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Search results for: Muhd Fadhil Nuruddin

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</div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Muhd Fadhil Nuruddin</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">13</span> Performance of Fiber Reinforced Self-Compacting Concrete Containing Different Pozzolanic Materials</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20Fathi%20Mohamed">Ahmed Fathi Mohamed</a>, <a href="https://publications.waset.org/abstracts/search?q=Nasir%20Shafiq"> Nasir Shafiq</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhd%20Fadhil%20Nuruddin"> Muhd Fadhil Nuruddin</a>, <a href="https://publications.waset.org/abstracts/search?q=Ali%20Elheber%20Ahmed"> Ali Elheber Ahmed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Steel fiber adds to Self-Compacting Concrete (SCC) to enhance it is properties and achieves the requirement. This research work focus on the using of different percentage of steel fiber in SCC mixture contains fly ash and microwave incinerator rice husk ash (MIRHA) as supplementary material. Fibers affect several characteristics of SCC in the fresh and the hardened state. To optimize fiber-reinforced self-compacting concrete (FSCC), The possible fiber content of a given mix composition is an essential input parameter. The aim of the research is to study the properties of fiber reinforced self鈥揷ompacting (FRSCC) and to develop the expert system/computer program of mix proportion for calculating the steel fiber content and pozzolanic replacement that can be applied to investigate the compressive strength of FSCC mix. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=self-compacting%20concrete" title="self-compacting concrete">self-compacting concrete</a>, <a href="https://publications.waset.org/abstracts/search?q=silica%20fume" title=" silica fume"> silica fume</a>, <a href="https://publications.waset.org/abstracts/search?q=steel%20fiber" title=" steel fiber"> steel fiber</a>, <a href="https://publications.waset.org/abstracts/search?q=fresh%20taste" title=" fresh taste"> fresh taste</a> </p> <a href="https://publications.waset.org/abstracts/1321/performance-of-fiber-reinforced-self-compacting-concrete-containing-different-pozzolanic-materials" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/1321.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">574</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">12</span> Ground Track Assessment Using Electrical Resistivity Tomography Application</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Noryani%20Natasha%20Yahaya">Noryani Natasha Yahaya</a>, <a href="https://publications.waset.org/abstracts/search?q=Anas%20Ibrahim"> Anas Ibrahim</a>, <a href="https://publications.waset.org/abstracts/search?q=Juraidah%20Ahmad"> Juraidah Ahmad</a>, <a href="https://publications.waset.org/abstracts/search?q=Azura%20Ahmad"> Azura Ahmad</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohd%20Ikmal%20Fazlan%20Rosli"> Mohd Ikmal Fazlan Rosli</a>, <a href="https://publications.waset.org/abstracts/search?q=Zailan%20Ramli"> Zailan Ramli</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhd%20Sidek%20Muhd%20Norhasri"> Muhd Sidek Muhd Norhasri</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The subgrade formation is an important element of the railway structure which holds overall track stability. Conventional track maintenance involves many substructure component replacements, as well as track re-ballasting on a regular basis is partially contributed to the embankment's long-term settlement problem. For subgrade long-term stability analysis, the geophysical method is commonly being used to diagnose those hidden sources/mechanisms of track deterioration problems that the normal visual method is unable to detect. Electrical resistivity tomography (ERT) is one of the applicable geophysical tools that are helpful in railway subgrade inspection/track monitoring due to its flexibility and reliability of the analysis. The ERT was conducted at KM 23.0 of Pinang Tunggal track to investigate the subgrade of railway track through the characterization/mapping on track formation profiling which was directly generated using 2D analysis of Res2dinv software. The profiles will allow examination of the presence and spatial extent of a significant subgrade layer and screening of any poor contact of soil boundary. Based on the finding, there is a mix/interpretation/intermixing of an interlayer between the sub-ballast and the sand. Although the embankment track considered here is at no immediate risk of settlement effect or any failure, the regular monitoring of track鈥檚 location will allow early correction maintenance if necessary. The developed data of track formation clearly shows the similarity of the side view with the assessed track. The data visualization in the 2D section of the track embankment agreed well with the initial assumption based on the main element structure general side view. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ground%20track" title="ground track">ground track</a>, <a href="https://publications.waset.org/abstracts/search?q=assessment" title=" assessment"> assessment</a>, <a href="https://publications.waset.org/abstracts/search?q=resistivity" title=" resistivity"> resistivity</a>, <a href="https://publications.waset.org/abstracts/search?q=geophysical%20railway" title=" geophysical railway"> geophysical railway</a>, <a href="https://publications.waset.org/abstracts/search?q=method" title=" method"> method</a> </p> <a href="https://publications.waset.org/abstracts/147484/ground-track-assessment-using-electrical-resistivity-tomography-application" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/147484.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">155</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">11</span> Ground States of Structure of Even 鹿鈦扳伌-鹿鈦扳伓 Ru Isotopes</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=I.%20Hossain">I. Hossain</a>, <a href="https://publications.waset.org/abstracts/search?q=Huda%20H.%20Kassim"> Huda H. Kassim</a>, <a href="https://publications.waset.org/abstracts/search?q=Fadhil%20I.%20Sharrad"> Fadhil I. Sharrad</a>, <a href="https://publications.waset.org/abstracts/search?q=Said%20A.%20Mansour"> Said A. Mansour</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this conference, we apply the interacting boson model-1 (IBM-1) formula for U(5) symmetry in order to calculate the energy levels and reduced transition probabilities for a few yrast transitions in Ru with neutron N=60, 62. The neutron rich even-even isotopes of Ru are very interesting to investigate using IBM-1, because even 104,106Ru isotopes are great consequence due to excited near the magic number 50. The calculation of ground state band and B(E2) values using IBM-1 for Z=44 are not calculated to describe the valuable information of nuclear structure by U(5) limit. The parameters in the formula are deduced based on the experimental energy level and value of B(E2, 2+->0+). The yrast states and transition strength B(E2) from 1st 4+ to 1st 2+, 1st 6+ to 1st 4+ and 1st 8+ to 1st 6+ states of Ru for even N= 60, 62 were calculated. The quadrupole moments, deformation parameters and U(5) limit were discussed for those nuclei. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=B%28E2%29" title="B(E2)">B(E2)</a>, <a href="https://publications.waset.org/abstracts/search?q=energy%20level" title=" energy level"> energy level</a>, <a href="https://publications.waset.org/abstracts/search?q=%C2%B9%E2%81%B0%E2%81%B4Ru" title=" 鹿鈦扳伌Ru"> 鹿鈦扳伌Ru</a>, <a href="https://publications.waset.org/abstracts/search?q=%C2%B9%E2%81%B0%E2%81%B6Ru" title=" 鹿鈦扳伓Ru"> 鹿鈦扳伓Ru</a> </p> <a href="https://publications.waset.org/abstracts/56470/ground-states-of-structure-of-even-14-16-ru-isotopes" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/56470.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">348</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10</span> A Study on the Response of Vacuum Consolidation on Soft Clay in Combination with Prefabricated Vertical Drain (PVD), Embankment and Surcharge Preloading</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sharmeelee%20Subramaniam">Sharmeelee Subramaniam</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhd%20Harris%20Ramli"> Muhd Harris Ramli</a>, <a href="https://publications.waset.org/abstracts/search?q=Fauziah%20Ahmad"> Fauziah Ahmad</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The application of vacuum pressure to accelerate ground consolidation has been growing significantly in recent years. This ground improvement technique has its advantages, especially in areas where suitable fill is scarce, as it minimizes the surcharge fill height required for the preloading. A study was carried out to examine the response of soft subsoil subjected to vacuum consolidation in combination with embankment loading, surcharge preloading and PVD with two-way drainage. This paper shall describe a procedure to determine the optimum surcharge height and penetration depth of prefabricated vertical drains (PVD) where vacuum consolidation is combined with the use of PVD in soft clay deposits with two-way drainage. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=prefabricated%20vertical%20drain" title="prefabricated vertical drain">prefabricated vertical drain</a>, <a href="https://publications.waset.org/abstracts/search?q=soft%20soil" title=" soft soil"> soft soil</a>, <a href="https://publications.waset.org/abstracts/search?q=surcharge%20preload" title=" surcharge preload"> surcharge preload</a>, <a href="https://publications.waset.org/abstracts/search?q=vacuum%20consolidation" title=" vacuum consolidation"> vacuum consolidation</a> </p> <a href="https://publications.waset.org/abstracts/163568/a-study-on-the-response-of-vacuum-consolidation-on-soft-clay-in-combination-with-prefabricated-vertical-drain-pvd-embankment-and-surcharge-preloading" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/163568.