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<div id="sg_header"> <a class='slot-item' id='menu-slot-1' href='http://www.ucsf.edu/'>University of California San Francisco </a><a class='slot-item' id='menu-slot-2' href='http://www.ucsfhealth.org/'>UCSF Medical Center</a><a class='slot-item' id='menu-slot-3' href='http://surgery.ucsf.edu/'>UCSF Department of Surgery</a><a class='slot-item' id='menu-slot-4' href='http://medschool.ucsf.edu/'>UCSF School of Medicine</a> </div>   </div>   <div id="sg_topImageContainer">  <link type="text/css" href="/css/slideshow_header_styles.css" rel="stylesheet" /> <link type="text/css" href="/css/ucsf_compliant_banner.css" rel="stylesheet" /> <div id="slide-and-search-container">  <aside id='top_social_area' > <div class='social-icons social-follow'><h3>FOLLOW</h3><ul><li><a title='Follow Us on Twitter' href='https://twitter.com/UCSFPedSurgery' class='fontawesome-twitter'> </a></li><li><a title='Subscribe to our YouTube Channel' href='https://www.youtube.com/user/UCSFPediatricSurgery' 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href='https://pedsurglab.ucsf.edu/publications.aspx'>Publications</a></h2></li><li class='mega ' level='2'><h2 class='hasChildren'><a href='https://pedsurglab.ucsf.edu/news--events.aspx'>News & Events</a></h2><div class='dmain roundedDropdown'><div><ul class='level-3'><li class='menuBodyItem'><a href='https://pedsurglab.ucsf.edu/news--events/fetal-symposium-2014.aspx'>Fetal Symposium 2014</a></li></ul></div></div></li><li class='mega ' level='2'><h2 ><a href='https://pedsurglab.ucsf.edu/contact-us.aspx'>Contact Us</a></h2></li></ul></div> </div>     <div id="sg_breadcrumb_email"> <div id="sg_int_heading_top"> <div id="sg_breadcrumbDiv" style=""> </div> </div> </div>    <aside id='content_top_area'></aside>  <div id="sg_mainContent">  <div id="sg_centerSection">  <aside id='section_left_bar'> <div id="sg_leftMenus">  <div id="sg_leftMenu">   <div id="sg_leftBarEditableRegionDiv"> <div>  <div id='sg_leftBarEditableRegion' > </div><div style='clear:both;display:none;'>level</div> </div>  <div class='freeform-Box-Bottom'></div> </div> </div> </div> </aside>  <div id="sg_centerContent" >   <div id="sg_contentHeading" class='lab_front_heading'> <h1 class="sg_frontPageH1"> In Search of Innovative Solutions </h1> <div class='lab_content_textarea_top'> <p><img src="/media/1559659/fellow using chemical hood-1.jpg" src="/media/1559659/fellow using chemical hood-1.jpg" alt="fellow with chem-hood"/></p> <p>The pediatric surgery research effort is dedicated to helping improve the health of children. The problems of our small patients also become the motivation for investigators in the basic sciences to study mechanisms of disease and to develop new therapies to cure previously untreatable birth defects. Creating innovative solutions requires successful collaboration of diverse biological and physical science groups, and we continue to cultivate partnerships with many other outstanding research groups. The breadth of our research program spans <a href="http://pedsurglab.surgery.ucsf.edu/research.aspx#basic">basic science and translational research</a> to <a href="http://pedsurglab.surgery.ucsf.edu/research.aspx#innovation">innovation & device development</a> to <a href="http://pedsurglab.surgery.ucsf.edu/research.aspx#clinical">novel clinical therapies</a> in the area of fetal and pediatric surgery. </p> <p>Our clinical and basic science research programs have grown remarkably in productivity and funding in the past five years. We currently have more than $4 million in grants and awards for our faculty and fellows-a tremendous achievement after having limited funding for several years.