work_28271809").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_28271809").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="28271809"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i></div><span class="InlineList-item-text u-textTruncate u-pl6x"><a class="InlineList-item-text" data-has-card-for-ri="344106" rel="nofollow" href="https://www.academia.edu/Documents/in/Saliva">Saliva</a><script data-card-contents-for-ri="344106" type="text/json">{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (false) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=28271809]'), work: {"id":28271809,"title":"MANIFESTACIONES ORALES DENTRO DE LOS PATRONES DE LA NORMALIDAD","created_at":"2016-09-05T15:16:42.919-07:00","url":"https://www.academia.edu/28271809/MANIFESTACIONES_ORALES_DENTRO_DE_LOS_PATRONES_DE_LA_NORMALIDAD?f_ri=344106","dom_id":"work_28271809","summary":"Aspectos anatómicos, histológicos, microbiológicos, de la boca. Lengua, saliva y todas las manifestaciones normales que existen en cavidad bucal.","downloadable_attachments":[{"id":48597084,"asset_id":28271809,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32377282,"first_name":"Darwin","last_name":"Castillo Yaguana","domain_name":"ucuenca","page_name":"DarwinLSCastilloYaguana","display_name":"Darwin Castillo Yaguana","profile_url":"https://ucuenca.academia.edu/DarwinLSCastilloYaguana?f_ri=344106","photo":"https://0.academia-photos.com/32377282/9695365/103721232/s65_darwin.castillo_yaguana.jpeg"}],"research_interests":[{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106","nofollow":true}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_80080990" data-work_id="80080990" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/80080990/Salivary_Transcriptome_Diagnostics_for_Oral_Cancer_Detection">Salivary Transcriptome Diagnostics for Oral Cancer Detection</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Purpose: Oral fluid (saliva) meets the demand for noninvasive, accessible, and highly efficient diagnostic medium. Recent discovery that a large panel of human RNA can be reliably detected in saliva gives rise to a novel clinical... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_80080990" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Purpose: Oral fluid (saliva) meets the demand for noninvasive, accessible, and highly efficient diagnostic medium. Recent discovery that a large panel of human RNA can be reliably detected in saliva gives rise to a novel clinical approach, salivary transcriptome diagnostics. The purpose of this study is to evaluate the diagnostic value of this new approach by using oral squamous cell carcinoma (OSCC) as the proof-of-principle disease. Experimental Design: Unstimulated saliva was collected from patients (n ‫؍‬ 32) with primary T1/T2 OSCC and normal subjects (n ‫؍‬ 32) with matched age, gender, and smoking history. RNA isolation was done from the saliva supernatant, followed by two-round linear amplification with T7 RNA polymerase. Human Genome U133A microarrays were applied for profiling human salivary transcriptome. The different gene expression patterns were analyzed by combining a t test comparison and a fold-change analysis on 10 matched cancer patients and controls. Quantitative polymerase chain reaction (qPCR) was used to validate the selected genes that showed significant difference (P < 0.01) by microarray. The predictive power of these salivary mRNA biomarkers was analyzed by receiver operating characteristic curve and classification models. Results: Microarray analysis showed there are 1,679 genes exhibited significantly different expression level in saliva between cancer patients and controls (P < 0.05). Seven cancer-related mRNA biomarkers that exhibited at least a 3.5-fold elevation in OSCC saliva (P < 0.01) were consistently validated by qPCR on saliva samples from OSCC patients (n ‫؍‬ 32) and controls (n ‫؍‬ 32). These potential salivary RNA biomarkers are transcripts of IL8,</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/80080990" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="02aab1250228421bee1054affb949d67" rel="nofollow" data-download="{"attachment_id":86581694,"asset_id":80080990,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/86581694/download_file?st=MTc0MDAzODkzNCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="24355139" href="https://independent.academia.edu/RichardJordan4">Richard Jordan</a><script data-card-contents-for-user="24355139" type="text/json">{"id":24355139,"first_name":"Richard","last_name":"Jordan","domain_name":"independent","page_name":"RichardJordan4","display_name":"Richard Jordan","profile_url":"https://independent.academia.edu/RichardJordan4?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_80080990 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="80080990"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 80080990, container: ".js-paper-rank-work_80080990", }); });</script></li><li class="js-percentile-work_80080990 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 80080990; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_80080990"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_80080990 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="80080990"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 80080990; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=80080990]").text(description); $(".js-view-count-work_80080990").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_80080990").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="80080990"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">8</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="7710" rel="nofollow" href="https://www.academia.edu/Documents/in/Biology">Biology</a>, <script data-card-contents-for-ri="7710" type="text/json">{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="315194" rel="nofollow" href="https://www.academia.edu/Documents/in/Oral_Squamous_Cell_Carcinoma_OSCC_">Oral Squamous Cell Carcinoma (OSCC)</a>, <script data-card-contents-for-ri="315194" type="text/json">{"id":315194,"name":"Oral Squamous Cell Carcinoma (OSCC)","url":"https://www.academia.edu/Documents/in/Oral_Squamous_Cell_Carcinoma_OSCC_?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="344106" rel="nofollow" href="https://www.academia.edu/Documents/in/Saliva">Saliva</a><script data-card-contents-for-ri="344106" type="text/json">{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=80080990]'), work: {"id":80080990,"title":"Salivary Transcriptome Diagnostics for Oral Cancer Detection","created_at":"2022-05-27T18:44:14.512-07:00","url":"https://www.academia.edu/80080990/Salivary_Transcriptome_Diagnostics_for_Oral_Cancer_Detection?f_ri=344106","dom_id":"work_80080990","summary":"Purpose: Oral fluid (saliva) meets the demand for noninvasive, accessible, and highly efficient diagnostic medium. Recent discovery that a large panel of human RNA can be reliably detected in saliva gives rise to a novel clinical approach, salivary transcriptome diagnostics. The purpose of this study is to evaluate the diagnostic value of this new approach by using oral squamous cell carcinoma (OSCC) as the proof-of-principle disease. Experimental Design: Unstimulated saliva was collected from patients (n ‫؍‬ 32) with primary T1/T2 OSCC and normal subjects (n ‫؍‬ 32) with matched age, gender, and smoking history. RNA isolation was done from the saliva supernatant, followed by two-round linear amplification with T7 RNA polymerase. Human Genome U133A microarrays were applied for profiling human salivary transcriptome. The different gene expression patterns were analyzed by combining a t test comparison and a fold-change analysis on 10 matched cancer patients and controls. Quantitative polymerase chain reaction (qPCR) was used to validate the selected genes that showed significant difference (P \u003c 0.01) by microarray. The predictive power of these salivary mRNA biomarkers was analyzed by receiver operating characteristic curve and classification models. Results: Microarray analysis showed there are 1,679 genes exhibited significantly different expression level in saliva between cancer patients and controls (P \u003c 0.05). Seven cancer-related mRNA biomarkers that exhibited at least a 3.5-fold elevation in OSCC saliva (P \u003c 0.01) were consistently validated by qPCR on saliva samples from OSCC patients (n ‫؍‬ 32) and controls (n ‫؍‬ 32). These potential salivary RNA biomarkers are transcripts of IL8,","downloadable_attachments":[{"id":86581694,"asset_id":80080990,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":24355139,"first_name":"Richard","last_name":"Jordan","domain_name":"independent","page_name":"RichardJordan4","display_name":"Richard Jordan","profile_url":"https://independent.academia.edu/RichardJordan4?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=344106","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=344106","nofollow":true},{"id":315194,"name":"Oral Squamous Cell Carcinoma (OSCC)","url":"https://www.academia.edu/Documents/in/Oral_Squamous_Cell_Carcinoma_OSCC_?f_ri=344106","nofollow":true},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106","nofollow":true},{"id":375141,"name":"Mouth Neoplasms","url":"https://www.academia.edu/Documents/in/Mouth_Neoplasms?f_ri=344106"},{"id":1810445,"name":"Gene expression profiling","url":"https://www.academia.edu/Documents/in/Gene_expression_profiling?f_ri=344106"},{"id":1819399,"name":"Case Control Studies","url":"https://www.academia.edu/Documents/in/Case_Control_Studies?f_ri=344106"},{"id":3067128,"name":"reverse transcriptase polymerase chain reaction","url":"https://www.academia.edu/Documents/in/reverse_transcriptase_polymerase_chain_reaction?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_79315376" data-work_id="79315376" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/79315376/Within_Subject_Reliability_and_between_Subject_Variability_of_Oxidative_Stress_Markers_in_Saliva_of_Healthy_Subjects_A_Longitudinal_Pilot_Study">Within-Subject Reliability and between-Subject Variability of Oxidative Stress Markers in Saliva of Healthy Subjects: A Longitudinal Pilot Study</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The present study evaluated diurnal variations and day-to-day fluctuations of salivary oxidative stress (OS) markers in healthy adult individuals. Whole unstimulated saliva was collected at 2 time intervals over 3 consecutive days.... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_79315376" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The present study evaluated diurnal variations and day-to-day fluctuations of salivary oxidative stress (OS) markers in healthy adult individuals. Whole unstimulated saliva was collected at 2 time intervals over 3 consecutive days. Glutathione peroxidase (GPX), superoxide dismutase (SOD), total antioxidant capacity (TAC), and uric acid (UA) were analyzed using spectrophotometric methods, while 8-hydroxydeoxyguanosine (8-OHdG) and malondialdehyde (MDA) were determined using immunoassays. No significant differences for salivary OS markers between men and women were observed. For all examined OS markers, no significant day-to-day variations were demonstrated. Significant diurnal variations were found in salivary GPX, TAC and MDA levels. For SOD, TAC, GPX, and UA, good-to-moderate intraindividual coefficients of variations (CVs) were observed in more than 75% of the subjects. For MDA and 8-OHdG, intraindividual CVs &gt; 35% were observed in 60% and 40% of the subjects, respectively. Bet...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/79315376" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="0936f89c84a91607d1b84c238a5ee800" rel="nofollow" data-download="{"attachment_id":86071634,"asset_id":79315376,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/86071634/download_file?st=MTc0MDAzODkzNCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="101875209" href="https://independent.academia.edu/IvanaLapi%C4%87">Ivana Lapić</a><script data-card-contents-for-user="101875209" type="text/json">{"id":101875209,"first_name":"Ivana","last_name":"Lapić","domain_name":"independent","page_name":"IvanaLapić","display_name":"Ivana Lapić","profile_url":"https://independent.academia.edu/IvanaLapi%C4%87?f_ri=344106","photo":"https://0.academia-photos.com/101875209/23574923/22621141/s65_ivana.lapi_.jpg"}</script></span></span></li><li class="js-paper-rank-work_79315376 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="79315376"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 79315376, container: ".js-paper-rank-work_79315376", }); 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$(".js-view-count[data-work-id=79315376]").text(description); $(".js-view-count-work_79315376").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_79315376").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="79315376"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">4</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="14292" rel="nofollow" href="https://www.academia.edu/Documents/in/Oxidative_Stress">Oxidative Stress</a>, <script data-card-contents-for-ri="14292" type="text/json">{"id":14292,"name":"Oxidative Stress","url":"https://www.academia.edu/Documents/in/Oxidative_Stress?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="186234" rel="nofollow" href="https://www.academia.edu/Documents/in/Medical_Physiology">Medical Physiology</a>, <script data-card-contents-for-ri="186234" type="text/json">{"id":186234,"name":"Medical Physiology","url":"https://www.academia.edu/Documents/in/Medical_Physiology?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="344106" rel="nofollow" href="https://www.academia.edu/Documents/in/Saliva">Saliva</a><script data-card-contents-for-ri="344106" type="text/json">{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=79315376]'), work: {"id":79315376,"title":"Within-Subject Reliability and between-Subject Variability of Oxidative Stress Markers in Saliva of Healthy Subjects: A Longitudinal Pilot Study","created_at":"2022-05-17T08:31:48.431-07:00","url":"https://www.academia.edu/79315376/Within_Subject_Reliability_and_between_Subject_Variability_of_Oxidative_Stress_Markers_in_Saliva_of_Healthy_Subjects_A_Longitudinal_Pilot_Study?f_ri=344106","dom_id":"work_79315376","summary":"The present study evaluated diurnal variations and day-to-day fluctuations of salivary oxidative stress (OS) markers in healthy adult individuals. Whole unstimulated saliva was collected at 2 time intervals over 3 consecutive days. Glutathione peroxidase (GPX), superoxide dismutase (SOD), total antioxidant capacity (TAC), and uric acid (UA) were analyzed using spectrophotometric methods, while 8-hydroxydeoxyguanosine (8-OHdG) and malondialdehyde (MDA) were determined using immunoassays. No significant differences for salivary OS markers between men and women were observed. For all examined OS markers, no significant day-to-day variations were demonstrated. Significant diurnal variations were found in salivary GPX, TAC and MDA levels. For SOD, TAC, GPX, and UA, good-to-moderate intraindividual coefficients of variations (CVs) were observed in more than 75% of the subjects. For MDA and 8-OHdG, intraindividual CVs \u0026gt; 35% were observed in 60% and 40% of the subjects, respectively. Bet...","downloadable_attachments":[{"id":86071634,"asset_id":79315376,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":101875209,"first_name":"Ivana","last_name":"Lapić","domain_name":"independent","page_name":"IvanaLapić","display_name":"Ivana Lapić","profile_url":"https://independent.academia.edu/IvanaLapi%C4%87?f_ri=344106","photo":"https://0.academia-photos.com/101875209/23574923/22621141/s65_ivana.lapi_.jpg"}],"research_interests":[{"id":14292,"name":"Oxidative Stress","url":"https://www.academia.edu/Documents/in/Oxidative_Stress?f_ri=344106","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=344106","nofollow":true},{"id":186234,"name":"Medical Physiology","url":"https://www.academia.edu/Documents/in/Medical_Physiology?f_ri=344106","nofollow":true},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106","nofollow":true}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_60990403" data-work_id="60990403" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/60990403/The_implicit_affiliation_motive_moderates_cortisol_responses_to_acute_psychosocial_stress_in_high_school_students">The implicit affiliation motive moderates cortisol responses to acute psychosocial stress in high school students</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">It has been previously shown that the implicit affiliation motive-the need to establish and maintain friendly relationships with others-leads to chronic health benefits. The underlying assumption for the present research was that the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_60990403" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">It has been previously shown that the implicit affiliation motive-the need to establish and maintain friendly relationships with others-leads to chronic health benefits. The underlying assumption for the present research was that the implicit affiliation motive also moderates the salivary cortisol response to acute psychological stress when some aspects of social evaluation and uncontrollability are involved. By contrast we did not expect similar effects in response to exercise as a physical stressor. Fifty-nine high school students aged M = 14.8 years were randomly assigned to a psychosocial stress (publishing the results of an intelligence test performed), a physical stress (exercise intensity of 65-75% of HR max), and a control condition (normal school lesson) each lasting 15 min. Participants' affiliation motives were assessed using the Operant Motive Test and salivary cortisol samples were taken pre and post stressor. We found that the strength of the affiliation motive negatively predicted cortisol reactions to acute psychosocial but not to physical stress when compared to a control group. The results suggest that the affiliation motive buffers the effect of acute psychosocial stress on the HPA axis.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/60990403" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="1ddd2fe4ec5dc36f99f371325ebc118a" rel="nofollow" data-download="{"attachment_id":74192424,"asset_id":60990403,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/74192424/download_file?st=MTc0MDAzODkzNCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="65627136" href="https://independent.academia.edu/HenningBudde">Henning Budde</a><script data-card-contents-for-user="65627136" type="text/json">{"id":65627136,"first_name":"Henning","last_name":"Budde","domain_name":"independent","page_name":"HenningBudde","display_name":"Henning Budde","profile_url":"https://independent.academia.edu/HenningBudde?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_60990403 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="60990403"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 60990403, container: ".js-paper-rank-work_60990403", }); });</script></li><li class="js-percentile-work_60990403 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 60990403; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_60990403"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_60990403 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="60990403"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 60990403; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=60990403]").text(description); $(".js-view-count-work_60990403").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_60990403").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="60990403"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">15</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="46406" rel="nofollow" href="https://www.academia.edu/Documents/in/Motivation">Motivation</a>, <script data-card-contents-for-ri="46406" type="text/json">{"id":46406,"name":"Motivation","url":"https://www.academia.edu/Documents/in/Motivation?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="49610" rel="nofollow" href="https://www.academia.edu/Documents/in/Schools">Schools</a>, <script data-card-contents-for-ri="49610" type="text/json">{"id":49610,"name":"Schools","url":"https://www.academia.edu/Documents/in/Schools?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="56132" rel="nofollow" href="https://www.academia.edu/Documents/in/Students">Students</a><script data-card-contents-for-ri="56132" type="text/json">{"id":56132,"name":"Students","url":"https://www.academia.edu/Documents/in/Students?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=60990403]'), work: {"id":60990403,"title":"The implicit affiliation motive moderates cortisol responses to acute psychosocial stress in high school students","created_at":"2021-11-04T03:07:16.280-07:00","url":"https://www.academia.edu/60990403/The_implicit_affiliation_motive_moderates_cortisol_responses_to_acute_psychosocial_stress_in_high_school_students?f_ri=344106","dom_id":"work_60990403","summary":"It has been previously shown that the implicit affiliation motive-the need to establish and maintain friendly relationships with others-leads to chronic health benefits. The underlying assumption for the present research was that the implicit affiliation motive also moderates the salivary cortisol response to acute psychological stress when some aspects of social evaluation and uncontrollability are involved. By contrast we did not expect similar effects in response to exercise as a physical stressor. Fifty-nine high school students aged M = 14.8 years were randomly assigned to a psychosocial stress (publishing the results of an intelligence test performed), a physical stress (exercise intensity of 65-75% of HR max), and a control condition (normal school lesson) each lasting 15 min. Participants' affiliation motives were assessed using the Operant Motive Test and salivary cortisol samples were taken pre and post stressor. We found that the strength of the affiliation motive negatively predicted cortisol reactions to acute psychosocial but not to physical stress when compared to a control group. The results suggest that the affiliation motive buffers the effect of acute psychosocial stress on the HPA axis.","downloadable_attachments":[{"id":74192424,"asset_id":60990403,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":65627136,"first_name":"Henning","last_name":"Budde","domain_name":"independent","page_name":"HenningBudde","display_name":"Henning Budde","profile_url":"https://independent.academia.edu/HenningBudde?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=344106","nofollow":true},{"id":46406,"name":"Motivation","url":"https://www.academia.edu/Documents/in/Motivation?f_ri=344106","nofollow":true},{"id":49610,"name":"Schools","url":"https://www.academia.edu/Documents/in/Schools?f_ri=344106","nofollow":true},{"id":56132,"name":"Students","url":"https://www.academia.edu/Documents/in/Students?f_ri=344106","nofollow":true},{"id":130446,"name":"Social Skills","url":"https://www.academia.edu/Documents/in/Social_Skills?f_ri=344106"},{"id":133761,"name":"Psychoneuroendocrinology","url":"https://www.academia.edu/Documents/in/Psychoneuroendocrinology?f_ri=344106"},{"id":172809,"name":"Interpersonal Relations","url":"https://www.academia.edu/Documents/in/Interpersonal_Relations?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":644084,"name":"Intelligence tests","url":"https://www.academia.edu/Documents/in/Intelligence_tests?f_ri=344106"},{"id":1146831,"name":"Exercise Test","url":"https://www.academia.edu/Documents/in/Exercise_Test?f_ri=344106"},{"id":1201074,"name":"Psychological Stress","url":"https://www.academia.edu/Documents/in/Psychological_Stress?f_ri=344106"},{"id":2471455,"name":"Acute Disease","url":"https://www.academia.edu/Documents/in/Acute_Disease?f_ri=344106"},{"id":2922956,"name":"Psychology and Cognitive Sciences","url":"https://www.academia.edu/Documents/in/Psychology_and_Cognitive_Sciences?f_ri=344106"},{"id":3359206,"name":"hydrocortisone","url":"https://www.academia.edu/Documents/in/hydrocortisone?f_ri=344106"},{"id":3763225,"name":"Medical and Health Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_56679774" data-work_id="56679774" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/56679774/Modification_of_the_skin_feeding_site_by_tick_saliva_mediates_virus_transmission">Modification of the skin feeding site by tick saliva mediates virus transmission</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">A tick vector of Thogoto (THO) virus was Shown to secrete a factor in saliva which potentiates the transmission of THO virus to uninfected ticks feeding on an apparently non-viraemic host. The effect of the saliva activated transmission... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_56679774" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">A tick vector of Thogoto (THO) virus was Shown to secrete a factor in saliva which potentiates the transmission of THO virus to uninfected ticks feeding on an apparently non-viraemic host. The effect of the saliva activated transmission (SAT) factor on the virus occurred at the site of inoculation in the skin and was apparent even when the virus was introduced 3 days after the SAT factor, The results suggest that tick saliva can play an important role in disease transmission by virtue of host modification at the site of feeding.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/56679774" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="bca4beffbb5de8389dcb768ac94c2552" rel="nofollow" data-download="{"attachment_id":71946597,"asset_id":56679774,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/71946597/download_file?st=MTc0MDAzODkzNCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="43121212" href="https://independent.academia.edu/ReubenKaufman">Reuben Kaufman</a><script data-card-contents-for-user="43121212" type="text/json">{"id":43121212,"first_name":"Reuben","last_name":"Kaufman","domain_name":"independent","page_name":"ReubenKaufman","display_name":"Reuben Kaufman","profile_url":"https://independent.academia.edu/ReubenKaufman?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_56679774 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="56679774"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 56679774, container: ".js-paper-rank-work_56679774", }); });</script></li><li class="js-percentile-work_56679774 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 56679774; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_56679774"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_56679774 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="56679774"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 56679774; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=56679774]").text(description); $(".js-view-count-work_56679774").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_56679774").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="56679774"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">13</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="167" rel="nofollow" href="https://www.academia.edu/Documents/in/Physiology">Physiology</a>, <script data-card-contents-for-ri="167" type="text/json">{"id":167,"name":"Physiology","url":"https://www.academia.edu/Documents/in/Physiology?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="43754" rel="nofollow" href="https://www.academia.edu/Documents/in/Ticks">Ticks</a>, <script data-card-contents-for-ri="43754" type="text/json">{"id":43754,"name":"Ticks","url":"https://www.academia.edu/Documents/in/Ticks?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="57570" rel="nofollow" href="https://www.academia.edu/Documents/in/Cercopithecus_aethiops">Cercopithecus aethiops</a>, <script data-card-contents-for-ri="57570" type="text/json">{"id":57570,"name":"Cercopithecus aethiops","url":"https://www.academia.edu/Documents/in/Cercopithecus_aethiops?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="162553" rel="nofollow" href="https://www.academia.edu/Documents/in/Skin">Skin</a><script data-card-contents-for-ri="162553" type="text/json">{"id":162553,"name":"Skin","url":"https://www.academia.edu/Documents/in/Skin?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=56679774]'), work: {"id":56679774,"title":"Modification of the skin feeding site by tick saliva mediates virus transmission","created_at":"2021-10-08T17:38:33.081-07:00","url":"https://www.academia.edu/56679774/Modification_of_the_skin_feeding_site_by_tick_saliva_mediates_virus_transmission?f_ri=344106","dom_id":"work_56679774","summary":"A tick vector of Thogoto (THO) virus was Shown to secrete a factor in saliva which potentiates the transmission of THO virus to uninfected ticks feeding on an apparently non-viraemic host. The effect of the saliva activated transmission (SAT) factor on the virus occurred at the site of inoculation in the skin and was apparent even when the virus was introduced 3 days after the SAT factor, The results suggest that tick saliva can play an important role in disease transmission by virtue of host modification at the site of feeding.","downloadable_attachments":[{"id":71946597,"asset_id":56679774,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":43121212,"first_name":"Reuben","last_name":"Kaufman","domain_name":"independent","page_name":"ReubenKaufman","display_name":"Reuben Kaufman","profile_url":"https://independent.academia.edu/ReubenKaufman?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":167,"name":"Physiology","url":"https://www.academia.edu/Documents/in/Physiology?f_ri=344106","nofollow":true},{"id":43754,"name":"Ticks","url":"https://www.academia.edu/Documents/in/Ticks?f_ri=344106","nofollow":true},{"id":57570,"name":"Cercopithecus aethiops","url":"https://www.academia.edu/Documents/in/Cercopithecus_aethiops?f_ri=344106","nofollow":true},{"id":162553,"name":"Skin","url":"https://www.academia.edu/Documents/in/Skin?f_ri=344106","nofollow":true},{"id":202574,"name":"Feeding Behavior","url":"https://www.academia.edu/Documents/in/Feeding_Behavior?f_ri=344106"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":762757,"name":"Arboviruses","url":"https://www.academia.edu/Documents/in/Arboviruses?f_ri=344106"},{"id":1007684,"name":"Virus diseases","url":"https://www.academia.edu/Documents/in/Virus_diseases?f_ri=344106"},{"id":1681026,"name":"Biochemistry and cell biology","url":"https://www.academia.edu/Documents/in/Biochemistry_and_cell_biology?f_ri=344106"},{"id":2826825,"name":"Arthropod vectors","url":"https://www.academia.edu/Documents/in/Arthropod_vectors?f_ri=344106"},{"id":3649433,"name":"disease transmission","url":"https://www.academia.edu/Documents/in/disease_transmission?f_ri=344106"},{"id":3769209,"name":"Guinea pigs","url":"https://www.academia.edu/Documents/in/Guinea_pigs?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_74832869" data-work_id="74832869" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/74832869/Salivary_protein_characteristics_from_saliva_of_carious_lesionfree_and_high_caries_adults">Salivary protein characteristics from saliva of carious lesionfree and high caries adults</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">It has been argued that specific salivary proteins could have a protective effect against caries, but data from the many available studies are rather contradictory. The purpose of this study was to analyze whether there is a relationship... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_74832869" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">It has been argued that specific salivary proteins could have a protective effect against caries, but data from the many available studies are rather contradictory. The purpose of this study was to analyze whether there is a relationship between protein concentration, electrophoretic profile and concentration of salivary IgA and the presence or absence of caries in adults. Adults with high caries activity (HC) and without caries lesions (CF), assessed by ICDAS criteria, were asked to provide unstimulated saliva samples. Protein concentration (μg/mL) was determined using the Bradford method. Western blotting was used to detect IgA. Data were compared using Student&#39;s t test at p&lt;0.05. Total protein concentration in CF was higher (50.65±7.5 μg/mL) than in HC individuals (26.80±2.5 μg/mL) (p=0.001). More protein bands were visualized in the gels from CF than the HC group (p=0.001). CF subjects showed higher salivary IgA concentration (11.27±0.5 μg) than HC individuals (1.71±0.2μg...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/74832869" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="abf89a07d2139c3b0e16cced4c512d59" rel="nofollow" data-download="{"attachment_id":82843472,"asset_id":74832869,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/82843472/download_file?st=MTc0MDAzODkzNCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="37631100" href="https://utalca.academia.edu/RodrigoAGiacaman">Rodrigo A. Giacaman</a><script data-card-contents-for-user="37631100" type="text/json">{"id":37631100,"first_name":"Rodrigo A.","last_name":"Giacaman","domain_name":"utalca","page_name":"RodrigoAGiacaman","display_name":"Rodrigo A. Giacaman","profile_url":"https://utalca.academia.edu/RodrigoAGiacaman?f_ri=344106","photo":"https://0.academia-photos.com/37631100/11115159/12404207/s65_rodrigo_a..giacaman.jpg"}</script></span></span></li><li class="js-paper-rank-work_74832869 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="74832869"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 74832869, container: ".js-paper-rank-work_74832869", }); });</script></li><li class="js-percentile-work_74832869 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 74832869; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_74832869"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_74832869 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="74832869"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 74832869; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=74832869]").text(description); $(".js-view-count-work_74832869").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_74832869").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="74832869"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">5</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="159" rel="nofollow" href="https://www.academia.edu/Documents/in/Microbiology">Microbiology</a>, <script data-card-contents-for-ri="159" type="text/json">{"id":159,"name":"Microbiology","url":"https://www.academia.edu/Documents/in/Microbiology?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="1290" rel="nofollow" href="https://www.academia.edu/Documents/in/Immunology">Immunology</a>, <script data-card-contents-for-ri="1290" type="text/json">{"id":1290,"name":"Immunology","url":"https://www.academia.edu/Documents/in/Immunology?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="105826" rel="nofollow" href="https://www.academia.edu/Documents/in/Dental_Caries">Dental Caries</a>, <script data-card-contents-for-ri="105826" type="text/json">{"id":105826,"name":"Dental Caries","url":"https://www.academia.edu/Documents/in/Dental_Caries?