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Newborns are at a higher risk of severe disease including meningoencephalitis, sepsis syndrome, cardiovascular collapse, or hepatitis. The mechanism of heart failure in patients with" /> <meta name="twitter:image" content="https://0.academia-photos.com/299233122/144927489/134455583/s200_lidija.banjac.png" /> <meta property="fb:app_id" content="2369844204" /> <meta property="og:type" content="article" /> <meta property="og:url" content="https://www.academia.edu/116988777/Tachycardia_in_a_newborn_with_enterovirus_infection" /> <meta property="og:title" content="Tachycardia in a newborn with enterovirus infection" /> <meta property="og:image" content="http://a.academia-assets.com/images/open-graph-icons/fb-paper.gif" /> <meta property="og:description" content="Enterovirus infections are common in the neonatal period. Newborns are at a higher risk of severe disease including meningoencephalitis, sepsis syndrome, cardiovascular collapse, or hepatitis. The mechanism of heart failure in patients with" /> <meta property="article:author" content="https://independent.academia.edu/BanjacLidija" /> <meta name="description" content="Enterovirus infections are common in the neonatal period. Newborns are at a higher risk of severe disease including meningoencephalitis, sepsis syndrome, cardiovascular collapse, or hepatitis. The mechanism of heart failure in patients with" /> <title>(PDF) Tachycardia in a newborn with enterovirus infection | Lidija Banjac - Academia.edu</title> <link rel="canonical" href="https://www.academia.edu/116988777/Tachycardia_in_a_newborn_with_enterovirus_infection" /> <script async src="https://www.googletagmanager.com/gtag/js?id=G-5VKX33P2DS"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-5VKX33P2DS', { cookie_domain: 'academia.edu', send_page_view: false, }); gtag('event', 'page_view', { 'controller': "single_work", 'action': "show", 'controller_action': 'single_work#show', 'logged_in': 'false', 'edge': 'unknown', // Send nil if there is no A/B test bucket, in case some records get logged // with missing data - that way we can distinguish between the two cases. // ab_test_bucket should be of the form <ab_test_name>:<bucket> 'ab_test_bucket': null, }) </script> <script> var $controller_name = 'single_work'; var $action_name = "show"; var $rails_env = 'production'; var $app_rev = '49879c2402910372f4abc62630a427bbe033d190'; var $domain = 'academia.edu'; var $app_host = "academia.edu"; var $asset_host = "academia-assets.com"; var $start_time = new Date().getTime(); var $recaptcha_key = "6LdxlRMTAAAAADnu_zyLhLg0YF9uACwz78shpjJB"; var $recaptcha_invisible_key = "6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj"; var $disableClientRecordHit = false; </script> <script> window.require = { config: function() { return function() {} } } </script> <script> window.Aedu = window.Aedu || {}; window.Aedu.hit_data = null; window.Aedu.serverRenderTime = new Date(1732473694000); window.Aedu.timeDifference = new Date().getTime() - 1732473694000; </script> <script type="application/ld+json">{"@context":"https://schema.org","@type":"ScholarlyArticle","abstract":"Enterovirus infections are common in the neonatal period. Newborns are at a higher risk of severe disease including meningoencephalitis, sepsis syndrome, cardiovascular collapse, or hepatitis. The mechanism of heart failure in patients with enterovirus infection remains unknown. Early diagnosis may help clinicians predict complications in those infants initially presenting with severe disease. An 11-day-old male newborn was admitted to our neonatal intensive care unit because of tachycardia and crises of cyanosis. His elder brother had febrile illness. The newborn was cyanotic, in respiratory distress, with tachycardia, low blood pressure and prolonged capillary refilling time. Limb pulse oximeter was around 85%. During the first day of hospitalization, the newborn had one febrile episode. Laboratory data: elevated transaminases, markers of inflammation negative, all bacterial cultures negative. Enterovirus RNA was detected in blood sample. Other blood findings were without signific...","author":[{"@context":"https://schema.org","@type":"Person","name":"Lidija Banjac"}],"contributor":[],"dateCreated":"2024-04-02","dateModified":null,"datePublished":"2014-01-01","headline":"Tachycardia in a newborn with enterovirus