</p> <p>Find out more about the <a href="https://www.pedsurg.ucsf.edu/" title="Pediatric Surgery">UCSF Division of Pediatric Surgery</a></p> <p>Find out more about the <a href="http://fetus.ucsfmedicalcenter.org/" title="Fetal Treatment Center">UCSF Fetal Treatment Center</a></p> </div> </div>   <div id="sg_bottomBoxContainer"> <div class="sg_hp_2col fp-pub-news"> <script language="javascript" type="text/javascript" xmlns:user="urn:my-scripts"> function goSelectYear(which) { var nhref = which.options[which.selectedIndex].value; var resId = document.getElementById("goResearch"); var resValue = resId.options[resId.selectedIndex].value; if (resValue != "" ) window.location.href = "?ysearch=" + nhref + "&rasearch=" + resValue; else window.location.href = "?ysearch=" + nhref; } function goSelectRA(which) { var nhref = which.options[which.selectedIndex].value; var resId = document.getElementById("goYear"); var resValue = resId.options[resId.selectedIndex].value; if (resValue != "" ) window.location.href = "?rasearch=" + nhref + "&ysearch=" + resValue; else window.location.href = "?rasearch=" + nhref; } </script><h2 id="sg_frontPageH2" xmlns:user="urn:my-scripts">Recent Publications</h2><table id="pubList" xmlns:user="urn:my-scripts"><tr><td><div class="fp_labs_pubs_list"><table class='pubs-table Pediatric-Surgery-Lab'><tr><td><ul class='fp_labs_pubs_items'><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/25147335' >Shear stress-activated Wnt-angiopoietin-2 signaling recapitulates vascular repair in zebrafish embryos. </a></div></li></ul></td></tr><tr><td><ul class='fp_labs_pubs_items'><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/24879814' >In utero depletion of fetal hematopoietic stem cells improves engraftment after neonatal transplantation in mice. </a></div></li></ul></td></tr><tr><td><ul class='fp_labs_pubs_items'><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/24805114' >Surgical site infections in neonates and infants: is antibiotic prophylaxis needed for longer than 24 h?. </a></div></li></ul></td></tr><tr><td><ul class='fp_labs_pubs_items'><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/24759226' >Maternal-fetal cellular trafficking: clinical implications and consequences. </a></div></li></ul></td></tr><tr><td><ul class='fp_labs_pubs_items'><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/24888831' >Outcomes of fetal intervention for primary hydrothorax. </a></div></li></ul></td></tr><tr><td><ul class='fp_labs_pubs_items'><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/24509084' >Memory regulatory T cells reside in human skin. </a></div></li></ul></td></tr><tr><td><ul class='fp_labs_pubs_items'><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/24415782' >Fetal intervention increases maternal T cell awareness of the foreign conceptus and can lead to immune-mediated fetal demise. </a></div></li></ul></td></tr><tr><td><ul class='fp_labs_pubs_items'><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/23770923' >Fetal production of growth factors and inflammatory mediators predicts pulmonary hypertension in congenital diaphragmatic hernia. </a></div></li></ul></td></tr><tr><td><ul class='fp_labs_pubs_items'><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/23845611' >Tumor metrics and morphology predict poor prognosis in prenatally diagnosed sacrococcygeal teratoma: a 25-year experience at a single institution. </a></div></li></ul></td></tr><tr><td><ul class='fp_labs_pubs_items'><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/23610372' >Direct and indirect antigen presentation lead to deletion of