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="133057" rel="nofollow" href="https://www.academia.edu/Documents/in/Young_Adult">Young Adult</a><script data-card-contents-for-ri="133057" type="text/json">{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=74832869]'), work: {"id":74832869,"title":"Salivary protein characteristics from saliva of carious lesionfree and high caries adults","created_at":"2022-03-28T17:46:21.723-07:00","url":"https://www.academia.edu/74832869/Salivary_protein_characteristics_from_saliva_of_carious_lesionfree_and_high_caries_adults?f_ri=344106","dom_id":"work_74832869","summary":"It has been argued that specific salivary proteins could have a protective effect against caries, but data from the many available studies are rather contradictory. The purpose of this study was to analyze whether there is a relationship between protein concentration, electrophoretic profile and concentration of salivary IgA and the presence or absence of caries in adults. Adults with high caries activity (HC) and without caries lesions (CF), assessed by ICDAS criteria, were asked to provide unstimulated saliva samples. Protein concentration (μg/mL) was determined using the Bradford method. Western blotting was used to detect IgA. Data were compared using Student\u0026#39;s t test at p\u0026lt;0.05. Total protein concentration in CF was higher (50.65±7.5 μg/mL) than in HC individuals (26.80±2.5 μg/mL) (p=0.001). More protein bands were visualized in the gels from CF than the HC group (p=0.001). CF subjects showed higher salivary IgA concentration (11.27±0.5 μg) than HC individuals (1.71±0.2μg...","downloadable_attachments":[{"id":82843472,"asset_id":74832869,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":37631100,"first_name":"Rodrigo A.","last_name":"Giacaman","domain_name":"utalca","page_name":"RodrigoAGiacaman","display_name":"Rodrigo A. Giacaman","profile_url":"https://utalca.academia.edu/RodrigoAGiacaman?f_ri=344106","photo":"https://0.academia-photos.com/37631100/11115159/12404207/s65_rodrigo_a..giacaman.jpg"}],"research_interests":[{"id":159,"name":"Microbiology","url":"https://www.academia.edu/Documents/in/Microbiology?f_ri=344106","nofollow":true},{"id":1290,"name":"Immunology","url":"https://www.academia.edu/Documents/in/Immunology?f_ri=344106","nofollow":true},{"id":105826,"name":"Dental Caries","url":"https://www.academia.edu/Documents/in/Dental_Caries?f_ri=344106","nofollow":true},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=344106","nofollow":true},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_66013688" data-work_id="66013688" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/66013688/Preliminary_Buprenorphine_Sublingual_Tablet_Pharmacokinetic_Data_in_Plasma_Oral_Fluid_and_Sweat_During_Treatment_of_Opioid_Dependent_Pregnant_Women">Preliminary Buprenorphine Sublingual Tablet Pharmacokinetic Data in Plasma, Oral Fluid, and Sweat During Treatment of Opioid-Dependent Pregnant Women</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Background-Buprenorphine is currently under investigation as a pharmacotherapy to treat pregnant women for opioid dependence. This research evaluates buprenorphine (BUP), norbuprenophine (NBUP), buprenorphine-glucuronide (BUP-Gluc) and... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_66013688" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Background-Buprenorphine is currently under investigation as a pharmacotherapy to treat pregnant women for opioid dependence. This research evaluates buprenorphine (BUP), norbuprenophine (NBUP), buprenorphine-glucuronide (BUP-Gluc) and norbuprenorphineglucuronide (NBUP-Gluc) pharmacokinetics after high dose (14-20 mg) BUP sublingual tablet administration in three opioid-dependent pregnant women. Methods-Oral fluid and sweat specimens were collected in addition to plasma specimens for 24 h during gestation weeks 28 or 29 and 34, and 2 months after delivery. T max was not affected by pregnancy; however, BUP and NBUP C max and AUC 0-24h tended to be lower during pregnancy compared to postpartum levels. Results-Statistically significant but weak positive correlations were found for BUP plasma and OF concentrations, and BUP/NBUP ratios in plasma and OF. Conclusion-Statistically significant negative correlations were observed for times of specimen collection and BUP and NBUP OF/plasma ratios. BUP-Gluc and NBUP-Gluc were detected in only 5% of OF specimens. In sweat, BUP and NBUP were detected in only 4 of 25 (12 or 24 h) specimens in low concentrations (<2.4 ng/patch). These preliminary data describe BUP and metabolite pharmacokinetics in pregnant women and suggest that, like methadone, upward dose adjustments may be needed with advancing gestation.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/66013688" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="1e9df1883479ac4708d57f2be6b66feb" rel="nofollow" data-download="{"attachment_id":77368649,"asset_id":66013688,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/77368649/download_file?st=MTc0MDAzODkzNCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="61154020" href="https://independent.academia.edu/MartaConcheiroGuisan">Marta Concheiro-Guisan</a><script data-card-contents-for-user="61154020" type="text/json">{"id":61154020,"first_name":"Marta","last_name":"Concheiro-Guisan","domain_name":"independent","page_name":"MartaConcheiroGuisan","display_name":"Marta Concheiro-Guisan","profile_url":"https://independent.academia.edu/MartaConcheiroGuisan?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_66013688 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="66013688"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 66013688, container: ".js-paper-rank-work_66013688", }); });</script></li><li class="js-percentile-work_66013688 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 66013688; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_66013688"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_66013688 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="66013688"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 66013688; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=66013688]").text(description); $(".js-view-count-work_66013688").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_66013688").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="66013688"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">10</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="524" rel="nofollow" href="https://www.academia.edu/Documents/in/Analytical_Chemistry">Analytical Chemistry</a>, <script data-card-contents-for-ri="524" type="text/json">{"id":524,"name":"Analytical Chemistry","url":"https://www.academia.edu/Documents/in/Analytical_Chemistry?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="58380" rel="nofollow" href="https://www.academia.edu/Documents/in/Therapeutic_drug_monitoring">Therapeutic drug monitoring</a>, <script data-card-contents-for-ri="58380" type="text/json">{"id":58380,"name":"Therapeutic drug monitoring","url":"https://www.academia.edu/Documents/in/Therapeutic_drug_monitoring?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62550" rel="nofollow" href="https://www.academia.edu/Documents/in/Pregnancy">Pregnancy</a><script data-card-contents-for-ri="62550" type="text/json">{"id":62550,"name":"Pregnancy","url":"https://www.academia.edu/Documents/in/Pregnancy?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=66013688]'), work: {"id":66013688,"title":"Preliminary Buprenorphine Sublingual Tablet Pharmacokinetic Data in Plasma, Oral Fluid, and Sweat During Treatment of Opioid-Dependent Pregnant Women","created_at":"2021-12-26T04:24:47.549-08:00","url":"https://www.academia.edu/66013688/Preliminary_Buprenorphine_Sublingual_Tablet_Pharmacokinetic_Data_in_Plasma_Oral_Fluid_and_Sweat_During_Treatment_of_Opioid_Dependent_Pregnant_Women?f_ri=344106","dom_id":"work_66013688","summary":"Background-Buprenorphine is currently under investigation as a pharmacotherapy to treat pregnant women for opioid dependence. This research evaluates buprenorphine (BUP), norbuprenophine (NBUP), buprenorphine-glucuronide (BUP-Gluc) and norbuprenorphineglucuronide (NBUP-Gluc) pharmacokinetics after high dose (14-20 mg) BUP sublingual tablet administration in three opioid-dependent pregnant women. Methods-Oral fluid and sweat specimens were collected in addition to plasma specimens for 24 h during gestation weeks 28 or 29 and 34, and 2 months after delivery. T max was not affected by pregnancy; however, BUP and NBUP C max and AUC 0-24h tended to be lower during pregnancy compared to postpartum levels. Results-Statistically significant but weak positive correlations were found for BUP plasma and OF concentrations, and BUP/NBUP ratios in plasma and OF. Conclusion-Statistically significant negative correlations were observed for times of specimen collection and BUP and NBUP OF/plasma ratios. BUP-Gluc and NBUP-Gluc were detected in only 5% of OF specimens. In sweat, BUP and NBUP were detected in only 4 of 25 (12 or 24 h) specimens in low concentrations (\u003c2.4 ng/patch). These preliminary data describe BUP and metabolite pharmacokinetics in pregnant women and suggest that, like methadone, upward dose adjustments may be needed with advancing gestation.","downloadable_attachments":[{"id":77368649,"asset_id":66013688,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":61154020,"first_name":"Marta","last_name":"Concheiro-Guisan","domain_name":"independent","page_name":"MartaConcheiroGuisan","display_name":"Marta Concheiro-Guisan","profile_url":"https://independent.academia.edu/MartaConcheiroGuisan?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":524,"name":"Analytical Chemistry","url":"https://www.academia.edu/Documents/in/Analytical_Chemistry?f_ri=344106","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=344106","nofollow":true},{"id":58380,"name":"Therapeutic drug monitoring","url":"https://www.academia.edu/Documents/in/Therapeutic_drug_monitoring?f_ri=344106","nofollow":true},{"id":62550,"name":"Pregnancy","url":"https://www.academia.edu/Documents/in/Pregnancy?f_ri=344106","nofollow":true},{"id":143599,"name":"Buprenorphine","url":"https://www.academia.edu/Documents/in/Buprenorphine?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":793577,"name":"Sweat","url":"https://www.academia.edu/Documents/in/Sweat?f_ri=344106"},{"id":1309706,"name":"Area Under Curve","url":"https://www.academia.edu/Documents/in/Area_Under_Curve?f_ri=344106"},{"id":3067129,"name":"postpartum period","url":"https://www.academia.edu/Documents/in/postpartum_period?f_ri=344106"},{"id":3789884,"name":"Pharmacology and pharmaceutical sciences","url":"https://www.academia.edu/Documents/in/Pharmacology_and_pharmaceutical_sciences?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_61465373" data-work_id="61465373" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/61465373/Salivary_Biomarkers_and_Training_Load_During_Training_and_Competition_in_Paralympic_Swimmers">Salivary Biomarkers and Training Load During Training and Competition in Paralympic Swimmers</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Stress responses in athletes can be attributed to training and competition, where increased physiological and psychological stress may negatively affect performance and recovery. To examine the relationship between training load (TL) and... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_61465373" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Stress responses in athletes can be attributed to training and competition, where increased physiological and psychological stress may negatively affect performance and recovery. To examine the relationship between training load (TL) and salivary biomarkers immunoglobulin A (IgA), alpha-amylase (AA), and cortisol across a 16-wk preparation phase and 10-d competition phase in Paralympic swimmers. Four Paralympic swimmers provided biweekly saliva samples during 3 training phases-(1) normal training, (2) intensified training, and (3) taper-as well as daily saliva samples in the 10-d Paralympic competition (2016 Paralympic Games). TL was measured using session rating of perceived exertion. Multilevel analysis identified a significant increase in salivary immunoglobulin A (sIgA: 94.98 [27.69] μg·mL), salivary alpha-amylase (sAA: 45.78 [19.07] μg·mL), and salivary cortisol (7.92 [2.17] nM) during intensified training concurrent with a 38.3% increase in TL. During the taper phase, a 49.5% ...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/61465373" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="ac62b1fcafca33ee3e204eeb04c5e31a" rel="nofollow" data-download="{"attachment_id":74487865,"asset_id":61465373,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/74487865/download_file?st=MTc0MDAzODkzNCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="69986673" href="https://limerick.academia.edu/CiaraOConnor">Ciara O'Connor</a><script data-card-contents-for-user="69986673" type="text/json">{"id":69986673,"first_name":"Ciara","last_name":"O'Connor","domain_name":"limerick","page_name":"CiaraOConnor","display_name":"Ciara O'Connor","profile_url":"https://limerick.academia.edu/CiaraOConnor?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_61465373 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="61465373"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 61465373, container: ".js-paper-rank-work_61465373", }); });</script></li><li class="js-percentile-work_61465373 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 61465373; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_61465373"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_61465373 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="61465373"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 61465373; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=61465373]").text(description); $(".js-view-count-work_61465373").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_61465373").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="61465373"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">10</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="6970" rel="nofollow" href="https://www.academia.edu/Documents/in/Biomarkers">Biomarkers</a>, <script data-card-contents-for-ri="6970" type="text/json">{"id":6970,"name":"Biomarkers","url":"https://www.academia.edu/Documents/in/Biomarkers?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="28582" rel="nofollow" href="https://www.academia.edu/Documents/in/Swimming">Swimming</a>, <script data-card-contents-for-ri="28582" type="text/json">{"id":28582,"name":"Swimming","url":"https://www.academia.edu/Documents/in/Swimming?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="133057" rel="nofollow" href="https://www.academia.edu/Documents/in/Young_Adult">Young Adult</a><script data-card-contents-for-ri="133057" type="text/json">{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=61465373]'), work: {"id":61465373,"title":"Salivary Biomarkers and Training Load During Training and Competition in Paralympic Swimmers","created_at":"2021-11-10T05:28:21.326-08:00","url":"https://www.academia.edu/61465373/Salivary_Biomarkers_and_Training_Load_During_Training_and_Competition_in_Paralympic_Swimmers?f_ri=344106","dom_id":"work_61465373","summary":"Stress responses in athletes can be attributed to training and competition, where increased physiological and psychological stress may negatively affect performance and recovery. To examine the relationship between training load (TL) and salivary biomarkers immunoglobulin A (IgA), alpha-amylase (AA), and cortisol across a 16-wk preparation phase and 10-d competition phase in Paralympic swimmers. Four Paralympic swimmers provided biweekly saliva samples during 3 training phases-(1) normal training, (2) intensified training, and (3) taper-as well as daily saliva samples in the 10-d Paralympic competition (2016 Paralympic Games). TL was measured using session rating of perceived exertion. Multilevel analysis identified a significant increase in salivary immunoglobulin A (sIgA: 94.98 [27.69] μg·mL), salivary alpha-amylase (sAA: 45.78 [19.07] μg·mL), and salivary cortisol (7.92 [2.17] nM) during intensified training concurrent with a 38.3% increase in TL. During the taper phase, a 49.5% ...","downloadable_attachments":[{"id":74487865,"asset_id":61465373,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":69986673,"first_name":"Ciara","last_name":"O'Connor","domain_name":"limerick","page_name":"CiaraOConnor","display_name":"Ciara O'Connor","profile_url":"https://limerick.academia.edu/CiaraOConnor?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":6970,"name":"Biomarkers","url":"https://www.academia.edu/Documents/in/Biomarkers?f_ri=344106","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=344106","nofollow":true},{"id":28582,"name":"Swimming","url":"https://www.academia.edu/Documents/in/Swimming?f_ri=344106","nofollow":true},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=344106","nofollow":true},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":1201074,"name":"Psychological Stress","url":"https://www.academia.edu/Documents/in/Psychological_Stress?f_ri=344106"},{"id":1971458,"name":"Disabled Persons","url":"https://www.academia.edu/Documents/in/Disabled_Persons?f_ri=344106"},{"id":2483297,"name":"Immunoglobulin A","url":"https://www.academia.edu/Documents/in/Immunoglobulin_A?f_ri=344106"},{"id":2575892,"name":"Competitive Behavior ","url":"https://www.academia.edu/Documents/in/Competitive_Behavior?f_ri=344106"},{"id":3359206,"name":"hydrocortisone","url":"https://www.academia.edu/Documents/in/hydrocortisone?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_41070456" data-work_id="41070456" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/41070456/Efficient_Detection_of_Phthalate_Esters_in_Human_Saliva_via_Fluorescence_Spectroscopy">Efficient Detection of Phthalate Esters in Human Saliva via Fluorescence Spectroscopy</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The detection of phthalates in human biological fluids remains an important research objective because it provides an important measure of an individual’s exposure to this class of compounds, which have known deleterious health effects.... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_41070456" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The detection of phthalates in human biological fluids remains an important research objective because it provides an important measure of an individual’s exposure to this class of compounds, which have known deleterious health effects. Moreover, the ability to accomplish such detection in fluids that are easy to collect, such as saliva and urine, provides additional practical advantages. Reported herein is the application of cyclodextrin-promoted fluorescence energy transfer and<br />fluorescence modulation to accomplish precisely such detection: the development of sensitive and selective florescence-based detection methods for phthalates in saliva, an easily collectable human<br />biological fluid. Such saliva-based detection methods occur with high levels of selectivity (100 % differentiation) and sensitivity (limits of detection as low as 0.089 µM), and provide significant potential in the development of practical phthalate detection devices.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/41070456" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="9e9252ae26861bdf88fa33bd833dbdf4" rel="nofollow" data-download="{"attachment_id":61338362,"asset_id":41070456,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/61338362/download_file?st=MTc0MDAzODkzNCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="99511275" href="https://ariel.academia.edu/MindyLevine">Mindy Levine</a><script data-card-contents-for-user="99511275" type="text/json">{"id":99511275,"first_name":"Mindy","last_name":"Levine","domain_name":"ariel","page_name":"MindyLevine","display_name":"Mindy Levine","profile_url":"https://ariel.academia.edu/MindyLevine?f_ri=344106","photo":"https://0.academia-photos.com/99511275/24534455/31186881/s65_mindy.levine.jpg"}</script></span></span></li><li class="js-paper-rank-work_41070456 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="41070456"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 41070456, container: ".js-paper-rank-work_41070456", }); });</script></li><li class="js-percentile-work_41070456 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 41070456; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_41070456"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_41070456 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="41070456"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 41070456; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=41070456]").text(description); $(".js-view-count-work_41070456").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_41070456").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="41070456"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">3</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="1525" rel="nofollow" href="https://www.academia.edu/Documents/in/Fluorescence_Spectroscopy">Fluorescence Spectroscopy</a>, <script data-card-contents-for-ri="1525" type="text/json">{"id":1525,"name":"Fluorescence Spectroscopy","url":"https://www.academia.edu/Documents/in/Fluorescence_Spectroscopy?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="344106" rel="nofollow" href="https://www.academia.edu/Documents/in/Saliva">Saliva</a>, <script data-card-contents-for-ri="344106" type="text/json">{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="630539" rel="nofollow" href="https://www.academia.edu/Documents/in/Phthalates">Phthalates</a><script data-card-contents-for-ri="630539" type="text/json">{"id":630539,"name":"Phthalates","url":"https://www.academia.edu/Documents/in/Phthalates?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=41070456]'), work: {"id":41070456,"title":"Efficient Detection of Phthalate Esters in Human Saliva via Fluorescence Spectroscopy","created_at":"2019-11-25T23:32:08.538-08:00","url":"https://www.academia.edu/41070456/Efficient_Detection_of_Phthalate_Esters_in_Human_Saliva_via_Fluorescence_Spectroscopy?f_ri=344106","dom_id":"work_41070456","summary":"The detection of phthalates in human biological fluids remains an important research objective because it provides an important measure of an individual’s exposure to this class of compounds, which have known deleterious health effects. Moreover, the ability to accomplish such detection in fluids that are easy to collect, such as saliva and urine, provides additional practical advantages. Reported herein is the application of cyclodextrin-promoted fluorescence energy transfer and\nfluorescence modulation to accomplish precisely such detection: the development of sensitive and selective florescence-based detection methods for phthalates in saliva, an easily collectable human\nbiological fluid. Such saliva-based detection methods occur with high levels of selectivity (100 % differentiation) and sensitivity (limits of detection as low as 0.089 µM), and provide significant potential in the development of practical phthalate detection devices.","downloadable_attachments":[{"id":61338362,"asset_id":41070456,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":99511275,"first_name":"Mindy","last_name":"Levine","domain_name":"ariel","page_name":"MindyLevine","display_name":"Mindy Levine","profile_url":"https://ariel.academia.edu/MindyLevine?f_ri=344106","photo":"https://0.academia-photos.com/99511275/24534455/31186881/s65_mindy.levine.jpg"}],"research_interests":[{"id":1525,"name":"Fluorescence Spectroscopy","url":"https://www.academia.edu/Documents/in/Fluorescence_Spectroscopy?f_ri=344106","nofollow":true},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106","nofollow":true},{"id":630539,"name":"Phthalates","url":"https://www.academia.edu/Documents/in/Phthalates?f_ri=344106","nofollow":true}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_28620401" data-work_id="28620401" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/28620401/Changes_in_subgingival_microflora_and_humoral_immune_response_following_periodontal_therapy">Changes in subgingival microflora and humoral immune response following periodontal therapy</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">microflora and humoral immune response following periodontal therapy Darby IB, Mooney J, Kinane DF: Changes in subgingival microflora and humoral immune response following periodontal therapy. J Clin Periodontol 2001; 28: 796-805. C... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_28620401" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">microflora and humoral immune response following periodontal therapy Darby IB, Mooney J, Kinane DF: Changes in subgingival microflora and humoral immune response following periodontal therapy. J Clin Periodontol 2001; 28: 796-805. C Munksgaard, 2001.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/28620401" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="723acaa3ff05cb701827928acb4e8935" rel="nofollow" data-download="{"attachment_id":48985776,"asset_id":28620401,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48985776/download_file?st=MTc0MDAzODkzNCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="53698965" href="https://independent.academia.edu/DenisKinane">Denis Kinane</a><script data-card-contents-for-user="53698965" type="text/json">{"id":53698965,"first_name":"Denis","last_name":"Kinane","domain_name":"independent","page_name":"DenisKinane","display_name":"Denis Kinane","profile_url":"https://independent.academia.edu/DenisKinane?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_28620401 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="28620401"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 28620401, container: ".js-paper-rank-work_28620401", }); });</script></li><li class="js-percentile-work_28620401 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 28620401; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_28620401"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_28620401 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="28620401"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 28620401; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=28620401]").text(description); $(".js-view-count-work_28620401").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_28620401").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="28620401"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">7</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="596" rel="nofollow" href="https://www.academia.edu/Documents/in/Dentistry">Dentistry</a>, <script data-card-contents-for-ri="596" type="text/json">{"id":596,"name":"Dentistry","url":"https://www.academia.edu/Documents/in/Dentistry?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="12426" rel="nofollow" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a>, <script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="289271" rel="nofollow" href="https://www.academia.edu/Documents/in/Aged">Aged</a>, <script data-card-contents-for-ri="289271" type="text/json">{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="344106" rel="nofollow" href="https://www.academia.edu/Documents/in/Saliva">Saliva</a><script data-card-contents-for-ri="344106" type="text/json">{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=28620401]'), work: {"id":28620401,"title":"Changes in subgingival microflora and humoral immune response following periodontal therapy","created_at":"2016-09-20T05:21:47.773-07:00","url":"https://www.academia.edu/28620401/Changes_in_subgingival_microflora_and_humoral_immune_response_following_periodontal_therapy?f_ri=344106","dom_id":"work_28620401","summary":"microflora and humoral immune response following periodontal therapy Darby IB, Mooney J, Kinane DF: Changes in subgingival microflora and humoral immune response following periodontal therapy. J Clin Periodontol 2001; 28: 796-805. C Munksgaard, 2001.","downloadable_attachments":[{"id":48985776,"asset_id":28620401,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":53698965,"first_name":"Denis","last_name":"Kinane","domain_name":"independent","page_name":"DenisKinane","display_name":"Denis Kinane","profile_url":"https://independent.academia.edu/DenisKinane?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":596,"name":"Dentistry","url":"https://www.academia.edu/Documents/in/Dentistry?f_ri=344106","nofollow":true},{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=344106","nofollow":true},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=344106","nofollow":true},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106","nofollow":true},{"id":375098,"name":"Gingiva","url":"https://www.academia.edu/Documents/in/Gingiva?f_ri=344106"},{"id":552210,"name":"Periodontitis","url":"https://www.academia.edu/Documents/in/Periodontitis?f_ri=344106"},{"id":2139917,"name":"Dental Scaling","url":"https://www.academia.edu/Documents/in/Dental_Scaling?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_13327440 coauthored" data-work_id="13327440" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13327440/Rumination_and_Impaired_Cortisol_Recovery_Following_a_Social_Stressor_in_Adolescent_Depression">Rumination and Impaired Cortisol Recovery Following a Social Stressor in Adolescent Depression</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Response styles theory promotes rumination as a central cognitive construct driving negative mood and depression, and past research suggests that at least part of the mechanism driving rumination's depressogenic effect is through... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_13327440" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Response styles theory promotes rumination as a central cognitive construct driving negative mood and depression, and past research suggests that at least part of the mechanism driving rumination's depressogenic effect is through inhibiting the individual's ability to shift attentional focus away from negative environmental stimuli. In the current study, we hypothesized that high trait rumination would be associated with impaired recovery of the body's biological response to psychological stress. In a community sample of depressed (n=31) and non-depressed (n=33) adolescents we assessed rumination and the more adaptive trait of distraction and problem-solving with the Children's Response Styles Questionnaire (CRSQ; Abela 2000), and diagnostic status was confirmed using the Child and Adolescent Schedule of Affective Disorders and Schizophrenia (K-SADS; Kaufman et al. Journal of the American Academy of Child and Adolescent Psychiatry 36:980-988, 1997). Participants completed the Trier Social Stress Test (TSST; Kirschbaum et al. Neuropsychobiology 28:76-81, 1993), and the focus of our analyses was the change in salivary cortisol concentration between peak cortisol output (25 min post-stressor) and a sample taken during the "Recovery" period 65 minutes poststressor. Consistent with the predictions of response style theory, among the depressed adolescents only, high trait rumination was associated with delayed post-stressor cortisol recovery, whereas high trait distraction and problem-solving was associated with more rapid recovery. In contrast, response styles were not associated with cortisol recovery in the nondepressed group. These findings implicate impaired poststress cortisol recovery as a potential mechanism underlying the pathological effect of rumination on the development and maintenance of Major Depressive Disorder (MDD).</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13327440" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="33b1225cc41dc97a25870ee5fa70b9d4" rel="nofollow" data-download="{"attachment_id":45461965,"asset_id":13327440,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45461965/download_file?st=MTc0MDAzODkzNCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32700265" href="https://hms-harvard.academia.edu/JeremyStewart">Jeremy Stewart</a><script data-card-contents-for-user="32700265" type="text/json">{"id":32700265,"first_name":"Jeremy","last_name":"Stewart","domain_name":"hms-harvard","page_name":"JeremyStewart","display_name":"Jeremy Stewart","profile_url":"https://hms-harvard.academia.edu/JeremyStewart?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-13327440">+1</span><div class="hidden js-additional-users-13327440"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://queensu.academia.edu/KateHarkness">Kate Harkness</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-13327440'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-13327440').html(); 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In the current study, we hypothesized that high trait rumination would be associated with impaired recovery of the body's biological response to psychological stress. In a community sample of depressed (n=31) and non-depressed (n=33) adolescents we assessed rumination and the more adaptive trait of distraction and problem-solving with the Children's Response Styles Questionnaire (CRSQ; Abela 2000), and diagnostic status was confirmed using the Child and Adolescent Schedule of Affective Disorders and Schizophrenia (K-SADS; Kaufman et al. Journal of the American Academy of Child and Adolescent Psychiatry 36:980-988, 1997). Participants completed the Trier Social Stress Test (TSST; Kirschbaum et al. Neuropsychobiology 28:76-81, 1993), and the focus of our analyses was the change in salivary cortisol concentration between peak cortisol output (25 min post-stressor) and a sample taken during the \"Recovery\" period 65 minutes poststressor. Consistent with the predictions of response style theory, among the depressed adolescents only, high trait rumination was associated with delayed post-stressor cortisol recovery, whereas high trait distraction and problem-solving was associated with more rapid recovery. In contrast, response styles were not associated with cortisol recovery in the nondepressed group. These findings implicate impaired poststress cortisol recovery as a potential mechanism underlying the pathological effect of rumination on the development and maintenance of Major Depressive Disorder (MDD).","downloadable_attachments":[{"id":45461965,"asset_id":13327440,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32700265,"first_name":"Jeremy","last_name":"Stewart","domain_name":"hms-harvard","page_name":"JeremyStewart","display_name":"Jeremy Stewart","profile_url":"https://hms-harvard.academia.edu/JeremyStewart?f_ri=344106","photo":"/images/s65_no_pic.png"},{"id":32569898,"first_name":"Kate","last_name":"Harkness","domain_name":"queensu","page_name":"KateHarkness","display_name":"Kate Harkness","profile_url":"https://queensu.academia.edu/KateHarkness?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=344106","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=344106","nofollow":true},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=344106","nofollow":true},{"id":77794,"name":"Major Depressive Disorder","url":"https://www.academia.edu/Documents/in/Major_Depressive_Disorder?f_ri=344106","nofollow":true},{"id":123230,"name":"Regression Analysis","url":"https://www.academia.edu/Documents/in/Regression_Analysis?f_ri=344106"},{"id":192110,"name":"Ontario","url":"https://www.academia.edu/Documents/in/Ontario?f_ri=344106"},{"id":252761,"name":"Abnormal Child Psychology","url":"https://www.academia.edu/Documents/in/Abnormal_Child_Psychology?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":1819399,"name":"Case Control Studies","url":"https://www.academia.edu/Documents/in/Case_Control_Studies?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_15536577" data-work_id="15536577" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/15536577/Chemical_generation_of_nitric_oxide_in_the_mouth_from_the_enterosalivary_circulation_of_dietary_nitrate">Chemical generation of nitric oxide in the mouth from the enterosalivary circulation of dietary nitrate</a></div></div><div class="u-pb4x u-mt3x"></div><ul 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href="https://www.academia.edu/Documents/in/Microbiology">Microbiology</a>, <script data-card-contents-for-ri="159" type="text/json">{"id":159,"name":"Microbiology","url":"https://www.academia.edu/Documents/in/Microbiology?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="161" rel="nofollow" href="https://www.academia.edu/Documents/in/Neuroscience">Neuroscience</a>, <script data-card-contents-for-ri="161" type="text/json">{"id":161,"name":"Neuroscience","url":"https://www.academia.edu/Documents/in/Neuroscience?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="167" rel="nofollow" href="https://www.academia.edu/Documents/in/Physiology">Physiology</a>, <script data-card-contents-for-ri="167" type="text/json">{"id":167,"name":"Physiology","url":"https://www.academia.edu/Documents/in/Physiology?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="606" rel="nofollow" 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nitrate","created_at":"2015-09-09T02:15:19.220-07:00","url":"https://www.academia.edu/15536577/Chemical_generation_of_nitric_oxide_in_the_mouth_from_the_enterosalivary_circulation_of_dietary_nitrate?f_ri=344106","dom_id":"work_15536577","summary":null,"downloadable_attachments":[{"id":43111714,"asset_id":15536577,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":34692069,"first_name":"Carlo","last_name":"Leifert","domain_name":"newcastle","page_name":"CarloLeifert","display_name":"Carlo Leifert","profile_url":"https://newcastle.academia.edu/CarloLeifert?