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Northeastern University | Business Administration - Academia.edu

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Satisfaction and Quality Health Services: An Investigation from Private Hospitals of Karachi, Pakistan</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Patient satisfaction is the critical issue for healthcare providers. Health care organizations are working in a competitive environment. In these days hospital needs to enhance the level of satisfaction if they want to remain in the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_10587550" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Patient satisfaction is the critical issue for healthcare providers. Health care organizations are working in a competitive environment. In these days hospital needs to enhance the level of satisfaction if they want to remain in the competition with other hospitals. Patient satisfaction is basically satisfying patients&#39; expectations and understanding their needs. Patients&#39; feedback can affect the overall quality, to improve organizational learning and development agenda and provide an opportunity. The aim of this study was to determine the patient satisfaction at Private hospital of Karachi for the in-patient departments. This study concludes that the majority of the patients are satisfied with the services provided by the in-patient departments of selected Private hospitals of Karachi. Specially, the patients and their attendants&#39; are very much satisfied from Patient ward services, Laboratories services, food services, reception staff services, welfare services &amp; healthcare services provided by the hospitals to the in-patient departments, therefore, this shows significant impact on overall patients&#39; satisfaction. The strengths of the healthcare organizations as highlighted by patients must be continuing. However, some services need more care and focus when overall planning &amp; strategies&#39; will be made for planning &amp; managing the health care system.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/10587550" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="8405ebd4e8e1764d1da52c6d330a0dd6" rel="nofollow" data-download="{&quot;attachment_id&quot;:36549760,&quot;asset_id&quot;:10587550,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/36549760/download_file?st=MTczMzk1ODAyNyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="25895333" href="https://neu.academia.edu/Ng%E1%BB%8DcKokoro">Ngọc Kokoro</a><script data-card-contents-for-user="25895333" type="text/json">{"id":25895333,"first_name":"Ngọc","last_name":"Kokoro","domain_name":"neu","page_name":"NgọcKokoro","display_name":"Ngọc Kokoro","profile_url":"https://neu.academia.edu/Ng%E1%BB%8DcKokoro","photo":"https://0.academia-photos.com/25895333/9958945/11105423/s65_ng_c.kokoro.jpg"}</script></span></span></li><li class="js-paper-rank-work_10587550 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="10587550"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 10587550, container: ".js-paper-rank-work_10587550", }); 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$(".js-view-count[data-work-id=10587550]").text(description); $(".js-view-count-work_10587550").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_10587550").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="10587550"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">3</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="39" href="https://www.academia.edu/Documents/in/Marketing">Marketing</a>,&nbsp;<script data-card-contents-for-ri="39" type="text/json">{"id":39,"name":"Marketing","url":"https://www.academia.edu/Documents/in/Marketing","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="144052" href="https://www.academia.edu/Documents/in/Patient_Satisfaction">Patient Satisfaction</a>,&nbsp;<script data-card-contents-for-ri="144052" type="text/json">{"id":144052,"name":"Patient Satisfaction","url":"https://www.academia.edu/Documents/in/Patient_Satisfaction","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="1363673" href="https://www.academia.edu/Documents/in/Healthcare_Services">Healthcare Services</a><script data-card-contents-for-ri="1363673" type="text/json">{"id":1363673,"name":"Healthcare Services","url":"https://www.academia.edu/Documents/in/Healthcare_Services","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=10587550]'), work: {"id":10587550,"title":"Patients' Satisfaction and Quality Health Services: An Investigation from Private Hospitals of Karachi, Pakistan","created_at":"2015-02-06T23:42:39.638-08:00","owner_id":25895333,"url":"https://www.academia.edu/10587550/Patients_Satisfaction_and_Quality_Health_Services_An_Investigation_from_Private_Hospitals_of_Karachi_Pakistan","slug":"Patients_Satisfaction_and_Quality_Health_Services_An_Investigation_from_Private_Hospitals_of_Karachi_Pakistan","dom_id":"work_10587550","summary":"Patient satisfaction is the critical issue for healthcare providers. Health care organizations are working in a competitive environment. In these days hospital needs to enhance the level of satisfaction if they want to remain in the competition with other hospitals. Patient satisfaction is basically satisfying patients' expectations and understanding their needs. Patients' feedback can affect the overall quality, to improve organizational learning and development agenda and provide an opportunity. The aim of this study was to determine the patient satisfaction at Private hospital of Karachi for the in-patient departments. This study concludes that the majority of the patients are satisfied with the services provided by the in-patient departments of selected Private hospitals of Karachi. Specially, the patients and their attendants' are very much satisfied from Patient ward services, Laboratories services, food services, reception staff services, welfare services \u0026 healthcare services provided by the hospitals to the in-patient departments, therefore, this shows significant impact on overall patients' satisfaction. The strengths of the healthcare organizations as highlighted by patients must be continuing. 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The objective of this study is twofold: first to identify the constituents that mold... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_36876306" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The successful implementation of an integrated supply chain strategy enhances total control over the operations and thus enhances speed and flexibility. The objective of this study is twofold: first to identify the constituents that mold the fast fashion retailing business model, and second to discuss how global leader of fast fashion retailing Inditex-Zara&#39;s product offering is strongly supported by integration of various supply chain operations. The findings suggest that vertical integration through ownership of various operational stages including product design and development, production operation, logistics and distribution channel; appropriate sourcing strategy to meet product needs; application of process/product modularity practices in product design, material procurement and manufacturing to ensure manufacturing flexibility; flexible logistics capability; and all of these seamlessly integrated and coordinated by a centralized IT infrastructure can significantly raise overall supply chain flexibility and responsiveness. Inditex-Zara&#39;s super-responsive supply chain reduces &#39;bullwhip effect&#39;, order-to-delivery lead time to stores, ensures lean inventory and high level of responsiveness to adapt and deliver products to stores with latest fashion trends and customer feedbacks at a rapid speed. Thus Inditex-Zara is able to successfully counter the negative effects of short product life cycles, high product variety, demand uncertainty and thus able to closely match product supply to the stores with market demand. This contributes to lower inventory backlogs; avoid mark-down losses and/or inventory stock out.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/36876306" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="9fbe1967b09a16c27b51796b8ffa22bf" rel="nofollow" data-download="{&quot;attachment_id&quot;:56831232,&quot;asset_id&quot;:36876306,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/56831232/download_file?st=MTczMzk1ODAyNyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="83258680" href="https://neu.academia.edu/HongChinhDo">Hong Chinh Do</a><script data-card-contents-for-user="83258680" type="text/json">{"id":83258680,"first_name":"Hong Chinh","last_name":"Do","domain_name":"neu","page_name":"HongChinhDo","display_name":"Hong Chinh Do","profile_url":"https://neu.academia.edu/HongChinhDo","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_36876306 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="36876306"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 36876306, container: ".js-paper-rank-work_36876306", }); 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As such, whistleblowing connects with sustainability, and in particular with the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_107316250" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">There is a consensus in the literature that whistleblowing can operate as an instrument for deterring wrongdoing and promoting transparency in organizations. As such, whistleblowing connects with sustainability, and in particular with the UN sustainable development goals (SDG 16, reducing corruption) for transparency and accountability in public sector entities. The purpose of this study is to explore the attitudes of public servants in Greek municipalities before and after the introduction of the “EU Directive on Whistleblowing”. In particular, we investigate how the political, legal, organizational, and cultural environment within which Greek municipalities operate shapes negative employee attitudes toward whistleblowing. Primary data was collected through in-depth interviews with municipal employees from 2020 to 2023 before and after the incorporation of the “EU Directive on Whistleblowing” into the Greek legal system. 