CINXE.COM

<!DOCTYPE html> <html lang="en" xmlns:fb="http://www.facebook.com/2008/fbml" class="wf-loading"> <head prefix="og: https://ogp.me/ns# fb: https://ogp.me/ns/fb# academia: https://ogp.me/ns/fb/academia#"> <meta charset="utf-8"> <meta name=viewport content="width=device-width, initial-scale=1"> <meta rel="search" type="application/opensearchdescription+xml" href="/open_search.xml" title="Academia.edu"> <title>Leukemia Research Papers - Academia.edu</title>  <link href="//a.academia-assets.com/images/favicons/favicon-production.ico" rel="shortcut icon" type="image/vnd.microsoft.icon"> <link rel="apple-touch-icon" sizes="57x57" href="//a.academia-assets.com/images/favicons/apple-touch-icon-57x57.png"> <link rel="apple-touch-icon" sizes="60x60" href="//a.academia-assets.com/images/favicons/apple-touch-icon-60x60.png"> <link rel="apple-touch-icon" sizes="72x72" href="//a.academia-assets.com/images/favicons/apple-touch-icon-72x72.png"> <link rel="apple-touch-icon" sizes="76x76" href="//a.academia-assets.com/images/favicons/apple-touch-icon-76x76.png"> <link rel="apple-touch-icon" sizes="114x114" href="//a.academia-assets.com/images/favicons/apple-touch-icon-114x114.png"> <link rel="apple-touch-icon" sizes="120x120" href="//a.academia-assets.com/images/favicons/apple-touch-icon-120x120.png"> <link rel="apple-touch-icon" sizes="144x144" href="//a.academia-assets.com/images/favicons/apple-touch-icon-144x144.png"> <link rel="apple-touch-icon" sizes="152x152" href="//a.academia-assets.com/images/favicons/apple-touch-icon-152x152.png"> <link rel="apple-touch-icon" sizes="180x180" href="//a.academia-assets.com/images/favicons/apple-touch-icon-180x180.png"> <link rel="icon" type="image/png" href="//a.academia-assets.com/images/favicons/favicon-32x32.png" sizes="32x32"> <link rel="icon" type="image/png" href="//a.academia-assets.com/images/favicons/favicon-194x194.png" sizes="194x194"> <link rel="icon" type="image/png" href="//a.academia-assets.com/images/favicons/favicon-96x96.png" sizes="96x96"> <link rel="icon" type="image/png" href="//a.academia-assets.com/images/favicons/android-chrome-192x192.png" sizes="192x192"> <link rel="icon" type="image/png" href="//a.academia-assets.com/images/favicons/favicon-16x16.png" sizes="16x16"> <link rel="manifest" href="//a.academia-assets.com/images/favicons/manifest.json"> <meta name="msapplication-TileColor" content="#2b5797"> <meta name="msapplication-TileImage" content="//a.academia-assets.com/images/favicons/mstile-144x144.png"> <meta name="theme-color" content="#ffffff"> <script> window.performance && window.performance.measure && window.performance.measure("Time To First Byte", "requestStart", "responseStart"); </script> <script> (function() { if (!window.URLSearchParams || !window.history || !window.history.replaceState) { return; } var searchParams = new URLSearchParams(window.location.search); var paramsToDelete = [ 'fs', 'sm', 'swp', 'iid', 'nbs', 'rcc', // related content category 'rcpos', // related content carousel position 'rcpg', // related carousel page 'rchid', // related content hit id 'f_ri', // research interest id, for SEO tracking 'f_fri', // featured research interest, for SEO tracking (param key without value) 'f_rid', // from research interest directory for SEO tracking 'f_loswp', // from research interest pills on LOSWP sidebar for SEO tracking 'rhid', // referrring hit id ]; if (paramsToDelete.every((key) => searchParams.get(key) === null)) { return; } paramsToDelete.forEach((key) => { searchParams.delete(key); }); var cleanUrl = new URL(window.location.href); cleanUrl.search = searchParams.toString(); history.replaceState({}, document.title, cleanUrl); })(); </script> <script async src="https://www.googletagmanager.com/gtag/js?id=G-5VKX33P2DS"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-5VKX33P2DS', { cookie_domain: 'academia.edu', send_page_view: false, }); gtag('event', 'page_view', { 'controller': "by_tag", 'action': "show_one", 'controller_action': 'by_tag#show_one', 'logged_in': 'false', 'edge': 'unknown', // Send nil if there is no A/B test bucket, in case some records get logged // with missing data - that way we can distinguish between the two cases. // ab_test_bucket should be of the form <ab_test_name>:<bucket> 'ab_test_bucket': null, }) </script> <script type="text/javascript"> window.sendUserTiming = function(timingName) { if (!(window.performance && window.performance.measure)) return; var entries = window.performance.getEntriesByName(timingName, "measure"); if (entries.length !== 1) return; var timingValue = Math.round(entries[0].duration); gtag('event', 'timing_complete', { name: timingName, value: timingValue, event_category: 'User-centric', }); }; window.sendUserTiming("Time To First Byte"); </script> <meta name="csrf-param" content="authenticity_token" /> <meta name="csrf-token" content="82fenuiMMd4bP4B5NlZBX0VaULFmTe5SRNJTTWwQxPK+eanrtcoYksZ2gZdVQo7HbBjB7I6SANz07DPMr0vh3A==" /> <link href="/Documents/in/Leukemia?after=50%2C32936482" rel="next" /><link crossorigin="" href="https://fonts.gstatic.com/" rel="preconnect" /><link href="https://fonts.googleapis.com/css2?family=DM+Sans:ital,opsz,wght@0,9..40,100..1000;1,9..40,100..1000&family=Gupter:wght@400;500;700&family=IBM+Plex+Mono:wght@300;400&family=Material+Symbols+Outlined:opsz,wght,FILL,GRAD@20,400,0,0&display=swap" rel="stylesheet" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/common-10fa40af19d25203774df2d4a03b9b5771b45109c2304968038e88a81d1215c5.css" /> <meta name="description" content="View Leukemia Research Papers on Academia.edu for free." /> <meta name="google-site-verification" content="bKJMBZA7E43xhDOopFZkssMMkBRjvYERV-NaN4R6mrs" /> <script> var $controller_name = 'by_tag'; var $action_name = "show_one"; var $rails_env = 'production'; var $app_rev = '92477ec68c09d28ae4730a4143c926f074776319'; var $domain = 'academia.edu'; var $app_host = "academia.edu"; var $asset_host = "academia-assets.com"; var $start_time = new Date().getTime(); var $recaptcha_key = "6LdxlRMTAAAAADnu_zyLhLg0YF9uACwz78shpjJB"; var $recaptcha_invisible_key = "6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj"; var $disableClientRecordHit = false; </script> <script> window.Aedu = { hit_data: null }; window.Aedu.SiteStats = {"premium_universities_count":15276,"monthly_visitors":"113 million","monthly_visitor_count":113458213,"monthly_visitor_count_in_millions":113,"user_count":277573359,"paper_count":55203019,"paper_count_in_millions":55,"page_count":432000000,"page_count_in_millions":432,"pdf_count":16500000,"pdf_count_in_millions":16}; window.Aedu.serverRenderTime = new Date(1732839943000); window.Aedu.timeDifference = new Date().getTime() - 1732839943000; window.Aedu.isUsingCssV1 = false; window.Aedu.enableLocalization = true; window.Aedu.activateFullstory = false; window.Aedu.serviceAvailability = { status: {"attention_db":"on","bibliography_db":"on","contacts_db":"on","email_db":"on","indexability_db":"on","mentions_db":"on","news_db":"on","notifications_db":"on","offsite_mentions_db":"on","redshift":"on","redshift_exports_db":"on","related_works_db":"on","ring_db":"on","user_tests_db":"on"}, serviceEnabled: function(service) { return this.status[service] === "on"; }, readEnabled: function(service) { return this.serviceEnabled(service) || this.status[service] === "read_only"; }, }; window.Aedu.viewApmTrace = function() { // Check if x-apm-trace-id meta tag is set, and open the trace in APM // in a new window if it is. var apmTraceId = document.head.querySelector('meta[name="x-apm-trace-id"]'); if (apmTraceId) { var traceId = apmTraceId.content; // Use trace ID to construct URL, an example URL looks like: // https://app.datadoghq.com/apm/traces?query=trace_id%31298410148923562634 var apmUrl = 'https://app.datadoghq.com/apm/traces?query=trace_id%3A' + traceId; window.open(apmUrl, '_blank'); } }; </script>  <link href="https://fonts.googleapis.com/css?family=Roboto:100,100i,300,300i,400,400i,500,500i,700,700i,900,900i" rel="stylesheet"> <link href="//maxcdn.bootstrapcdn.com/font-awesome/4.3.0/css/font-awesome.min.css" rel="stylesheet"> <link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/libraries-a9675dcb01ec4ef6aa807ba772c7a5a00c1820d3ff661c1038a20f80d06bb4e4.css" /> <link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/academia-bdb9e8c097f01e611f2fc5e2f1a9dc599beede975e2ae5629983543a1726e947.css" /> <link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system_legacy-056a9113b9a0f5343d013b29ee1929d5a18be35fdcdceb616600b4db8bd20054.css" /> <script src="//a.academia-assets.com/assets/webpack_bundles/runtime-bundle-005434038af4252ca37c527588411a3d6a0eabb5f727fac83f8bbe7fd88d93bb.js"></script> <script src="//a.academia-assets.com/assets/webpack_bundles/webpack_libraries_and_infrequently_changed.wjs-bundle-bae13f9b51961d5f1e06008e39e31d0138cb31332e8c2e874c6d6a250ec2bb14.js"></script> <script src="//a.academia-assets.com/assets/webpack_bundles/core_webpack.wjs-bundle-19a25d160d01bde427443d06cd6b810c4c92c6026e7cb31519e06313eb24ed90.js"></script> <script src="//a.academia-assets.com/assets/webpack_bundles/sentry.wjs-bundle-5fe03fddca915c8ba0f7edbe64c194308e8ce5abaed7bffe1255ff37549c4808.js"></script> <script> jade = window.jade || {}; jade.helpers = window.$h; jade._ = window._; </script>  <script id="tag-manager-head-root">(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start': new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0], j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src= 'https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f); })(window,document,'script','dataLayer_old','GTM-5G9JF7Z');</script>  <script> window.gptadslots = []; window.googletag = window.googletag || {}; window.googletag.cmd = window.googletag.cmd || []; </script> <script type="text/javascript"> // TODO(jacob): This should be defined, may be rare load order problem. // Checking if null is just a quick fix, will default to en if unset. // Better fix is to run this immedietely after I18n is set. if (window.I18n != null) { I18n.defaultLocale = "en"; I18n.locale = "en"; I18n.fallbacks = true; } </script> <link rel="canonical" href="https://www.academia.edu/Documents/in/Leukemia" /> </head>   <body class='c-by_tag a-show_one logged_out u-bgColorWhite'>  <div id="fb-root"></div><script>window.fbAsyncInit = function() { FB.init({ appId: "2369844204", version: "v8.0", status: true, cookie: true, xfbml: true }); // Additional initialization code. if (window.InitFacebook) { // facebook.ts already loaded, set it up. window.InitFacebook(); } else { // Set a flag for facebook.ts to find when it loads. window.academiaAuthReadyFacebook = true; } };</script><script>window.fbAsyncLoad = function() { // Protection against double calling of this function if (window.FB) { return; } (function(d, s, id){ var js, fjs = d.getElementsByTagName(s)[0]; if (d.getElementById(id)) {return;} js = d.createElement(s); js.id = id; js.src = "//connect.facebook.net/en_US/sdk.js"; fjs.parentNode.insertBefore(js, fjs); }(document, 'script', 'facebook-jssdk')); } if (!window.defer_facebook) { // Autoload if not deferred window.fbAsyncLoad(); } else { // Defer loading by 5 seconds setTimeout(function() { window.fbAsyncLoad(); }, 5000); }</script> <div id="google-root"></div><script>window.loadGoogle = function() { if (window.InitGoogle) { // google.ts already loaded, set it up. window.InitGoogle("331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b"); } else { // Set a flag for google.ts to use when it loads. window.GoogleClientID = "331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b"; } };</script><script>window.googleAsyncLoad = function() { // Protection against double calling of this function (function(d) { var js; var id = 'google-jssdk'; var ref = d.getElementsByTagName('script')[0]; if (d.getElementById(id)) { return; } js = d.createElement('script'); js.id = id; js.async = true; js.onload = loadGoogle; js.src = "https://accounts.google.com/gsi/client" ref.parentNode.insertBefore(js, ref); }(document)); } if (!window.defer_google) { // Autoload if not deferred window.googleAsyncLoad(); } else { // Defer loading by 5 seconds setTimeout(function() { window.googleAsyncLoad(); }, 5000); }</script> <div id="tag-manager-body-root">  <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-5G9JF7Z" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript>   <script> window.addEventListener('load', function() { if (document.querySelector('input[name="commit"]')) { document.querySelector('input[name="commit"]').addEventListener('click', function() { gtag('event', 'click', { event_category: 'button', event_label: 'Log In' }) }) } }); </script> </div> <script>var _comscore = _comscore || []; _comscore.push({ c1: "2", c2: "26766707" }); (function() { var s = document.createElement("script"), el = document.getElementsByTagName("script")[0]; s.async = true; s.src = (document.location.protocol == "https:" ? "https://sb" : "http://b") + ".scorecardresearch.com/beacon.js"; el.parentNode.insertBefore(s, el); })();</script><img src="https://sb.scorecardresearch.com/p?c1=2&c2=26766707&cv=2.0&cj=1" style="position: absolute; visibility: hidden" /> <div id='react-modal'></div> <div class='DesignSystem'> <a class='u-showOnFocus' href='#site'> Skip to main content </a> </div> <div id="upgrade_ie_banner" style="display: none;"><p>Academia.edu no longer supports Internet Explorer.</p><p>To browse Academia.edu and the wider internet faster and more securely, please take a few seconds to <a href="https://www.academia.edu/upgrade-browser">upgrade your browser</a>.</p></div><script>// Show this banner for all versions of IE if (!!window.MSInputMethodContext || /(MSIE)/.test(navigator.userAgent)) { document.getElementById('upgrade_ie_banner').style.display = 'block'; }</script> <div class="DesignSystem bootstrap ShrinkableNav no-sm no-md"><div class="navbar navbar-default main-header"><div class="container-wrapper" id="main-header-container"><div class="container"><div class="navbar-header"><div class="nav-left-wrapper u-mt0x"><div class="nav-logo"><a data-main-header-link-target="logo_home" href="https://www.academia.edu/"><img class="visible-xs-inline-block" style="height: 24px;" alt="Academia.edu" src="//a.academia-assets.com/images/academia-logo-redesign-2015-A.svg" width="24" height="24" /><img width="145.2" height="18" class="hidden-xs" style="height: 24px;" alt="Academia.edu" src="//a.academia-assets.com/images/academia-logo-redesign-2015.svg" /></a></div><div class="nav-search"><div class="SiteSearch-wrapper select2-no-default-pills"><form class="js-SiteSearch-form DesignSystem" action="https://www.academia.edu/search" accept-charset="UTF-8" method="get"><input name="utf8" type="hidden" value="✓" autocomplete="off" /><i class="SiteSearch-icon fa fa-search u-fw700 u-positionAbsolute u-tcGrayDark"></i><input class="js-SiteSearch-form-input SiteSearch-form-input form-control" data-main-header-click-target="search_input" name="q" placeholder="Search" type="text" value="" /></form></div></div></div><div class="nav-right-wrapper pull-right"><ul class="NavLinks js-main-nav list-unstyled"><li class="NavLinks-link"><a class="js-header-login-url Button Button--inverseGray Button--sm u-mb4x" id="nav_log_in" rel="nofollow" href="https://www.academia.edu/login">Log In</a></li><li class="NavLinks-link u-p0x"><a class="Button Button--inverseGray Button--sm u-mb4x" rel="nofollow" href="https://www.academia.edu/signup">Sign Up</a></li></ul><button class="hidden-lg hidden-md hidden-sm u-ml4x navbar-toggle collapsed" data-target=".js-mobile-header-links" data-toggle="collapse" type="button"><span class="icon-bar"></span><span class="icon-bar"></span><span class="icon-bar"></span></button></div></div><div class="collapse navbar-collapse js-mobile-header-links"><ul class="nav navbar-nav"><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/login">Log In</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/signup">Sign Up</a></li><li class="u-borderColorGrayLight u-borderBottom1 js-mobile-nav-expand-trigger"><a href="#">more&nbsp<span class="caret"></span></a></li><li><ul class="js-mobile-nav-expand-section nav navbar-nav u-m0x collapse"><li class="u-borderColorGrayLight u-borderBottom1"><a rel="false" href="https://www.academia.edu/about">About</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/press">Press</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://medium.com/@academia">Blog</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="false" href="https://www.academia.edu/documents">Papers</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/terms">Terms</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/privacy">Privacy</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/copyright">Copyright</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/hiring"><i class="fa fa-briefcase"></i> We're Hiring!</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://support.academia.edu/"><i class="fa fa-question-circle"></i> Help Center</a></li><li class="js-mobile-nav-collapse-trigger u-borderColorGrayLight u-borderBottom1 dropup" style="display:none"><a href="#">less&nbsp<span class="caret"></span></a></li></ul></li></ul></div></div></div><script>(function(){ var $moreLink = $(".js-mobile-nav-expand-trigger"); var $lessLink = $(".js-mobile-nav-collapse-trigger"); var $section = $('.js-mobile-nav-expand-section'); $moreLink.click(function(ev){ ev.preventDefault(); $moreLink.hide(); $lessLink.show(); $section.collapse('show'); }); $lessLink.click(function(ev){ ev.preventDefault(); $moreLink.show(); $lessLink.hide(); $section.collapse('hide'); }); })() if ($a.is_logged_in() || false) { new Aedu.NavigationController({ el: '.js-main-nav', showHighlightedNotification: false }); } else { $(".js-header-login-url").attr("href", $a.loginUrlWithRedirect()); } Aedu.autocompleteSearch = new AutocompleteSearch({el: '.js-SiteSearch-form'});</script></div></div> <div id='site' class='fixed'> <div id="content" class="clearfix"> <script>document.addEventListener('DOMContentLoaded', function(){ var $dismissible = $(".dismissible_banner"); $dismissible.click(function(ev) { $dismissible.hide(); }); });</script> <div class="DesignSystem" style="margin-top:-40px"><div class="PageHeader"><div class="container"><div class="row"><style type="text/css">.sor-abstract { display: -webkit-box; overflow: hidden; text-overflow: ellipsis; -webkit-line-clamp: 3; -webkit-box-orient: vertical; }</style><div class="col-xs-12 clearfix"><div class="u-floatLeft"><h1 class="PageHeader-title u-m0x u-fs30">Leukemia</h1><div class="u-tcGrayDark">12,061 Followers</div><div class="u-tcGrayDark u-mt2x">Recent papers in <b>Leukemia</b></div></div></div></div></div></div><div class="TabbedNavigation"><div class="container"><div class="row"><div class="col-xs-12 clearfix"><ul class="nav u-m0x u-p0x list-inline u-displayFlex"><li class="active"><a href="https://www.academia.edu/Documents/in/Leukemia">Top Papers</a></li><li><a href="https://www.academia.edu/Documents/in/Leukemia/MostCited">Most Cited Papers</a></li><li><a href="https://www.academia.edu/Documents/in/Leukemia/MostDownloaded">Most Downloaded Papers</a></li><li><a href="https://www.academia.edu/Documents/in/Leukemia/MostRecent">Newest Papers</a></li><li><a class="" href="https://www.academia.edu/People/Leukemia">People</a></li></ul></div><style type="text/css">ul.nav{flex-direction:row}@media(max-width: 567px){ul.nav{flex-direction:column}.TabbedNavigation li{max-width:100%}.TabbedNavigation li.active{background-color:var(--background-grey, #dddde2)}.TabbedNavigation li.active:before,.TabbedNavigation li.active:after{display:none}}</style></div></div></div><div class="container"><div class="row"><div class="col-xs-12"><div class="u-displayFlex"><div class="u-flexGrow1"><div class="works"><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_11231053" data-work_id="11231053" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/11231053/CD5_provides_viability_signals_to_B_cells_from_a_subset_of_B_CLL_patients_by_a_mechanism_that_involves_PKC">CD5 provides viability signals to B cells from a subset of B-CLL patients by a mechanism that involves PKC</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">B-chronic lymphocytic leukaemia (B-CLL) is a heterogeneous disease characterized by an accumulation of B lymphocytes expressing CD5. To date, the biological significance of this molecule in B-CLL B cells remains to be elucidated. In this... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_11231053" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">B-chronic lymphocytic leukaemia (B-CLL) is a heterogeneous disease characterized by an accumulation of B lymphocytes expressing CD5. To date, the biological significance of this molecule in B-CLL B cells remains to be elucidated. In this study, we have analysed the functional consequences of the binding of an anti-CD5 antibody on B-CLL B cells. To this purpose, we have measured the percentage of viability of B-CLL B cells in the presence or in the absence of anti-CD5 antibodies and also examined some of the biochemical events downstream the CD5-signalling. We demonstrate that anti-CD5 induces phosphorylation of protein tyrosine kinases and protein kinase C (PKC), while no activation of Akt/PKB and MAPKs is detected. This signalling cascade results in viability in a group of patients in which we observe an increase of Mcl-1 levels, whereas the levels of bcl-2, bcl-xL and XIAP do not change. We also report that this pathway leads to IL-10 production, an immunoregulatory cytokine that might act as an autocrine growth factor for leukaemic B cells. Inhibition of PKC prevents the induction of Mcl-1 and IL-10, suggesting that the activation of PKC plays an important role in the CD5-mediated survival signals in B cells from a subset of B-CLL patients.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/11231053" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="2e69406043b9bb28ccfd770f387b44e8" rel="nofollow" data-download="{"attachment_id":46805109,"asset_id":11231053,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46805109/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="27139427" href="https://independent.academia.edu/PalomaPerezAciego">Paloma Perez-Aciego</a><script data-card-contents-for-user="27139427" type="text/json">{"id":27139427,"first_name":"Paloma","last_name":"Perez-Aciego","domain_name":"independent","page_name":"PalomaPerezAciego","display_name":"Paloma Perez-Aciego","profile_url":"https://independent.academia.edu/PalomaPerezAciego?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_11231053 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="11231053"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 11231053, container: ".js-paper-rank-work_11231053", }); });</script></li><li class="js-percentile-work_11231053 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 11231053; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_11231053"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_11231053 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="11231053"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 11231053; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=11231053]").text(description); $(".js-view-count-work_11231053").