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":159,"name":"Microbiology","url":"https://www.academia.edu/Documents/in/Microbiology?f_ri=344106","nofollow":true},{"id":161,"name":"Neuroscience","url":"https://www.academia.edu/Documents/in/Neuroscience?f_ri=344106","nofollow":true},{"id":167,"name":"Physiology","url":"https://www.academia.edu/Documents/in/Physiology?f_ri=344106","nofollow":true},{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=344106","nofollow":true},{"id":623,"name":"Neurology","url":"https://www.academia.edu/Documents/in/Neurology?f_ri=344106"},{"id":626,"name":"Oncology","url":"https://www.academia.edu/Documents/in/Oncology?f_ri=344106"},{"id":1290,"name":"Immunology","url":"https://www.academia.edu/Documents/in/Immunology?f_ri=344106"},{"id":3642,"name":"Stem Cells","url":"https://www.academia.edu/Documents/in/Stem_Cells?f_ri=344106"},{"id":3770,"name":"Metabolism","url":"https://www.academia.edu/Documents/in/Metabolism?f_ri=344106"},{"id":5072,"name":"Molecular Medicine","url":"https://www.academia.edu/Documents/in/Molecular_Medicine?f_ri=344106"},{"id":6021,"name":"Cancer","url":"https://www.academia.edu/Documents/in/Cancer?f_ri=344106"},{"id":7043,"name":"Symbiosis","url":"https://www.academia.edu/Documents/in/Symbiosis?f_ri=344106"},{"id":8089,"name":"Virology","url":"https://www.academia.edu/Documents/in/Virology?f_ri=344106"},{"id":9478,"name":"Diet","url":"https://www.academia.edu/Documents/in/Diet?f_ri=344106"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=344106"},{"id":31632,"name":"Food Microbiology","url":"https://www.academia.edu/Documents/in/Food_Microbiology?f_ri=344106"},{"id":33319,"name":"Nature","url":"https://www.academia.edu/Documents/in/Nature?f_ri=344106"},{"id":93922,"name":"Nitric oxide","url":"https://www.academia.edu/Documents/in/Nitric_oxide?f_ri=344106"},{"id":122402,"name":"Nitrates","url":"https://www.academia.edu/Documents/in/Nitrates?f_ri=344106"},{"id":131495,"name":"Heart","url":"https://www.academia.edu/Documents/in/Heart?f_ri=344106"},{"id":166788,"name":"Nitrate Reductase","url":"https://www.academia.edu/Documents/in/Nitrate_Reductase?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":372397,"name":"Tongue","url":"https://www.academia.edu/Documents/in/Tongue?f_ri=344106"},{"id":375054,"name":"Rats","url":"https://www.academia.edu/Documents/in/Rats?f_ri=344106"},{"id":469032,"name":"Mouthwashes","url":"https://www.academia.edu/Documents/in/Mouthwashes?f_ri=344106"},{"id":528241,"name":"Biotransformation","url":"https://www.academia.edu/Documents/in/Biotransformation?f_ri=344106"},{"id":1030661,"name":"Stomach","url":"https://www.academia.edu/Documents/in/Stomach?f_ri=344106"},{"id":1137254,"name":"Hydrogen-Ion Concentration","url":"https://www.academia.edu/Documents/in/Hydrogen-Ion_Concentration?f_ri=344106"},{"id":1242098,"name":"Nitrosamines","url":"https://www.academia.edu/Documents/in/Nitrosamines?f_ri=344106"},{"id":1256747,"name":"Oxidation-Reduction","url":"https://www.academia.edu/Documents/in/Oxidation-Reduction?f_ri=344106"},{"id":1654024,"name":"Nitrites","url":"https://www.academia.edu/Documents/in/Nitrites?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_22311965 coauthored" data-work_id="22311965" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/22311965/Effects_of_saliva_contamination_on_resin_resin_bond_strength">Effects of saliva contamination on resin–resin bond strength</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objective. The purpose of this study is to evaluate the effects of saliva contamination on microtensile bond strength (mTBS) between resin interfaces and to determine which decontamination methods best re-established the original... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_22311965" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objective. The purpose of this study is to evaluate the effects of saliva contamination on microtensile bond strength (mTBS) between resin interfaces and to determine which decontamination methods best re-established the original resinresin bond strength.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/22311965" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="67eef0aace64898e712704a74970367c" rel="nofollow" data-download="{"attachment_id":42951227,"asset_id":22311965,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42951227/download_file?st=MTc0MDAzODkzNCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="43874754" href="https://independent.academia.edu/SigurdurEiriksson">Sigurdur Eiriksson</a><script data-card-contents-for-user="43874754" type="text/json">{"id":43874754,"first_name":"Sigurdur","last_name":"Eiriksson","domain_name":"independent","page_name":"SigurdurEiriksson","display_name":"Sigurdur Eiriksson","profile_url":"https://independent.academia.edu/SigurdurEiriksson?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-22311965">+1</span><div class="hidden js-additional-users-22311965"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/HaraldHeymann">Harald Heymann</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-22311965'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-22311965').html(); 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work-percentile"></span></span><script>$(function () { var workId = 31519192; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_31519192"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_31519192 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="31519192"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 31519192; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=31519192]").text(description); $(".js-view-count-work_31519192").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_31519192").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="31519192"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">14</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="428" rel="nofollow" href="https://www.academia.edu/Documents/in/Algorithms">Algorithms</a>, <script data-card-contents-for-ri="428" type="text/json">{"id":428,"name":"Algorithms","url":"https://www.academia.edu/Documents/in/Algorithms?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="57801" rel="nofollow" href="https://www.academia.edu/Documents/in/Dexamethasone">Dexamethasone</a>, <script data-card-contents-for-ri="57801" type="text/json">{"id":57801,"name":"Dexamethasone","url":"https://www.academia.edu/Documents/in/Dexamethasone?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="58431" rel="nofollow" href="https://www.academia.edu/Documents/in/Cortisol">Cortisol</a>, <script data-card-contents-for-ri="58431" type="text/json">{"id":58431,"name":"Cortisol","url":"https://www.academia.edu/Documents/in/Cortisol?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="81691" rel="nofollow" href="https://www.academia.edu/Documents/in/Posttraumatic_stress_disorder">Posttraumatic stress disorder</a><script data-card-contents-for-ri="81691" type="text/json">{"id":81691,"name":"Posttraumatic stress disorder","url":"https://www.academia.edu/Documents/in/Posttraumatic_stress_disorder?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=31519192]'), work: {"id":31519192,"title":"Cortisol response to acute trauma and risk of posttraumatic stress disorder","created_at":"2017-02-19T11:27:11.200-08:00","url":"https://www.academia.edu/31519192/Cortisol_response_to_acute_trauma_and_risk_of_posttraumatic_stress_disorder?f_ri=344106","dom_id":"work_31519192","summary":null,"downloadable_attachments":[{"id":51863040,"asset_id":31519192,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":18673222,"first_name":"Alexander","last_name":"McFarlane","domain_name":"adelaide","page_name":"AlexanderMcFarlane","display_name":"Alexander McFarlane","profile_url":"https://adelaide.academia.edu/AlexanderMcFarlane?f_ri=344106","photo":"https://0.academia-photos.com/18673222/140180564/129663861/s65_alexander.mcfarlane.png"}],"research_interests":[{"id":428,"name":"Algorithms","url":"https://www.academia.edu/Documents/in/Algorithms?f_ri=344106","nofollow":true},{"id":57801,"name":"Dexamethasone","url":"https://www.academia.edu/Documents/in/Dexamethasone?f_ri=344106","nofollow":true},{"id":58431,"name":"Cortisol","url":"https://www.academia.edu/Documents/in/Cortisol?f_ri=344106","nofollow":true},{"id":81691,"name":"Posttraumatic stress disorder","url":"https://www.academia.edu/Documents/in/Posttraumatic_stress_disorder?f_ri=344106","nofollow":true},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=344106"},{"id":133761,"name":"Psychoneuroendocrinology","url":"https://www.academia.edu/Documents/in/Psychoneuroendocrinology?f_ri=344106"},{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies?f_ri=344106"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=344106"},{"id":289330,"name":"Prevalence","url":"https://www.academia.edu/Documents/in/Prevalence?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=344106"},{"id":952182,"name":"Motor Vehicle Accident","url":"https://www.academia.edu/Documents/in/Motor_Vehicle_Accident?f_ri=344106"},{"id":1031658,"name":"Wounds and Injuries","url":"https://www.academia.edu/Documents/in/Wounds_and_Injuries?f_ri=344106"},{"id":1312754,"name":"Prospective Study","url":"https://www.academia.edu/Documents/in/Prospective_Study?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_79763188" data-work_id="79763188" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/79763188/Time_lag_between_peak_concentrations_of_plasma_and_salivary_cortisol_following_a_stressful_procedure_in_dairy_cattle">Time lag between peak concentrations of plasma and salivary cortisol following a stressful procedure in dairy cattle</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Measurement of salivary cortisol has been used extensively as a non-invasive alternative to blood sampling to assess adrenal activity in ruminants. However, there is evidence suggesting a considerable delay in the transfer of cortisol... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_79763188" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Measurement of salivary cortisol has been used extensively as a non-invasive alternative to blood sampling to assess adrenal activity in ruminants. However, there is evidence suggesting a considerable delay in the transfer of cortisol from plasma into saliva. Previous studies in cattle have used long sampling intervals making it difficult to characterise the relationship between plasma and salivary cortisol (PLCort and SACort, respectively) concentrations at different time points and determine whether or not such a time lag exist in large ruminants. Therefore, the objective of this study was to characterise the relationship between plasma and salivary cortisol and determine if there is a significant time lag between reaching peak cortisol concentrations in plasma and saliva across a 4.25 h time-period, using short sampling intervals of 10-15 min, following social separation in dairy cattle.Five cows were separated from their calves at 4 days after calving, and six calves were separa...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/79763188" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="f8de0b42d1f0080fd9a2876a9470333e" rel="nofollow" data-download="{"attachment_id":86369063,"asset_id":79763188,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/86369063/download_file?st=MTc0MDAzODkzNCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="57686841" href="https://independent.academia.edu/OrihuelaAgustin">Agustin Orihuela</a><script data-card-contents-for-user="57686841" type="text/json">{"id":57686841,"first_name":"Agustin","last_name":"Orihuela","domain_name":"independent","page_name":"OrihuelaAgustin","display_name":"Agustin Orihuela","profile_url":"https://independent.academia.edu/OrihuelaAgustin?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_79763188 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="79763188"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 79763188, container: ".js-paper-rank-work_79763188", }); });</script></li><li class="js-percentile-work_79763188 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 79763188; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_79763188"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_79763188 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="79763188"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 79763188; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=79763188]").text(description); $(".js-view-count-work_79763188").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_79763188").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="79763188"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">10</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="29980" rel="nofollow" href="https://www.academia.edu/Documents/in/Animal_Production">Animal Production</a>, <script data-card-contents-for-ri="29980" type="text/json">{"id":29980,"name":"Animal Production","url":"https://www.academia.edu/Documents/in/Animal_Production?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="137551" rel="nofollow" href="https://www.academia.edu/Documents/in/Social_Isolation">Social Isolation</a>, <script data-card-contents-for-ri="137551" type="text/json">{"id":137551,"name":"Social Isolation","url":"https://www.academia.edu/Documents/in/Social_Isolation?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="260829" rel="nofollow" href="https://www.academia.edu/Documents/in/Cattle">Cattle</a>, <script data-card-contents-for-ri="260829" type="text/json">{"id":260829,"name":"Cattle","url":"https://www.academia.edu/Documents/in/Cattle?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="344106" rel="nofollow" href="https://www.academia.edu/Documents/in/Saliva">Saliva</a><script data-card-contents-for-ri="344106" type="text/json">{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=79763188]'), work: {"id":79763188,"title":"Time lag between peak concentrations of plasma and salivary cortisol following a stressful procedure in dairy cattle","created_at":"2022-05-23T11:39:23.435-07:00","url":"https://www.academia.edu/79763188/Time_lag_between_peak_concentrations_of_plasma_and_salivary_cortisol_following_a_stressful_procedure_in_dairy_cattle?f_ri=344106","dom_id":"work_79763188","summary":"Measurement of salivary cortisol has been used extensively as a non-invasive alternative to blood sampling to assess adrenal activity in ruminants. However, there is evidence suggesting a considerable delay in the transfer of cortisol from plasma into saliva. Previous studies in cattle have used long sampling intervals making it difficult to characterise the relationship between plasma and salivary cortisol (PLCort and SACort, respectively) concentrations at different time points and determine whether or not such a time lag exist in large ruminants. Therefore, the objective of this study was to characterise the relationship between plasma and salivary cortisol and determine if there is a significant time lag between reaching peak cortisol concentrations in plasma and saliva across a 4.25 h time-period, using short sampling intervals of 10-15 min, following social separation in dairy cattle.Five cows were separated from their calves at 4 days after calving, and six calves were separa...","downloadable_attachments":[{"id":86369063,"asset_id":79763188,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":57686841,"first_name":"Agustin","last_name":"Orihuela","domain_name":"independent","page_name":"OrihuelaAgustin","display_name":"Agustin Orihuela","profile_url":"https://independent.academia.edu/OrihuelaAgustin?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":29980,"name":"Animal Production","url":"https://www.academia.edu/Documents/in/Animal_Production?f_ri=344106","nofollow":true},{"id":137551,"name":"Social Isolation","url":"https://www.academia.edu/Documents/in/Social_Isolation?f_ri=344106","nofollow":true},{"id":260829,"name":"Cattle","url":"https://www.academia.edu/Documents/in/Cattle?f_ri=344106","nofollow":true},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106","nofollow":true},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=344106"},{"id":568482,"name":"Biological markers","url":"https://www.academia.edu/Documents/in/Biological_markers?f_ri=344106"},{"id":644860,"name":"Veterinary Sciences","url":"https://www.academia.edu/Documents/in/Veterinary_Sciences?f_ri=344106"},{"id":722449,"name":"Physiological Stress Markers","url":"https://www.academia.edu/Documents/in/Physiological_Stress_Markers?f_ri=344106"},{"id":3359206,"name":"hydrocortisone","url":"https://www.academia.edu/Documents/in/hydrocortisone?f_ri=344106"},{"id":3647007,"name":"Stress Physiological","url":"https://www.academia.edu/Documents/in/Stress_Physiological?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_74258707" data-work_id="74258707" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/74258707/The_effects_of_race_related_stress_on_cortisol_reactivity_in_the_laboratory_implications_of_the_Duke_lacrosse_scandal">The effects of race-related stress on cortisol reactivity in the laboratory: implications of the Duke lacrosse scandal</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Background The experience of race-related stressors is associated with physiological stress responses. However, much is unknown still about the complex relationship between how race-related stressors are perceived and experienced and... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_74258707" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Background The experience of race-related stressors is associated with physiological stress responses. However, much is unknown still about the complex relationship between how race-related stressors are perceived and experienced and potential moderators such as strength of racial identity. Purpose This research examines the impact of a real-life stressor and strength of race identity on physiological responses to a social evaluative threat induced in the laboratory. Methods Salivary cortisol measures were collected throughout a stressor protocol. African-American participants were also randomized to one of two conditions designed to promote either racial identification or student identification, before the experimental task. Unexpectedly, a highly publicized real-life racial stressor, the Duke Lacrosse (LaX) scandal, occurred during the course of the data collection. This allowed for pre-post LaX comparisons to be made on cortisol levels. Results These comparisons showed that across both priming conditions, participants post-LaX had highly elevated cortisol levels that were nonresponsive to the experimental stress task, while their pre-LaX counterparts had lower cortisol levels that exhibited a normal stress response pattern. Furthermore, this effect of LaX was significantly moderated by gender, with women having lower mean cortisol levels pre-LaX but significantly greater cortisol levels than all other groups post-LaX. Conclusions These results suggest that recent exposure to race-related stress can have a sustained impact on physiological stress responses for African Americans.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/74258707" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="5643c4bae9e8a4a548576171a73792cc" rel="nofollow" data-download="{"attachment_id":82471641,"asset_id":74258707,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/82471641/download_file?st=MTc0MDAzODkzNCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="211601895" href="https://independent.academia.edu/RichmanLaura">Laura Richman</a><script data-card-contents-for-user="211601895" type="text/json">{"id":211601895,"first_name":"Laura","last_name":"Richman","domain_name":"independent","page_name":"RichmanLaura","display_name":"Laura Richman","profile_url":"https://independent.academia.edu/RichmanLaura?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_74258707 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="74258707"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 74258707, container: ".js-paper-rank-work_74258707", }); 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$(".js-view-count[data-work-id=74258707]").text(description); $(".js-view-count-work_74258707").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_74258707").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="74258707"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">16</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="922" rel="nofollow" href="https://www.academia.edu/Documents/in/Education">Education</a>, <script data-card-contents-for-ri="922" type="text/json">{"id":922,"name":"Education","url":"https://www.academia.edu/Documents/in/Education?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="5906" rel="nofollow" href="https://www.academia.edu/Documents/in/Prejudice">Prejudice</a>, <script data-card-contents-for-ri="5906" type="text/json">{"id":5906,"name":"Prejudice","url":"https://www.academia.edu/Documents/in/Prejudice?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a><script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=74258707]'), work: {"id":74258707,"title":"The effects of race-related stress on cortisol reactivity in the laboratory: implications of the Duke lacrosse scandal","created_at":"2022-03-21T18:07:31.482-07:00","url":"https://www.academia.edu/74258707/The_effects_of_race_related_stress_on_cortisol_reactivity_in_the_laboratory_implications_of_the_Duke_lacrosse_scandal?f_ri=344106","dom_id":"work_74258707","summary":"Background The experience of race-related stressors is associated with physiological stress responses. However, much is unknown still about the complex relationship between how race-related stressors are perceived and experienced and potential moderators such as strength of racial identity. Purpose This research examines the impact of a real-life stressor and strength of race identity on physiological responses to a social evaluative threat induced in the laboratory. Methods Salivary cortisol measures were collected throughout a stressor protocol. African-American participants were also randomized to one of two conditions designed to promote either racial identification or student identification, before the experimental task. Unexpectedly, a highly publicized real-life racial stressor, the Duke Lacrosse (LaX) scandal, occurred during the course of the data collection. This allowed for pre-post LaX comparisons to be made on cortisol levels. Results These comparisons showed that across both priming conditions, participants post-LaX had highly elevated cortisol levels that were nonresponsive to the experimental stress task, while their pre-LaX counterparts had lower cortisol levels that exhibited a normal stress response pattern. Furthermore, this effect of LaX was significantly moderated by gender, with women having lower mean cortisol levels pre-LaX but significantly greater cortisol levels than all other groups post-LaX. Conclusions These results suggest that recent exposure to race-related stress can have a sustained impact on physiological stress responses for African Americans.","downloadable_attachments":[{"id":82471641,"asset_id":74258707,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":211601895,"first_name":"Laura","last_name":"Richman","domain_name":"independent","page_name":"RichmanLaura","display_name":"Laura Richman","profile_url":"https://independent.academia.edu/RichmanLaura?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=344106","nofollow":true},{"id":922,"name":"Education","url":"https://www.academia.edu/Documents/in/Education?f_ri=344106","nofollow":true},{"id":5906,"name":"Prejudice","url":"https://www.academia.edu/Documents/in/Prejudice?f_ri=344106","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=344106","nofollow":true},{"id":58431,"name":"Cortisol","url":"https://www.academia.edu/Documents/in/Cortisol?f_ri=344106"},{"id":68342,"name":"African American","url":"https://www.academia.edu/Documents/in/African_American?f_ri=344106"},{"id":153168,"name":"Data Collection","url":"https://www.academia.edu/Documents/in/Data_Collection?f_ri=344106"},{"id":219123,"name":"Ethnic Groups","url":"https://www.academia.edu/Documents/in/Ethnic_Groups?f_ri=344106"},{"id":224603,"name":"Physiological Response","url":"https://www.academia.edu/Documents/in/Physiological_Response?f_ri=344106"},{"id":233800,"name":"African Americans","url":"https://www.academia.edu/Documents/in/African_Americans?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":976842,"name":"Salivary Cortisol","url":"https://www.academia.edu/Documents/in/Salivary_Cortisol?f_ri=344106"},{"id":1000427,"name":"Reference Values","url":"https://www.academia.edu/Documents/in/Reference_Values?f_ri=344106"},{"id":2922956,"name":"Psychology and Cognitive Sciences","url":"https://www.academia.edu/Documents/in/Psychology_and_Cognitive_Sciences?f_ri=344106"},{"id":3359206,"name":"hydrocortisone","url":"https://www.academia.edu/Documents/in/hydrocortisone?f_ri=344106"},{"id":3763225,"name":"Medical and Health Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_72825949" data-work_id="72825949" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/72825949/LC_MS_MS_method_for_the_determination_of_nine_antidepressants_and_some_of_their_main_metabolites_in_oral_fluid_and_plasma">LC–MS/MS method for the determination of nine antidepressants and some of their main metabolites in oral fluid and plasma</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">In this paper, a fast, sensitive and selective LC-MS/MS method is described for the simultaneous determination of amitriptyline, imipramine, clomipramine, fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram and venlafaxine, as... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_72825949" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">In this paper, a fast, sensitive and selective LC-MS/MS method is described for the simultaneous determination of amitriptyline, imipramine, clomipramine, fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram and venlafaxine, as well as some of their main metabolites (nortriptyline, desipramine, norclomipramine and norfluoxetine), in oral fluid and plasma. The sample (0.2 mL) was extracted with an automated solid-phase extraction system (ASPEC XL), using mixed mode OASIS MCX cartridges. Chromatographic separation was performed in a Sunfire C18 IS column (20 mm × 2.1 mm, 3.5 m), using a gradient of acetonitrile and ammonium formate (pH 3; 2 mM) as mobile phase, which allowed the elution of all the compounds in less than 5 min. The method has been fully validated in both specimens. This method was initially applied to the analysis of oral fluid and plasma samples from patients on antidepressant treatment in order to assess for which compounds it was likely to find a good correlation between both matrices. The best results were obtained for venlafaxine, so the study was extended for this compound, comparing the ratio between oral fluid and plasma concentrations (R OF/PL) in five patients on venlafaxine treatment when both samples were collected simultaneously on four different occasions. An important inter and intraindividual variability was found in oral fluid concentrations for 150 mg dose (mean = 287.5 ng/m, range 58.8-531.2 ng/mL) and for 75 mg dose (mean = 186.3 ng/mL, range = 82.1-289.2 ng/mL). R OF/PL was calculated for each patient on the four different occasions, showing also a high variability (CV = 24.2-69.6%).</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/72825949" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="229741558f4d8b6e6ab0fa754e2fdb05" rel="nofollow" data-download="{"attachment_id":81597513,"asset_id":72825949,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/81597513/download_file?st=MTc0MDAzODkzNCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="39217332" href="https://independent.academia.edu/ML%C3%B3pezrivadulla">M. López-rivadulla</a><script data-card-contents-for-user="39217332" type="text/json">{"id":39217332,"first_name":"M.","last_name":"López-rivadulla","domain_name":"independent","page_name":"MLópezrivadulla","display_name":"M. López-rivadulla","profile_url":"https://independent.academia.edu/ML%C3%B3pezrivadulla?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_72825949 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="72825949"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 72825949, container: ".js-paper-rank-work_72825949", }); });</script></li><li class="js-percentile-work_72825949 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 72825949; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_72825949"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_72825949 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="72825949"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 72825949; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=72825949]").text(description); $(".js-view-count-work_72825949").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_72825949").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="72825949"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">17</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="523" rel="nofollow" href="https://www.academia.edu/Documents/in/Chemistry">Chemistry</a>, <script data-card-contents-for-ri="523" type="text/json">{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="524" rel="nofollow" href="https://www.academia.edu/Documents/in/Analytical_Chemistry">Analytical Chemistry</a>, <script data-card-contents-for-ri="524" type="text/json">{"id":524,"name":"Analytical Chemistry","url":"https://www.academia.edu/Documents/in/Analytical_Chemistry?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="37434" rel="nofollow" href="https://www.academia.edu/Documents/in/Quantitative_analysis">Quantitative analysis</a><script data-card-contents-for-ri="37434" type="text/json">{"id":37434,"name":"Quantitative analysis","url":"https://www.academia.edu/Documents/in/Quantitative_analysis?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=72825949]'), work: {"id":72825949,"title":"LC–MS/MS method for the determination of nine antidepressants and some of their main metabolites in oral fluid and plasma","created_at":"2022-03-02T11:55:32.075-08:00","url":"https://www.academia.edu/72825949/LC_MS_MS_method_for_the_determination_of_nine_antidepressants_and_some_of_their_main_metabolites_in_oral_fluid_and_plasma?f_ri=344106","dom_id":"work_72825949","summary":"In this paper, a fast, sensitive and selective LC-MS/MS method is described for the simultaneous determination of amitriptyline, imipramine, clomipramine, fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram and venlafaxine, as well as some of their main metabolites (nortriptyline, desipramine, norclomipramine and norfluoxetine), in oral fluid and plasma. The sample (0.2 mL) was extracted with an automated solid-phase extraction system (ASPEC XL), using mixed mode OASIS MCX cartridges. Chromatographic separation was performed in a Sunfire C18 IS column (20 mm × 2.1 mm, 3.5 m), using a gradient of acetonitrile and ammonium formate (pH 3; 2 mM) as mobile phase, which allowed the elution of all the compounds in less than 5 min. The method has been fully validated in both specimens. This method was initially applied to the analysis of oral fluid and plasma samples from patients on antidepressant treatment in order to assess for which compounds it was likely to find a good correlation between both matrices. The best results were obtained for venlafaxine, so the study was extended for this compound, comparing the ratio between oral fluid and plasma concentrations (R OF/PL) in five patients on venlafaxine treatment when both samples were collected simultaneously on four different occasions. An important inter and intraindividual variability was found in oral fluid concentrations for 150 mg dose (mean = 287.5 ng/m, range 58.8-531.2 ng/mL) and for 75 mg dose (mean = 186.3 ng/mL, range = 82.1-289.2 ng/mL). R OF/PL was calculated for each patient on the four different occasions, showing also a high variability (CV = 24.2-69.6%).","downloadable_attachments":[{"id":81597513,"asset_id":72825949,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":39217332,"first_name":"M.","last_name":"López-rivadulla","domain_name":"independent","page_name":"MLópezrivadulla","display_name":"M. López-rivadulla","profile_url":"https://independent.academia.edu/ML%C3%B3pezrivadulla?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry?f_ri=344106","nofollow":true},{"id":524,"name":"Analytical Chemistry","url":"https://www.academia.edu/Documents/in/Analytical_Chemistry?f_ri=344106","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=344106","nofollow":true},{"id":37434,"name":"Quantitative analysis","url":"https://www.academia.edu/Documents/in/Quantitative_analysis?f_ri=344106","nofollow":true},{"id":81504,"name":"Correlation","url":"https://www.academia.edu/Documents/in/Correlation?f_ri=344106"},{"id":83426,"name":"Solid Phase Extraction","url":"https://www.academia.edu/Documents/in/Solid_Phase_Extraction?f_ri=344106"},{"id":117555,"name":"Plasma","url":"https://www.academia.edu/Documents/in/Plasma?f_ri=344106"},{"id":134372,"name":"Mixed Mode","url":"https://www.academia.edu/Documents/in/Mixed_Mode?f_ri=344106"},{"id":163275,"name":"Tandem Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Tandem_Mass_Spectrometry?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":398287,"name":"Liquid Chromatography","url":"https://www.academia.edu/Documents/in/Liquid_Chromatography?f_ri=344106"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=344106"},{"id":549280,"name":"Reproducibility of Results","url":"https://www.academia.edu/Documents/in/Reproducibility_of_Results?f_ri=344106"},{"id":641216,"name":"Quantitative Analysis","url":"https://www.academia.edu/Documents/in/Quantitative_Analysis-1?f_ri=344106"},{"id":901876,"name":"Sensitivity and Specificity","url":"https://www.academia.edu/Documents/in/Sensitivity_and_Specificity?f_ri=344106"},{"id":3789884,"name":"Pharmacology and pharmaceutical sciences","url":"https://www.academia.edu/Documents/in/Pharmacology_and_pharmaceutical_sciences?f_ri=344106"},{"id":3988408,"name":"Antidepressive agents","url":"https://www.academia.edu/Documents/in/Antidepressive_agents?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_52356012" data-work_id="52356012" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/52356012/Validation_of_deuterium_and_oxygen_18_in_urine_and_saliva_samples_from_children_using_on_line_continuous_flow_isotope_ratio_mass_spectrometry">Validation of deuterium and oxygen 18 in urine and saliva samples from children using on-line continuous-flow isotope ratio mass spectrometry</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The doubly labelled water method is valuable for measuring energy expenditure in humans. It usually involves blood or urine sampling, which might be difficult in neonates and children with cerebral palsy or other disabilities. We... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_52356012" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The doubly labelled water method is valuable for measuring energy expenditure in humans. It usually involves blood or urine sampling, which might be difficult in neonates and children with cerebral palsy or other disabilities. We therefore aimed to validate a method making use of saliva samples analyzed by automated thermal conversion elemental analyzer in combination with isotope ratio mass spectrometry (TC-EA/IRMS). The subjects received labelled water orally and urine and saliva samples were collected and analyzed. Deuterium as well as oxygen 18 was measured in one single run using a peak jump method. Excellent linearity was found for measurement of enrichments of deuterium (R 2 ¼ 0.9999) and oxygen 18 (R 2 ¼ 0.9999). The intra-assay precision and the inter-assay precision of the measurement of two standards were good for both deuterium and oxygen 18. The variation between urine and saliva samples was small (4.83% for deuterium and 2.33% for oxygen 18 n ¼ 40). Saliva sampling is to be preferred, therefore, as it can be easily collected and is non-invasive. Moreover, its time of production is almost exactly known. The TC-EA/IRMS method is a good alternative to the more laborious off-line IRMS measurements.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/52356012" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="f3e224b6c42e62db453764981a0ae290" rel="nofollow" data-download="{"attachment_id":69658563,"asset_id":52356012,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/69658563/download_file?st=MTc0MDAzODkzNCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="81448714" href="https://virginis.academia.edu/HenkSchierbeek">Henk Schierbeek</a><script data-card-contents-for-user="81448714" type="text/json">{"id":81448714,"first_name":"Henk","last_name":"Schierbeek","domain_name":"virginis","page_name":"HenkSchierbeek","display_name":"Henk Schierbeek","profile_url":"https://virginis.academia.edu/HenkSchierbeek?