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Previous studies have examined the association between specific mental disorders, particularly mood and anxiety disorders, and substance-related disorders; but the temporal link between them remains unclear. This study aimed to examine" /> <meta name="twitter:image" content="https://0.academia-photos.com/46522618/12303232/13698109/s200_chiu-ying.chen.jpg" /> <meta property="fb:app_id" content="2369844204" /> <meta property="og:type" content="article" /> <meta property="og:url" content="https://www.academia.edu/80718943/The_Temporal_Relationship_between_Selected_Mental_Disorders_and_Substance_Related_Disorders_A_Nationwide_Population_Based_Cohort_Study" /> <meta property="og:title" content="The Temporal Relationship between Selected Mental Disorders and Substance-Related Disorders: A Nationwide Population-Based Cohort Study" /> <meta property="og:image" content="http://a.academia-assets.com/images/open-graph-icons/fb-paper.gif" /> <meta property="og:description" content="Introduction. Previous studies have examined the association between specific mental disorders, particularly mood and anxiety disorders, and substance-related disorders; but the temporal link between them remains unclear. This study aimed to examine" /> <meta property="article:author" content="https://independent.academia.edu/ChenChiuying" /> <meta name="description" content="Introduction. Previous studies have examined the association between specific mental disorders, particularly mood and anxiety disorders, and substance-related disorders; but the temporal link between them remains unclear. This study aimed to examine" /> <title>(PDF) The Temporal Relationship between Selected Mental Disorders and Substance-Related Disorders: A Nationwide Population-Based Cohort Study | Chiu-ying Chen - Academia.edu</title> <link rel="canonical" href="https://www.academia.edu/80718943/The_Temporal_Relationship_between_Selected_Mental_Disorders_and_Substance_Related_Disorders_A_Nationwide_Population_Based_Cohort_Study" /> <script async src="https://www.googletagmanager.com/gtag/js?id=G-5VKX33P2DS"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-5VKX33P2DS', { cookie_domain: 'academia.edu', send_page_view: false, }); gtag('event', 'page_view', { 'controller': "single_work", 'action': "show", 'controller_action': 'single_work#show', 'logged_in': 'false', 'edge': 'unknown', // Send nil if there is no A/B test bucket, in case some records get logged // with missing data - that way we can distinguish between the two cases. // ab_test_bucket should be of the form <ab_test_name>:<bucket> 'ab_test_bucket': null, }) </script> <script> var $controller_name = 'single_work'; var $action_name = "show"; var $rails_env = 'production'; var $app_rev = '49879c2402910372f4abc62630a427bbe033d190'; var $domain = 'academia.edu'; var $app_host = "academia.edu"; var $asset_host = "academia-assets.com"; var $start_time = new Date().getTime(); var $recaptcha_key = "6LdxlRMTAAAAADnu_zyLhLg0YF9uACwz78shpjJB"; var $recaptcha_invisible_key = "6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj"; var $disableClientRecordHit = false; </script> <script> window.require = { config: function() { return function() {} } } </script> <script> window.Aedu = window.Aedu || {}; window.Aedu.hit_data = null; window.Aedu.serverRenderTime = new Date(1732523383000); window.Aedu.timeDifference = new Date().getTime() - 1732523383000; </script> <script type="application/ld+json">{"@context":"https://schema.org","@type":"ScholarlyArticle","abstract":"Introduction. Previous studies have examined the association between specific mental disorders, particularly mood and anxiety disorders, and substance-related disorders; but the temporal link between them remains unclear. This study aimed to examine whether individuals with specific mental disorders, including affective psychoses, neurotic disorders, schizophrenia, personality disorders, and adjustment reaction, have higher risks for subsequently developing substance-related disorders compared to those without. Methods. A large-scale study with longitudinal data was conducted using the Taiwan National Health Insurance Research Database (NHIRD) consisting of 2,000,118 patients’ medical records from 2000 to 2009. A total of 124,423 people diagnosed with selected mental disorders and the same number of people without the diagnoses of the selected disorders were identified between January 1, 2001, and December 31, 2006, and followed up for the diagnoses of substance-related disorders ti...","author":[{"@context":"https://schema.org","@type":"Person","name":"Chiu-ying Chen"}],"contributor":[],"dateCreated":"2022-06-04","dateModified":null,"datePublished":"2018-01-01","headline":"The Temporal Relationship between Selected Mental Disorders and Substance-Related Disorders: A Nationwide Population-Based Cohort Study","inLanguage":"en","keywords":["Psychiatry","Medicine"],"locationCreated":null,"publication":"Psychiatry Journal","publisher":{"@context":"https://schema.org","@type":"Organization","name":"Hindawi Limited"},"image":null,"thumbnailUrl":null,"url":"https://www.academia.edu/80718943/The_Temporal_Relationship_between_Selected_Mental_Disorders_and_Substance_Related_Disorders_A_Nationwide_Population_Based_Cohort_Study","sourceOrganization":[{"@context":"https://schema.org","@type":"EducationalOrganization","name":null}]}</script><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/single_work_page/loswp-352e32ba4e89304dc0b4fa5b3952eef2198174c54cdb79066bc62e91c68a1a91.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/body-8d679e925718b5e8e4b18e9a4fab37f7eaa99e43386459376559080ac8f2856a.