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">83</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9</span> The Design of Broadband 8x2 Phased Array 5G Antenna MIMO 28 GHz for Base Station</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20Saiful%20Fadhil%20Reyhan">Muhammad Saiful Fadhil Reyhan</a>, <a href="https://publications.waset.org/abstracts/search?q=Yusnita%20Rahayu"> Yusnita Rahayu</a>, <a href="https://publications.waset.org/abstracts/search?q=Fadhel%20Muhammadsyah"> Fadhel Muhammadsyah</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper proposed a design of 16 elements, 8x2 linear fed patch antenna array with 16 ports, for 28 GHz, mm-wave band 5G for base station. The phased array covers along the azimuth plane to provide the coverage to the users in omnidirectional. The proposed antenna is designed RT Duroid 5880 substrate with the overall size of 85x35.6x0.787 mm<sup>3</sup>. The array is operating from 27.43 GHz to 28.34 GHz with a 910 MHz impedance bandwidth. The gain of the array is 18.3 dB, while the suppression of the side lobes is -1.0 dB. The main lobe direction of the array is 15 deg. The array shows a high array gain throughout the impedance bandwidth with overall of VSWR is below 1.12. The design will be proposed in single element and 16 elements antenna. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=5G%20antenna" title="5G antenna">5G antenna</a>, <a href="https://publications.waset.org/abstracts/search?q=28%20GHz" title=" 28 GHz"> 28 GHz</a>, <a href="https://publications.waset.org/abstracts/search?q=MIMO" title=" MIMO"> MIMO</a>, <a href="https://publications.waset.org/abstracts/search?q=omnidirectional" title=" omnidirectional"> omnidirectional</a>, <a href="https://publications.waset.org/abstracts/search?q=phased%20array" title=" phased array"> phased array</a>, <a href="https://publications.waset.org/abstracts/search?q=base%20station" title=" base station"> base station</a>, <a href="https://publications.waset.org/abstracts/search?q=broadband" title=" broadband"> broadband</a> </p> <a href="https://publications.waset.org/abstracts/85986/the-design-of-broadband-8x2-phased-array-5g-antenna-mimo-28-ghz-for-base-station" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/85986.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">249</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">8</span> Controlling the Surface Morphology of the Biocompatible Hydroxyapatite Layer Deposited by Using a Flame-Coating</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nabaa%20M.%20Abdul%20Rahim">Nabaa M. Abdul Rahim</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammed%20A.Kadhim"> Mohammed A.Kadhim</a>, <a href="https://publications.waset.org/abstracts/search?q=Fadhil%20K.%20Fuliful"> Fadhil K. Fuliful</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A biocompatible layer is prepared from calcium phosphate, which plays a role in building damaged bones and is used in many applications. In this research, calcium phosphate is coated on stainless steel substrates (SS 316) by using the flame coating. FE-SEM images show that the behavior of the sample surfaces varies with distance, at 3cm, appeared with nanostructures of bumps shaped of diameter about 317 nm. The contents of the elements are analyzed by energy-dispersive X-ray spectroscopy (EDX). The chemical elements C, Ca, Fe, Ni, Cr, Mn and O corresponding to calcium phosphate and the alloy are revealed by EDX analysis of the coating layer. XRD patterns for the calcium phosphate layers indicate the formation of the Hap layer on the deposited layers. The samples are immersed in a solution of simulated body fluids (SBF) for 21 days to examine the biocompatibility, as the tests show that the calcium phosphate ratio of 1.65 is the appropriate and biocompatible ratio in the human body. The assays show antibacterial activity using the diffusion disk procedure. On the surface of the agar, observed infested E.coli bacteria and incubated for 24 hours at 37掳C. Bacteria grow on the entire agar rather than in some areas around some samples at a distance of 3 cm from the flame hole. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biomaterial" title="biomaterial">biomaterial</a>, <a href="https://publications.waset.org/abstracts/search?q=flame%20coating" title=" flame coating"> flame coating</a>, <a href="https://publications.waset.org/abstracts/search?q=antibacterial%20activity" title=" antibacterial activity"> antibacterial activity</a>, <a href="https://publications.waset.org/abstracts/search?q=stainless%20steel" title=" stainless steel"> stainless steel</a> </p> <a href="https://publications.waset.org/abstracts/161818/controlling-the-surface-morphology-of-the-biocompatible-hydroxyapatite-layer-deposited-by-using-a-flame-coating" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/161818.