infection","inLanguage":"en","keywords":["Medicine","Humans","Montenegro","Pubmed","Male","Myocarditis","Clinical Sciences","Newborn Infant","Tachycardia","Enterovirus","Podgorica"],"locationCreated":null,"publication":"Acta clinica Croatica","publisher":{"@context":"https://schema.org","@type":"Organization","name":null},"image":null,"thumbnailUrl":null,"url":"https://www.academia.edu/116988777/Tachycardia_in_a_newborn_with_enterovirus_infection","sourceOrganization":[{"@context":"https://schema.org","@type":"EducationalOrganization","name":null}]}</script><link rel="stylesheet" media="all" 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"https://www.academia.edu/login?post_login_redirect_url=https%3A%2F%2Fwww.academia.edu%2F116988777%2FTachycardia_in_a_newborn_with_enterovirus_infection%3Fauto%3Ddownload"; window.loswp.translateUrl = "https://www.academia.edu/login?post_login_redirect_url=https%3A%2F%2Fwww.academia.edu%2F116988777%2FTachycardia_in_a_newborn_with_enterovirus_infection%3Fshow_translation%3Dtrue"; window.loswp.previewableAttachments = [{"id":112966821,"identifier":"Attachment_112966821","shouldShowBulkDownload":false}]; window.loswp.shouldDetectTimezone = true; window.loswp.shouldShowBulkDownload = true; window.loswp.showSignupCaptcha = false window.loswp.willEdgeCache = false; window.loswp.work = {"work":{"id":116988777,"created_at":"2024-04-02T09:45:54.617-07:00","from_world_paper_id":252318657,"updated_at":"2024-04-19T20:57:04.327-07:00","_data":{"abstract":"Enterovirus infections are common in the neonatal period. Newborns are at a higher risk of severe disease including meningoencephalitis, sepsis syndrome, cardiovascular collapse, or hepatitis. The mechanism of heart failure in patients with enterovirus infection remains unknown. Early diagnosis may help clinicians predict complications in those infants initially presenting with severe disease. An 11-day-old male newborn was admitted to our neonatal intensive care unit because of tachycardia and crises of cyanosis. His elder brother had febrile illness. The newborn was cyanotic, in respiratory distress, with tachycardia, low blood pressure and prolonged capillary refilling time. Limb pulse oximeter was around 85%. During the first day of hospitalization, the newborn had one febrile episode. Laboratory data: elevated transaminases, markers of inflammation negative, all bacterial cultures negative. Enterovirus RNA was detected in blood sample. Other blood findings were without signific...","publication_date":"2014,,","publication_name":"Acta clinica Croatica"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Tachycardia in a newborn with enterovirus infection","broadcastable":true,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [299233122]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container js-loswp-work-card"><div class="ds-work-card--cover"><div class="ds-work-cover--wrapper"><div class="ds-work-cover--container"><button class="ds-work-cover--clickable js-swp-download-button" data-signup-modal="{"location":"swp-splash-paper-cover","attachmentId":112966821,"attachmentType":"pdf"}"><img alt="First page of “Tachycardia in a newborn with enterovirus infection”" class="ds-work-cover--cover-thumbnail" src="https://0.academia-photos.com/attachment_thumbnails/112966821/mini_magick20240802-1-tlh2pa.png?1722631921" /><img alt="PDF Icon" class="ds-work-cover--file-icon" src="//a.academia-assets.com/assets/single_work_splash/adobe.icon-574afd46eb6b03a77a153a647fb47e30546f9215c0ee6a25df597a779717f9ef.svg" /><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Tachycardia in a newborn with enterovirus infection</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="299233122" href="https://independent.academia.edu/BanjacLidija"><img alt="Profile image of Lidija Banjac" class="ds-work-card--author-avatar" src="https://0.academia-photos.com/299233122/144927489/134455583/s65_lidija.banjac.png" />Lidija Banjac</a></div><p class="ds-work-card--detail ds2-5-body-sm">2014, Acta clinica Croatica</p><p class="ds-work-card--work-abstract ds-work-card--detail ds2-5-body-md">Enterovirus infections are common in the neonatal period. Newborns are at a higher risk of severe disease including meningoencephalitis, sepsis syndrome, cardiovascular collapse, or hepatitis. The mechanism of heart failure in patients with enterovirus infection remains unknown. Early diagnosis may help clinicians predict complications in those infants initially presenting with severe disease. An 11-day-old male newborn was admitted to our neonatal intensive care unit because of tachycardia and crises of cyanosis. His elder brother had febrile illness. The newborn was cyanotic, in respiratory distress, with tachycardia, low blood pressure and prolonged capillary refilling time. Limb pulse oximeter was around 85%. During the first day of hospitalization, the newborn had one febrile episode. Laboratory data: elevated transaminases, markers of inflammation negative, all bacterial cultures negative. Enterovirus RNA was detected in blood sample. Other blood findings were without signific...