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id="RCAUserType" /> <input type="hidden" name="ctl00$RootHolder$UserId" id="UserId" /> <input type="hidden" name="ctl00$RootHolder$IsCurrentUser" id="IsCurrentUser" /> <div class="search-result-container cl"> <div class="search-centered cl"> <div class="search-result-center-container cl"> <div class="left-part"> <div id="RootHolder_ExportContainer" class="export-container"> <div class="dxbButton_MetropolisBlue DefaultButton-Oral dxbButtonSys dxbTSys" id="RootHolder_DownloadArticle" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxb"> <input id="RootHolder_DownloadArticle_I" class="dxb-hb" value="Download" type="button" name="ctl00$RootHolder$DownloadArticle" /><span class="dx-vam">Download</span> </div> </div><script id="dxss_1963926087" type="text/javascript">  </script> </div> <div class="mnavbar"> <table class="total-count-container cl"> <tr> <td> <a href="/" target="_blank" class="white-link">Total Articles</a> </td> </tr> </table> </div> <div class="mnavbox"> <label id="RootHolder_TotalCountText" class="total-count-text">22902</label> <br /> <label style="font-size: 14px;">(from Reference Citation Analysis)</label> <div id="RootHolder_SearchArticlePDFContainer" style="padding-top: 1rem;"> <input name="ctl00$RootHolder$ArticlesWithPdf" type="checkbox" id="RootHolder_ArticlesWithPdf" class="ArticlesWithPdf" onclick="SearchArticleWithPDF();" /> <label for="ArticlesWithPdf">Article PDFs (4108)</label> </div> <div id="RootHolder_SearchTCContainer" style="padding-top: 1rem;"> <input name="ctl00$RootHolder$ArticlesWithTC" type="checkbox" id="RootHolder_ArticlesWithTC" class="ArticlesWithTC" onclick="SearchArticleWithTC();" /> <label for="ArticlesWithTC">Cited by ≥ 1 (13469)</label> </div> </div> <div class="mnavbar" id="SearchedNameTitle"> <div> Searched Name </div> </div> <div class="mnavbox" id="SearchedNameText"> <label id="RootHolder_SearchTermText" class="search-term-text">Inflammation/metabolism</label> </div> <div 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sortedby-list"> <li> <a href="javascript:SubmitSingleFacetSearch('create','6');">Today (<span id="indexCount6"></span>)</a> </li> <li> <a href="javascript:SubmitSingleFacetSearch('create','5');">Yesterday (<span id="indexCount5"></span>)</a> </li> <li> <a href="javascript:SubmitSingleFacetSearch('create','4');">This Week (<span id="indexCount4"></span>)</a> </li> <li> <a href="javascript:SubmitSingleFacetSearch('create','3');">Last Week (<span id="indexCount3"></span>)</a> </li> <li> <a href="javascript:SubmitSingleFacetSearch('create','2');">Current Month (<span id="indexCount2"></span>)</a> </li> <li> <a href="javascript:SubmitSingleFacetSearch('create','1');">Last Month (<span id="indexCount1"></span>)</a> </li> </ul> </div> <div id="journalFacetContainer"> <div class="mnavbar"> <div> Publication Titles </div> </div> <div class="mnavbox"> <div id="journalFacetItemContainer"> </div> <div class="refine-btn-container cl"> <a href="javascript:ShowResultItems('journal');" class="refine-link-btn" target="_self">Show more</a>   <a href="javascript:SubmitFacetSearch();" class="refine-link-btn refine-link-btn-right" name="refinejournalcheck" target="_self">Refine</a> </div> </div> </div> <div id="fundFacetContainer"> <div class="mnavbar"> <div> Grant Agencies </div> </div> <div class="mnavbox"> <div id="fundFacetItemContainer"> </div> <div class="refine-btn-container cl"> <a href="javascript:ShowResultItems('fund');" class="refine-link-btn" target="_self">Show more</a>   <a href="javascript:SubmitFacetSearch();" class="refine-link-btn refine-link-btn-right" name="refinefundcheck" target="_self">Refine</a> </div> </div> </div> <div id="subjectFacetContainer"> <div class="mnavbar"> <div> Category </div> </div> <div class="mnavbox"> <div id="subjectFacetItemContainer"> </div> <div class="refine-btn-container cl"> <a href="javascript:ShowResultItems('subject');" class="refine-link-btn" target="_self">Show more</a>   <a href="javascript:SubmitFacetSearch();" class="refine-link-btn refine-link-btn-right" name="refinesubjectcheck" target="_self">Refine</a> </div> </div> </div> </div> </div> <div class="right-part"> <div class="mnavbar" style="margin-bottom: 0.625rem;"> <div> Journal Articles </div> </div> <table class="article-result-list cl"> <thead> <tr> <td> <span class="dxeBase_MetropolisBlue" id="RootHolder_SearchResultList_NumberTitle">Number</span> </td> <td> <span class="dxeBase_MetropolisBlue" id="RootHolder_SearchResultList_NameTitle">Citation Analysis</span> </td> </tr> </thead> <tbody> <tr id="articlerow1"> <td style="min-width: 40px; text-align: center;"> 1 </td> <td> <div id="citation1" class="article-citation"> <b>de Siqueira Patriota LL</b>, de Lima BRF, de Oliveira Marinho A, da Costa JA, de Lucena ALA, Paiva PMG, Napoleão DC, Cavalcanti JVFL, Pereira MC, Napoleão TH, da Rosa MM. Moringa oleifera Lam. seed lectin (WSMoL) reduces chronic stress-induced anxiety and depression in mice by lessening inflammation and balancing brain chemicals. <em class='incite-journal-name' onclick='ShowInCiteJournal(3378);'>Behav Brain Res</em> 2025;<b>477</b>:115318. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39481762' target='_blank'>39481762</a> DOI: <a href='https://dx.doi.org/10.1016/j.bbr.2024.115318' target='_blank'>10.1016/j.bbr.2024.115318</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.bbr.2024.115318','39481762', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(1);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(1);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(1);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.bbr.2024.115318' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3378);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/18/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/09/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/27/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/02/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv1" value="10.1016/j.bbr.2024.115318" /> <div style="display: none" id="articleAbstract1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Phyto-based treatments for anxiety and depression are gaining attention. The efficacy of the water-soluble Moringa oleifera seed lectin (WSMoL) in reducing acute anxiolytic and depressive-like behaviors in mice has been previously demonstrated. In the present study, it was evaluated the effects of WSMoL on reducing anxiety and depressive-like symptoms in a mouse model of unpredictable chronic mild stress (UCMS). The animals were divided into groups and exposed to a four-week UCMS regimen. Following this, the mice received daily intraperitoneal injections of vehicle (non-stressed and UCMS control groups), WSMoL (2 or 4 mg/kg), or fluoxetine (10 mg/kg) for 21 days. Neurobehavioral tests included the open field test and elevated plus maze test to assess anxiety-like behavior, and the tail suspension test and sucrose preference test to evaluate depression-like behavior. Biochemical analyses measured serum corticosterone and cytokines as well brain levels of cytokines and monoamines. All tests indicated that WSMoL significantly (p < 0.05) reversed the anxiety and depression-like behaviors induced by UCMS. The stress protocol increased serum corticosterone levels and WSMoL treatment was not able to normalize corticosterone secretion. WSMoL treatment reduced serum and brain levels of IL-2, IL-6, and TNF-α, indicating reduced neuroinflammation, and increased brain levels of dopamine, serotonin, and noradrenaline. In summary, WSMoL mitigated UCMS-induced anxiety and depression-like behaviors by reducing neuroinflammation and modulating brain monoamine levels. </div> <a href="javascript:ShowArticleAbstract(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chronic+stress%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chronic stress</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Horseradish+tree%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Horseradish tree</a></li><li><a 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<b>Xiong S</b>, Xu C, Yang C, Luo H, Xie J, Xia B, Zhang Z, Liao Y, Li C, Li Y, Lin L. FuKe QianJin capsule alleviates endometritis via inhibiting inflammation and pyroptosis through modulating TLR4/ NF-κB /NLRP3 pathway. <em>JOURNAL OF ETHNOPHARMACOLOGY</em> 2025;<b>337</b>:118962. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39426577' target='_blank'>39426577</a> DOI: <a href='https://dx.doi.org/10.1016/j.jep.2024.118962' target='_blank'>10.1016/j.jep.2024.118962</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.jep.2024.118962','39426577', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(2);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(2);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(2);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.jep.2024.118962' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/15/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/07/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/16/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/21/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv2" value="10.1016/j.jep.2024.118962" /> <div style="display: none" id="articleAbstract2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">ETHNOPHARMACOLOGICAL RELEVANCE</div><div class="abstract-content">Fuke Qianjin Capsule (FKC), a traditional Chinese medicine commonly employed for treating endometritis, lacks reported treatment mechanisms. </div><div class="abstract-label">AIM OF THE STUDY</div><div class="abstract-content">The aim of the present study was to explore the role and mechanism of FKC in lipopolysaccharide (LPS)-induced endometritis. </div><div class="abstract-label">MATERIALS AND METHODS</div><div class="abstract-content">The main active ingredients of FKC were identified via high-performance liquid chromatography (HPLC) in conjunction with standard substances. Prior to endometritis induction, Sprague Dawley female rats received FKC for 7 days. The endometritis model was established through an intrauterine injection of 1 mg/kg LPS. Concurrently, an LPS-induced RAW264.7 cell inflammation model was utilized, in which the cells were treated with serum containing Fuke Qianjin Capsule. Pathological alterations in the endometrium were assessed via H&E staining and transmission electron microscopy (TEM). The contents of MPO in uterine tissues, and NO release in cells, along with the secretion of IL-18, IL-1β, IL-6, and TNF-α in both tissues and cells, were determined via assay kits. The mRNA levels of Nlrp3, Caspase-1, Gsdmd, and Il-1β in uterine tissues and cells were analyzed via qPCR. The protein levels of TLR4, p65, p-P65, NLRP3, Caspase-1, GSDMD, and IL-1β in these samples were evaluated through Western blot analysis. Immunofluorescence was used to assess the protein levels of p-P65 and NLRP3 in uterine tissues and cells. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">Five primary active components of FKC were identified. Treatment with FKC in vivo mitigated endometrial pathological damage and significantly decreased the levels of MPO, IL-18, IL-1β, IL-6, and TNF-α, as well as the levels of Nlrp3, Caspase-1, Gsdmd, and Il-1β mRNA in tissue samples. Treatment with FKC inhibited the expression of TLR4, p-P65, NLRP3, Caspase-1, GSDMD, and IL-1β, as well as reduced NLRP3 protein fluorescence intensity, and inhibited P65 phosphorylation. In vitro findings demonstrated that FKC-containing serum reduced IL-18, IL-1β, IL-6, and TNF-α levels, as well as reduced Nlrp3, Caspase-1, Gsdmd, and Il-1β mRNA levels. In addition, FKC-containing serum inhibited the protein expression of TLR4, p-P65, NLRP3, Caspase-1, GSDMD, and IL-1β. FKC-containing serum also reduced NLRP3 protein fluorescence intensity and suppressed P65 phosphorylation. </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">FKC reverses the LPS induced NLRP3 inflammasome activation, and mitigates inflammation and pyroptosis through the modulation of the TLR4/NF-κB/NLRP3 pathway, thereby alleviating endometritis. </div> <a href="javascript:ShowArticleAbstract(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Endometritis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Endometritis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22FuKe+QianJin+capsule%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">FuKe QianJin capsule</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22LPS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">LPS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NLRP3%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">NLRP3</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pyroptosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pyroptosis</a></li></ul> <a href="javascript:ShowArticleKeywords(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NLR+Family%2c+Pyrin+Domain-Containing+3+Protein%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">NLR Family, Pyrin Domain-Containing 3 Protein/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Toll-Like+Receptor+4%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Toll-Like Receptor 4/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Endometritis%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Endometritis/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Drugs%2c+Chinese+Herbal%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Drugs, Chinese Herbal/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pyroptosis%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pyroptosis/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RAW+264.7+Cells%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RAW 264.7 Cells</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NF-kappa+B%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">NF-kappa B/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Signal+Transduction%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Signal Transduction/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Lipopolysaccharides%2ftoxicity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Lipopolysaccharides/toxicity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anti-Inflammatory+Agents%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anti-Inflammatory Agents/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anti-Inflammatory+Agents%2ftherapeutic+use%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anti-Inflammatory Agents/therapeutic use</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/metabolism</a></li></ul> <a href="javascript:ShowArticleMeSH(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(2);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow3"> <td style="min-width: 40px; text-align: center;"> 3 </td> <td> <div id="citation3" class="article-citation"> <b>Deng H</b>, Zhou P, Wang J, Zeng J, Yu C. CircRNA expression profiling of the rat thalamus in temporomandibular joint chronic inflammatory pain. <em class='incite-journal-name' onclick='ShowInCiteJournal(9624);'>Gene</em> 2025;<b>934</b>:149024. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39433265' target='_blank'>39433265</a> DOI: <a href='https://dx.doi.org/10.1016/j.gene.2024.149024' target='_blank'>10.1016/j.gene.2024.149024</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.gene.2024.149024','39433265', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(3);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(3);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(3);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.gene.2024.149024' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(9624);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/21/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/17/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/18/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/23/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv3" value="10.1016/j.gene.2024.149024" /> <div style="display: none" id="articleAbstract3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Orofacial pain (OFP) induced by temporomandibular disorders (TMDs) is prevalent, affecting approximately 4.6 % of the population. One specific type of TMD is temporomandibular osteoarthritis (TMJOA), a common degenerative disease that significantly impacts patients' quality of life. Differentially expressed circular RNAs (DEcircRNAs) in the thalamus, which serves as a relay station in the orofacial pain transmission pathway, may play a crucial role and serve as potential target markers for inflammation and the progression of inflammatory pain in TMJOA. The aim of this study was to investigate the expression profile of circRNAs in the thalamus of TMJOA. We obtained the circRNA expression profile from the thalamus of a rat model of TMJOA through high-throughput sequencing (HT-seq) and further validated their expression using reverse transcription real-time polymerase chain reaction (RT-qPCR), followed by bioinformatics analysis of the expression data. A total of 425 circRNAs (DESeq2 p- value < 0.05, |log2FoldChange| > 0.0) were identified as significantly differentially expressed by RNA-Seq, comprising 188 up-regulated and 237 down-regulated circRNAs. After validation via RT-qPCR, we employed miRanda software to predict the binding sites of miRNAs for the identified circRNAs to further explore the functions of DEcircRNAs. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses revealed that DEcircRNAs were primarily enriched in pathways and functions related to synapse development, protein signaling and modification, 'Circadian entertainment', the 'MAPK signaling pathway', and 'Glutamatergic synapse'. These findings suggest that DEcircRNAs in the thalamus play a significant role in the progression of TMJOA and may serve as promising candidate molecular targets for gene therapy. </div> <a href="javascript:ShowArticleAbstract(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Central+sensitization%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Central sensitization</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chronic+inflammatory+pain%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chronic inflammatory pain</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22CircRNA%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">CircRNA</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22TMJOA%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">TMJOA</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Thalamus%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Thalamus</a></li></ul> <a href="javascript:ShowArticleKeywords(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RNA%2c+Circular%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RNA, Circular/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RNA%2c+Circular%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RNA, Circular/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a 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style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(3);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow4"> <td style="min-width: 40px; text-align: center;"> 4 </td> <td> <div id="citation4" class="article-citation"> <b>Heydari R</b>, Khosravifar M, Abiri S, Dashtbin S, Alvandi A, Nedaei SE, Salimi Z, Zarei F, Abiri R. A domestic strain of Lactobacillus rhamnosus attenuates cognitive deficit and pro-inflammatory cytokine expression in an animal model of Alzheimer's disease. <em class='incite-journal-name' onclick='ShowInCiteJournal(3378);'>Behav Brain Res</em> 2025;<b>476</b>:115277. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39343242' target='_blank'>39343242</a> DOI: <a href='https://dx.doi.org/10.1016/j.bbr.2024.115277' target='_blank'>10.1016/j.bbr.2024.115277</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.bbr.2024.115277','39343242', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(4);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(4);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(4);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.bbr.2024.115277' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3378);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 04/22/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/27/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/01/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv4" value="10.1016/j.bbr.2024.115277" /> <div style="display: none" id="articleAbstract4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Microbiome dysbiosis plays a significant role in neuroinflammation and Alzheimer's disease (AD). Therefore, gut microbiome restoration using appropriate probiotics may be beneficial in alleviating AD features. In this study, we investigated the effects of a domestic strain of Lactobacillus rhamnosus (L. rhamnosus) on spatial memory, and cytokines expression in an inflammation-based AD model. </div><div class="abstract-label">METHOD</div><div class="abstract-content">Male Wistar rats were randomly divided into four groups (six animals per group) of control, L. rhamnosus-only, D-galactose (D-gal)-only, and D-gal + L. rhamnosus. Spatial learning and memory were assessed using the Morris water maze test. IL-1β, IL-6, and TNF-α expression levels were measured using Real-Time qPCR. A significance level of 0.05 was used for statistical analysis. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">In contrast to the D-gal + L. rhamnosus-treated group, D-gal only treated group showed impaired memory in MWM test compared to the control group. Additionally, D-gal treatment resulted in an increase in IL-1β and TNF-α levels and a decrease in IL-6 levels, which was not statistically significant. However, the TNF-α level was significantly decreased in D-gal + L. rhamnosus-treated group compared to D-gal-only treated group (P < 0.05). Also, IL-6 level was significantly lower in D-gal + L. rhamnosus-treated group compared to control group (P < 0.05). </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">These results suggest that the domestic L. rhamnosus might positively impact cognitive deficit and neuroinflammation. Further studies are suggested to investigate the specific mechanisms mediating the effects of L. rhamnosus on cognitive functions and neuroinflammation in animal models of AD. </div> <a href="javascript:ShowArticleAbstract(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Alzheimer%e2%80%99s+disease%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Alzheimer’s disease</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Lactobacillus+rhamnosus%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Lactobacillus rhamnosus</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cytokines%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cytokines</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22learning%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">learning</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22memory%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">memory</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22probiotic%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">probiotic</a></li></ul> <a href="javascript:ShowArticleKeywords(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh4" class="article-abstract"> <b style="display: block; 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padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(4);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow5"> <td style="min-width: 40px; text-align: center;"> 5 </td> <td> <div id="citation5" class="article-citation"> <b>Mahmoudi J</b>, Kazmi S, Vatandoust S, Athari SZ, Sadigh-Eteghad S, Morsali S, Bahari L, Ahmadi M, Hosseini L, Farajdokht F. Coenzyme Q10 and vitamin E alleviate heat stress-induced mood disturbances in male mice: Modulation of inflammatory pathways and the HPA axis. <em class='incite-journal-name' onclick='ShowInCiteJournal(3378);'>Behav Brain Res</em> 2025;<b>476</b>:115259. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39303989' target='_blank'>39303989</a> DOI: <a href='https://dx.doi.org/10.1016/j.bbr.2024.115259' target='_blank'>10.1016/j.bbr.2024.115259</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.bbr.2024.115259','39303989', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(5);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(5);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(5);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.bbr.2024.115259' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3378);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/04/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/18/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/22/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv5" value="10.1016/j.bbr.2024.115259" /> <div style="display: none" id="articleAbstract5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Heat stress, as an environmental stressor, can lead to temperature dysregulation and neuroinflammation, causing depression and anxiety by disrupting brain physiology and functional connectivity. This study looked at how co-enzyme Q10 (Q10) and vitamin E (Vit E), alone and together, affected heat stress-caused anxiety and depression symptoms and inflammation in male mice. Five groups were utilized in the study: control, heat stress (NS), Q10, Vit E, and the combination group (Q10+Vit E). The mice were subjected for 15 min/day to a temperature of 43°C for 14 consecutive days, followed by daily treatments for two weeks with either normal saline, Q10 (500 mg/kg), Vit E (250 mg/kg), or their combination. The forced swimming test (FST) and tail suspension test (TST) were employed to evaluate despair behavior, whereas the elevated plus maze (EPM) and open field test (OFT) were used to assess anxious behaviors. Subsequently, the animals were sacrificed, and serum corticosterone levels, protein expression of inflammasome-related proteins, and hsp70 gene expression were evaluated in the prefrontal cortex (PFC). The study revealed that treatment with Vit E and Q10, alone or together, provided anxiolytic and antidepressant effects in the heat-stress-subjected animals. Also, giving Vit E and Q10 alone or together greatly lowered serum corticosterone levels. In the PFC, they also lowered the levels of hsp70 mRNA and NF-κB, caspase 1, NLRP3, and IL-1β proteins. It is speculated that treatment with Q10 and Vit E can attenuate heat stress-associated anxious and depressive responses by inhibiting the inflammatory pathways and modulating the hypothalamus-pituitary-adrenal axis. </div> <a href="javascript:ShowArticleAbstract(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anxiety%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anxiety</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Corticosterone%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Corticosterone</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Thermal+stress%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Thermal stress</a></li></ul> <a href="javascript:ShowArticleKeywords(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a 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Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22HSP70+Heat-Shock+Proteins%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">HSP70 Heat-Shock Proteins/metabolism</a></li></ul> <a href="javascript:ShowArticleMeSH(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(5);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow6"> <td style="min-width: 40px; text-align: center;"> 6 </td> <td> <div id="citation6" class="article-citation"> <b>Kumorkiewicz-Jamro A</b>, Pachulicz RJ, Fitter S, Górska R, Duggan J, Vandyke K, Pukala TL, Wybraniec S, Zannettino ACW. Atriplex hortensis var. 'rubra' extracts and purified amaranthin-type pigments reduce oxidative stress and inflammatory response in LPS-stimulated RAW264.7 cells. <em class='incite-journal-name' onclick='ShowInCiteJournal(9277);'>Food Chem</em> 2025;<b>462</b>:140920. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39208732' target='_blank'>39208732</a> DOI: <a href='https://dx.doi.org/10.1016/j.foodchem.2024.140920' target='_blank'>10.1016/j.foodchem.2024.140920</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.foodchem.2024.140920','39208732', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(6);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(6);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(6);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.foodchem.2024.140920' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(9277);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 03/24/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/04/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/17/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/04/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv6" value="10.1016/j.foodchem.2024.140920" /> <div style="display: none" id="articleAbstract6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">The use of direct injection ion mobility mass spectrometry (DI-IM-MS) to detect and identify betacyanin pigments in A. hortensis 'rubra' extracts was explored for the first time, with results compared to conventional LC-MS/MS analysis. The anti-inflammatory activities of leaf and seed extracts, alongside purified amaranthin and celosianin pigments, were investigated using a model of lipopolysaccharide (LPS)-activated murine macrophages. Extracts and purified pigments significantly inhibited the production of prostaglandin E2 and NO by up to 90% and 70%, respectively, and reduced the expression of Il6, Il1b, Nos2, and Cox2. Leaf and seed extracts also decreased secretion of Il6 and Il1b cytokines and reduced protein levels of Nos2 and Cox2. Furthermore, extracts and purified pigments demonstrated potent dose-dependent radical scavenging activity in a cellular antioxidant activity assay (CAA) without any cytotoxic effects. Our research highlights the promising biological potential of edible, climate-resilient A. hortensis 'rubra' as a valuable source of bioactive compounds. </div> <a href="javascript:ShowArticleAbstract(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anti-inflammatory+activity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anti-inflammatory activity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Antioxidant+activity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Antioxidant activity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Atriplex+hortensis+%e2%80%98rubra%e2%80%99%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Atriplex hortensis ‘rubra’</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Betalains%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Betalains</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ion+mobility-mass+spectrometry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ion mobility-mass spectrometry</a></li></ul> <a href="javascript:ShowArticleKeywords(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Plant+Extracts%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Plant Extracts/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Plant+Extracts%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Plant Extracts/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Plant+Extracts%2fisolation+%26amp%3b+purification%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Plant Extracts/isolation & purification</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RAW+264.7+Cells%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RAW 264.7 Cells</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Oxidative+Stress%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Oxidative Stress/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Macrophages%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Macrophages/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Macrophages%2fimmunology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Macrophages/immunology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Lipopolysaccharides%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Lipopolysaccharides/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anti-Inflammatory+Agents%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anti-Inflammatory Agents/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anti-Inflammatory+Agents%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anti-Inflammatory Agents/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anti-Inflammatory+Agents%2fisolation+%26amp%3b+purification%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anti-Inflammatory Agents/isolation & purification</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cyclooxygenase+2%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cyclooxygenase 2/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cyclooxygenase+2%2fimmunology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cyclooxygenase 2/immunology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cyclooxygenase+2%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cyclooxygenase 2/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Tandem+Mass+Spectrometry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Tandem Mass Spectrometry</a></li></ul> <a href="javascript:ShowArticleMeSH(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(6);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow7"> <td style="min-width: 40px; text-align: center;"> 7 </td> <td> <div id="citation7" class="article-citation"> <b>Bradić I</b>, Kuentzel KB, Pirchheim A, Rainer S, Schwarz B, Trauner M, Larsen MR, Vujić N, Kratky D. From LAL-D to MASLD: Insights into the role of LAL and Kupffer cells in liver inflammation and lipid metabolism. <em class='incite-journal-name' onclick='ShowInCiteJournal(168092);'>Biochim Biophys Acta Mol Cell Biol Lipids</em> 2025;<b>1870</b>:159575. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39486573' target='_blank'>39486573</a> DOI: <a href='https://dx.doi.org/10.1016/j.bbalip.2024.159575' target='_blank'>10.1016/j.bbalip.2024.159575</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.bbalip.2024.159575','39486573', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(7);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(7);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(7);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.bbalip.2024.159575' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(168092);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 04/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/04/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv7" value="10.1016/j.bbalip.2024.159575" /> <div style="display: none" id="articleAbstract7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent liver pathology worldwide, closely associated with obesity and metabolic disorders. Increasing evidence suggests that macrophages play a crucial role in the development of MASLD. Several human studies have shown an inverse correlation between circulating lysosomal acid lipase (LAL) activity and MASLD. LAL is the sole enzyme known to degrade cholesteryl esters (CE) and triacylglycerols in lysosomes. Consequently, these substrates accumulate when their enzymatic degradation is impaired due to LAL deficiency (LALD). This study aimed to investigate the role of hepatic LAL activity and liver-resident macrophages (i.e., Kupffer cells (KC)) in MASLD. To this end, we analyzed lipid metabolism in hepatocyte-specific (hep)Lal-/- mice and depleted KC with clodronate treatment. When fed a high-fat/high-cholesterol diet (HF/HCD), hepLal-/- mice exhibited CE accumulation and an increased number of macrophages in the liver and significant hepatic inflammation. KC were depleted upon clodronate administration, whereas infiltrating/proliferating CD68-expressing macrophages were less affected. This led to exacerbated hepatic CE accumulation and dyslipidemia, as evidenced by increased LDL-cholesterol concentrations. Along with proteomic analysis of liver tissue, these findings indicate that hepatic LAL-D in HF/HCD-fed mice leads to macrophage infiltration into the liver and that KC depletion further exacerbates hepatic CE concentrations and dyslipidemia. </div> <a href="javascript:ShowArticleAbstract(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Clodronate%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Clodronate</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Kupffer+cell+depletion%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Kupffer cell depletion</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Liver+fibrosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Liver fibrosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Lysosomal+acid+lipase+deficiency%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Lysosomal acid lipase deficiency</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Metabolic+dysfunction-associated+steatotic+liver+disease%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Metabolic dysfunction-associated steatotic liver disease</a></li></ul> <a href="javascript:ShowArticleKeywords(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Kupffer+Cells%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Kupffer Cells/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Kupffer+Cells%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Kupffer Cells/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Lipid+Metabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Lipid Metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sterol+Esterase%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sterol Esterase/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sterol+Esterase%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sterol Esterase/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Liver%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Liver/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Liver%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Liver/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%2c+Knockout%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice, Knockout</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Fatty+Liver%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Fatty Liver/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Fatty+Liver%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Fatty Liver/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Fatty+Liver%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Fatty Liver/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%2c+Inbred+C57BL%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice, Inbred C57BL</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cholesterol+Esters%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cholesterol Esters/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diet%2c+High-Fat%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diet, High-Fat/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hepatocytes%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hepatocytes/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hepatocytes%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hepatocytes/pathology</a></li></ul> <a href="javascript:ShowArticleMeSH(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(7);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow8"> <td style="min-width: 40px; text-align: center;"> 8 </td> <td> <div id="citation8" class="article-citation"> <b>Liu Y</b>, Wu Q, Huang Z, Zhou D, Cai C, Luo W, Feng P. TLR4 Inhibitor TAK-242 Protected Henoch-Schonlein Purpura Nephritis in Rats by Regulating Inflammatory Response and Immune Competence via NF- κB/NLRP3 Signalling. <em class='incite-journal-name' onclick='ShowInCiteJournal(169839);'>Clin Exp Pharmacol Physiol</em> 2025;<b>52</b>:e70008. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39564921' target='_blank'>39564921</a> DOI: <a href='https://dx.doi.org/10.1111/1440-1681.70008' target='_blank'>10.1111/1440-1681.70008</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1111/1440-1681.70008','39564921', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(8);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(8);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(8);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(8);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1111/1440-1681.70008' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(169839);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 01/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/10/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/20/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/21/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv8" value="10.1111/1440-1681.70008" /> <div style="display: none" id="articleAbstract8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">This study aimed to explore the effect of toll-like receptor 4 (TLR4)/nuclear factor-kappa B (NF-κB)/NOD-like receptor thermal protein domain-associated protein 3 (NLRP3) signalling on Henoch-Schonlein purpura nephritis (HSPN). We established a HSPN rat model in a high-altitude hypoxic (HH) environment. Renal tissue lesions were observed by haematoxylin and Eosin (H&E) staining and terminal deoxynucleotidyl transferase-mediated dUTP nick end labelling (TUNEL), CD20-postive B cells and CD68-postive macrophage cells were detected by immunohistochemistry, T-cell activation was detected by flow cytometry and toll-like receptor 4 (TLR4)/nuclear factor-kappa B (NF-κB)/NOD-like receptor thermal protein domain associated protein 3 (NLRP3) signalling was detected by western blot. TAK-242 inhibited the expression of TLR4/NF-κB/NLRP3 signalling related-proteins, decreased the levels of 24 h urinary protein, serum creatinine, circular immune complex (CIC) and kidney immunoglobulin A (IgA), and improved renal histopathological damage in HH-HSPN rats. Furthermore, TAK-242 attenuated the infiltration of CD20 and CD68 into the kidney and increased the percentage of CD3+, CD4+ and CD4+/CD8+ cells in the blood of HH-HSPN rats. The study revealed that suppressing TLR4/NF-κB/NLRP3 signalling improved renal function and histopathological damage, and this improvement was related to inhibiting the inflammatory response and enhancing immune competence. </div> <a href="javascript:ShowArticleAbstract(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Henoch%e2%80%93Schonlein+purpura+nephritis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Henoch–Schonlein purpura nephritis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22TLR4+inhibitor+TAK%e2%80%90242%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">TLR4 inhibitor TAK‐242</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22TLR4%2fNF%e2%80%90%ce%baB%2fNLRP3+signalling%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">TLR4/NF‐κB/NLRP3 signalling</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22high%e2%80%90altitude+hypoxia%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">high‐altitude hypoxia</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22immunoglobulin+A+nephropathy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">immunoglobulin A nephropathy</a></li></ul> <a href="javascript:ShowArticleKeywords(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22IgA+Vasculitis%2fimmunology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">IgA Vasculitis/immunology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22IgA+Vasculitis%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">IgA Vasculitis/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NLR+Family%2c+Pyrin+Domain-Containing+3+Protein%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">NLR Family, Pyrin Domain-Containing 3 Protein/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NLR+Family%2c+Pyrin+Domain-Containing+3+Protein%2fantagonists+%26amp%3b+inhibitors%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">NLR Family, Pyrin Domain-Containing 3 Protein/antagonists & inhibitors</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NF-kappa+B%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">NF-kappa B/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NF-kappa+B%2fantagonists+%26amp%3b+inhibitors%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">NF-kappa B/antagonists & inhibitors</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Toll-Like+Receptor+4%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Toll-Like Receptor 4/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Toll-Like+Receptor+4%2fantagonists+%26amp%3b+inhibitors%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Toll-Like Receptor 4/antagonists & inhibitors</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Signal+Transduction%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Signal Transduction/drug effects</a></li><li><a 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China</a></li></ul> <a href="javascript:ShowArticleGrant(8);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow9"> <td style="min-width: 40px; text-align: center;"> 9 </td> <td> <div id="citation9" class="article-citation"> <b>Wei RM</b>, Zhang MY, Fang SK, Liu GX, Hu F, Li XY, Zhang KX, Zhang JY, Liu XC, Zhang YM, Chen GH. Melatonin attenuates intermittent hypoxia-induced cognitive impairment in aged mice: The role of inflammation and synaptic plasticity. <em class='incite-journal-name' onclick='ShowInCiteJournal(19918);'>Psychoneuroendocrinology</em> 2025;<b>171</b>:107210. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39378690' target='_blank'>39378690</a> DOI: <a href='https://dx.doi.org/10.1016/j.psyneuen.2024.107210' target='_blank'>10.1016/j.psyneuen.2024.107210</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.psyneuen.2024.107210','39378690', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(9);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(9);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(9);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.psyneuen.2024.107210' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(19918);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.editorialmanager.com/pnec/default.aspx?pg=mainpage.html' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 10/29/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/08/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/02/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/10/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv9" value="10.1016/j.psyneuen.2024.107210" /> <div style="display: none" id="articleAbstract9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Intermittent hypoxia (IH), a major pathophysiologic alteration in obstructive sleep apnea syndrome (OSAS), is an important contributor to cognitive impairment. Increasing research suggests that melatonin has anti-inflammatory properties and improves functions related to synaptic plasticity. However, it is unclear whether melatonin has a protective effect against OSAS-induced cognitive dysfunction in aged individuals and the involved mechanisms are also unclear. Therefore, in the study, the effects of exposure to IH alone and IH in combination with daily melatonin treatment were investigated in C57BL/6 J mice aged 18 months. Assessment of the cognitive ability of mice in a Morris water maze showed that melatonin attenuated IH-induced impairment of learning and memory in aged mice. Enzyme-linked immunosorbent assay, polymerase chain reaction, and western blotting molecular techniques showed that melatonin treatment reduced the levels of the proinflammatory cytokines, interleukin-1β, interleukin-6, and tumor necrosis factor-α, decreased the levels of NOD-like receptor thermal protein domain associated protein 3 and nuclear factor kappa-B, lowered the levels of ionized calcium-binding adapter molecule 1 and glial fibrillary acidic protein, and increased the levels of the synaptic proteins, activity-regulated cytoskeleton-associated protein, growth-associated protein-43, postsynaptic density protein 95, and synaptophysin in IH-exposed mice. Moreover, electrophysiological results showed that melatonin ameliorated the decline in long-term potentiation induced by IH. The results suggest that melatonin can ameliorate IH-induced cognitive deficits by inhibiting neuroinflammation and improving synaptic plasticity in aged mice. </div> <a href="javascript:ShowArticleAbstract(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cognitive+function%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cognitive function</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Intermittent+hypoxia%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Intermittent hypoxia</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Melatonin%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Melatonin</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuroinflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuroinflammation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Synaptic+plasticity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Synaptic plasticity</a></li></ul> <a href="javascript:ShowArticleKeywords(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a 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effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aging%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aging/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Long-Term+Potentiation%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Long-Term Potentiation/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Maze+Learning%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Maze Learning/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Models%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Models, Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cytokines%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cytokines/metabolism</a></li></ul> <a href="javascript:ShowArticleMeSH(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(9);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow10"> <td style="min-width: 40px; text-align: center;"> 10 </td> <td> <div id="citation10" class="article-citation"> <b>Liu Z</b>, Zheng X, Li N, Wang Z. Baicalein suppresses inflammation and attenuates acute lung injury by inhibiting glycolysis via HIF‑1α signaling. <em class='incite-journal-name' onclick='ShowInCiteJournal(17029);'>Mol Med Rep</em> 2025;<b>31</b>:18. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39513601' target='_blank'>39513601</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11564906' target='_blank'>PMC11564906</a> DOI: <a href='https://dx.doi.org/10.3892/mmr.2024.13383' target='_blank'>10.3892/mmr.2024.13383</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.3892/mmr.2024.13383','39513601', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(10);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(10);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(10);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.3892/mmr.2024.13383' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(17029);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/09/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/18/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/15/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv10" value="10.3892/mmr.2024.13383" /> <div style="display: none" id="articleAbstract10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Baicalein, a flavonoid monomer compound isolated from the dried root of the traditional Chinese herb Scutellaria baicalensis, has several pharmacological activities, such as anti‑inflammatory, anti‑angiogenic, antitumor, antimicrobial and antiviral properties. Acute lung injury (ALI) is characterized by injury of the alveolar epithelium and capillary endothelium, which results in decreased lung volume, decreased lung compliance, ventilation/perfusion mismatch, intrapulmonary edema, alveolar edema and even acute hypoxemic respiratory failure. The present study aimed to investigate the effects of baicalein on lung injury and inflammation. Bioinformatics analysis using network pharmacology predicted that the hypoxia inducible factor‑1α (HIF‑1α) and glycolysis signaling pathways were involved in the mechanism underlying the therapeutic effects of baicalein. Further in vitro and in vivo experiments, such as immunohistochemistry, immunofluorescence and PCR, verified that baicalein could inhibit HIF‑1α signaling, thus suppressing glycolysis, and improving inflammatory responses and ALI. Taken together, the results of the present study suggested that the anti‑inflammatory effects of baicalein on treating ALI were associated with its ability to suppress glycolysis via the HIF‑1α signaling pathway. </div> <a href="javascript:ShowArticleAbstract(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22HIF%e2%80%911%ce%b1+signaling%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">HIF‑1α signaling</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22acute+lung+injury%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">acute lung injury</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22baicalein%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">baicalein</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22glycolysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">glycolysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22inflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">inflammation</a></li></ul> <a href="javascript:ShowArticleKeywords(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Flavanones%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Flavanones/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Flavanones%2ftherapeutic+use%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Flavanones/therapeutic use</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Acute+Lung+Injury%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Acute Lung Injury/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Acute+Lung+Injury%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Acute Lung Injury/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Acute+Lung+Injury%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Acute Lung Injury/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypoxia-Inducible+Factor+1%2c+alpha+Subunit%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypoxia-Inducible Factor 1, alpha Subunit/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Glycolysis%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Glycolysis/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Signal+Transduction%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Signal Transduction/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anti-Inflammatory+Agents%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anti-Inflammatory Agents/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anti-Inflammatory+Agents%2ftherapeutic+use%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anti-Inflammatory Agents/therapeutic use</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Models%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Models, Animal</a></li></ul> <a href="javascript:ShowArticleMeSH(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(10);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow11"> <td style="min-width: 40px; text-align: center;"> 11 </td> <td> <div id="citation11" class="article-citation"> <b>Tye H</b>, Conos SA, Djajawi TM, Gottschalk TA, Abdoulkader N, Kong IY, Kammoun HL, Narayana VK, Kratina T, Speir M, Emery J, Simpson DS, Hall C, Vince AJ, Russo S, Crawley R, Rashidi M, Hildebrand JM, Murphy JM, Whitehead L, De Souza DP, Masters SL, Samson AL, Lalaoui N, Hawkins ED, Murphy AJ, Vince JE, Lawlor KE. Divergent roles of RIPK3 and MLKL in high-fat diet-induced obesity and MAFLD in mice. <em class='incite-journal-name' onclick='ShowInCiteJournal(16072);'>Life Sci Alliance</em> 2025;<b>8</b>:e202302446. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39532538' target='_blank'>39532538</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557689' target='_blank'>PMC11557689</a> DOI: <a href='https://dx.doi.org/10.26508/lsa.202302446' target='_blank'>10.26508/lsa.202302446</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.26508/lsa.202302446','39532538', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(11);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(11);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(11);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.26508/lsa.202302446' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(16072);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 10/18/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/16/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv11" value="10.26508/lsa.202302446" /> <div style="display: none" id="articleAbstract11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Cell death frequently occurs in the pathogenesis of obesity and metabolic dysfunction-associated fatty liver disease (MAFLD). However, the exact contribution of core cell death machinery to disease manifestations remains ill-defined. Here, we show via the direct comparison of mice genetically deficient in the essential necroptotic regulators, receptor-interacting protein kinase-3 (RIPK3) and mixed lineage kinase domain-like (MLKL), as well as mice lacking apoptotic caspase-8 in myeloid cells combined with RIPK3 loss, that RIPK3/caspase-8 signaling regulates macrophage inflammatory responses and drives adipose tissue inflammation and MAFLD upon high-fat diet feeding. In contrast, MLKL, divergent to RIPK3, contributes to both obesity and MAFLD in a manner largely independent of inflammation. We also uncover that MLKL regulates the expression of molecules involved in lipid uptake, transport, and metabolism, and congruent with this, we discover a shift in the hepatic lipidome upon MLKL deletion. Collectively, these findings highlight MLKL as an attractive therapeutic target to combat the growing obesity pandemic and metabolic disease. </div> <a href="javascript:ShowArticleAbstract(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <a href="javascript:ShowArticleKeywords(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a 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Inflammation proteomic profiling of psychosis in young adults: Findings from the ALSPAC birth cohort. <em class='incite-journal-name' onclick='ShowInCiteJournal(19918);'>Psychoneuroendocrinology</em> 2025;<b>171</b>:107188. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39442229' target='_blank'>39442229</a> DOI: <a href='https://dx.doi.org/10.1016/j.psyneuen.2024.107188' target='_blank'>10.1016/j.psyneuen.2024.107188</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.psyneuen.2024.107188','39442229', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(12);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(12);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(12);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.psyneuen.2024.107188' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(19918);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.editorialmanager.com/pnec/default.aspx?pg=mainpage.html' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 04/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/12/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/16/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/25/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv12" value="10.1016/j.psyneuen.2024.107188" /> <div style="display: none" id="articleAbstract12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Psychotic disorder is associated with altered levels of various inflammatory markers in blood, but existing studies have typically focused on a few selected biomarkers, have not examined specific symptom domains notably negative symptoms, and are based on individuals with established/chronic illness. Based on data from young people aged 24 years from the Avon Longitudinal Study of Parents and Children (ALSPAC), a UK birth cohort, we have examined the associations of 67 plasma immune/inflammatory proteins assayed using the Olink Target 96 Inflammation panel with psychotic disorder, positive (any psychotic experiences and definite psychotic experiences) and negative symptoms, using linear models with empirical Bayes estimation. The analyses included between 2317 and 2854 individuals. After adjustment for age, sex, body mass index and smoking and correction for multiple testing, positive symptoms and psychotic disorder were consistently associated with upregulation of CDCP1 and IL-6, and psychotic disorder was additionally associated with upregulation of MMP-10. Negative symptoms were associated with upregulation of CDCP1 and TRAIL. CDCP1 and MMP-10 are novel markers of psychosis identified in this study, and are involved in immune regulation, immune cell activation/migration, blood-brain barrier disruption, and extracellular matrix abnormalities. Our findings highlight psychosis symptom domains have overlapping and distinct immune associations, and support a role of inflammation and immune dysfunction in the pathogenesis of psychosis. </div> <a href="javascript:ShowArticleAbstract(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22ALSPAC%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">ALSPAC</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammatory+markers%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammatory markers</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Negative+symptoms%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Negative symptoms</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Positive+symptoms%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Positive symptoms</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Proteomics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Proteomics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Psychosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Psychosis</a></li></ul> <a href="javascript:ShowArticleKeywords(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Psychotic+Disorders%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Psychotic Disorders/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Psychotic+Disorders%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Psychotic Disorders/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Biomarkers%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Biomarkers/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Proteomics%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Proteomics/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Young+Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Young Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Birth+Cohort%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Birth Cohort</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Longitudinal+Studies%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Longitudinal Studies</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22United+Kingdom%2fepidemiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">United Kingdom/epidemiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Interleukin-6%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Interleukin-6/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Interleukin-6%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Interleukin-6/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cohort+Studies%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cohort Studies</a></li></ul> <a href="javascript:ShowArticleMeSH(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(12);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow13"> <td style="min-width: 40px; text-align: center;"> 13 </td> <td> <div id="citation13" class="article-citation"> <b>Shen Y</b>, Nakajima H, Zhu J, Wu W. Integrin β2 regulates titanium particle‑induced inflammation in macrophages: <i>In vitro</i> aseptic loosening model. <em class='incite-journal-name' onclick='ShowInCiteJournal(17029);'>Mol Med Rep</em> 2025;<b>31</b>:25. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39540364' target='_blank'>39540364</a> DOI: <a href='https://dx.doi.org/10.3892/mmr.2024.13390' target='_blank'>10.3892/mmr.2024.13390</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.3892/mmr.2024.13390','39540364', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(13);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(13);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(13);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.3892/mmr.2024.13390' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(17029);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/15/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/27/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/16/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv13" value="10.3892/mmr.2024.13390" /> <div style="display: none" id="articleAbstract13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Aseptic loosening is a major complication of joint replacement surgery, characterized by periprosthetic osteolysis and chronic inflammation at the bone‑implant interface. Cells release chemokines, cytokines and other pro‑inflammatory substances that perpetuate inflammation reactions, while other particle‑stimulated macrophages promote osteoclastic bone resorption and impair bone formation. The present study investigated integrin and inflammatory cytokine expression patterns in RAW 264.7 cells treated with titanium (Ti) particles to elucidate the role of integrins in Ti particle‑mediated inflammatory osteolysis. Assessment was performed by reverse transcription‑quantitative PCR, western blotting, confocal immunofluorescence, flow cytometry and enzyme‑linked immunosorbent assays. Cell migration was evaluated by wound healing assay. It was found that Ti particles significantly induced integrin expression in RAW 264.7 cells, including upregulation of integrins β2 (CD18), aL (CD11a), aM (CD11b) and aX (CD11c). Ti particles also enhanced the expression of Toll‑like receptors (TLRs; TLR1, TLR2, TLR3 and TLR4) and triggered the release of inflammatory cytokines such as tumor necrosis factor α, interleukin (IL)‑1β, IL‑8 and IL‑12. Proteomics showed higher expression and activity levels of TLR2 and TLR4, along with their downstream signaling adaptors myeloid differentiation primary response protein 88 (MyD88) and Mal/TIR‑domain‑containing adapter protein (TIRAP), following Ti treatment. Additionally, Ti treatment significantly enhanced the migration rate of RAW 264.7 cells. The present findings indicated that Ti particles regulate the inflammatory response of RAW 264.7 cells in an in vitro aseptic loosening model by activating the TLR/TIRAP/MyD88 signaling pathway. </div> <a href="javascript:ShowArticleAbstract(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22aseptic+loosening%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">aseptic loosening</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22integrin+%ce%b22%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">integrin β2</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22macrophages%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">macrophages</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22myeloid+differentiation+primary+response+protein+88%2fMal%2fTIR%e2%80%91domain%e2%80%91containing+adapter+protein%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">myeloid differentiation primary response protein 88/Mal/TIR‑domain‑containing adapter protein</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22titanium%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">titanium</a></li></ul> <a href="javascript:ShowArticleKeywords(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Titanium%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Titanium/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RAW+264.7+Cells%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RAW 264.7 Cells</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Macrophages%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Macrophages/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22CD18+Antigens%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">CD18 Antigens/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22CD18+Antigens%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">CD18 Antigens/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cytokines%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cytokines/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Movement%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Movement/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Signal+Transduction%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Signal Transduction/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Osteolysis%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Osteolysis/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Osteolysis%2fchemically+induced%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Osteolysis/chemically induced</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Osteolysis%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Osteolysis/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Osteolysis%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Osteolysis/etiology</a></li><li><a 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href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Prosthesis+Failure%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Prosthesis Failure/adverse effects</a></li></ul> <a href="javascript:ShowArticleMeSH(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(13);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow14"> <td style="min-width: 40px; text-align: center;"> 14 </td> <td> <div id="citation14" class="article-citation"> <b>Ouyang J</b>, Wang H, Gan Y, Huang J. Uric acid mediates kidney tubular inflammation through the LDHA/ROS/NLRP3 pathway. <em class='incite-journal-name' onclick='ShowInCiteJournal(6607);'>Clin Exp Hypertens</em> 2024;<b>46</b>:2424834. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39488824' target='_blank'>39488824</a> DOI: <a href='https://dx.doi.org/10.1080/10641963.2024.2424834' target='_blank'>10.1080/10641963.2024.2424834</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1080/10641963.2024.2424834','39488824', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(14);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(14);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(14);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1080/10641963.2024.2424834' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(6607);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/01/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/26/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/28/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/05/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv14" value="10.1080/10641963.2024.2424834" /> <div style="display: none" id="articleAbstract14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">PURPOSE</div><div class="abstract-content">Hyperuricemia (HUA) is an important factor leading to chronic kidney disease (CKD). The kidney tubular inflammatory response is activated in HUA. This study aimed to investigate whether lactate dehydrogenase A (LDHA) is involved in mediating uric acid-induced kidney tubular inflammatory response. </div><div class="abstract-label">METHODS</div><div class="abstract-content">In vivo, an HUA mouse model was established by continuous intraperitoneal injection of potassium oxonate (PO) for one week. A total of 18 C57BL/6J male adult mice were divided into three groups: control group, HUA group, and HUA+oxamate group, with six mice in each group. Oxamate was intraperitoneally injected into the mice one hour after PO injection. In vitro, an HUA model was simulated by stimulating HK-2 cells with uric acid. Oxamate and tempol inhibited LDHA and reactive oxygen species (ROS) in HK-2 cells. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">In HUA mice, blood uric acid levels were significantly elevated. LDHA in kidney tubular cells was significantly increased in both in vivo and in vitro HUA models, accompanied by an increase in kidney tubular inflammation and ROS. Mechanistically, LDHA mediates uric acid-induced inflammation to kidney tubular cells through the ROS/NLRP3 pathway. Pharmacologic inhibition of LDHA or ROS in kidney tubular cells can significantly ameliorate inflammation response caused by uric acid. </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">LDHA in kidney tubular cells significantly was increased in HUA models. LDHA mediates kidney inflammation response induced by uric acid through the ROS/NLRP3 pathway. This study may provide a new intervention target for preventing kidney tubular inflammation caused by uric acid. </div> <a href="javascript:ShowArticleAbstract(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22LDHA%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">LDHA</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22ROS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">ROS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Uric+acid%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Uric acid</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22inflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">inflammation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22kidney+tubular+cells%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">kidney tubular cells</a></li></ul> <a href="javascript:ShowArticleKeywords(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NLR+Family%2c+Pyrin+Domain-Containing+3+Protein%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">NLR Family, Pyrin Domain-Containing 3 Protein/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Uric+Acid%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Uric Acid/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Uric+Acid%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Uric Acid/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reactive+Oxygen+Species%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reactive Oxygen Species/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hyperuricemia%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hyperuricemia/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%2c+Inbred+C57BL%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice, Inbred C57BL</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Kidney+Tubules%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Kidney Tubules/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Kidney+Tubules%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Kidney Tubules/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Signal+Transduction%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Signal Transduction</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Line%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Line</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Models%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Models, Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Lactate+Dehydrogenase+5%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Lactate Dehydrogenase 5/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cyclic+N-Oxides%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cyclic N-Oxides/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22L-Lactate+Dehydrogenase%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">L-Lactate Dehydrogenase/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Spin+Labels%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Spin Labels</a></li></ul> <a href="javascript:ShowArticleMeSH(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(14);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow15"> <td style="min-width: 40px; text-align: center;"> 15 </td> <td> <div id="citation15" class="article-citation"> <b>Bai L</b>, Gao Y, Li L, Liang Z, Qiao Y, Wang X, Yv L, Yang JJ, Xu JT. Poly-(ADP-ribose) polymerase 1-modulated production of CXCL1 in the dorsal root ganglion and spinal dorsal horn exacerbated inflammatory pain in rats. <em class='incite-journal-name' onclick='ShowInCiteJournal(11367);'>Int Immunopharmacol</em> 2024;<b>143</b>:113370. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39405941' target='_blank'>39405941</a> DOI: <a href='https://dx.doi.org/10.1016/j.intimp.2024.113370' target='_blank'>10.1016/j.intimp.2024.113370</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.intimp.2024.113370','39405941', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(15);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(15);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(15);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.intimp.2024.113370' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(11367);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/09/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/03/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/07/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/30/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv15" value="10.1016/j.intimp.2024.113370" /> <div style="display: none" id="articleAbstract15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Poly (ADP-ribose) polymerase 1 (PARP-1) serves as a transcriptional co-regulator and has been playing an important role in various inflammatory diseases. In the present study, we investigated the role and underlying mechanisms of action of PARP-1 in inflammatory pain. Intraplantar injection of complete Freund's adjuvant (CFA) was administered to the rats to induce inflammatory pain. Immunofluorescence, Western blotting, co-immunoprecipitation, and chromatin immunoprecipitation-quantitative polymerase chain reaction were performed to investigate the underlying mechanisms. Our results showed that CFA injection led to an increase in the production and activation of PARP-1 in both the L4/5 dorsal root ganglions (DRGs) and the spinal dorsal horn. Repeated intrathecal injections of Tiq-A or 5-AIQ, two specific inhibitors of PARP-1, and microinjections of AAV-PARP-1 shRNA into the L5 DRG or L5 spinal dorsal horn partially prevented the development of inflammatory pain. The established inflammatory pain was attenuated by a single bolus of intrathecal injection of Tiq-A or 5-AIQ on day 7 after the CFA injection. The CFA-induced mechanical allodynia and thermal hyperalgesia in female rats were alleviated by repeated intrathecal injections of Tiq-A. Moreover, repeated intrathecal injections of 5-AIQ inhibited the binding of NF-κB with CXCL1 promoter and reduced the production of CXCL1 in both the L4/5 DRGs and L4-6 spinal dorsal horns following CFA injection. Collectively, our results indicate that CFA-induced upregulation of PARP-1 by promoting CXCL1 expression in the DRG and probably in the spinal dorsal horn contributes to the pathogenesis of inflammatory pain. Thus, PARP-1 may be a potential pharmaceutical target for the treatment of inflammatory pain. </div> <a href="javascript:ShowArticleAbstract(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22CXCL1%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">CXCL1</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dorsal+root+ganglion%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dorsal root ganglion</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Epigenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Epigenetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammatory+pain%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammatory pain</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Poly-(ADP-ribose)+polymerase+1%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Poly-(ADP-ribose) polymerase 1</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Spinal+cord%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Spinal cord</a></li></ul> <a href="javascript:ShowArticleKeywords(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chemokine+CXCL1%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chemokine CXCL1/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chemokine+CXCL1%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chemokine CXCL1/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Freund%27s+Adjuvant%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Freund's Adjuvant</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ganglia%2c+Spinal%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ganglia, Spinal/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hyperalgesia%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hyperalgesia/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pain%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pain/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Poly+(ADP-Ribose)+Polymerase-1%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Poly (ADP-Ribose) Polymerase-1/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Poly+(ADP-Ribose)+Polymerase-1%2fantagonists+%26amp%3b+inhibitors%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Poly (ADP-Ribose) Polymerase-1/antagonists & inhibitors</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Poly+(ADP-Ribose)+Polymerase-1%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Poly (ADP-Ribose) Polymerase-1/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Poly(ADP-ribose)+Polymerase+Inhibitors%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Poly(ADP-ribose) Polymerase Inhibitors/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Spinal+Cord+Dorsal+Horn%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Spinal Cord Dorsal Horn/metabolism</a></li></ul> <a href="javascript:ShowArticleMeSH(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(15);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow16"> <td style="min-width: 40px; text-align: center;"> 16 </td> <td> <div id="citation16" class="article-citation"> <b>Zhao X</b>, Hu X, Wang W, Lu S. Macrophages dying from ferroptosis promote microglia-mediated inflammatory responses during spinal cord injury. <em class='incite-journal-name' onclick='ShowInCiteJournal(11367);'>Int Immunopharmacol</em> 2024;<b>143</b>:113281. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39357207' target='_blank'>39357207</a> DOI: <a href='https://dx.doi.org/10.1016/j.intimp.2024.113281' target='_blank'>10.1016/j.intimp.2024.113281</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.intimp.2024.113281','39357207', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(16);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(16);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(16);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.intimp.2024.113281' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(11367);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/01/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/15/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/26/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/04/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv16" value="10.1016/j.intimp.2024.113281" /> <div style="display: none" id="articleAbstract16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">The neurological deficits following traumatic spinal cord injury are associated with severe patient disability and economic consequences. Currently, an increasing number of studies are focusing on the importance of ferroptosis during acute organ injuries. However, the spatial and temporal distribution patterns of ferroptosis during SCI and the details of its role are largely unknown. In this study, in vivo experiments revealed that microglia are in close proximity to macrophages, the major cell type that undergoes ferroptosis following SCI. Furthermore, we found that ferroptotic macrophages aggravate SCI by inducing the proinflammatory properties of microglia. In vitro studies further revealed ferroptotic macrophages increased the expression of IL-1β, IL-6, and IL-23 in microglia. Mechanistically, due to the activation of the NF-κB signaling pathway, the expression of IL-1β and IL-6 was increased. In addition, we established that increased levels of oxidative phosphorylation cause mitochondrial reactive oxygen species generation and unfolded protein response activation and trigger an inflammatory response marked by an increase in IL-23 production. Our findings identified that targeting ferroptosis and IL-23 could be an effective strategy for promoting neurological recovery after SCI. </div> <a href="javascript:ShowArticleAbstract(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ferroptotic+macrophage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ferroptotic macrophage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Microglia%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Microglia</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuroinflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuroinflammation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pathogenic+Th17+cell%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pathogenic Th17 cell</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Spinal+cord+injury%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Spinal cord injury</a></li></ul> <a href="javascript:ShowArticleKeywords(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Spinal+Cord+Injuries%2fimmunology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Spinal Cord Injuries/immunology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Spinal+Cord+Injuries%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Spinal Cord Injuries/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Spinal+Cord+Injuries%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Spinal Cord Injuries/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ferroptosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ferroptosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Microglia%2fimmunology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Microglia/immunology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Microglia%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Microglia/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Macrophages%2fimmunology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Macrophages/immunology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Macrophages%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Macrophages/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%2c+Inbred+C57BL%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice, Inbred C57BL</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reactive+Oxygen+Species%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reactive Oxygen Species/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fimmunology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/immunology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NF-kappa+B%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">NF-kappa B/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Signal+Transduction%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Signal Transduction</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Interleukin-23%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Interleukin-23/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Models%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Models, Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li></ul> <a href="javascript:ShowArticleMeSH(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(16);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow17"> <td style="min-width: 40px; text-align: center;"> 17 </td> <td> <div id="citation17" class="article-citation"> <b>Weng L</b>, Zhu Q, Xiang Y, Cao T, Cai J, Liang N, Hong X, Xue M, Ge H. METTL3-mediated m<sup>6</sup>A modification of CD36: Implications for glucose metabolism and inflammatory dysregulation in follicles of polycystic ovary syndrome. <em class='incite-journal-name' onclick='ShowInCiteJournal(11367);'>Int Immunopharmacol</em> 2024;<b>143</b>:113327. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39395382' target='_blank'>39395382</a> DOI: <a href='https://dx.doi.org/10.1016/j.intimp.2024.113327' target='_blank'>10.1016/j.intimp.2024.113327</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.intimp.2024.113327','39395382', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(17);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(17);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(17);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.intimp.2024.113327' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(11367);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/06/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/16/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/02/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/14/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv17" value="10.1016/j.intimp.2024.113327" /> <div style="display: none" id="articleAbstract17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder that affects women of reproductive age and is characterized by menstrual irregularities, metabolic imbalances and infertility. The pathogenesis of PCOS is complex and not fully understood, and chronic inflammation and insulin resistance are implicated in its progression. In this study, we investigated the role of m6A methylation, an important epigenetic modification, in the pathogenesis of PCOS. Using methylated RNA immunoprecipitation sequencing (MeRIP-seq) and RNA sequencing (RNA-seq), we mapped the m6A methylation profile in granulosa cells from patients with PCOS and identified a significant regulatory effect on gene expression. CD36 is a novel m6A-regulated gene that may facilitate the progression of PCOS. We demonstrated that METTL3, an m6A methyltransferase, modulated CD36 expression and influenced glucose metabolism and inflammatory responses in PCOS. Employing KGN cells as a model of insulin resistance, we observed that CD36 knockdown ameliorated the impaired glucose uptake and significantly reduced the production of pro-inflammatory cytokines. These findings are consistent with the results of CD36 inhibition in a mouse model of PCOS, indicating a role of CD36 in modulating the disease phenotype. Our study delineates a previously unrecognized epigenetic mechanism involving m6A methylation in PCOS, highlighting the potential of targeting the METTL3-CD36 axis as a therapeutic strategy for managing ovarian inflammation and metabolic dysregulation in patients with PCOS. </div> <a href="javascript:ShowArticleAbstract(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22CD36%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">CD36</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Insulin+resistance%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Insulin resistance</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22METTL3%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">METTL3</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Polycystic+ovary+syndrome%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Polycystic ovary syndrome</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22m(6)A+methylation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">m(6)A methylation</a></li></ul> <a href="javascript:ShowArticleKeywords(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Polycystic+Ovary+Syndrome%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Polycystic Ovary Syndrome/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Polycystic+Ovary+Syndrome%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Polycystic Ovary Syndrome/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Polycystic+Ovary+Syndrome%2fimmunology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Polycystic Ovary Syndrome/immunology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Methyltransferases%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Methyltransferases/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Methyltransferases%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Methyltransferases/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22CD36+Antigens%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">CD36 Antigens/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22CD36+Antigens%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">CD36 Antigens/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Glucose%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Glucose/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ovarian+Follicle%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ovarian Follicle/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/metabolism</a></li><li><a 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href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Methylation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Methylation</a></li></ul> <a href="javascript:ShowArticleMeSH(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(17);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow18"> <td style="min-width: 40px; text-align: center;"> 18 </td> <td> <div id="citation18" class="article-citation"> <b>Sun J</b>, Li Y, Meng M, Zeng X, Wang Q, Li W, Luo Y, Chen H, Dong Q. SIRT7 inhibits the aging and inflammatory damage of hPDLFs by suppressing the AKT/mTOR. <em class='incite-journal-name' onclick='ShowInCiteJournal(11367);'>Int Immunopharmacol</em> 2024;<b>143</b>:113300. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39378651' target='_blank'>39378651</a> DOI: <a href='https://dx.doi.org/10.1016/j.intimp.2024.113300' target='_blank'>10.1016/j.intimp.2024.113300</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.intimp.2024.113300','39378651', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(18);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(18);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(18);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.intimp.2024.113300' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(11367);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/21/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/22/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/10/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv18" value="10.1016/j.intimp.2024.113300" /> <div style="display: none" id="articleAbstract18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Periodontitis seriously affects oral health worldwide. Despite extensive efforts in prevention and treatment methods over the years, the prevalence of periodontitis in the population has not decreased. DNA damage-induced cellular senescence may be one of the mechanisms underlying periodontitis.Sirtuin7 (SIRT7) has deacetylase activity and regulates a variety of biological processes, including cell proliferation, death, and DNA damage repair.Increasing evidence confirms the crucial role of SIRT7 in age-related and inflammatory diseases. However, the mechanism of action of SIRT7 in periodontitis remains unclear. Our study demonstrates that SIRT7 is downregulated in human periodontal ligament fibroblasts induced by Porphyromonas gingivalis lipopolysaccharide (Pg-LPS). Overexpression of the SIRT7 gene significantly reduces the production of senescence-related molecules P53, P21, P16, as well as inflammatory cytokines IL-1β and TNF-α stimulated by Pg-LPS. Furthermore, overexpression of the SIRT7 gene significantly decreases the phosphorylation levels of AKT and mTOR in Pg-LPS-treated hPDLFs. Conversely, SIRT7 gene knockdown exhibits opposite effects compared to overexpression in Pg-LPS-treated hPDLFs. In conclusion, our findings indicate that SIRT7 can inhibit Pg-LPS-induced senescence and consequently suppress the secretion of inflammatory cytokines through the AKT/mTOR pathway. As a result, SIRT7 could be regarded a viable pharmaceutical target for clinical periodontitis treatment. </div> <a href="javascript:ShowArticleAbstract(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22AKT%2fmTOR+pathway%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">AKT/mTOR pathway</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+senescence%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell senescence</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Periodontitis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Periodontitis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22SIRT7%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">SIRT7</a></li></ul> <a href="javascript:ShowArticleKeywords(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22TOR+Serine-Threonine+Kinases%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">TOR Serine-Threonine Kinases/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sirtuins%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sirtuins/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sirtuins%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sirtuins/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Proto-Oncogene+Proteins+c-akt%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Proto-Oncogene Proteins c-akt/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cellular+Senescence%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cellular Senescence</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Periodontitis%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Periodontitis/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Periodontitis%2fimmunology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Periodontitis/immunology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Lipopolysaccharides%2fimmunology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Lipopolysaccharides/immunology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Fibroblasts%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Fibroblasts/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cells%2c+Cultured%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cells, Cultured</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Periodontal+Ligament%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Periodontal Ligament/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Periodontal+Ligament%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Periodontal Ligament/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Signal+Transduction%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Signal Transduction</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Porphyromonas+gingivalis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Porphyromonas gingivalis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cytokines%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cytokines/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aging</a></li></ul> <a href="javascript:ShowArticleMeSH(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(18);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow19"> <td style="min-width: 40px; text-align: center;"> 19 </td> <td> <div id="citation19" class="article-citation"> <b>Song QX</b>, Zhang YY, Li YL, Liu F, Liu YJ, Li YK, Li CJ, Zhou C, Shen JF. The crucial role of NR2A mediating the activation of satellite glial cells in the trigeminal ganglion contributes to orofacial inflammatory pain during TMJ inflammation. <em class='incite-journal-name' onclick='ShowInCiteJournal(17736);'>Neuropharmacology</em> 2024;<b>261</b>:110173. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39357737' target='_blank'>39357737</a> DOI: <a href='https://dx.doi.org/10.1016/j.neuropharm.2024.110173' target='_blank'>10.1016/j.neuropharm.2024.110173</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.neuropharm.2024.110173','39357737', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(19);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(19);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(19);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.neuropharm.2024.110173' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(17736);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/10/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/31/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/27/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/04/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv19" value="10.1016/j.neuropharm.2024.110173" /> <div style="display: none" id="articleAbstract19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Temporomandibular joint inflammatory diseases are a significant subtype of temporomandibular disorders (TMD) characterized by inflammatory pain in the orofacial area. The N-methyl-D-aspartate receptor (NMDAR), specifically the NR2A subtype, was crucial in neuropathic pain. However, the exact role of NR2A in inflammatory pain in the TMJ and the molecular and cellular mechanisms mediating peripheral sensitization in the trigeminal ganglion (TG) remain unclear. This study utilized male and female mice to induce the TMJOA model by injecting Complete Freund's adjuvant (CFA) into the TMJ and achieve conditional knockout (CKO) of NR2A in the TG using Cre/Loxp technology. The Von-Frey filament test results showed that CFA-induced orofacial pain with reduced mechanical withdrawal threshold (MWT), which was not developed in NR2A CKO mice. Additionally, the up-regulation of interleukin (IL)-1β, IL-6, and nerve growth factor (NGF) in the TG induced by CFA did not occur by NR2A deficiency. In vitro, NMDA activated satellite glial cells (SGCs) with high expression of glial fibrillary acidic protein (GFAP), and both NMDA and LPS led to increased IL-1β, IL-6, and NGF in SGCs. NR2A deficiency reduced these stimulating effects of NMDA and LPS. The regulation of IL-1β involved the p38, Protein Kinase A (PKA), and Protein Kinase C (PKC) pathways, while IL-6 signaling relied on PKA and PKC pathways. NGF regulation was primarily through the p38 pathway. This study highlighted NR2A's crucial role in the TG peripheral sensitization during TMJ inflammation by mediating ILs and NGF, suggesting potential targets for orofacial inflammatory pain management. </div> <a href="javascript:ShowArticleAbstract(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Interleukins%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Interleukins</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NR2A%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">NR2A</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nerve+growth+factor%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nerve growth factor</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Orofacial+inflammatory+pain%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Orofacial inflammatory pain</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22SGCs+activation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">SGCs activation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Temporomandibular+joint+inflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Temporomandibular joint inflammation</a></li></ul> <a href="javascript:ShowArticleKeywords(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Facial+Pain%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Facial Pain/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Freund%27s+Adjuvant%2ftoxicity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Freund's Adjuvant/toxicity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%2c+Inbred+C57BL%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice, Inbred C57BL</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%2c+Knockout%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice, Knockout</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuroglia%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuroglia/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Receptors%2c+N-Methyl-D-Aspartate%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Receptors, N-Methyl-D-Aspartate/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Satellite+Cells%2c+Perineuronal%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Satellite Cells, Perineuronal/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Temporomandibular+Joint+Disorders%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Temporomandibular Joint Disorders/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Trigeminal+Ganglion%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Trigeminal Ganglion/metabolism</a></li></ul> <a href="javascript:ShowArticleMeSH(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(19);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow20"> <td style="min-width: 40px; text-align: center;"> 20 </td> <td> <div id="citation20" class="article-citation"> <b>Ren K</b>, Dai L, Zhang H, He Y, Liu B, Hu Y, Ma K, Tian W, Zhao D. Neuritin attenuates neuroinflammation and apoptosis in early brain injury after subarachnoid hemorrhage via endoplasmic reticulum stress-related inflammatory pathways. <em class='incite-journal-name' onclick='ShowInCiteJournal(4013);'>Brain Res</em> 2024;<b>1845</b>:149293. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39454807' target='_blank'>39454807</a> DOI: <a href='https://dx.doi.org/10.1016/j.brainres.2024.149293' target='_blank'>10.1016/j.brainres.2024.149293</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.brainres.2024.149293','39454807', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(20);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(20);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(20);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.brainres.2024.149293' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(4013);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/12/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/11/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/22/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/28/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv20" value="10.1016/j.brainres.2024.149293" /> <div style="display: none" id="articleAbstract20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Neuroinflammation is a key destructive pathophysiological process in early brain injury (EBI) following subarachnoid hemorrhage (SAH). Recent studies have discovered that endoplasmic reticulum stress-related inflammatory pathways include the IRE1α-TRAF2-NF-κB pathway, PERK-eIF2α-NF-κB pathway, and ATF6-AKT -NF-κB pathway leading to neuroinflammatory response. Neuritin is a neurotrophin that is involved in neuronal plasticity and regeneration. Studies have suggested that Neuritin has a vital role in reducing neuroinflammation, and can also decrease the expression of proteins related to endoplasmic reticulum stress following SAH. This suggests that Neuritin could be a potential therapeutic target for SAH and other neurological conditions. However, the regulatory mechanisms of Neuritin in ER stress-related inflammatory pathways after SAH are not yet fully understood. In this work, we discovered that the activation of ER stress-related inflammatory pathways leads to neuroinflammation, which further aggravates neuronal apoptosis after SAH. Our findings indicate that Neuritin overexpression play a neuroprotective role by inhibiting IRE1α-TRAF2-NF-κB pathway, PERK-eIF2α-NF-κB pathway, and ATF6-AKT-NF-κB pathway associated with endoplasmic reticulum stress. These inhibitory effects on neuroinflammation ultimately reduce nerve cell apoptosis. </div> <a href="javascript:ShowArticleAbstract(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Apoptosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Apoptosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Endoplasmic+reticulum+stress%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Endoplasmic reticulum stress</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuritin%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuritin</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuroinflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuroinflammation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Subarachnoid+hemorrhage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Subarachnoid hemorrhage</a></li></ul> <a href="javascript:ShowArticleKeywords(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Subarachnoid+Hemorrhage%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Subarachnoid Hemorrhage/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Subarachnoid+Hemorrhage%2fcomplications%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Subarachnoid Hemorrhage/complications</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Endoplasmic+Reticulum+Stress%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Endoplasmic Reticulum Stress/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Endoplasmic+Reticulum+Stress%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Endoplasmic Reticulum Stress/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Apoptosis%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Apoptosis/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Apoptosis%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Apoptosis/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuropeptides%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuropeptides/metabolism</a></li><li><a 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href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nerve+Growth+Factors%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nerve Growth Factors/metabolism</a></li></ul> <a href="javascript:ShowArticleMeSH(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(20);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow21"> <td style="min-width: 40px; text-align: center;"> 21 </td> <td> <div id="citation21" class="article-citation"> <b>Chen J</b>, Cai Y, Wei D, Cao L, He Q, Zhang Y. Formononetin inhibits neuroinflammation in BV2 microglia induced by glucose and oxygen deprivation reperfusion through TLR4/NF-κB signaling pathway. <em class='incite-journal-name' onclick='ShowInCiteJournal(4013);'>Brain Res</em> 2024;<b>1845</b>:149218. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39218334' target='_blank'>39218334</a> DOI: <a href='https://dx.doi.org/10.1016/j.brainres.2024.149218' target='_blank'>10.1016/j.brainres.2024.149218</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.brainres.2024.149218','39218334', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(21);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(21);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(21);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.brainres.2024.149218' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(4013);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/19/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/04/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv21" value="10.1016/j.brainres.2024.149218" /> <div style="display: none" id="articleAbstract21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Ischemic stroke, caused by diminished or interrupted cerebral blood flow, triggers the activation of microglial cells and subsequent inflammatory responses. Formononetin (FMN) has been observed to inhibit BV2 microglial cell activation and alleviate ensuing neuroinflammatory reactions. Despite extensive research, the precise underlying mechanism remains unclear. To investigate the neuroinflammatory response following FMN-mediated inhibition of BV2 microglial activation, we employed an in vitro oxygen-glucose deprivation/reperfusion (OGD/R) model. BV2 microglial cells were categorized into four groups: control, FMN, OGD/R, and OGD/R+FMN. Cell viability was assessed using the CCK-8 assay, while flow cytometry assessed M1 and M2 cell populations within BV2 cells. Immunofluorescence was utilized to detect the expression levels of apoptosis-inducing factor (AIF), p53, Toll-like receptor 4 (TLR4), and NF-κB p65. Western blotting (WB) was conducted to quantify p65/p-p65, IκB-α/p-IκB-α, and TLR4 protein levels in each group. Additionally, ELISA was employed to measure IL-1β and TNF-α levels in cell supernatants from each group. The results revealed a significant increase in the proportion of iNOS/CD206-positive M1/M2 cells in the OGD/R group compared to the control group (p < 0.05). There was also a notable increase in nuclear translocation of NF-κB p65 and elevated expression of inflammatory factors IL-1β and TNF-α in cell supernatants. Moreover, levels of p-p65, p-IκB-α, and TLR4 proteins were significantly elevated in the OGD/R group (p < 0.05). However, the addition of FMN reversed these effects. Specifically, FMN administration notably attenuated cell death and inflammation in BV2 microglia induced by OGD/R through modulation of the TLR4/NF-κB signaling pathway.These findings suggest that FMN may serve as a potential therapeutic agent against neuroinflammation associated with ischemic stroke by targeting microglial activation pathways. </div> <a href="javascript:ShowArticleAbstract(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Formononetin%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Formononetin</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Microglia+polarization%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Microglia polarization</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuroinflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuroinflammation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22oxygen-glucose+deprivation+reperfusion+(OGD%2fR)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">oxygen-glucose deprivation reperfusion (OGD/R)</a></li></ul> <a href="javascript:ShowArticleKeywords(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Isoflavones%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Isoflavones/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Microglia%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Microglia/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Microglia%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Microglia/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Toll-Like+Receptor+4%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Toll-Like Receptor 4/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Glucose%2fdeficiency%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Glucose/deficiency</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Glucose%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Glucose/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Signal+Transduction%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Signal Transduction/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Signal+Transduction%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Signal Transduction/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NF-kappa+B%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">NF-kappa B/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuroinflammatory+Diseases%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuroinflammatory Diseases/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuroinflammatory+Diseases%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuroinflammatory Diseases/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Line%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Line</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Oxygen%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Oxygen/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Survival%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Survival/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Survival%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Survival/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/drug therapy</a></li></ul> <a href="javascript:ShowArticleMeSH(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(21);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow22"> <td style="min-width: 40px; text-align: center;"> 22 </td> <td> <div id="citation22" class="article-citation"> <b>Li X</b>, Hu C, Luo S, Dai F, Li C, Zhou W, Wang J, Chen H, Wang Z, Long T, Jiang L, Tang C. Cav3.2 deletion attenuates nonalcoholic fatty liver disease in mice. <em class='incite-journal-name' onclick='ShowInCiteJournal(9624);'>Gene</em> 2024;<b>929</b>:148812. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39116959' target='_blank'>39116959</a> DOI: <a href='https://dx.doi.org/10.1016/j.gene.2024.148812' target='_blank'>10.1016/j.gene.2024.148812</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.gene.2024.148812','39116959', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(22);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(22);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(22);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.gene.2024.148812' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(9624);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 03/16/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/11/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 07/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 08/10/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv22" value="10.1016/j.gene.2024.148812" /> <div style="display: none" id="articleAbstract22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and represents the main cause of liver cirrhosis and hepatocellular carcinoma. Cav3.2 is a T-type calcium channel that is widely present in tissues throughout the body and plays a vital role in energy and metabolic balance. However, the effects of Cav3.2 on the NFALD remain unclear. Here, we investigated the role of Cav3.2 channel in the development and progression of NAFLD. After 16 weeks on a high-fat diets (HFD), Cav3.2 knockout (Cav3.2 KO) improved hepatic steatosis, liver injury and metabolic syndrome in an NAFLD mouse model. We provided evidence that Cav3.2 KO inhibited HFD-induced hepatic oxidative stress, inflammation and hepatocyte apoptosis. In addition, Cav3.2 KO also attenuated hepatic lipid accumulation, oxidative stress, inflammation and hepatocyte apoptosis in palmitic acid/oleic acid (PAOA)-treated primary hepatocytes. These results suggest that therapeutic approaches targeting Cav3.2 provide effective approaches for treating NAFLD. </div> <a href="javascript:ShowArticleAbstract(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cav3.2%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cav3.2</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nonalcoholic+fatty+liver+disease%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nonalcoholic fatty liver disease</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Oxidative+stress%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Oxidative stress</a></li></ul> <a href="javascript:ShowArticleKeywords(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Non-alcoholic+Fatty+Liver+Disease%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Non-alcoholic Fatty Liver Disease/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Non-alcoholic+Fatty+Liver+Disease%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Non-alcoholic Fatty Liver Disease/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Non-alcoholic+Fatty+Liver+Disease%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Non-alcoholic Fatty Liver Disease/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Calcium+Channels%2c+T-Type%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Calcium Channels, T-Type/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Calcium+Channels%2c+T-Type%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Calcium Channels, T-Type/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diet%2c+High-Fat%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diet, High-Fat/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Oxidative+Stress%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Oxidative Stress</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hepatocytes%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hepatocytes/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hepatocytes%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hepatocytes/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%2c+Knockout%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice, Knockout</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Apoptosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Apoptosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%2c+Inbred+C57BL%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice, Inbred C57BL</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Models%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Models, Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Liver%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Liver/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Liver%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Liver/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/metabolism</a></li></ul> <a href="javascript:ShowArticleMeSH(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(22);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow23"> <td style="min-width: 40px; text-align: center;"> 23 </td> <td> <div id="citation23" class="article-citation"> <b>Cheng K</b>, Liu K, Liu S, Zhao Y, Wang Q. IGF2BP3 regulates macrophage-induced inflammation and liver damage in acute-on-chronic liver failure via the RORα-NF-κB signaling axis. <em class='incite-journal-name' onclick='ShowInCiteJournal(11367);'>Int Immunopharmacol</em> 2024;<b>142</b>:113030. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39232362' target='_blank'>39232362</a> DOI: <a href='https://dx.doi.org/10.1016/j.intimp.2024.113030' target='_blank'>10.1016/j.intimp.2024.113030</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.intimp.2024.113030','39232362', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(23);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(23);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(23);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.intimp.2024.113030' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(11367);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/31/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/23/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/25/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/06/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv23" value="10.1016/j.intimp.2024.113030" /> <div style="display: none" id="articleAbstract23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Acute-on-chronic liver failure (ACLF) is a severe condition characterized by high mortality rates, and macrophage-mediated inflammation plays a critical role in its progression. Our previous research has indicated the involvement of the RNA-binding protein IGF2BP3 in the pathogenesis of ACLF. However, the underlying molecular mechanisms contributing to this damage require further elucidation. Initially, we observed heightened expression of pro-inflammatory cytokines and macrophage activation in both ACLF patients and a mouse model induced by D-GalN/LPS. Subsequent loss-of-function experiments targeting IGF2BP3 revealed that the knockdown of IGF2BP3 potentially confers hepatoprotection by mitigating macrophage-induced inflammation. Further investigation using RNA Immunoprecipitation (RIP) assays and dual luciferase reporter assays confirmed that RORα is a target protein of the RNA-binding protein IGF2BP3. Importantly, depletion of RORα was found to significantly increase liver damage and inflammation by modulating the NF-κB signaling pathway. In conclusion, our findings underscore the crucial role of IGF2BP3 in mediating liver damage induced by activated macrophages in ACLF, which is regulated by the RORα-NF-κB signaling pathway. These discoveries offer novel insights into the pathogenesis and potential therapeutic targets for ACLF. </div> <a href="javascript:ShowArticleAbstract(23);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Acute-on-chronic+liver+failure%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Acute-on-chronic liver failure</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22IGF2BP3%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">IGF2BP3</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Macrophage+activation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Macrophage activation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NF-%ce%baB+signaling%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">NF-κB signaling</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22ROR%ce%b1%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RORα</a></li></ul> <a href="javascript:ShowArticleKeywords(23);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Acute-On-Chronic+Liver+Failure%2fimmunology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Acute-On-Chronic Liver Failure/immunology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Acute-On-Chronic+Liver+Failure%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Acute-On-Chronic Liver Failure/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cytokines%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" 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href="javascript:ShowArticleGrant(23);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow24"> <td style="min-width: 40px; text-align: center;"> 24 </td> <td> <div id="citation24" class="article-citation"> <b>Sun Y</b>, Zhu D, Kong L, Du W, Qu L, Yang Y, Rao G, Huang F, Tong X. Vasicine attenuates atherosclerosis via lipid regulation, inflammation inhibition, and autophagy activation in ApoE<sup>-/-</sup> mice. <em class='incite-journal-name' onclick='ShowInCiteJournal(11367);'>Int Immunopharmacol</em> 2024;<b>142</b>:112996. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39243558' target='_blank'>39243558</a> DOI: <a href='https://dx.doi.org/10.1016/j.intimp.2024.112996' target='_blank'>10.1016/j.intimp.2024.112996</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.intimp.2024.112996','39243558', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(24);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(24);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(24);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.intimp.2024.112996' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(11367);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 02/26/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/18/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/19/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/09/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv24" value="10.1016/j.intimp.2024.112996" /> <div style="display: none" id="articleAbstract24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Atherosclerosis is marked with the accumulation of low-density lipoproteins and chronic inflammation. The anti-inflammatory therapies exert protective effects on atherosclerosis. Vasicine is a bioactive alkaloid with anti-inflammatory activity from a medicinal plant in Ayurveda and Unani. In this study, the effects of vasicine were evaluated on atherosclerosis in vivo and in vitro. The results showed that vasicine alleviated atherosclerotic lesions and regulated the lipid synthesis by reducing the levels of TC, TG, LDL-C and inhibiting the expresses of scavenger receptors (SR-A, CD36 and LOX-1) to inhibit foam cell formations. And vasicine decreased the levels of IL-1β, IL-6, MCP-1, and TNF-α to modulate inflammatory response. Besides, vasicine downregulated MAPK and PI3K/AKT/mTOR pathway to activated autophagy, which inhibited the procession of atherosclerosis. </div> <a href="javascript:ShowArticleAbstract(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Apolipoprotein-E-deficient+mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Apolipoprotein-E-deficient mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Atherosclerosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Atherosclerosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Autophagy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Autophagy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Vasicine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Vasicine</a></li></ul> <a href="javascript:ShowArticleKeywords(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a 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href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Alkaloids%2ftherapeutic+use%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Alkaloids/therapeutic use</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Signal+Transduction%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Signal Transduction/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Foam+Cells%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Foam Cells/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Foam+Cells%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Foam Cells/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%2c+Knockout%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice, Knockout</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RAW+264.7+Cells%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RAW 264.7 Cells</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Models%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Models, Animal</a></li></ul> <a href="javascript:ShowArticleMeSH(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(24);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow25"> <td style="min-width: 40px; text-align: center;"> 25 </td> <td> <div id="citation25" class="article-citation"> <b>Ali DE</b>, El-Shiekh RA, El Sawy MA, Khalifa AA, Elblehi SS, Elsokkary NH, Ali MA. In vivo anti-gastric ulcer activity of 7-O-methyl aromadendrin and sakuranetin via mitigating inflammatory and oxidative stress trails. <em>JOURNAL OF ETHNOPHARMACOLOGY</em> 2024;<b>335</b>:118617. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39053715' target='_blank'>39053715</a> DOI: <a href='https://dx.doi.org/10.1016/j.jep.2024.118617' target='_blank'>10.1016/j.jep.2024.118617</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.jep.2024.118617','39053715', 'Inflammation/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(25);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(25);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(25);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.jep.2024.118617' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 03/23/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/10/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 07/22/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 07/27/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv25" value="10.1016/j.jep.2024.118617" /> <div style="display: none" id="articleAbstract25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">ETHNOPHARMACOLOGICAL RELEVANCE</div><div class="abstract-content">Eucalyptus genus has been used for a very long time in conventional treatment as an anti-ulcer remedy. </div><div class="abstract-label">AIM OF THE STUDY</div><div class="abstract-content">The study aimed to explore the gastroprotective potential of 7-O-methyl aromadendrin (7-OMA), and sakuranetin (SKN) in comparison with omeprazole. The study tackled the contribution of their anti-inflammatory, antioxidant, and antiapoptotic capabilities to their anti-gastric ulcer effects. </div><div class="abstract-label">MATERIALS AND METHODS</div><div class="abstract-content">An ethanol-induced gastric ulcer model in rats was adopted and the consequences were confirmed by a molecular docking study. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">The oral pretreatment of rats 1 h before ethanol using omeprazole (20 mg/kg) or 7-OMA (20 or 40 mg/kg) or SKN (20 or 40 mg/kg) exhibited gastroprotective and anti-inflammatory properties to different extents. These amendments witnessed as restorations in the stomach histological architecture in H and E-stained sections, mucus content in periodic acid-Schiff (PAS) stained sections with increased cellular proliferation, as demonstrated by increased immunohistochemical staining of PCNA, and increments in stomach COX-1 activity and eNOS. The highest dose of SKN showed the best corrections to reach 4.8, 1.8, and 2.1 folds increase in PAS, COX-1 and eNOS, respectively as compared to the untreated ethanol-induced gastric ulcer group; effects that were comparable to that of omeprazole. Moreover, reductions in COX-2 activity, and the protein expression of NF-κB, IL-6, TNF-α and NOx, in addition to the gene expression of inducible iNOS were also noted. Moreover, the antioxidant and antiapoptotic capabilities of omeprazole, 7-OMA, and SKN were perceived. SKN (40 mg/kg) succeeded to show the unsurpassed results to reach 293.6%, 237.1%, 274.7%, 248.2%, and 175.4% in total and reduced GSH, catalase, SOD, and Bcl2, respectively, as well as 50.0%, 46.8%, and 52.1 % in oxidized GSSG, TBARS and caspase-3, respectively. The gastroprotective potential of the tested compounds can be assigned to their anti-inflammatory, antioxidant and antiapoptotic properties.7-OMA and SKN were studied using molecular docking into the binding sites of the most significant inflammatory targets, including COX-2, TNF-α, iNOS, and NF-κB. Pharmacokinetic and physicochemical parameters in silico were appropriate. </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">The prophylactic use of 7-OMA and SKN could be considered as an add-on to recurrent gastric ulcers and might influence its therapeutic approaches. </div> <a href="javascript:ShowArticleAbstract(25);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%227-O-Methyl+aromadendrin%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">7-O-Methyl aromadendrin</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anti-inflammatory%2fantioxidant%2fantiapoptotic+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anti-inflammatory/antioxidant/antiapoptotic effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gastroprotective+effect%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gastroprotective effect</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sakuranetin%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sakuranetin</a></li></ul> <a href="javascript:ShowArticleKeywords(25);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> 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id="RootHolder_articleCitationPopup_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_articleCitationPopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleCitationPopup_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleCitationPopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1115091042" type="text/javascript">  </script> <div id="RootHolder_chartPopupControl_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:1000px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_chartPopupControl_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam"></span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content" style="overflow-x:hidden;overflow-y:scroll;">    </div> </div> </div> </div><div id="RootHolder_chartPopupControl_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_chartPopupControl_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_chartPopupControl_TL">Loading…</span></td> </tr> </table><div id="RootHolder_chartPopupControl_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_420552910" type="text/javascript">  </script> <div id="RootHolder_pcImportArticlesControl_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:50px;width:50px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_pcImportArticlesControl_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Import Articles</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="RootHolder_pcImportArticlesControl_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_pcImportArticlesControl_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_pcImportArticlesControl_TL">Loading…</span></td> </tr> </table><div id="RootHolder_pcImportArticlesControl_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_365297802" type="text/javascript">  </script> <div id="RootHolder_pcEditArticleControl_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_pcEditArticleControl_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Edit My Journal Article</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content" style="overflow-x:hidden;overflow-y:scroll;">    </div> </div> </div> </div><div id="RootHolder_pcEditArticleControl_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_pcEditArticleControl_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_pcEditArticleControl_TL">Loading…</span></td> </tr> </table><div id="RootHolder_pcEditArticleControl_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_298765222" type="text/javascript">  </script> <div id="RootHolder_userIndexComputePopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:200px;width:400px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header dxpc-withBtn" style="font-size:20px;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Article Influence Index</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="ai-content-container"> <p> <b>Calculation for <span id="RootHolder_userIndexComputePopup_InfluenceIndexTitle2">Article Influence Index</span></b> </p> <p> Total Citations in Crossref ÷ Total Articles = <span id="RootHolder_userIndexComputePopup_InfluenceIndexTitle3">Article Influence Index</span><sup class="standard-yellow">TM</sup> </p> </div> </div> </div> </div> </div><table id="RootHolder_userIndexComputePopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_userIndexComputePopup_TL">Loading…</span></td> </tr> </table><div id="RootHolder_userIndexComputePopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1286575841" type="text/javascript">  </script> <div id="RootHolder_articleExportPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:280px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow" style="font-size:11pt;"> <div class="dxpc-header drag dxpc-withBtn" style="font-size:20px;user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_articleExportPopup_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Export Articles to File</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="dxtcLite_MetropolisBlue dxtcSys dxtc-init dxtc-top dxtc-pc" id="RootHolder_articleExportPopup_ExportFilePageControl" style="width:100%;"> <ul class="dxtc-strip dxtc-row dxtc-stripContainer"> <li class="dxtc-leftIndent"> </li><li class="dxtc-tab dxtc-lead" style="display:none;"><a class="dxtc-link"><span class="dx-vam">Export Article Detail</span></a></li><li class="dxtc-activeTab dxtc-lead"><a class="dxtc-link"><span class="dx-vam">Export Article Detail</span></a></li><li class="dxtc-spacer"> </li><li class="dxtc-tab dxtc-last"><a class="dxtc-link"><span class="dx-vam">Export Citation Analysis</span></a></li><li class="dxtc-activeTab dxtc-last" style="display:none;"><a class="dxtc-link"><span class="dx-vam">Export Citation Analysis</span></a></li><li class="dxtc-rightIndent"> </li> </ul><div class="dxtc-content"> <div> <div> <div class="dxflFormLayout_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout" style="font-size:11pt;width:100%;"> <table class="dxflGroup_MetropolisBlue dxflGroupSys dxflAGSys" style="border-collapse:separate;"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_0" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_0_Cap" class="dxDefaultCursor dxflCaption_MetropolisBlue" style="font-weight:bold;">Searched Name:</span></td><td class="dxflNestedControlCell_MetropolisBlue"> <span class="dxeBase_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_SearchTermText1">Inflammation/metabolism (22902 results from Reference Citation Analysis)</span> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_1" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="padding-bottom:5px;"> <table> <tr> <td> <span style="font-weight: bold">Article Number From</span> </td> <td>   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ExportDetailStartIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" value="1" type="text" /></td> </tr> </table><script id="dxss_1662381219" type="text/javascript">  </script> </td> <td>  to   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ExportDetailEndIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" value="600" type="text" /></td> </tr> </table><script id="dxss_616434442" type="text/javascript">  </script> </td> <td>  </td> <td>(No more than 600 records at a time.) </td> </tr> </table> </div></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_2" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_I" style="font-weight:bold;">Indexing:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$selectDetailSource" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-100" class="dxeButton dxeButtonEditButton_MetropolisBlue dxeButtonEditClearButton_MetropolisBlue" onmousedown="ASPx.BEClear('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="display:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-100Img" class="dxEditors_edtClear_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="x" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$selectDetailSource$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr> <td></td> </tr> </table> </div></td> </tr> </table><script id="dxss_1167331127" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_54524200" type="text/javascript">  </script><script id="dxss_1678130197" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_4" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_I" style="font-weight:bold;">JCR Year:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_VI" type="hidden" value="2023" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$JCRYear" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" value="2023" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$JCRYear$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2023</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2022</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2021</td> </tr> </table> </div></td> </tr> </table><script