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type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="447741" href="https://www.academia.edu/Documents/in/Peritoneal_Dialysis">Peritoneal Dialysis</a>,&nbsp;<script data-card-contents-for-ri="447741" type="text/json">{"id":447741,"name":"Peritoneal Dialysis","url":"https://www.academia.edu/Documents/in/Peritoneal_Dialysis","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="869175" href="https://www.academia.edu/Documents/in/Ovary">Ovary</a><script data-card-contents-for-ri="869175" type="text/json">{"id":869175,"name":"Ovary","url":"https://www.academia.edu/Documents/in/Ovary","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=53751845]'), work: {"id":53751845,"title":"Why remove, when you can 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failure","url":"https://www.academia.edu/Documents/in/Equipment_failure"},{"id":3194201,"name":"Fallopian tubes","url":"https://www.academia.edu/Documents/in/Fallopian_tubes"}],"publication_year":2014,"publication_year_with_fallback":2014,"paper_rank":null,"all_time_views":3,"active_discussion":{}}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_62877239" data-work_id="62877239" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/62877239/Recent_Advances_in_Flower_Pollination_Algorithm">Recent Advances in Flower Pollination Algorithm</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Flower Pollination Algorithm (FPA) is a nature inspired algorithm based on pollination process of plants. Recently, FPA has become a popular algorithm in the evolutionary computation field due to its superiority to many other algorithms.... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_62877239" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Flower Pollination Algorithm (FPA) is a nature inspired algorithm based on pollination process of plants. Recently, FPA has become a popular algorithm in the evolutionary computation field due to its superiority to many other algorithms. As a consequence, in this paper, FPA, its improvements, its hybridization and applications in many fields, such as operations research, engineering and computer science, are discussed and analyzed. Based on its applications in the field of optimization it was seemed that this algorithm has a better convergence speed compared to other algorithms. The survey investigates the difference between FPA versions as well as its applications. To add to this, several future improvements are suggested.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/62877239" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="d1c904b6dd7dd9bb77c3c90c41e1c5b2" rel="nofollow" data-download="{&quot;attachment_id&quot;:75501466,&quot;asset_id&quot;:62877239,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/75501466/download_file?st=MTczMzk1ODAyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="140393508" href="https://neu.academia.edu/NabilDiab">Nabil Diab</a><script data-card-contents-for-user="140393508" type="text/json">{"id":140393508,"first_name":"Nabil","last_name":"Diab","domain_name":"neu","page_name":"NabilDiab","display_name":"Nabil Diab","profile_url":"https://neu.academia.edu/NabilDiab","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_62877239 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="62877239"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 62877239, container: ".js-paper-rank-work_62877239", }); });</script></li><li class="js-percentile-work_62877239 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 62877239; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_62877239"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_62877239 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="62877239"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 62877239; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=62877239]").text(description); $(".js-view-count-work_62877239").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_62877239").removeClass('hidden') })</script></div></li></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_62877240" data-work_id="62877240" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/62877240/Cognitive_Predictors_of_the_Value_of_One_s_Own_Life_in_Students">Cognitive Predictors of the Value of One’s Own Life in Students</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The aim of the article is to present the findings of the empirical research on the feeling of the value of one&#39;s own life (VOL) in students. Experiencing the feeling of VOL is understood to be the intended activity of an individual... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_62877240" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The aim of the article is to present the findings of the empirical research on the feeling of the value of one&#39;s own life (VOL) in students. Experiencing the feeling of VOL is understood to be the intended activity of an individual through which they reinforce (strengthen) their psychological and personal being. A presumption about the important role of a cognitive factor in experiencing the feeling of VOL in students was tested. In the manifestation of VOL, the role of such a cognitive factor as basic beliefs was investigated. Methods. Basic beliefs were diagnosed using the modified questionnaire by R. Janoff-Bulman. To diagnose the parameters of the feeling of VOL, the author&#39;s questionnaire was used. 286 students took part in the testing. The correlations between the scores of two questionnaires were calculated. Logistic regression was used. The results of the research.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/62877240" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="2bfd63ebf11435dd99e9ae87a910f349" rel="nofollow" data-download="{&quot;attachment_id&quot;:75501467,&quot;asset_id&quot;:62877240,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/75501467/download_file?st=MTczMzk1ODAyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="140393508" href="https://neu.academia.edu/NabilDiab">Nabil Diab</a><script data-card-contents-for-user="140393508" type="text/json">{"id":140393508,"first_name":"Nabil","last_name":"Diab","domain_name":"neu","page_name":"NabilDiab","display_name":"Nabil Diab","profile_url":"https://neu.academia.edu/NabilDiab","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_62877240 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="62877240"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 62877240, container: ".js-paper-rank-work_62877240", }); });</script></li><li class="js-percentile-work_62877240 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 62877240; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_62877240"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_62877240 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="62877240"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 62877240; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=62877240]").text(description); $(".js-view-count-work_62877240").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_62877240").removeClass('hidden') })</script></div></li></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_79441966" data-work_id="79441966" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/79441966/Transporter_Associated_with_Antigen_Processing_Like_ABCB9_Stably_Expressed_in_Chinese_Hamster_Ovary_K1_Cells_Is_Sorted_to_the_Microdomains_of_Lysosomal_Membranes">Transporter Associated with Antigen Processing-Like (ABCB9) Stably Expressed in Chinese Hamster Ovary-K1 Cells Is Sorted to the Microdomains of Lysosomal Membranes</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The carboxyl terminus of a human ATP-binding cassette (ABC) transporter, transporter associated with antigen processing (TAP)-like (TAPL), was tagged with green fluorescence protein (GFP), and the resulting fusion protein (TAPL-GFP) was... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_79441966" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The carboxyl terminus of a human ATP-binding cassette (ABC) transporter, transporter associated with antigen processing (TAP)-like (TAPL), was tagged with green fluorescence protein (GFP), and the resulting fusion protein (TAPL-GFP) was stably expressed in Chinese hamster ovary (CHO)-K1 cells. The GFP signal was co-localized with that of LysoTracker but not that of MitoTracker, as visualized under a microscope. TAPL-GFP was co-sedimented with lysosomal marker cathepsin D on Percoll density gradient centrifugation. These results indicated that TAPL is a lysosomal ABC transporter but not a mitochondrial one. It was not solubilized completely with a non-ionic detergent under ice-cold conditions, and was co-sedimented with flotillin-1 on sucrose density gradient centrifugation. A similar result was obtained with high pH-treatment. Furthermore, treatment with methyl-b b-cyclodextrin resulted in an altered distribution of TAPL-GFP. These results suggest that TAPL may be localized to the microdomains (lipid rafts) of lysosomal membranes enriched in cholesterol.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/79441966" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="b9a9f5b54ea6f85d3b4b17b22d137c51" rel="nofollow" data-download="{&quot;attachment_id&quot;:86155597,&quot;asset_id&quot;:79441966,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/86155597/download_file?st=MTczMzk1ODAyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="140393508" href="https://neu.academia.edu/NabilDiab">Nabil Diab</a><script data-card-contents-for-user="140393508" type="text/json">{"id":140393508,"first_name":"Nabil","last_name":"Diab","domain_name":"neu","page_name":"NabilDiab","display_name":"Nabil Diab","profile_url":"https://neu.academia.edu/NabilDiab","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_79441966 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="79441966"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 79441966, container: ".js-paper-rank-work_79441966", }); 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The GFP signal was co-localized with that of LysoTracker but not that of MitoTracker, as visualized under a microscope. TAPL-GFP was co-sedimented with lysosomal marker cathepsin D on Percoll density gradient centrifugation. These results indicated that TAPL is a lysosomal ABC transporter but not a mitochondrial one. It was not solubilized completely with a non-ionic detergent under ice-cold conditions, and was co-sedimented with flotillin-1 on sucrose density gradient centrifugation. A similar result was obtained with high pH-treatment. Furthermore, treatment with methyl-b b-cyclodextrin resulted in an altered distribution of TAPL-GFP. These results suggest that TAPL may be localized to the microdomains (lipid rafts) of lysosomal membranes enriched in cholesterol.","publication":"Biological \u0026 Pharmaceutical Bulletin","publication_with_fallback":"Biological \u0026 Pharmaceutical