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_52356012 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="52356012"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 52356012, container: ".js-paper-rank-work_52356012", }); });</script></li><li class="js-percentile-work_52356012 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 52356012; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_52356012"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_52356012 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="52356012"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 52356012; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=52356012]").text(description); $(".js-view-count-work_52356012").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_52356012").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="52356012"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">14</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="400" rel="nofollow" href="https://www.academia.edu/Documents/in/Earth_Sciences">Earth Sciences</a>, <script data-card-contents-for-ri="400" type="text/json">{"id":400,"name":"Earth Sciences","url":"https://www.academia.edu/Documents/in/Earth_Sciences?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="5769" rel="nofollow" href="https://www.academia.edu/Documents/in/Mass_Spectrometry">Mass Spectrometry</a>, <script data-card-contents-for-ri="5769" type="text/json">{"id":5769,"name":"Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Mass_Spectrometry?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="12971" rel="nofollow" href="https://www.academia.edu/Documents/in/Isotope_Ratio_Mass_Spectrometry">Isotope Ratio Mass Spectrometry</a>, <script data-card-contents-for-ri="12971" type="text/json">{"id":12971,"name":"Isotope Ratio Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Isotope_Ratio_Mass_Spectrometry?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a><script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=52356012]'), work: {"id":52356012,"title":"Validation of deuterium and oxygen 18 in urine and saliva samples from children using on-line continuous-flow isotope ratio mass spectrometry","created_at":"2021-09-14T14:35:47.721-07:00","url":"https://www.academia.edu/52356012/Validation_of_deuterium_and_oxygen_18_in_urine_and_saliva_samples_from_children_using_on_line_continuous_flow_isotope_ratio_mass_spectrometry?f_ri=344106","dom_id":"work_52356012","summary":"The doubly labelled water method is valuable for measuring energy expenditure in humans. It usually involves blood or urine sampling, which might be difficult in neonates and children with cerebral palsy or other disabilities. We therefore aimed to validate a method making use of saliva samples analyzed by automated thermal conversion elemental analyzer in combination with isotope ratio mass spectrometry (TC-EA/IRMS). The subjects received labelled water orally and urine and saliva samples were collected and analyzed. Deuterium as well as oxygen 18 was measured in one single run using a peak jump method. Excellent linearity was found for measurement of enrichments of deuterium (R 2 ¼ 0.9999) and oxygen 18 (R 2 ¼ 0.9999). The intra-assay precision and the inter-assay precision of the measurement of two standards were good for both deuterium and oxygen 18. The variation between urine and saliva samples was small (4.83% for deuterium and 2.33% for oxygen 18 n ¼ 40). Saliva sampling is to be preferred, therefore, as it can be easily collected and is non-invasive. Moreover, its time of production is almost exactly known. The TC-EA/IRMS method is a good alternative to the more laborious off-line IRMS measurements.","downloadable_attachments":[{"id":69658563,"asset_id":52356012,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":81448714,"first_name":"Henk","last_name":"Schierbeek","domain_name":"virginis","page_name":"HenkSchierbeek","display_name":"Henk Schierbeek","profile_url":"https://virginis.academia.edu/HenkSchierbeek?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":400,"name":"Earth Sciences","url":"https://www.academia.edu/Documents/in/Earth_Sciences?f_ri=344106","nofollow":true},{"id":5769,"name":"Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Mass_Spectrometry?f_ri=344106","nofollow":true},{"id":12971,"name":"Isotope Ratio Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Isotope_Ratio_Mass_Spectrometry?f_ri=344106","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=344106","nofollow":true},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=344106"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=344106"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=344106"},{"id":143483,"name":"Deuterium","url":"https://www.academia.edu/Documents/in/Deuterium?f_ri=344106"},{"id":230701,"name":"Oxygen Isotopes","url":"https://www.academia.edu/Documents/in/Oxygen_Isotopes?f_ri=344106"},{"id":260118,"name":"CHEMICAL SCIENCES","url":"https://www.academia.edu/Documents/in/CHEMICAL_SCIENCES?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":417933,"name":"Continuous Flow","url":"https://www.academia.edu/Documents/in/Continuous_Flow?f_ri=344106"},{"id":1485193,"name":"Rapid","url":"https://www.academia.edu/Documents/in/Rapid?f_ri=344106"},{"id":2489700,"name":"Child preschool","url":"https://www.academia.edu/Documents/in/Child_preschool?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_31063961" data-work_id="31063961" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/31063961/Comparison_of_oral_findings_in_special_needs_children_with_and_without_gastrostomy">Comparison of oral findings in special needs children with and without gastrostomy</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The objective of this study was to compare aspiration pneumonia (AP)-associated microflora, calculus, and oral hygiene/care seeking behaviors in special health care needs children (SC) with gastrostomy (GT) and without. Methods:... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_31063961" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The objective of this study was to compare aspiration pneumonia (AP)-associated microflora, calculus, and oral hygiene/care seeking behaviors in special health care needs children (SC) with gastrostomy (GT) and without. Methods: Twenty-seven GT SC, ages 3 to 12 years old and matched for age and gender with 27 non-GT SC, were examined by 2 trained investigators who recorded calculus and gingival inflammation and reconciled differences. Plaque was obtained using preweighed dry paper points and saliva sampled using sterile pipettes and cultured using standard bioassay procedures in a hospital laboratory. Parent/caretakers completed a medical and oral health questionnaire. Results: No significant differences were noted for age, gender, weight, primary diagnosis, vomiting, constipation, or swallowing disorder, but GT children received 4 medications vs 1 for non-GT and were significantly more likely to have had AP, need special feeding, and drool (P≤.05). Oral health measures were not significantly different for brushing frequency, dentifrice use, brushing problems, frequency of dental care, or gingival inflammation, but GT patients had significantly more plaque and calculus. GT patients had significantly more Haemophilus influenzae, with trends toward more gram negative enteric rods, pseudomonas, and Streptococcus pneumoniae and higher concentrations in several GT-patients and little or none in non-GT patients. GT SC had significantly less β-streptococci than non-GT patients (P≤.05). Conclusions: GT SC had significantly more of 1 AP-associated organism than non-GT SC and significantly more calculus and plaque, in spite of similar care seeking and hygiene behaviors. (Pediatr Dent. 2004;26:283-288)</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/31063961" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="179ee19ad3dacd58611b2af85c247f39" rel="nofollow" data-download="{"attachment_id":51498204,"asset_id":31063961,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/51498204/download_file?st=MTc0MDAzODkzNCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="59240984" href="https://independent.academia.edu/PaulCasamassimo">Paul Casamassimo</a><script data-card-contents-for-user="59240984" type="text/json">{"id":59240984,"first_name":"Paul","last_name":"Casamassimo","domain_name":"independent","page_name":"PaulCasamassimo","display_name":"Paul Casamassimo","profile_url":"https://independent.academia.edu/PaulCasamassimo?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_31063961 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="31063961"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 31063961, container: ".js-paper-rank-work_31063961", }); });</script></li><li class="js-percentile-work_31063961 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 31063961; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_31063961"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_31063961 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="31063961"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 31063961; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=31063961]").text(description); $(".js-view-count-work_31063961").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_31063961").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="31063961"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">25</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="596" rel="nofollow" href="https://www.academia.edu/Documents/in/Dentistry">Dentistry</a>, <script data-card-contents-for-ri="596" type="text/json">{"id":596,"name":"Dentistry","url":"https://www.academia.edu/Documents/in/Dentistry?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4441" rel="nofollow" href="https://www.academia.edu/Documents/in/Health_Care">Health Care</a>, <script data-card-contents-for-ri="4441" type="text/json">{"id":4441,"name":"Health Care","url":"https://www.academia.edu/Documents/in/Health_Care?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="28920" rel="nofollow" href="https://www.academia.edu/Documents/in/Streptococcus_pneumoniae">Streptococcus pneumoniae</a>, <script data-card-contents-for-ri="28920" type="text/json">{"id":28920,"name":"Streptococcus pneumoniae","url":"https://www.academia.edu/Documents/in/Streptococcus_pneumoniae?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="64933" rel="nofollow" href="https://www.academia.edu/Documents/in/Child">Child</a><script data-card-contents-for-ri="64933" type="text/json">{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=31063961]'), work: {"id":31063961,"title":"Comparison of oral findings in special needs children with and without gastrostomy","created_at":"2017-01-24T12:19:15.898-08:00","url":"https://www.academia.edu/31063961/Comparison_of_oral_findings_in_special_needs_children_with_and_without_gastrostomy?f_ri=344106","dom_id":"work_31063961","summary":"The objective of this study was to compare aspiration pneumonia (AP)-associated microflora, calculus, and oral hygiene/care seeking behaviors in special health care needs children (SC) with gastrostomy (GT) and without. Methods: Twenty-seven GT SC, ages 3 to 12 years old and matched for age and gender with 27 non-GT SC, were examined by 2 trained investigators who recorded calculus and gingival inflammation and reconciled differences. Plaque was obtained using preweighed dry paper points and saliva sampled using sterile pipettes and cultured using standard bioassay procedures in a hospital laboratory. Parent/caretakers completed a medical and oral health questionnaire. Results: No significant differences were noted for age, gender, weight, primary diagnosis, vomiting, constipation, or swallowing disorder, but GT children received 4 medications vs 1 for non-GT and were significantly more likely to have had AP, need special feeding, and drool (P≤.05). Oral health measures were not significantly different for brushing frequency, dentifrice use, brushing problems, frequency of dental care, or gingival inflammation, but GT patients had significantly more plaque and calculus. GT patients had significantly more Haemophilus influenzae, with trends toward more gram negative enteric rods, pseudomonas, and Streptococcus pneumoniae and higher concentrations in several GT-patients and little or none in non-GT patients. GT SC had significantly less β-streptococci than non-GT patients (P≤.05). Conclusions: GT SC had significantly more of 1 AP-associated organism than non-GT SC and significantly more calculus and plaque, in spite of similar care seeking and hygiene behaviors. (Pediatr Dent. 2004;26:283-288)","downloadable_attachments":[{"id":51498204,"asset_id":31063961,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":59240984,"first_name":"Paul","last_name":"Casamassimo","domain_name":"independent","page_name":"PaulCasamassimo","display_name":"Paul Casamassimo","profile_url":"https://independent.academia.edu/PaulCasamassimo?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":596,"name":"Dentistry","url":"https://www.academia.edu/Documents/in/Dentistry?f_ri=344106","nofollow":true},{"id":4441,"name":"Health Care","url":"https://www.academia.edu/Documents/in/Health_Care?f_ri=344106","nofollow":true},{"id":28920,"name":"Streptococcus pneumoniae","url":"https://www.academia.edu/Documents/in/Streptococcus_pneumoniae?f_ri=344106","nofollow":true},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=344106","nofollow":true},{"id":77677,"name":"Oral health","url":"https://www.academia.edu/Documents/in/Oral_health?f_ri=344106"},{"id":177876,"name":"Sterilization","url":"https://www.academia.edu/Documents/in/Sterilization?f_ri=344106"},{"id":189576,"name":"Pediatric","url":"https://www.academia.edu/Documents/in/Pediatric?f_ri=344106"},{"id":277912,"name":"Special Needs","url":"https://www.academia.edu/Documents/in/Special_Needs?f_ri=344106"},{"id":295705,"name":"Pediatric dentistry","url":"https://www.academia.edu/Documents/in/Pediatric_dentistry?f_ri=344106"},{"id":335965,"name":"Gram-negative bacteria","url":"https://www.academia.edu/Documents/in/Gram-negative_bacteria?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":371994,"name":"Dental Calculus","url":"https://www.academia.edu/Documents/in/Dental_Calculus?f_ri=344106"},{"id":375293,"name":"Mouth Diseases","url":"https://www.academia.edu/Documents/in/Mouth_Diseases?f_ri=344106"},{"id":419881,"name":"Oral Hygiene","url":"https://www.academia.edu/Documents/in/Oral_Hygiene?f_ri=344106"},{"id":469110,"name":"Dental Care","url":"https://www.academia.edu/Documents/in/Dental_Care?f_ri=344106"},{"id":469114,"name":"Tooth Diseases","url":"https://www.academia.edu/Documents/in/Tooth_Diseases?f_ri=344106"},{"id":477952,"name":"Dental Plaque","url":"https://www.academia.edu/Documents/in/Dental_Plaque?f_ri=344106"},{"id":555323,"name":"Drug Therapy","url":"https://www.academia.edu/Documents/in/Drug_Therapy?f_ri=344106"},{"id":627219,"name":"Pediatric Dentistry","url":"https://www.academia.edu/Documents/in/Pediatric_Dentistry-1?f_ri=344106"},{"id":869579,"name":"Gastrostomy","url":"https://www.academia.edu/Documents/in/Gastrostomy?f_ri=344106"},{"id":1426584,"name":"Gingivitis","url":"https://www.academia.edu/Documents/in/Gingivitis?f_ri=344106"},{"id":1533489,"name":"Haemophilus Infections Market","url":"https://www.academia.edu/Documents/in/Haemophilus_Infections_Market?f_ri=344106"},{"id":1819399,"name":"Case Control Studies","url":"https://www.academia.edu/Documents/in/Case_Control_Studies?f_ri=344106"},{"id":1990998,"name":"Haemophilus influenzae","url":"https://www.academia.edu/Documents/in/Haemophilus_influenzae?f_ri=344106"},{"id":2489700,"name":"Child preschool","url":"https://www.academia.edu/Documents/in/Child_preschool?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_8831679" data-work_id="8831679" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/8831679/Salivary_testosterone_does_not_predict_mental_rotation_performance_in_men_or_women">Salivary testosterone does not predict mental rotation performance in men or women</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Multiple studies report relationships between circulating androgens and performance on sexually differentiated spatial cognitive tasks in human adults, yet other studies find no such relationships. Relatively small sample sizes are a... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_8831679" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Multiple studies report relationships between circulating androgens and performance on sexually differentiated spatial cognitive tasks in human adults, yet other studies find no such relationships. Relatively small sample sizes are a likely source of some of these discrepancies. The present study thus tests for activational effects of testosterone (T) using a within-participants design by examining relationships between diurnal fluctuations in salivary T and performance on a male-biased spatial cognitive task (Mental Rotation Task) in the largest sample yet collected: 160 women and 177 men. T concentrations were unrelated to within-sex variation in mental rotation performance in both sexes. Further, between-session learning-related changes in performance were unrelated to T levels, and circadian changes in T were unrelated to changes in spatial performance in either sex. These results suggest that circulating T does not contribute substantially to sex differences in spatial ability in young men and women. By elimination, the contribution of androgens to sex differences in human performance on these tasks may be limited to earlier, organizational periods.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/8831679" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="4696d8cad342a727f4aba030750003ac" rel="nofollow" data-download="{"attachment_id":47987642,"asset_id":8831679,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/47987642/download_file?st=MTc0MDAzODkzNCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="19212105" href="https://independent.academia.edu/CynthiaC%C3%A1rdenas">Cynthia Cárdenas</a><script data-card-contents-for-user="19212105" type="text/json">{"id":19212105,"first_name":"Cynthia","last_name":"Cárdenas","domain_name":"independent","page_name":"CynthiaCárdenas","display_name":"Cynthia Cárdenas","profile_url":"https://independent.academia.edu/CynthiaC%C3%A1rdenas?f_ri=344106","photo":"https://0.academia-photos.com/19212105/8840201/9868929/s65_cynthia.c_rdenas.jpg_oh_d30712930eb40d038e394f59ae95c3c8_oe_55e5109b___gda___1439498506_559f47722dec05bf375a24222e9bd59a"}</script></span></span></li><li class="js-paper-rank-work_8831679 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="8831679"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 8831679, container: ".js-paper-rank-work_8831679", }); 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$(".js-view-count[data-work-id=8831679]").text(description); $(".js-view-count-work_8831679").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_8831679").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="8831679"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">22</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="2599" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychometrics">Psychometrics</a>, <script data-card-contents-for-ri="2599" type="text/json">{"id":2599,"name":"Psychometrics","url":"https://www.academia.edu/Documents/in/Psychometrics?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="2973" rel="nofollow" href="https://www.academia.edu/Documents/in/Spatial_cognition">Spatial cognition</a>, <script data-card-contents-for-ri="2973" type="text/json">{"id":2973,"name":"Spatial cognition","url":"https://www.academia.edu/Documents/in/Spatial_cognition?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4212" rel="nofollow" href="https://www.academia.edu/Documents/in/Cognition">Cognition</a>, <script data-card-contents-for-ri="4212" type="text/json">{"id":4212,"name":"Cognition","url":"https://www.academia.edu/Documents/in/Cognition?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="9043" rel="nofollow" href="https://www.academia.edu/Documents/in/Performance">Performance</a><script data-card-contents-for-ri="9043" type="text/json">{"id":9043,"name":"Performance","url":"https://www.academia.edu/Documents/in/Performance?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=8831679]'), work: {"id":8831679,"title":"Salivary testosterone does not predict mental rotation performance in men or women","created_at":"2014-10-17T12:52:57.378-07:00","url":"https://www.academia.edu/8831679/Salivary_testosterone_does_not_predict_mental_rotation_performance_in_men_or_women?f_ri=344106","dom_id":"work_8831679","summary":"Multiple studies report relationships between circulating androgens and performance on sexually differentiated spatial cognitive tasks in human adults, yet other studies find no such relationships. Relatively small sample sizes are a likely source of some of these discrepancies. The present study thus tests for activational effects of testosterone (T) using a within-participants design by examining relationships between diurnal fluctuations in salivary T and performance on a male-biased spatial cognitive task (Mental Rotation Task) in the largest sample yet collected: 160 women and 177 men. T concentrations were unrelated to within-sex variation in mental rotation performance in both sexes. Further, between-session learning-related changes in performance were unrelated to T levels, and circadian changes in T were unrelated to changes in spatial performance in either sex. These results suggest that circulating T does not contribute substantially to sex differences in spatial ability in young men and women. By elimination, the contribution of androgens to sex differences in human performance on these tasks may be limited to earlier, organizational periods.","downloadable_attachments":[{"id":47987642,"asset_id":8831679,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":19212105,"first_name":"Cynthia","last_name":"Cárdenas","domain_name":"independent","page_name":"CynthiaCárdenas","display_name":"Cynthia Cárdenas","profile_url":"https://independent.academia.edu/CynthiaC%C3%A1rdenas?f_ri=344106","photo":"https://0.academia-photos.com/19212105/8840201/9868929/s65_cynthia.c_rdenas.jpg_oh_d30712930eb40d038e394f59ae95c3c8_oe_55e5109b___gda___1439498506_559f47722dec05bf375a24222e9bd59a"}],"research_interests":[{"id":2599,"name":"Psychometrics","url":"https://www.academia.edu/Documents/in/Psychometrics?f_ri=344106","nofollow":true},{"id":2973,"name":"Spatial cognition","url":"https://www.academia.edu/Documents/in/Spatial_cognition?f_ri=344106","nofollow":true},{"id":4212,"name":"Cognition","url":"https://www.academia.edu/Documents/in/Cognition?f_ri=344106","nofollow":true},{"id":9043,"name":"Performance","url":"https://www.academia.edu/Documents/in/Performance?f_ri=344106","nofollow":true},{"id":15838,"name":"Imagination","url":"https://www.academia.edu/Documents/in/Imagination?f_ri=344106"},{"id":43774,"name":"Learning","url":"https://www.academia.edu/Documents/in/Learning?f_ri=344106"},{"id":45349,"name":"Space perception","url":"https://www.academia.edu/Documents/in/Space_perception?f_ri=344106"},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=344106"},{"id":69056,"name":"Testosterone","url":"https://www.academia.edu/Documents/in/Testosterone?f_ri=344106"},{"id":75509,"name":"Sex Difference","url":"https://www.academia.edu/Documents/in/Sex_Difference?f_ri=344106"},{"id":89121,"name":"Circadian Rhythm","url":"https://www.academia.edu/Documents/in/Circadian_Rhythm?f_ri=344106"},{"id":97917,"name":"Spatial ability","url":"https://www.academia.edu/Documents/in/Spatial_ability?f_ri=344106"},{"id":104853,"name":"Hormones","url":"https://www.academia.edu/Documents/in/Hormones?f_ri=344106"},{"id":115306,"name":"Mental rotation","url":"https://www.academia.edu/Documents/in/Mental_rotation?f_ri=344106"},{"id":121207,"name":"Human Performance","url":"https://www.academia.edu/Documents/in/Human_Performance?f_ri=344106"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=344106"},{"id":549280,"name":"Reproducibility of Results","url":"https://www.academia.edu/Documents/in/Reproducibility_of_Results?f_ri=344106"},{"id":585597,"name":"Photoperiod","url":"https://www.academia.edu/Documents/in/Photoperiod?f_ri=344106"},{"id":918495,"name":"Sexual Differentiation","url":"https://www.academia.edu/Documents/in/Sexual_Differentiation?f_ri=344106"},{"id":993183,"name":"Young Men","url":"https://www.academia.edu/Documents/in/Young_Men?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_27214101" data-work_id="27214101" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/27214101/Salivary_microbiota_and_metabolome_associated_with_celiac_disease">Salivary microbiota and metabolome associated with celiac disease</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">This study aimed to investigate the salivary microbiota and metabolome of 13 children with celiac disease (CD) under a glutenfree diet (treated celiac disease [T-CD]). The same number of healthy children (HC) was used as controls. The... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_27214101" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">This study aimed to investigate the salivary microbiota and metabolome of 13 children with celiac disease (CD) under a glutenfree diet (treated celiac disease [T-CD]). The same number of healthy children (HC) was used as controls. The salivary microbiota was analyzed by an integrated approach using culture-dependent and -independent methods. Metabolome analysis was carried out by gas chromatography-mass spectrometry-solid-phase microextraction. Compared to HC, the number of some cultivable bacterial groups (e.g., total anaerobes) significantly (P < 0.05) differed in the saliva samples of the T-CD children. As shown by community-level catabolic profiles, the highest Shannon's diversity and substrate richness were found in HC. Pyrosequencing data showed the highest richness estimator and diversity index values for HC. Levels of Lachnospiraceae, Gemellaceae, and Streptococcus sanguinis were highest for the T-CD children. Streptococcus thermophilus levels were markedly decreased in T-CD children. The saliva of T-CD children showed the largest amount of Bacteroidetes (e.g., Porphyromonas sp., Porphyromonas endodontalis, and Prevotella nanceiensis), together with the smallest amount of Actinobacteria. T-CD children were also characterized by decreased levels of some Actinomyces species, Atopobium species, and Corynebacterium durum. Rothia mucilaginosa was the only Actinobacteria species found at the highest level in T-CD children. As shown by multivariate statistical analyses, the levels of organic volatile compounds markedly differentiated T-CD children. Some compounds (e.g., ethyl-acetate, nonanal, and 2-hexanone) were found to be associated with T-CD children. Correlations (false discovery rate [FDR], <0.05) were found between the relative abundances of bacteria and some volatile organic compounds (VOCs). The findings of this study indicated that CD is associated with oral dysbiosis that could affect the oral metabolome.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/27214101" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="8d255d413d55b39c04609d31fa81ac07" rel="nofollow" data-download="{"attachment_id":47470582,"asset_id":27214101,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/47470582/download_file?st=MTc0MDAzODkzNCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="24977853" href="https://unina.academia.edu/FrancescaDeFilippis">Francesca De Filippis</a><script data-card-contents-for-user="24977853" type="text/json">{"id":24977853,"first_name":"Francesca","last_name":"De Filippis","domain_name":"unina","page_name":"FrancescaDeFilippis","display_name":"Francesca De Filippis","profile_url":"https://unina.academia.edu/FrancescaDeFilippis?f_ri=344106","photo":"https://0.academia-photos.com/24977853/94432706/83379650/s65_francesca.de_filippis.png"}</script></span></span></li><li class="js-paper-rank-work_27214101 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="27214101"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 27214101, container: ".js-paper-rank-work_27214101", }); });</script></li><li class="js-percentile-work_27214101 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 27214101; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_27214101"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_27214101 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="27214101"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 27214101; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=27214101]").text(description); $(".js-view-count-work_27214101").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_27214101").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="27214101"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="28235" rel="nofollow" href="https://www.academia.edu/Documents/in/Multidisciplinary">Multidisciplinary</a>, <script data-card-contents-for-ri="28235" type="text/json">{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="64933" rel="nofollow" href="https://www.academia.edu/Documents/in/Child">Child</a>, <script data-card-contents-for-ri="64933" type="text/json">{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="71668" rel="nofollow" href="https://www.academia.edu/Documents/in/Celiac_Disease">Celiac Disease</a>, <script data-card-contents-for-ri="71668" type="text/json">{"id":71668,"name":"Celiac Disease","url":"https://www.academia.edu/Documents/in/Celiac_Disease?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="93418" rel="nofollow" href="https://www.academia.edu/Documents/in/Volatile_Organic_Compounds">Volatile Organic Compounds</a><script data-card-contents-for-ri="93418" type="text/json">{"id":93418,"name":"Volatile Organic Compounds","url":"https://www.academia.edu/Documents/in/Volatile_Organic_Compounds?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=27214101]'), work: {"id":27214101,"title":"Salivary microbiota and metabolome associated with celiac disease","created_at":"2016-07-24T00:50:12.754-07:00","url":"https://www.academia.edu/27214101/Salivary_microbiota_and_metabolome_associated_with_celiac_disease?f_ri=344106","dom_id":"work_27214101","summary":"This study aimed to investigate the salivary microbiota and metabolome of 13 children with celiac disease (CD) under a glutenfree diet (treated celiac disease [T-CD]). The same number of healthy children (HC) was used as controls. The salivary microbiota was analyzed by an integrated approach using culture-dependent and -independent methods. Metabolome analysis was carried out by gas chromatography-mass spectrometry-solid-phase microextraction. Compared to HC, the number of some cultivable bacterial groups (e.g., total anaerobes) significantly (P \u003c 0.05) differed in the saliva samples of the T-CD children. As shown by community-level catabolic profiles, the highest Shannon's diversity and substrate richness were found in HC. Pyrosequencing data showed the highest richness estimator and diversity index values for HC. Levels of Lachnospiraceae, Gemellaceae, and Streptococcus sanguinis were highest for the T-CD children. Streptococcus thermophilus levels were markedly decreased in T-CD children. The saliva of T-CD children showed the largest amount of Bacteroidetes (e.g., Porphyromonas sp., Porphyromonas endodontalis, and Prevotella nanceiensis), together with the smallest amount of Actinobacteria. T-CD children were also characterized by decreased levels of some Actinomyces species, Atopobium species, and Corynebacterium durum. Rothia mucilaginosa was the only Actinobacteria species found at the highest level in T-CD children. As shown by multivariate statistical analyses, the levels of organic volatile compounds markedly differentiated T-CD children. Some compounds (e.g., ethyl-acetate, nonanal, and 2-hexanone) were found to be associated with T-CD children. Correlations (false discovery rate [FDR], \u003c0.05) were found between the relative abundances of bacteria and some volatile organic compounds (VOCs). The findings of this study indicated that CD is associated with oral dysbiosis that could affect the oral metabolome.","downloadable_attachments":[{"id":47470582,"asset_id":27214101,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":24977853,"first_name":"Francesca","last_name":"De Filippis","domain_name":"unina","page_name":"FrancescaDeFilippis","display_name":"Francesca De Filippis","profile_url":"https://unina.academia.edu/FrancescaDeFilippis?f_ri=344106","photo":"https://0.academia-photos.com/24977853/94432706/83379650/s65_francesca.de_filippis.png"}],"research_interests":[{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary?f_ri=344106","nofollow":true},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=344106","nofollow":true},{"id":71668,"name":"Celiac Disease","url":"https://www.academia.edu/Documents/in/Celiac_Disease?f_ri=344106","nofollow":true},{"id":93418,"name":"Volatile Organic Compounds","url":"https://www.academia.edu/Documents/in/Volatile_Organic_Compounds?f_ri=344106","nofollow":true},{"id":107664,"name":"Applied Environmental Microbiology","url":"https://www.academia.edu/Documents/in/Applied_Environmental_Microbiology?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":529560,"name":"Gas Chromatography/mass Spectrometry","url":"https://www.academia.edu/Documents/in/Gas_Chromatography_mass_Spectrometry?f_ri=344106"},{"id":834420,"name":"Biota","url":"https://www.academia.edu/Documents/in/Biota?f_ri=344106"},{"id":1292327,"name":"Metabolome","url":"https://www.academia.edu/Documents/in/Metabolome?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_25919689" data-work_id="25919689" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/25919689/The_distribution_of_periodontopathic_bacteria_among_Japanese_children_and_their_parents">The distribution of periodontopathic bacteria among Japanese children and their parents</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">Ishikawa I. The distribution of periodontopathic bacteria among Japanese children and their parents. J Periodont Res 2004; 39; 398-404. Ó Blackwell Munksgaard 2004</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/25919689" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="31d19aaebc6cb80547193eed33db2714" rel="nofollow" data-download="{"attachment_id":46279956,"asset_id":25919689,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46279956/download_file?st=MTc0MDAzODkzNCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="49713784" href="https://independent.academia.edu/IsaoIshikawa">Isao Ishikawa</a><script data-card-contents-for-user="49713784" type="text/json">{"id":49713784,"first_name":"Isao","last_name":"Ishikawa","domain_name":"independent","page_name":"IsaoIshikawa","display_name":"Isao Ishikawa","profile_url":"https://independent.academia.edu/IsaoIshikawa?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_25919689 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="25919689"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 25919689, container: ".js-paper-rank-work_25919689", }); 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$(".js-view-count[data-work-id=25919689]").text(description); $(".js-view-count-work_25919689").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_25919689").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="25919689"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">14</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="596" rel="nofollow" href="https://www.academia.edu/Documents/in/Dentistry">Dentistry</a>, <script data-card-contents-for-ri="596" type="text/json">{"id":596,"name":"Dentistry","url":"https://www.academia.edu/Documents/in/Dentistry?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="17158" rel="nofollow" href="https://www.academia.edu/Documents/in/Japan">Japan</a>, <script data-card-contents-for-ri="17158" type="text/json">{"id":17158,"name":"Japan","url":"https://www.academia.edu/Documents/in/Japan?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="64933" rel="nofollow" href="https://www.academia.edu/Documents/in/Child">Child</a><script data-card-contents-for-ri="64933" type="text/json">{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=25919689]'), work: {"id":25919689,"title":"The distribution of periodontopathic bacteria among Japanese children and their parents","created_at":"2016-06-06T07:22:55.287-07:00","url":"https://www.academia.edu/25919689/The_distribution_of_periodontopathic_bacteria_among_Japanese_children_and_their_parents?f_ri=344106","dom_id":"work_25919689","summary":"Ishikawa I. The distribution of periodontopathic bacteria among Japanese children and their parents. J Periodont Res 2004; 39; 398-404. Ó Blackwell Munksgaard 2004","downloadable_attachments":[{"id":46279956,"asset_id":25919689,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":49713784,"first_name":"Isao","last_name":"Ishikawa","domain_name":"independent","page_name":"IsaoIshikawa","display_name":"Isao Ishikawa","profile_url":"https://independent.academia.edu/IsaoIshikawa?