donor-specific T cells after in utero hematopoietic cell transplantation in mice. </a></div></li></ul></td></tr><tr><td><ul class='fp_labs_pubs_items'><li class='fp_labs_pubs_item_container' ><div class='fp_labs_pubs_title' ><a target='_blank' href='http://www.ncbi.nlm.nih.gov/pubmed/23395148' >Clinical implications of maternal-fetal cellular trafficking. </a></div></li></ul></td></tr></table></div></td></tr><tr><td class="fp_labs_pubs_viewall"><a href="https://pedsurglab.ucsf.edu/publications.aspx">View all Publications »</a></td></tr></table> </div> <div class="sg_hp_2col fp-pub-news"> <div id="middle_right_section"> <div id="middle_right_section_title"> <h2> News & Events </h2> </div> <table> <tr> <td> <ul class='news_frontpage_lab'> <li><a href='https://pedsurglab.ucsf.edu/news--events/ucsf-news.aspx?id=92769/Department-of-Surgery-staff-and-faculty-receive-2022-Chancellor-Awards-for-Diversity'>Department of Surgery staff and faculty receive 2022 Chancellor Awards for Diversity</a></li><li><a href='https://pedsurglab.ucsf.edu/news--events/ucsf-news.aspx?id=80731/Quoc-Hung-“Key”-Nguyen--MD-Receives-Two-Prestigious-Research-Awards-from-Association-for-Academic-Surgery'>Quoc-Hung “Key” Nguyen, MD Receives Two Prestigious Research Awards from Association for Academic Surgery</a></li><li><a href='https://pedsurglab.ucsf.edu/news--events/ucsf-news.aspx?id=79445/Pediatric-Surgeon-Benjamin-Padilla--MD-Honored-with-Exceptional-Physician-Award'>Pediatric Surgeon Benjamin Padilla, MD Honored with Exceptional Physician Award</a></li><li><a href='https://pedsurglab.ucsf.edu/news--events/ucsf-news.aspx?id=73877/Benjamin-Padilla-and-Michael-Harrison-Awarded-NIH-R03-for-Cryoanalgesia-Study'>Benjamin Padilla and Michael Harrison Awarded NIH R03 for Cryoanalgesia Study</a></li><li><a href='https://pedsurglab.ucsf.edu/news--events/ucsf-news.aspx?id=64382/UCSF-Researchers-Reappraise-Treatment-for-Gastroschisis--Shining-Light-on-Role-of-Immune-System'>UCSF Researchers Reappraise Treatment for Gastroschisis, Shining Light on Role of Immune System</a></li> </ul> <div class='news_frontpage_readmore' > <div class='news_frontpage_readmore'> <a href="https://pedsurglab.ucsf.edu/news--events.aspx">Read all news <span class="doublearray">»</span></a> </div> </div> </td> </tr> </table> </div> </div> </div>   <div id="slideout_programs_labs_panel" class='display-none'> <form> <div id="findAProgramLabLocal" xmlns:user="urn:my-scripts"><div class="findAProgramCloseButton"><a href="#"> </a></div><div class="findAProgramHeader"><div class="findAProgramColumnDiv robby">Programs</div><ul class='findAProgramPopoutUL'><li><a href='https://pedsurg.ucsf.edu/'>Pediatric Surgery</a></li><li><a href='#'></a></li><li><a href='https://pedctsurgery.ucsf.edu/'>Pediatric Cardiothoracic Surgery</a></li></ul></div><div class="findALabHeader"><div class="findAProgramColumnDiv robby3">Labs</div><ul class='findAProgramPopoutUL'><li><a href='https://pedsurglab.ucsf.edu/research/harrison-lab'>Harrison Lab</a></li><li><a href='#'></a></li><li><a href='#'></a></li><li><a href='#'></a></li></ul></div></div> </form> </div> <div id="slideout_programs_labs_panel_surgerywide" class='display-none'> <form> <div id="findAProgramLabSystemWide" xmlns:user="urn:my-scripts"><div class="findAProgramCloseButton"><a 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Preservation and Diabetic Foot</a></li><li><a href='https://geriatricsurgery.ucsf.edu/'>Center for Surgery in Older Adults</a></li><li><a href='https://colorectalsurgery.ucsf.edu/'>Colorectal Surgery</a></li><li><a href='https://endocrinesurgery.ucsf.edu/'>Endocrine Surgery</a></li><li><a href='https://eras.ucsf.edu/'>Enhanced