</p><div class="ds-work-card--button-container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--work-card","attachmentId":112966821,"attachmentType":"pdf","workUrl":"https://www.academia.edu/116988777/Tachycardia_in_a_newborn_with_enterovirus_infection"}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--work-card","attachmentId":112966821,"attachmentType":"pdf","workUrl":"https://www.academia.edu/116988777/Tachycardia_in_a_newborn_with_enterovirus_infection"}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div></div><div data-auto_select="false" data-client_id="331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b" data-doc_id="112966821" data-landing_url="https://www.academia.edu/116988777/Tachycardia_in_a_newborn_with_enterovirus_infection" data-login_uri="https://www.academia.edu/registrations/google_one_tap" data-moment_callback="onGoogleOneTapEvent" id="g_id_onload"></div><div class="ds-top-related-works--grid-container"><div class="ds-related-content--container ds-top-related-works--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="0" data-entity-id="52829753" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/52829753/Neonatal_Enterovirus_Infection_Case_Series_of_Clinical_Sepsis_and_Positive_Cerebrospinal_Fluid_Polymerase_Chain_Reaction_Test_with_Myocarditis_and_Cerebral_White_Matter_Injury_Complications">Neonatal Enterovirus Infection: Case Series of Clinical Sepsis and Positive Cerebrospinal Fluid Polymerase Chain Reaction Test with Myocarditis and Cerebral White Matter Injury Complications</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="39179792" href="https://independent.academia.edu/FrankMorriss">Frank Morriss</a></div><p class="ds-related-work--metadata ds2-5-body-xs">AJP reports, 2016</p><p class="ds-related-work--abstract ds2-5-body-sm">Objective We describe five neonates with enteroviral (EV) infection to demonstrate central nervous system (CNS) and cardiac complications and report successful treatment of myocarditis with immunoglobulin intravenous (IVIG) in two. Study Design Case series identified during three enteroviral seasons in one neonatal intensive care unit (NICU) by cerebral spinal fluid (CSF) reverse transcriptase polymerase chain reaction (PCR) testing for EV in neonates suspected to have sepsis, but with sterile bacterial cultures. Results Cases were identified in each of three sequential years in a NICU with 800 to 900 admissions/year. Two cases were likely acquired perinatally; all were symptomatic with lethargy and poor feeding by age 5 to 10 days. All had signs of sepsis and/or meningitis; one progressed to periventricular leukomalacia and encephalomalacia. Two recovered from myocarditis after treatment that included IVIG 3 to 5 g/kg. Conclusion Neonates who appear septic without bacterial etiolog...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Neonatal Enterovirus Infection: Case Series of Clinical Sepsis and Positive Cerebrospinal Fluid Polymerase Chain Reaction Test with Myocarditis and Cerebral White Matter Injury Complications","attachmentId":69905058,"attachmentType":"pdf","work_url":"https://www.academia.edu/52829753/Neonatal_Enterovirus_Infection_Case_Series_of_Clinical_Sepsis_and_Positive_Cerebrospinal_Fluid_Polymerase_Chain_Reaction_Test_with_Myocarditis_and_Cerebral_White_Matter_Injury_Complications","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/52829753/Neonatal_Enterovirus_Infection_Case_Series_of_Clinical_Sepsis_and_Positive_Cerebrospinal_Fluid_Polymerase_Chain_Reaction_Test_with_Myocarditis_and_Cerebral_White_Matter_Injury_Complications"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="1" data-entity-id="14115115" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/14115115/Neonatal_enterovirus_infections_emphasis_on_risk_factors_of_severe_and_fatal_infections">Neonatal