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_11231053").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="11231053"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="24731" href="https://www.academia.edu/Documents/in/Apoptosis">Apoptosis</a>, <script data-card-contents-for-ri="24731" type="text/json">{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="38831" href="https://www.academia.edu/Documents/in/Signal_Transduction">Signal Transduction</a>, <script data-card-contents-for-ri="38831" type="text/json">{"id":38831,"name":"Signal Transduction","url":"https://www.academia.edu/Documents/in/Signal_Transduction?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="140106" href="https://www.academia.edu/Documents/in/Protein_Tyrosine_Kinase">Protein Tyrosine Kinase</a><script data-card-contents-for-ri="140106" type="text/json">{"id":140106,"name":"Protein Tyrosine Kinase","url":"https://www.academia.edu/Documents/in/Protein_Tyrosine_Kinase?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=11231053]'), work: {"id":11231053,"title":"CD5 provides viability signals to B cells from a subset of B-CLL patients by a mechanism that involves PKC","created_at":"2015-03-03T07:42:01.145-08:00","url":"https://www.academia.edu/11231053/CD5_provides_viability_signals_to_B_cells_from_a_subset_of_B_CLL_patients_by_a_mechanism_that_involves_PKC?f_ri=14109","dom_id":"work_11231053","summary":"B-chronic lymphocytic leukaemia (B-CLL) is a heterogeneous disease characterized by an accumulation of B lymphocytes expressing CD5. To date, the biological significance of this molecule in B-CLL B cells remains to be elucidated. In this study, we have analysed the functional consequences of the binding of an anti-CD5 antibody on B-CLL B cells. To this purpose, we have measured the percentage of viability of B-CLL B cells in the presence or in the absence of anti-CD5 antibodies and also examined some of the biochemical events downstream the CD5-signalling. We demonstrate that anti-CD5 induces phosphorylation of protein tyrosine kinases and protein kinase C (PKC), while no activation of Akt/PKB and MAPKs is detected. This signalling cascade results in viability in a group of patients in which we observe an increase of Mcl-1 levels, whereas the levels of bcl-2, bcl-xL and XIAP do not change. We also report that this pathway leads to IL-10 production, an immunoregulatory cytokine that might act as an autocrine growth factor for leukaemic B cells. Inhibition of PKC prevents the induction of Mcl-1 and IL-10, suggesting that the activation of PKC plays an important role in the CD5-mediated survival signals in B cells from a subset of B-CLL patients.","downloadable_attachments":[{"id":46805109,"asset_id":11231053,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":27139427,"first_name":"Paloma","last_name":"Perez-Aciego","domain_name":"independent","page_name":"PalomaPerezAciego","display_name":"Paloma Perez-Aciego","profile_url":"https://independent.academia.edu/PalomaPerezAciego?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis?f_ri=14109","nofollow":false},{"id":38831,"name":"Signal Transduction","url":"https://www.academia.edu/Documents/in/Signal_Transduction?f_ri=14109","nofollow":false},{"id":140106,"name":"Protein Tyrosine Kinase","url":"https://www.academia.edu/Documents/in/Protein_Tyrosine_Kinase?f_ri=14109","nofollow":false},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109"},{"id":678853,"name":"B Lymphocytes","url":"https://www.academia.edu/Documents/in/B_Lymphocytes?f_ri=14109"},{"id":951344,"name":"Growth Factor","url":"https://www.academia.edu/Documents/in/Growth_Factor?f_ri=14109"},{"id":1157148,"name":"Cell Survival","url":"https://www.academia.edu/Documents/in/Cell_Survival?f_ri=14109"},{"id":1924712,"name":"Interleukin","url":"https://www.academia.edu/Documents/in/Interleukin?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_20080336" data-work_id="20080336" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/20080336/Intensified_therapy_in_acute_lymphoblastic_and_acute_undifferentiated_leukemia_in_adults">Intensified therapy in acute lymphoblastic and acute undifferentiated leukemia in adults</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">One hundred seventy adult patients with acute lymphoblastic leukemia (ALL) or acute undifferentiated leukemia (AUL) were entered into a prospective multicenter therapy trial at 25 hospitals. The aim of the trial was to improve remission... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_20080336" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">One hundred seventy adult patients with acute lymphoblastic leukemia (ALL) or acute undifferentiated leukemia (AUL) were entered into a prospective multicenter therapy trial at 25 hospitals. The aim of the trial was to improve remission duration by using a modified form of an intensified induction regimen that was successful in childhood ALL, to define immunologic subtypes of ALL by use of cell-surface markers, and to extract other possible prognostic factors. The overall complete remission rate was 77.8%. The median overall survival time was 26 months, being 4 months for nonresponders and 32 months for responders. The median remission duration for the 126 patients with complete remission was 20 months. Prognostically favorable factors for remission duration were response to chemotherapy within 4 weeks, age less than 35 years, a low initial leukocyte count, and the immunologic subtypes c-ALL with early response to therapy and T-ALL, where 61% and 58%, respectively, are still in comp...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/20080336" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="647ca49817d6fba659138f14b9be6e8c" rel="nofollow" data-download="{"attachment_id":41249728,"asset_id":20080336,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/41249728/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="41080518" href="https://uthsc.academia.edu/ArthurNienhuis">Arthur Nienhuis</a><script data-card-contents-for-user="41080518" type="text/json">{"id":41080518,"first_name":"Arthur","last_name":"Nienhuis","domain_name":"uthsc","page_name":"ArthurNienhuis","display_name":"Arthur Nienhuis","profile_url":"https://uthsc.academia.edu/ArthurNienhuis?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_20080336 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="20080336"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 20080336, container: ".js-paper-rank-work_20080336", }); });</script></li><li class="js-percentile-work_20080336 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 20080336; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_20080336"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_20080336 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="20080336"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 20080336; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=20080336]").text(description); $(".js-view-count-work_20080336").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_20080336").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="20080336"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">10</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a>, <script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="100732" href="https://www.academia.edu/Documents/in/Blood">Blood</a><script data-card-contents-for-ri="100732" type="text/json">{"id":100732,"name":"Blood","url":"https://www.academia.edu/Documents/in/Blood?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=20080336]'), work: {"id":20080336,"title":"Intensified therapy in acute lymphoblastic and acute undifferentiated leukemia in adults","created_at":"2016-01-07T05:48:58.029-08:00","url":"https://www.academia.edu/20080336/Intensified_therapy_in_acute_lymphoblastic_and_acute_undifferentiated_leukemia_in_adults?f_ri=14109","dom_id":"work_20080336","summary":"One hundred seventy adult patients with acute lymphoblastic leukemia (ALL) or acute undifferentiated leukemia (AUL) were entered into a prospective multicenter therapy trial at 25 hospitals. The aim of the trial was to improve remission duration by using a modified form of an intensified induction regimen that was successful in childhood ALL, to define immunologic subtypes of ALL by use of cell-surface markers, and to extract other possible prognostic factors. The overall complete remission rate was 77.8%. The median overall survival time was 26 months, being 4 months for nonresponders and 32 months for responders. The median remission duration for the 126 patients with complete remission was 20 months. Prognostically favorable factors for remission duration were response to chemotherapy within 4 weeks, age less than 35 years, a low initial leukocyte count, and the immunologic subtypes c-ALL with early response to therapy and T-ALL, where 61% and 58%, respectively, are still in comp...","downloadable_attachments":[{"id":41249728,"asset_id":20080336,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":41080518,"first_name":"Arthur","last_name":"Nienhuis","domain_name":"uthsc","page_name":"ArthurNienhuis","display_name":"Arthur Nienhuis","profile_url":"https://uthsc.academia.edu/ArthurNienhuis?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=14109","nofollow":false},{"id":100732,"name":"Blood","url":"https://www.academia.edu/Documents/in/Blood?f_ri=14109","nofollow":false},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109"},{"id":280237,"name":"T lymphocytes","url":"https://www.academia.edu/Documents/in/T_lymphocytes?f_ri=14109"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=14109"},{"id":546419,"name":"Age Factors","url":"https://www.academia.edu/Documents/in/Age_Factors?f_ri=14109"},{"id":678853,"name":"B Lymphocytes","url":"https://www.academia.edu/Documents/in/B_Lymphocytes?f_ri=14109"},{"id":1212103,"name":"Antineoplastic Agents","url":"https://www.academia.edu/Documents/in/Antineoplastic_Agents?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_79703022" data-work_id="79703022" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/79703022/Rare_tetraploidy_with_large_5q_deletion_in_acute_myeloid_leukemia_with_myelodysplasia_related_changes_AML_MRC_">Rare tetraploidy with large 5q deletion in acute myeloid leukemia with myelodysplasia-related changes (AML-MRC)</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/79703022" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="0bc4c5e7900413e28d8af5576aed66b9" rel="nofollow" data-download="{"attachment_id":86328034,"asset_id":79703022,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/86328034/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="41894125" href="https://independent.academia.edu/KIndrak">K. Indrak</a><script data-card-contents-for-user="41894125" type="text/json">{"id":41894125,"first_name":"K.","last_name":"Indrak","domain_name":"independent","page_name":"KIndrak","display_name":"K. Indrak","profile_url":"https://independent.academia.edu/KIndrak?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_79703022 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="79703022"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 79703022, container: ".js-paper-rank-work_79703022", }); });</script></li><li class="js-percentile-work_79703022 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 79703022; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_79703022"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_79703022 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="79703022"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 79703022; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=79703022]").text(description); $(".js-view-count-work_79703022").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_79703022").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="79703022"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">7</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="59057" href="https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia">Acute Myeloid Leukemia</a>, <script data-card-contents-for-ri="59057" type="text/json">{"id":59057,"name":"Acute Myeloid Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="65882" href="https://www.academia.edu/Documents/in/Fluorescence_in_situ_hybridization">Fluorescence in situ hybridization</a>, <script data-card-contents-for-ri="65882" type="text/json">{"id":65882,"name":"Fluorescence in situ hybridization","url":"https://www.academia.edu/Documents/in/Fluorescence_in_situ_hybridization?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a><script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=79703022]'), work: {"id":79703022,"title":"Rare tetraploidy with large 5q deletion in acute myeloid leukemia with myelodysplasia-related changes (AML-MRC)","created_at":"2022-05-22T23:06:58.749-07:00","url":"https://www.academia.edu/79703022/Rare_tetraploidy_with_large_5q_deletion_in_acute_myeloid_leukemia_with_myelodysplasia_related_changes_AML_MRC_?f_ri=14109","dom_id":"work_79703022","summary":null,"downloadable_attachments":[{"id":86328034,"asset_id":79703022,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":41894125,"first_name":"K.","last_name":"Indrak","domain_name":"independent","page_name":"KIndrak","display_name":"K. Indrak","profile_url":"https://independent.academia.edu/KIndrak?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":59057,"name":"Acute Myeloid Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia?f_ri=14109","nofollow":false},{"id":65882,"name":"Fluorescence in situ hybridization","url":"https://www.academia.edu/Documents/in/Fluorescence_in_situ_hybridization?f_ri=14109","nofollow":false},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109","nofollow":false},{"id":571886,"name":"Immunophenotyping","url":"https://www.academia.edu/Documents/in/Immunophenotyping?f_ri=14109"},{"id":3208276,"name":"Chromosome deletion","url":"https://www.academia.edu/Documents/in/Chromosome_deletion?f_ri=14109"},{"id":3541888,"name":"Myelodysplastic syndromes","url":"https://www.academia.edu/Documents/in/Myelodysplastic_syndromes?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_49670567" data-work_id="49670567" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/49670567/Detection_of_bcrabl_fusion_mRNA_in_samples_of_whole_unfractionated_blood">Detection of bcrabl fusion mRNA in samples of whole, unfractionated blood</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/49670567" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="aea2f704a62ea6a5eec116906793a93f" rel="nofollow" data-download="{"attachment_id":67957731,"asset_id":49670567,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/67957731/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="186741368" href="https://independent.academia.edu/CuddyKevin">Kevin Cuddy</a><script data-card-contents-for-user="186741368" type="text/json">{"id":186741368,"first_name":"Kevin","last_name":"Cuddy","domain_name":"independent","page_name":"CuddyKevin","display_name":"Kevin Cuddy","profile_url":"https://independent.academia.edu/CuddyKevin?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_49670567 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="49670567"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 49670567, container: ".js-paper-rank-work_49670567", }); });</script></li><li class="js-percentile-work_49670567 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 49670567; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_49670567"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_49670567 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="49670567"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 49670567; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=49670567]").text(description); $(".js-view-count-work_49670567").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_49670567").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="49670567"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">12</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="2513" href="https://www.academia.edu/Documents/in/Molecular_Biology">Molecular Biology</a>, <script data-card-contents-for-ri="2513" type="text/json">{"id":2513,"name":"Molecular Biology","url":"https://www.academia.edu/Documents/in/Molecular_Biology?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="4987" href="https://www.academia.edu/Documents/in/Kinetics">Kinetics</a>, <script data-card-contents-for-ri="4987" type="text/json">{"id":4987,"name":"Kinetics","url":"https://www.academia.edu/Documents/in/Kinetics?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="51791" href="https://www.academia.edu/Documents/in/PCR">PCR</a><script data-card-contents-for-ri="51791" type="text/json">{"id":51791,"name":"PCR","url":"https://www.academia.edu/Documents/in/PCR?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=49670567]'), work: {"id":49670567,"title":"Detection of bcrabl fusion mRNA in samples of whole, unfractionated blood","created_at":"2021-07-09T14:56:46.613-07:00","url":"https://www.academia.edu/49670567/Detection_of_bcrabl_fusion_mRNA_in_samples_of_whole_unfractionated_blood?f_ri=14109","dom_id":"work_49670567","summary":null,"downloadable_attachments":[{"id":67957731,"asset_id":49670567,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":186741368,"first_name":"Kevin","last_name":"Cuddy","domain_name":"independent","page_name":"CuddyKevin","display_name":"Kevin Cuddy","profile_url":"https://independent.academia.edu/CuddyKevin?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":2513,"name":"Molecular Biology","url":"https://www.academia.edu/Documents/in/Molecular_Biology?f_ri=14109","nofollow":false},{"id":4987,"name":"Kinetics","url":"https://www.academia.edu/Documents/in/Kinetics?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":51791,"name":"PCR","url":"https://www.academia.edu/Documents/in/PCR?f_ri=14109","nofollow":false},{"id":118339,"name":"Polymerase Chain Reaction","url":"https://www.academia.edu/Documents/in/Polymerase_Chain_Reaction?f_ri=14109"},{"id":123472,"name":"Exploration","url":"https://www.academia.edu/Documents/in/Exploration?f_ri=14109"},{"id":150094,"name":"Fusion","url":"https://www.academia.edu/Documents/in/Fusion?f_ri=14109"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109"},{"id":372466,"name":"mRNA","url":"https://www.academia.edu/Documents/in/mRNA?f_ri=14109"},{"id":727150,"name":"Capture","url":"https://www.academia.edu/Documents/in/Capture?f_ri=14109"},{"id":862676,"name":"Affinity","url":"https://www.academia.edu/Documents/in/Affinity?f_ri=14109"},{"id":3189424,"name":"Blood Specimen Collection","url":"https://www.academia.edu/Documents/in/Blood_Specimen_Collection?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_12532764" data-work_id="12532764" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/12532764/Mechanisms_of_Uptake_and_Resistance_to_Troxacitabine_a_Novel_Deoxycytidine_Nucleoside_Analogue_In_Human_Leukemic_and_Solid_Tumor_Cell_Lines">Mechanisms of Uptake and Resistance to Troxacitabine, a Novel Deoxycytidine Nucleoside Analogue, In Human Leukemic and Solid Tumor Cell Lines</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Troxacitabine (Troxatyl; BCH-4556; (-)-2&#x27;-deoxy-3&#x27;-oxacytidine), a deoxycytidine analogue with an unusual dioxolane structure and nonnatural L-configuration, has potent antitumor activity in animal models and is in clinical... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_12532764" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Troxacitabine (Troxatyl; BCH-4556; (-)-2&#x27;-deoxy-3&#x27;-oxacytidine), a deoxycytidine analogue with an unusual dioxolane structure and nonnatural L-configuration, has potent antitumor activity in animal models and is in clinical trials against human malignancies. The current work ...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/12532764" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="193a5b54600c0a0d8d04fc373a9de48b" rel="nofollow" data-download="{"attachment_id":46109665,"asset_id":12532764,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46109665/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="31424522" href="https://independent.academia.edu/MackeyJohn">John Mackey</a><script data-card-contents-for-user="31424522" type="text/json">{"id":31424522,"first_name":"John","last_name":"Mackey","domain_name":"independent","page_name":"MackeyJohn","display_name":"John Mackey","profile_url":"https://independent.academia.edu/MackeyJohn?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_12532764 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="12532764"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 12532764, container: ".js-paper-rank-work_12532764", }); });</script></li><li class="js-percentile-work_12532764 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 12532764; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_12532764"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_12532764 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="12532764"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 12532764; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=12532764]").text(description); $(".js-view-count-work_12532764").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_12532764").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="12532764"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">17</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="4531" href="https://www.academia.edu/Documents/in/Clinical_Trial">Clinical Trial</a>, <script data-card-contents-for-ri="4531" type="text/json">{"id":4531,"name":"Clinical Trial","url":"https://www.academia.edu/Documents/in/Clinical_Trial?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="6021" href="https://www.academia.edu/Documents/in/Cancer">Cancer</a>, <script data-card-contents-for-ri="6021" type="text/json">{"id":6021,"name":"Cancer","url":"https://www.academia.edu/Documents/in/Cancer?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="11298" href="https://www.academia.edu/Documents/in/Membrane_Proteins">Membrane Proteins</a>, <script data-card-contents-for-ri="11298" type="text/json">{"id":11298,"name":"Membrane Proteins","url":"https://www.academia.edu/Documents/in/Membrane_Proteins?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="12980" href="https://www.academia.edu/Documents/in/Prostate_Cancer">Prostate Cancer</a><script data-card-contents-for-ri="12980" type="text/json">{"id":12980,"name":"Prostate Cancer","url":"https://www.academia.edu/Documents/in/Prostate_Cancer?