id="dxss_830317689" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_167955898" type="text/javascript">  </script><script id="dxss_2013408041" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_5" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_I" style="font-weight:bold;">Format:</label><em class="dxflRequired_MetropolisBlue">*</em></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_ET" class="dxeValidDynEditorTable dxeRoot_MetropolisBlue"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_CC"><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat" style="width:200px;border-collapse:separate;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$DetailFileFormat" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$DetailFileFormat$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Excel</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Plain Text</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">PDF</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">WORD</td> </tr> </table> </div></td> </tr> </table><script id="dxss_1062639383" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_104403608" type="text/javascript">  </script></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_EC" class="dxeErrorCell_MetropolisBlue dxeErrorFrame_MetropolisBlue dxeErrorFrameSys dxeErrorCellSys dxeNoBorderLeft" style="vertical-align:middle;display:none;white-space:nowrap;">Invalid value</td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1973673553" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_6" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLTSys dxflItemSys dxflCheckBoxWithTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields_S" style="font-weight:bold;">Record Content:</label></td> </tr><tr> <td class="dxflNestedControlCell_MetropolisBlue"> <table> <tr> <td style="vertical-align: middle; padding: 5px;"> <table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields" style="color:#BD4100;"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields_S" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$cbSelectAllFields" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label>Select All Fields</label></td> </tr> </table><script id="dxss_1176833720" type="text/javascript">  </script> </td> </tr> <tr> <td style="padding: 5px;"> <table class="dxeCheckBoxList_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields" style="width:100%;border-collapse:separate;"> <tr> <td class="dxe"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields" /><table style="width:100%;"> <tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB0"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB0_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB0" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Author(s)</label></td> </tr> </table><script id="dxss_771536870" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB1"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB1_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB1" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Article Title</label></td> </tr> </table><script id="dxss_1086331335" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB2"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB2_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB2" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Keywords</label></td> </tr> </table><script id="dxss_1308541020" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB3"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB3_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB3" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">MESH Headings</label></td> </tr> </table><script id="dxss_896786043" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB4"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB4_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB4" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Journal Title</label></td> </tr> </table><script id="dxss_450242410" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB5"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB5_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB5" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Year</label></td> </tr> </table><script id="dxss_765036875" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB6"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB6_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB6" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Article Type</label></td> </tr> </table><script id="dxss_1629835480" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB7"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB7_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB7" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Language</label></td> </tr> </table><script id="dxss_1218080503" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB8"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB8_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB8" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Published Date</label></td> </tr> </table><script id="dxss_1428514578" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB9"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB9_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB9" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">First Author</label></td> </tr> </table><script id="dxss_1113720113" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB10"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB10_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB10" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">First Author’s Affiliations</label></td> </tr> </table><script id="dxss_310841941" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB11"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB11_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB11" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Corresponding Author</label></td> </tr> </table><script id="dxss_1301541094" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB12"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB12_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB12" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Corresponding Author’s Affiliations</label></td> </tr> </table><script id="dxss_675718561" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB13"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB13_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB13" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Email</label></td> </tr> </table><script id="dxss_2006865700" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB14"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB14_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB14" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">All Authors's Affiliations</label></td> </tr> </table><script id="dxss_1204905793" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB15"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB15_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB15" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Grant</label></td> </tr> </table><script id="dxss_407477242" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB16"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB16_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB16" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">ISSN</label></td> </tr> </table><script id="dxss_218345291" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB17"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB17_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB17" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Publisher</label></td> </tr> </table><script id="dxss_1394037744" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB18"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB18_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB18" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Indexing / Abstracting</label></td> </tr> </table><script id="dxss_319681069" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB19"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB19_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB19" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Impact Factor</label></td> </tr> </table><script id="dxss_1292701966" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB20"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB20_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB20" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">JCR Quartile</label></td> </tr> </table><script id="dxss_1844280938" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB21"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB21_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB21" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Impact Index Per Article</label></td> </tr> </table><script id="dxss_838303323" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB22"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB22_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB22" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Category</label></td> </tr> </table><script id="dxss_1464125856" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB23"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB23_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB23" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Times Cited in RCA</label></td> </tr> </table><script id="dxss_148257179" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB24"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB24_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB24" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Peer-Reviewed Journal</label></td> </tr> </table><script id="dxss_950217086" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB25"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB25_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB25" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Open Access</label></td> </tr> </table><script id="dxss_1732367175" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB26"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB26_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB26" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">DOI</label></td> </tr> </table><script id="dxss_1936777588" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB27"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB27_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB27" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">PMID</label></td> </tr> </table><script id="dxss_745806673" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB28"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB28_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB28" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Citation</label></td> </tr> </table><script id="dxss_1835441810" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB29"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB29_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB29" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Indexed in RCA</label></td> </tr> </table><script id="dxss_847142451" type="text/javascript">  </script></td><td></td><td></td> </tr> </table></td> </tr> </table><script id="dxss_1169734383" type="text/javascript">  </script> </td> </tr> </table> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_7" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue"> <a class="dxeHyperlink_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportedDetailFileLink" target="_blank" rel="noopener noreferrer">Click to Download the Exported File</a><script id="dxss_1198171345" type="text/javascript">  </script> </div></td> </tr> </table> </div><script id="dxss_1960175520" type="text/javascript">  </script> </div> </div><div style="display:none;"> <div> <div class="dxflFormLayout_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout" style="font-size:11pt;width:100%;"> <table class="dxflGroup_MetropolisBlue dxflGroupSys dxflAGSys" style="border-collapse:separate;"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_0" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_0_Cap" class="dxDefaultCursor dxflCaption_MetropolisBlue" style="font-weight:bold;">Searched Name:</span></td><td class="dxflNestedControlCell_MetropolisBlue"> <span class="dxeBase_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_SearchTermText2">Inflammation/metabolism (22902 results from Reference Citation Analysis)</span> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_1" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="padding-bottom:10px;"> <table> <tr> <td> <span style="font-weight: bold">Article Number From</span> </td> <td>   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$ExportStartIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" value="1" type="text" /></td> </tr> </table><script id="dxss_814491935" type="text/javascript">  </script> </td> <td>  to   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$ExportEndSIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" value="600" type="text" /></td> </tr> </table><script id="dxss_1331245653" type="text/javascript">  </script> </td> <td>  </td> <td>(No more than 600 records at a time.) </td> </tr> </table> </div></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_2" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:10px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_I" style="font-weight:bold;">Indexing:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$selectSource" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-100" class="dxeButton dxeButtonEditButton_MetropolisBlue dxeButtonEditClearButton_MetropolisBlue" onmousedown="ASPx.BEClear('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="display:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-100Img" class="dxEditors_edtClear_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="x" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$selectSource$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr> <td></td> </tr> </table> </div></td> </tr> </table><script id="dxss_2046065225" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_1926633208" type="text/javascript">  </script><script id="dxss_228619664" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_4" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:20px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_I" style="font-weight:bold;">Format:</label><em class="dxflRequired_MetropolisBlue">*</em></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_ET" class="dxeValidDynEditorTable dxeRoot_MetropolisBlue"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_CC"><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat" style="width:200px;border-collapse:separate;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_VI" type="hidden" value="1" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$FileFormat" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" value="Excel" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$FileFormat$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Excel</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Plain Text</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">PDF</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">WORD</td> </tr> </table> </div></td> </tr> </table><script id="dxss_1509722775" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_960798088" type="text/javascript">  </script></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_EC" class="dxeErrorCell_MetropolisBlue dxeErrorFrame_MetropolisBlue dxeErrorFrameSys dxeErrorCellSys dxeNoBorderLeft" style="vertical-align:middle;display:none;white-space:nowrap;">Invalid value</td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_835950349" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_5" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue"> <a class="dxeHyperlink_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportedFileLink" target="_blank" rel="noopener noreferrer">Click to Download the Exported File</a><script id="dxss_308093146" type="text/javascript">  </script> </div></td> </tr> </table> </div><script id="dxss_424125632" type="text/javascript">  </script> </div> </div> </div> </div><b class="dx-clear"></b><table id="RootHolder_articleExportPopup_ExportFilePageControl_LP" class="dxtcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_TL">Loading…</span></td> </tr> </table><script id="dxss_2124675053" type="text/javascript">  </script> </div> </div><div class="dxpc-footer"> <div class="popup-footer-button-container"> <div class="dxbButton_MetropolisBlue DefaultButton dxbButtonSys dxbTSys" id="RootHolder_articleExportPopup_TPCFm1_btnExportArticles" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxb"> <input id="RootHolder_articleExportPopup_TPCFm1_btnExportArticles_I" class="dxb-hb" value="Export" type="submit" name="ctl00$RootHolder$articleExportPopup$TPCFm1$TC$btnExportArticles" /><span class="dx-vam">Export</span> </div> </div><script id="dxss_77486387" type="text/javascript">  </script>    <div class="dxbButton_MetropolisBlue DefaultButton dxbButtonSys dxbTSys" id="RootHolder_articleExportPopup_TPCFm1_btnCancel" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxb"> <input id="RootHolder_articleExportPopup_TPCFm1_btnCancel_I" class="dxb-hb" value="Cancel" type="submit" name="ctl00$RootHolder$articleExportPopup$TPCFm1$TC$btnCancel" /><span class="dx-vam">Cancel</span> </div> </div><script id="dxss_2118985763" type="text/javascript">  </script> </div> </div> </div> </div><div id="RootHolder_articleExportPopup_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_articleExportPopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="font-size:11pt;left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="font-size:11pt;padding-left:0px;"><span id="RootHolder_articleExportPopup_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_578446409" type="text/javascript">  </script> </div> <div class="bottom-part cl"> © 2004-2024 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA </div> <div class="scroll"> <a href="#top" target="_self"> <img src="/Contents/Images/backtop3.png" /> </a> </div> <div id="categorySelectorPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="font-size:20px;user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Select the Category</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="categorySelectorPopup_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="categorySelectorPopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="categorySelectorPopup_TL">Loading…</span></td> </tr> </table><div id="categorySelectorPopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_166253781" type="text/javascript">  </script> <div id="pcLoginPopUp_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:700px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="pcLoginPopUp_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="pcLoginPopUp_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="pcLoginPopUp_TL">Loading…</span></td> </tr> </table><div id="pcLoginPopUp_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_430910140" type="text/javascript">  </script> <div id="aiComputePopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:200px;width:300px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header dxpc-withBtn" style="font-size:20px;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Impact Index Per Article</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="ai-content-container"> <p> <b>Calculation for Impact Index Per Article</b> </p> <p> Times Cited ÷ Number of Years = Impact Index Per Article<sup class="standard-yellow">TM</sup> </p> </div> </div> </div> </div> </div><table id="aiComputePopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="aiComputePopup_TL">Loading…</span></td> </tr> </table><div id="aiComputePopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_698179129" type="text/javascript">  </script> <script type="text/javascript"> //<![CDATA[ var callBackFrameUrl='/WebResource.axd?d=beToSAE3vdsL1QUQUxjWdX-3aFLejnBliGvqSCZYULGFdxZmRlcJcqs71AKVNTQEXljNmd0slFkUZ_AFaCke4Q2&t=638628207619783110'; WebForm_InitCallback();//]]> </script> </form> </body> </html>