Bulletin","downloadable_attachments":[{"id":86155597,"asset_id":79441966,"asset_type":"Work","always_allow_download":false,"scribd_thumbnail_url":"https://attachments.academia-assets.com/86155597/thumbnails/1.jpg","download_url":"https://d1wqtxts1xzle7.cloudfront.net/86155597/_pdf-libre.pdf?1652962839=\u0026response-content-disposition=attachment%3B+filename%3DTransporter_Associated_with_Antigen_Proc.pdf\u0026Expires=1733961628\u0026Signature=ZFdUFpcDeoIbQRxIXS7SbIcqtNm0F6Md-xVcT4e30O1lVRicqgNUay7H6yhJA8TgilDA-wzQMlRxOHpnKvWAELVLPGoiiT-lEejOKjO9OLSuQYGI9kRPnQwyxO0V~ocWWr4EgN694f-F5Q~Lkb2iKNvAS6WIWbktZkUJmu0hPNw4h-RizhE5CnBnEFaCKTAOZHgPvn0v0og9pRsFYGYndVMc9UtFf2UeC1xu37ozYEC0fUvHdnEaFoMgMrZbPDddQadRqlj0S3TfRrYq~Ny-9llAeyXyzi8XjvP-GJMvu2ukYtXRgU0NynUKaCKigmSu-tuXW1CROJmOuEpU210SNQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA","download_file_url":"https://www.academia.edu/attachments/86155597/download_file?st=MTczMzk1ODAyOCw4LjIyMi4yMDguMTQ2&","full_thumbnail_url":"https://0.academia-photos.com/attachment_thumbnails/86155597/mini_magick20220522-1430-1fx4xlg.png?1653208033"}],"downloadable_attachments_with_full_thumbnails":[{"id":86155597,"asset_id":79441966,"asset_type":"Work","always_allow_download":false,"scribd_thumbnail_url":"https://attachments.academia-assets.com/86155597/thumbnails/1.jpg","download_url":"https://d1wqtxts1xzle7.cloudfront.net/86155597/_pdf-libre.pdf?1652962839=\u0026response-content-disposition=attachment%3B+filename%3DTransporter_Associated_with_Antigen_Proc.pdf\u0026Expires=1733961628\u0026Signature=ZFdUFpcDeoIbQRxIXS7SbIcqtNm0F6Md-xVcT4e30O1lVRicqgNUay7H6yhJA8TgilDA-wzQMlRxOHpnKvWAELVLPGoiiT-lEejOKjO9OLSuQYGI9kRPnQwyxO0V~ocWWr4EgN694f-F5Q~Lkb2iKNvAS6WIWbktZkUJmu0hPNw4h-RizhE5CnBnEFaCKTAOZHgPvn0v0og9pRsFYGYndVMc9UtFf2UeC1xu37ozYEC0fUvHdnEaFoMgMrZbPDddQadRqlj0S3TfRrYq~Ny-9llAeyXyzi8XjvP-GJMvu2ukYtXRgU0NynUKaCKigmSu-tuXW1CROJmOuEpU210SNQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA","download_file_url":"https://www.academia.edu/attachments/86155597/download_file?st=MTczMzk1ODAyOCw4LjIyMi4yMDguMTQ2&","full_thumbnail_url":"https://0.academia-photos.com/attachment_thumbnails/86155597/mini_magick20220522-1430-1fx4xlg.png?1653208033"}],"has_pdf":true,"has_fulltext":true,"page_count":5,"ordered_authors":[{"id":140393508,"first_name":"Nabil","last_name":"Diab","domain_name":"neu","page_name":"NabilDiab","display_name":"Nabil Diab","profile_url":"https://neu.academia.edu/NabilDiab","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":5541,"name":"Plant Biology","url":"https://www.academia.edu/Documents/in/Plant_Biology","nofollow":false},{"id":3789884,"name":"Pharmacology and pharmaceutical sciences","url":"https://www.academia.edu/Documents/in/Pharmacology_and_pharmaceutical_sciences","nofollow":false}],"publication_year":2011,"publication_year_with_fallback":2011,"paper_rank":null,"all_time_views":4,"active_discussion":{}}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_79441968" data-work_id="79441968" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/79441968/Advantage_of_antithymocyte_globulin_induction_in_sensitized_kidney_recipients_a_randomized_prospective_study_comparing_induction_with_and_without_antithymocyte_globulin">Advantage of antithymocyte globulin induction in sensitized kidney recipients: a randomized prospective study comparing induction with and without antithymocyte globulin</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">sion; induction therapy; renal transplantation; triple therapy Background. Sensitized kidney allograft recipients require special management to improve their outcome. One strategy is heavy immunosuppression with antilymphocyte antibodies.... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_79441968" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">sion; induction therapy; renal transplantation; triple therapy Background. Sensitized kidney allograft recipients require special management to improve their outcome. One strategy is heavy immunosuppression with antilymphocyte antibodies. Controversy continues about lymphocytotoxic antibodies are known to be at a high Methods. In this study, we randomized sensitized renal risk of encountering several difficulties. These include transplant recipients, who received prophylactic treata positive crossmatch, a primary non-functioning alloment with or without antithymocyte globulin (ATG), graft, an acute rejection episode and, in the long-term, in addition to a standard triple regimen consisting of a reduced graft survival [1-3]. Many strategies have cyclosporin, steroids and azathioprine at ATG discontibeen designed to manage sensitized recipients; among nuation. The induction treatment consisted of a lowthese, the use of a heavy prophylactic immunosuppresdose ATG course over 10 days. Randomization was sion has been proposed, adding antilymphocyte globustratified on the maximum PRA, according to the five lin (ALG), antithymocyte globulin (ATG) or antifollowing classes: 5%&lt;PRA∏20%, 20%&lt;PRA∏40%, CD3 monoclonal antibodies (OKT3), in what are 40%&lt;PRA∏60%, 60%&lt;PRA∏80% and 80%&lt; named induction therapies. Although heavy immuno-PRA∏100%. suppression has been proved to be effective [4], the Results. Eighty nine patients were enrolled: 47 patients actual advantage of these induction therapies may be received ATG and 42 did not. ATG induction lowered questioned with regard to some other studies which the incidence of biopsy-proven acute rejection episodes have reported only a very modest effect on overall from 64 to 38%, increased 1 year graft survival from graft survival [5]. Protocols with antilymphocyte 76 to 89% and was associated with a higher 1 year antibodies have been designed mainly to delay the inulin clearance (37±15 vs 49±18 ml/min). ATGintroduction of cyclosporin and its associated nephroassociated side effects were restricted to leucopenia and toxicity [6-8]. Patients suffering from delayed graft thrombocytopenia, whereas bacterial and viral infecfunction may represent a subgroup which would benefit tions, gammopathies and cancers did not occur more from sequential therapies [9]. Heavy immunosuppresfrequently. ATG induction benefited all sensitized sive protocols with antilymphocyte antibodies and patients, and not only the hypersensitized patients. cyclosporin given simultaneously have already been Conclusions. We conclude that ATG induction is beneproposed [10], but not always in comparative studies ficial for all sensitized patients, regardless of their level [11]. Most of the comparisons were based on the of sensitization, with regard to acute rejection episodes, prophylactic use of ALG and OKT3, neither of which graft survival and graft function. Low-dose ATG is has proved to be superior. Finally, information on sufficient and prevents additional complications. sensitized patients remains scarce [12].There is no evidence to suggest that highly sensitized patients Key words: antithymocyte globulin; immunosuppresrequire more prophylactic immunosuppression than the less sensitized patients and, moreover, at present we do not know the effect of induction therapies in</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/79441968" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="91700d8ec3f8844206115007a965904d" rel="nofollow" data-download="{&quot;attachment_id&quot;:86155598,&quot;asset_id&quot;:79441968,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/86155598/download_file?st=MTczMzk1ODAyOSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="140393508" href="https://neu.academia.edu/NabilDiab">Nabil Diab</a><script data-card-contents-for-user="140393508" type="text/json">{"id":140393508,"first_name":"Nabil","last_name":"Diab","domain_name":"neu","page_name":"NabilDiab","display_name":"Nabil Diab","profile_url":"https://neu.academia.edu/NabilDiab","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_79441968 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="79441968"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 79441968, container: ".js-paper-rank-work_79441968", }); 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$(".js-view-count[data-work-id=79441968]").text(description); $(".js-view-count-work_79441968").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_79441968").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="79441968"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">12</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="9003" href="https://www.academia.edu/Documents/in/Kidney_transplantation">Kidney transplantation</a>,&nbsp;<script data-card-contents-for-ri="9003" type="text/json">{"id":9003,"name":"Kidney transplantation","url":"https://www.academia.edu/Documents/in/Kidney_transplantation","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="12426" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a>,&nbsp;<script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>,&nbsp;<script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="58379" href="https://www.academia.edu/Documents/in/Renal_transplantation">Renal transplantation</a><script data-card-contents-for-ri="58379" type="text/json">{"id":58379,"name":"Renal transplantation","url":"https://www.academia.edu/Documents/in/Renal_transplantation","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=79441968]'), work: {"id":79441968,"title":"Advantage of antithymocyte globulin induction in sensitized kidney recipients: a randomized prospective study comparing induction with and without antithymocyte globulin","created_at":"2022-05-19T05:03:06.345-07:00","owner_id":140393508,"url":"https://www.academia.edu/79441968/Advantage_of_antithymocyte_globulin_induction_in_sensitized_kidney_recipients_a_randomized_prospective_study_comparing_induction_with_and_without_antithymocyte_globulin","slug":"Advantage_of_antithymocyte_globulin_induction_in_sensitized_kidney_recipients_a_randomized_prospective_study_comparing_induction_with_and_without_antithymocyte_globulin","dom_id":"work_79441968","summary":"sion; induction therapy; renal transplantation; triple therapy Background. Sensitized kidney allograft recipients require special management to improve their outcome. One strategy is heavy immunosuppression with antilymphocyte antibodies. Controversy continues about lymphocytotoxic antibodies are known to be at a high Methods. In this study, we randomized sensitized renal risk of encountering several difficulties. These include transplant recipients, who received prophylactic treata positive crossmatch, a primary non-functioning alloment with or without antithymocyte globulin (ATG), graft, an acute rejection episode and, in the long-term, in addition to a standard triple regimen consisting of a reduced graft survival [1-3]. Many strategies have cyclosporin, steroids and azathioprine at ATG discontibeen designed to manage sensitized recipients; among nuation. The induction treatment consisted of a lowthese, the use of a heavy prophylactic immunosuppresdose ATG course over 10 days. Randomization was sion has been proposed, adding antilymphocyte globustratified on the maximum PRA, according to the five lin (ALG), antithymocyte globulin (ATG) or antifollowing classes: 5%\u003cPRA∏20%, 20%\u003cPRA∏40%, CD3 monoclonal antibodies (OKT3), in what are 40%\u003cPRA∏60%, 60%\u003cPRA∏80% and 80%\u003c named induction therapies. Although heavy immuno-PRA∏100%. suppression has been proved to be effective [4], the Results. Eighty nine patients were enrolled: 47 patients actual advantage of these induction therapies may be received ATG and 42 did not. ATG induction lowered questioned with regard to some