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=12532764]'), work: {"id":12532764,"title":"Mechanisms of Uptake and Resistance to Troxacitabine, a Novel Deoxycytidine Nucleoside Analogue, In Human Leukemic and Solid Tumor Cell Lines","created_at":"2015-05-22T12:19:32.165-07:00","url":"https://www.academia.edu/12532764/Mechanisms_of_Uptake_and_Resistance_to_Troxacitabine_a_Novel_Deoxycytidine_Nucleoside_Analogue_In_Human_Leukemic_and_Solid_Tumor_Cell_Lines?f_ri=14109","dom_id":"work_12532764","summary":"Troxacitabine (Troxatyl; BCH-4556; (-)-2\u0026#x27;-deoxy-3\u0026#x27;-oxacytidine), a deoxycytidine analogue with an unusual dioxolane structure and nonnatural L-configuration, has potent antitumor activity in animal models and is in clinical trials against human malignancies. The current work ...","downloadable_attachments":[{"id":46109665,"asset_id":12532764,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":31424522,"first_name":"John","last_name":"Mackey","domain_name":"independent","page_name":"MackeyJohn","display_name":"John Mackey","profile_url":"https://independent.academia.edu/MackeyJohn?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":4531,"name":"Clinical Trial","url":"https://www.academia.edu/Documents/in/Clinical_Trial?f_ri=14109","nofollow":false},{"id":6021,"name":"Cancer","url":"https://www.academia.edu/Documents/in/Cancer?f_ri=14109","nofollow":false},{"id":11298,"name":"Membrane Proteins","url":"https://www.academia.edu/Documents/in/Membrane_Proteins?f_ri=14109","nofollow":false},{"id":12980,"name":"Prostate Cancer","url":"https://www.academia.edu/Documents/in/Prostate_Cancer?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109"},{"id":29082,"name":"Sequence Analysis","url":"https://www.academia.edu/Documents/in/Sequence_Analysis?f_ri=14109"},{"id":57808,"name":"Cell line","url":"https://www.academia.edu/Documents/in/Cell_line?f_ri=14109"},{"id":151951,"name":"Animal Model","url":"https://www.academia.edu/Documents/in/Animal_Model?f_ri=14109"},{"id":172083,"name":"Phosphorylation","url":"https://www.academia.edu/Documents/in/Phosphorylation?f_ri=14109"},{"id":386342,"name":"Sodium","url":"https://www.academia.edu/Documents/in/Sodium?f_ri=14109"},{"id":440014,"name":"Tritium","url":"https://www.academia.edu/Documents/in/Tritium?f_ri=14109"},{"id":585573,"name":"Amino Acid Profile","url":"https://www.academia.edu/Documents/in/Amino_Acid_Profile?f_ri=14109"},{"id":809881,"name":"Amino Acid Sequence","url":"https://www.academia.edu/Documents/in/Amino_Acid_Sequence?f_ri=14109"},{"id":920744,"name":"Antitumor Activity","url":"https://www.academia.edu/Documents/in/Antitumor_Activity?f_ri=14109"},{"id":967588,"name":"Resistance Genes Mechanism)","url":"https://www.academia.edu/Documents/in/Resistance_Genes_Mechanism_?f_ri=14109"},{"id":1212103,"name":"Antineoplastic Agents","url":"https://www.academia.edu/Documents/in/Antineoplastic_Agents?f_ri=14109"},{"id":2467566,"name":"Molecular Sequence Data","url":"https://www.academia.edu/Documents/in/Molecular_Sequence_Data?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_22923863" data-work_id="22923863" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/22923863/Proposals_for_standardized_protocols_for_cytogenetic_analyses_of_acute_leukemias_chronic_lymphocytic_leukemia_chronic_myeloid_leukemia_chronic_myeloproliferative_disorders_and_myelodysplastic_syndromes">Proposals for standardized protocols for cytogenetic analyses of acute leukemias, chronic lymphocytic leukemia, chronic myeloid leukemia, chronic myeloproliferative disorders, and myelodysplastic syndromes</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/22923863" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="fbbfe1152ee2c73f5e26b3f26c8c7d67" rel="nofollow" data-download="{"attachment_id":43457591,"asset_id":22923863,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/43457591/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="44615164" href="https://independent.academia.edu/JochenHarbott">Jochen Harbott</a><script data-card-contents-for-user="44615164" type="text/json">{"id":44615164,"first_name":"Jochen","last_name":"Harbott","domain_name":"independent","page_name":"JochenHarbott","display_name":"Jochen Harbott","profile_url":"https://independent.academia.edu/JochenHarbott?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_22923863 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="22923863"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 22923863, container: ".js-paper-rank-work_22923863", }); });</script></li><li class="js-percentile-work_22923863 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 22923863; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_22923863"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_22923863 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="22923863"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 22923863; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=22923863]").text(description); $(".js-view-count-work_22923863").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_22923863").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="22923863"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">7</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="59057" href="https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia">Acute Myeloid Leukemia</a>, <script data-card-contents-for-ri="59057" type="text/json">{"id":59057,"name":"Acute Myeloid Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="67422" href="https://www.academia.edu/Documents/in/Myelodysplastic_Syndrome">Myelodysplastic Syndrome</a>, <script data-card-contents-for-ri="67422" type="text/json">{"id":67422,"name":"Myelodysplastic Syndrome","url":"https://www.academia.edu/Documents/in/Myelodysplastic_Syndrome?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="82976" href="https://www.academia.edu/Documents/in/Chronic_Lymphocytic_Leukemia">Chronic Lymphocytic Leukemia</a><script data-card-contents-for-ri="82976" type="text/json">{"id":82976,"name":"Chronic Lymphocytic Leukemia","url":"https://www.academia.edu/Documents/in/Chronic_Lymphocytic_Leukemia?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=22923863]'), work: {"id":22923863,"title":"Proposals for standardized protocols for cytogenetic analyses of acute leukemias, chronic lymphocytic leukemia, chronic myeloid leukemia, chronic myeloproliferative disorders, and myelodysplastic syndromes","created_at":"2016-03-07T04:50:00.506-08:00","url":"https://www.academia.edu/22923863/Proposals_for_standardized_protocols_for_cytogenetic_analyses_of_acute_leukemias_chronic_lymphocytic_leukemia_chronic_myeloid_leukemia_chronic_myeloproliferative_disorders_and_myelodysplastic_syndromes?f_ri=14109","dom_id":"work_22923863","summary":null,"downloadable_attachments":[{"id":43457591,"asset_id":22923863,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":44615164,"first_name":"Jochen","last_name":"Harbott","domain_name":"independent","page_name":"JochenHarbott","display_name":"Jochen Harbott","profile_url":"https://independent.academia.edu/JochenHarbott?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":59057,"name":"Acute Myeloid Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia?f_ri=14109","nofollow":false},{"id":67422,"name":"Myelodysplastic Syndrome","url":"https://www.academia.edu/Documents/in/Myelodysplastic_Syndrome?f_ri=14109","nofollow":false},{"id":82976,"name":"Chronic Lymphocytic Leukemia","url":"https://www.academia.edu/Documents/in/Chronic_Lymphocytic_Leukemia?f_ri=14109","nofollow":false},{"id":153639,"name":"Karyotyping","url":"https://www.academia.edu/Documents/in/Karyotyping?f_ri=14109"},{"id":162159,"name":"Differential Diagnosis","url":"https://www.academia.edu/Documents/in/Differential_Diagnosis?f_ri=14109"},{"id":358328,"name":"Chronic myeloid leukemia","url":"https://www.academia.edu/Documents/in/Chronic_myeloid_leukemia?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_21214225" data-work_id="21214225" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/21214225/Pathway_activation_patterns_in_diffuse_large_B_cell_lymphomas">Pathway activation patterns in diffuse large B-cell lymphomas</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/21214225" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="b930799977909a2e0466dbc041125596" rel="nofollow" data-download="{"attachment_id":41765689,"asset_id":21214225,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/41765689/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="42361496" href="https://independent.academia.edu/HStein4">H. Stein</a><script data-card-contents-for-user="42361496" type="text/json">{"id":42361496,"first_name":"H.","last_name":"Stein","domain_name":"independent","page_name":"HStein4","display_name":"H. Stein","profile_url":"https://independent.academia.edu/HStein4?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_21214225 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="21214225"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 21214225, container: ".js-paper-rank-work_21214225", }); });</script></li><li class="js-percentile-work_21214225 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 21214225; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_21214225"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_21214225 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="21214225"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 21214225; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=21214225]").text(description); $(".js-view-count-work_21214225").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_21214225").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="21214225"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">16</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="156" href="https://www.academia.edu/Documents/in/Genetics">Genetics</a>, <script data-card-contents-for-ri="156" type="text/json">{"id":156,"name":"Genetics","url":"https://www.academia.edu/Documents/in/Genetics?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="4233" href="https://www.academia.edu/Documents/in/Computational_Biology">Computational Biology</a>, <script data-card-contents-for-ri="4233" type="text/json">{"id":4233,"name":"Computational Biology","url":"https://www.academia.edu/Documents/in/Computational_Biology?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="12071" href="https://www.academia.edu/Documents/in/Immunohistochemistry">Immunohistochemistry</a>, <script data-card-contents-for-ri="12071" type="text/json">{"id":12071,"name":"Immunohistochemistry","url":"https://www.academia.edu/Documents/in/Immunohistochemistry?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a><script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=21214225]'), work: {"id":21214225,"title":"Pathway activation patterns in diffuse large B-cell lymphomas","created_at":"2016-01-30T01:14:05.751-08:00","url":"https://www.academia.edu/21214225/Pathway_activation_patterns_in_diffuse_large_B_cell_lymphomas?f_ri=14109","dom_id":"work_21214225","summary":null,"downloadable_attachments":[{"id":41765689,"asset_id":21214225,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":42361496,"first_name":"H.","last_name":"Stein","domain_name":"independent","page_name":"HStein4","display_name":"H. Stein","profile_url":"https://independent.academia.edu/HStein4?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":156,"name":"Genetics","url":"https://www.academia.edu/Documents/in/Genetics?f_ri=14109","nofollow":false},{"id":4233,"name":"Computational Biology","url":"https://www.academia.edu/Documents/in/Computational_Biology?f_ri=14109","nofollow":false},{"id":12071,"name":"Immunohistochemistry","url":"https://www.academia.edu/Documents/in/Immunohistochemistry?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":17856,"name":"Cell Signaling","url":"https://www.academia.edu/Documents/in/Cell_Signaling?f_ri=14109"},{"id":27784,"name":"Gene expression","url":"https://www.academia.edu/Documents/in/Gene_expression?f_ri=14109"},{"id":38831,"name":"Signal Transduction","url":"https://www.academia.edu/Documents/in/Signal_Transduction?f_ri=14109"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109"},{"id":376494,"name":"Epithelium","url":"https://www.academia.edu/Documents/in/Epithelium?f_ri=14109"},{"id":410532,"name":"Clinical Data","url":"https://www.academia.edu/Documents/in/Clinical_Data?f_ri=14109"},{"id":541328,"name":"Diffuse Large B-Cell Lymphoma","url":"https://www.academia.edu/Documents/in/Diffuse_Large_B-Cell_Lymphoma?f_ri=14109"},{"id":887449,"name":"Supervised machine learning","url":"https://www.academia.edu/Documents/in/Supervised_machine_learning?f_ri=14109"},{"id":1157148,"name":"Cell Survival","url":"https://www.academia.edu/Documents/in/Cell_Survival?f_ri=14109"},{"id":1810445,"name":"Gene expression profiling","url":"https://www.academia.edu/Documents/in/Gene_expression_profiling?f_ri=14109"},{"id":1954130,"name":"Cell Growth","url":"https://www.academia.edu/Documents/in/Cell_Growth?f_ri=14109"},{"id":2079216,"name":"Lymph nodes","url":"https://www.academia.edu/Documents/in/Lymph_nodes?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_18607469 coauthored" data-work_id="18607469" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/18607469/Prospective_evaluation_of_oral_mucositis_in_acute_leukemia_patients_receiving_chemotherapy">Prospective evaluation of oral mucositis in acute leukemia patients receiving chemotherapy</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/18607469" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="53a0a11f47f3450a7047b9dd8f8a90be" rel="nofollow" data-download="{"attachment_id":42317330,"asset_id":18607469,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42317330/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="38790157" href="https://uam-xochimilco.academia.edu/GAnayasaavedra">G. Anaya-Saavedra</a><script data-card-contents-for-user="38790157" type="text/json">{"id":38790157,"first_name":"G.","last_name":"Anaya-Saavedra","domain_name":"uam-xochimilco","page_name":"GAnayasaavedra","display_name":"G. Anaya-Saavedra","profile_url":"https://uam-xochimilco.academia.edu/GAnayasaavedra?f_ri=14109","photo":"https://0.academia-photos.com/38790157/15638059/17434656/s65_g..anaya-saavedra.jpg"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-18607469">+1</span><div class="hidden js-additional-users-18607469"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/VeliaRam%C3%ADrezamador">Velia Ramírez-amador</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-18607469'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-18607469').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_18607469 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="18607469"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 18607469, container: ".js-paper-rank-work_18607469", }); });</script></li><li class="js-percentile-work_18607469 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 18607469; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_18607469"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_18607469 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="18607469"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 18607469; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=18607469]").text(description); $(".js-view-count-work_18607469").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_18607469").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="18607469"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">16</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="59057" href="https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia">Acute Myeloid Leukemia</a>, <script data-card-contents-for-ri="59057" type="text/json">{"id":59057,"name":"Acute Myeloid Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a><script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=18607469]'), work: {"id":18607469,"title":"Prospective evaluation of oral mucositis in acute leukemia patients receiving chemotherapy","created_at":"2015-11-18T13:34:39.837-08:00","url":"https://www.academia.edu/18607469/Prospective_evaluation_of_oral_mucositis_in_acute_leukemia_patients_receiving_chemotherapy?f_ri=14109","dom_id":"work_18607469","summary":null,"downloadable_attachments":[{"id":42317330,"asset_id":18607469,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":38790157,"first_name":"G.","last_name":"Anaya-Saavedra","domain_name":"uam-xochimilco","page_name":"GAnayasaavedra","display_name":"G. Anaya-Saavedra","profile_url":"https://uam-xochimilco.academia.edu/GAnayasaavedra?f_ri=14109","photo":"https://0.academia-photos.com/38790157/15638059/17434656/s65_g..anaya-saavedra.jpg"},{"id":38650453,"first_name":"Velia","last_name":"Ramírez-amador","domain_name":"independent","page_name":"VeliaRamírezamador","display_name":"Velia Ramírez-amador","profile_url":"https://independent.academia.edu/VeliaRam%C3%ADrezamador?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false},{"id":59057,"name":"Acute Myeloid Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia?f_ri=14109","nofollow":false},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=14109","nofollow":false},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=14109"},{"id":144361,"name":"Supportive Care","url":"https://www.academia.edu/Documents/in/Supportive_Care?f_ri=14109"},{"id":168477,"name":"Flow measurement","url":"https://www.academia.edu/Documents/in/Flow_measurement?f_ri=14109"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=14109"},{"id":241044,"name":"Food intake","url":"https://www.academia.edu/Documents/in/Food_intake?f_ri=14109"},{"id":330953,"name":"Longitudinal Studies","url":"https://www.academia.edu/Documents/in/Longitudinal_Studies?f_ri=14109"},{"id":371390,"name":"Stomatitis","url":"https://www.academia.edu/Documents/in/Stomatitis?f_ri=14109"},{"id":414843,"name":"Longitudinal Study","url":"https://www.academia.edu/Documents/in/Longitudinal_Study?f_ri=14109"},{"id":550226,"name":"Oral mucositis","url":"https://www.academia.edu/Documents/in/Oral_mucositis?f_ri=14109"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=14109"},{"id":698785,"name":"Side Effect","url":"https://www.academia.edu/Documents/in/Side_Effect?f_ri=14109"},{"id":1212103,"name":"Antineoplastic Agents","url":"https://www.academia.edu/Documents/in/Antineoplastic_Agents?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_80615884" data-work_id="80615884" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/80615884/Treatment_of_patients_with_myelodysplastic_syndrome_with_amifostine">Treatment of patients with myelodysplastic syndrome with amifostine</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/80615884" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="4a331e1c62490d2f6da9a1960eec73ec" rel="nofollow" data-download="{"attachment_id":86938877,"asset_id":80615884,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/86938877/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="44285471" href="https://independent.academia.edu/TheodorosMarinakis">Theodoros Marinakis</a><script data-card-contents-for-user="44285471" type="text/json">{"id":44285471,"first_name":"Theodoros","last_name":"Marinakis","domain_name":"independent","page_name":"TheodorosMarinakis","display_name":"Theodoros Marinakis","profile_url":"https://independent.academia.edu/TheodorosMarinakis?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_80615884 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="80615884"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 80615884, container: ".js-paper-rank-work_80615884", }); });</script></li><li class="js-percentile-work_80615884 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 80615884; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_80615884"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_80615884 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="80615884"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 80615884; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=80615884]").text(description); $(".js-view-count-work_80615884").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_80615884").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="80615884"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">13</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="38650" href="https://www.academia.edu/Documents/in/Cell_Division">Cell Division</a>, <script data-card-contents-for-ri="38650" type="text/json">{"id":38650,"name":"Cell Division","url":"https://www.academia.edu/Documents/in/Cell_Division?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="53113" href="https://www.academia.edu/Documents/in/Hematopoietic_Stem_Cells">Hematopoietic Stem Cells</a>, <script data-card-contents-for-ri="53113" type="text/json">{"id":53113,"name":"Hematopoietic Stem Cells","url":"https://www.academia.edu/Documents/in/Hematopoietic_Stem_Cells?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="59057" href="https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia">Acute Myeloid Leukemia</a><script data-card-contents-for-ri="59057" type="text/json">{"id":59057,"name":"Acute Myeloid Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=80615884]'), work: {"id":80615884,"title":"Treatment of patients with myelodysplastic syndrome with amifostine","created_at":"2022-06-03T07:10:26.950-07:00","url":"https://www.academia.edu/80615884/Treatment_of_patients_with_myelodysplastic_syndrome_with_amifostine?f_ri=14109","dom_id":"work_80615884","summary":null,"downloadable_attachments":[{"id":86938877,"asset_id":80615884,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":44285471,"first_name":"Theodoros","last_name":"Marinakis","domain_name":"independent","page_name":"TheodorosMarinakis","display_name":"Theodoros Marinakis","profile_url":"https://independent.academia.edu/TheodorosMarinakis?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":38650,"name":"Cell Division","url":"https://www.academia.edu/Documents/in/Cell_Division?f_ri=14109","nofollow":false},{"id":53113,"name":"Hematopoietic Stem Cells","url":"https://www.academia.edu/Documents/in/Hematopoietic_Stem_Cells?f_ri=14109","nofollow":false},{"id":59057,"name":"Acute Myeloid Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia?f_ri=14109","nofollow":false},{"id":67422,"name":"Myelodysplastic Syndrome","url":"https://www.academia.edu/Documents/in/Myelodysplastic_Syndrome?f_ri=14109"},{"id":159239,"name":"Bone marrow","url":"https://www.academia.edu/Documents/in/Bone_marrow?f_ri=14109"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=14109"},{"id":698785,"name":"Side Effect","url":"https://www.academia.edu/Documents/in/Side_Effect?f_ri=14109"},{"id":2236523,"name":"amifostine","url":"https://www.academia.edu/Documents/in/amifostine?f_ri=14109"},{"id":3360152,"name":"Absolute Neutrophil Count","url":"https://www.academia.edu/Documents/in/Absolute_Neutrophil_Count?f_ri=14109"},{"id":3541888,"name":"Myelodysplastic syndromes","url":"https://www.academia.edu/Documents/in/Myelodysplastic_syndromes?f_ri=14109"},{"id":3635999,"name":"Complete Blood Count","url":"https://www.academia.edu/Documents/in/Complete_Blood_Count-1?