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variant="hero--variant-a"><h1 class="hero__headline" slot="headline">Innovation</h1><div class="hero__text" slot="text">Driven by our passion for what we do, our autonomy in how we find solutions, and the strength of our R&amp;D structure we can take on the most complex challenges in healthcare.</div></roche-staging-hero></roche-grid><roche-grid layout="8-4" full-width="false" disable-rtl="true" color=""><roche-headline slot="left" level="2"><h2 class="headline headline--2">Innovation across the Roche Group</h2></roche-headline><div slot="left" dir="ltr" class="rich-text"><p>Our close strategic partnerships across the Group, and our diverse mix of autonomous innovation engines gives us a rich diversity of expertise and scientific thinking, as we seek to discover and develop solutions to the biggest questions in healthcare today.</p></div></roche-grid><roche-grid layout="4-4-4" full-width="false" disable-rtl="true" color=""><roche-headline slot="left" level="1"><h1 class="headline headline--1">13 billion</h1></roche-headline><div slot="left" dir="ltr" class="rich-text"><p>CHF invested in R&amp;D in 2024</p></div><roche-headline slot="center" level="1"><h1 class="headline headline--1">17</h1></roche-headline><div slot="center" dir="ltr" class="rich-text"><p>countries with Roche innovation centers</p></div><roche-headline slot="right" level="1"><h1 class="headline headline--1">&gt;100,000</h1></roche-headline><div slot="right" dir="ltr" class="rich-text"><p>dedicated employees</p></div></roche-grid><roche-grid layout="12" full-width="false" disable-rtl="true" color=""><div slot=""><section class="hero-teaser"><div class="hero-teaser__info-container"><div class="hero-teaser__text-container"><div class="hero-teaser__title-container"><h2 class="hero-teaser__title">Roche Group Innovation Engines</h2></div><p>To discover and develop the next breakthroughs, we have built a network of independent innovation engines around the world.</p></div><div class="hero-teaser__button-container"><roche-button style="margin:0" href="/innovation/structure/" appearance="secondary" text="Explore our structure"></roche-button></div></div><div class="hero-teaser__image-container"><roche-image style="margin:0" class="teaser-image" src="https://assets.roche.com/f/176343/1440x900/99e2b2e0ff/teams-and-structure-teaser.jpg/m/$0x$1/filters:format(webp):quality(90)/" ratio="1:1" alt=""></roche-image></div></section></div><div slot=""><section class="hero-teaser"><div class="hero-teaser__image-container"><roche-image style="margin:0" class="teaser-image" src="https://assets.roche.com/f/176343/1440x900/87eb5ee6c9/innovation-process-teaser.jpg/m/$0x$1/filters:format(webp):quality(90)/" ratio="1:1" alt=""></roche-image></div><div class="hero-teaser__info-container"><div class="hero-teaser__text-container"><div class="hero-teaser__title-container"><h2 class="hero-teaser__title">Innovation process</h2></div><p>It&#x27;s a long way from an idea to medical innovation. Here&#x27;s how we get there.</p></div><div class="hero-teaser__button-container"><roche-button style="margin:0" href="/innovation/process/" appearance="secondary" text="Discover our processes"></roche-button></div></div></section></div></roche-grid><roche-grid layout="8" full-width="false" disable-rtl="true" color="grey-100"><roche-slider animation="" slides-per-page="1" uid="a0f3a712-e055-475e-9033-c34bae64804d" id="a0f3a712-e055-475e-9033-c34bae64804d" storyid="318948383"><roche-slider-item uid="454796cd-d870-48da-8020-54edc57d7728" id="454796cd-d870-48da-8020-54edc57d7728" storyid="318948383"><div><figure class="roche-quote"><div class="roche-quote__content"><blockquote><p class="roche-quote__text">With patient and societal health needs in mind, we leverage our passion and curiosity for science to create revolutionary medicines that can change patients&#x27; lives.</p></blockquote><figcaption><div class="roche-quote__subline"><div><div class="subline"><div class="subline__author-container"><div class="subline__author-description-container"><p class="subline__author">Hans Clevers</p><p class="subline__author-description">Head of Roche Pharma Research and Early Development (pRED)</p></div></div></div></div></div></figcaption></div></figure></div></roche-slider-item><roche-slider-item uid="a3a8147c-2a58-401e-a17a-f4d7a0a37867" id="a3a8147c-2a58-401e-a17a-f4d7a0a37867" storyid="318948383"><div><figure class="roche-quote"><div class="roche-quote__content"><blockquote><p class="roche-quote__text">Great people join us because they want to work on the hardest problems in science.