other studies which the incidence of biopsy-proven acute rejection episodes have reported only a very modest effect on overall from 64 to 38%, increased 1 year graft survival from graft survival [5]. Protocols with antilymphocyte 76 to 89% and was associated with a higher 1 year antibodies have been designed mainly to delay the inulin clearance (37±15 vs 49±18 ml/min). ATGintroduction of cyclosporin and its associated nephroassociated side effects were restricted to leucopenia and toxicity [6-8]. Patients suffering from delayed graft thrombocytopenia, whereas bacterial and viral infecfunction may represent a subgroup which would benefit tions, gammopathies and cancers did not occur more from sequential therapies [9]. Heavy immunosuppresfrequently. ATG induction benefited all sensitized sive protocols with antilymphocyte antibodies and patients, and not only the hypersensitized patients. cyclosporin given simultaneously have already been Conclusions. We conclude that ATG induction is beneproposed [10], but not always in comparative studies ficial for all sensitized patients, regardless of their level [11]. Most of the comparisons were based on the of sensitization, with regard to acute rejection episodes, prophylactic use of ALG and OKT3, neither of which graft survival and graft function. Low-dose ATG is has proved to be superior. Finally, information on sufficient and prevents additional complications. sensitized patients remains scarce [12].There is no evidence to suggest that highly sensitized patients Key words: antithymocyte globulin; immunosuppresrequire more prophylactic immunosuppression than the less sensitized patients and, moreover, at present we do not know the effect of induction therapies in","publication":"Nephrology Dialysis Transplantation","publication_with_fallback":"Nephrology Dialysis 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js-work-link" href="https://www.academia.edu/79441976/Celiac_Disease_Overlooked_in_a_Patient_With_Becker_Muscle_Dystrophy">Celiac Disease Overlooked in a Patient With Becker Muscle Dystrophy</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Becker Muscle dystrophy is a regressive orphan X-linked disease that will progress into hypotonia and muscle weakness involving the skeletal as well as the cardiac muscles, with increased CPK blood levels and hypertransaminasemia.... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_79441976" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Becker Muscle dystrophy is a regressive orphan X-linked disease that will progress into hypotonia and muscle weakness involving the skeletal as well as the cardiac muscles, with increased CPK blood levels and hypertransaminasemia. Patients with Becker muscle dystrophy rarely present symptoms at early age. Here we present a patient with Becker dystrophy, increased ALT and marked digestive symptoms. The digestive symptoms were proven to be linked to a celiac disease that was overlooked due to the presence of the muscle dystrophy. It is not uncommon in areas with very high consanguinity rates to have a patient presenting two rare genetic diseases at the same time. The initiation of a gluten free diet helped improve the symptoms and the wellbeing of this patient.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/79441976" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="4c1e4430ce1869f7dc02a3220a52ed26" rel="nofollow" data-download="{&quot;attachment_id&quot;:86155599,&quot;asset_id&quot;:79441976,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/86155599/download_file?st=MTczMzk1ODAyOSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="140393508" href="https://neu.academia.edu/NabilDiab">Nabil Diab</a><script data-card-contents-for-user="140393508" type="text/json">{"id":140393508,"first_name":"Nabil","last_name":"Diab","domain_name":"neu","page_name":"NabilDiab","display_name":"Nabil Diab","profile_url":"https://neu.academia.edu/NabilDiab","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_79441976 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="79441976"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 79441976, container: ".js-paper-rank-work_79441976", }); 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Patients with Becker muscle dystrophy rarely present symptoms at early age. Here we present a patient with Becker dystrophy, increased ALT and marked digestive symptoms. The digestive symptoms were proven to be linked to a celiac disease that was overlooked due to the presence of the muscle dystrophy. It is not uncommon in areas with very high consanguinity rates to have a patient presenting two rare genetic diseases at the same time. 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}); });</script></span><script>$(function() { $(".js-view-count-work_88353504").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="88353504"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">2</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>,&nbsp;<script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="413301" href="https://www.academia.edu/Documents/in/Perforation">Perforation</a><script data-card-contents-for-ri="413301" 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Diab","profile_url":"https://neu.academia.edu/NabilDiab","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine","nofollow":false},{"id":413301,"name":"Perforation","url":"https://www.academia.edu/Documents/in/Perforation","nofollow":false}],"publication_year":2019,"publication_year_with_fallback":2019,"paper_rank":null,"all_time_views":5,"active_discussion":{}}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_88353507" data-work_id="88353507" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/88353507/Pediatric_appendectomy_in_the_developing_countries_How_does_it_differ_from_the_international_experience">Pediatric appendectomy in the developing countries. How does it differ from the international experience?</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Introduction: A review of the English literature indicates the faint superiority of laparoscopic (LA) over open appendectomy (OA) in the pediatric population; however, a developing-country&#39;s experience in the field is not available yet.... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_88353507" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Introduction: A review of the English literature indicates the faint superiority of laparoscopic (LA) over open appendectomy (OA) in the pediatric population; however, a developing-country&#39;s experience in the field is not available yet. This study presents our experience in LA versus OA over the last 7 years in one university hospital in Lebanon and compares our results to the international ones. Method: A single center retrospective study was done including all patients aged less than 15 years who underwent appendectomy. A description of each operative technique is presented. Patients&#39; characteristics, intraoperative finding, operative timing (OT), length of stay (LOS) and short term postoperative complications including surgical site infection (SSI) rate, intra-abdominal abscess formation (IAA) rate and reoperation rate were all studied. Statistical analysis was done using Chi-square or Fisher&#39;s exact test, as for continuous, Student&#39;s t test was used or one-way ANOVA in case of more than 2 categories. Result: Appendectomy was performed in 84 patients. 52 patients underwent OA through a Rocky Davis incision, and 32 patients underwent a LA. We found an advantage of LA over OA in reducing SSI, otherwise both approaches were similar. Conclusion: In accordance with international results, in our experience, LA is superior to OA only with regards to SSI.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/88353507" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="3c84043c6a44ef63e56bfc584556fbe7" rel="nofollow" data-download="{&quot;attachment_id&quot;:92342134,&quot;asset_id&quot;:88353507,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/92342134/download_file?st=MTczMzk1ODAyOSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="140393508" href="https://neu.academia.edu/NabilDiab">Nabil Diab</a><script data-card-contents-for-user="140393508" type="text/json">{"id":140393508,"first_name":"Nabil","last_name":"Diab","domain_name":"neu","page_name":"NabilDiab","display_name":"Nabil Diab","profile_url":"https://neu.academia.edu/NabilDiab","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_88353507 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="88353507"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 88353507, container: ".js-paper-rank-work_88353507", }); });</script></li><li class="js-percentile-work_88353507 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 88353507; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_88353507"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_88353507 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="88353507"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 88353507; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=88353507]").text(description); $(".js-view-count-work_88353507").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_88353507").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="88353507"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">3</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="647" href="https://www.academia.edu/Documents/in/Surgery">Surgery</a>,&nbsp;<script data-card-contents-for-ri="647" type="text/json">{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>,&nbsp;<script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="988280" href="https://www.academia.edu/Documents/in/Abscess">Abscess</a><script data-card-contents-for-ri="988280" type="text/json">{"id":988280,"name":"Abscess","url":"https://www.academia.edu/Documents/in/Abscess","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=88353507]'), work: {"id":88353507,"title":"Pediatric appendectomy in the developing countries. How does it differ from the international experience?","created_at":"2022-10-12T09:51:02.647-07:00","owner_id":140393508,"url":"https://www.academia.edu/88353507/Pediatric_appendectomy_in_the_developing_countries_How_does_it_differ_from_the_international_experience","slug":"Pediatric_appendectomy_in_the_developing_countries_How_does_it_differ_from_the_international_experience","dom_id":"work_88353507","summary":"Introduction: A review of the English literature indicates the faint superiority of laparoscopic (LA) over open appendectomy (OA) in the pediatric population; however, a developing-country's experience in the field is not available yet. This study presents our experience in LA versus OA over the last 7 years in one university hospital in Lebanon and compares our results to the international ones. Method: A single center retrospective study was done including all patients aged less than 15 years who underwent appendectomy. A description of each operative technique is presented. Patients' characteristics, intraoperative finding, operative timing (OT), length of stay (LOS) and short term postoperative complications including surgical site infection (SSI) rate, intra-abdominal abscess formation (IAA) rate and reoperation rate were all studied. Statistical analysis was done using Chi-square or Fisher's exact test, as for continuous, Student's t test was used or one-way ANOVA in case of more than 2 categories. Result: Appendectomy was performed in 84 patients. 