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_75037278" data-work_id="75037278" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/75037278/Recurrent_somatic_mutations_are_rare_in_patients_with_cryptic_dyskeratosis_congenita">Recurrent somatic mutations are rare in patients with cryptic dyskeratosis congenita</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Dyskeratosis congenita (DKC) is a paradigmatic telomere disorder characterized by substantial and premature telomere shortening, bone marrow failure, and a dramatically increased risk of developing myelodysplastic syndrome (MDS) or acute... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_75037278" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Dyskeratosis congenita (DKC) is a paradigmatic telomere disorder characterized by substantial and premature telomere shortening, bone marrow failure, and a dramatically increased risk of developing myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). DKC can occur as a late-onset, so-called cryptic form, with first manifestation in adults. Somatic MDS-related mutations are found in up to 35% of patients with acquired aplastic anemia (AA), especially in patients with short telomeres. The aim of our study was to investigate whether cryptic DKC is associated with an increased incidence of MDS-related somatic mutations, thereby linking the accelerated telomere shortening with the increased risk of MDS/AML. Samples from 15 adult patients (median age: 42 years, range: 23-60 years) with molecularly confirmed cryptic DKC were screened using next-generation gene panel sequencing to detect MDS-related somatic variants. Only one of the 15 patients (7%) demonstrated a clinically rele...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/75037278" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="05124e980c2e458e8bb5bfb9ddae8df3" rel="nofollow" data-download="{"attachment_id":82969391,"asset_id":75037278,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/82969391/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="61709426" href="https://independent.academia.edu/SelimCorbacioglu">Selim Corbacioglu</a><script data-card-contents-for-user="61709426" type="text/json">{"id":61709426,"first_name":"Selim","last_name":"Corbacioglu","domain_name":"independent","page_name":"SelimCorbacioglu","display_name":"Selim Corbacioglu","profile_url":"https://independent.academia.edu/SelimCorbacioglu?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_75037278 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="75037278"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 75037278, container: ".js-paper-rank-work_75037278", }); });</script></li><li class="js-percentile-work_75037278 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 75037278; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_75037278"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_75037278 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="75037278"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 75037278; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=75037278]").text(description); $(".js-view-count-work_75037278").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_75037278").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="75037278"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">3</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a><script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=75037278]'), work: {"id":75037278,"title":"Recurrent somatic mutations are rare in patients with cryptic dyskeratosis congenita","created_at":"2022-03-31T00:13:11.013-07:00","url":"https://www.academia.edu/75037278/Recurrent_somatic_mutations_are_rare_in_patients_with_cryptic_dyskeratosis_congenita?f_ri=14109","dom_id":"work_75037278","summary":"Dyskeratosis congenita (DKC) is a paradigmatic telomere disorder characterized by substantial and premature telomere shortening, bone marrow failure, and a dramatically increased risk of developing myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). DKC can occur as a late-onset, so-called cryptic form, with first manifestation in adults. Somatic MDS-related mutations are found in up to 35% of patients with acquired aplastic anemia (AA), especially in patients with short telomeres. The aim of our study was to investigate whether cryptic DKC is associated with an increased incidence of MDS-related somatic mutations, thereby linking the accelerated telomere shortening with the increased risk of MDS/AML. Samples from 15 adult patients (median age: 42 years, range: 23-60 years) with molecularly confirmed cryptic DKC were screened using next-generation gene panel sequencing to detect MDS-related somatic variants. Only one of the 15 patients (7%) demonstrated a clinically rele...","downloadable_attachments":[{"id":82969391,"asset_id":75037278,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":61709426,"first_name":"Selim","last_name":"Corbacioglu","domain_name":"independent","page_name":"SelimCorbacioglu","display_name":"Selim Corbacioglu","profile_url":"https://independent.academia.edu/SelimCorbacioglu?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=14109","nofollow":false},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_51547869" data-work_id="51547869" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/51547869/Optimizing_autologous_nonmobilized_mononuclear_cell_collections_for_cellular_therapy_in_pediatric_patients_with_high_risk_leukemia">Optimizing autologous nonmobilized mononuclear cell collections for cellular therapy in pediatric patients with high-risk leukemia</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The manufacturing of cellular products for immunotherapy, such as chimeric antigen receptor T cells, requires successful collection of mononuclear cells. Collections from children with high-risk leukemia present a challenge, especially... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_51547869" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The manufacturing of cellular products for immunotherapy, such as chimeric antigen receptor T cells, requires successful collection of mononuclear cells. Collections from children with high-risk leukemia present a challenge, especially because the established COBE Spectra apheresis device is being replaced by the novel Spectra Optia device (Optia) in many institutions. Published experience for mononuclear cell collections in children with Optia is lacking. Our aim was to compare the two collection devices and describe modified settings on the Optia to optimize mononuclear cell collections. As a quality initiative, we retrospectively collected and compared data from mononuclear cell collections on both devices. Collected data included patient&#39;s clinical characteristics; collection parameters, including precollection lymphocyte/CD3 counts, total blood volumes processed, runtimes, and side effects (including complete blood count and electrolyte changes); and product characteristics...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/51547869" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="5bb508c71dbc81483ac44ad4215e6b2e" rel="nofollow" data-download="{"attachment_id":69226471,"asset_id":51547869,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/69226471/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="197212742" href="https://independent.academia.edu/DiMolaMaria">Maria Di Mola</a><script data-card-contents-for-user="197212742" type="text/json">{"id":197212742,"first_name":"Maria","last_name":"Di Mola","domain_name":"independent","page_name":"DiMolaMaria","display_name":"Maria Di Mola","profile_url":"https://independent.academia.edu/DiMolaMaria?f_ri=14109","photo":"https://0.academia-photos.com/197212742/59346814/47590493/s65_maria.di_mola.jpeg"}</script></span></span></li><li class="js-paper-rank-work_51547869 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="51547869"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 51547869, container: ".js-paper-rank-work_51547869", }); });</script></li><li class="js-percentile-work_51547869 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 51547869; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_51547869"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_51547869 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="51547869"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 51547869; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=51547869]").text(description); $(".js-view-count-work_51547869").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_51547869").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="51547869"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">11</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="1290" href="https://www.academia.edu/Documents/in/Immunology">Immunology</a>, <script data-card-contents-for-ri="1290" type="text/json">{"id":1290,"name":"Immunology","url":"https://www.academia.edu/Documents/in/Immunology?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="64933" href="https://www.academia.edu/Documents/in/Child">Child</a><script data-card-contents-for-ri="64933" type="text/json">{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=51547869]'), work: {"id":51547869,"title":"Optimizing autologous nonmobilized mononuclear cell collections for cellular therapy in pediatric patients with high-risk leukemia","created_at":"2021-09-08T21:23:34.811-07:00","url":"https://www.academia.edu/51547869/Optimizing_autologous_nonmobilized_mononuclear_cell_collections_for_cellular_therapy_in_pediatric_patients_with_high_risk_leukemia?f_ri=14109","dom_id":"work_51547869","summary":"The manufacturing of cellular products for immunotherapy, such as chimeric antigen receptor T cells, requires successful collection of mononuclear cells. Collections from children with high-risk leukemia present a challenge, especially because the established COBE Spectra apheresis device is being replaced by the novel Spectra Optia device (Optia) in many institutions. Published experience for mononuclear cell collections in children with Optia is lacking. Our aim was to compare the two collection devices and describe modified settings on the Optia to optimize mononuclear cell collections. As a quality initiative, we retrospectively collected and compared data from mononuclear cell collections on both devices. Collected data included patient\u0026#39;s clinical characteristics; collection parameters, including precollection lymphocyte/CD3 counts, total blood volumes processed, runtimes, and side effects (including complete blood count and electrolyte changes); and product characteristics...","downloadable_attachments":[{"id":69226471,"asset_id":51547869,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":197212742,"first_name":"Maria","last_name":"Di Mola","domain_name":"independent","page_name":"DiMolaMaria","display_name":"Maria Di Mola","profile_url":"https://independent.academia.edu/DiMolaMaria?f_ri=14109","photo":"https://0.academia-photos.com/197212742/59346814/47590493/s65_maria.di_mola.jpeg"}],"research_interests":[{"id":1290,"name":"Immunology","url":"https://www.academia.edu/Documents/in/Immunology?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=14109","nofollow":false},{"id":126863,"name":"Immunotherapy","url":"https://www.academia.edu/Documents/in/Immunotherapy?f_ri=14109"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=14109"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=14109"},{"id":1307860,"name":"Transfusion","url":"https://www.academia.edu/Documents/in/Transfusion?f_ri=14109"},{"id":2489700,"name":"Child preschool","url":"https://www.academia.edu/Documents/in/Child_preschool?f_ri=14109"},{"id":3789879,"name":"Cardiovascular medicine and haematology","url":"https://www.academia.edu/Documents/in/Cardiovascular_medicine_and_haematology?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_4203841" data-work_id="4203841" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/4203841/A_10_year_experience_of_infection_following_carotid_endarterectomy_with_patch_angioplasty">A 10-year experience of infection following carotid endarterectomy with patch angioplasty</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/4203841" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="2370804f4d139a80e4d06dcf36c9cbdd" rel="nofollow" data-download="{"attachment_id":49987415,"asset_id":4203841,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/49987415/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="5086891" href="https://auckland.academia.edu/DanielDear">Daniel Dear</a><script data-card-contents-for-user="5086891" type="text/json">{"id":5086891,"first_name":"Daniel","last_name":"Dear","domain_name":"auckland","page_name":"DanielDear","display_name":"Daniel Dear","profile_url":"https://auckland.academia.edu/DanielDear?f_ri=14109","photo":"https://0.academia-photos.com/5086891/2222686/2601909/s65_daniel.dear.jpg"}</script></span></span></li><li class="js-paper-rank-work_4203841 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="4203841"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 4203841, container: ".js-paper-rank-work_4203841", }); });</script></li><li class="js-percentile-work_4203841 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 4203841; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_4203841"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_4203841 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="4203841"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 4203841; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=4203841]").text(description); $(".js-view-count-work_4203841").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_4203841").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="4203841"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">15</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="647" href="https://www.academia.edu/Documents/in/Surgery">Surgery</a>, <script data-card-contents-for-ri="647" type="text/json">{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="12426" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a>, <script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="25398" href="https://www.academia.edu/Documents/in/Vascular_Surgery">Vascular Surgery</a><script data-card-contents-for-ri="25398" type="text/json">{"id":25398,"name":"Vascular Surgery","url":"https://www.academia.edu/Documents/in/Vascular_Surgery?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=4203841]'), work: {"id":4203841,"title":"A 10-year experience of infection following carotid endarterectomy with patch angioplasty","created_at":"2013-08-09T01:40:51.306-07:00","url":"https://www.academia.edu/4203841/A_10_year_experience_of_infection_following_carotid_endarterectomy_with_patch_angioplasty?f_ri=14109","dom_id":"work_4203841","summary":null,"downloadable_attachments":[{"id":49987415,"asset_id":4203841,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":5086891,"first_name":"Daniel","last_name":"Dear","domain_name":"auckland","page_name":"DanielDear","display_name":"Daniel Dear","profile_url":"https://auckland.academia.edu/DanielDear?f_ri=14109","photo":"https://0.academia-photos.com/5086891/2222686/2601909/s65_daniel.dear.jpg"}],"research_interests":[{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery?f_ri=14109","nofollow":false},{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":25398,"name":"Vascular Surgery","url":"https://www.academia.edu/Documents/in/Vascular_Surgery?f_ri=14109","nofollow":false},{"id":228722,"name":"Vascular","url":"https://www.academia.edu/Documents/in/Vascular?f_ri=14109"},{"id":247700,"name":"Angioplasty","url":"https://www.academia.edu/Documents/in/Angioplasty?f_ri=14109"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=14109"},{"id":335984,"name":"Anti-Bacterial Agents","url":"https://www.academia.edu/Documents/in/Anti-Bacterial_Agents?f_ri=14109"},{"id":424621,"name":"Drainage","url":"https://www.academia.edu/Documents/in/Drainage?f_ri=14109"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=14109"},{"id":480301,"name":"Carotid Endarterectomy","url":"https://www.academia.edu/Documents/in/Carotid_Endarterectomy?f_ri=14109"},{"id":788697,"name":"SAPHENOUS VEIN","url":"https://www.academia.edu/Documents/in/SAPHENOUS_VEIN?f_ri=14109"},{"id":911984,"name":"Polytetrafluoroethylene","url":"https://www.academia.edu/Documents/in/Polytetrafluoroethylene?f_ri=14109"},{"id":1031067,"name":"Biocompatible Materials","url":"https://www.academia.edu/Documents/in/Biocompatible_Materials?f_ri=14109"},{"id":1700489,"name":"Carotid Stenosis","url":"https://www.academia.edu/Documents/in/Carotid_Stenosis?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_7495830" data-work_id="7495830" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/7495830/Incidence_and_prognostic_relevance_of_CD34_expression_in_acute_myeloblastic_leukemia_Analysis_of_141_cases">Incidence and prognostic relevance of CD34 expression in acute myeloblastic leukemia: Analysis of 141 cases</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/7495830" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="fdfac64b5cbee0dadbaa7d41c4fd8604" rel="nofollow" data-download="{"attachment_id":48450322,"asset_id":7495830,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48450322/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="13388626" href="https://independent.academia.edu/antoniodevivo">antonio de vivo</a><script data-card-contents-for-user="13388626" type="text/json">{"id":13388626,"first_name":"antonio","last_name":"de vivo","domain_name":"independent","page_name":"antoniodevivo","display_name":"antonio de vivo","profile_url":"https://independent.academia.edu/antoniodevivo?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_7495830 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="7495830"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 7495830, container: ".js-paper-rank-work_7495830", }); });</script></li><li class="js-percentile-work_7495830 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 7495830; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_7495830"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_7495830 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="7495830"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 7495830; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=7495830]").text(description); $(".js-view-count-work_7495830").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_7495830").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="7495830"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">12</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="6599" href="https://www.academia.edu/Documents/in/Flow_Cytometry">Flow Cytometry</a>, <script data-card-contents-for-ri="6599" type="text/json">{"id":6599,"name":"Flow Cytometry","url":"https://www.academia.edu/Documents/in/Flow_Cytometry?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="59057" href="https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia">Acute Myeloid Leukemia</a><script data-card-contents-for-ri="59057" type="text/json">{"id":59057,"name":"Acute Myeloid Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=7495830]'), work: {"id":7495830,"title":"Incidence and prognostic relevance of CD34 expression in acute myeloblastic leukemia: Analysis of 141 cases","created_at":"2014-06-29T06:17:57.719-07:00","url":"https://www.academia.edu/7495830/Incidence_and_prognostic_relevance_of_CD34_expression_in_acute_myeloblastic_leukemia_Analysis_of_141_cases?f_ri=14109","dom_id":"work_7495830","summary":null,"downloadable_attachments":[{"id":48450322,"asset_id":7495830,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":13388626,"first_name":"antonio","last_name":"de vivo","domain_name":"independent","page_name":"antoniodevivo","display_name":"antonio de vivo","profile_url":"https://independent.academia.edu/antoniodevivo?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":6599,"name":"Flow Cytometry","url":"https://www.academia.edu/Documents/in/Flow_Cytometry?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false},{"id":59057,"name":"Acute Myeloid Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia?f_ri=14109","nofollow":false},{"id":147196,"name":"Monoclonal Antibodies","url":"https://www.academia.edu/Documents/in/Monoclonal_Antibodies?f_ri=14109"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=14109"},{"id":489727,"name":"Prognosis","url":"https://www.academia.edu/Documents/in/Prognosis?f_ri=14109"},{"id":571886,"name":"Immunophenotyping","url":"https://www.academia.edu/Documents/in/Immunophenotyping?f_ri=14109"},{"id":749302,"name":"Indexation","url":"https://www.academia.edu/Documents/in/Indexation?f_ri=14109"},{"id":766014,"name":"Monoclonal Antibody","url":"https://www.academia.edu/Documents/in/Monoclonal_Antibody?f_ri=14109"},{"id":1225372,"name":"Overall Survival","url":"https://www.academia.edu/Documents/in/Overall_Survival?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_8186818" data-work_id="8186818" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/8186818/Induction_of_apoptosis_by_streptochlorin_isolated_from_Streptomyces_sp_in_human_leukemic_U937_cells">Induction of apoptosis by streptochlorin isolated from Streptomyces sp. in human leukemic U937 cells</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/8186818" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="154671d1ffa3b868064dbcd7c94bb4b9" rel="nofollow" data-download="{"attachment_id":48189668,"asset_id":8186818,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48189668/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="16029363" href="https://independent.academia.edu/HeeJaeshin">Hee Jae shin</a><script data-card-contents-for-user="16029363" type="text/json">{"id":16029363,"first_name":"Hee Jae","last_name":"shin","domain_name":"independent","page_name":"HeeJaeshin","display_name":"Hee Jae shin","profile_url":"https://independent.academia.edu/HeeJaeshin?f_ri=14109","photo":"https://0.academia-photos.com/16029363/86383640/75047510/s65_hee_jae.shin.png"}</script></span></span></li><li class="js-paper-rank-work_8186818 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="8186818"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 8186818, container: ".js-paper-rank-work_8186818", }); });</script></li><li class="js-percentile-work_8186818 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 8186818; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_8186818"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_8186818 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="8186818"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 8186818; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=8186818]").text(description); $(".js-view-count-work_8186818").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_8186818").