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">97</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">7</span> New Quinazoline Derivative Exhibit Cytotoxic Effect agaisnt MCF-7 Human Breast Cancer Cell</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Maryam%20Zahedifard">Maryam Zahedifard</a>, <a href="https://publications.waset.org/abstracts/search?q=Fadhil%20Lafta%20Faraj"> Fadhil Lafta Faraj</a>, <a href="https://publications.waset.org/abstracts/search?q=Nazia%20Abdul%20Majid"> Nazia Abdul Majid</a>, <a href="https://publications.waset.org/abstracts/search?q=Hapipah%20Mohd%20Ali"> Hapipah Mohd Ali</a>, <a href="https://publications.waset.org/abstracts/search?q=Mahmood%20Ameen%20Abdulla"> Mahmood Ameen Abdulla</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The new quinazoline Schiff bases have been synthesized through condensation reaction of 2-aminobenzhydrazide with 5-bromosalicylaldehyde and 3-methoxy-5-bromosalicylaldehyde. The compound was investigated for anticancer activity against MCF-7 human breast cancer cell line. It demonstrated a remarkable antiproliferative effect, with an IC50 value of 3.41卤0.34, after 72 hours of treatment. Most apoptosis morphological features in treated MCF-7 cells were observed by AO/PI staining. The results of cell cycle analysis indicate that compounds did not induce S and M phase arrest in cell after 24 hours of treatment. Furthermore, MCF-7 cells treated with compound subjected to apoptosis death, as exhibited by perturbation of mitochondrial membrane potential and cytochrome C release as well as increase in ROS generation. We also found activation of caspases 3/7 and -9. Moreover, acute toxicity results demonstrated the nontoxic nature of the compounds in mice. Our results showed the selected compound significantly induce apoptosis in MCF-7 cells via intrinsic pathway, which might be considered as a potential candidate for further in vivo and clinical breast cancer studies. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=quinazoline%20Schiff%20base" title="quinazoline Schiff base">quinazoline Schiff base</a>, <a href="https://publications.waset.org/abstracts/search?q=apoptosis" title=" apoptosis"> apoptosis</a>, <a href="https://publications.waset.org/abstracts/search?q=MCF-7" title=" MCF-7"> MCF-7</a>, <a href="https://publications.waset.org/abstracts/search?q=caspase" title=" caspase"> caspase</a>, <a href="https://publications.waset.org/abstracts/search?q=cell%20cycle" title=" cell cycle"> cell cycle</a>, <a href="https://publications.waset.org/abstracts/search?q=acute%20toxicity" title=" acute toxicity"> acute toxicity</a> </p> <a href="https://publications.waset.org/abstracts/14365/new-quinazoline-derivative-exhibit-cytotoxic-effect-agaisnt-mcf-7-human-breast-cancer-cell" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/14365.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">442</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6</span> Design, Analysis and Simulation of a Lightweight Fire-Resistant Door</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Zainab%20Fadhil%20Al%20Toki">Zainab Fadhil Al Toki</a>, <a href="https://publications.waset.org/abstracts/search?q=Nader%20Ghareeb"> Nader Ghareeb</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study investigates how lightweight a fire resistance door will perform with under types of insulation materials. Data is initially collected from various websites, scientific books and research papers. Results show that different layers of insulation in a single door can perform better than one insulator. Furthermore, insulation materials that are lightweight, high strength and low thermal conductivity are the most preferred for fire-rated doors. Whereas heavy weight, low strength, and high thermal conductivity are least preferred for fire resistance doors. Fire-rated door specifications, theoretical test methodology, structural analysis, and comparison between five different models with diverse layers insulations are presented. Five different door models are being investigated with different insulation materials and arrangements. Model 1 contains an air gap between door layers. Model 2 includes phenolic foam, mild steel and polyurethane. Model 3 includes phenolic foam and glass wool. Model 4 includes polyurethane and glass wool. Model 5 includes only rock wool between the door layers. It is noticed that model 5 is the most efficient model, and its design is simple compared to other models. For this model, numerical calculations are performed to check its efficiency and the results are compared to data from experiments for validation. Good agreement was noticed. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=fire%20resistance" title="fire resistance">fire resistance</a>, <a href="https://publications.waset.org/abstracts/search?q=insulation" title=" insulation"> insulation</a>, <a href="https://publications.waset.org/abstracts/search?q=strength" title=" strength"> strength</a>, <a href="https://publications.waset.org/abstracts/search?q=thermal%20conductivity" title=" thermal conductivity"> thermal conductivity</a>, <a href="https://publications.waset.org/abstracts/search?q=lightweight" title=" lightweight"> lightweight</a>, <a href="https://publications.waset.org/abstracts/search?q=layers" title=" layers"> layers</a> </p> <a href="https://publications.waset.org/abstracts/186476/design-analysis-and-simulation-of-a-lightweight-fire-resistant-door" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/186476.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">51</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> Synthesis and Cytotoxic Activity of New Quinazolinone-Based Compounds against Human Breast Cancer Cell Line MCF-7</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Maryam%20Zahedifard">Maryam Zahedifard</a>, <a href="https://publications.waset.org/abstracts/search?q=Fadhil%20Lafta%20Faraj"> Fadhil Lafta Faraj</a>, <a href="https://publications.waset.org/abstracts/search?q=Maryam%20Hajrezaie"> Maryam Hajrezaie</a>, <a href="https://publications.waset.org/abstracts/search?q=Nazia%20Abdul%20Majid"> Nazia Abdul Majid</a>, <a href="https://publications.waset.org/abstracts/search?q=Mahmood%20Ameen%20Abdulla"> Mahmood Ameen Abdulla</a>, <a href="https://publications.waset.org/abstracts/search?q=Hapipah%20Mohd%20Ali"> Hapipah Mohd Ali</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In the current study, we prepared two new quinazoline schiff bases through condensation reaction of 2-aminobenzhydrazide with 5-bromosalicylaldehyde and 3-methoxy-5-bromosalicylaldehyde. The chemical structures of both newly synthesized compounds (1 and 2) were confirmed by FT-IR and X-ray crystallography studies. The cytotoxic effect of compounds was investigated against MCF-7 human breast cancer cells. MTT results showed that (1) and (2) decreased the viability of MCF-7 cells in a time-dependent manner, exhibiting an IC50 value of 3.23 卤 0.28 碌g/mL and 3.41 卤 0.34 碌g/mL, respectively, after a 72-hours treatment period. In contrast, they did not show significant anti-proliferative effect towards MCF-10A normal breast cells and WRL-68 normal liver cells. We found a perturbation in mitochondrial membrane potential and increased cytochrome c release from the mitochondria to the cytosol, suggesting an activation of apoptosis by compounds, which was confirmed by activation of the initiator caspase-9 and the executioner caspases-3/7. (1) was also able to trigger extrinsic pathway via activation of caspase-8 and inhibition of NF-魏B translocation. The acute toxicity test showed no toxicity effect of the compounds in rats. Our results showed that the selected synthesized compounds are highly potent to induce apoptosis in MCF-7 cells via either intrinsic or extrinsic mitochondrial pathway. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Quinazoline%20Schiff%20base" title="Quinazoline Schiff base">Quinazoline Schiff base</a>, <a href="https://publications.waset.org/abstracts/search?q=apoptosis" title=" apoptosis"> apoptosis</a>, <a href="https://publications.waset.org/abstracts/search?q=MCF-7%20human%20breast%20cancer%20cell%20line" title=" MCF-7 human breast cancer cell line"> MCF-7 human breast cancer cell line</a>, <a href="https://publications.waset.org/abstracts/search?q=caspase" title=" caspase"> caspase</a>, <a href="https://publications.waset.org/abstracts/search?q=NF-%CE%BAB%20translocation" title=" NF-魏B translocation"> NF-魏B translocation</a> </p> <a href="https://publications.waset.org/abstracts/13587/synthesis-and-cytotoxic-activity-of-new-quinazolinone-based-compounds-against-human-breast-cancer-cell-line-mcf-7" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/13587.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">492</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> Potential Effects of Climate Change on Streamflow, Based on the Occurrence of Severe Floods in Kelantan, East Coasts of Peninsular Malaysia River Basin</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Muhd.%20Barzani%20Gasim">Muhd. Barzani Gasim</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohd.%20Ekhwan%20Toriman"> Mohd. Ekhwan Toriman</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohd.%20Khairul%20Amri%20Kamarudin"> Mohd. Khairul Amri Kamarudin</a>, <a href="https://publications.waset.org/abstracts/search?q=Azman%20Azid"> Azman Azid</a>, <a href="https://publications.waset.org/abstracts/search?q=Siti%20Humaira%20Haron"> Siti Humaira Haron</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20Hafiz%20Md.