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/button-3cea6e0ad4715ed965c49bfb15dedfc632787b32ff6d8c3a474182b231146ab7.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/text_button-73590134e40cdb49f9abdc8e796cc00dc362693f3f0f6137d6cf9bb78c318ce7.css" 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Previous studies have examined the association between specific mental disorders, particularly mood and anxiety disorders, and substance-related disorders; but the temporal link between them remains unclear. This study aimed to examine whether individuals with specific mental disorders, including affective psychoses, neurotic disorders, schizophrenia, personality disorders, and adjustment reaction, have higher risks for subsequently developing substance-related disorders compared to those without. Methods. A large-scale study with longitudinal data was conducted using the Taiwan National Health Insurance Research Database (NHIRD) consisting of 2,000,118 patients’ medical records from 2000 to 2009. A total of 124,423 people diagnosed with selected mental disorders and the same number of people without the diagnoses of the selected disorders were identified between January 1, 2001, and December 31, 2006, and followed up for the diagnoses of substance-related disorders ti...","publisher":"Hindawi Limited","publication_date":"2018,,","publication_name":"Psychiatry Journal"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"The Temporal Relationship between Selected Mental Disorders and Substance-Related Disorders: A Nationwide Population-Based Cohort Study","broadcastable":false,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [46522618]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container js-loswp-work-card"><div class="ds-work-card--cover"><div class="ds-work-cover--wrapper"><div class="ds-work-cover--container"><button class="ds-work-cover--clickable js-swp-download-button" data-signup-modal="{"location":"swp-splash-paper-cover","attachmentId":87007985,"attachmentType":"pdf"}"><img alt="First page of “The Temporal Relationship between Selected Mental Disorders and Substance-Related Disorders: A Nationwide Population-Based Cohort Study”" class="ds-work-cover--cover-thumbnail" src="https://0.academia-photos.com/attachment_thumbnails/87007985/mini_magick20220604-20048-1is226x.png?1654410034" /><img alt="PDF Icon" class="ds-work-cover--file-icon" src="//a.academia-assets.com/assets/single_work_splash/adobe.icon-574afd46eb6b03a77a153a647fb47e30546f9215c0ee6a25df597a779717f9ef.svg" /><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">The Temporal Relationship between Selected Mental Disorders and Substance-Related Disorders: A Nationwide Population-Based Cohort Study</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="46522618" href="https://independent.academia.edu/ChenChiuying"><img alt="Profile image of Chiu-ying Chen" class="ds-work-card--author-avatar" src="https://0.academia-photos.com/46522618/12303232/13698109/s65_chiu-ying.chen.jpg" />Chiu-ying Chen</a></div><p class="ds-work-card--detail ds2-5-body-sm">2018, Psychiatry Journal</p><p class="ds-work-card--work-abstract ds-work-card--detail ds2-5-body-md">Introduction. Previous studies have examined the association between specific mental disorders, particularly mood and anxiety disorders, and substance-related disorders; but the temporal link between them remains unclear. This study aimed to examine whether individuals with specific mental disorders, including affective psychoses, neurotic disorders, schizophrenia, personality disorders, and adjustment reaction, have higher risks for subsequently developing substance-related disorders compared to those without. Methods. A large-scale study with longitudinal data was conducted using the Taiwan National Health Insurance Research Database (NHIRD) consisting of 2,000,118 patients’ medical records from 2000 to 2009. A total of 124,423 people diagnosed with selected mental disorders and the same number of people without the diagnoses of the selected disorders were identified between January 1, 2001, and December 31, 2006, and followed up for the diagnoses of substance-related disorders ti...</p><div class="ds-work-card--button-container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--work-card","attachmentId":87007985,"attachmentType":"pdf","workUrl":"https://www.academia.edu/80718943/The_Temporal_Relationship_between_Selected_Mental_Disorders_and_Substance_Related_Disorders_A_Nationwide_Population_Based_Cohort_Study"}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--work-card","attachmentId":87007985,"attachmentType":"pdf","workUrl":"https://www.academia.edu/80718943/The_Temporal_Relationship_between_Selected_Mental_Disorders_and_Substance_Related_Disorders_A_Nationwide_Population_Based_Cohort_Study"}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div></div><div data-auto_select="false" data-client_id="331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b" data-doc_id="87007985" data-landing_url="https://www.academia.edu/80718943/The_Temporal_Relationship_between_Selected_Mental_Disorders_and_Substance_Related_Disorders_A_Nationwide_Population_Based_Cohort_Study" data-login_uri="https://www.academia.edu/registrations/google_one_tap" data-moment_callback="onGoogleOneTapEvent" id="g_id_onload"></div><div class="ds-top-related-works--grid-container"><div class="ds-related-content--container ds-top-related-works--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="0" data-entity-id="25018642" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/25018642/Comorbidity_of_substance_use_disorders_with_mood_and_anxiety_disorders">Comorbidity of substance use disorders with mood and anxiety disorders</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="40668299" href="https://independent.academia.edu/RBijl">R. 