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="8186818"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">21</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="24731" href="https://www.academia.edu/Documents/in/Apoptosis">Apoptosis</a>, <script data-card-contents-for-ri="24731" type="text/json">{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="50841" href="https://www.academia.edu/Documents/in/Caspases">Caspases</a>, <script data-card-contents-for-ri="50841" type="text/json">{"id":50841,"name":"Caspases","url":"https://www.academia.edu/Documents/in/Caspases?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="51791" href="https://www.academia.edu/Documents/in/PCR">PCR</a><script data-card-contents-for-ri="51791" type="text/json">{"id":51791,"name":"PCR","url":"https://www.academia.edu/Documents/in/PCR?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=8186818]'), work: {"id":8186818,"title":"Induction of apoptosis by streptochlorin isolated from Streptomyces sp. in human leukemic U937 cells","created_at":"2014-09-03T12:01:02.477-07:00","url":"https://www.academia.edu/8186818/Induction_of_apoptosis_by_streptochlorin_isolated_from_Streptomyces_sp_in_human_leukemic_U937_cells?f_ri=14109","dom_id":"work_8186818","summary":null,"downloadable_attachments":[{"id":48189668,"asset_id":8186818,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":16029363,"first_name":"Hee Jae","last_name":"shin","domain_name":"independent","page_name":"HeeJaeshin","display_name":"Hee Jae shin","profile_url":"https://independent.academia.edu/HeeJaeshin?f_ri=14109","photo":"https://0.academia-photos.com/16029363/86383640/75047510/s65_hee_jae.shin.png"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis?f_ri=14109","nofollow":false},{"id":50841,"name":"Caspases","url":"https://www.academia.edu/Documents/in/Caspases?f_ri=14109","nofollow":false},{"id":51791,"name":"PCR","url":"https://www.academia.edu/Documents/in/PCR?f_ri=14109","nofollow":false},{"id":55172,"name":"Streptomyces","url":"https://www.academia.edu/Documents/in/Streptomyces?f_ri=14109"},{"id":63426,"name":"PLC","url":"https://www.academia.edu/Documents/in/PLC?f_ri=14109"},{"id":160498,"name":"TNF","url":"https://www.academia.edu/Documents/in/TNF?f_ri=14109"},{"id":168639,"name":"Bcl","url":"https://www.academia.edu/Documents/in/Bcl?f_ri=14109"},{"id":219007,"name":"Pi","url":"https://www.academia.edu/Documents/in/Pi?f_ri=14109"},{"id":247477,"name":"Caspase","url":"https://www.academia.edu/Documents/in/Caspase?f_ri=14109"},{"id":394477,"name":"Time Dependent","url":"https://www.academia.edu/Documents/in/Time_Dependent?f_ri=14109"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=14109"},{"id":467234,"name":"PBS","url":"https://www.academia.edu/Documents/in/PBS?f_ri=14109"},{"id":468416,"name":"Ecl","url":"https://www.academia.edu/Documents/in/Ecl?f_ri=14109"},{"id":518679,"name":"In Vitro Toxicology","url":"https://www.academia.edu/Documents/in/In_Vitro_Toxicology?f_ri=14109"},{"id":527895,"name":"MMP","url":"https://www.academia.edu/Documents/in/MMP?f_ri=14109"},{"id":769359,"name":"Growth Inhibition","url":"https://www.academia.edu/Documents/in/Growth_Inhibition?f_ri=14109"},{"id":1148360,"name":"Mitochondrial Membrane Potential","url":"https://www.academia.edu/Documents/in/Mitochondrial_Membrane_Potential?f_ri=14109"},{"id":1486366,"name":"PARP","url":"https://www.academia.edu/Documents/in/PARP?f_ri=14109"},{"id":1763968,"name":"Gene Expression Regulation","url":"https://www.academia.edu/Documents/in/Gene_Expression_Regulation?f_ri=14109"},{"id":2225479,"name":"Phospholipase C","url":"https://www.academia.edu/Documents/in/Phospholipase_C?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_11656002" data-work_id="11656002" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/11656002/The_role_of_T_cells_in_the_pathogenesis_of_myelodysplastic_syndromes_Passengers_and_drivers">The role of T-cells in the pathogenesis of myelodysplastic syndromes: Passengers and drivers</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/11656002" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="616d2b1e1450d2273e4b85f2a3e5d5a4" rel="nofollow" data-download="{"attachment_id":46586740,"asset_id":11656002,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46586740/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="28487184" href="https://uniss.academia.edu/ClaudioFozza">Claudio Fozza</a><script data-card-contents-for-user="28487184" type="text/json">{"id":28487184,"first_name":"Claudio","last_name":"Fozza","domain_name":"uniss","page_name":"ClaudioFozza","display_name":"Claudio Fozza","profile_url":"https://uniss.academia.edu/ClaudioFozza?f_ri=14109","photo":"https://gravatar.com/avatar/0932b1f5948008ffc0b22b91f2a9ceff?s=65"}</script></span></span></li><li class="js-paper-rank-work_11656002 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="11656002"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 11656002, container: ".js-paper-rank-work_11656002", }); });</script></li><li class="js-percentile-work_11656002 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 11656002; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_11656002"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_11656002 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="11656002"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 11656002; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=11656002]").text(description); $(".js-view-count-work_11656002").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_11656002").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="11656002"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">3</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a>, <script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="280237" href="https://www.academia.edu/Documents/in/T_lymphocytes">T lymphocytes</a><script data-card-contents-for-ri="280237" type="text/json">{"id":280237,"name":"T lymphocytes","url":"https://www.academia.edu/Documents/in/T_lymphocytes?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=11656002]'), work: {"id":11656002,"title":"The role of T-cells in the pathogenesis of myelodysplastic syndromes: Passengers and drivers","created_at":"2015-03-25T09:45:27.087-07:00","url":"https://www.academia.edu/11656002/The_role_of_T_cells_in_the_pathogenesis_of_myelodysplastic_syndromes_Passengers_and_drivers?f_ri=14109","dom_id":"work_11656002","summary":null,"downloadable_attachments":[{"id":46586740,"asset_id":11656002,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":28487184,"first_name":"Claudio","last_name":"Fozza","domain_name":"uniss","page_name":"ClaudioFozza","display_name":"Claudio Fozza","profile_url":"https://uniss.academia.edu/ClaudioFozza?f_ri=14109","photo":"https://gravatar.com/avatar/0932b1f5948008ffc0b22b91f2a9ceff?s=65"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109","nofollow":false},{"id":280237,"name":"T lymphocytes","url":"https://www.academia.edu/Documents/in/T_lymphocytes?f_ri=14109","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_20255765" data-work_id="20255765" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/20255765/SL_Kh_strain_of_mice_A_model_of_spontaneous_pre_B_lymphomas">SL/Kh strain of mice: A model of spontaneous pre-B-lymphomas</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/20255765" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="13e7a62c185b508eff55a9a79dbf0102" rel="nofollow" data-download="{"attachment_id":41972912,"asset_id":20255765,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/41972912/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="41467516" href="https://kyoto-u.academia.edu/HiroshiHiai">Hiroshi Hiai</a><script data-card-contents-for-user="41467516" type="text/json">{"id":41467516,"first_name":"Hiroshi","last_name":"Hiai","domain_name":"kyoto-u","page_name":"HiroshiHiai","display_name":"Hiroshi Hiai","profile_url":"https://kyoto-u.academia.edu/HiroshiHiai?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_20255765 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="20255765"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 20255765, container: ".js-paper-rank-work_20255765", }); });</script></li><li class="js-percentile-work_20255765 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 20255765; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_20255765"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_20255765 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="20255765"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 20255765; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=20255765]").text(description); $(".js-view-count-work_20255765").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_20255765").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="20255765"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">10</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="27784" href="https://www.academia.edu/Documents/in/Gene_expression">Gene expression</a>, <script data-card-contents-for-ri="27784" type="text/json">{"id":27784,"name":"Gene expression","url":"https://www.academia.edu/Documents/in/Gene_expression?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="60436" href="https://www.academia.edu/Documents/in/Cell_Differentiation">Cell Differentiation</a>, <script data-card-contents-for-ri="60436" type="text/json">{"id":60436,"name":"Cell Differentiation","url":"https://www.academia.edu/Documents/in/Cell_Differentiation?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="84760" href="https://www.academia.edu/Documents/in/Mice">Mice</a><script data-card-contents-for-ri="84760" type="text/json">{"id":84760,"name":"Mice","url":"https://www.academia.edu/Documents/in/Mice?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=20255765]'), work: {"id":20255765,"title":"SL/Kh strain of mice: A model of spontaneous pre-B-lymphomas","created_at":"2016-01-14T04:25:21.517-08:00","url":"https://www.academia.edu/20255765/SL_Kh_strain_of_mice_A_model_of_spontaneous_pre_B_lymphomas?f_ri=14109","dom_id":"work_20255765","summary":null,"downloadable_attachments":[{"id":41972912,"asset_id":20255765,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":41467516,"first_name":"Hiroshi","last_name":"Hiai","domain_name":"kyoto-u","page_name":"HiroshiHiai","display_name":"Hiroshi Hiai","profile_url":"https://kyoto-u.academia.edu/HiroshiHiai?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":27784,"name":"Gene expression","url":"https://www.academia.edu/Documents/in/Gene_expression?f_ri=14109","nofollow":false},{"id":60436,"name":"Cell Differentiation","url":"https://www.academia.edu/Documents/in/Cell_Differentiation?f_ri=14109","nofollow":false},{"id":84760,"name":"Mice","url":"https://www.academia.edu/Documents/in/Mice?f_ri=14109","nofollow":false},{"id":181569,"name":"Proteins","url":"https://www.academia.edu/Documents/in/Proteins?f_ri=14109"},{"id":213897,"name":"Phenotype","url":"https://www.academia.edu/Documents/in/Phenotype?f_ri=14109"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109"},{"id":541328,"name":"Diffuse Large B-Cell Lymphoma","url":"https://www.academia.edu/Documents/in/Diffuse_Large_B-Cell_Lymphoma?f_ri=14109"},{"id":678853,"name":"B Lymphocytes","url":"https://www.academia.edu/Documents/in/B_Lymphocytes?f_ri=14109"},{"id":1186610,"name":"DNA binding proteins","url":"https://www.academia.edu/Documents/in/DNA_binding_proteins?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_73657172" data-work_id="73657172" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/73657172/Occurrence_of_Non_Hodgkin_Lymphoma_after_the_Diagnosis_of_Persistent_Polyclonal_B_cell_Lymphocytosis">Occurrence of Non-Hodgkin Lymphoma after the Diagnosis of Persistent Polyclonal B-cell Lymphocytosis</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/73657172" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="f0af9b0f22287de7f71ad694cb8ed38f" rel="nofollow" data-download="{"attachment_id":82093347,"asset_id":73657172,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/82093347/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="49952205" href="https://independent.academia.edu/EdouardCornet">Edouard Cornet</a><script data-card-contents-for-user="49952205" type="text/json">{"id":49952205,"first_name":"Edouard","last_name":"Cornet","domain_name":"independent","page_name":"EdouardCornet","display_name":"Edouard Cornet","profile_url":"https://independent.academia.edu/EdouardCornet?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_73657172 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="73657172"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 73657172, container: ".js-paper-rank-work_73657172", }); });</script></li><li class="js-percentile-work_73657172 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 73657172; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_73657172"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_73657172 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="73657172"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 73657172; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=73657172]").text(description); $(".js-view-count-work_73657172").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_73657172").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="73657172"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">2</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a><script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=73657172]'), work: {"id":73657172,"title":"Occurrence of Non-Hodgkin Lymphoma after the Diagnosis of Persistent Polyclonal B-cell Lymphocytosis","created_at":"2022-03-13T05:36:20.343-07:00","url":"https://www.academia.edu/73657172/Occurrence_of_Non_Hodgkin_Lymphoma_after_the_Diagnosis_of_Persistent_Polyclonal_B_cell_Lymphocytosis?f_ri=14109","dom_id":"work_73657172","summary":null,"downloadable_attachments":[{"id":82093347,"asset_id":73657172,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":49952205,"first_name":"Edouard","last_name":"Cornet","domain_name":"independent","page_name":"EdouardCornet","display_name":"Edouard Cornet","profile_url":"https://independent.academia.edu/EdouardCornet?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=14109","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_71554924" data-work_id="71554924" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/71554924/Unusually_high_frequency_of_a_69_bp_deletion_within_the_carboxy_terminus_of_the_LMP1_oncogene_of_Epstein_Barr_virus_detected_in_Burkitt_s_lymphoma_of_Turkish_children">Unusually high frequency of a 69-bp deletion within the carboxy terminus of the LMP1 oncogene of Epstein–Barr virus detected in Burkitt’s lymphoma of Turkish children</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Burkitt’s lymphoma (BL) in Turkish children is commonly associated with Epstein–Barr virus (EBV) infection. The C-terminus of the latent membrane protein 1 (LMP-1) of EBV is essential for transformation and the 30-bp deletion detected in... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_71554924" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Burkitt’s lymphoma (BL) in Turkish children is commonly associated with Epstein–Barr virus (EBV) infection. The C-terminus of the latent membrane protein 1 (LMP-1) of EBV is essential for transformation and the 30-bp deletion detected in this region has been implicated to be associated with a more aggressive malignant phenotype. To understand the molecular mechanisms underlying EBV pathogenesis in BL of</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/71554924" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="4f9590eec08d32b68453758295bd3ec3" rel="nofollow" data-download="{"attachment_id":80847951,"asset_id":71554924,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/80847951/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33203651" href="https://independent.academia.edu/NurdanTacyildiz">Nurdan Tacyildiz</a><script data-card-contents-for-user="33203651" type="text/json">{"id":33203651,"first_name":"Nurdan","last_name":"Tacyildiz","domain_name":"independent","page_name":"NurdanTacyildiz","display_name":"Nurdan Tacyildiz","profile_url":"https://independent.academia.edu/NurdanTacyildiz?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_71554924 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="71554924"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 71554924, container: ".js-paper-rank-work_71554924", }); });</script></li><li class="js-percentile-work_71554924 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 71554924; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_71554924"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_71554924 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="71554924"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 71554924; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=71554924]").text(description); $(".js-view-count-work_71554924").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_71554924").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="71554924"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">16</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="7710" href="https://www.academia.edu/Documents/in/Biology">Biology</a>, <script data-card-contents-for-ri="7710" type="text/json">{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="10966" href="https://www.academia.edu/Documents/in/Turkey">Turkey</a>, <script data-card-contents-for-ri="10966" type="text/json">{"id":10966,"name":"Turkey","url":"https://www.academia.edu/Documents/in/Turkey?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a><script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=71554924]'), work: {"id":71554924,"title":"Unusually high frequency of a 69-bp deletion within the carboxy terminus of the LMP1 oncogene of Epstein–Barr virus detected in Burkitt’s lymphoma of Turkish children","created_at":"2022-02-14T20:14:03.073-08:00","url":"https://www.academia.edu/71554924/Unusually_high_frequency_of_a_69_bp_deletion_within_the_carboxy_terminus_of_the_LMP1_oncogene_of_Epstein_Barr_virus_detected_in_Burkitt_s_lymphoma_of_Turkish_children?f_ri=14109","dom_id":"work_71554924","summary":"Burkitt’s lymphoma (BL) in Turkish children is commonly associated with Epstein–Barr virus (EBV) infection. The C-terminus of the latent membrane protein 1 (LMP-1) of EBV is essential for transformation and the 30-bp deletion detected in this region has been implicated to be associated with a more aggressive malignant phenotype. To understand the molecular mechanisms underlying EBV pathogenesis in BL of","downloadable_attachments":[{"id":80847951,"asset_id":71554924,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33203651,"first_name":"Nurdan","last_name":"Tacyildiz","domain_name":"independent","page_name":"NurdanTacyildiz","display_name":"Nurdan Tacyildiz","profile_url":"https://independent.academia.edu/NurdanTacyildiz?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=14109","nofollow":false},{"id":10966,"name":"Turkey","url":"https://www.academia.edu/Documents/in/Turkey?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=14109","nofollow":false},{"id":35637,"name":"Molecular Mechanics","url":"https://www.academia.edu/Documents/in/Molecular_Mechanics?f_ri=14109"},{"id":48458,"name":"High Frequency","url":"https://www.academia.edu/Documents/in/High_Frequency?f_ri=14109"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=14109"},{"id":118339,"name":"Polymerase Chain Reaction","url":"https://www.academia.edu/Documents/in/Polymerase_Chain_Reaction?f_ri=14109"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109"},{"id":315624,"name":"Epstein-Barr virus","url":"https://www.academia.edu/Documents/in/Epstein-Barr_virus?f_ri=14109"},{"id":372410,"name":"Genotype","url":"https://www.academia.edu/Documents/in/Genotype?f_ri=14109"},{"id":759403,"name":"Gel electrophoresis","url":"https://www.academia.edu/Documents/in/Gel_electrophoresis?f_ri=14109"},{"id":809881,"name":"Amino Acid Sequence","url":"https://www.academia.edu/Documents/in/Amino_Acid_Sequence?f_ri=14109"},{"id":809882,"name":"Base Sequence","url":"https://www.academia.edu/Documents/in/Base_Sequence?f_ri=14109"},{"id":2274872,"name":"DNA sequence","url":"https://www.academia.edu/Documents/in/DNA_sequence?f_ri=14109"},{"id":2467566,"name":"Molecular Sequence Data","url":"https://www.academia.edu/Documents/in/Molecular_Sequence_Data?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_38956892" data-work_id="38956892" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/38956892/Suppression_of_c_Myc_using_10058_F4_exerts_caspase_3_dependent_apoptosis_and_intensifies_the_antileukemic_effect_of_vincristine_in_pre_B_acute_lymphoblastic_leukemia_cells">Suppression of c-Myc using 10058-F4 exerts caspase-3-dependent apoptosis and intensifies the antileukemic effect of vincristine in pre-B acute lymphoblastic leukemia cells</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Despite an old history behind the identification of the leading role of c-Myc in leukemogenesis, the road to constructing a therapeutic perspective for this molecule in acute lymphoblastic leukemia (ALL) is yet mesmerizing. This study was... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_38956892" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Despite an old history behind the identification of the leading role of c-Myc in leukemogenesis, the road to constructing a therapeutic perspective for this molecule in acute lymphoblastic leukemia (ALL) is yet mesmerizing. This study was designed to provide a better outlook for the anticancer property of 10058-F4, an appealing inhibitor of c-Myc, in pre-B ALL cell lines either in the context of monotherapy or in combination with chemotherapeutic drugs. Our results declared that abrogation of c-Myc decreased the proliferative capacity of pre-B ALL-derived cells through halting the transition of the cells from G1 phase, and reducing the replicative potential of both REH and Nalm-6 cells, at least partly, through c-Myc-mediated suppression of human telomerase reverse transcrip-tase. Moreover, 10058-F4 potently induced a caspase-3-dependent apoptosis in pre-B ALL cells via shifting the balance between pro-and anti-apoptotic target genes. Although the inhibition of PI3Kδ using Idelalisib upregulated the messenger RNA expression of autophagy-related genes in 10058-F4-treated cells, treatment with autophagy inhibitor chloroquine decreased viability of the cells, either as a single agent or in combination with Idelalisib and/or 10058-F4; suggesting that the activation of autophagy in pre-B ALL cells could blunt apoptotic events and attenuate anticancer effect of both c-Myc and PI3K inhibitors. Finally, the results of our synergistic experiments delineated that 10058-F4 produced a synergistic effect with vincristine and provided an enhanced therapeutic efficacy in ALL cells, highlighting that c-Myc oncoprotein could be a bona fide target for the treatment of ALL. K E Y W O R D S acute lymphoblastic leukemia, autophagy, c-Myc, PI3K signaling pathway, 10058-F4</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/38956892" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="2ef1ab14978e3f39ee1f60aafdab7463" rel="nofollow" data-download="{"attachment_id":59059609,"asset_id":38956892,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/59059609/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="110673521" href="https://indiana.academia.edu/niknamriyahi">niknam riyahi</a><script data-card-contents-for-user="110673521" type="text/json">{"id":110673521,"first_name":"niknam","last_name":"riyahi","domain_name":"indiana","page_name":"niknamriyahi","display_name":"niknam riyahi","profile_url":"https://indiana.academia.edu/niknamriyahi?f_ri=14109","photo":"https://0.academia-photos.com/110673521/26139140/24753901/s65_niknam.riyahi.jpg"}</script></span></span></li><li class="js-paper-rank-work_38956892 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="38956892"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 38956892, container: ".js-paper-rank-work_38956892", }); });</script></li><li class="js-percentile-work_38956892 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 38956892; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_38956892"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_38956892 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="38956892"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 38956892; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=38956892]").text(description); $(".js-view-count-work_38956892").