%20Saad"> Muhammad Hafiz Md. Saad</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Malaysia is a country in Southeast Asia that constantly exposed to flooding and landslide. The disaster has caused some troubles such loss of property, loss of life and discomfort of people involved. This problem occurs as a result of climate change leading to increased stream flow rate as a result of disruption to regional hydrological cycles. The aim of the study is to determine hydrologic processes in the east coasts of Peninsular Malaysia, especially in Kelantan Basin. Parameterized to account for the spatial and temporal variability of basin characteristics and their responses to climate variability. For hydrological modeling of the basin, the Soil and Water Assessment Tool (SWAT) model such as relief, soil type, and its use, and historical daily time series of climate and river flow rates are studied. The interpretation of Landsat map/land uses will be applied in this study. The combined of SWAT and climate models, the system will be predicted an increase in future scenario climate precipitation, increase in surface runoff, increase in recharge and increase in the total water yield. As a result, this model has successfully developed the basin analysis by demonstrating analyzing hydrographs visually, good estimates of minimum and maximum flows and severe floods observed during calibration and validation periods. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=east%20coasts%20of%20Peninsular%20Malaysia" title="east coasts of Peninsular Malaysia">east coasts of Peninsular Malaysia</a>, <a href="https://publications.waset.org/abstracts/search?q=Kelantan%20river%20basin" title=" Kelantan river basin"> Kelantan river basin</a>, <a href="https://publications.waset.org/abstracts/search?q=minimum%20and%20maximum%20flows" title=" minimum and maximum flows"> minimum and maximum flows</a>, <a href="https://publications.waset.org/abstracts/search?q=severe%20floods" title=" severe floods"> severe floods</a>, <a href="https://publications.waset.org/abstracts/search?q=SWAT%20model" title=" SWAT model"> SWAT model</a> </p> <a href="https://publications.waset.org/abstracts/86824/potential-effects-of-climate-change-on-streamflow-based-on-the-occurrence-of-severe-floods-in-kelantan-east-coasts-of-peninsular-malaysia-river-basin" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/86824.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">262</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> The Use of a Miniature Bioreactor as Research Tool for Biotechnology Process Development</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20Zainuddin%20Arriafdi">Muhammad Zainuddin Arriafdi</a>, <a href="https://publications.waset.org/abstracts/search?q=Hamudah%20Hakimah%20Abdullah"> Hamudah Hakimah Abdullah</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohd%20Helmi%20Sani"> Mohd Helmi Sani</a>, <a href="https://publications.waset.org/abstracts/search?q=Wan%20Azlina%20Ahmad"> Wan Azlina Ahmad</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhd%20Nazrul%20Hisham%20Zainal%20Alam"> Muhd Nazrul Hisham Zainal Alam</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The biotechnology process development demands numerous experimental works. In laboratory environment, this is typically carried out using a shake flask platform. This paper presents the design and fabrication of a miniature bioreactor system as an alternative research tool for bioprocessing. The working volume of the reactor is 100 ml, and it is made of plastic. The main features of the reactor included stirring control, temperature control via the electrical heater, aeration strategy through a miniature air compressor, and online optical cell density (OD) sensing. All sensors and actuators integrated into the reactor was controlled using an Arduino microcontroller platform. In order to demonstrate the functionality of such miniature bioreactor concept, series of batch Saccharomyces cerevisiae fermentation experiments were performed under various glucose concentrations. Results attained from the fermentation experiments were utilized to solve the Monod equation constants, namely the saturation constant, Ks, and cells maximum growth rate, 渭max as to further highlight the usefulness of the device. The mixing capacity of the reactor was also evaluated. It was found that the results attained from the miniature bioreactor prototype were comparable to results achieved using a shake flask. The unique features of the device as compared to shake flask platform is that the reactor mixing condition is much more comparable to a lab-scale bioreactor setup. The prototype is also integrated with an online OD sensor, and as such, no sampling was needed to monitor the progress of the reaction performed. Operating cost and medium consumption are also low and thus, making it much more economical to be utilized for biotechnology process development compared to lab-scale bioreactors. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biotechnology" title="biotechnology">biotechnology</a>, <a href="https://publications.waset.org/abstracts/search?q=miniature%20bioreactor" title=" miniature bioreactor"> miniature bioreactor</a>, <a href="https://publications.waset.org/abstracts/search?q=research%20tools" title=" research tools"> research tools</a>, <a href="https://publications.waset.org/abstracts/search?q=Saccharomyces%20cerevisiae" title=" Saccharomyces cerevisiae"> Saccharomyces cerevisiae</a> </p> <a href="https://publications.waset.org/abstracts/120070/the-use-of-a-miniature-bioreactor-as-research-tool-for-biotechnology-process-development" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/120070.