enterovirus infections: emphasis on risk factors of severe and fatal infections</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33115704" href="https://taiwan.academia.edu/LuanyinChang">Luan-yin Chang</a></div><p class="ds-related-work--metadata ds2-5-body-xs">The Pediatric Infectious Disease Journal, 2003</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Neonatal enterovirus infections: emphasis on risk factors of severe and fatal infections","attachmentId":44588972,"attachmentType":"pdf","work_url":"https://www.academia.edu/14115115/Neonatal_enterovirus_infections_emphasis_on_risk_factors_of_severe_and_fatal_infections","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/14115115/Neonatal_enterovirus_infections_emphasis_on_risk_factors_of_severe_and_fatal_infections"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="51075441" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/51075441/A_prospective_study_of_enterovirus_infection_in_Thai_infants_presenting_as_sepsis">A prospective study of enterovirus infection in Thai infants presenting as sepsis</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="174015979" href="https://chula.academia.edu/ThiravatHemachudha">Thiravat Hemachudha</a></div><p class="ds-related-work--abstract ds2-5-body-sm">Enterovirus infections are important causes of a sepsis-like syndromes in infants under 3 months of age. Most enterovirus infected patients presented with fever without localizing signs and rashes. Detection of enterovirus RNA by NASBA in serum and/or CSF represents a rapid method for the diagnosis of enterovirus infection in infants presenting with a sepsis-like syndrome.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"A prospective study of enterovirus infection in Thai infants presenting as sepsis","attachmentId":68930914,"attachmentType":"pdf","work_url":"https://www.academia.edu/51075441/A_prospective_study_of_enterovirus_infection_in_Thai_infants_presenting_as_sepsis","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/51075441/A_prospective_study_of_enterovirus_infection_in_Thai_infants_presenting_as_sepsis"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="3" data-entity-id="9440950" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/9440950/Neonatal_Enterovirus_Infections_Reported_to_the_National_Enterovirus_Surveillance_System_in_the_United_States_1983_2003">Neonatal Enterovirus Infections Reported to the National Enterovirus Surveillance System in the United States, 1983???2003</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="21993727" href="https://independent.academia.edu/NinoKhetsuriani">Nino Khetsuriani</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Pediatric Infectious Disease Journal, 2006</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Neonatal Enterovirus Infections Reported to the National Enterovirus Surveillance System in the United States, 1983???2003","attachmentId":35681503,"attachmentType":"pdf","work_url":"https://www.academia.edu/9440950/Neonatal_Enterovirus_Infections_Reported_to_the_National_Enterovirus_Surveillance_System_in_the_United_States_1983_2003","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/9440950/Neonatal_Enterovirus_Infections_Reported_to_the_National_Enterovirus_Surveillance_System_in_the_United_States_1983_2003"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="95575306" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/95575306/Enteroviral_Infections_in_Infants">Enteroviral Infections in Infants</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="203844642" href="https://independent.academia.edu/SrijanSingh51">Srijan Singh</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Newborn</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Enteroviral Infections in Infants","attachmentId":97719673,"attachmentType":"pdf","work_url":"https://www.academia.edu/95575306/Enteroviral_Infections_in_Infants","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/95575306/Enteroviral_Infections_in_Infants"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="5459453" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/5459453/Congenital_echovirus_21_infection_causing_fulminant_hepatitis_in_a_neonate">Congenital echovirus 21 infection causing fulminant hepatitis in a neonate</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="3756860" href="https://independent.academia.edu/DanielVirella">Daniel