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_38956892").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="38956892"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">2</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="6021" href="https://www.academia.edu/Documents/in/Cancer">Cancer</a>, <script data-card-contents-for-ri="6021" type="text/json">{"id":6021,"name":"Cancer","url":"https://www.academia.edu/Documents/in/Cancer?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a><script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=38956892]'), work: {"id":38956892,"title":"Suppression of c-Myc using 10058-F4 exerts caspase-3-dependent apoptosis and intensifies the antileukemic effect of vincristine in pre-B acute lymphoblastic leukemia cells","created_at":"2019-04-28T02:38:53.759-07:00","url":"https://www.academia.edu/38956892/Suppression_of_c_Myc_using_10058_F4_exerts_caspase_3_dependent_apoptosis_and_intensifies_the_antileukemic_effect_of_vincristine_in_pre_B_acute_lymphoblastic_leukemia_cells?f_ri=14109","dom_id":"work_38956892","summary":"Despite an old history behind the identification of the leading role of c-Myc in leukemogenesis, the road to constructing a therapeutic perspective for this molecule in acute lymphoblastic leukemia (ALL) is yet mesmerizing. This study was designed to provide a better outlook for the anticancer property of 10058-F4, an appealing inhibitor of c-Myc, in pre-B ALL cell lines either in the context of monotherapy or in combination with chemotherapeutic drugs. Our results declared that abrogation of c-Myc decreased the proliferative capacity of pre-B ALL-derived cells through halting the transition of the cells from G1 phase, and reducing the replicative potential of both REH and Nalm-6 cells, at least partly, through c-Myc-mediated suppression of human telomerase reverse transcrip-tase. Moreover, 10058-F4 potently induced a caspase-3-dependent apoptosis in pre-B ALL cells via shifting the balance between pro-and anti-apoptotic target genes. Although the inhibition of PI3Kδ using Idelalisib upregulated the messenger RNA expression of autophagy-related genes in 10058-F4-treated cells, treatment with autophagy inhibitor chloroquine decreased viability of the cells, either as a single agent or in combination with Idelalisib and/or 10058-F4; suggesting that the activation of autophagy in pre-B ALL cells could blunt apoptotic events and attenuate anticancer effect of both c-Myc and PI3K inhibitors. Finally, the results of our synergistic experiments delineated that 10058-F4 produced a synergistic effect with vincristine and provided an enhanced therapeutic efficacy in ALL cells, highlighting that c-Myc oncoprotein could be a bona fide target for the treatment of ALL. K E Y W O R D S acute lymphoblastic leukemia, autophagy, c-Myc, PI3K signaling pathway, 10058-F4","downloadable_attachments":[{"id":59059609,"asset_id":38956892,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":110673521,"first_name":"niknam","last_name":"riyahi","domain_name":"indiana","page_name":"niknamriyahi","display_name":"niknam riyahi","profile_url":"https://indiana.academia.edu/niknamriyahi?f_ri=14109","photo":"https://0.academia-photos.com/110673521/26139140/24753901/s65_niknam.riyahi.jpg"}],"research_interests":[{"id":6021,"name":"Cancer","url":"https://www.academia.edu/Documents/in/Cancer?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_8083653" data-work_id="8083653" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/8083653/Vascular_and_Neoplastic_Risk_in_a_Large_Cohort_of_Patients_With_Polycythemia_Vera">Vascular and Neoplastic Risk in a Large Cohort of Patients With Polycythemia Vera</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/8083653" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="65122158ac772e3167edcf8281b92954" rel="nofollow" data-download="{"attachment_id":48219701,"asset_id":8083653,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48219701/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="15630791" href="https://independent.academia.edu/AnaVillegas2">Ana Villegas</a><script data-card-contents-for-user="15630791" type="text/json">{"id":15630791,"first_name":"Ana","last_name":"Villegas","domain_name":"independent","page_name":"AnaVillegas2","display_name":"Ana Villegas","profile_url":"https://independent.academia.edu/AnaVillegas2?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_8083653 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="8083653"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 8083653, container: ".js-paper-rank-work_8083653", }); });</script></li><li class="js-percentile-work_8083653 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 8083653; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_8083653"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_8083653 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="8083653"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 8083653; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=8083653]").text(description); $(".js-view-count-work_8083653").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_8083653").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="8083653"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">18</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="10610" href="https://www.academia.edu/Documents/in/Survival_Analysis">Survival Analysis</a>, <script data-card-contents-for-ri="10610" type="text/json">{"id":10610,"name":"Survival Analysis","url":"https://www.academia.edu/Documents/in/Survival_Analysis?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="59057" href="https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia">Acute Myeloid Leukemia</a>, <script data-card-contents-for-ri="59057" type="text/json">{"id":59057,"name":"Acute Myeloid Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a><script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=8083653]'), work: {"id":8083653,"title":"Vascular and Neoplastic Risk in a Large Cohort of Patients With Polycythemia Vera","created_at":"2014-08-25T15:41:34.049-07:00","url":"https://www.academia.edu/8083653/Vascular_and_Neoplastic_Risk_in_a_Large_Cohort_of_Patients_With_Polycythemia_Vera?f_ri=14109","dom_id":"work_8083653","summary":null,"downloadable_attachments":[{"id":48219701,"asset_id":8083653,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":15630791,"first_name":"Ana","last_name":"Villegas","domain_name":"independent","page_name":"AnaVillegas2","display_name":"Ana Villegas","profile_url":"https://independent.academia.edu/AnaVillegas2?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":10610,"name":"Survival Analysis","url":"https://www.academia.edu/Documents/in/Survival_Analysis?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":59057,"name":"Acute Myeloid Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia?f_ri=14109","nofollow":false},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=14109","nofollow":false},{"id":72821,"name":"Low Dose","url":"https://www.academia.edu/Documents/in/Low_Dose?f_ri=14109"},{"id":99708,"name":"Clinical","url":"https://www.academia.edu/Documents/in/Clinical?f_ri=14109"},{"id":115895,"name":"Clinical oncology","url":"https://www.academia.edu/Documents/in/Clinical_oncology?f_ri=14109"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=14109"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=14109"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=14109"},{"id":496063,"name":"Thrombosis","url":"https://www.academia.edu/Documents/in/Thrombosis?f_ri=14109"},{"id":559242,"name":"Cardiovascular Diseases","url":"https://www.academia.edu/Documents/in/Cardiovascular_Diseases?f_ri=14109"},{"id":572754,"name":"Antiplatelet Therapy","url":"https://www.academia.edu/Documents/in/Antiplatelet_Therapy?f_ri=14109"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=14109"},{"id":982035,"name":"International Collaboration","url":"https://www.academia.edu/Documents/in/International_Collaboration?f_ri=14109"},{"id":1680434,"name":"Mortality rate","url":"https://www.academia.edu/Documents/in/Mortality_rate?f_ri=14109"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=14109"},{"id":1993786,"name":"Cumulant","url":"https://www.academia.edu/Documents/in/Cumulant?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_10689523" data-work_id="10689523" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/10689523/Studies_of_Mortality_of_Atomic_Bomb_Survivors_Report_13_Solid_Cancer_and_Noncancer_Disease_Mortality_1950_1997">Studies of Mortality of Atomic Bomb Survivors. Report 13: Solid Cancer and Noncancer Disease Mortality: 1950–1997</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/10689523" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="e89b6956f7f209844a9c9ba68de446bd" rel="nofollow" data-download="{"attachment_id":47202757,"asset_id":10689523,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/47202757/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="26087422" href="https://independent.academia.edu/DonaldPierce">Donald Pierce</a><script data-card-contents-for-user="26087422" type="text/json">{"id":26087422,"first_name":"Donald","last_name":"Pierce","domain_name":"independent","page_name":"DonaldPierce","display_name":"Donald Pierce","profile_url":"https://independent.academia.edu/DonaldPierce?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_10689523 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="10689523"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 10689523, container: ".js-paper-rank-work_10689523", }); });</script></li><li class="js-percentile-work_10689523 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 10689523; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_10689523"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_10689523 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="10689523"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 10689523; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=10689523]").text(description); $(".js-view-count-work_10689523").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_10689523").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="10689523"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">35</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="1328" href="https://www.academia.edu/Documents/in/Radiation">Radiation</a>, <script data-card-contents-for-ri="1328" type="text/json">{"id":1328,"name":"Radiation","url":"https://www.academia.edu/Documents/in/Radiation?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="4507" href="https://www.academia.edu/Documents/in/Nuclear_Weapons">Nuclear Weapons</a>, <script data-card-contents-for-ri="4507" type="text/json">{"id":4507,"name":"Nuclear Weapons","url":"https://www.academia.edu/Documents/in/Nuclear_Weapons?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="6177" href="https://www.academia.edu/Documents/in/Modeling">Modeling</a>, <script data-card-contents-for-ri="6177" type="text/json">{"id":6177,"name":"Modeling","url":"https://www.academia.edu/Documents/in/Modeling?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="8207" href="https://www.academia.edu/Documents/in/Risk">Risk</a><script data-card-contents-for-ri="8207" type="text/json">{"id":8207,"name":"Risk","url":"https://www.academia.edu/Documents/in/Risk?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=10689523]'), work: {"id":10689523,"title":"Studies of Mortality of Atomic Bomb Survivors. Report 13: Solid Cancer and Noncancer Disease Mortality: 1950–1997","created_at":"2015-02-10T17:36:27.436-08:00","url":"https://www.academia.edu/10689523/Studies_of_Mortality_of_Atomic_Bomb_Survivors_Report_13_Solid_Cancer_and_Noncancer_Disease_Mortality_1950_1997?f_ri=14109","dom_id":"work_10689523","summary":null,"downloadable_attachments":[{"id":47202757,"asset_id":10689523,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":26087422,"first_name":"Donald","last_name":"Pierce","domain_name":"independent","page_name":"DonaldPierce","display_name":"Donald Pierce","profile_url":"https://independent.academia.edu/DonaldPierce?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":1328,"name":"Radiation","url":"https://www.academia.edu/Documents/in/Radiation?f_ri=14109","nofollow":false},{"id":4507,"name":"Nuclear Weapons","url":"https://www.academia.edu/Documents/in/Nuclear_Weapons?f_ri=14109","nofollow":false},{"id":6177,"name":"Modeling","url":"https://www.academia.edu/Documents/in/Modeling?f_ri=14109","nofollow":false},{"id":8207,"name":"Risk","url":"https://www.academia.edu/Documents/in/Risk?f_ri=14109","nofollow":false},{"id":10610,"name":"Survival Analysis","url":"https://www.academia.edu/Documents/in/Survival_Analysis?f_ri=14109"},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109"},{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=14109"},{"id":17158,"name":"Japan","url":"https://www.academia.edu/Documents/in/Japan?f_ri=14109"},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109"},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=14109"},{"id":50711,"name":"Risk Analysis","url":"https://www.academia.edu/Documents/in/Risk_Analysis?f_ri=14109"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=14109"},{"id":82641,"name":"Survivors","url":"https://www.academia.edu/Documents/in/Survivors?f_ri=14109"},{"id":106145,"name":"Classification","url":"https://www.academia.edu/Documents/in/Classification?f_ri=14109"},{"id":118582,"name":"Physical sciences","url":"https://www.academia.edu/Documents/in/Physical_sciences?f_ri=14109"},{"id":131185,"name":"Cohort Study","url":"https://www.academia.edu/Documents/in/Cohort_Study?f_ri=14109"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=14109"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=14109"},{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies?f_ri=14109"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=14109"},{"id":212758,"name":"Trend Analysis","url":"https://www.academia.edu/Documents/in/Trend_Analysis?f_ri=14109"},{"id":253560,"name":"Newborn Infant","url":"https://www.academia.edu/Documents/in/Newborn_Infant?f_ri=14109"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=14109"},{"id":335365,"name":"Radiometry","url":"https://www.academia.edu/Documents/in/Radiometry?f_ri=14109"},{"id":389506,"name":"Radiation Dose","url":"https://www.academia.edu/Documents/in/Radiation_Dose?f_ri=14109"},{"id":413192,"name":"Sex Factors","url":"https://www.academia.edu/Documents/in/Sex_Factors?f_ri=14109"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=14109"},{"id":537657,"name":"Radioactive contamination","url":"https://www.academia.edu/Documents/in/Radioactive_contamination?f_ri=14109"},{"id":546419,"name":"Age Factors","url":"https://www.academia.edu/Documents/in/Age_Factors?f_ri=14109"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=14109"},{"id":622589,"name":"Risk Assessment","url":"https://www.academia.edu/Documents/in/Risk_Assessment-2?f_ri=14109"},{"id":1272981,"name":"Proportional Hazards Models","url":"https://www.academia.edu/Documents/in/Proportional_Hazards_Models?f_ri=14109"},{"id":1512198,"name":"Nuclear Warfare","url":"https://www.academia.edu/Documents/in/Nuclear_Warfare?f_ri=14109"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=14109"},{"id":2489700,"name":"Child preschool","url":"https://www.academia.edu/Documents/in/Child_preschool?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_10737641" data-work_id="10737641" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/10737641/Novel_JAK2_rearrangement_resulting_from_a_t_9_22_p24_q11_2_in_B_acute_lymphoblastic_leukemia">Novel JAK2 rearrangement resulting from a t(9;22)(p24;q11.2) in B-acute lymphoblastic leukemia</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/10737641" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="34425b9938943ac039296e04de97bfd9" rel="nofollow" data-download="{"attachment_id":47165923,"asset_id":10737641,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/47165923/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="26173292" href="https://independent.academia.edu/MatthewHiemenz">Matthew Hiemenz</a><script data-card-contents-for-user="26173292" type="text/json">{"id":26173292,"first_name":"Matthew","last_name":"Hiemenz","domain_name":"independent","page_name":"MatthewHiemenz","display_name":"Matthew Hiemenz","profile_url":"https://independent.academia.edu/MatthewHiemenz?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_10737641 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="10737641"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 10737641, container: ".js-paper-rank-work_10737641", }); });</script></li><li class="js-percentile-work_10737641 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 10737641; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_10737641"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_10737641 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="10737641"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 10737641; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=10737641]").text(description); $(".js-view-count-work_10737641").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_10737641").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="10737641"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">4</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a>, <script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="1630613" href="https://www.academia.edu/Documents/in/Acute_Lymphoblastic_Leukemia">Acute Lymphoblastic Leukemia</a><script data-card-contents-for-ri="1630613" type="text/json">{"id":1630613,"name":"Acute Lymphoblastic Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Lymphoblastic_Leukemia?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=10737641]'), work: {"id":10737641,"title":"Novel JAK2 rearrangement resulting from a t(9;22)(p24;q11.2) in B-acute lymphoblastic leukemia","created_at":"2015-02-12T07:33:13.863-08:00","url":"https://www.academia.edu/10737641/Novel_JAK2_rearrangement_resulting_from_a_t_9_22_p24_q11_2_in_B_acute_lymphoblastic_leukemia?f_ri=14109","dom_id":"work_10737641","summary":null,"downloadable_attachments":[{"id":47165923,"asset_id":10737641,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":26173292,"first_name":"Matthew","last_name":"Hiemenz","domain_name":"independent","page_name":"MatthewHiemenz","display_name":"Matthew Hiemenz","profile_url":"https://independent.academia.edu/MatthewHiemenz?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109","nofollow":false},{"id":1630613,"name":"Acute Lymphoblastic Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Lymphoblastic_Leukemia?f_ri=14109","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_26707280" data-work_id="26707280" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/26707280/Donor_Killer_Immunoglobulin_Like_Receptor_KIR_Genotype_Patient_Cognate_KIR_Ligand_Combination_and_Antithymocyte_Globulin_Preadministration_Are_Critical_Factors_in_Outcome_of_HLA_C_KIR_Ligand_Mismatched_T_Cell_Replete_Unrelated_Bone_Marrow_Transplantation">Donor Killer Immunoglobulin-Like Receptor (KIR) Genotype-Patient Cognate KIR Ligand Combination and Antithymocyte Globulin Preadministration Are Critical Factors in Outcome of HLA-C-KIR Ligand-Mismatched T Cell–Replete Unrelated Bone Marrow Transplantation</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/26707280" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="cb26bbb3b826e6210cbbecf39f04f297" rel="nofollow" data-download="{"attachment_id":46989268,"asset_id":26707280,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46989268/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="50700474" href="https://independent.academia.edu/MinokoTakanashi">Minoko Takanashi</a><script data-card-contents-for-user="50700474" type="text/json">{"id":50700474,"first_name":"Minoko","last_name":"Takanashi","domain_name":"independent","page_name":"MinokoTakanashi","display_name":"Minoko Takanashi","profile_url":"https://independent.academia.edu/MinokoTakanashi?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_26707280 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="26707280"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 26707280, container: ".js-paper-rank-work_26707280", }); });</script></li><li class="js-percentile-work_26707280 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 26707280; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_26707280"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_26707280 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="26707280"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 26707280; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=26707280]").text(description); $(".js-view-count-work_26707280").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_26707280").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="26707280"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">14</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="10610" href="https://www.academia.edu/Documents/in/Survival_Analysis">Survival Analysis</a>, <script data-card-contents-for-ri="10610" type="text/json">{"id":10610,"name":"Survival Analysis","url":"https://www.academia.edu/Documents/in/Survival_Analysis?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="41482" href="https://www.academia.edu/Documents/in/Multivariate_Analysis">Multivariate Analysis</a>, <script data-card-contents-for-ri="41482" type="text/json">{"id":41482,"name":"Multivariate Analysis","url":"https://www.academia.edu/Documents/in/Multivariate_Analysis?