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">117</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Total Arterial Coronary Revascularization with Aorto-Bifemoral Bipopliteal Bypass: A Case Report</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nuruddin%20Mohammod%20Zahangir">Nuruddin Mohammod Zahangir</a>, <a href="https://publications.waset.org/abstracts/search?q=Syed%20Tanvir%20Ahmady"> Syed Tanvir Ahmady</a>, <a href="https://publications.waset.org/abstracts/search?q=Firoz%20Ahmed"> Firoz Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Mainul%20Kabir"> Mainul Kabir</a>, <a href="https://publications.waset.org/abstracts/search?q=Tamjid%20Mohammad%20Najmus%20Sakib%20Khan"> Tamjid Mohammad Najmus Sakib Khan</a>, <a href="https://publications.waset.org/abstracts/search?q=Nazmul%20Hossain"> Nazmul Hossain</a>, <a href="https://publications.waset.org/abstracts/search?q=Niaz%20Ahmed"> Niaz Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Madhava%20Janardhan%20Naik"> Madhava Janardhan Naik</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The management of combined Coronary Artery Disease and Peripheral Vascular Disease is a challenge and brings with it numerous clinical dilemmas.The 56 year old gentleman presented to our department with significant triple vessel disease with occluded lower end of aorta just before bifurcation and bilateral superficial femoral arteries. Operation was done on 11.03.14. The The Left Internal Mammary Artery (LIMA) and the Right Internal Mammary Artery (RIMA) were harvested in skeletonized manner. The free RIMA was then anastomosed with LIMA to make LIMA-RIMA Y. Cardio Pulmonary Bypass was then established and coronary artery bypass grafts performed. LIMA was anastomosed to the Left Anterior Descending artery. RIMA was anastomosed to Posterior Descending Artery, 1st and 2nd Obtuse Marginal arteries in a sequential manner. Abdomen was opened by midline incision. The infrarenal aorta exposed and was found to be severely diseased. A Vascular Clamp was applied infrarenally, aortotomy done and limited endarterectomy performed. An end-to-side anastomosis was done with upper end of PTFE synthetic Y-graft (14/7 mm) to the infarenal Aorta and the Clamp released. Good flow noted in both limbs of the graft. Patient was then slowly weaned off from Cardio Pulmonary Bypass without difficulty. The distal two limbs of the Y graft were passed to the groin through retroperitoneal tunnels and anastomosed end-to-side with the common femoral arteries. Saphenous vein was interposed between common femoral and popliteal arteries bilaterally through subfascial tunnels in both thigh. On 12th postoperative day he was discharged from hospital in good general condition. Follow up after 3 months of operation the patient is doing good and free of chest pain and claudication pain. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=total%20arterial" title="total arterial">total arterial</a>, <a href="https://publications.waset.org/abstracts/search?q=coronary%20revascularization" title=" coronary revascularization"> coronary revascularization</a>, <a href="https://publications.waset.org/abstracts/search?q=aorto-bifemoral%20bypass" title=" aorto-bifemoral bypass"> aorto-bifemoral bypass</a>, <a href="https://publications.waset.org/abstracts/search?q=bifemoro-bipopliteal%20bypass" title=" bifemoro-bipopliteal bypass"> bifemoro-bipopliteal bypass</a> </p> <a href="https://publications.waset.org/abstracts/12890/total-arterial-coronary-revascularization-with-aorto-bifemoral-bipopliteal-bypass-a-case-report" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/12890.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">472</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Optimal Capacitors Placement and Sizing Improvement Based on Voltage Reduction for Energy Efficiency</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Zilaila%20Zakaria">Zilaila Zakaria</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhd%20Azri%20Abdul%20Razak"> Muhd Azri Abdul Razak</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20Murtadha%20Othman"> Muhammad Murtadha Othman</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohd%20Ainor%20Yahya"> Mohd Ainor Yahya</a>, <a href="https://publications.waset.org/abstracts/search?q=Ismail%20Musirin"> Ismail Musirin</a>, <a href="https://publications.waset.org/abstracts/search?q=Mat%20Nasir%20Kari"> Mat Nasir Kari</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohd%20Fazli%20Osman"> Mohd Fazli Osman</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohd%20Zaini%20Hassan"> Mohd Zaini Hassan</a>, <a href="https://publications.waset.org/abstracts/search?q=Baihaki%20Azraee"> Baihaki Azraee</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Energy