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clinician","attachmentId":110405883,"attachmentType":"pdf","work_url":"https://www.academia.edu/113450266/Comorbidity_of_mental_disorders_and_substance_use_A_brief_guide_for_the_primary_care_clinician","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/113450266/Comorbidity_of_mental_disorders_and_substance_use_A_brief_guide_for_the_primary_care_clinician"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="64950255" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/64950255/Psychiatric_Comorbidity_of_Alcohol_Dependent_Patients_Admitting_in_Chiang_Mai_Drug_Dependence_Treatment_Center">Psychiatric Comorbidity of Alcohol Dependent Patients Admitting in Chiang Mai Drug Dependence Treatment Center</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="7436915" href="https://independent.academia.edu/AranyaPhajuy">Aranya Phajuy</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2013</p><p class="ds-related-work--abstract ds2-5-body-sm">Objective: To examine the prevalence of psychiatric comorbidity in alcohol dependent patients. Method: Of 120 alcohol dependent subjects who recovered at least 1 week from detoxification program admission at Chiang Mai Drug Dependence Treatment Center during May to July 2006 were recruited. The Mini international neuropsychiatric structure interview: M.I.N.I - Thai Version 5.0.0 was using for psychiatric diagnosis by trained interviewers. Data analysis used descriptive statistic e.g. mean, SD, percentage. Results: The prevalence of psychiatric comorbidity in alcohol dependent patients was 60%. The first 5 ranked of psychiatric comorbidity were lifetime psychotic disorder, lifetime suicidality, lifetime manic episode, current major depressive, current generalized anxiety disorder and lifetime antisocial personality disorder, 27.5%, 18.3%, 15.8%, 15.0%, 7.5% and 7.5%, respectively. Most current psychiatric comorbidity were major depressive disorder, suicidality and psychotic disorder ...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Psychiatric Comorbidity of Alcohol Dependent Patients Admitting in Chiang Mai Drug Dependence Treatment Center","attachmentId":76747945,"attachmentType":"pdf","work_url":"https://www.academia.edu/64950255/Psychiatric_Comorbidity_of_Alcohol_Dependent_Patients_Admitting_in_Chiang_Mai_Drug_Dependence_Treatment_Center","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/64950255/Psychiatric_Comorbidity_of_Alcohol_Dependent_Patients_Admitting_in_Chiang_Mai_Drug_Dependence_Treatment_Center"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="105937592" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/105937592/The_spectrum_of_substance_use_in_mood_and_anxiety_disorders">The spectrum of substance use in mood and anxiety disorders</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="42792267" href="https://independent.academia.edu/SSpagnolli">S. Spagnolli</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Comprehensive Psychiatry, 2005</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"The spectrum of substance use in mood and anxiety disorders","attachmentId":105268376,"attachmentType":"pdf","work_url":"https://www.academia.edu/105937592/The_spectrum_of_substance_use_in_mood_and_anxiety_disorders","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/105937592/The_spectrum_of_substance_use_in_mood_and_anxiety_disorders"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="16292337" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/16292337/Co_morbidity_of_substance_misuse_and_mental_illness_collaborative_study_COSMIC_">Co-morbidity of substance misuse and mental illness collaborative study (COSMIC)</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="35388732" href="https://independent.academia.edu/AdrianRenton">Adrian Renton</a></div><p class="ds-related-work--metadata ds2-5-body-xs">A study of the Prevalence and …, 2002</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Co-morbidity of substance misuse and mental illness collaborative study (COSMIC)","attachmentId":42560918,"attachmentType":"pdf","work_url":"https://www.academia.edu/16292337/Co_morbidity_of_substance_misuse_and_mental_illness_collaborative_study_COSMIC_","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/16292337/Co_morbidity_of_substance_misuse_and_mental_illness_collaborative_study_COSMIC_"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--sticky-ctas","attachmentId":87007985,"attachmentType":"pdf","workUrl":null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--sticky-ctas","attachmentId":87007985,"attachmentType":"pdf","workUrl":null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_87007985" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. 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href="https://www.academia.edu/99659930/Prevalence_of_anxiety_disorders_and_its_co_occurrence_with_substance_use_disorder_a_clinical_study"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="7" data-entity-id="60723894" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/60723894/Substance_misuse_and_psychiatric_illness_prospective_observational_study_using_the_general_practice_research_database">Substance misuse and psychiatric illness: prospective observational study using the general practice research database</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="32328274" 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