52 patients underwent OA through a Rocky Davis incision, and 32 patients underwent a LA. We found an advantage of LA over OA in reducing SSI, otherwise both approaches were similar. Conclusion: In accordance with international results, in our experience, LA is superior to OA only with regards to SSI.","publication":"International Journal of Pediatrics and Adolescent Medicine","publication_with_fallback":"International Journal of Pediatrics and Adolescent Medicine","downloadable_attachments":[{"id":92342134,"asset_id":88353507,"asset_type":"Work","always_allow_download":false,"scribd_thumbnail_url":"https://attachments.academia-assets.com/92342134/thumbnails/1.jpg","download_url":"https://d1wqtxts1xzle7.cloudfront.net/92342134/ptpmcrender-libre.pdf?1665593751=\u0026response-content-disposition=attachment%3B+filename%3DPediatric_appendectomy_in_the_developing.pdf\u0026Expires=1733884396\u0026Signature=cdSQ6wmiF0XzYZaT4RCTuM8yLdmjTMhJT9Up9HGnO6ir2C0WJRrEycHBdy7jEEDbDXYzoKEjXvfIKmcxHMtmhmYHYTiqpThuMVc9UyNRVelMJ8CPTYg011LIshIQ8i7PW-NMJomiuYEyXMfbvbBFqw8XHkQZ4crUiKLheoN~1Zq22IgVZpHzyZjOxe6a9w-dde27aHs7fjy~wENE2U-xUE8DxN1aXy1CA08QGs~PtDw8WGTw~ie0UvA5U4z5zyBkTJ0KnC2WqPmxtwIquOFhlZn-zdATUBHnfV0vEIsg7in9vrg~sAI31UQjfVPX5TCzbd7Ke04CLBuxuVltfgvReA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA","download_file_url":"https://www.academia.edu/attachments/92342134/download_file?st=MTczMzk1ODAyOSw4LjIyMi4yMDguMTQ2&","full_thumbnail_url":"https://0.academia-photos.com/attachment_thumbnails/92342134/mini_magick20221012-1-1fjgzk0.png?1665593579"}],"downloadable_attachments_with_full_thumbnails":[{"id":92342134,"asset_id":88353507,"asset_type":"Work","always_allow_download":false,"scribd_thumbnail_url":"https://attachments.academia-assets.com/92342134/thumbnails/1.jpg","download_url":"https://d1wqtxts1xzle7.cloudfront.net/92342134/ptpmcrender-libre.pdf?1665593751=\u0026response-content-disposition=attachment%3B+filename%3DPediatric_appendectomy_in_the_developing.pdf\u0026Expires=1733884396\u0026Signature=cdSQ6wmiF0XzYZaT4RCTuM8yLdmjTMhJT9Up9HGnO6ir2C0WJRrEycHBdy7jEEDbDXYzoKEjXvfIKmcxHMtmhmYHYTiqpThuMVc9UyNRVelMJ8CPTYg011LIshIQ8i7PW-NMJomiuYEyXMfbvbBFqw8XHkQZ4crUiKLheoN~1Zq22IgVZpHzyZjOxe6a9w-dde27aHs7fjy~wENE2U-xUE8DxN1aXy1CA08QGs~PtDw8WGTw~ie0UvA5U4z5zyBkTJ0KnC2WqPmxtwIquOFhlZn-zdATUBHnfV0vEIsg7in9vrg~sAI31UQjfVPX5TCzbd7Ke04CLBuxuVltfgvReA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA","download_file_url":"https://www.academia.edu/attachments/92342134/download_file?st=MTczMzk1ODAyOSw4LjIyMi4yMDguMTQ2&","full_thumbnail_url":"https://0.academia-photos.com/attachment_thumbnails/92342134/mini_magick20221012-1-1fjgzk0.png?1665593579"}],"has_pdf":true,"has_fulltext":true,"page_count":4,"ordered_authors":[{"id":140393508,"first_name":"Nabil","last_name":"Diab","domain_name":"neu","page_name":"NabilDiab","display_name":"Nabil Diab","profile_url":"https://neu.academia.edu/NabilDiab","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine","nofollow":false},{"id":988280,"name":"Abscess","url":"https://www.academia.edu/Documents/in/Abscess","nofollow":false}],"publication_year":2019,"publication_year_with_fallback":2019,"paper_rank":null,"all_time_views":9,"active_discussion":{}}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_88353512" data-work_id="88353512" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/88353512/A_rare_cause_of_neonatal_intussusception_Considering_it_might_reduce_the_mortality_A_case_report_and_a_review_of_the_literature">A rare cause of neonatal intussusception. Considering it might reduce the mortality. A case report and a review of the literature</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Full-term neonatal intussusception is rare. Cecal duplication as a lead point for intussusception is very rare. We report a case of full-term neonate with ileo-cecal intussusception due to cecal duplication. Although cecal duplication... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_88353512" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Full-term neonatal intussusception is rare. Cecal duplication as a lead point for intussusception is very rare. We report a case of full-term neonate with ileo-cecal intussusception due to cecal duplication. Although cecal duplication represents rarely a surgical emergency, intussusception always needs immediate attention. The awareness of this entity is essential for diagnosis and management.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/88353512" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="19ec3d2c928dd66ce109c309ba8c6a44" rel="nofollow" data-download="{&quot;attachment_id&quot;:92342156,&quot;asset_id&quot;:88353512,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/92342156/download_file?st=MTczMzk1ODAyOSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="140393508" href="https://neu.academia.edu/NabilDiab">Nabil Diab</a><script data-card-contents-for-user="140393508" type="text/json">{"id":140393508,"first_name":"Nabil","last_name":"Diab","domain_name":"neu","page_name":"NabilDiab","display_name":"Nabil Diab","profile_url":"https://neu.academia.edu/NabilDiab","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_88353512 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="88353512"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 88353512, container: ".js-paper-rank-work_88353512", }); });</script></li><li class="js-percentile-work_88353512 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 88353512; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_88353512"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_88353512 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="88353512"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 88353512; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=88353512]").text(description); $(".js-view-count-work_88353512").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_88353512").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="88353512"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i></div><span class="InlineList-item-text u-textTruncate u-pl6x"><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a><script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine","nofollow":false}</script></span></li><script>(function(){ if (false) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=88353512]'), work: {"id":88353512,"title":"A rare cause of neonatal intussusception. Considering it might reduce the mortality. A case report and a review of the literature","created_at":"2022-10-12T09:51:02.997-07:00","owner_id":140393508,"url":"https://www.academia.edu/88353512/A_rare_cause_of_neonatal_intussusception_Considering_it_might_reduce_the_mortality_A_case_report_and_a_review_of_the_literature","slug":"A_rare_cause_of_neonatal_intussusception_Considering_it_might_reduce_the_mortality_A_case_report_and_a_review_of_the_literature","dom_id":"work_88353512","summary":"Full-term neonatal intussusception is rare. Cecal duplication as a lead point for intussusception is very rare. We report a case of full-term neonate with ileo-cecal intussusception due to cecal duplication. Although cecal duplication represents rarely a surgical emergency, intussusception always needs immediate attention. The awareness of this entity is essential for diagnosis and management.","publication":"International Journal of Pediatrics and Adolescent Medicine","publication_with_fallback":"International Journal of Pediatrics and Adolescent Medicine","downloadable_attachments":[{"id":92342156,"asset_id":88353512,"asset_type":"Work","always_allow_download":false,"scribd_thumbnail_url":"https://attachments.academia-assets.com/92342156/thumbnails/1.jpg","download_url":"https://d1wqtxts1xzle7.cloudfront.net/92342156/ptpmcrender-libre.pdf?1665593742=\u0026response-content-disposition=attachment%3B+filename%3DA_rare_cause_of_neonatal_intussusception.pdf\u0026Expires=1733961629\u0026Signature=FwQrfCRd04eEFmRzVhK4cE1HSY6IRyURPsLp2HFng6u6wVaX7Ec5u2DmhQdDxB72aHvhwbaFbQeVvSxwg-oTLqD4b5JYWoP5kfGYkjje0Yc9viZAPE0V1UbR7hVF-fXJStS8GC6hmV5dUAOVjdSp4I-RZxU81e92IpOZnSx-yPrVR1s-dxqZ~qSzhy3rXglmabCQjr1RjZ6dYezYNNEasikzlNkWx-eG6UCSl9NLVyec7VcdD4Pcaj4Sl8pt57ztNEoEsWYcXlTGPFIe16rjxOjdmz1KMtQmqlX5uaWfw5ElPjzZ06ZclwpH97xXc742Zl4S2BLjxzrn36UpWnKiiw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA","download_file_url":"https://www.academia.edu/attachments/92342156/download_file?st=MTczMzk1ODAyOSw4LjIyMi4yMDguMTQ2&","full_thumbnail_url":"https://0.academia-photos.com/attachment_thumbnails/92342156/mini_magick20221012-1-5ghn2d.png?1665593587"}],"downloadable_attachments_with_full_thumbnails":[{"id":92342156,"asset_id":88353512,"asset_type":"Work","always_allow_download":false,"scribd_thumbnail_url":"https://attachments.academia-assets.com/92342156/thumbnails/1.jpg","download_url":"https://d1wqtxts1xzle7.cloudfront.net/92342156/ptpmcrender-libre.pdf?1665593742=\u0026response-content-disposition=attachment%3B+filename%3DA_rare_cause_of_neonatal_intussusception.pdf\u0026Expires=1733961629\u0026Signature=FwQrfCRd04eEFmRzVhK4cE1HSY6IRyURPsLp2HFng6u6wVaX7Ec5u2DmhQdDxB72aHvhwbaFbQeVvSxwg-oTLqD4b5JYWoP5kfGYkjje0Yc9viZAPE0V1UbR7hVF-fXJStS8GC6hmV5dUAOVjdSp4I-RZxU81e92IpOZnSx-yPrVR1s-dxqZ~qSzhy3rXglmabCQjr1RjZ6dYezYNNEasikzlNkWx-eG6UCSl9NLVyec7VcdD4Pcaj4Sl8pt57ztNEoEsWYcXlTGPFIe16rjxOjdmz1KMtQmqlX5uaWfw5ElPjzZ06ZclwpH97xXc742Zl4S2BLjxzrn36UpWnKiiw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA","download_file_url":"https://www.academia.edu/attachments/92342156/download_file?st=MTczMzk1ODAyOSw4LjIyMi4yMDguMTQ2&","full_thumbnail_url":"https://0.academia-photos.com/attachment_thumbnails/92342156/mini_magick20221012-1-5ghn2d.png?1665593587"}],"has_pdf":true,"has_fulltext":true,"page_count":4,"ordered_authors":[{"id":140393508,"first_name":"Nabil","last_name":"Diab","domain_name":"neu","page_name":"NabilDiab","display_name":"Nabil Diab","profile_url":"https://neu.academia.edu/NabilDiab","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine","nofollow":false}],"publication_year":2019,"publication_year_with_fallback":2019,"paper_rank":null,"all_time_views":2,"active_discussion":{}}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_88353515" data-work_id="88353515" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/88353515/Retroperitoneoscopic_bilateral_nephrectomy_and_extraperitoneal_ureterocystoplasty_in_a_child_on_peritoneal_dialysis">Retroperitoneoscopic bilateral nephrectomy and extraperitoneal ureterocystoplasty in a child on peritoneal dialysis</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">A 4-year-old boy with posterior urethral valves and end stage kidney disease on peritoneal dialysis presented with high pressure non-compliant bladder with left ureterohydronephrosis. Inability to perform hemodialysis due to patient&#39;s... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_88353515" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">A 4-year-old boy with posterior urethral valves and end stage kidney disease on peritoneal dialysis presented with high pressure non-compliant bladder with left ureterohydronephrosis. Inability to perform hemodialysis due to patient&#39;s weight exclusion, imposed the necessity to preserve peritoneal dialysis. A bilateral nephrectomy by retroperitoneoscopy with extraperitoneal augmentation ureterocystoplasty using left ureter and pelvis associated with continent diversion using right ureter as umbilical stoma was performed followed by kidney transplantation. An excellent outcome with voluntary voiding without CIC is reported eighteen months later. This treatment modality is the best option to manage End Stage Kidney Disease on peritoneal dialysis in those patients.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/88353515" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="21656bfe29a8a7de5f7c3e09994da795" rel="nofollow" data-download="{&quot;attachment_id&quot;:92342140,&quot;asset_id&quot;:88353515,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/92342140/download_file?st=MTczMzk1ODAzMCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="140393508" href="https://neu.academia.edu/NabilDiab">Nabil Diab</a><script data-card-contents-for-user="140393508" type="text/json">{"id":140393508,"first_name":"Nabil","last_name":"Diab","domain_name":"neu","page_name":"NabilDiab","display_name":"Nabil Diab","profile_url":"https://neu.academia.edu/NabilDiab","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_88353515 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="88353515"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 88353515, container: ".js-paper-rank-work_88353515", }); });</script></li><li class="js-percentile-work_88353515 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 88353515; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_88353515"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_88353515 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="88353515"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 88353515; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=88353515]").text(description); $(".js-view-count-work_88353515").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_88353515").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="88353515"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">4</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="647" href="https://www.academia.edu/Documents/in/Surgery">Surgery</a>,&nbsp;<script data-card-contents-for-ri="647" type="text/json">{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>,&nbsp;<script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="447741" href="https://www.academia.edu/Documents/in/Peritoneal_Dialysis">Peritoneal Dialysis</a>,&nbsp;<script data-card-contents-for-ri="447741" type="text/json">{"id":447741,"name":"Peritoneal Dialysis","url":"https://www.academia.edu/Documents/in/Peritoneal_Dialysis","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="1190789" href="https://www.academia.edu/Documents/in/Nephrectomy">Nephrectomy</a><script data-card-contents-for-ri="1190789" type="text/json">{"id":1190789,"name":"Nephrectomy","url":"https://www.academia.edu/Documents/in/Nephrectomy","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=88353515]'), work: {"id":88353515,"title":"Retroperitoneoscopic bilateral nephrectomy and extraperitoneal ureterocystoplasty in a child on peritoneal dialysis","created_at":"2022-10-12T09:51:03.311-07:00","owner_id":140393508,"url":"https://www.academia.edu/88353515/Retroperitoneoscopic_bilateral_nephrectomy_and_extraperitoneal_ureterocystoplasty_in_a_child_on_peritoneal_dialysis","slug":"Retroperitoneoscopic_bilateral_nephrectomy_and_extraperitoneal_ureterocystoplasty_in_a_child_on_peritoneal_dialysis","dom_id":"work_88353515","summary":"A 4-year-old boy with posterior urethral valves and end stage kidney disease on peritoneal dialysis presented with high pressure non-compliant bladder with left ureterohydronephrosis. Inability to perform hemodialysis due to patient's weight exclusion, imposed the necessity to preserve peritoneal dialysis. A bilateral nephrectomy by retroperitoneoscopy with extraperitoneal augmentation ureterocystoplasty using left ureter and pelvis associated with continent diversion using right ureter as umbilical stoma was performed followed by kidney transplantation. An excellent outcome with voluntary voiding without CIC is reported eighteen months later. This treatment modality is the best option to manage End Stage Kidney Disease on peritoneal dialysis in those patients.","publication":"Urology Case Reports","publication_with_fallback":"Urology Case Reports","downloadable_attachments":[{"id":92342140,"asset_id":88353515,"asset_type":"Work","always_allow_download":false,"scribd_thumbnail_url":"https://attachments.academia-assets.com/92342140/thumbnails/1.jpg","download_url":"https://d1wqtxts1xzle7.cloudfront.net/92342140/j.eucr.2020.10119820221012-1-f74fs-libre.pdf?1665593749=\u0026response-content-disposition=attachment%3B+filename%3DRetroperitoneoscopic_bilateral_nephrecto.pdf\u0026Expires=1733961630\u0026Signature=DJfO4lgsA1G6WKbz6NAB69TnGaHjI-wL~58-6cI3htAP1kFR5y~ZXhLbbHc9E7GajYaiFey8ye-6xRdMOdaEaQS~npID-Gb0ozrGOL1ysTICMCnsSKuTs1nldoQ3UUcRFYHVwCX9fyBdb85XSgXuQKULZtb0h4DmrT0AAE3f4J5aPMIGDLBRad8XISRJIV5efC7DsHEPys1RYlzDsUuwuiC0UBkg8-uMA9HDYcSNoDI4nt5ZZDg3TaozODNdpSvP1FfRyJKCYACRpNHdkkQzpDKFTTw8teVdHZ2YjEqo0OHaoDHNp5qd0MEtX817HEhP0iByfvksX4Wl6GyBMcBuRg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA","download_file_url":"https://www.academia.edu/attachments/92342140/download_file?st=MTczMzk1ODAzMCw4LjIyMi4yMDguMTQ2&","full_thumbnail_url":"https://0.academia-photos.com/attachment_thumbnails/92342140/mini_magick20221012-1-15z8rfj.png?1665593585"}],"downloadable_attachments_with_full_thumbnails":[{"id":92342140,"asset_id":88353515,"asset_type":"Work","always_allow_download":false,"scribd_thumbnail_url":"https://attachments.academia-assets.com/92342140/thumbnails/1.jpg","download_url":"https://d1wqtxts1xzle7.cloudfront.net/92342140/j.eucr.2020.10119820221012-1-f74fs-libre.pdf?1665593749=\u0026response-content-disposition=attachment%3B+filename%3DRetroperitoneoscopic_bilateral_nephrecto.pdf\u0026Expires=1733961630\u0026Signature=DJfO4lgsA1G6WKbz6NAB69TnGaHjI-wL~58-6cI3htAP1kFR5y~ZXhLbbHc9E7GajYaiFey8ye-6xRdMOdaEaQS~npID-Gb0ozrGOL1ysTICMCnsSKuTs1nldoQ3UUcRFYHVwCX9fyBdb85XSgXuQKULZtb0h4DmrT0AAE3f4J5aPMIGDLBRad8XISRJIV5efC7DsHEPys1RYlzDsUuwuiC0UBkg8-uMA9HDYcSNoDI4nt5ZZDg3TaozODNdpSvP1FfRyJKCYACRpNHdkkQzpDKFTTw8teVdHZ2YjEqo0OHaoDHNp5qd0MEtX817HEhP0iByfvksX4Wl6GyBMcBuRg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA","download_file_url":"https://www.academia.edu/attachments/92342140/download_file?st=MTczMzk1ODAzMCw4LjIyMi4yMDguMTQ2&","full_thumbnail_url":"https://0.academia-photos.com/attachment_thumbnails/92342140/mini_magick20221012-1-15z8rfj.png?1665593585"}],"has_pdf":true,"has_fulltext":true,"page_count":3,"ordered_authors":[{"id":140393508,"first_name":"Nabil","last_name":"Diab","domain_name":"neu","page_name":"NabilDiab","display_name":"Nabil Diab","profile_url":"https://neu.academia.edu/NabilDiab","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine","nofollow":false},{"id":447741,"name":"Peritoneal Dialysis","url":"https://www.academia.edu/Documents/in/Peritoneal_Dialysis","nofollow":false},{"id":1190789,"name":"Nephrectomy","url":"https://www.academia.edu/Documents/in/Nephrectomy","nofollow":false}],"publication_year":2020,"publication_year_with_fallback":2020,"paper_rank":null,"all_time_views":4,"active_discussion":{}}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_88353521" data-work_id="88353521" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/88353521/Another_indication_for_a_transanal_pull_through_surgical_management_of_rectal_atresia_a_case_report">Another indication for a transanal pull-through: surgical management of rectal atresia—a case report</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Background Rectal atresia is a very rare cause of neonatal intestinal obstruction. It has some distinctive anatomical and physiological specifications. The management is controversial with many described operative techniques. In this case... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_88353521" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Background Rectal atresia is a very rare cause of neonatal intestinal obstruction. It has some distinctive anatomical and physiological specifications. The management is controversial with many described operative techniques. In this case report, we described our patient that we operated according to the transanal pull-through technique. We discussed the advantages and disadvantages of this technique and what makes it a suitable option for this population of patient. Case presentation A full-term male patient presented at 36 h of life for a pneumoperitoneum. Because of his well-placed, normally appearing anus, the diagnosis of rectal atresia was delayed. The patient was operated then according to the transanal pull-through technique with good follow-up results. Conclusion Transanal pull-through is a safe, easy. and a potentially reproducible option for managing rectal atresia. It should be considered for managing future cases. More cases should be done before drawing big conclusions.