efficiency can be realized by minimizing the power loss with a sufficient amount of energy used in an electrical distribution system. In this report, a detailed analysis of the energy efficiency of an electric distribution system was carried out with an implementation of the optimal capacitor placement and sizing (OCPS). The particle swarm optimization (PSO) will be used to determine optimal location and sizing for the capacitors whereas energy consumption and power losses minimization will improve the energy efficiency. In addition, a certain number of busbars or locations are identified in advance before the PSO is performed to solve OCPS. In this case study, three techniques are performed for the pre-selection of busbar or locations which are the power-loss-index (PLI). The particle swarm optimization (PSO) is designed to provide a new population with improved sizing and location of capacitors. The total cost of power losses, energy consumption and capacitor installation are the components considered in the objective and fitness functions of the proposed optimization technique. Voltage magnitude limit, total harmonic distortion (THD) limit, power factor limit and capacitor size limit are the parameters considered as the constraints for the proposed of optimization technique. In this research, the proposed methodologies implemented in the MATLAB庐 software will transfer the information, execute the three-phase unbalanced load flow solution and retrieve then collect the results or data from the three-phase unbalanced electrical distribution systems modeled in the SIMULINK庐 software. Effectiveness of the proposed methods used to improve the energy efficiency has been verified through several case studies and the results are obtained from the test systems of IEEE 13-bus unbalanced electrical distribution system and also the practical electrical distribution system model of Sultan Salahuddin Abdul Aziz Shah (SSAAS) government building in Shah Alam, Selangor. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=particle%20swarm%20optimization" title="particle swarm optimization">particle swarm optimization</a>, <a href="https://publications.waset.org/abstracts/search?q=pre-determine%20of%20capacitor%20locations" title=" pre-determine of capacitor locations"> pre-determine of capacitor locations</a>, <a href="https://publications.waset.org/abstracts/search?q=optimal%20capacitors%20placement%20and%20sizing" title=" optimal capacitors placement and sizing"> optimal capacitors placement and sizing</a>, <a href="https://publications.waset.org/abstracts/search?q=unbalanced%20electrical%20distribution%20system" title=" unbalanced electrical distribution system"> unbalanced electrical distribution system</a> </p> <a href="https://publications.waset.org/abstracts/46202/optimal-capacitors-placement-and-sizing-improvement-based-on-voltage-reduction-for-energy-efficiency" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/46202.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">434</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Account <li><a href="https://waset.org/profile">My Account</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Explore <li><a href="https://waset.org/disciplines">Disciplines</a></li> <li><a href="https://waset.org/conferences">Conferences</a></li> <li><a href="https://waset.org/conference-programs">Conference Program</a></li> <li><a href="https://waset.org/committees">Committees</a></li> <li><a href="https://publications.waset.org">Publications</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Research <li><a href="https://publications.waset.org/abstracts">Abstracts</a></li> <li><a href="https://publications.waset.org">Periodicals</a></li> <li><a href="https://publications.waset.org/archive">Archive</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Open Science <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Philosophy.pdf">Open Science Philosophy</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Award.pdf">Open Science Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Society-Open-Science-and-Open-Innovation.pdf">Open Innovation</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Postdoctoral-Fellowship-Award.pdf">Postdoctoral Fellowship Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Scholarly-Research-Review.pdf">Scholarly Research Review</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Support <li><a href="https://waset.org/page/support">Support</a></li> <li><a href="https://waset.org/profile/messages/create">Contact Us</a></li> <li><a href="https://waset.org/profile/messages/create">Report Abuse</a></li> </ul> </div> </div> </div> </div> </div> <div class="container text-center"> <hr style="margin-top:0;margin-bottom:.3rem;"> <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" class="text-muted small">Creative Commons Attribution 4.0 International License</a> <div id="copy" class="mt-2">&copy; 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