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":596,"name":"Dentistry","url":"https://www.academia.edu/Documents/in/Dentistry?f_ri=344106","nofollow":true},{"id":17158,"name":"Japan","url":"https://www.academia.edu/Documents/in/Japan?f_ri=344106","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=344106","nofollow":true},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=344106","nofollow":true},{"id":118339,"name":"Polymerase Chain Reaction","url":"https://www.academia.edu/Documents/in/Polymerase_Chain_Reaction?f_ri=344106"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=344106"},{"id":303598,"name":"Parents","url":"https://www.academia.edu/Documents/in/Parents?f_ri=344106"},{"id":335965,"name":"Gram-negative bacteria","url":"https://www.academia.edu/Documents/in/Gram-negative_bacteria?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":413194,"name":"Analysis of Variance","url":"https://www.academia.edu/Documents/in/Analysis_of_Variance?f_ri=344106"},{"id":477952,"name":"Dental Plaque","url":"https://www.academia.edu/Documents/in/Dental_Plaque?f_ri=344106"},{"id":584601,"name":"Chi Square Distribution","url":"https://www.academia.edu/Documents/in/Chi_Square_Distribution?f_ri=344106"},{"id":587528,"name":"Bacterial infections","url":"https://www.academia.edu/Documents/in/Bacterial_infections?f_ri=344106"},{"id":1196901,"name":"Periodontal","url":"https://www.academia.edu/Documents/in/Periodontal?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_25764335" data-work_id="25764335" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/25764335/Influence_of_Human_Saliva_on_Odorant_Concentrations_2_Aldehydes_Alcohols_3_Alkyl_2_methoxypyrazines_Methoxyphenols_and_3_Hydroxy_4_5_dimethyl_2_5_H_furanone">Influence of Human Saliva on Odorant Concentrations. 2. Aldehydes, Alcohols, 3-Alkyl-2-methoxypyrazines, Methoxyphenols, and 3-Hydroxy-4,5-dimethyl-2(5 H )-furanone</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The influence of human whole saliva on selected alcohols, aldehydes, 3-alkyl-2-methoxypyrazines, and phenols in food-relevant concentrations was investigated. At pH 7.5-8 it was found that the alcohols, methoxyphenols, methoxypyrazines,... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_25764335" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The influence of human whole saliva on selected alcohols, aldehydes, 3-alkyl-2-methoxypyrazines, and phenols in food-relevant concentrations was investigated. At pH 7.5-8 it was found that the alcohols, methoxyphenols, methoxypyrazines, and 3-hydroxy-4,5-dimethyl-2(5H)-furanone remained unmodified by saliva, whereas aldehydes were reduced to their corresponding alcohols. Generally, the processes were found to be dependent on the salivary activity of the panelists as well as on the concentration of the applied odorants. Reduction of the aldehydes did not occur after thermal treatment of the saliva. These investigations are aimed at finding an explanation for longer lasting aftertaste in humans, as it is induced by some odor-active compounds after the consumption of food materials.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/25764335" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="b7ecb52f904ba2c4a3dcbe0733f1cdb4" rel="nofollow" data-download="{"attachment_id":46121565,"asset_id":25764335,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46121565/download_file?st=MTc0MDAzODkzNSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="49410635" href="https://uni-erlangen.academia.edu/AndreaBuettner">Andrea Buettner</a><script data-card-contents-for-user="49410635" type="text/json">{"id":49410635,"first_name":"Andrea","last_name":"Buettner","domain_name":"uni-erlangen","page_name":"AndreaBuettner","display_name":"Andrea Buettner","profile_url":"https://uni-erlangen.academia.edu/AndreaBuettner?f_ri=344106","photo":"https://0.academia-photos.com/49410635/16416386/16783356/s65_andrea.buettner.jpg"}</script></span></span></li><li class="js-paper-rank-work_25764335 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="25764335"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 25764335, container: ".js-paper-rank-work_25764335", }); });</script></li><li class="js-percentile-work_25764335 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 25764335; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_25764335"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_25764335 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="25764335"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 25764335; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=25764335]").text(description); $(".js-view-count-work_25764335").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_25764335").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="25764335"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">18</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="48" rel="nofollow" href="https://www.academia.edu/Documents/in/Engineering">Engineering</a>, <script data-card-contents-for-ri="48" type="text/json">{"id":48,"name":"Engineering","url":"https://www.academia.edu/Documents/in/Engineering?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="14925" rel="nofollow" href="https://www.academia.edu/Documents/in/Heat_Treatment">Heat Treatment</a>, <script data-card-contents-for-ri="14925" type="text/json">{"id":14925,"name":"Heat Treatment","url":"https://www.academia.edu/Documents/in/Heat_Treatment?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="23890" rel="nofollow" href="https://www.academia.edu/Documents/in/Comparative_Study">Comparative Study</a>, <script data-card-contents-for-ri="23890" type="text/json">{"id":23890,"name":"Comparative Study","url":"https://www.academia.edu/Documents/in/Comparative_Study?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="39719" rel="nofollow" href="https://www.academia.edu/Documents/in/Food_Analysis">Food Analysis</a><script data-card-contents-for-ri="39719" type="text/json">{"id":39719,"name":"Food Analysis","url":"https://www.academia.edu/Documents/in/Food_Analysis?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=25764335]'), work: {"id":25764335,"title":"Influence of Human Saliva on Odorant Concentrations. 2. Aldehydes, Alcohols, 3-Alkyl-2-methoxypyrazines, Methoxyphenols, and 3-Hydroxy-4,5-dimethyl-2(5 H )-furanone","created_at":"2016-05-31T23:51:22.618-07:00","url":"https://www.academia.edu/25764335/Influence_of_Human_Saliva_on_Odorant_Concentrations_2_Aldehydes_Alcohols_3_Alkyl_2_methoxypyrazines_Methoxyphenols_and_3_Hydroxy_4_5_dimethyl_2_5_H_furanone?f_ri=344106","dom_id":"work_25764335","summary":"The influence of human whole saliva on selected alcohols, aldehydes, 3-alkyl-2-methoxypyrazines, and phenols in food-relevant concentrations was investigated. At pH 7.5-8 it was found that the alcohols, methoxyphenols, methoxypyrazines, and 3-hydroxy-4,5-dimethyl-2(5H)-furanone remained unmodified by saliva, whereas aldehydes were reduced to their corresponding alcohols. Generally, the processes were found to be dependent on the salivary activity of the panelists as well as on the concentration of the applied odorants. Reduction of the aldehydes did not occur after thermal treatment of the saliva. These investigations are aimed at finding an explanation for longer lasting aftertaste in humans, as it is induced by some odor-active compounds after the consumption of food materials.","downloadable_attachments":[{"id":46121565,"asset_id":25764335,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":49410635,"first_name":"Andrea","last_name":"Buettner","domain_name":"uni-erlangen","page_name":"AndreaBuettner","display_name":"Andrea Buettner","profile_url":"https://uni-erlangen.academia.edu/AndreaBuettner?f_ri=344106","photo":"https://0.academia-photos.com/49410635/16416386/16783356/s65_andrea.buettner.jpg"}],"research_interests":[{"id":48,"name":"Engineering","url":"https://www.academia.edu/Documents/in/Engineering?f_ri=344106","nofollow":true},{"id":14925,"name":"Heat Treatment","url":"https://www.academia.edu/Documents/in/Heat_Treatment?f_ri=344106","nofollow":true},{"id":23890,"name":"Comparative Study","url":"https://www.academia.edu/Documents/in/Comparative_Study?f_ri=344106","nofollow":true},{"id":39719,"name":"Food Analysis","url":"https://www.academia.edu/Documents/in/Food_Analysis?f_ri=344106","nofollow":true},{"id":86176,"name":"Alcohol","url":"https://www.academia.edu/Documents/in/Alcohol?f_ri=344106"},{"id":165437,"name":"Taste","url":"https://www.academia.edu/Documents/in/Taste?f_ri=344106"},{"id":260118,"name":"CHEMICAL SCIENCES","url":"https://www.academia.edu/Documents/in/CHEMICAL_SCIENCES?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":347988,"name":"Phenols","url":"https://www.academia.edu/Documents/in/Phenols?f_ri=344106"},{"id":357416,"name":"Odors","url":"https://www.academia.edu/Documents/in/Odors?f_ri=344106"},{"id":529560,"name":"Gas Chromatography/mass Spectrometry","url":"https://www.academia.edu/Documents/in/Gas_Chromatography_mass_Spectrometry?f_ri=344106"},{"id":539878,"name":"Chemical Reaction","url":"https://www.academia.edu/Documents/in/Chemical_Reaction?f_ri=344106"},{"id":540337,"name":"Flavor","url":"https://www.academia.edu/Documents/in/Flavor?f_ri=344106"},{"id":596974,"name":"Agricultural and Food Chemistry","url":"https://www.academia.edu/Documents/in/Agricultural_and_Food_Chemistry?f_ri=344106"},{"id":1137254,"name":"Hydrogen-Ion Concentration","url":"https://www.academia.edu/Documents/in/Hydrogen-Ion_Concentration?f_ri=344106"},{"id":1260097,"name":"Furans","url":"https://www.academia.edu/Documents/in/Furans?f_ri=344106"},{"id":1294622,"name":"Alcohols","url":"https://www.academia.edu/Documents/in/Alcohols?f_ri=344106"},{"id":2230327,"name":"Aldehydes","url":"https://www.academia.edu/Documents/in/Aldehydes?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_14033417" data-work_id="14033417" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/14033417/Developmental_changes_in_baseline_cortisol_activity_in_early_childhood_Relations_with_napping_and_effortful_control">Developmental changes in baseline cortisol activity in early childhood: Relations with napping and effortful control</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Development of the hypothalamic-pituitary-adrenocortical (HPA) axis was examined using salivary cortisol levels assessed at wake-up, midmorning, midafternoon, and bedtime in 77 children aged 12, 18, 24, 30, and 36 months, in a... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_14033417" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Development of the hypothalamic-pituitary-adrenocortical (HPA) axis was examined using salivary cortisol levels assessed at wake-up, midmorning, midafternoon, and bedtime in 77 children aged 12, 18, 24, 30, and 36 months, in a cross-sectional design. Hierarchical linear modeling (HLM) analyses were used to characterize cortisol production across the day and to examine age-related differences. Using area(s) under the curve (AUC), cortisol levels were higher among the 12-, 18-, and 24-month children than among the 30-and 36-month children. For all five age groups, cortisol levels were highest at wake-up and lowest at bedtime. Significant decreases were noted between wake-up and midmorning, and between midafternoon and bedtime. Unlike adults, midafternoon cortisol levels were not significantly lower than midmorning levels. Over this age period, children napped less and scored increasingly higher on parent reports of effortful control. Among the 30-and 36-month children, shorter naps were associated with more adultlike decreases in cortisol levels from midmorning to midafternoon. Considering all of the age groups together, effortful control correlated negatively with cortisol levels after controlling for age. These results suggest that circadian regulation of the HPA axis continues to mature into the third year in humans, and that its maturation corresponds to aspects of behavioral development. ß 2004 Wiley Periodicals, Inc. Dev Psychobiol 45: 125-133, 2004.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/14033417" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="677a07caf40db5cb9e1ae5b8a3f47151" rel="nofollow" data-download="{"attachment_id":44682661,"asset_id":14033417,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44682661/download_file?st=MTc0MDAzODkzNSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33060249" href="https://independent.academia.edu/DarleneKertes">Darlene Kertes</a><script data-card-contents-for-user="33060249" type="text/json">{"id":33060249,"first_name":"Darlene","last_name":"Kertes","domain_name":"independent","page_name":"DarleneKertes","display_name":"Darlene Kertes","profile_url":"https://independent.academia.edu/DarleneKertes?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_14033417 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="14033417"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 14033417, container: ".js-paper-rank-work_14033417", }); 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$(".js-view-count[data-work-id=14033417]").text(description); $(".js-view-count-work_14033417").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_14033417").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="14033417"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">20</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="237" rel="nofollow" href="https://www.academia.edu/Documents/in/Cognitive_Science">Cognitive Science</a>, <script data-card-contents-for-ri="237" type="text/json">{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="3595" rel="nofollow" href="https://www.academia.edu/Documents/in/Individuality">Individuality</a>, <script data-card-contents-for-ri="3595" type="text/json">{"id":3595,"name":"Individuality","url":"https://www.academia.edu/Documents/in/Individuality?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4583" rel="nofollow" href="https://www.academia.edu/Documents/in/Child_Development">Child Development</a><script data-card-contents-for-ri="4583" type="text/json">{"id":4583,"name":"Child Development","url":"https://www.academia.edu/Documents/in/Child_Development?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=14033417]'), work: {"id":14033417,"title":"Developmental changes in baseline cortisol activity in early childhood: Relations with napping and effortful control","created_at":"2015-07-14T07:16:48.192-07:00","url":"https://www.academia.edu/14033417/Developmental_changes_in_baseline_cortisol_activity_in_early_childhood_Relations_with_napping_and_effortful_control?f_ri=344106","dom_id":"work_14033417","summary":"Development of the hypothalamic-pituitary-adrenocortical (HPA) axis was examined using salivary cortisol levels assessed at wake-up, midmorning, midafternoon, and bedtime in 77 children aged 12, 18, 24, 30, and 36 months, in a cross-sectional design. Hierarchical linear modeling (HLM) analyses were used to characterize cortisol production across the day and to examine age-related differences. Using area(s) under the curve (AUC), cortisol levels were higher among the 12-, 18-, and 24-month children than among the 30-and 36-month children. For all five age groups, cortisol levels were highest at wake-up and lowest at bedtime. Significant decreases were noted between wake-up and midmorning, and between midafternoon and bedtime. Unlike adults, midafternoon cortisol levels were not significantly lower than midmorning levels. Over this age period, children napped less and scored increasingly higher on parent reports of effortful control. Among the 30-and 36-month children, shorter naps were associated with more adultlike decreases in cortisol levels from midmorning to midafternoon. Considering all of the age groups together, effortful control correlated negatively with cortisol levels after controlling for age. These results suggest that circadian regulation of the HPA axis continues to mature into the third year in humans, and that its maturation corresponds to aspects of behavioral development. ß 2004 Wiley Periodicals, Inc. Dev Psychobiol 45: 125-133, 2004.","downloadable_attachments":[{"id":44682661,"asset_id":14033417,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33060249,"first_name":"Darlene","last_name":"Kertes","domain_name":"independent","page_name":"DarleneKertes","display_name":"Darlene Kertes","profile_url":"https://independent.academia.edu/DarleneKertes?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=344106","nofollow":true},{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=344106","nofollow":true},{"id":3595,"name":"Individuality","url":"https://www.academia.edu/Documents/in/Individuality?f_ri=344106","nofollow":true},{"id":4583,"name":"Child Development","url":"https://www.academia.edu/Documents/in/Child_Development?f_ri=344106","nofollow":true},{"id":30140,"name":"Early Childhood","url":"https://www.academia.edu/Documents/in/Early_Childhood?f_ri=344106"},{"id":57810,"name":"Child Behavior","url":"https://www.academia.edu/Documents/in/Child_Behavior?f_ri=344106"},{"id":58431,"name":"Cortisol","url":"https://www.academia.edu/Documents/in/Cortisol?f_ri=344106"},{"id":85043,"name":"Developmental Psychobiology","url":"https://www.academia.edu/Documents/in/Developmental_Psychobiology?f_ri=344106"},{"id":89121,"name":"Circadian Rhythm","url":"https://www.academia.edu/Documents/in/Circadian_Rhythm?f_ri=344106"},{"id":133324,"name":"Sleep","url":"https://www.academia.edu/Documents/in/Sleep?f_ri=344106"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=344106"},{"id":134348,"name":"Temperament","url":"https://www.academia.edu/Documents/in/Temperament?f_ri=344106"},{"id":229238,"name":"Developmental","url":"https://www.academia.edu/Documents/in/Developmental?f_ri=344106"},{"id":294768,"name":"Wakefulness","url":"https://www.academia.edu/Documents/in/Wakefulness?f_ri=344106"},{"id":306766,"name":"Arousal","url":"https://www.academia.edu/Documents/in/Arousal?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":879093,"name":"Napping","url":"https://www.academia.edu/Documents/in/Napping?f_ri=344106"},{"id":1000427,"name":"Reference Values","url":"https://www.academia.edu/Documents/in/Reference_Values?f_ri=344106"},{"id":1034181,"name":"Cross Sectional Studies","url":"https://www.academia.edu/Documents/in/Cross_Sectional_Studies?f_ri=344106"},{"id":2051024,"name":"Infant Behavior","url":"https://www.academia.edu/Documents/in/Infant_Behavior?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_23877167" data-work_id="23877167" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/23877167/The_Effect_of_the_Binge_Drinking_Session_on_the_Activity_of_Salivary_Serum_and_Urinary_Hexosaminidase_Preliminary_Data">The Effect of the Binge Drinking Session on the Activity of Salivary, Serum and Urinary -Hexosaminidase: Preliminary Data</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Our report is the first to show that an acute ingestion (6 h) of a relatively large, yet tolerable dose of alcohol (120-160 g), significantly increases activity of total serum β-hexosaminidase (total β-HEX), β-HEX A and β-HEX B... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_23877167" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Our report is the first to show that an acute ingestion (6 h) of a relatively large, yet tolerable dose of alcohol (120-160 g), significantly increases activity of total serum β-hexosaminidase (total β-HEX), β-HEX A and β-HEX B isoenzymes, as well as salivary total β-HEX and urinary β-HEX A, in eight infrequent binge drinkers. An increase in the activity of serum and urinary total HEX is mainly due to its secretory isoenzyme β-HEX A.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/23877167" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="146b0109e82e159cd66ce78117fea6e6" rel="nofollow" data-download="{"attachment_id":44267683,"asset_id":23877167,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44267683/download_file?st=MTc0MDAzODkzNSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="46146279" href="https://independent.academia.edu/KZwierz">K. Zwierz</a><script data-card-contents-for-user="46146279" type="text/json">{"id":46146279,"first_name":"K.","last_name":"Zwierz","domain_name":"independent","page_name":"KZwierz","display_name":"K. 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An increase in the activity of serum and urinary total HEX is mainly due to its secretory isoenzyme β-HEX A.","downloadable_attachments":[{"id":44267683,"asset_id":23877167,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":46146279,"first_name":"K.","last_name":"Zwierz","domain_name":"independent","page_name":"KZwierz","display_name":"K. Zwierz","profile_url":"https://independent.academia.edu/KZwierz?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=344106","nofollow":true},{"id":86176,"name":"Alcohol","url":"https://www.academia.edu/Documents/in/Alcohol?f_ri=344106","nofollow":true},{"id":110254,"name":"Alcohol Drinking","url":"https://www.academia.edu/Documents/in/Alcohol_Drinking?f_ri=344106","nofollow":true},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106","nofollow":true},{"id":402006,"name":"Binge drinking","url":"https://www.academia.edu/Documents/in/Binge_drinking?f_ri=344106"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=344106"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_15416581 coauthored" data-work_id="15416581" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/15416581/Salivary_%CE%B1_amylase_stress_reactivity_across_different_age_groups">Salivary α-amylase stress reactivity across different age groups</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Salivary a-amylase (sAA) increases rapidly in response to psychosocial stress in young adults, but no direct comparisons between different age groups across the life span have been made. Secretion of sAA and cortisol was assessed in... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_15416581" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Salivary a-amylase (sAA) increases rapidly in response to psychosocial stress in young adults, but no direct comparisons between different age groups across the life span have been made. Secretion of sAA and cortisol was assessed in children, young adults, and older adults after exposure to the Trier Social Stress Test. Additionally, cardiovascular activity was measured in both adult groups. Older adults showed attenuated sAA, heart rate (HR), and heart rate variability (HRV) responses. Furthermore, we found higher sAA but lower cortisol at baseline as well as lower sAA and cortisol responses in children. Age Â sex interactions were observed only for cortisol with higher responses in older male participants. No associations between the parameters were found. These results implicate sAA as an alternative or additional sympathetic stress marker throughout the life span, with marked and rapid stress responsiveness in three relevant age groups.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/15416581" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="fcfa6cae3600e349dc5d2c1811160ff0" rel="nofollow" data-download="{"attachment_id":43218798,"asset_id":15416581,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/43218798/download_file?st=MTc0MDAzODkzNSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="34562016" href="https://uni-erlangen.academia.edu/NicolasRohleder">Nicolas Rohleder</a><script data-card-contents-for-user="34562016" type="text/json">{"id":34562016,"first_name":"Nicolas","last_name":"Rohleder","domain_name":"uni-erlangen","page_name":"NicolasRohleder","display_name":"Nicolas Rohleder","profile_url":"https://uni-erlangen.academia.edu/NicolasRohleder?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-15416581">+1</span><div class="hidden js-additional-users-15416581"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/JanaStrahler">Jana Strahler</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-15416581'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-15416581').html(); 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Secretion of sAA and cortisol was assessed in children, young adults, and older adults after exposure to the Trier Social Stress Test. Additionally, cardiovascular activity was measured in both adult groups. Older adults showed attenuated sAA, heart rate (HR), and heart rate variability (HRV) responses. Furthermore, we found higher sAA but lower cortisol at baseline as well as lower sAA and cortisol responses in children. Age Â sex interactions were observed only for cortisol with higher responses in older male participants. No associations between the parameters were found. These results implicate sAA as an alternative or additional sympathetic stress marker throughout the life span, with marked and rapid stress responsiveness in three relevant age groups.","downloadable_attachments":[{"id":43218798,"asset_id":15416581,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":34562016,"first_name":"Nicolas","last_name":"Rohleder","domain_name":"uni-erlangen","page_name":"NicolasRohleder","display_name":"Nicolas Rohleder","profile_url":"https://uni-erlangen.academia.edu/NicolasRohleder?f_ri=344106","photo":"/images/s65_no_pic.png"},{"id":34622748,"first_name":"Jana","last_name":"Strahler","domain_name":"independent","page_name":"JanaStrahler","display_name":"Jana Strahler","profile_url":"https://independent.academia.edu/JanaStrahler?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":1026,"name":"Psychophysiology","url":"https://www.academia.edu/Documents/in/Psychophysiology?f_ri=344106","nofollow":true},{"id":2599,"name":"Psychometrics","url":"https://www.academia.edu/Documents/in/Psychometrics?f_ri=344106","nofollow":true},{"id":6791,"name":"Aging","url":"https://www.academia.edu/Documents/in/Aging?f_ri=344106","nofollow":true},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=344106","nofollow":true},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=344106"},{"id":131298,"name":"Heart rate","url":"https://www.academia.edu/Documents/in/Heart_rate?f_ri=344106"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":675419,"name":"Sympathetic Nervous System","url":"https://www.academia.edu/Documents/in/Sympathetic_Nervous_System?f_ri=344106"},{"id":806178,"name":"Older Adult","url":"https://www.academia.edu/Documents/in/Older_Adult?f_ri=344106"},{"id":979555,"name":"Salivary Alpha Amylase","url":"https://www.academia.edu/Documents/in/Salivary_Alpha_Amylase?f_ri=344106"},{"id":1470936,"name":"Age Groups","url":"https://www.academia.edu/Documents/in/Age_Groups?f_ri=344106"},{"id":2016105,"name":"Acute stress","url":"https://www.academia.edu/Documents/in/Acute_stress?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_19608441" data-work_id="19608441" itemscope="itemscope" 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href="https://www.academia.edu/19325387/Individual_differences_in_utilizing_control_to_cope_with_job_demands_Effects_on_susceptibility_to_infectious_disease">Individual differences in utilizing control to cope with job demands: Effects on susceptibility to infectious disease</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">This study examined the interactive effects of job demands, control, and individual characteristics on upper respiratory illnesses and immune function. Having high job control appeared to lessen the linkage between job demands and poor... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_19325387" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">This study examined the interactive effects of job demands, control, and individual characteristics on upper respiratory illnesses and immune function. Having high job control appeared to lessen the linkage between job demands and poor health among individuals with high self-efficacy and those who perceived that they were not often responsible for negative job outcomes. Conversely, having high job control exacerbated the association between job demands and poor health among inefficacious individuals. Implications for promoting more healthful work environments and facilitating employee coping are discussed.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/19325387" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="2d2a506a702fb422fc70e609fea69f67" rel="nofollow" data-download="{"attachment_id":40557151,"asset_id":19325387,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/40557151/download_file?st=MTc0MDAzODkzNSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="39581121" href="https://independent.academia.edu/JohnSchaubroeck">John Schaubroeck</a><script data-card-contents-for-user="39581121" type="text/json">{"id":39581121,"first_name":"John","last_name":"Schaubroeck","domain_name":"independent","page_name":"JohnSchaubroeck","display_name":"John Schaubroeck","profile_url":"https://independent.academia.edu/JohnSchaubroeck?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_19325387 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="19325387"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 19325387, container: ".js-paper-rank-work_19325387", }); 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The plaque index,... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_17755166" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">This case-controlled study examined clinical and microbiological parameters in Brazilian children and adolescents receiving orthodontic treatment using fixed orthodontic appliances or removable orthodontic appliances. The plaque index, gingival index, number of decayed, missing and filled teeth, and probing pocket depth was measured on each fully erupted tooth in 30 patients treated with fixed orthodontic appliances and an equal number of age and sex-matched control subjects. The same parameters were also measured in 18 patients treated with removable orthodontic appliances and an equal number of age and sex-matched control subjects. In the patients treated with fixed orthodontic appliances, subgingival plaque samples were collected from four teeth with orthodontic brackets and from four teeth with orthodontic bands. In the patients with removable appliances, subgingival plaque samples were collected from clasped maxillary permanent first molar teeth and from four unclasped permanen...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/17755166" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="1c5f5d08a0c1f5a22db05252f7ea1857" rel="nofollow" data-download="{"attachment_id":39692319,"asset_id":17755166,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/39692319/download_file?st=MTc0MDAzODkzNSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="37662039" href="https://independent.academia.edu/JosephZambon">Joseph Zambon</a><script data-card-contents-for-user="37662039" type="text/json">{"id":37662039,"first_name":"Joseph","last_name":"Zambon","domain_name":"independent","page_name":"JosephZambon","display_name":"Joseph Zambon","profile_url":"https://independent.academia.edu/JosephZambon?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-17755166">+2</span><div class="hidden js-additional-users-17755166"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/RegoRodrigo">Rodrigo Rego</a></span></div><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/VioletHaraszthy">Violet Haraszthy</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-17755166'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-17755166').html(); 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container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_17755166 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="17755166"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17755166; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17755166]").text(description); $(".js-view-count-work_17755166").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_17755166").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="17755166"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">10</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="596" rel="nofollow" href="https://www.academia.edu/Documents/in/Dentistry">Dentistry</a>, <script data-card-contents-for-ri="596" type="text/json">{"id":596,"name":"Dentistry","url":"https://www.academia.edu/Documents/in/Dentistry?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="64933" rel="nofollow" href="https://www.academia.edu/Documents/in/Child">Child</a>, <script data-card-contents-for-ri="64933" type="text/json">{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="288513" rel="nofollow" href="https://www.academia.edu/Documents/in/Orthodontic_Brackets">Orthodontic Brackets</a><script data-card-contents-for-ri="288513" type="text/json">{"id":288513,"name":"Orthodontic Brackets","url":"https://www.academia.edu/Documents/in/Orthodontic_Brackets?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=17755166]'), work: {"id":17755166,"title":"Clinical and microbiological studies of children and adolescents receiving orthodontic treatment","created_at":"2015-11-04T12:13:00.000-08:00","url":"https://www.academia.edu/17755166/Clinical_and_microbiological_studies_of_children_and_adolescents_receiving_orthodontic_treatment?f_ri=344106","dom_id":"work_17755166","summary":"This case-controlled study examined clinical and microbiological parameters in Brazilian children and adolescents receiving orthodontic treatment using fixed orthodontic appliances or removable orthodontic appliances. The plaque index, gingival index, number of decayed, missing and filled teeth, and probing pocket depth was measured on each fully erupted tooth in 30 patients treated with fixed orthodontic appliances and an equal number of age and sex-matched control subjects. The same parameters were also measured in 18 patients treated with removable orthodontic appliances and an equal number of age and sex-matched control subjects. In the patients treated with fixed orthodontic appliances, subgingival plaque samples were collected from four teeth with orthodontic brackets and from four teeth with orthodontic bands. In the patients with removable appliances, subgingival plaque samples were collected from clasped maxillary permanent first molar teeth and from four unclasped permanen...","downloadable_attachments":[{"id":39692319,"asset_id":17755166,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":37662039,"first_name":"Joseph","last_name":"Zambon","domain_name":"independent","page_name":"JosephZambon","display_name":"Joseph Zambon","profile_url":"https://independent.academia.edu/JosephZambon?f_ri=344106","photo":"/images/s65_no_pic.png"},{"id":47161021,"first_name":"Rodrigo","last_name":"Rego","domain_name":"independent","page_name":"RegoRodrigo","display_name":"Rodrigo Rego","profile_url":"https://independent.academia.edu/RegoRodrigo?f_ri=344106","photo":"/images/s65_no_pic.png"},{"id":37786769,"first_name":"Violet","last_name":"Haraszthy","domain_name":"independent","page_name":"VioletHaraszthy","display_name":"Violet Haraszthy","profile_url":"https://independent.academia.edu/VioletHaraszthy?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":596,"name":"Dentistry","url":"https://www.academia.edu/Documents/in/Dentistry?f_ri=344106","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=344106","nofollow":true},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=344106","nofollow":true},{"id":288513,"name":"Orthodontic Brackets","url":"https://www.academia.edu/Documents/in/Orthodontic_Brackets?f_ri=344106","nofollow":true},{"id":335965,"name":"Gram-negative bacteria","url":"https://www.academia.edu/Documents/in/Gram-negative_bacteria?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":477952,"name":"Dental Plaque","url":"https://www.academia.edu/Documents/in/Dental_Plaque?f_ri=344106"},{"id":548506,"name":"ORTHODONTIC appliances","url":"https://www.academia.edu/Documents/in/ORTHODONTIC_appliances?f_ri=344106"},{"id":584598,"name":"Dental Plaque Index","url":"https://www.academia.edu/Documents/in/Dental_Plaque_Index?f_ri=344106"},{"id":1819399,"name":"Case Control Studies","url":"https://www.academia.edu/Documents/in/Case_Control_Studies?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_64793222" data-work_id="64793222" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" rel="nofollow" href="https://www.academia.edu/64793222/EFFECT_OF_DENTIFRICE_CONTAINING_SALT_ON_SALIVARY_SODIUM_AND_CHLORIDE_IONS_IN_PREHYPERTENSIVE_PATIENTS">EFFECT OF DENTIFRICE CONTAINING SALT ON SALIVARY SODIUM AND CHLORIDE IONS IN PREHYPERTENSIVE PATIENTS</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objective: effects of their use on clinical parameters .However the systemic absorption & health usually go unexplored. Hence this present randomised controlled double blinded cross design clinical study compared the changes in sodium and... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_64793222" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objective: effects of their use on clinical parameters .However the systemic absorption & health usually go unexplored. Hence this present randomised controlled double blinded cross design clinical study compared the changes in sodium and chloride ions & blood pressure brought about by using a dentifrice containing sal Material and Methods baseline saliva samples. Subjects were then randomly assigned a test/control dentifrice to be brushed with twice daily for the next 28 days. On the 29 hygiene and provided saliva samples similar to that collected at baseline. An additional 2 washout dentifrice. Blood pressure was Results: significant increase(p<0.05) in salivary sodium ions post 4 week usage of salt containing dentifrice as compared to However chloride ions and the blood pressure in both groups showed no significant change from baseline in both groups. Conclusions: containing salt.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/64793222" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="d070099bcf4098d12ced362d0df116cc" rel="nofollow" data-download="{"attachment_id":76662919,"asset_id":64793222,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/76662919/download_file?st=MTc0MDAzODkzNSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="26003022" rel="nofollow" href="https://santoshuniversity.academia.edu/arunanautiyal">aruna nautiyal</a><script data-card-contents-for-user="26003022" type="text/json">{"id":26003022,"first_name":"aruna","last_name":"nautiyal","domain_name":"santoshuniversity","page_name":"arunanautiyal","display_name":"aruna nautiyal","profile_url":"https://santoshuniversity.academia.edu/arunanautiyal?f_ri=344106","photo":"https://0.academia-photos.com/26003022/70290566/58706196/s65_aruna.nautiyal.jpg"}</script></span></span></li><li class="js-paper-rank-work_64793222 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="64793222"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 64793222, container: ".js-paper-rank-work_64793222", }); });</script></li><li class="js-percentile-work_64793222 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 64793222; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_64793222"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_64793222 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="64793222"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 64793222; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=64793222]").text(description); $(".js-view-count-work_64793222").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_64793222").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="64793222"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">5</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="71399" rel="nofollow" href="https://www.academia.edu/Documents/in/Hypertension">Hypertension</a>, <script data-card-contents-for-ri="71399" type="text/json">{"id":71399,"name":"Hypertension","url":"https://www.academia.edu/Documents/in/Hypertension?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="344106" rel="nofollow" href="https://www.academia.edu/Documents/in/Saliva">Saliva</a>, <script data-card-contents-for-ri="344106" type="text/json">{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="546346" rel="nofollow" href="https://www.academia.edu/Documents/in/Dentifrice">Dentifrice</a>, <script data-card-contents-for-ri="546346" type="text/json">{"id":546346,"name":"Dentifrice","url":"https://www.academia.edu/Documents/in/Dentifrice?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="1223913" rel="nofollow" href="https://www.academia.edu/Documents/in/Sodium_Chloride">Sodium Chloride</a><script data-card-contents-for-ri="1223913" type="text/json">{"id":1223913,"name":"Sodium Chloride","url":"https://www.academia.edu/Documents/in/Sodium_Chloride?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=64793222]'), work: {"id":64793222,"title":"EFFECT OF DENTIFRICE CONTAINING SALT ON SALIVARY SODIUM AND CHLORIDE IONS IN PREHYPERTENSIVE PATIENTS","created_at":"2021-12-17T04:07:23.332-08:00","url":"https://www.academia.edu/64793222/EFFECT_OF_DENTIFRICE_CONTAINING_SALT_ON_SALIVARY_SODIUM_AND_CHLORIDE_IONS_IN_PREHYPERTENSIVE_PATIENTS?f_ri=344106","dom_id":"work_64793222","summary":"Objective: effects of their use on clinical parameters .However the systemic absorption \u0026 health usually go unexplored. Hence this present randomised controlled double blinded cross design clinical study compared the changes in sodium and chloride ions \u0026 blood pressure brought about by using a dentifrice containing sal Material and Methods baseline saliva samples. Subjects were then randomly assigned a test/control dentifrice to be brushed with twice daily for the next 28 days. On the 29 hygiene and provided saliva samples similar to that collected at baseline. An additional 2 washout dentifrice. Blood pressure was Results: significant increase(p\u003c0.05) in salivary sodium ions post 4 week usage of salt containing dentifrice as compared to However chloride ions and the blood pressure in both groups showed no significant change from baseline in both groups. Conclusions: containing salt.","downloadable_attachments":[{"id":76662919,"asset_id":64793222,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":26003022,"first_name":"aruna","last_name":"nautiyal","domain_name":"santoshuniversity","page_name":"arunanautiyal","display_name":"aruna nautiyal","profile_url":"https://santoshuniversity.academia.edu/arunanautiyal?f_ri=344106","photo":"https://0.academia-photos.com/26003022/70290566/58706196/s65_aruna.nautiyal.jpg"}],"research_interests":[{"id":71399,"name":"Hypertension","url":"https://www.academia.edu/Documents/in/Hypertension?f_ri=344106","nofollow":true},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106","nofollow":true},{"id":546346,"name":"Dentifrice","url":"https://www.academia.edu/Documents/in/Dentifrice?f_ri=344106","nofollow":true},{"id":1223913,"name":"Sodium Chloride","url":"https://www.academia.edu/Documents/in/Sodium_Chloride?f_ri=344106","nofollow":true},{"id":3076502,"name":"dentifrices","url":"https://www.academia.edu/Documents/in/dentifrices?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_60688277" data-work_id="60688277" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/60688277/Human_experimental_caries_models_intra_oral_environmental_variability">Human experimental caries models: intra-oral environmental variability</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">In situ caries models serve purposes other than just being a simpler way to obtain data than running a clinical trial. However, variation in information obtained not only among individuals but also, in particular, depending on different... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_60688277" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">In situ caries models serve purposes other than just being a simpler way to obtain data than running a clinical trial. However, variation in information obtained not only among individuals but also, in particular, depending on different locations of the models within the oral cavity have so far been given little attention. In the present review, the aim has been to characterize the different designs of in situ caries models and to describe some important factors which may vary within the oral cavity and thus influence the outcome of the way the different in situ models are used. Advantages and disadvantages of in vivo models vs. in situ models are discussed. In the latter case, the distinction is made between dental appliance models and so-called &quot;single tooth&quot; models. The review concludes that in situ models differ distinctly with regard to their &quot;biological potential&quot;. Because of regional differences in salivary film velocity, pH, and composition of the microfl...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/60688277" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="7dbddbfdc3473685b35c31fa7cd33f7d" rel="nofollow" data-download="{"attachment_id":74019958,"asset_id":60688277,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/74019958/download_file?st=MTc0MDAzODkzNSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33506289" href="https://au.academia.edu/OleFejerskov">Ole Fejerskov</a><script data-card-contents-for-user="33506289" type="text/json">{"id":33506289,"first_name":"Ole","last_name":"Fejerskov","domain_name":"au","page_name":"OleFejerskov","display_name":"Ole Fejerskov","profile_url":"https://au.academia.edu/OleFejerskov?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_60688277 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="60688277"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 60688277, container: ".js-paper-rank-work_60688277", }); });</script></li><li class="js-percentile-work_60688277 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 60688277; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_60688277"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_60688277 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="60688277"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 60688277; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=60688277]").text(description); $(".js-view-count-work_60688277").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_60688277").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="60688277"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="596" rel="nofollow" href="https://www.academia.edu/Documents/in/Dentistry">Dentistry</a>, <script data-card-contents-for-ri="596" type="text/json">{"id":596,"name":"Dentistry","url":"https://www.academia.edu/Documents/in/Dentistry?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="2066" rel="nofollow" href="https://www.academia.edu/Documents/in/Research_Design">Research Design</a>, <script data-card-contents-for-ri="2066" type="text/json">{"id":2066,"name":"Research Design","url":"https://www.academia.edu/Documents/in/Research_Design?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="105826" rel="nofollow" href="https://www.academia.edu/Documents/in/Dental_Caries">Dental Caries</a>, <script data-card-contents-for-ri="105826" type="text/json">{"id":105826,"name":"Dental Caries","url":"https://www.academia.edu/Documents/in/Dental_Caries?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="137728" rel="nofollow" href="https://www.academia.edu/Documents/in/Dental">Dental</a><script data-card-contents-for-ri="137728" type="text/json">{"id":137728,"name":"Dental","url":"https://www.academia.edu/Documents/in/Dental?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=60688277]'), work: {"id":60688277,"title":"Human experimental caries models: intra-oral environmental variability","created_at":"2021-11-01T05:13:29.332-07:00","url":"https://www.academia.edu/60688277/Human_experimental_caries_models_intra_oral_environmental_variability?f_ri=344106","dom_id":"work_60688277","summary":"In situ caries models serve purposes other than just being a simpler way to obtain data than running a clinical trial. However, variation in information obtained not only among individuals but also, in particular, depending on different locations of the models within the oral cavity have so far been given little attention. In the present review, the aim has been to characterize the different designs of in situ caries models and to describe some important factors which may vary within the oral cavity and thus influence the outcome of the way the different in situ models are used. Advantages and disadvantages of in vivo models vs. in situ models are discussed. In the latter case, the distinction is made between dental appliance models and so-called \u0026quot;single tooth\u0026quot; models. The review concludes that in situ models differ distinctly with regard to their \u0026quot;biological potential\u0026quot;. Because of regional differences in salivary film velocity, pH, and composition of the microfl...","downloadable_attachments":[{"id":74019958,"asset_id":60688277,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33506289,"first_name":"Ole","last_name":"Fejerskov","domain_name":"au","page_name":"OleFejerskov","display_name":"Ole Fejerskov","profile_url":"https://au.academia.edu/OleFejerskov?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":596,"name":"Dentistry","url":"https://www.academia.edu/Documents/in/Dentistry?f_ri=344106","nofollow":true},{"id":2066,"name":"Research Design","url":"https://www.academia.edu/Documents/in/Research_Design?f_ri=344106","nofollow":true},{"id":105826,"name":"Dental Caries","url":"https://www.academia.edu/Documents/in/Dental_Caries?f_ri=344106","nofollow":true},{"id":137728,"name":"Dental","url":"https://www.academia.edu/Documents/in/Dental?f_ri=344106","nofollow":true},{"id":156545,"name":"Environmental Variables","url":"https://www.academia.edu/Documents/in/Environmental_Variables?f_ri=344106"},{"id":187761,"name":"Human Experimentation","url":"https://www.academia.edu/Documents/in/Human_Experimentation?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":373754,"name":"Ecosystem","url":"https://www.academia.edu/Documents/in/Ecosystem?f_ri=344106"},{"id":477952,"name":"Dental Plaque","url":"https://www.academia.edu/Documents/in/Dental_Plaque?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_52971846" data-work_id="52971846" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/52971846/Different_Host_Complement_Systems_and_Their_Interactions_with_Saliva_from_Lutzomyia_longipalpis_Diptera_Psychodidae_and_Leishmania_infantum_Promastigotes">Different Host Complement Systems and Their Interactions with Saliva from Lutzomyia longipalpis (Diptera, Psychodidae) and Leishmania infantum Promastigotes</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Background: Lutzomyia longipalpis is the vector of Leishmania infantum in the New World, and its saliva inhibits classical and alternative human complement system pathways. This inhibition is important in protecting the insect´s midgut... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_52971846" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Background: Lutzomyia longipalpis is the vector of Leishmania infantum in the New World, and its saliva inhibits classical and alternative human complement system pathways. This inhibition is important in protecting the insect´s midgut from damage by the complement. L. longipalpis is a promiscuous blood feeder and must be protected against its host's complement. The objective of this study was to investigate the action of salivary complement inhibitors on the sera of different host species, such as dogs, guinea pigs, rats and chickens, at a pH of 7.4 (normal blood pH) and 8.15 (the midgut pH immediately after a blood meal). We also investigated the role of the chicken complement system in Leishmania clearance in the presence and absence of vector saliva. Results: The saliva was capable of inhibiting classical pathways in dogs, guinea pigs and rats at both pHs. The alternative pathway was not inhibited except in dogs at a pH of 8.15. The chicken classical pathway was inhibited only by high concentrations of saliva and it was better inhibited by the midgut contents of sand flies. Neither the saliva nor the midgut contents had any effect on the avian alternative pathway. Fowl sera killed L. infantum promastigotes, even at a low concentration (2%), and the addition of L. longipalpis saliva did not protect the parasites. The high body temperature of chickens (40°C) had no effect on Leishmania viability during our assays. Conclusion: Salivary inhibitors act in a species-specific manner. It is important to determine their effects in the natural hosts of Leishmania infantum because they act on canid and rodent complements but not on chickens (which do not harbour the parasite). Moreover, we concluded that the avian complement system is the probable mechanism through which chickens eliminate Leishmania and that their high body temperature does not influence this parasite.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/52971846" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="742712321f0b1a0f6ab82dcb8102606d" rel="nofollow" data-download="{"attachment_id":69976160,"asset_id":52971846,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/69976160/download_file?st=MTc0MDAzODkzNSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32425769" href="https://independent.academia.edu/RicardoAraujo19">Ricardo Araujo</a><script data-card-contents-for-user="32425769" type="text/json">{"id":32425769,"first_name":"Ricardo","last_name":"Araujo","domain_name":"independent","page_name":"RicardoAraujo19","display_name":"Ricardo Araujo","profile_url":"https://independent.academia.edu/RicardoAraujo19?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_52971846 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="52971846"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 52971846, container: ".js-paper-rank-work_52971846", }); 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$(".js-view-count[data-work-id=52971846]").text(description); $(".js-view-count-work_52971846").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_52971846").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="52971846"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">18</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="48" rel="nofollow" href="https://www.academia.edu/Documents/in/Engineering">Engineering</a>, <script data-card-contents-for-ri="48" type="text/json">{"id":48,"name":"Engineering","url":"https://www.academia.edu/Documents/in/Engineering?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="498" rel="nofollow" href="https://www.academia.edu/Documents/in/Physics">Physics</a>, <script data-card-contents-for-ri="498" type="text/json">{"id":498,"name":"Physics","url":"https://www.academia.edu/Documents/in/Physics?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="523" rel="nofollow" href="https://www.academia.edu/Documents/in/Chemistry">Chemistry</a>, <script data-card-contents-for-ri="523" type="text/json">{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="2705" rel="nofollow" href="https://www.academia.edu/Documents/in/Complement_activation">Complement activation</a><script data-card-contents-for-ri="2705" type="text/json">{"id":2705,"name":"Complement activation","url":"https://www.academia.edu/Documents/in/Complement_activation?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=52971846]'), work: {"id":52971846,"title":"Different Host Complement Systems and Their Interactions with Saliva from Lutzomyia longipalpis (Diptera, Psychodidae) and Leishmania infantum Promastigotes","created_at":"2021-09-20T03:46:23.255-07:00","url":"https://www.academia.edu/52971846/Different_Host_Complement_Systems_and_Their_Interactions_with_Saliva_from_Lutzomyia_longipalpis_Diptera_Psychodidae_and_Leishmania_infantum_Promastigotes?f_ri=344106","dom_id":"work_52971846","summary":"Background: Lutzomyia longipalpis is the vector of Leishmania infantum in the New World, and its saliva inhibits classical and alternative human complement system pathways. This inhibition is important in protecting the insect´s midgut from damage by the complement. L. longipalpis is a promiscuous blood feeder and must be protected against its host's complement. The objective of this study was to investigate the action of salivary complement inhibitors on the sera of different host species, such as dogs, guinea pigs, rats and chickens, at a pH of 7.4 (normal blood pH) and 8.15 (the midgut pH immediately after a blood meal). We also investigated the role of the chicken complement system in Leishmania clearance in the presence and absence of vector saliva. Results: The saliva was capable of inhibiting classical pathways in dogs, guinea pigs and rats at both pHs. The alternative pathway was not inhibited except in dogs at a pH of 8.15. The chicken classical pathway was inhibited only by high concentrations of saliva and it was better inhibited by the midgut contents of sand flies. Neither the saliva nor the midgut contents had any effect on the avian alternative pathway. Fowl sera killed L. infantum promastigotes, even at a low concentration (2%), and the addition of L. longipalpis saliva did not protect the parasites. The high body temperature of chickens (40°C) had no effect on Leishmania viability during our assays. Conclusion: Salivary inhibitors act in a species-specific manner. It is important to determine their effects in the natural hosts of Leishmania infantum because they act on canid and rodent complements but not on chickens (which do not harbour the parasite). Moreover, we concluded that the avian complement system is the probable mechanism through which chickens eliminate Leishmania and that their high body temperature does not influence this parasite.","downloadable_attachments":[{"id":69976160,"asset_id":52971846,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32425769,"first_name":"Ricardo","last_name":"Araujo","domain_name":"independent","page_name":"RicardoAraujo19","display_name":"Ricardo Araujo","profile_url":"https://independent.academia.edu/RicardoAraujo19?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":48,"name":"Engineering","url":"https://www.academia.edu/Documents/in/Engineering?f_ri=344106","nofollow":true},{"id":498,"name":"Physics","url":"https://www.academia.edu/Documents/in/Physics?f_ri=344106","nofollow":true},{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry?f_ri=344106","nofollow":true},{"id":2705,"name":"Complement activation","url":"https://www.academia.edu/Documents/in/Complement_activation?f_ri=344106","nofollow":true},{"id":4987,"name":"Kinetics","url":"https://www.academia.edu/Documents/in/Kinetics?f_ri=344106"},{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=344106"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=344106"},{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary?f_ri=344106"},{"id":52438,"name":"Dogs","url":"https://www.academia.edu/Documents/in/Dogs?f_ri=344106"},{"id":220780,"name":"PLoS one","url":"https://www.academia.edu/Documents/in/PLoS_one?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":375054,"name":"Rats","url":"https://www.academia.edu/Documents/in/Rats?f_ri=344106"},{"id":402759,"name":"Chickens","url":"https://www.academia.edu/Documents/in/Chickens?f_ri=344106"},{"id":652363,"name":"Psychodidae","url":"https://www.academia.edu/Documents/in/Psychodidae?f_ri=344106"},{"id":743643,"name":"Host Pathogen Interactions","url":"https://www.academia.edu/Documents/in/Host_Pathogen_Interactions?f_ri=344106"},{"id":789996,"name":"Leishmania infantum","url":"https://www.academia.edu/Documents/in/Leishmania_infantum?f_ri=344106"},{"id":1137254,"name":"Hydrogen-Ion Concentration","url":"https://www.academia.edu/Documents/in/Hydrogen-Ion_Concentration?f_ri=344106"},{"id":3769209,"name":"Guinea pigs","url":"https://www.academia.edu/Documents/in/Guinea_pigs?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_52152513" data-work_id="52152513" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/52152513/Salivary_cortisol_levels_and_dental_anxiety_in_children_with_attention_deficit_hyperactivity_disorder">Salivary cortisol levels and dental anxiety in children with attention deficit hyperactivity disorder</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/52152513" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa 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Dahllöf","profile_url":"https://independent.academia.edu/G%C3%B6ranDahll%C3%B6f?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":596,"name":"Dentistry","url":"https://www.academia.edu/Documents/in/Dentistry?f_ri=344106","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=344106","nofollow":true},{"id":28850,"name":"Linear models","url":"https://www.academia.edu/Documents/in/Linear_models?f_ri=344106","nofollow":true},{"id":37828,"name":"Behavioral Science","url":"https://www.academia.edu/Documents/in/Behavioral_Science?f_ri=344106","nofollow":true},{"id":279027,"name":"European","url":"https://www.academia.edu/Documents/in/European?f_ri=344106"},{"id":298240,"name":"Dental Anxiety","url":"https://www.academia.edu/Documents/in/Dental_Anxiety?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":584601,"name":"Chi Square Distribution","url":"https://www.academia.edu/Documents/in/Chi_Square_Distribution?f_ri=344106"},{"id":976842,"name":"Salivary Cortisol","url":"https://www.academia.edu/Documents/in/Salivary_Cortisol?f_ri=344106"},{"id":1201074,"name":"Psychological Stress","url":"https://www.academia.edu/Documents/in/Psychological_Stress?f_ri=344106"},{"id":1819399,"name":"Case Control Studies","url":"https://www.academia.edu/Documents/in/Case_Control_Studies?f_ri=344106"},{"id":2526151,"name":"Attention deficit disorder with hyperactivity","url":"https://www.academia.edu/Documents/in/Attention_deficit_disorder_with_hyperactivity?f_ri=344106"},{"id":2754641,"name":"Attention deficit hyperactivity disorder","url":"https://www.academia.edu/Documents/in/Attention_deficit_hyperactivity_disorder-1?f_ri=344106"},{"id":3359206,"name":"hydrocortisone","url":"https://www.academia.edu/Documents/in/hydrocortisone?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_33952023" data-work_id="33952023" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/33952023/Poloxamer_407_microspheres_for_orotransmucosal_drug_delivery_Part_I_formulation_manufacturing_and_characterization">Poloxamer 407 microspheres for orotransmucosal drug delivery. Part I: formulation, manufacturing and characterization</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The two-part article aimed to investigate poloxamer 407-based microspheres as a novel platform for enhancing and controlling the delivery of atenolol across the oromucosal tissue. In the Part I of the work, atenolol-loaded poloxamers 407... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_33952023" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The two-part article aimed to investigate poloxamer 407-based microspheres as a novel platform for enhancing and controlling the delivery of atenolol across the oromucosal tissue. In the Part I of the work, atenolol-loaded poloxamers 407 microparticles were prepared by the solvent free spray congealing technology. This approach was feasible upon the high viscosity of the systems allowing for high loaded (20% w/w) non-aggregated microspheres. Several formulations were studied and the results demonstrated that the drug release patterns, solubility data, mucoadhesion to buccal tissue and gelling properties in saliva could be modified by adding different amount of an amphiphilic polymer-lipid excipient (Gelucire(®) 50/13) to poloxamer 407. Particularly, microspheres based only on poloxamer 407 exhibited very high solubility, mucoadhesive strength and gelling behaviour. To assess their potential as matrix for buccal application, the gelling property and the drug release from tablets obta...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/33952023" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a08bebf225890a7fe016eb690a710861" rel="nofollow" data-download="{"attachment_id":53912602,"asset_id":33952023,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/53912602/download_file?st=MTc0MDAzODkzNSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="63296659" href="https://independent.academia.edu/LuisCarlosUdaetaRodriguez">Luis Carlos Udaeta Rodriguez</a><script data-card-contents-for-user="63296659" type="text/json">{"id":63296659,"first_name":"Luis Carlos","last_name":"Udaeta Rodriguez","domain_name":"independent","page_name":"LuisCarlosUdaetaRodriguez","display_name":"Luis Carlos Udaeta Rodriguez","profile_url":"https://independent.academia.edu/LuisCarlosUdaetaRodriguez?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_33952023 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="33952023"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 33952023, container: ".js-paper-rank-work_33952023", }); 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$(".js-view-count[data-work-id=33952023]").text(description); $(".js-view-count-work_33952023").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_33952023").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="33952023"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">29</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="988" rel="nofollow" href="https://www.academia.edu/Documents/in/Design">Design</a>, <script data-card-contents-for-ri="988" type="text/json">{"id":988,"name":"Design","url":"https://www.academia.edu/Documents/in/Design?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="2979" rel="nofollow" href="https://www.academia.edu/Documents/in/Manufacturing">Manufacturing</a>, <script data-card-contents-for-ri="2979" type="text/json">{"id":2979,"name":"Manufacturing","url":"https://www.academia.edu/Documents/in/Manufacturing?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="10655" rel="nofollow" href="https://www.academia.edu/Documents/in/Scanning_Electron_Microscopy">Scanning Electron Microscopy</a>, <script data-card-contents-for-ri="10655" type="text/json">{"id":10655,"name":"Scanning Electron Microscopy","url":"https://www.academia.edu/Documents/in/Scanning_Electron_Microscopy?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="11222" rel="nofollow" href="https://www.academia.edu/Documents/in/Powder_Diffraction">Powder Diffraction</a><script data-card-contents-for-ri="11222" type="text/json">{"id":11222,"name":"Powder Diffraction","url":"https://www.academia.edu/Documents/in/Powder_Diffraction?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=33952023]'), work: {"id":33952023,"title":"Poloxamer 407 microspheres for orotransmucosal drug delivery. Part I: formulation, manufacturing and characterization","created_at":"2017-07-19T14:36:25.350-07:00","url":"https://www.academia.edu/33952023/Poloxamer_407_microspheres_for_orotransmucosal_drug_delivery_Part_I_formulation_manufacturing_and_characterization?f_ri=344106","dom_id":"work_33952023","summary":"The two-part article aimed to investigate poloxamer 407-based microspheres as a novel platform for enhancing and controlling the delivery of atenolol across the oromucosal tissue. In the Part I of the work, atenolol-loaded poloxamers 407 microparticles were prepared by the solvent free spray congealing technology. This approach was feasible upon the high viscosity of the systems allowing for high loaded (20% w/w) non-aggregated microspheres. Several formulations were studied and the results demonstrated that the drug release patterns, solubility data, mucoadhesion to buccal tissue and gelling properties in saliva could be modified by adding different amount of an amphiphilic polymer-lipid excipient (Gelucire(®) 50/13) to poloxamer 407. Particularly, microspheres based only on poloxamer 407 exhibited very high solubility, mucoadhesive strength and gelling behaviour. To assess their potential as matrix for buccal application, the gelling property and the drug release from tablets obta...","downloadable_attachments":[{"id":53912602,"asset_id":33952023,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":63296659,"first_name":"Luis Carlos","last_name":"Udaeta Rodriguez","domain_name":"independent","page_name":"LuisCarlosUdaetaRodriguez","display_name":"Luis Carlos Udaeta Rodriguez","profile_url":"https://independent.academia.edu/LuisCarlosUdaetaRodriguez?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":988,"name":"Design","url":"https://www.academia.edu/Documents/in/Design?f_ri=344106","nofollow":true},{"id":2979,"name":"Manufacturing","url":"https://www.academia.edu/Documents/in/Manufacturing?f_ri=344106","nofollow":true},{"id":10655,"name":"Scanning Electron Microscopy","url":"https://www.academia.edu/Documents/in/Scanning_Electron_Microscopy?f_ri=344106","nofollow":true},{"id":11222,"name":"Powder Diffraction","url":"https://www.academia.edu/Documents/in/Powder_Diffraction?f_ri=344106","nofollow":true},{"id":11257,"name":"Drug delivery","url":"https://www.academia.edu/Documents/in/Drug_delivery?f_ri=344106"},{"id":23390,"name":"Pharmaceutical Chemistry","url":"https://www.academia.edu/Documents/in/Pharmaceutical_Chemistry?f_ri=344106"},{"id":41745,"name":"Pharmaceutics","url":"https://www.academia.edu/Documents/in/Pharmaceutics?f_ri=344106"},{"id":57518,"name":"Conception","url":"https://www.academia.edu/Documents/in/Conception?f_ri=344106"},{"id":78753,"name":"Differential scanning calorimetry","url":"https://www.academia.edu/Documents/in/Differential_scanning_calorimetry?f_ri=344106"},{"id":83972,"name":"Permeability","url":"https://www.academia.edu/Documents/in/Permeability?f_ri=344106"},{"id":109384,"name":"Viscosity","url":"https://www.academia.edu/Documents/in/Viscosity?f_ri=344106"},{"id":136801,"name":"Fabrication","url":"https://www.academia.edu/Documents/in/Fabrication?f_ri=344106"},{"id":176756,"name":"FORMULATION","url":"https://www.academia.edu/Documents/in/FORMULATION?f_ri=344106"},{"id":205584,"name":"Solubility","url":"https://www.academia.edu/Documents/in/Solubility?f_ri=344106"},{"id":298289,"name":"Microparticles","url":"https://www.academia.edu/Documents/in/Microparticles?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":385863,"name":"Mouth mucosa","url":"https://www.academia.edu/Documents/in/Mouth_mucosa?f_ri=344106"},{"id":386527,"name":"X ray diffraction","url":"https://www.academia.edu/Documents/in/X_ray_diffraction?f_ri=344106"},{"id":390245,"name":"Particle Size","url":"https://www.academia.edu/Documents/in/Particle_Size?f_ri=344106"},{"id":398650,"name":"Fourier transform infrared spectroscopy","url":"https://www.academia.edu/Documents/in/Fourier_transform_infrared_spectroscopy?f_ri=344106"},{"id":440924,"name":"Surface Properties","url":"https://www.academia.edu/Documents/in/Surface_Properties?f_ri=344106"},{"id":469575,"name":"Solid State","url":"https://www.academia.edu/Documents/in/Solid_State?f_ri=344106"},{"id":476883,"name":"Tablets","url":"https://www.academia.edu/Documents/in/Tablets?f_ri=344106"},{"id":556132,"name":"Microsphere","url":"https://www.academia.edu/Documents/in/Microsphere?f_ri=344106"},{"id":794074,"name":"Microspheres","url":"https://www.academia.edu/Documents/in/Microspheres?f_ri=344106"},{"id":1031068,"name":"Drug Carriers","url":"https://www.academia.edu/Documents/in/Drug_Carriers?f_ri=344106"},{"id":1135812,"name":"Drug Compounding","url":"https://www.academia.edu/Documents/in/Drug_Compounding?f_ri=344106"},{"id":2033993,"name":"Poloxamer","url":"https://www.academia.edu/Documents/in/Poloxamer?f_ri=344106"},{"id":2380004,"name":"Pharmaceutical preparations","url":"https://www.academia.edu/Documents/in/Pharmaceutical_preparations?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_31117052" data-work_id="31117052" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/31117052/Olive_oil_phenolic_compounds_affect_the_release_of_aroma_compounds">Olive oil phenolic compounds affect the release of aroma compounds</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Twelve aroma compounds were monitored and quantified by dynamic headspace analysis after their addition in refined olive oil model systems with extra virgin olive oil (EVOO) biophenols to simulate EVOO aroma. The influence of polyphenols... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_31117052" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Twelve aroma compounds were monitored and quantified by dynamic headspace analysis after their addition in refined olive oil model systems with extra virgin olive oil (EVOO) biophenols to simulate EVOO aroma. The influence of polyphenols on aroma release was studied under simulated mouth conditions by using human saliva, and SPME-GC/MS analysis. While few differences were observed in orthonasal assay (without saliva), interesting results were obtained for retronasal aroma. Biophenols caused generally the lowest headspace release of almost all volatile compounds. However, only ethyl esters and linalool concentrations were significantly lower in retronasal than orthonasal assay. Saliva also caused higher concentration of hexanal, probably due to hydroperoxide lyase (HPL) action on linoleyl hydroperoxides. Epicatechin was compared to EVOO phenolics and the behaviour was dramatically different, likely to be due to salivary protein-tannin binding interactions, which influenced aroma headspace release. These results were also confirmed using two extra virgin olive oils.