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/88353521" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="49f1d8bcfe1acaf487b003a0ee0e73f4" rel="nofollow" data-download="{&quot;attachment_id&quot;:92342101,&quot;asset_id&quot;:88353521,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/92342101/download_file?st=MTczMzk1ODAzMCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="140393508" href="https://neu.academia.edu/NabilDiab">Nabil Diab</a><script data-card-contents-for-user="140393508" type="text/json">{"id":140393508,"first_name":"Nabil","last_name":"Diab","domain_name":"neu","page_name":"NabilDiab","display_name":"Nabil Diab","profile_url":"https://neu.academia.edu/NabilDiab","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_88353521 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="88353521"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 88353521, container: ".js-paper-rank-work_88353521", }); 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It has some distinctive anatomical and physiological specifications. The management is controversial with many described operative techniques. In this case report, we described our patient that we operated according to the transanal pull-through technique. We discussed the advantages and disadvantages of this technique and what makes it a suitable option for this population of patient. Case presentation A full-term male patient presented at 36 h of life for a pneumoperitoneum. Because of his well-placed, normally appearing anus, the diagnosis of rectal atresia was delayed. The patient was operated then according to the transanal pull-through technique with good follow-up results. Conclusion Transanal pull-through is a safe, easy. and a potentially reproducible option for managing rectal atresia. It should be considered for managing future cases. More cases should be done before drawing big conclusions.","publication":"Annals of Pediatric Surgery","publication_with_fallback":"Annals of Pediatric Surgery","downloadable_attachments":[{"id":92342101,"asset_id":88353521,"asset_type":"Work","always_allow_download":false,"scribd_thumbnail_url":"https://attachments.academia-assets.com/92342101/thumbnails/1.jpg","download_url":"https://d1wqtxts1xzle7.cloudfront.net/92342101/s43159-021-00143-2-libre.pdf?1665593824=\u0026response-content-disposition=attachment%3B+filename%3DAnother_indication_for_a_transanal_pull.pdf\u0026Expires=1733961630\u0026Signature=UbfY9~cYY8rkemru4mVJ3Uz9UJzY1hX4pChyR8q5M0olcijrX7SgQp7NuR0TAuVuE8RaQcQ-YKwlz9wV7zjGPwsPCAbmkYgpUSaAX6T~m~QFIxy94KDSrBAEclVClUQU~ZCh-7T46z5y3NFmC8W6gFfjIXU9ZKZKwSkfi~e1EJSVqO9cbdU5bU2fdMjs-sQJgjtoixj48MyO~QiyHIj1-bu9IyXT1DmL1SwmxoaA4aEIFNxL6D6aBY1cDiG2K18u4dVzB5LHhOmNEUkKdA1DomNxi2c~u03yrSpYBW596xEnRzEahdCWaT2Yi-g03LSvYkNRbZA9Xs5IqR4G~x39cg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA","download_file_url":"https://www.academia.edu/attachments/92342101/download_file?st=MTczMzk1ODAzMCw4LjIyMi4yMDguMTQ2&","full_thumbnail_url":"https://0.academia-photos.com/attachment_thumbnails/92342101/mini_magick20221012-1-15xxkqu.png?1665593514"}],"downloadable_attachments_with_full_thumbnails":[{"id":92342101,"asset_id":88353521,"asset_type":"Work","always_allow_download":false,"scribd_thumbnail_url":"https://attachments.academia-assets.com/92342101/thumbnails/1.jpg","download_url":"https://d1wqtxts1xzle7.cloudfront.net/92342101/s43159-021-00143-2-libre.pdf?1665593824=\u0026response-content-disposition=attachment%3B+filename%3DAnother_indication_for_a_transanal_pull.pdf\u0026Expires=1733961630\u0026Signature=UbfY9~cYY8rkemru4mVJ3Uz9UJzY1hX4pChyR8q5M0olcijrX7SgQp7NuR0TAuVuE8RaQcQ-YKwlz9wV7zjGPwsPCAbmkYgpUSaAX6T~m~QFIxy94KDSrBAEclVClUQU~ZCh-7T46z5y3NFmC8W6gFfjIXU9ZKZKwSkfi~e1EJSVqO9cbdU5bU2fdMjs-sQJgjtoixj48MyO~QiyHIj1-bu9IyXT1DmL1SwmxoaA4aEIFNxL6D6aBY1cDiG2K18u4dVzB5LHhOmNEUkKdA1DomNxi2c~u03yrSpYBW596xEnRzEahdCWaT2Yi-g03LSvYkNRbZA9Xs5IqR4G~x39cg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA","download_file_url":"https://www.academia.edu/attachments/92342101/download_file?st=MTczMzk1ODAzMCw4LjIyMi4yMDguMTQ2&","full_thumbnail_url":"https://0.academia-photos.com/attachment_thumbnails/92342101/mini_magick20221012-1-15xxkqu.png?1665593514"}],"has_pdf":true,"has_fulltext":true,"page_count":4,"ordered_authors":[{"id":140393508,"first_name":"Nabil","last_name":"Diab","domain_name":"neu","page_name":"NabilDiab","display_name":"Nabil Diab","profile_url":"https://neu.academia.edu/NabilDiab","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine","nofollow":false}],"publication_year":2022,"publication_year_with_fallback":2022,"paper_rank":null,"all_time_views":3,"active_discussion":{}}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_93791521" data-work_id="93791521" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/93791521/Glomerular_disease_during_HCV_infection_in_renal_transplantation">Glomerular disease during HCV infection in renal transplantation</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">In general nephrology, HCV infection has been associated with type I membranoproliferative glomerulonephritis (MPGN type I) associated with cryoglobulinaemia. In a cohort of 399 renal transplantation (RT) recipients, 117 of whom (29%)... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_93791521" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">In general nephrology, HCV infection has been associated with type I membranoproliferative glomerulonephritis (MPGN type I) associated with cryoglobulinaemia. In a cohort of 399 renal transplantation (RT) recipients, 117 of whom (29%) were HCV-positive, we selected all patients diagnosed as having membranous GN or type I MPGN by graft biopsy. The prevalence of MGN was 16/399 (4%) with three recurrences, and 13 de novo cases. Only 5/16 (31%) were HCV+, not different from the general RT population. Five patients had an outcome of graft failure after 43 months. Conversely, there were 15 cases of type I MPGN (two recurrences, 13 de novo) but with eight HCV+ recipients (53%, P=0.02). Considering only the French patients, prevalence was 44% vs 12% in the French RT population (P=0.006). Eight patients had graft rejection after 59 months (five HCV+). In this type I MPGN subgroup, there were two positive cryoglobulins, two rheumatoid factors and four hypocomplementaemias. In conclusion, there is a clear association between HCV infection and the occurrence of type I MPGN hi the allograft hi renal transplantation, with terminal renal failure as an outcome.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/93791521" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="898fad567f5616d9566708ccc7a6d547" rel="nofollow" data-download="{&quot;attachment_id&quot;:96431699,&quot;asset_id&quot;:93791521,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/96431699/download_file?st=MTczMzk1ODAzMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="140393508" href="https://neu.academia.edu/NabilDiab">Nabil Diab</a><script data-card-contents-for-user="140393508" type="text/json">{"id":140393508,"first_name":"Nabil","last_name":"Diab","domain_name":"neu","page_name":"NabilDiab","display_name":"Nabil Diab","profile_url":"https://neu.academia.edu/NabilDiab","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_93791521 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="93791521"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 93791521, container: ".js-paper-rank-work_93791521", }); 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$(".js-view-count[data-work-id=93791521]").text(description); $(".js-view-count-work_93791521").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_93791521").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="93791521"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">15</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="622" href="https://www.academia.edu/Documents/in/Nephrology">Nephrology</a>,&nbsp;<script data-card-contents-for-ri="622" type="text/json">{"id":622,"name":"Nephrology","url":"https://www.academia.edu/Documents/in/Nephrology","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="3274" href="https://www.academia.edu/Documents/in/Gastroenterology">Gastroenterology</a>,&nbsp;<script data-card-contents-for-ri="3274" type="text/json">{"id":3274,"name":"Gastroenterology","url":"https://www.academia.edu/Documents/in/Gastroenterology","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="9003" href="https://www.academia.edu/Documents/in/Kidney_transplantation">Kidney transplantation</a>,&nbsp;<script data-card-contents-for-ri="9003" type="text/json">{"id":9003,"name":"Kidney transplantation","url":"https://www.academia.edu/Documents/in/Kidney_transplantation","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a><script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=93791521]'), work: {"id":93791521,"title":"Glomerular disease during HCV infection in renal transplantation","created_at":"2022-12-27T07:10:44.737-08:00","owner_id":140393508,"url":"https://www.academia.edu/93791521/Glomerular_disease_during_HCV_infection_in_renal_transplantation","slug":"Glomerular_disease_during_HCV_infection_in_renal_transplantation","dom_id":"work_93791521","summary":"In general nephrology, HCV infection has been associated with type I membranoproliferative glomerulonephritis (MPGN type I) associated with cryoglobulinaemia. In a cohort of 399 renal transplantation (RT) recipients, 117 of whom (29%) were HCV-positive, we selected all patients diagnosed as having membranous GN or type I MPGN by graft biopsy. The prevalence of MGN was 16/399 (4%) with three recurrences, and 13 de novo cases. Only 5/16 (31%) were HCV+, not different from the general RT population. Five patients had an outcome of graft failure after 43 months. Conversely, there were 15 cases of type I MPGN (two recurrences, 13 de novo) but with eight HCV+ recipients (53%, P=0.02). Considering only the French patients, prevalence was 44% vs 12% in the French RT population (P=0.006). Eight patients had graft rejection after 59 months (five HCV+). In this type I MPGN subgroup, there were two positive cryoglobulins, two rheumatoid factors and four hypocomplementaemias. In conclusion, there is a clear association between HCV infection and the occurrence of type I MPGN hi the allograft hi renal transplantation, with terminal renal failure as an outcome.","publication":"Nephrology Dialysis Transplantation","publication_with_fallback":"Nephrology Dialysis Transplantation","downloadable_attachments":[{"id":96431699,"asset_id":93791521,"asset_type":"Work","always_allow_download":false,"scribd_thumbnail_url":"https://attachments.academia-assets.com/96431699/thumbnails/1.jpg","download_url":"https://d1wqtxts1xzle7.cloudfront.net/96431699/11-supp4-54-libre.pdf?1672156983=\u0026response-content-disposition=attachment%3B+filename%3DGlomerular_disease_during_HCV_infection.pdf\u0026Expires=1733961630\u0026Signature=Lhjx~bts1~skpUceWyKMq2I80sVxHsD~QsV1Kya6FyzFTGJ1pT2oCFhvILB-rHPRI4APtAb28QdUHi9V4ySVxAPkiSkB2KSTmWlXz3TQ9z0aCKfDrBV9Lnyvp-OJaesvBcjnaXz4zB55tn1PRNM8ilGgy5p53EAxDl0lN4B7AHwOHF2~4Pg7DoZ2V9KiJLII0LE0AgSUR-52lxPFXSOsQMxk3NxnQ1J7lcZMCYa9~Wq6HEO4FD9geqR-idv7PnHpHlV12NJjHycQ3EQOPZd9ydMDrXTrmTdbzOdAt344F50laO4q6kulz0VzMNYltfbyokxBVY~gzlk45Be9fYrf7g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA","download_file_url":"https://www.academia.edu/attachments/96431699/download_file?st=MTczMzk1ODAzMSw4LjIyMi4yMDguMTQ2&","full_thumbnail_url":"https://0.academia-photos.com/attachment_thumbnails/96431699/mini_magick20221227-1-ow3svb.png?1672154149"}],"downloadable_attachments_with_full_thumbnails":[{"id":96431699,"asset_id":93791521,"asset_type":"Work","always_allow_download":false,"scribd_thumbnail_url":"https://attachments.academia-assets.com/96431699/thumbnails/1.jpg","download_url":"https://d1wqtxts1xzle7.cloudfront.net/96431699/11-supp4-54-libre.pdf?1672156983=\u0026response-content-disposition=attachment%3B+filename%3DGlomerular_disease_during_HCV_infection.pdf\u0026Expires=1733961631\u0026Signature=agOg1eZw0QExcUEY-QLjjpLoin~BTrXI3s3PV9b0P3xeJuL7GA6y5Vf0EcwZATJdPr6tY5jSfNPyE0C~LDjuA4dL3~dsJzmq1gUG5nDfhq54Q8q1sxrLVHZMJVRaLPjGB2y3lIfFnxfehS5~6xmBKKecZvNKu~9W866HUM6MbpvpPIht6Wz81SIO5yXEdp5G7iLtCw~eq2xHUlt6W0AeQtECxhJA4Hv4I2bEBl~N8DEu4olFC8VQGw-0yriMluyjibwxqcScB45R7vlcJ2NThW3hAdeNcNyrs6rw1858DxIVOcqzp1KkVSQgvfFyw1~DWf4xbZ49A7qP3z3nllhL7g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA","download_file_url":"https://www.academia.edu/attachments/96431699/download_file?st=MTczMzk1ODAzMSw4LjIyMi4yMDguMTQ2&","full_thumbnail_url":"https://0.academia-photos.com/attachment_thumbnails/96431699/mini_magick20221227-1-ow3svb.png?1672154149"}],"has_pdf":true,"has_fulltext":true,"page_count":2,"ordered_authors":[{"id":140393508,"first_name":"Nabil","last_name":"Diab","domain_name":"neu","page_name":"NabilDiab","display_name":"Nabil 