Virella</a></div><p class="ds-related-work--metadata ds2-5-body-xs">BMJ case reports, 2013</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Congenital echovirus 21 infection causing fulminant hepatitis in a neonate","attachmentId":32579106,"attachmentType":"pdf","work_url":"https://www.academia.edu/5459453/Congenital_echovirus_21_infection_causing_fulminant_hepatitis_in_a_neonate","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/5459453/Congenital_echovirus_21_infection_causing_fulminant_hepatitis_in_a_neonate"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="84137380" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/84137380/Diagnosis_of_Non_Polio_Enteroviral_Infections_in_Septic_Neonates_by_Polymerase_Chain_Reaction_Assays">Diagnosis of Non-Polio Enteroviral Infections in Septic Neonates by Polymerase Chain Reaction Assays</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="55253834" href="https://independent.academia.edu/SadafAsaei">Sadaf Asaei</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2016</p><p class="ds-related-work--abstract ds2-5-body-sm">Objective: The purpose of this study was to investigate the prevalence of non-polio enteroviral infections by quantitative and qualitative PCR assays in neonates 3-30 days old with clinical diagnosis of sepsis. Methods: The patients included all the neonates aged 3-30 days admitted with diagnosis of neonatal sepsis. Blood specimens, throat swabs, and in 60 cases CSF specimens were tested for Enteroviruses (EVs), using a quantitative RT-PCR assay. Alternate RT-PCR assays separated polio and non-polio enteroviruses. Demographic data including age, sex, type of feeding and gestational age were obtained. Results: As PCR results revealed, of the 177 neonates with clinical diagnosis of sepsis, one patient (0.55%) was positive for non-polio EVs in all of throat, serum and CSF samples. In 3 patients (1.7%), the results were positive for non-polio EVs in both throat and serum, while in15 (8.45%) others only throat samples were positive. Sex, age and gestational age had no significant relatio...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Diagnosis of Non-Polio Enteroviral Infections in Septic Neonates by Polymerase Chain Reaction Assays","attachmentId":107177157,"attachmentType":"pdf","work_url":"https://www.academia.edu/84137380/Diagnosis_of_Non_Polio_Enteroviral_Infections_in_Septic_Neonates_by_Polymerase_Chain_Reaction_Assays","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/84137380/Diagnosis_of_Non_Polio_Enteroviral_Infections_in_Septic_Neonates_by_Polymerase_Chain_Reaction_Assays"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="70598017" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/70598017/Enteroviral_Infections_in_the_First_Three_Months_of_Life">Enteroviral Infections in the First Three Months of Life</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="136500566" href="https://independent.academia.edu/AlbertoBerardi2">Alberto Berardi</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Pathogens</p><p class="ds-related-work--abstract ds2-5-body-sm">Enteroviruses (EVs) are an important source of infection in the paediatric age, with most cases concerning the neonatal age and early infancy. Molecular epidemiology is crucial to understand the circulation of main serotypes in a specific area and period due to their extreme epidemiological variability. The diagnosis of EVs infection currently relies on the detection of EVs RNA in biological samples (usually cerebrospinal fluid and plasma, but also throat swabs and feces) through a polymerase chain reaction assay. Although EVs infections usually have a benign course, they sometimes become life threatening, especially when symptoms develop in the first few days of life. Mortality is primarily associated with myocarditis, acute hepatitis, and multi-organ failure. Neurodevelopmental sequelae have been reported following severe infections with central nervous system involvement. Unfortunately, at present, the treatment of EVs infections is mainly supportive. The use of specific antivira...