</p></blockquote><figcaption><div class="roche-quote__subline"><div><div class="subline"><div class="subline__author-container"><div class="subline__author-description-container"><p class="subline__author">Aviv Regev</p><p class="subline__author-description">Head of Genentech Research and Early Development (gRED)</p></div></div></div></div></div></figcaption></div></figure></div></roche-slider-item><roche-slider-item uid="73dc50a6-fd5b-4b59-9f93-833d5451730c" id="73dc50a6-fd5b-4b59-9f93-833d5451730c" storyid="318948383"><div><figure class="roche-quote"><div class="roche-quote__content"><blockquote><p class="roche-quote__text">The development of transformative therapeutics and diagnostics is a tough business... This is something that the unique structure of the Roche Group really provides.</p></blockquote><figcaption><div class="roche-quote__subline"><div><div class="subline"><div class="subline__author-container"><div class="subline__author-description-container"><p class="subline__author">Palani Kumaresan</p><p class="subline__author-description">Head of Roche Diagnostics Solutions</p></div></div></div></div></div></figcaption></div></figure></div></roche-slider-item><roche-slider-item uid="dbbd5f0f-a5e0-4334-885a-85c57a2aa4e7" id="dbbd5f0f-a5e0-4334-885a-85c57a2aa4e7" storyid="318948383"><div><figure class="roche-quote"><div class="roche-quote__content"><blockquote><p class="roche-quote__text">The benefit of being part of the Roche Group is the huge amount of expertise, experience and resources that we have across the company.</p></blockquote><figcaption><div class="roche-quote__subline"><div><div class="subline"><div class="subline__author-container"><div class="subline__author-description-container"><p class="subline__author">Tom Albert</p><p class="subline__author-description">Global Head of Research and Early Development, Roche Diagnostics Solutions</p></div></div></div></div></div></figcaption></div></figure></div></roche-slider-item><roche-slider-item uid="e1dc479a-c200-47d3-a7c8-4ff33ec20894" id="e1dc479a-c200-47d3-a7c8-4ff33ec20894" storyid="318948383"><div><figure class="roche-quote"><div class="roche-quote__content"><blockquote><p class="roche-quote__text">It is the tremendous diversity of thought and the diversity of decision making within the Roche Group, and across our partnerships, that leads to the development of groundbreaking therapies and diagnostics for patients.</p></blockquote><figcaption><div class="roche-quote__subline"><div><div class="subline"><div class="subline__author-container"><div class="subline__author-description-container"><p class="subline__author">James Sabry</p><p class="subline__author-description">Global Head of Roche Pharma Partnering</p></div></div></div></div></div></figcaption></div></figure></div></roche-slider-item></roche-slider></roche-grid><roche-grid layout="6-1-5" full-width="false" disable-rtl="true" color=""><roche-image src="{&quot;src&quot;:&quot;https://assets.roche.com/f/176343/608x355/d24456b965/rectangle-645-3.jpg/m/$0x$1/filters:format(webp):quality(90)/&quot;,&quot;caption&quot;:&quot;&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;alt&quot;:&quot;&quot;}" ratio="16:9" position="center" brightcove-id="" slot="left" uid="db27a108-d987-4781-98ef-190418f04360" id="db27a108-d987-4781-98ef-190418f04360" storyid="318948383"></roche-image><roche-headline slot="right" level="2"><h2 class="headline headline--2">Ethical standards</h2></roche-headline><div slot="right" dir="ltr" class="rich-text"><p>Questions inevitably arise as we explore the potential of cutting-edge technologies. We are committed to <span>adhering</span> to the highest ethical standards in research and development.