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data-work_id="93791524" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/93791524/New_subgroup_of_primary_IgA_nephritis_with_thin_glomerular_basement_membrane_GBM_syndrome_or_association">New subgroup of primary IgA nephritis with thin glomerular basement membrane (GBM): syndrome or association</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">IMephrology Dialysis Transplantation New subgroup of primary IgA nephritis with thin glomerular basement membrane (GBM): syndrome or association</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/93791524" data-share-source="work_strip" 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class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="140393508" href="https://neu.academia.edu/NabilDiab">Nabil Diab</a><script data-card-contents-for-user="140393508" type="text/json">{"id":140393508,"first_name":"Nabil","last_name":"Diab","domain_name":"neu","page_name":"NabilDiab","display_name":"Nabil Diab","profile_url":"https://neu.academia.edu/NabilDiab","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_93791524 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="93791524"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 93791524, container: ".js-paper-rank-work_93791524", }); });</script></li><li class="js-percentile-work_93791524 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 93791524; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_93791524"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_93791524 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="93791524"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 93791524; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=93791524]").text(description); $(".js-view-count-work_93791524").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_93791524").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="93791524"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">5</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>,&nbsp;<script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="71436" href="https://www.academia.edu/Documents/in/Basement_Membrane">Basement Membrane</a>,&nbsp;<script data-card-contents-for-ri="71436" type="text/json">{"id":71436,"name":"Basement Membrane","url":"https://www.academia.edu/Documents/in/Basement_Membrane","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a>,&nbsp;<script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="1225171" href="https://www.academia.edu/Documents/in/Syndrome">Syndrome</a><script data-card-contents-for-ri="1225171" 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itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/104085942/Congenital_Prepubic_Sinus">Congenital Prepubic Sinus</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Congenital prepubic sinus is a rare anomaly: only five pediatric cases have to our knowledge been reported to date. We report two further cases with the sinus extending from the overlying skin through the rectus fascia to the anterior... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_104085942" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Congenital prepubic sinus is a rare anomaly: only five pediatric cases have to our knowledge been reported to date. We report two further cases with the sinus extending from the overlying skin through the rectus fascia to the anterior bladder wall. In our first case the opening of the sinus was just 3 cm below the midline inferior to the navel, with concentric, thin smoothmuscle layers. This lesion may represent a mild forme fruste of a midline closure defect. In our second case, the sinus was lined by transitional epithelium in its distal portion with stratified squamous epithelium near the surface, and was also surrounded by a thin smooth-muscle layer. These two cases may represent a variant of epispadiac urethral duplication. Our observations suggest that congenital prepubic sinus and urethral duplication are related embryologically.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/104085942" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="ac82827d61086ce8cd783fca2fefbdb9" rel="nofollow" data-download="{&quot;attachment_id&quot;:103906964,&quot;asset_id&quot;:104085942,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/103906964/download_file?st=MTczMzk1ODAzMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="140393508" href="https://neu.academia.edu/NabilDiab">Nabil Diab</a><script data-card-contents-for-user="140393508" type="text/json">{"id":140393508,"first_name":"Nabil","last_name":"Diab","domain_name":"neu","page_name":"NabilDiab","display_name":"Nabil Diab","profile_url":"https://neu.academia.edu/NabilDiab","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_104085942 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="104085942"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 104085942, container: ".js-paper-rank-work_104085942", }); 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$(".js-view-count[data-work-id=104085942]").text(description); $(".js-view-count-work_104085942").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_104085942").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="104085942"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">4</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>,&nbsp;<script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="134346" href="https://www.academia.edu/Documents/in/Infant">Infant</a>,&nbsp;<script data-card-contents-for-ri="134346" type="text/json">{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="1561359" href="https://www.academia.edu/Documents/in/Pubic_Symphysis">Pubic Symphysis</a>,&nbsp;<script data-card-contents-for-ri="1561359" type="text/json">{"id":1561359,"name":"Pubic Symphysis","url":"https://www.academia.edu/Documents/in/Pubic_Symphysis","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="3789883" href="https://www.academia.edu/Documents/in/Paediatrics_and_reproductive_medicine">Paediatrics and reproductive medicine</a><script data-card-contents-for-ri="3789883" type="text/json">{"id":3789883,"name":"Paediatrics and reproductive medicine","url":"https://www.academia.edu/Documents/in/Paediatrics_and_reproductive_medicine","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=104085942]'), work: {"id":104085942,"title":"Congenital Prepubic Sinus","created_at":"2023-06-30T08:47:53.250-07:00","owner_id":140393508,"url":"https://www.academia.edu/104085942/Congenital_Prepubic_Sinus","slug":"Congenital_Prepubic_Sinus","dom_id":"work_104085942","summary":"Congenital prepubic sinus is a rare anomaly: only five pediatric cases have to our knowledge been reported to date. We report two further cases with the sinus extending from the overlying skin through the rectus fascia to the anterior bladder wall. In our first case the opening of the sinus was just 3 cm below the midline inferior to the navel, with concentric, thin smoothmuscle layers. This lesion may represent a mild forme fruste of a midline closure defect. In our second case, the sinus was lined by transitional epithelium in its distal portion with stratified squamous epithelium near the surface, and was also surrounded by a thin smooth-muscle layer. These two cases may represent a variant of epispadiac urethral duplication. Our observations suggest that congenital prepubic sinus and urethral duplication are related embryologically.","publication":"European Journal of Pediatric Surgery","publication_with_fallback":"European Journal of Pediatric Surgery","downloadable_attachments":[{"id":103906964,"asset_id":104085942,"asset_type":"Work","always_allow_download":false,"scribd_thumbnail_url":"https://attachments.academia-assets.com/103906964/thumbnails/1.jpg","download_url":"https://d1wqtxts1xzle7.cloudfront.net/103906964/bf0083226020230630-1-smcyhn-libre.pdf?1688140206=\u0026response-content-disposition=attachment%3B+filename%3DCongenital_Prepubic_Sinus.pdf\u0026Expires=1733961631\u0026Signature=QaOee5UiwkNe4x5L5omWRrwwy4Ar~uRBjKE1A-CFbfHYpI~jq83nKcoT9GbINJh3Jh4h9lidwseGt8~YDqoaeYmYQ6LvBKGjEVYS3PPtuD5GvtENoCKl1CILQJbzB8AMhByvZh-w2BZAJWZX2kG8ROUFCaW9fveQB8eQ038TPqylXo0v-q7eDJR7wTc3GhoNgq4Q8Vx4uGK3kcoXLFFG3nSFXCAurcUKcI3rAffVeUXyIT1RknQq9R8Op~QueB9B~myxA7xKwiw4VrK4xb6ODe3Xnj9Nl8KLY5Ws998AJGB1B44h3gH59nY5nKTm89ptusnUGGBECVqLBaA266660A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA","download_file_url":"https://www.academia.edu/attachments/103906964/download_file?st=MTczMzk1ODAzMSw4LjIyMi4yMDguMTQ2&","full_thumbnail_url":"https://0.academia-photos.com/attachment_thumbnails/103906964/mini_magick20230630-1-mysx6w.png?1688169217"}],"downloadable_attachments_with_full_thumbnails":[{"id":103906964,"asset_id":104085942,"asset_type":"Work","always_allow_download":false,"scribd_thumbnail_url":"https://attachments.academia-assets.com/103906964/thumbnails/1.jpg","download_url":"https://d1wqtxts1xzle7.cloudfront.net/103906964/bf0083226020230630-1-smcyhn-libre.pdf?1688140206=\u0026response-content-disposition=attachment%3B+filename%3DCongenital_Prepubic_Sinus.pdf\u0026Expires=1733961631\u0026Signature=QaOee5UiwkNe4x5L5omWRrwwy4Ar~uRBjKE1A-CFbfHYpI~jq83nKcoT9GbINJh3Jh4h9lidwseGt8~YDqoaeYmYQ6LvBKGjEVYS3PPtuD5GvtENoCKl1CILQJbzB8AMhByvZh-w2BZAJWZX2kG8ROUFCaW9fveQB8eQ038TPqylXo0v-q7eDJR7wTc3GhoNgq4Q8Vx4uGK3kcoXLFFG3nSFXCAurcUKcI3rAffVeUXyIT1RknQq9R8Op~QueB9B~myxA7xKwiw4VrK4xb6ODe3Xnj9Nl8KLY5Ws998AJGB1B44h3gH59nY5nKTm89ptusnUGGBECVqLBaA266660A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA","download_file_url":"https://www.academia.edu/attachments/103906964/download_file?st=MTczMzk1ODAzMSw4LjIyMi4yMDguMTQ2&","full_thumbnail_url":"https://0.academia-photos.com/attachment_thumbnails/103906964/mini_magick20230630-1-mysx6w.png?1688169217"}],"has_pdf":true,"has_fulltext":true,"page_count":3,"ordered_authors":[{"id":140393508,"first_name":"Nabil","last_name":"Diab","domain_name":"neu","page_name":"NabilDiab","display_name":"Nabil 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