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Enteroviral Infections in the First Three Months of Life","attachmentId":80283223,"attachmentType":"pdf","work_url":"https://www.academia.edu/70598017/Enteroviral_Infections_in_the_First_Three_Months_of_Life","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/70598017/Enteroviral_Infections_in_the_First_Three_Months_of_Life"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="98023550" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/98023550/Characteristic_of_cardiac_and_neurological_forms_of_non_polio_enterovirus_infection">Characteristic of cardiac and neurological forms of non-polio enterovirus infection</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="119751657" href="https://independent.academia.edu/MehulSadadiwala">Mehul Sadadiwala</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Journal of Advances in Medicine, 2022</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Characteristic of cardiac and neurological forms of non-polio enterovirus infection","attachmentId":99488312,"attachmentType":"pdf","work_url":"https://www.academia.edu/98023550/Characteristic_of_cardiac_and_neurological_forms_of_non_polio_enterovirus_infection","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/98023550/Characteristic_of_cardiac_and_neurological_forms_of_non_polio_enterovirus_infection"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="125279470" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/125279470/Diagnostic_Difficulties_in_a_Case_of_Fetal_Ventricular_Tachycardia_Associated_with_Neonatal_COVID_Infection_Case_Report">Diagnostic Difficulties in a Case of Fetal Ventricular Tachycardia Associated with Neonatal COVID Infection: Case Report</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="118346013" href="https://independent.academia.edu/FAGARASANAMALIA">AMALIA FAGARASAN</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Journal of Environmental Research and Public Health, 2021</p><p class="ds-related-work--abstract ds2-5-body-sm">The clinical course of COVID in the pediatric population is considered to be much milder when compared to adults; however, the occurrence of severe and fatal forms of the disease in children is non-negligible, especially in patients with comorbidities such as prematurity or cardiac disease. We report a case of a newborn with sotalol-controlled fetal ventricular tachycardia, who was postnatally diagnosed with COVID infection. The myocardial injury was sustained on the basis of pericardial effusion, left ventricular dysfunction, rapid progression to coronary artery dilation, and an arrhythmic storm. We believe that, in our case, there is a significant overlap between fetal ventricular tachycardia, associated with impaired left ventricular function, and COVID infection, diagnosed after birth; both factors contribute to the myocardial dysfunction with a fulminant clinical evolution. To our knowledge, this is the first case describing neonatal myocardial dysfunction associated with SARS-...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Diagnostic Difficulties in a Case of Fetal Ventricular Tachycardia Associated with Neonatal COVID Infection: Case Report","attachmentId":119352008,"attachmentType":"pdf","work_url":"https://www.academia.edu/125279470/Diagnostic_Difficulties_in_a_Case_of_Fetal_Ventricular_Tachycardia_Associated_with_Neonatal_COVID_Infection_Case_Report","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/125279470/Diagnostic_Difficulties_in_a_Case_of_Fetal_Ventricular_Tachycardia_Associated_with_Neonatal_COVID_Infection_Case_Report"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--sticky-ctas","attachmentId":112966821,"attachmentType":"pdf","workUrl":null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--sticky-ctas","attachmentId":112966821,"attachmentType":"pdf","workUrl":null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_112966821" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. 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PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/78586097/Successful_containment_of_horizontal_enterovirus_infection_in_a_neonatal_unit_in_Singapore_through_diagnosis_by_polymerase_chain_reaction_PCR_and_direct_sequence_analysis"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="7" data-entity-id="96416838" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/96416838/Outbreak_of_Life_Threatening_Coxsackievirus_B1_Myocarditis_in_Neonates">Outbreak of Life‐Threatening Coxsackievirus B1 Myocarditis in Neonates</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author 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