Recovery After Surgery (ERAS)</a></li><li><a href='#'></a></li><li><a href='https://gisurgery.ucsf.edu/'>Gastrointestinal Surgery</a></li><li><a href='https://generalsurgery.ucsf.edu/'>General Surgery</a></li><li><a href='https://hpbsurgery.ucsf.edu/'>Hepatobiliary & Pancreatic Surgery</a></li><li><a href='https://liversource.ucsf.edu/'>LiverSource</a></li><li><a href='https://melanomasurgery.ucsf.edu/'>Melanoma Surgery</a></li><li><a href='https://ostomyhealthprofessionals.ucsf.edu/'>Ostomy Education Portal</a></li><li><a href='https://pedctsurgery.ucsf.edu/'>Pediatric Cardiothoracic Surgery</a></li><li><a href='https://pedsurg.ucsf.edu/'>Pediatric Surgery</a></li><li><a href='https://plasticsurgery.ucsf.edu/'>Plastic & Reconstructive Surgery</a></li><li><a href='https://roboticsurgery.ucsf.edu/'>Robotic Surgery</a></li><li><a href='https://sfva.ucsf.edu/'>San Francisco VA Medical Center</a></li><li><a href='#'></a></li><li><a href='https://top.ucsf.edu/'>Thoracic Oncology Program</a></li><li><a href='https://thoracicsurgery.ucsf.edu/'>Thoracic Surgery</a></li><li><a href='https://transplantsurgery.ucsf.edu/'>Transplant Surgery</a></li><li><a href='https://eastbaysurgery.ucsf.edu/'>UCSF East Bay Surgery Program</a></li><li><a href='https://vascularsurgery.ucsf.edu/'>Vascular & Endovascular Surgery</a></li><li><a href='https://zsfgsurgery.ucsf.edu/'>Zuckerberg San Francisco General</a></li><li><a href='https://settings.surgery.ucsf.edu/surgery-dropdown-headings/education-and-training'>EDUCATION AND TRAINING</a></li><li><a href='https://transplantfellowship.ucsf.edu/'>Abdominal Transplant Fellowship</a></li><li><a href='https://surgeryfap.ucsf.edu/'>Faculty Affairs & Development Portal</a></li><li><a href='https://medstudentsurgery.ucsf.edu/'>Medical Student Portal</a></li><li><a href='https://murielsteelesociety.ucsf.edu/'>Muriel Steele Society</a></li><li><a href='https://plasticsurgeryresidency.ucsf.edu/'>Plastic Surgery Residency</a></li><li><a href='https://surgeryresidentportal.ucsf.edu/'>Resident Portal</a></li><li><a href='https://surgeryresidentresearch.ucsf.edu/'>Resident Research</a></li><li><a href='https://npfellowship.ucsf.edu/'>Surgical & Critical Care NP Fellowship</a></li><li><a href='https://surgeryeducation.ucsf.edu/'>Surgery Education Portal</a></li><li><a href='https://staging42surgery.ucsf.edu/'>Surgery Research Portal</a></li><li><a href='https://surgicalskillslab.ucsf.edu/'>Surgical Skills Center</a></li><li><a href='https://thoracicsurgeryresidency.ucsf.edu/'>Thoracic Surgery Residency</a></li><li><a href='https://t32surgicaloncology.ucsf.edu/'>T32 Surgical Oncology</a></li><li><a href='https://t32transplantsurgery.ucsf.edu/'>T32 Research Training in Transplant Surgery</a></li><li><a href='https://vascularsurgeryresidency.ucsf.edu/'>Vascular Surgery Integrated Residency</a></li><li><a href='https://settings.surgery.ucsf.edu/surgery-dropdown-headings/research-websites'>RESEARCH WEBSITES</a></li><li><a href='#'></a></li><li><a href='https://raffailab.ucsf.edu/'>Atherosclerosis Research Lab</a></li><li><a href='https://surgerybiostat.ucsf.edu/'>Biostatistics Core</a></li><li><a href='https://cardiacbiomechanicslab.ucsf.edu/'>Cardiac Biomechanics Lab</a></li><li><a href='https://globalsurgery.ucsf.edu/'>Center for Global Surgery and Health Equity</a></li><li><a href='https://mindfulsurgeon.ucsf.edu/'>Center for Mindfulness in Surgery</a></li><li><a href='https://livertissueengineering.ucsf.edu/'>Chang Laboratory for Liver Tissue Engineering</a></li><li><a href='https://contelab.ucsf.edu/'>Conte Lab</a></li><li><a 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