</p></div><roche-button appearance="secondary" left-icon="" right-icon="" target="" href="/innovation/ethical-standards/" text="How do we meet them" slot="right"><a href="/innovation/ethical-standards/">How do we meet them</a></roche-button></roche-grid><roche-grid layout="5-1-6" full-width="false" disable-rtl="true" color=""><roche-headline slot="left" level="2"><h2 class="headline headline--2">Partnering</h2></roche-headline><div slot="left" dir="ltr" class="rich-text"><p>Alongside our unique Group structure, our strong network of external partners, drives the creativity and innovation needed for breakthrough research and development</p></div><roche-button appearance="secondary" left-icon="" right-icon="" target="" href="/innovation/partnering/" text="Get to know partnering" slot="left"><a href="/innovation/partnering/">Get to know partnering</a></roche-button><roche-image src="{&quot;src&quot;:&quot;https://assets.roche.com/f/176343/608x342/ad437a7870/rectangle-645-4.jpg/m/$0x$1/filters:format(webp):quality(90)/&quot;,&quot;caption&quot;:&quot;&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;alt&quot;:&quot;&quot;}" ratio="16:9" position="center" brightcove-id="" slot="right" uid="2d225dde-a36d-48a9-b2b9-119397ecc899" id="2d225dde-a36d-48a9-b2b9-119397ecc899" storyid="318948383"></roche-image></roche-grid><roche-grid layout="12" full-width="false" disable-rtl="true" color="neutral-gradient-bottom-right"><roche-side-by-side vertical-alignment="middle" horizontal-alignment="space-between" uid="1f081de6-5006-4455-9974-96e91a396be3" id="1f081de6-5006-4455-9974-96e91a396be3" storyid="318948383"><div dir="ltr" class="rich-text"><roche-headline level="6" headline="Stories of "></roche-headline><roche-headline level="3" headline="Innovation across the Roche Group"></roche-headline></div><roche-text-link href="/stories/" target="_self" right-icon="arrow-right" text="See all stories"><a href="/stories/">See all stories</a></roche-text-link></roche-side-by-side><roche-slider disable-auto-init="true" in-app-with-virtualised-dom="true" loop slides-per-page="3" transition="by-page"><div><roche-slider-item><a class="story-teaser story-teaser--variant-a" aria-label="Future cures are in our genes" href="/stories/future-of-gene-therapy-in-partnering" style="--teaser-hover-offset:0px"><article><div class="story-teaser__image-container"><roche-image alt="" style="margin:0" src="https://assets.roche.com/f/176343/740x416/fb2c387058/future-of-gene-therapy-in-partnering-teaser.png/m/$0x$1/filters:format(webp):quality(90)/" ratio="4:3"></roche-image></div><div class="story-teaser__details"><div class="story-teaser__description-container"><h3 class="story-teaser__title">Future cures are in our genes</h3><p class="story-teaser__description">The next generation of pioneering medicines, led by gene therapy, is blazing a path towards truly personalised global healthcare, strengthened by partnering.</p></div><roche-date date="2021-11-03T11:33:16.000Z" format="dateFull" class="story-teaser__date"></roche-date></div></article></a></roche-slider-item><roche-slider-item><a class="story-teaser story-teaser--variant-a" aria-label="External innovation opens new doors for advancing science" href="/stories/james-sabry-external-innovation-in-partnering" style="--teaser-hover-offset:0px"><article><div class="story-teaser__image-container"><roche-image alt="" style="margin:0" src="https://assets.roche.com/f/176343/740x416/e2dcdb6117/james-sabry-external-innovation-in-partnering-teaser.jpg/m/$0x$1/filters:format(webp):quality(90)/" ratio="4:3"></roche-image></div><div class="story-teaser__details"><div class="story-teaser__description-container"><h3 class="story-teaser__title">External innovation opens new doors for advancing science</h3><p class="story-teaser__description">Global Head of Pharma Partnering James Sabry is excited to embrace the potential of external innovation and innovative partners.</p></div><roche-date date="2020-01-06T22:59:00.000Z" format="dateFull" class="story-teaser__date"></roche-date></div></article></a></roche-slider-item><roche-slider-item><a class="story-teaser story-teaser--variant-a" aria-label="Joining forces in neuroscience" href="/stories/joining-forces-in-neuroscience" style="--teaser-hover-offset:0px"><article><div class="story-teaser__image-container"><roche-image alt="" style="margin:0" src="https://assets.roche.com/f/176343/740x416/cdc3878d2e/joining-forces-in-neuroscience-teaser.jpg/m/$0x$1/filters:format(webp):quality(90)/" ratio="4:3"></roche-image></div><div class="story-teaser__details"><div class="story-teaser__description-container"><h3 class="story-teaser__title">Joining forces in neuroscience</h3><p class="story-teaser__description">Neurological disorders pose some of the greatest challenges and areas of unmet medical need. We are joining forces with others who are studying these challenges.