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/31117052" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="dd5cd053222102c1332d7b45676e542e" rel="nofollow" data-download="{"attachment_id":51552765,"asset_id":31117052,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/51552765/download_file?st=MTc0MDAzODkzNSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="59431356" href="https://independent.academia.edu/AlessandroGenovese1">Alessandro Genovese</a><script data-card-contents-for-user="59431356" type="text/json">{"id":59431356,"first_name":"Alessandro","last_name":"Genovese","domain_name":"independent","page_name":"AlessandroGenovese1","display_name":"Alessandro Genovese","profile_url":"https://independent.academia.edu/AlessandroGenovese1?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_31117052 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="31117052"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 31117052, container: ".js-paper-rank-work_31117052", }); });</script></li><li class="js-percentile-work_31117052 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 31117052; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_31117052"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_31117052 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="31117052"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 31117052; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=31117052]").text(description); $(".js-view-count-work_31117052").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_31117052").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="31117052"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">18</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="1040" rel="nofollow" href="https://www.academia.edu/Documents/in/Food_Science">Food Science</a>, <script data-card-contents-for-ri="1040" type="text/json">{"id":1040,"name":"Food Science","url":"https://www.academia.edu/Documents/in/Food_Science?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="16137" rel="nofollow" href="https://www.academia.edu/Documents/in/Food_Chemistry">Food Chemistry</a>, <script data-card-contents-for-ri="16137" type="text/json">{"id":16137,"name":"Food Chemistry","url":"https://www.academia.edu/Documents/in/Food_Chemistry?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="23572" rel="nofollow" href="https://www.academia.edu/Documents/in/Olive_Oil">Olive Oil</a>, <script data-card-contents-for-ri="23572" type="text/json">{"id":23572,"name":"Olive Oil","url":"https://www.academia.edu/Documents/in/Olive_Oil?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="28235" rel="nofollow" href="https://www.academia.edu/Documents/in/Multidisciplinary">Multidisciplinary</a><script data-card-contents-for-ri="28235" type="text/json">{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=31117052]'), work: {"id":31117052,"title":"Olive oil phenolic compounds affect the release of aroma compounds","created_at":"2017-01-30T02:38:47.242-08:00","url":"https://www.academia.edu/31117052/Olive_oil_phenolic_compounds_affect_the_release_of_aroma_compounds?f_ri=344106","dom_id":"work_31117052","summary":"Twelve aroma compounds were monitored and quantified by dynamic headspace analysis after their addition in refined olive oil model systems with extra virgin olive oil (EVOO) biophenols to simulate EVOO aroma. The influence of polyphenols on aroma release was studied under simulated mouth conditions by using human saliva, and SPME-GC/MS analysis. While few differences were observed in orthonasal assay (without saliva), interesting results were obtained for retronasal aroma. Biophenols caused generally the lowest headspace release of almost all volatile compounds. However, only ethyl esters and linalool concentrations were significantly lower in retronasal than orthonasal assay. Saliva also caused higher concentration of hexanal, probably due to hydroperoxide lyase (HPL) action on linoleyl hydroperoxides. Epicatechin was compared to EVOO phenolics and the behaviour was dramatically different, likely to be due to salivary protein-tannin binding interactions, which influenced aroma headspace release. These results were also confirmed using two extra virgin olive oils.","downloadable_attachments":[{"id":51552765,"asset_id":31117052,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":59431356,"first_name":"Alessandro","last_name":"Genovese","domain_name":"independent","page_name":"AlessandroGenovese1","display_name":"Alessandro Genovese","profile_url":"https://independent.academia.edu/AlessandroGenovese1?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":1040,"name":"Food Science","url":"https://www.academia.edu/Documents/in/Food_Science?f_ri=344106","nofollow":true},{"id":16137,"name":"Food Chemistry","url":"https://www.academia.edu/Documents/in/Food_Chemistry?f_ri=344106","nofollow":true},{"id":23572,"name":"Olive Oil","url":"https://www.academia.edu/Documents/in/Olive_Oil?f_ri=344106","nofollow":true},{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary?f_ri=344106","nofollow":true},{"id":28850,"name":"Linear models","url":"https://www.academia.edu/Documents/in/Linear_models?f_ri=344106"},{"id":34478,"name":"Food Science and Technology","url":"https://www.academia.edu/Documents/in/Food_Science_and_Technology?f_ri=344106"},{"id":70043,"name":"Polyphenols","url":"https://www.academia.edu/Documents/in/Polyphenols?f_ri=344106"},{"id":70274,"name":"Olive and Olive Oil Technology","url":"https://www.academia.edu/Documents/in/Olive_and_Olive_Oil_Technology?f_ri=344106"},{"id":93418,"name":"Volatile Organic Compounds","url":"https://www.academia.edu/Documents/in/Volatile_Organic_Compounds?f_ri=344106"},{"id":225940,"name":"Phenolics","url":"https://www.academia.edu/Documents/in/Phenolics?f_ri=344106"},{"id":251731,"name":"GC","url":"https://www.academia.edu/Documents/in/GC?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":347949,"name":"Phenolic Compounds","url":"https://www.academia.edu/Documents/in/Phenolic_Compounds?f_ri=344106"},{"id":357416,"name":"Odors","url":"https://www.academia.edu/Documents/in/Odors?f_ri=344106"},{"id":439989,"name":"Food Aroma Compounds","url":"https://www.academia.edu/Documents/in/Food_Aroma_Compounds?f_ri=344106"},{"id":510521,"name":"Flavours and Fragrances","url":"https://www.academia.edu/Documents/in/Flavours_and_Fragrances?f_ri=344106"},{"id":529560,"name":"Gas Chromatography/mass Spectrometry","url":"https://www.academia.edu/Documents/in/Gas_Chromatography_mass_Spectrometry?f_ri=344106"},{"id":2230327,"name":"Aldehydes","url":"https://www.academia.edu/Documents/in/Aldehydes?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_1361368" data-work_id="1361368" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/1361368/Kinetic_spectrophotometric_method_for_trace_determination_of_thiocyanate_based_on_its_inhibitory_effect">Kinetic spectrophotometric method for trace determination of thiocyanate based on its inhibitory effect</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">A kinetic spectrophotometric method for the determination of thiocyanate, based on its inhibitory effect on silver(I) catalyzed substitution of cyanide ion, by phenylhydrazine in hexacyanoferrate(II) is described. Thiocyanate ions form... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_1361368" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">A kinetic spectrophotometric method for the determination of thiocyanate, based on its inhibitory effect on silver(I) catalyzed substitution of cyanide ion, by phenylhydrazine in hexacyanoferrate(II) is described. Thiocyanate ions form strong complexes with silver(I) catalyst which is used as the basis for its determination at trace level. The progress of reaction was monitored, spectrophotometrically, at 488 nm max of [Fe(CN) 5 PhNHNH 2 ] 3− , complex) under the optimum reaction conditions at: 2.5 × 10 −3 M [Fe(CN) 6 ] 4− , 1.0 × 10 −3 M [PhNHNH 2 ], 8.0 × 10 −7 M [Ag + ], pH 2.8 ± 0.02, ionic strength ( ) 0.02 M (KNO 3 ) and temperature 30 ± 0.1 • C. A linear relationship obtained between absorbance (measured at 488 nm at different times) and inhibitor concentration, under specified conditions, has been used for the determination of [thiocyanate] in the range of 0.8-8.0 × 10 −8 M with a detection limit of 2 × 10 −9 M. The standard deviation and percentage error have been calculated and reported with each datum. A most plausible mechanistic scheme has been proposed for the reaction. The values of equilibrium constants for complex formation between catalyst-inhibitor (K CI ), catalyst-substrate (K s ) and Michaelis-Menten constant (K m ) have been computed from the kinetic data. The influence of possible interference by major cations and anions on the determination of thiocyanate and their limits has been investigated.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/1361368" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="f2ef8454daa9e7c9c9f5d6ffb38cad0b" rel="nofollow" data-download="{"attachment_id":51011486,"asset_id":1361368,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/51011486/download_file?st=MTc0MDAzODkzNSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="1192165" href="https://lkouniv.academia.edu/AbhasAsthana">Abhas Asthana</a><script data-card-contents-for-user="1192165" type="text/json">{"id":1192165,"first_name":"Abhas","last_name":"Asthana","domain_name":"lkouniv","page_name":"AbhasAsthana","display_name":"Abhas Asthana","profile_url":"https://lkouniv.academia.edu/AbhasAsthana?f_ri=344106","photo":"https://0.academia-photos.com/1192165/426467/526656/s65_abhas.asthana.jpg"}</script></span></span></li><li class="js-paper-rank-work_1361368 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="1361368"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 1361368, container: ".js-paper-rank-work_1361368", }); });</script></li><li class="js-percentile-work_1361368 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 1361368; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_1361368"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_1361368 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="1361368"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 1361368; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=1361368]").text(description); $(".js-view-count-work_1361368").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_1361368").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="1361368"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">14</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="524" rel="nofollow" href="https://www.academia.edu/Documents/in/Analytical_Chemistry">Analytical Chemistry</a>, <script data-card-contents-for-ri="524" type="text/json">{"id":524,"name":"Analytical Chemistry","url":"https://www.academia.edu/Documents/in/Analytical_Chemistry?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="2215" rel="nofollow" href="https://www.academia.edu/Documents/in/Water">Water</a>, <script data-card-contents-for-ri="2215" type="text/json">{"id":2215,"name":"Water","url":"https://www.academia.edu/Documents/in/Water?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4749" rel="nofollow" href="https://www.academia.edu/Documents/in/Catalysis">Catalysis</a>, <script data-card-contents-for-ri="4749" type="text/json">{"id":4749,"name":"Catalysis","url":"https://www.academia.edu/Documents/in/Catalysis?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4987" rel="nofollow" href="https://www.academia.edu/Documents/in/Kinetics">Kinetics</a><script data-card-contents-for-ri="4987" type="text/json">{"id":4987,"name":"Kinetics","url":"https://www.academia.edu/Documents/in/Kinetics?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=1361368]'), work: {"id":1361368,"title":"Kinetic spectrophotometric method for trace determination of thiocyanate based on its inhibitory effect","created_at":"2012-02-08T15:02:49.873-08:00","url":"https://www.academia.edu/1361368/Kinetic_spectrophotometric_method_for_trace_determination_of_thiocyanate_based_on_its_inhibitory_effect?f_ri=344106","dom_id":"work_1361368","summary":"A kinetic spectrophotometric method for the determination of thiocyanate, based on its inhibitory effect on silver(I) catalyzed substitution of cyanide ion, by phenylhydrazine in hexacyanoferrate(II) is described. Thiocyanate ions form strong complexes with silver(I) catalyst which is used as the basis for its determination at trace level. The progress of reaction was monitored, spectrophotometrically, at 488 nm max of [Fe(CN) 5 PhNHNH 2 ] 3− , complex) under the optimum reaction conditions at: 2.5 × 10 −3 M [Fe(CN) 6 ] 4− , 1.0 × 10 −3 M [PhNHNH 2 ], 8.0 × 10 −7 M [Ag + ], pH 2.8 ± 0.02, ionic strength ( ) 0.02 M (KNO 3 ) and temperature 30 ± 0.1 • C. A linear relationship obtained between absorbance (measured at 488 nm at different times) and inhibitor concentration, under specified conditions, has been used for the determination of [thiocyanate] in the range of 0.8-8.0 × 10 −8 M with a detection limit of 2 × 10 −9 M. The standard deviation and percentage error have been calculated and reported with each datum. A most plausible mechanistic scheme has been proposed for the reaction. The values of equilibrium constants for complex formation between catalyst-inhibitor (K CI ), catalyst-substrate (K s ) and Michaelis-Menten constant (K m ) have been computed from the kinetic data. The influence of possible interference by major cations and anions on the determination of thiocyanate and their limits has been investigated.","downloadable_attachments":[{"id":51011486,"asset_id":1361368,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":1192165,"first_name":"Abhas","last_name":"Asthana","domain_name":"lkouniv","page_name":"AbhasAsthana","display_name":"Abhas Asthana","profile_url":"https://lkouniv.academia.edu/AbhasAsthana?f_ri=344106","photo":"https://0.academia-photos.com/1192165/426467/526656/s65_abhas.asthana.jpg"}],"research_interests":[{"id":524,"name":"Analytical Chemistry","url":"https://www.academia.edu/Documents/in/Analytical_Chemistry?f_ri=344106","nofollow":true},{"id":2215,"name":"Water","url":"https://www.academia.edu/Documents/in/Water?f_ri=344106","nofollow":true},{"id":4749,"name":"Catalysis","url":"https://www.academia.edu/Documents/in/Catalysis?f_ri=344106","nofollow":true},{"id":4987,"name":"Kinetics","url":"https://www.academia.edu/Documents/in/Kinetics?f_ri=344106","nofollow":true},{"id":69841,"name":"Standard Deviation","url":"https://www.academia.edu/Documents/in/Standard_Deviation?f_ri=344106"},{"id":133177,"name":"Temperature","url":"https://www.academia.edu/Documents/in/Temperature?f_ri=344106"},{"id":160656,"name":"Potassium","url":"https://www.academia.edu/Documents/in/Potassium?f_ri=344106"},{"id":178351,"name":"Spectrophotometry","url":"https://www.academia.edu/Documents/in/Spectrophotometry?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":903511,"name":"Cyanides","url":"https://www.academia.edu/Documents/in/Cyanides?f_ri=344106"},{"id":970774,"name":"Ionic Strength","url":"https://www.academia.edu/Documents/in/Ionic_Strength?f_ri=344106"},{"id":1137254,"name":"Hydrogen-Ion Concentration","url":"https://www.academia.edu/Documents/in/Hydrogen-Ion_Concentration?f_ri=344106"},{"id":1352490,"name":"Oxidants","url":"https://www.academia.edu/Documents/in/Oxidants?f_ri=344106"},{"id":1458665,"name":"Equilibrium Constant","url":"https://www.academia.edu/Documents/in/Equilibrium_Constant?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_28211258 coauthored" data-work_id="28211258" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/28211258/Differential_effects_of_active_versus_passive_coping_on_secretory_immunity">Differential effects of active versus passive coping on secretory immunity</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">This study examined the acute immunological effects of two laboratory stressors, expected to evoke distinct patterns of cardiac autonomic activity; namely an "active coping" time-paced memory test, and a "passive coping" stressful video... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_28211258" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">This study examined the acute immunological effects of two laboratory stressors, expected to evoke distinct patterns of cardiac autonomic activity; namely an "active coping" time-paced memory test, and a "passive coping" stressful video showing surgical operations. We measured salivary S-IgA, IgA-subclasses~IgA1, IgA2!, and secretory component SC!. SC is responsible for the transport of S-IgA across the epithelium, and thus a rate-determining step in S-IgA secretion. Thirty-two male undergraduates were subjected to both stressors and a control video~a didactic television program!. The memory test induced a typical "fight-flight" response, characterized by increases in heart rate and blood pressure in association with a decrease in cardiac preejection period~PEP! and vagal tone. The surgical video produced a "conservation-withdrawal"-like response, characterized by an enhanced vagal tone, a decrease in heart rate, and a moderate sympathetic coactivation~as indicated by a shortened PEP and an increased systolic pressure!. The memory test induced an increase in the concentration and, to a lesser extent, in the output of S-IgA, IgA1, and SC. The output of IgA2 was not significantly affected. For the surgical video, a different pattern emerged: During stressor exposure S-IgA remained unaffected, against the background of a small increase in SC output. However, 10 min after the surgical video S-IgA levels had decreased. This decrease in S-IgA was paralleled by a decrease in IgA1, but not IgA2. We conclude that acute stress can have both enhancing and suppressive effects on secretory immunity, the IgA1 subclass in particular. The mechanisms that underlie these divergent responses may include stressor-specific patterns of autonomic activation. ! were very helpful by providing detailed information on their secretory component ELISA. We are grateful to Marjolein Turkenburg and Karin Hartog for their devoted assistance in performing the biochemical analyses.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/28211258" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="d692b6f4aa4c905ae367e419a5298f9b" rel="nofollow" data-download="{"attachment_id":48522329,"asset_id":28211258,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48522329/download_file?st=MTc0MDAzODkzNSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="52874266" href="https://independent.academia.edu/JosBosch">Jos Bosch</a><script data-card-contents-for-user="52874266" type="text/json">{"id":52874266,"first_name":"Jos","last_name":"Bosch","domain_name":"independent","page_name":"JosBosch","display_name":"Jos Bosch","profile_url":"https://independent.academia.edu/JosBosch?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-28211258">+1</span><div class="hidden js-additional-users-28211258"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/EcoDeGeus">Eco De Geus</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-28211258'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-28211258').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_28211258 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="28211258"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 28211258, container: ".js-paper-rank-work_28211258", }); });</script></li><li class="js-percentile-work_28211258 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 28211258; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_28211258"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_28211258 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="28211258"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 28211258; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=28211258]").text(description); $(".js-view-count-work_28211258").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_28211258").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="28211258"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">11</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="1026" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychophysiology">Psychophysiology</a>, <script data-card-contents-for-ri="1026" type="text/json">{"id":1026,"name":"Psychophysiology","url":"https://www.academia.edu/Documents/in/Psychophysiology?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4515" rel="nofollow" href="https://www.academia.edu/Documents/in/PSYCHONEUROIMMUNOLOGY">PSYCHONEUROIMMUNOLOGY</a>, <script data-card-contents-for-ri="4515" type="text/json">{"id":4515,"name":"PSYCHONEUROIMMUNOLOGY","url":"https://www.academia.edu/Documents/in/PSYCHONEUROIMMUNOLOGY?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="47884" rel="nofollow" href="https://www.academia.edu/Documents/in/Biological_Sciences">Biological Sciences</a><script data-card-contents-for-ri="47884" type="text/json">{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=28211258]'), work: {"id":28211258,"title":"Differential effects of active versus passive coping on secretory immunity","created_at":"2016-09-02T12:51:16.166-07:00","url":"https://www.academia.edu/28211258/Differential_effects_of_active_versus_passive_coping_on_secretory_immunity?f_ri=344106","dom_id":"work_28211258","summary":"This study examined the acute immunological effects of two laboratory stressors, expected to evoke distinct patterns of cardiac autonomic activity; namely an \"active coping\" time-paced memory test, and a \"passive coping\" stressful video showing surgical operations. We measured salivary S-IgA, IgA-subclasses~IgA1, IgA2!, and secretory component SC!. SC is responsible for the transport of S-IgA across the epithelium, and thus a rate-determining step in S-IgA secretion. Thirty-two male undergraduates were subjected to both stressors and a control video~a didactic television program!. The memory test induced a typical \"fight-flight\" response, characterized by increases in heart rate and blood pressure in association with a decrease in cardiac preejection period~PEP! and vagal tone. The surgical video produced a \"conservation-withdrawal\"-like response, characterized by an enhanced vagal tone, a decrease in heart rate, and a moderate sympathetic coactivation~as indicated by a shortened PEP and an increased systolic pressure!. The memory test induced an increase in the concentration and, to a lesser extent, in the output of S-IgA, IgA1, and SC. The output of IgA2 was not significantly affected. For the surgical video, a different pattern emerged: During stressor exposure S-IgA remained unaffected, against the background of a small increase in SC output. However, 10 min after the surgical video S-IgA levels had decreased. This decrease in S-IgA was paralleled by a decrease in IgA1, but not IgA2. We conclude that acute stress can have both enhancing and suppressive effects on secretory immunity, the IgA1 subclass in particular. The mechanisms that underlie these divergent responses may include stressor-specific patterns of autonomic activation. ! were very helpful by providing detailed information on their secretory component ELISA. We are grateful to Marjolein Turkenburg and Karin Hartog for their devoted assistance in performing the biochemical analyses.","downloadable_attachments":[{"id":48522329,"asset_id":28211258,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":52874266,"first_name":"Jos","last_name":"Bosch","domain_name":"independent","page_name":"JosBosch","display_name":"Jos Bosch","profile_url":"https://independent.academia.edu/JosBosch?f_ri=344106","photo":"/images/s65_no_pic.png"},{"id":53217813,"first_name":"Eco De","last_name":"Geus","domain_name":"independent","page_name":"EcoDeGeus","display_name":"Eco De Geus","profile_url":"https://independent.academia.edu/EcoDeGeus?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":1026,"name":"Psychophysiology","url":"https://www.academia.edu/Documents/in/Psychophysiology?f_ri=344106","nofollow":true},{"id":4515,"name":"PSYCHONEUROIMMUNOLOGY","url":"https://www.academia.edu/Documents/in/PSYCHONEUROIMMUNOLOGY?f_ri=344106","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=344106","nofollow":true},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=344106","nofollow":true},{"id":74347,"name":"Hemodynamics","url":"https://www.academia.edu/Documents/in/Hemodynamics?f_ri=344106"},{"id":131298,"name":"Heart rate","url":"https://www.academia.edu/Documents/in/Heart_rate?f_ri=344106"},{"id":224454,"name":"Cardiovascular Reactivity","url":"https://www.academia.edu/Documents/in/Cardiovascular_Reactivity?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":1126675,"name":"Memory Testing","url":"https://www.academia.edu/Documents/in/Memory_Testing?f_ri=344106"},{"id":2016105,"name":"Acute stress","url":"https://www.academia.edu/Documents/in/Acute_stress?f_ri=344106"},{"id":2483297,"name":"Immunoglobulin A","url":"https://www.academia.edu/Documents/in/Immunoglobulin_A?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_12922946" data-work_id="12922946" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/12922946/Diagnostic_values_of_parasite_specific_antibody_detections_in_saliva_and_urine_in_comparison_with_serum_in_opisthorchiasis">Diagnostic values of parasite-specific antibody detections in saliva and urine in comparison with serum in opisthorchiasis</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Infection by the liver fluke (Opisthorchis viverrini) causes hepatobiliary disease and bile duct cancer (cholangiocarcinoma, CCA) in endemic areas in Southeast Asia. Measurements of humoral immune response particularly parasite-specific... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_12922946" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Infection by the liver fluke (Opisthorchis viverrini) causes hepatobiliary disease and bile duct cancer (cholangiocarcinoma, CCA) in endemic areas in Southeast Asia. Measurements of humoral immune response particularly parasite-specific antibodies are useful not only for serodiagnosis but they have been implicated as risk factors of CCA. In this study, we used indirect Enzyme Immunosorbent Assay (ELISA) to measure O. viverrini-specific immunoglobulins in serum, urine and saliva and assessed efficacies in diagnosis of opisthorchiasis and evaluated the relationship of antibodies among clinical specimens in a sample population in endemic areas in Khon Kaen, Thailand. By employing the Receiver Operation Characteristics (ROC) analysis, diagnostic efficacy based upon the area under the curve (AUC) revealed that serum, salivary IgG and IgA performed better than urine for diagnosis of opisthorchiasis. Seropositive cases were found in both parasite egg-negative as well as O. viverrini egg-positive groups. The levels of serum IgG correlated with intensity of O. viverrini infection (P b 0.05). Diagnostic sensitivities based on serum and salivary IgG, IgA also positively associated with the intensity of infection. Correlations between serum antibodies and those in saliva were found to be greater in egg-negative than egg-positive individuals for O. viverrini. Our findings indicated a complex interrelation between antibody responses in different clinical specimens triggered by liver fluke infection. More comprehensive examinations are needed to determine the potential utility of salivary antibody detection which, in combination with the conventional fecal examination method, may better assist in the identification of individuals with opisthorchiasis. Furthermore, it may provide a better indicator of the risk of disease, particularly CCA.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/12922946" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="3b1e4c6fdab109a9d1aa9fd93c28e379" rel="nofollow" data-download="{"attachment_id":45845526,"asset_id":12922946,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45845526/download_file?st=MTc0MDAzODkzNSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32096032" href="https://independent.academia.edu/EimornMairiang">Eimorn Mairiang</a><script data-card-contents-for-user="32096032" type="text/json">{"id":32096032,"first_name":"Eimorn","last_name":"Mairiang","domain_name":"independent","page_name":"EimornMairiang","display_name":"Eimorn Mairiang","profile_url":"https://independent.academia.edu/EimornMairiang?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_12922946 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="12922946"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 12922946, container: ".js-paper-rank-work_12922946", }); });</script></li><li class="js-percentile-work_12922946 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 12922946; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_12922946"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_12922946 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="12922946"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 12922946; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=12922946]").text(description); $(".js-view-count-work_12922946").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_12922946").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="12922946"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">23</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="159" rel="nofollow" href="https://www.academia.edu/Documents/in/Microbiology">Microbiology</a>, <script data-card-contents-for-ri="159" type="text/json">{"id":159,"name":"Microbiology","url":"https://www.academia.edu/Documents/in/Microbiology?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="164" rel="nofollow" href="https://www.academia.edu/Documents/in/Parasitology">Parasitology</a>, <script data-card-contents-for-ri="164" type="text/json">{"id":164,"name":"Parasitology","url":"https://www.academia.edu/Documents/in/Parasitology?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6746" rel="nofollow" href="https://www.academia.edu/Documents/in/Southeast_Asia">Southeast Asia</a>, <script data-card-contents-for-ri="6746" type="text/json">{"id":6746,"name":"Southeast Asia","url":"https://www.academia.edu/Documents/in/Southeast_Asia?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6947" rel="nofollow" href="https://www.academia.edu/Documents/in/Medical_Microbiology">Medical Microbiology</a><script data-card-contents-for-ri="6947" type="text/json">{"id":6947,"name":"Medical Microbiology","url":"https://www.academia.edu/Documents/in/Medical_Microbiology?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=12922946]'), work: {"id":12922946,"title":"Diagnostic values of parasite-specific antibody detections in saliva and urine in comparison with serum in opisthorchiasis","created_at":"2015-06-11T05:53:35.822-07:00","url":"https://www.academia.edu/12922946/Diagnostic_values_of_parasite_specific_antibody_detections_in_saliva_and_urine_in_comparison_with_serum_in_opisthorchiasis?f_ri=344106","dom_id":"work_12922946","summary":"Infection by the liver fluke (Opisthorchis viverrini) causes hepatobiliary disease and bile duct cancer (cholangiocarcinoma, CCA) in endemic areas in Southeast Asia. Measurements of humoral immune response particularly parasite-specific antibodies are useful not only for serodiagnosis but they have been implicated as risk factors of CCA. In this study, we used indirect Enzyme Immunosorbent Assay (ELISA) to measure O. viverrini-specific immunoglobulins in serum, urine and saliva and assessed efficacies in diagnosis of opisthorchiasis and evaluated the relationship of antibodies among clinical specimens in a sample population in endemic areas in Khon Kaen, Thailand. By employing the Receiver Operation Characteristics (ROC) analysis, diagnostic efficacy based upon the area under the curve (AUC) revealed that serum, salivary IgG and IgA performed better than urine for diagnosis of opisthorchiasis. Seropositive cases were found in both parasite egg-negative as well as O. viverrini egg-positive groups. The levels of serum IgG correlated with intensity of O. viverrini infection (P b 0.05). Diagnostic sensitivities based on serum and salivary IgG, IgA also positively associated with the intensity of infection. Correlations between serum antibodies and those in saliva were found to be greater in egg-negative than egg-positive individuals for O. viverrini. Our findings indicated a complex interrelation between antibody responses in different clinical specimens triggered by liver fluke infection. More comprehensive examinations are needed to determine the potential utility of salivary antibody detection which, in combination with the conventional fecal examination method, may better assist in the identification of individuals with opisthorchiasis. Furthermore, it may provide a better indicator of the risk of disease, particularly CCA.","downloadable_attachments":[{"id":45845526,"asset_id":12922946,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32096032,"first_name":"Eimorn","last_name":"Mairiang","domain_name":"independent","page_name":"EimornMairiang","display_name":"Eimorn Mairiang","profile_url":"https://independent.academia.edu/EimornMairiang?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":159,"name":"Microbiology","url":"https://www.academia.edu/Documents/in/Microbiology?f_ri=344106","nofollow":true},{"id":164,"name":"Parasitology","url":"https://www.academia.edu/Documents/in/Parasitology?f_ri=344106","nofollow":true},{"id":6746,"name":"Southeast Asia","url":"https://www.academia.edu/Documents/in/Southeast_Asia?f_ri=344106","nofollow":true},{"id":6947,"name":"Medical Microbiology","url":"https://www.academia.edu/Documents/in/Medical_Microbiology?f_ri=344106","nofollow":true},{"id":10096,"name":"Thailand","url":"https://www.academia.edu/Documents/in/Thailand?f_ri=344106"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=344106"},{"id":194916,"name":"ROC Curve","url":"https://www.academia.edu/Documents/in/ROC_Curve?f_ri=344106"},{"id":231661,"name":"Enzyme","url":"https://www.academia.edu/Documents/in/Enzyme?f_ri=344106"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":403821,"name":"Cholangiocarcinoma","url":"https://www.academia.edu/Documents/in/Cholangiocarcinoma?f_ri=344106"},{"id":469102,"name":"Feces","url":"https://www.academia.edu/Documents/in/Feces?f_ri=344106"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=344106"},{"id":644860,"name":"Veterinary Sciences","url":"https://www.academia.edu/Documents/in/Veterinary_Sciences?f_ri=344106"},{"id":819116,"name":"Formaldehyde","url":"https://www.academia.edu/Documents/in/Formaldehyde?f_ri=344106"},{"id":901876,"name":"Sensitivity and Specificity","url":"https://www.academia.edu/Documents/in/Sensitivity_and_Specificity?f_ri=344106"},{"id":1141485,"name":"Area Under the Curve","url":"https://www.academia.edu/Documents/in/Area_Under_the_Curve?f_ri=344106"},{"id":1272906,"name":"Enzyme Linked Immunosorbent Assay","url":"https://www.academia.edu/Documents/in/Enzyme_Linked_Immunosorbent_Assay?f_ri=344106"},{"id":1309706,"name":"Area Under Curve","url":"https://www.academia.edu/Documents/in/Area_Under_Curve?f_ri=344106"},{"id":1312086,"name":"Immunoglobulins","url":"https://www.academia.edu/Documents/in/Immunoglobulins?f_ri=344106"},{"id":1426712,"name":"Immunoglobulin","url":"https://www.academia.edu/Documents/in/Immunoglobulin?f_ri=344106"},{"id":1716403,"name":"immunoglobulin G","url":"https://www.academia.edu/Documents/in/immunoglobulin_G?f_ri=344106"},{"id":2019324,"name":"Humoral Immunity","url":"https://www.academia.edu/Documents/in/Humoral_Immunity?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_21767278" data-work_id="21767278" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/21767278/Familial_influences_on_basal_salivary_cortisol_in_an_adult_population">Familial influences on basal salivary cortisol in an adult population</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">To understand the underlying genetic and environmental sources of individual variation in basal cortisol levels, we collected salivary cortisol at awakening and at six fixed time points during the day in adult twins and their singleton... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_21767278" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">To understand the underlying genetic and environmental sources of individual variation in basal cortisol levels, we collected salivary cortisol at awakening and at six fixed time points during the day in adult twins and their singleton siblings. Reported time of awakening was verified with heart rate and body movement recordings. Cortisol data were available for 199 MZ twins, 272 DZ twins and 229 singleton siblings from 309 twin families. No differences in cortisol means and variances were found between twins and singleton siblings. Additionally, the correlations for DZ twins and siblings were not significantly different, indicating generalizability of twin study results to the general population. Genetic model fitting showed heritability for cortisol levels during the awakening period (34% for cortisol level at awakening and 32% for cortisol level at 30 min after awakening) but not for cortisol levels later during the day. The current study shows that, while cortisol levels in the awakening period are influenced by genetic factors, cortisol levels throughout most of the day are not heritable, indicating that future gene finding studies for basal cortisol should focus on the first hour post-awakening. Q</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/21767278" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="5ea1709feff8866ffbfdee3d1ae7513d" rel="nofollow" data-download="{"attachment_id":42536926,"asset_id":21767278,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42536926/download_file?st=MTc0MDAzODkzNSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="36913687" href="https://tilburguniversity.academia.edu/NKupper">N. 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Reported time of awakening was verified with heart rate and body movement recordings. Cortisol data were available for 199 MZ twins, 272 DZ twins and 229 singleton siblings from 309 twin families. No differences in cortisol means and variances were found between twins and singleton siblings. Additionally, the correlations for DZ twins and siblings were not significantly different, indicating generalizability of twin study results to the general population. Genetic model fitting showed heritability for cortisol levels during the awakening period (34% for cortisol level at awakening and 32% for cortisol level at 30 min after awakening) but not for cortisol levels later during the day. The current study shows that, while cortisol levels in the awakening period are influenced by genetic factors, cortisol levels throughout most of the day are not heritable, indicating that future gene finding studies for basal cortisol should focus on the first hour post-awakening. Q","downloadable_attachments":[{"id":42536926,"asset_id":21767278,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":36913687,"first_name":"N.","last_name":"Kupper","domain_name":"tilburguniversity","page_name":"NKupper","display_name":"N. Kupper","profile_url":"https://tilburguniversity.academia.edu/NKupper?f_ri=344106","photo":"https://0.academia-photos.com/36913687/10529002/11750040/s65_n..kupper.jpg"}],"research_interests":[{"id":44151,"name":"Twins","url":"https://www.academia.edu/Documents/in/Twins?f_ri=344106","nofollow":true},{"id":58431,"name":"Cortisol","url":"https://www.academia.edu/Documents/in/Cortisol?f_ri=344106","nofollow":true},{"id":89121,"name":"Circadian Rhythm","url":"https://www.academia.edu/Documents/in/Circadian_Rhythm?f_ri=344106","nofollow":true},{"id":133761,"name":"Psychoneuroendocrinology","url":"https://www.academia.edu/Documents/in/Psychoneuroendocrinology?f_ri=344106","nofollow":true},{"id":148806,"name":"Siblings","url":"https://www.academia.edu/Documents/in/Siblings?f_ri=344106"},{"id":151950,"name":"Heritability","url":"https://www.academia.edu/Documents/in/Heritability?f_ri=344106"},{"id":188349,"name":"Pedigree","url":"https://www.academia.edu/Documents/in/Pedigree?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":976842,"name":"Salivary Cortisol","url":"https://www.academia.edu/Documents/in/Salivary_Cortisol?f_ri=344106"},{"id":1000427,"name":"Reference Values","url":"https://www.academia.edu/Documents/in/Reference_Values?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_24563380" data-work_id="24563380" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/24563380/Microbiologic_Effects_of_SnF2_and_NaF_Mouthrinses_in_Subjects_with_High_Caries_Activity_Results_after_One_Year">Microbiologic Effects of SnF2 and NaF Mouthrinses in Subjects with High Caries Activity: Results after One Year</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Twenty-two adults, considered to have high caries activity, rinsed for one yr with either SnF2 or acidulated NaF mouthrinses. Total colony-forming units and numbers of S. mutans and lactobacilli were estimated from saliva samples. Large... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_24563380" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Twenty-two adults, considered to have high caries activity, rinsed for one yr with either SnF2 or acidulated NaF mouthrinses. Total colony-forming units and numbers of S. mutans and lactobacilli were estimated from saliva samples. Large reductions were found in the number of recoverable S. mutans in subjects rinsing with SnF2 but not in the NaFgroup. J Dent Res 62(8):907-91 1</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/24563380" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="ac998828c5908bdc2b8ec7515a08b46f" rel="nofollow" data-download="{"attachment_id":44893815,"asset_id":24563380,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44893815/download_file?st=MTc0MDAzODkzNSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="47352716" href="https://independent.academia.edu/NormanTinanoff">Norman Tinanoff</a><script data-card-contents-for-user="47352716" type="text/json">{"id":47352716,"first_name":"Norman","last_name":"Tinanoff","domain_name":"independent","page_name":"NormanTinanoff","display_name":"Norman Tinanoff","profile_url":"https://independent.academia.edu/NormanTinanoff?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_24563380 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="24563380"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 24563380, container: ".js-paper-rank-work_24563380", }); 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Total colony-forming units and numbers of S. mutans and lactobacilli were estimated from saliva samples. Large reductions were found in the number of recoverable S. mutans in subjects rinsing with SnF2 but not in the NaFgroup. J Dent Res 62(8):907-91 1","downloadable_attachments":[{"id":44893815,"asset_id":24563380,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":47352716,"first_name":"Norman","last_name":"Tinanoff","domain_name":"independent","page_name":"NormanTinanoff","display_name":"Norman Tinanoff","profile_url":"https://independent.academia.edu/NormanTinanoff?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":596,"name":"Dentistry","url":"https://www.academia.edu/Documents/in/Dentistry?f_ri=344106","nofollow":true},{"id":106368,"name":"Lactobacillus","url":"https://www.academia.edu/Documents/in/Lactobacillus?f_ri=344106","nofollow":true},{"id":137728,"name":"Dental","url":"https://www.academia.edu/Documents/in/Dental?f_ri=344106","nofollow":true},{"id":146936,"name":"Fluorides","url":"https://www.academia.edu/Documents/in/Fluorides?f_ri=344106","nofollow":true},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=344106"},{"id":469032,"name":"Mouthwashes","url":"https://www.academia.edu/Documents/in/Mouthwashes?f_ri=344106"},{"id":868321,"name":"Streptococcus mutans","url":"https://www.academia.edu/Documents/in/Streptococcus_mutans?f_ri=344106"},{"id":1692309,"name":"Sodium Fluoride","url":"https://www.academia.edu/Documents/in/Sodium_Fluoride?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_34342225" data-work_id="34342225" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/34342225/Cognitive_Performance_and_Morning_Levels_of_Salivary_Cortisol_and%CE%B1_Amylase_in_Children_Reporting_High_vs_Low_Daily_Stress_Perception">Cognitive Performance and Morning Levels of Salivary Cortisol andα-Amylase in Children Reporting High vs. Low Daily Stress Perception</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Universidad Complutense de Madrid España ¿Cómo citar? 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Sixty high school students from the 9th grade were randomly assigned... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_30439268" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Little is known, about the influence of different exercise intensities on cognition, the concentration of steroid hormones (SHs), and their interaction in adolescents. Sixty high school students from the 9th grade were randomly assigned to two experimental (EG 1, EG 2) and a control group (CG). Saliva collection took place after a normal school lesson (t1) and after a 12min resting control or exercise (t2) in a defined heart rate (HR) interval (EG 1: 50-65% HR max, n = 18; EG 2: 70-85% HR max, n = 20; CG: no intervention, n = 21). Saliva was analyzed for Tand C. Cognitive performance was assessed using a working memory task (Letter Digit Span; LDS), which took place after t1 and t2. Repeated measure ANOVAs revealed a significant group by test interaction, indicating an increase of C and T level only for EG 2. Results for LDS showed a significant improvement due to exercise when groups were split into low and high performer at pre-test with a higher improvement of the low performers. In addition, post-test T levels negatively correlated with changes in LDS performance in EG 2. The results indicate that the concentrations of C and Tare intensity dependent, and that exercise improves working memory in low performing adolescents. Only increased T, however, seems to be related to pre-to-post-test changes in working memory by having a detrimental effect on performance. #</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/30439268" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a3228340dca997348d4406af6583804b" rel="nofollow" data-download="{"attachment_id":50881628,"asset_id":30439268,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/50881628/download_file?st=MTc0MDAzODkzNSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="35763086" href="https://independent.academia.edu/SergioMachado54">Sergio Machado</a><script data-card-contents-for-user="35763086" type="text/json">{"id":35763086,"first_name":"Sergio","last_name":"Machado","domain_name":"independent","page_name":"SergioMachado54","display_name":"Sergio Machado","profile_url":"https://independent.academia.edu/SergioMachado54?f_ri=344106","photo":"https://0.academia-photos.com/35763086/18173583/18158326/s65_sergio.machado.jpg"}</script></span></span></li><li class="js-paper-rank-work_30439268 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="30439268"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 30439268, container: ".js-paper-rank-work_30439268", }); 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Sixty high school students from the 9th grade were randomly assigned to two experimental (EG 1, EG 2) and a control group (CG). Saliva collection took place after a normal school lesson (t1) and after a 12min resting control or exercise (t2) in a defined heart rate (HR) interval (EG 1: 50-65% HR max, n = 18; EG 2: 70-85% HR max, n = 20; CG: no intervention, n = 21). Saliva was analyzed for Tand C. Cognitive performance was assessed using a working memory task (Letter Digit Span; LDS), which took place after t1 and t2. Repeated measure ANOVAs revealed a significant group by test interaction, indicating an increase of C and T level only for EG 2. Results for LDS showed a significant improvement due to exercise when groups were split into low and high performer at pre-test with a higher improvement of the low performers. In addition, post-test T levels negatively correlated with changes in LDS performance in EG 2. The results indicate that the concentrations of C and Tare intensity dependent, and that exercise improves working memory in low performing adolescents. Only increased T, however, seems to be related to pre-to-post-test changes in working memory by having a detrimental effect on performance. #","downloadable_attachments":[{"id":50881628,"asset_id":30439268,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":35763086,"first_name":"Sergio","last_name":"Machado","domain_name":"independent","page_name":"SergioMachado54","display_name":"Sergio Machado","profile_url":"https://independent.academia.edu/SergioMachado54?f_ri=344106","photo":"https://0.academia-photos.com/35763086/18173583/18158326/s65_sergio.machado.jpg"}],"research_interests":[{"id":4212,"name":"Cognition","url":"https://www.academia.edu/Documents/in/Cognition?f_ri=344106","nofollow":true},{"id":8538,"name":"Working 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Exercise","url":"https://www.academia.edu/Documents/in/Physical_Exercise?f_ri=344106"},{"id":1144102,"name":"Task Performance and Analysis","url":"https://www.academia.edu/Documents/in/Task_Performance_and_Analysis?f_ri=344106"},{"id":1146831,"name":"Exercise Test","url":"https://www.academia.edu/Documents/in/Exercise_Test?f_ri=344106"},{"id":2183225,"name":"Physical Endurance","url":"https://www.academia.edu/Documents/in/Physical_Endurance?f_ri=344106"},{"id":2444775,"name":"Psychomotor Performance","url":"https://www.academia.edu/Documents/in/Psychomotor_Performance?f_ri=344106"},{"id":2467548,"name":"Neuropsychological Tests","url":"https://www.academia.edu/Documents/in/Neuropsychological_Tests?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_30076686 coauthored" data-work_id="30076686" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/30076686/Prevalence_of_feline_immunodeficiency_virus_and_other_retroviral_infections_in_sick_cats_in_Italy">Prevalence of feline immunodeficiency virus and other retroviral infections in sick cats in Italy</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/30076686" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="ef427f8669414962dfed133de1204c70" rel="nofollow" data-download="{"attachment_id":50525888,"asset_id":30076686,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/50525888/download_file?st=MTc0MDAzODkzNSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32839875" href="https://independent.academia.edu/FulviaBaldinotti">Fulvia Baldinotti</a><script data-card-contents-for-user="32839875" type="text/json">{"id":32839875,"first_name":"Fulvia","last_name":"Baldinotti","domain_name":"independent","page_name":"FulviaBaldinotti","display_name":"Fulvia Baldinotti","profile_url":"https://independent.academia.edu/FulviaBaldinotti?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-30076686">+1</span><div class="hidden js-additional-users-30076686"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/PatriziaBandecchi">Patrizia Bandecchi</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-30076686'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-30076686').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_30076686 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="30076686"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 30076686, container: ".js-paper-rank-work_30076686", }); });</script></li><li class="js-percentile-work_30076686 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 30076686; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_30076686"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_30076686 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="30076686"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 30076686; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=30076686]").text(description); $(".js-view-count-work_30076686").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_30076686").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="30076686"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="173" rel="nofollow" href="https://www.academia.edu/Documents/in/Zoology">Zoology</a>, <script data-card-contents-for-ri="173" type="text/json">{"id":173,"name":"Zoology","url":"https://www.academia.edu/Documents/in/Zoology?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="41088" rel="nofollow" href="https://www.academia.edu/Documents/in/Cats">Cats</a>, <script data-card-contents-for-ri="41088" type="text/json">{"id":41088,"name":"Cats","url":"https://www.academia.edu/Documents/in/Cats?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="45213" rel="nofollow" href="https://www.academia.edu/Documents/in/Italy">Italy</a>, <script data-card-contents-for-ri="45213" type="text/json">{"id":45213,"name":"Italy","url":"https://www.academia.edu/Documents/in/Italy?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="289330" rel="nofollow" href="https://www.academia.edu/Documents/in/Prevalence">Prevalence</a><script data-card-contents-for-ri="289330" type="text/json">{"id":289330,"name":"Prevalence","url":"https://www.academia.edu/Documents/in/Prevalence?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=30076686]'), work: {"id":30076686,"title":"Prevalence of feline immunodeficiency virus and other retroviral infections in sick cats in Italy","created_at":"2016-11-24T12:11:51.332-08:00","url":"https://www.academia.edu/30076686/Prevalence_of_feline_immunodeficiency_virus_and_other_retroviral_infections_in_sick_cats_in_Italy?f_ri=344106","dom_id":"work_30076686","summary":null,"downloadable_attachments":[{"id":50525888,"asset_id":30076686,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32839875,"first_name":"Fulvia","last_name":"Baldinotti","domain_name":"independent","page_name":"FulviaBaldinotti","display_name":"Fulvia Baldinotti","profile_url":"https://independent.academia.edu/FulviaBaldinotti?f_ri=344106","photo":"/images/s65_no_pic.png"},{"id":32956083,"first_name":"Patrizia","last_name":"Bandecchi","domain_name":"independent","page_name":"PatriziaBandecchi","display_name":"Patrizia Bandecchi","profile_url":"https://independent.academia.edu/PatriziaBandecchi?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":173,"name":"Zoology","url":"https://www.academia.edu/Documents/in/Zoology?f_ri=344106","nofollow":true},{"id":41088,"name":"Cats","url":"https://www.academia.edu/Documents/in/Cats?f_ri=344106","nofollow":true},{"id":45213,"name":"Italy","url":"https://www.academia.edu/Documents/in/Italy?f_ri=344106","nofollow":true},{"id":289330,"name":"Prevalence","url":"https://www.academia.edu/Documents/in/Prevalence?f_ri=344106","nofollow":true},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":644860,"name":"Veterinary Sciences","url":"https://www.academia.edu/Documents/in/Veterinary_Sciences?f_ri=344106"},{"id":782120,"name":"Veterinary Immunology","url":"https://www.academia.edu/Documents/in/Veterinary_Immunology?f_ri=344106"},{"id":1272906,"name":"Enzyme Linked Immunosorbent Assay","url":"https://www.academia.edu/Documents/in/Enzyme_Linked_Immunosorbent_Assay?f_ri=344106"},{"id":1566436,"name":"Feline immunodeficiency virus","url":"https://www.academia.edu/Documents/in/Feline_immunodeficiency_virus?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_9187459" data-work_id="9187459" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/9187459/Smoking_During_Pregnancy_and_Newborn_Neurobehavior">Smoking During Pregnancy and Newborn Neurobehavior</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">Objective. This was a prospective study of the effects of maternal smoking during pregnancy on newborn neurobehavior, including dose-response relationships using self-report and a bioassay of nicotine exposure.</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/9187459" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="1e165ff6e91b56130d5311a4efddc442" rel="nofollow" data-download="{"attachment_id":47858027,"asset_id":9187459,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/47858027/download_file?st=MTc0MDAzODkzNSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="21013016" href="https://georgetown.academia.edu/RaymondNiaura">Raymond Niaura</a><script data-card-contents-for-user="21013016" type="text/json">{"id":21013016,"first_name":"Raymond","last_name":"Niaura","domain_name":"georgetown","page_name":"RaymondNiaura","display_name":"Raymond Niaura","profile_url":"https://georgetown.academia.edu/RaymondNiaura?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_9187459 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="9187459"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 9187459, container: ".js-paper-rank-work_9187459", }); });</script></li><li class="js-percentile-work_9187459 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 9187459; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_9187459"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_9187459 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="9187459"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 9187459; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=9187459]").text(description); $(".js-view-count-work_9187459").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_9187459").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="9187459"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">24</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="631" rel="nofollow" href="https://www.academia.edu/Documents/in/Pediatrics">Pediatrics</a>, <script data-card-contents-for-ri="631" type="text/json">{"id":631,"name":"Pediatrics","url":"https://www.academia.edu/Documents/in/Pediatrics?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4583" rel="nofollow" href="https://www.academia.edu/Documents/in/Child_Development">Child Development</a>, <script data-card-contents-for-ri="4583" type="text/json">{"id":4583,"name":"Child Development","url":"https://www.academia.edu/Documents/in/Child_Development?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=344106","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26879" rel="nofollow" href="https://www.academia.edu/Documents/in/Social_Class">Social Class</a><script data-card-contents-for-ri="26879" type="text/json">{"id":26879,"name":"Social Class","url":"https://www.academia.edu/Documents/in/Social_Class?f_ri=344106","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=9187459]'), work: {"id":9187459,"title":"Smoking During Pregnancy and Newborn Neurobehavior","created_at":"2014-11-07T23:47:27.960-08:00","url":"https://www.academia.edu/9187459/Smoking_During_Pregnancy_and_Newborn_Neurobehavior?f_ri=344106","dom_id":"work_9187459","summary":"Objective. This was a prospective study of the effects of maternal smoking during pregnancy on newborn neurobehavior, including dose-response relationships using self-report and a bioassay of nicotine exposure.","downloadable_attachments":[{"id":47858027,"asset_id":9187459,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":21013016,"first_name":"Raymond","last_name":"Niaura","domain_name":"georgetown","page_name":"RaymondNiaura","display_name":"Raymond Niaura","profile_url":"https://georgetown.academia.edu/RaymondNiaura?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":631,"name":"Pediatrics","url":"https://www.academia.edu/Documents/in/Pediatrics?f_ri=344106","nofollow":true},{"id":4583,"name":"Child Development","url":"https://www.academia.edu/Documents/in/Child_Development?f_ri=344106","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=344106","nofollow":true},{"id":26879,"name":"Social Class","url":"https://www.academia.edu/Documents/in/Social_Class?f_ri=344106","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=344106"},{"id":62550,"name":"Pregnancy","url":"https://www.academia.edu/Documents/in/Pregnancy?f_ri=344106"},{"id":75318,"name":"Smoking","url":"https://www.academia.edu/Documents/in/Smoking?f_ri=344106"},{"id":91360,"name":"Nicotine","url":"https://www.academia.edu/Documents/in/Nicotine?f_ri=344106"},{"id":110254,"name":"Alcohol Drinking","url":"https://www.academia.edu/Documents/in/Alcohol_Drinking?f_ri=344106"},{"id":127182,"name":"Self Disclosure","url":"https://www.academia.edu/Documents/in/Self_Disclosure?f_ri=344106"},{"id":147195,"name":"Central Nervous System","url":"https://www.academia.edu/Documents/in/Central_Nervous_System?f_ri=344106"},{"id":162282,"name":"Mothers","url":"https://www.academia.edu/Documents/in/Mothers?f_ri=344106"},{"id":253560,"name":"Newborn Infant","url":"https://www.academia.edu/Documents/in/Newborn_Infant?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":375053,"name":"Dose Response Relationship","url":"https://www.academia.edu/Documents/in/Dose_Response_Relationship?f_ri=344106"},{"id":404129,"name":"Maternal Smoking","url":"https://www.academia.edu/Documents/in/Maternal_Smoking?f_ri=344106"},{"id":987472,"name":"Gestation","url":"https://www.academia.edu/Documents/in/Gestation?f_ri=344106"},{"id":1281259,"name":"Neonatal abstinence syndrome","url":"https://www.academia.edu/Documents/in/Neonatal_abstinence_syndrome?f_ri=344106"},{"id":1312754,"name":"Prospective Study","url":"https://www.academia.edu/Documents/in/Prospective_Study?f_ri=344106"},{"id":1537664,"name":"Psychomotor Development","url":"https://www.academia.edu/Documents/in/Psychomotor_Development?f_ri=344106"},{"id":1559335,"name":"Cotinine","url":"https://www.academia.edu/Documents/in/Cotinine?f_ri=344106"},{"id":1653420,"name":"Maternal-fetal exchange","url":"https://www.academia.edu/Documents/in/Maternal-fetal_exchange?f_ri=344106"},{"id":1878977,"name":"Maternal Exposure","url":"https://www.academia.edu/Documents/in/Maternal_Exposure?f_ri=344106"},{"id":2051024,"name":"Infant Behavior","url":"https://www.academia.edu/Documents/in/Infant_Behavior?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_26692734" data-work_id="26692734" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/26692734/Social_cognition_under_stress_Differential_effects_of_stress_induced_cortisol_elevations_in_healthy_young_men_and_women">Social cognition under stress: Differential effects of stress-induced cortisol elevations in healthy young men and women</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Humans as social beings often have to perform complex social cognitive tasks while under stress (e.g., during a social conflict). Previous research has established that the brain regions responsible for social cognitive tasks are target... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_26692734" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Humans as social beings often have to perform complex social cognitive tasks while under stress (e.g., during a social conflict). Previous research has established that the brain regions responsible for social cognitive tasks are target regions for stress hormones. However, little experimental research has been done testing the acute effects of stress on social cognition. Here, we investigated whether stress exposure and the ensuing glucocorticoid (i.e., cortisol) elevations affect social cognition. Thirty-two men and 32 women were exposed to either a psychosocial stress or a non-stressful control test before assessing their social cognition using the Reading the Mind in the Eyes Test (RMET) and the Movie for the Assessment of Social Cognition (MASC). Results showed differential effects of stress-induced cortisol responses among men and women for the MASC, but not the RMET. Among men, high cortisol responders displayed elevated MASC scores compared with low cortisol responders. Moreover, for stressed men a positive association between the magnitude of the cortisol responses to the stressor and MASC scores emerged. Among women, enhanced MASC scores were found for low cortisol responders relative to high cortisol responders and non-stressed controls. A strong negative association between cortisol reactivity and MASC scores was found among women. These results imply sex specific effects of glucocorticoids on social cognition and partially support the idea of sex differences in biobehavioral stress responses, with men engaging in fight-or-flight responses while women may react to stress with tending and befriending behavior.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/26692734" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="5844a50f6593576bd223880a9fd70701" rel="nofollow" data-download="{"attachment_id":46974864,"asset_id":26692734,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46974864/download_file?st=MTc0MDAzODkzNSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="50686548" href="https://hu-berlin.academia.edu/IsabelDziobek">Isabel Dziobek</a><script data-card-contents-for-user="50686548" type="text/json">{"id":50686548,"first_name":"Isabel","last_name":"Dziobek","domain_name":"hu-berlin","page_name":"IsabelDziobek","display_name":"Isabel Dziobek","profile_url":"https://hu-berlin.academia.edu/IsabelDziobek?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_26692734 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="26692734"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 26692734, container: ".js-paper-rank-work_26692734", }); 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Previous research has established that the brain regions responsible for social cognitive tasks are target regions for stress hormones. However, little experimental research has been done testing the acute effects of stress on social cognition. Here, we investigated whether stress exposure and the ensuing glucocorticoid (i.e., cortisol) elevations affect social cognition. Thirty-two men and 32 women were exposed to either a psychosocial stress or a non-stressful control test before assessing their social cognition using the Reading the Mind in the Eyes Test (RMET) and the Movie for the Assessment of Social Cognition (MASC). Results showed differential effects of stress-induced cortisol responses among men and women for the MASC, but not the RMET. Among men, high cortisol responders displayed elevated MASC scores compared with low cortisol responders. Moreover, for stressed men a positive association between the magnitude of the cortisol responses to the stressor and MASC scores emerged. Among women, enhanced MASC scores were found for low cortisol responders relative to high cortisol responders and non-stressed controls. A strong negative association between cortisol reactivity and MASC scores was found among women. These results imply sex specific effects of glucocorticoids on social cognition and partially support the idea of sex differences in biobehavioral stress responses, with men engaging in fight-or-flight responses while women may react to stress with tending and befriending behavior.","downloadable_attachments":[{"id":46974864,"asset_id":26692734,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":50686548,"first_name":"Isabel","last_name":"Dziobek","domain_name":"hu-berlin","page_name":"IsabelDziobek","display_name":"Isabel Dziobek","profile_url":"https://hu-berlin.academia.edu/IsabelDziobek?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":4212,"name":"Cognition","url":"https://www.academia.edu/Documents/in/Cognition?f_ri=344106","nofollow":true},{"id":4626,"name":"Social Cognition","url":"https://www.academia.edu/Documents/in/Social_Cognition?f_ri=344106","nofollow":true},{"id":9729,"name":"Stress","url":"https://www.academia.edu/Documents/in/Stress?f_ri=344106","nofollow":true},{"id":18440,"name":"Social Perception","url":"https://www.academia.edu/Documents/in/Social_Perception?f_ri=344106","nofollow":true},{"id":30561,"name":"Experimental Research","url":"https://www.academia.edu/Documents/in/Experimental_Research?f_ri=344106"},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=344106"},{"id":58431,"name":"Cortisol","url":"https://www.academia.edu/Documents/in/Cortisol?f_ri=344106"},{"id":75509,"name":"Sex Difference","url":"https://www.academia.edu/Documents/in/Sex_Difference?f_ri=344106"},{"id":98707,"name":"Stress response","url":"https://www.academia.edu/Documents/in/Stress_response?f_ri=344106"},{"id":143965,"name":"Social Conflict","url":"https://www.academia.edu/Documents/in/Social_Conflict?f_ri=344106"},{"id":314162,"name":"Psychological Tests","url":"https://www.academia.edu/Documents/in/Psychological_Tests?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":564882,"name":"Trier Social Stress Test","url":"https://www.academia.edu/Documents/in/Trier_Social_Stress_Test?f_ri=344106"},{"id":816819,"name":"Psychological Models","url":"https://www.academia.edu/Documents/in/Psychological_Models?f_ri=344106"},{"id":851271,"name":"Psychosocial Stress","url":"https://www.academia.edu/Documents/in/Psychosocial_Stress?f_ri=344106"},{"id":993183,"name":"Young Men","url":"https://www.academia.edu/Documents/in/Young_Men?f_ri=344106"},{"id":1293308,"name":"Glucocorticoids","url":"https://www.academia.edu/Documents/in/Glucocorticoids?f_ri=344106"},{"id":1540546,"name":"Video Recording","url":"https://www.academia.edu/Documents/in/Video_Recording?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_13567059 coauthored" data-work_id="13567059" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13567059/Detection_of_salivary_antibodies_to_crude_antigens_of_Opisthorchis_viverrini_in_opisthorchiasis_and_cholangiocarcinoma_patients">Detection of salivary antibodies to crude antigens of Opisthorchis viverrini in opisthorchiasis and cholangiocarcinoma patients</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">Opisthorchis viverrini (O. viverrini; known as human liver fluke) is a major health problem in the northeastern region of Thailand. Infection with O.</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13567059" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="0a12cf284d8e13c0d3da0f246c68032d" rel="nofollow" data-download="{"attachment_id":45208294,"asset_id":13567059,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45208294/download_file?st=MTc0MDAzODkzNSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32749728" href="https://mahidol.academia.edu/ChanitraThuwajit">Chanitra Thuwajit</a><script data-card-contents-for-user="32749728" type="text/json">{"id":32749728,"first_name":"Chanitra","last_name":"Thuwajit","domain_name":"mahidol","page_name":"ChanitraThuwajit","display_name":"Chanitra Thuwajit","profile_url":"https://mahidol.academia.edu/ChanitraThuwajit?f_ri=344106","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-13567059">+1</span><div class="hidden js-additional-users-13567059"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/PaiboonSithithaworn">Paiboon Sithithaworn</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-13567059'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-13567059').html(); 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known as human liver fluke) is a major health problem in the northeastern region of Thailand. Infection with O.","downloadable_attachments":[{"id":45208294,"asset_id":13567059,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32749728,"first_name":"Chanitra","last_name":"Thuwajit","domain_name":"mahidol","page_name":"ChanitraThuwajit","display_name":"Chanitra Thuwajit","profile_url":"https://mahidol.academia.edu/ChanitraThuwajit?f_ri=344106","photo":"/images/s65_no_pic.png"},{"id":32089993,"first_name":"Paiboon","last_name":"Sithithaworn","domain_name":"independent","page_name":"PaiboonSithithaworn","display_name":"Paiboon Sithithaworn","profile_url":"https://independent.academia.edu/PaiboonSithithaworn?f_ri=344106","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":596,"name":"Dentistry","url":"https://www.academia.edu/Documents/in/Dentistry?f_ri=344106","nofollow":true},{"id":2702,"name":"Immune response","url":"https://www.academia.edu/Documents/in/Immune_response?f_ri=344106","nofollow":true},{"id":10096,"name":"Thailand","url":"https://www.academia.edu/Documents/in/Thailand?f_ri=344106","nofollow":true},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=344106","nofollow":true},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=344106"},{"id":344106,"name":"Saliva","url":"https://www.academia.edu/Documents/in/Saliva?f_ri=344106"},{"id":387476,"name":"Health Problems","url":"https://www.academia.edu/Documents/in/Health_Problems?f_ri=344106"},{"id":403821,"name":"Cholangiocarcinoma","url":"https://www.academia.edu/Documents/in/Cholangiocarcinoma?f_ri=344106"},{"id":901876,"name":"Sensitivity and Specificity","url":"https://www.academia.edu/Documents/in/Sensitivity_and_Specificity?f_ri=344106"},{"id":1716403,"name":"immunoglobulin G","url":"https://www.academia.edu/Documents/in/immunoglobulin_G?f_ri=344106"}]}, }) } })();</script></ul></li></ul></div></div></div><div class="u-taCenter Pagination"><ul class="pagination"><li class="next_page"><a href="/Documents/in/Saliva?after=50%2C24477747" rel="next">Next</a></li><li class="last next"><a href="/Documents/in/Saliva?page=last">Last »</a></li></ul></div></div><div class="hidden-xs hidden-sm"><div class="u-pl6x"><div style="width: 300px;"><div class="panel panel-flat u-mt7x"><div class="panel-heading u-p5x"><div class="u-tcGrayDark u-taCenter u-fw700 u-textUppercase">Related Topics</div></div><ul class="list-group"><li class="list-group-item media_v2 u-mt0x u-p3x"><div class="media-body"><div class="u-tcGrayDarker u-fw700"><a class="u-tcGrayDarker" rel="nofollow" href="https://www.academia.edu/Documents/in/Oral_health">Oral health</a></div></div><div class="media-right media-middle"><a class="u-tcGreen u-textDecorationNone u-linkUnstyled u-fw500 hidden" 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