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="70247" href="https://www.academia.edu/Documents/in/Natural_Killer_cells">Natural Killer cells</a><script data-card-contents-for-ri="70247" type="text/json">{"id":70247,"name":"Natural Killer cells","url":"https://www.academia.edu/Documents/in/Natural_Killer_cells?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=26707280]'), work: {"id":26707280,"title":"Donor Killer Immunoglobulin-Like Receptor (KIR) Genotype-Patient Cognate KIR Ligand Combination and Antithymocyte Globulin Preadministration Are Critical Factors in Outcome of HLA-C-KIR Ligand-Mismatched T Cell–Replete Unrelated Bone Marrow Transplantation","created_at":"2016-07-03T19:57:06.143-07:00","url":"https://www.academia.edu/26707280/Donor_Killer_Immunoglobulin_Like_Receptor_KIR_Genotype_Patient_Cognate_KIR_Ligand_Combination_and_Antithymocyte_Globulin_Preadministration_Are_Critical_Factors_in_Outcome_of_HLA_C_KIR_Ligand_Mismatched_T_Cell_Replete_Unrelated_Bone_Marrow_Transplantation?f_ri=14109","dom_id":"work_26707280","summary":null,"downloadable_attachments":[{"id":46989268,"asset_id":26707280,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":50700474,"first_name":"Minoko","last_name":"Takanashi","domain_name":"independent","page_name":"MinokoTakanashi","display_name":"Minoko Takanashi","profile_url":"https://independent.academia.edu/MinokoTakanashi?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":10610,"name":"Survival Analysis","url":"https://www.academia.edu/Documents/in/Survival_Analysis?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":41482,"name":"Multivariate Analysis","url":"https://www.academia.edu/Documents/in/Multivariate_Analysis?f_ri=14109","nofollow":false},{"id":70247,"name":"Natural Killer cells","url":"https://www.academia.edu/Documents/in/Natural_Killer_cells?f_ri=14109","nofollow":false},{"id":86952,"name":"Haplotypes","url":"https://www.academia.edu/Documents/in/Haplotypes?f_ri=14109"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109"},{"id":354937,"name":"Bone Marrow Transplantation","url":"https://www.academia.edu/Documents/in/Bone_Marrow_Transplantation?f_ri=14109"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=14109"},{"id":1222191,"name":"Ligands","url":"https://www.academia.edu/Documents/in/Ligands?f_ri=14109"},{"id":1225372,"name":"Overall Survival","url":"https://www.academia.edu/Documents/in/Overall_Survival?f_ri=14109"},{"id":1274831,"name":"NK Cell","url":"https://www.academia.edu/Documents/in/NK_Cell?f_ri=14109"},{"id":1521551,"name":"Graft-Versus-Host Disease","url":"https://www.academia.edu/Documents/in/Graft-Versus-Host_Disease?f_ri=14109"},{"id":1587858,"name":"Confidence Interval","url":"https://www.academia.edu/Documents/in/Confidence_Interval?f_ri=14109"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_25654833" data-work_id="25654833" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/25654833/Results_of_decitabine_therapy_in_the_accelerated_and_blastic_phases_of_chronic_myelogenous_leukemia">Results of decitabine therapy in the accelerated and blastic phases of chronic myelogenous leukemia</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/25654833" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="fbe5fb53bb12acff5db8263f70ace22b" rel="nofollow" data-download="{"attachment_id":45992417,"asset_id":25654833,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45992417/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="49315815" href="https://mdanderson.academia.edu/StevenKornblau">Steven Kornblau</a><script data-card-contents-for-user="49315815" type="text/json">{"id":49315815,"first_name":"Steven","last_name":"Kornblau","domain_name":"mdanderson","page_name":"StevenKornblau","display_name":"Steven Kornblau","profile_url":"https://mdanderson.academia.edu/StevenKornblau?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_25654833 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="25654833"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 25654833, container: ".js-paper-rank-work_25654833", }); });</script></li><li class="js-percentile-work_25654833 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 25654833; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_25654833"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_25654833 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="25654833"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 25654833; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=25654833]").text(description); $(".js-view-count-work_25654833").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_25654833").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="25654833"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="23163" href="https://www.academia.edu/Documents/in/Stem_Cell">Stem Cell</a>, <script data-card-contents-for-ri="23163" type="text/json">{"id":23163,"name":"Stem Cell","url":"https://www.academia.edu/Documents/in/Stem_Cell?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="59057" href="https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia">Acute Myeloid Leukemia</a>, <script data-card-contents-for-ri="59057" type="text/json">{"id":59057,"name":"Acute Myeloid Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="67422" href="https://www.academia.edu/Documents/in/Myelodysplastic_Syndrome">Myelodysplastic Syndrome</a><script data-card-contents-for-ri="67422" type="text/json">{"id":67422,"name":"Myelodysplastic Syndrome","url":"https://www.academia.edu/Documents/in/Myelodysplastic_Syndrome?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=25654833]'), work: {"id":25654833,"title":"Results of decitabine therapy in the accelerated and blastic phases of chronic myelogenous leukemia","created_at":"2016-05-27T05:48:24.811-07:00","url":"https://www.academia.edu/25654833/Results_of_decitabine_therapy_in_the_accelerated_and_blastic_phases_of_chronic_myelogenous_leukemia?f_ri=14109","dom_id":"work_25654833","summary":null,"downloadable_attachments":[{"id":45992417,"asset_id":25654833,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":49315815,"first_name":"Steven","last_name":"Kornblau","domain_name":"mdanderson","page_name":"StevenKornblau","display_name":"Steven Kornblau","profile_url":"https://mdanderson.academia.edu/StevenKornblau?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":23163,"name":"Stem Cell","url":"https://www.academia.edu/Documents/in/Stem_Cell?f_ri=14109","nofollow":false},{"id":59057,"name":"Acute Myeloid Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia?f_ri=14109","nofollow":false},{"id":67422,"name":"Myelodysplastic Syndrome","url":"https://www.academia.edu/Documents/in/Myelodysplastic_Syndrome?f_ri=14109","nofollow":false},{"id":236576,"name":"IT Value","url":"https://www.academia.edu/Documents/in/IT_Value?f_ri=14109"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=14109"},{"id":698785,"name":"Side Effect","url":"https://www.academia.edu/Documents/in/Side_Effect?f_ri=14109"},{"id":1815217,"name":"Chronic myelogenous leukemia","url":"https://www.academia.edu/Documents/in/Chronic_myelogenous_leukemia?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_12904454" data-work_id="12904454" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/12904454/Chronic_lymphocytic_leukemia_presenting_with_symptomatic_peritoneal_infiltration">Chronic lymphocytic leukemia presenting with symptomatic peritoneal infiltration</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/12904454" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="bc4136972b95ba8a127d666ab3769367" rel="nofollow" data-download="{"attachment_id":45856439,"asset_id":12904454,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45856439/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32065585" href="https://unina2.academia.edu/SalvatoreGuastafierro">Salvatore Guastafierro</a><script data-card-contents-for-user="32065585" type="text/json">{"id":32065585,"first_name":"Salvatore","last_name":"Guastafierro","domain_name":"unina2","page_name":"SalvatoreGuastafierro","display_name":"Salvatore Guastafierro","profile_url":"https://unina2.academia.edu/SalvatoreGuastafierro?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_12904454 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="12904454"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 12904454, container: ".js-paper-rank-work_12904454", }); });</script></li><li class="js-percentile-work_12904454 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 12904454; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_12904454"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_12904454 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="12904454"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 12904454; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=12904454]").text(description); $(".js-view-count-work_12904454").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_12904454").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="12904454"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="6599" href="https://www.academia.edu/Documents/in/Flow_Cytometry">Flow Cytometry</a>, <script data-card-contents-for-ri="6599" type="text/json">{"id":6599,"name":"Flow Cytometry","url":"https://www.academia.edu/Documents/in/Flow_Cytometry?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="37826" href="https://www.academia.edu/Documents/in/Biopsy">Biopsy</a>, <script data-card-contents-for-ri="37826" type="text/json">{"id":37826,"name":"Biopsy","url":"https://www.academia.edu/Documents/in/Biopsy?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="82976" href="https://www.academia.edu/Documents/in/Chronic_Lymphocytic_Leukemia">Chronic Lymphocytic Leukemia</a><script data-card-contents-for-ri="82976" type="text/json">{"id":82976,"name":"Chronic Lymphocytic Leukemia","url":"https://www.academia.edu/Documents/in/Chronic_Lymphocytic_Leukemia?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=12904454]'), work: {"id":12904454,"title":"Chronic lymphocytic leukemia presenting with symptomatic peritoneal infiltration","created_at":"2015-06-10T08:32:31.207-07:00","url":"https://www.academia.edu/12904454/Chronic_lymphocytic_leukemia_presenting_with_symptomatic_peritoneal_infiltration?f_ri=14109","dom_id":"work_12904454","summary":null,"downloadable_attachments":[{"id":45856439,"asset_id":12904454,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32065585,"first_name":"Salvatore","last_name":"Guastafierro","domain_name":"unina2","page_name":"SalvatoreGuastafierro","display_name":"Salvatore Guastafierro","profile_url":"https://unina2.academia.edu/SalvatoreGuastafierro?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":6599,"name":"Flow Cytometry","url":"https://www.academia.edu/Documents/in/Flow_Cytometry?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":37826,"name":"Biopsy","url":"https://www.academia.edu/Documents/in/Biopsy?f_ri=14109","nofollow":false},{"id":82976,"name":"Chronic Lymphocytic Leukemia","url":"https://www.academia.edu/Documents/in/Chronic_Lymphocytic_Leukemia?f_ri=14109","nofollow":false},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=14109"},{"id":1180715,"name":"Abdominal Pain","url":"https://www.academia.edu/Documents/in/Abdominal_Pain?f_ri=14109"},{"id":1311469,"name":"Blood cells","url":"https://www.academia.edu/Documents/in/Blood_cells?f_ri=14109"},{"id":1478654,"name":"Peritoneal Cavity","url":"https://www.academia.edu/Documents/in/Peritoneal_Cavity?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_13654631" data-work_id="13654631" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13654631/Sinusal_bradycardia_after_receiving_intermediate_or_high_dose_cytarabine_four_cases_from_a_single_institution">Sinusal bradycardia after receiving intermediate or high dose cytarabine: four cases from a single institution</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13654631" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="c9306c89182e31476c2b9cf16789b5a3" rel="nofollow" data-download="{"attachment_id":45100610,"asset_id":13654631,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45100610/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32808718" href="https://independent.academia.edu/EmanueleAngelucci">Emanuele Angelucci</a><script data-card-contents-for-user="32808718" type="text/json">{"id":32808718,"first_name":"Emanuele","last_name":"Angelucci","domain_name":"independent","page_name":"EmanueleAngelucci","display_name":"Emanuele Angelucci","profile_url":"https://independent.academia.edu/EmanueleAngelucci?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_13654631 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="13654631"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 13654631, container: ".js-paper-rank-work_13654631", }); });</script></li><li class="js-percentile-work_13654631 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 13654631; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_13654631"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_13654631 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="13654631"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 13654631; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=13654631]").text(description); $(".js-view-count-work_13654631").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_13654631").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="13654631"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">7</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="588" href="https://www.academia.edu/Documents/in/Nursing">Nursing</a>, <script data-card-contents-for-ri="588" type="text/json">{"id":588,"name":"Nursing","url":"https://www.academia.edu/Documents/in/Nursing?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="12426" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a>, <script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a><script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=13654631]'), work: {"id":13654631,"title":"Sinusal bradycardia after receiving intermediate or high dose cytarabine: four cases from a single institution","created_at":"2015-07-05T08:05:38.931-07:00","url":"https://www.academia.edu/13654631/Sinusal_bradycardia_after_receiving_intermediate_or_high_dose_cytarabine_four_cases_from_a_single_institution?f_ri=14109","dom_id":"work_13654631","summary":null,"downloadable_attachments":[{"id":45100610,"asset_id":13654631,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32808718,"first_name":"Emanuele","last_name":"Angelucci","domain_name":"independent","page_name":"EmanueleAngelucci","display_name":"Emanuele Angelucci","profile_url":"https://independent.academia.edu/EmanueleAngelucci?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":588,"name":"Nursing","url":"https://www.academia.edu/Documents/in/Nursing?f_ri=14109","nofollow":false},{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=14109"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=14109"},{"id":2003391,"name":"Bradycardia","url":"https://www.academia.edu/Documents/in/Bradycardia?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_22923909" data-work_id="22923909" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/22923909/Inv_11_q21q23_fuses_MLL_to_the_Notch_co_activator_mastermind_like_2_in_secondary_T_cell_acute_lymphoblastic_leukemia">Inv(11)(q21q23) fuses MLL to the Notch co-activator mastermind-like 2 in secondary T-cell acute lymphoblastic leukemia</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/22923909" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="3f7f4e8863caa554b5cb72086aa58f12" rel="nofollow" data-download="{"attachment_id":43457633,"asset_id":22923909,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/43457633/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="44615164" href="https://independent.academia.edu/JochenHarbott">Jochen Harbott</a><script data-card-contents-for-user="44615164" type="text/json">{"id":44615164,"first_name":"Jochen","last_name":"Harbott","domain_name":"independent","page_name":"JochenHarbott","display_name":"Jochen Harbott","profile_url":"https://independent.academia.edu/JochenHarbott?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_22923909 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="22923909"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 22923909, container: ".js-paper-rank-work_22923909", }); });</script></li><li class="js-percentile-work_22923909 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 22923909; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_22923909"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_22923909 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="22923909"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 22923909; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=22923909]").text(description); $(".js-view-count-work_22923909").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_22923909").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="22923909"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">7</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="23323" href="https://www.academia.edu/Documents/in/Transcription_Factors">Transcription Factors</a>, <script data-card-contents-for-ri="23323" type="text/json">{"id":23323,"name":"Transcription Factors","url":"https://www.academia.edu/Documents/in/Transcription_Factors?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a><script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=22923909]'), work: {"id":22923909,"title":"Inv(11)(q21q23) fuses MLL to the Notch co-activator mastermind-like 2 in secondary T-cell acute lymphoblastic leukemia","created_at":"2016-03-07T04:50:05.751-08:00","url":"https://www.academia.edu/22923909/Inv_11_q21q23_fuses_MLL_to_the_Notch_co_activator_mastermind_like_2_in_secondary_T_cell_acute_lymphoblastic_leukemia?f_ri=14109","dom_id":"work_22923909","summary":null,"downloadable_attachments":[{"id":43457633,"asset_id":22923909,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":44615164,"first_name":"Jochen","last_name":"Harbott","domain_name":"independent","page_name":"JochenHarbott","display_name":"Jochen Harbott","profile_url":"https://independent.academia.edu/JochenHarbott?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false},{"id":23323,"name":"Transcription Factors","url":"https://www.academia.edu/Documents/in/Transcription_Factors?f_ri=14109","nofollow":false},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109","nofollow":false},{"id":1186610,"name":"DNA binding proteins","url":"https://www.academia.edu/Documents/in/DNA_binding_proteins?f_ri=14109"},{"id":1630613,"name":"Acute Lymphoblastic Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Lymphoblastic_Leukemia?f_ri=14109"},{"id":2374838,"name":"Hematopoietic Stem Cell Transplantation","url":"https://www.academia.edu/Documents/in/Hematopoietic_Stem_Cell_Transplantation?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_16464611 coauthored" data-work_id="16464611" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/16464611/Quantitative_evaluation_of_p16INK4a_promoter_methylation_using_pyrosequencing_in_de_novo_diffuse_large_B_cell_lymphoma">Quantitative evaluation of p16INK4a promoter methylation using pyrosequencing in de novo diffuse large B-cell lymphoma</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/16464611" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="e0dd2959a96bbda909ce4f2226c89aa2" rel="nofollow" data-download="{"attachment_id":42484729,"asset_id":16464611,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42484729/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="35662778" href="https://uppsala.academia.edu/RichardRosenquist">Richard Rosenquist</a><script data-card-contents-for-user="35662778" type="text/json">{"id":35662778,"first_name":"Richard","last_name":"Rosenquist","domain_name":"uppsala","page_name":"RichardRosenquist","display_name":"Richard Rosenquist","profile_url":"https://uppsala.academia.edu/RichardRosenquist?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-16464611">+2</span><div class="hidden js-additional-users-16464611"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://uppsala.academia.edu/ChristerSundstr%C3%B6m">Christer Sundström</a></span></div><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/NorafizaZainuddin">Norafiza Zainuddin</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-16464611'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-16464611').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_16464611 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="16464611"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 16464611, container: ".js-paper-rank-work_16464611", }); });</script></li><li class="js-percentile-work_16464611 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 16464611; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_16464611"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_16464611 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="16464611"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 16464611; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=16464611]").text(description); $(".js-view-count-work_16464611").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_16464611").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="16464611"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">13</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="121665" href="https://www.academia.edu/Documents/in/DNA_methylation">DNA methylation</a>, <script data-card-contents-for-ri="121665" type="text/json">{"id":121665,"name":"DNA methylation","url":"https://www.academia.edu/Documents/in/DNA_methylation?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="121667" href="https://www.academia.edu/Documents/in/CpG_islands">CpG islands</a><script data-card-contents-for-ri="121667" type="text/json">{"id":121667,"name":"CpG islands","url":"https://www.academia.edu/Documents/in/CpG_islands?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=16464611]'), work: {"id":16464611,"title":"Quantitative evaluation of p16INK4a promoter methylation using pyrosequencing in de novo diffuse large B-cell lymphoma","created_at":"2015-10-04T23:50:34.382-07:00","url":"https://www.academia.edu/16464611/Quantitative_evaluation_of_p16INK4a_promoter_methylation_using_pyrosequencing_in_de_novo_diffuse_large_B_cell_lymphoma?f_ri=14109","dom_id":"work_16464611","summary":null,"downloadable_attachments":[{"id":42484729,"asset_id":16464611,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":35662778,"first_name":"Richard","last_name":"Rosenquist","domain_name":"uppsala","page_name":"RichardRosenquist","display_name":"Richard Rosenquist","profile_url":"https://uppsala.academia.edu/RichardRosenquist?f_ri=14109","photo":"/images/s65_no_pic.png"},{"id":35751553,"first_name":"Christer","last_name":"Sundström","domain_name":"uppsala","page_name":"ChristerSundström","display_name":"Christer Sundström","profile_url":"https://uppsala.academia.edu/ChristerSundstr%C3%B6m?f_ri=14109","photo":"/images/s65_no_pic.png"},{"id":36131089,"first_name":"Norafiza","last_name":"Zainuddin","domain_name":"independent","page_name":"NorafizaZainuddin","display_name":"Norafiza Zainuddin","profile_url":"https://independent.academia.edu/NorafizaZainuddin?