</p></div><roche-date date="2021-06-01T01:00:00.000Z" format="dateFull" class="story-teaser__date"></roche-date></div></article></a></roche-slider-item><roche-slider-item><a class="story-teaser story-teaser--variant-a" aria-label="Making the Unknown Known" href="/stories/personalised-healthcare-in-cup" style="--teaser-hover-offset:0px"><article><div class="story-teaser__image-container"><roche-image alt="" style="margin:0" src="https://assets.roche.com/f/176343/740x416/7ddc9f33f2/personalised-healthcare-in-cup-teaser.png/m/$0x$1/filters:format(webp):quality(90)/" ratio="4:3"></roche-image></div><div class="story-teaser__details"><div class="story-teaser__description-container"><h3 class="story-teaser__title">Making the Unknown Known</h3><p class="story-teaser__description">Could comprehensive genomic profiling improve outcomes for patients with one of the most deadly and poorly understood cancers鈥擟ancer of Unknown Primary Origin? A new trial seeks to find out.</p></div><roche-date date="2023-11-16T00:00:00.000Z" format="dateFull" class="story-teaser__date"></roche-date></div></article></a></roche-slider-item><roche-slider-item><a class="story-teaser story-teaser--variant-a" aria-label="Advances in the cancer-immunity cycle" href="/stories/partnering-to-drive-innovation-in-cancer-immunotherapy" style="--teaser-hover-offset:0px"><article><div class="story-teaser__image-container"><roche-image alt="" style="margin:0" src="https://assets.roche.com/f/176343/740x416/27cf778d1e/partnering-to-drive-innovation-in-cancer-immunotherapy-teaser.png/m/$0x$1/filters:format(webp):quality(90)/" ratio="4:3"></roche-image></div><div class="story-teaser__details"><div class="story-teaser__description-container"><h3 class="story-teaser__title">Advances in the cancer-immunity cycle</h3><p class="story-teaser__description">We鈥檙e partnering with many different stakeholders to find the most effective way for the immune system to identify and kill cancer cells.</p></div><roche-date date="2019-05-29T00:00:00.000Z" format="dateFull" class="story-teaser__date"></roche-date></div></article></a></roche-slider-item><roche-slider-item><a class="story-teaser story-teaser--variant-a" aria-label="Data can change your life; it probably already has" href="/stories/data-can-change-your-life" style="--teaser-hover-offset:0px"><article><div class="story-teaser__image-container"><roche-image alt="" style="margin:0" src="https://assets.roche.com/f/176343/740x416/71237a201e/data-can-change-your-life-teaser.jpg/m/$0x$1/filters:format(webp):quality(90)/" ratio="4:3"></roche-image></div><div class="story-teaser__details"><div class="story-teaser__description-container"><h3 class="story-teaser__title">Data can change your life; it probably already has</h3><p class="story-teaser__description">How data can improve and save lives, and why it matters during the COVID-19 crisis and beyond.</p></div><roche-date date="2021-12-16T13:55:20.000Z" format="dateFull" class="story-teaser__date"></roche-date></div></article></a></roche-slider-item></div></roche-slider></roche-grid><roche-grid layout="6-6" full-width="false" disable-rtl="true" color="split-gradient-radial"><roche-headline slot="left" level="2"><h2 class="headline headline--2">Discover more</h2></roche-headline><roche-teaser layout="teaser-variant-b-without-image" teaser-title="Careers" teaser-overline="tbd" teaser-description="Find jobs and learn more about exciting career opportunities at Roche, one of the world&#x27;s leading research-based healthcare companies. " teaser-image="https://assets.roche.com/f/176343/370x208/80cf265b71/teaser-placeholder.jpg/m/$0x$1/filters:format(webp):quality(90)/" teaser-url="https://careers.roche.com/" loaded="false" is-external-link="false" slot="right"><a href="https://careers.roche.com/">Careers</a></roche-teaser><roche-teaser layout="teaser-variant-a-without-image" teaser-image="https://assets.roche.com/f/176343/640x427/68ced0b0ac/focus-areas-teaser.png/m/$0x$1/filters:format(webp):quality(90)/" teaser-title="Focus areas" teaser-overline="Solutions" teaser-description="Finding innovative solutions for unmet medical needs is at the heart of what we do. Our ideas and research help save lives." teaser-date="2021-10-20T12:48:56.540Z" teaser-url="/solutions/focus-areas/" loaded="true" slot="right" is-teaser-in-draft="false"></roche-teaser><roche-teaser layout="teaser-variant-b-without-image" teaser-title="How can immuno-oncology change the care for cancer patients? 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