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false},{"id":121665,"name":"DNA methylation","url":"https://www.academia.edu/Documents/in/DNA_methylation?f_ri=14109","nofollow":false},{"id":121667,"name":"CpG islands","url":"https://www.academia.edu/Documents/in/CpG_islands?f_ri=14109","nofollow":false},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=14109"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=14109"},{"id":372667,"name":"Tumor Suppressor Gene","url":"https://www.academia.edu/Documents/in/Tumor_Suppressor_Gene?f_ri=14109"},{"id":413194,"name":"Analysis of Variance","url":"https://www.academia.edu/Documents/in/Analysis_of_Variance?f_ri=14109"},{"id":489727,"name":"Prognosis","url":"https://www.academia.edu/Documents/in/Prognosis?f_ri=14109"},{"id":541328,"name":"Diffuse Large B-Cell Lymphoma","url":"https://www.academia.edu/Documents/in/Diffuse_Large_B-Cell_Lymphoma?f_ri=14109"},{"id":1222271,"name":"Quantitative Evaluation","url":"https://www.academia.edu/Documents/in/Quantitative_Evaluation?f_ri=14109"},{"id":1794847,"name":"Progression Free Survival","url":"https://www.academia.edu/Documents/in/Progression_Free_Survival?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_20649225" data-work_id="20649225" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/20649225/Processed_meats_and_risk_of_childhood_leukemia_California_USA_">Processed meats and risk of childhood leukemia (California, USA)</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/20649225" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="2ed364cd9c9d279a412da5497ccb882a" rel="nofollow" data-download="{"attachment_id":41936739,"asset_id":20649225,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/41936739/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="5218433" href="https://dtc-wsuv.academia.edu/DuncanThomas">Duncan Thomas</a><script data-card-contents-for-user="5218433" type="text/json">{"id":5218433,"first_name":"Duncan","last_name":"Thomas","domain_name":"dtc-wsuv","page_name":"DuncanThomas","display_name":"Duncan Thomas","profile_url":"https://dtc-wsuv.academia.edu/DuncanThomas?f_ri=14109","photo":"https://0.academia-photos.com/5218433/2298170/2683042/s65_duncan.thomas.jpg"}</script></span></span></li><li class="js-paper-rank-work_20649225 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="20649225"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 20649225, container: ".js-paper-rank-work_20649225", }); });</script></li><li class="js-percentile-work_20649225 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 20649225; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_20649225"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_20649225 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="20649225"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 20649225; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=20649225]").text(description); $(".js-view-count-work_20649225").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_20649225").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="20649225"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">21</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="24631" href="https://www.academia.edu/Documents/in/Fathers">Fathers</a>, <script data-card-contents-for-ri="24631" type="text/json">{"id":24631,"name":"Fathers","url":"https://www.academia.edu/Documents/in/Fathers?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="39799" href="https://www.academia.edu/Documents/in/Los_Angeles">Los Angeles</a>, <script data-card-contents-for-ri="39799" type="text/json">{"id":39799,"name":"Los Angeles","url":"https://www.academia.edu/Documents/in/Los_Angeles?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="64933" href="https://www.academia.edu/Documents/in/Child">Child</a><script data-card-contents-for-ri="64933" type="text/json">{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=20649225]'), work: {"id":20649225,"title":"Processed meats and risk of childhood leukemia (California, USA)","created_at":"2016-01-23T10:45:31.810-08:00","url":"https://www.academia.edu/20649225/Processed_meats_and_risk_of_childhood_leukemia_California_USA_?f_ri=14109","dom_id":"work_20649225","summary":null,"downloadable_attachments":[{"id":41936739,"asset_id":20649225,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":5218433,"first_name":"Duncan","last_name":"Thomas","domain_name":"dtc-wsuv","page_name":"DuncanThomas","display_name":"Duncan Thomas","profile_url":"https://dtc-wsuv.academia.edu/DuncanThomas?f_ri=14109","photo":"https://0.academia-photos.com/5218433/2298170/2683042/s65_duncan.thomas.jpg"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":24631,"name":"Fathers","url":"https://www.academia.edu/Documents/in/Fathers?f_ri=14109","nofollow":false},{"id":39799,"name":"Los Angeles","url":"https://www.academia.edu/Documents/in/Los_Angeles?f_ri=14109","nofollow":false},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=14109","nofollow":false},{"id":98134,"name":"United States","url":"https://www.academia.edu/Documents/in/United_States?f_ri=14109"},{"id":107106,"name":"Meat","url":"https://www.academia.edu/Documents/in/Meat?f_ri=14109"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=14109"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=14109"},{"id":253560,"name":"Newborn Infant","url":"https://www.academia.edu/Documents/in/Newborn_Infant?f_ri=14109"},{"id":260829,"name":"Cattle","url":"https://www.academia.edu/Documents/in/Cattle?f_ri=14109"},{"id":352757,"name":"Ascorbic Acid","url":"https://www.academia.edu/Documents/in/Ascorbic_Acid?f_ri=14109"},{"id":369093,"name":"Food habits","url":"https://www.academia.edu/Documents/in/Food_habits?f_ri=14109"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=14109"},{"id":419370,"name":"Swine","url":"https://www.academia.edu/Documents/in/Swine?f_ri=14109"},{"id":613764,"name":"Meat products","url":"https://www.academia.edu/Documents/in/Meat_products?f_ri=14109"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=14109"},{"id":732208,"name":"Carbonated Beverages","url":"https://www.academia.edu/Documents/in/Carbonated_Beverages?f_ri=14109"},{"id":910025,"name":"Case Control Study","url":"https://www.academia.edu/Documents/in/Case_Control_Study?f_ri=14109"},{"id":1036777,"name":"Epidemiologic Studies","url":"https://www.academia.edu/Documents/in/Epidemiologic_Studies?f_ri=14109"},{"id":1587858,"name":"Confidence Interval","url":"https://www.academia.edu/Documents/in/Confidence_Interval?f_ri=14109"},{"id":1819399,"name":"Case Control Studies","url":"https://www.academia.edu/Documents/in/Case_Control_Studies?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_19703599" data-work_id="19703599" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/19703599/Screening_of_JAK2_V617F_mutation_in_multiple_myeloma">Screening of JAK2 V617F mutation in multiple myeloma</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/19703599" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="55fd35e55b97de7cdbfaa230f490a23a" rel="nofollow" data-download="{"attachment_id":42048156,"asset_id":19703599,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42048156/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="369169" href="https://unicatt.academia.edu/GiuseppeLeone">Giuseppe Leone</a><script data-card-contents-for-user="369169" type="text/json">{"id":369169,"first_name":"Giuseppe","last_name":"Leone","domain_name":"unicatt","page_name":"GiuseppeLeone","display_name":"Giuseppe Leone","profile_url":"https://unicatt.academia.edu/GiuseppeLeone?f_ri=14109","photo":"https://0.academia-photos.com/369169/2963374/3473970/s65_giuseppe.leone.jpg"}</script></span></span></li><li class="js-paper-rank-work_19703599 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="19703599"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 19703599, container: ".js-paper-rank-work_19703599", }); });</script></li><li class="js-percentile-work_19703599 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 19703599; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_19703599"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_19703599 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="19703599"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 19703599; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=19703599]").text(description); $(".js-view-count-work_19703599").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_19703599").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="19703599"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">4</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="73153" href="https://www.academia.edu/Documents/in/Genetic_Testing">Genetic Testing</a>, <script data-card-contents-for-ri="73153" type="text/json">{"id":73153,"name":"Genetic Testing","url":"https://www.academia.edu/Documents/in/Genetic_Testing?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="111110" href="https://www.academia.edu/Documents/in/Multiple_Myeloma">Multiple Myeloma</a>, <script data-card-contents-for-ri="111110" type="text/json">{"id":111110,"name":"Multiple Myeloma","url":"https://www.academia.edu/Documents/in/Multiple_Myeloma?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a><script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=19703599]'), work: {"id":19703599,"title":"Screening of JAK2 V617F mutation in multiple myeloma","created_at":"2015-12-17T02:58:38.413-08:00","url":"https://www.academia.edu/19703599/Screening_of_JAK2_V617F_mutation_in_multiple_myeloma?f_ri=14109","dom_id":"work_19703599","summary":null,"downloadable_attachments":[{"id":42048156,"asset_id":19703599,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":369169,"first_name":"Giuseppe","last_name":"Leone","domain_name":"unicatt","page_name":"GiuseppeLeone","display_name":"Giuseppe Leone","profile_url":"https://unicatt.academia.edu/GiuseppeLeone?f_ri=14109","photo":"https://0.academia-photos.com/369169/2963374/3473970/s65_giuseppe.leone.jpg"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":73153,"name":"Genetic Testing","url":"https://www.academia.edu/Documents/in/Genetic_Testing?f_ri=14109","nofollow":false},{"id":111110,"name":"Multiple Myeloma","url":"https://www.academia.edu/Documents/in/Multiple_Myeloma?f_ri=14109","nofollow":false},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_78533445" data-work_id="78533445" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/78533445/The_leukemic_B_cell_population_of_patients_with_monoclonal_lymphocytosis_of_undetermined_significance_MLUS_are_functionally_distinct_from_the_chronic_lymphocytic_leukemia_CLL_derived_cell_population">The leukemic B-cell population of patients with monoclonal lymphocytosis of undetermined significance (MLUS) are functionally distinct from the chronic lymphocytic leukemia (CLL) derived cell population</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/78533445" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="f26233b7b7f03e4e4da6f87968a2d177" rel="nofollow" data-download="{"attachment_id":85548399,"asset_id":78533445,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/85548399/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="37893490" href="https://independent.academia.edu/Pierre%C3%85man">Pierre Åman</a><script data-card-contents-for-user="37893490" type="text/json">{"id":37893490,"first_name":"Pierre","last_name":"Åman","domain_name":"independent","page_name":"PierreÅman","display_name":"Pierre Åman","profile_url":"https://independent.academia.edu/Pierre%C3%85man?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_78533445 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="78533445"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 78533445, container: ".js-paper-rank-work_78533445", }); });</script></li><li class="js-percentile-work_78533445 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 78533445; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_78533445"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_78533445 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="78533445"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 78533445; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=78533445]").text(description); $(".js-view-count-work_78533445").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_78533445").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="78533445"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">8</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="7710" href="https://www.academia.edu/Documents/in/Biology">Biology</a>, <script data-card-contents-for-ri="7710" type="text/json">{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a><script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=78533445]'), work: {"id":78533445,"title":"The leukemic B-cell population of patients with monoclonal lymphocytosis of undetermined significance (MLUS) are functionally distinct from the chronic lymphocytic leukemia (CLL) derived cell population","created_at":"2022-05-05T10:12:00.335-07:00","url":"https://www.academia.edu/78533445/The_leukemic_B_cell_population_of_patients_with_monoclonal_lymphocytosis_of_undetermined_significance_MLUS_are_functionally_distinct_from_the_chronic_lymphocytic_leukemia_CLL_derived_cell_population?f_ri=14109","dom_id":"work_78533445","summary":null,"downloadable_attachments":[{"id":85548399,"asset_id":78533445,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":37893490,"first_name":"Pierre","last_name":"Åman","domain_name":"independent","page_name":"PierreÅman","display_name":"Pierre Åman","profile_url":"https://independent.academia.edu/Pierre%C3%85man?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=14109","nofollow":false},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109","nofollow":false},{"id":678853,"name":"B Lymphocytes","url":"https://www.academia.edu/Documents/in/B_Lymphocytes?f_ri=14109"},{"id":859027,"name":"Adhesion molecules","url":"https://www.academia.edu/Documents/in/Adhesion_molecules?f_ri=14109"},{"id":1345809,"name":"Lymphocytosis","url":"https://www.academia.edu/Documents/in/Lymphocytosis?f_ri=14109"},{"id":2524494,"name":"Cell Aggregation","url":"https://www.academia.edu/Documents/in/Cell_Aggregation?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_69433927" data-work_id="69433927" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/69433927/Malignant_tumors_of_infancy_and_childhood">Malignant tumors of infancy and childhood</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/69433927" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="aead52595fac908f4d554ccaedbcd58d" rel="nofollow" data-download="{"attachment_id":79534245,"asset_id":69433927,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/79534245/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="139695833" href="https://independent.academia.edu/amalbill">amal bill</a><script data-card-contents-for-user="139695833" type="text/json">{"id":139695833,"first_name":"amal","last_name":"bill","domain_name":"independent","page_name":"amalbill","display_name":"amal bill","profile_url":"https://independent.academia.edu/amalbill?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_69433927 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="69433927"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 69433927, container: ".js-paper-rank-work_69433927", }); });</script></li><li class="js-percentile-work_69433927 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 69433927; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_69433927"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_69433927 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="69433927"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 69433927; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=69433927]").text(description); $(".js-view-count-work_69433927").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_69433927").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="69433927"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">11</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="588" href="https://www.academia.edu/Documents/in/Nursing">Nursing</a>, <script data-card-contents-for-ri="588" type="text/json">{"id":588,"name":"Nursing","url":"https://www.academia.edu/Documents/in/Nursing?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="64933" href="https://www.academia.edu/Documents/in/Child">Child</a><script data-card-contents-for-ri="64933" type="text/json">{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=69433927]'), work: {"id":69433927,"title":"Malignant tumors of infancy and childhood","created_at":"2022-01-25T09:26:29.730-08:00","url":"https://www.academia.edu/69433927/Malignant_tumors_of_infancy_and_childhood?f_ri=14109","dom_id":"work_69433927","summary":null,"downloadable_attachments":[{"id":79534245,"asset_id":69433927,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":139695833,"first_name":"amal","last_name":"bill","domain_name":"independent","page_name":"amalbill","display_name":"amal bill","profile_url":"https://independent.academia.edu/amalbill?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":588,"name":"Nursing","url":"https://www.academia.edu/Documents/in/Nursing?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=14109","nofollow":false},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=14109","nofollow":false},{"id":118793,"name":"Sarcoma","url":"https://www.academia.edu/Documents/in/Sarcoma?f_ri=14109"},{"id":256805,"name":"Neuroblastoma","url":"https://www.academia.edu/Documents/in/Neuroblastoma?f_ri=14109"},{"id":295680,"name":"Retinoblastoma","url":"https://www.academia.edu/Documents/in/Retinoblastoma?f_ri=14109"},{"id":371491,"name":"Carcinoma","url":"https://www.academia.edu/Documents/in/Carcinoma?f_ri=14109"},{"id":883404,"name":"Teratoma","url":"https://www.academia.edu/Documents/in/Teratoma?f_ri=14109"},{"id":1350756,"name":"Hodgkin disease","url":"https://www.academia.edu/Documents/in/Hodgkin_disease?f_ri=14109"},{"id":2683401,"name":"Wilms tumor","url":"https://www.academia.edu/Documents/in/Wilms_tumor-1?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_2766574" data-work_id="2766574" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/2766574/The_Core_Beliefs_Inventory_a_brief_measure_of_disruption_in_the_assumptive_world">The Core Beliefs Inventory: a brief measure of disruption in the assumptive world</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Stressful events that disrupt the assumptive world can force people to make cognitive changes to accommodate these highly stressful experiences. As fundamental assumptions are reestablished, many people report changes and experiences that... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_2766574" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Stressful events that disrupt the assumptive world can force people to make cognitive changes to accommodate these highly stressful experiences. As fundamental assumptions are reestablished, many people report changes and experiences that reflect posttraumatic growth (PTG). The present research describes the development of the Core Beliefs Inventory (CBI), a brief measure of disruption of the assumptive world developed for use in applied research and clinical settings. Three studies, two using college samples (Study 1, n=181 and Study 2, n=297 time 1; 85 time 2) and the third using leukemia patients (Study 3, n=70 time 1; 43 time 2), assessed the utility of the CBI to predict PTG in both cross-sectional and longitudinal designs. Relationships between the CBI and measures of self-reported PTG and well-being indicate that the CBI has construct validity, acceptable test-retest reliability, and very good internal consistency. The CBI may be a useful tool in investigating predictions about the effects of stressful experiences on an individual's assumptive world, PTG, and successful adaptation.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/2766574" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="431a00e7e71bc6a50df30967242a8537" rel="nofollow" data-download="{"attachment_id":50548578,"asset_id":2766574,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/50548578/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="3397710" href="https://uncc.academia.edu/TanyaVishnevsky">Tanya Vishnevsky</a><script data-card-contents-for-user="3397710" type="text/json">{"id":3397710,"first_name":"Tanya","last_name":"Vishnevsky","domain_name":"uncc","page_name":"TanyaVishnevsky","display_name":"Tanya Vishnevsky","profile_url":"https://uncc.academia.edu/TanyaVishnevsky?f_ri=14109","photo":"https://0.academia-photos.com/3397710/1149023/1439152/s65_tanya.vishnevsky.jpg"}</script></span></span></li><li class="js-paper-rank-work_2766574 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="2766574"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 2766574, container: ".js-paper-rank-work_2766574", }); });</script></li><li class="js-percentile-work_2766574 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 2766574; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_2766574"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_2766574 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="2766574"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 2766574; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=2766574]").text(description); $(".js-view-count-work_2766574").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_2766574").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="2766574"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">15</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="221" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="9697" href="https://www.academia.edu/Documents/in/Applied_Research">Applied Research</a>, <script data-card-contents-for-ri="9697" type="text/json">{"id":9697,"name":"Applied Research","url":"https://www.academia.edu/Documents/in/Applied_Research?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a><script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=2766574]'), work: {"id":2766574,"title":"The Core Beliefs Inventory: a brief measure of disruption in the assumptive world","created_at":"2013-03-01T02:22:31.931-08:00","url":"https://www.academia.edu/2766574/The_Core_Beliefs_Inventory_a_brief_measure_of_disruption_in_the_assumptive_world?f_ri=14109","dom_id":"work_2766574","summary":"Stressful events that disrupt the assumptive world can force people to make cognitive changes to accommodate these highly stressful experiences. As fundamental assumptions are reestablished, many people report changes and experiences that reflect posttraumatic growth (PTG). The present research describes the development of the Core Beliefs Inventory (CBI), a brief measure of disruption of the assumptive world developed for use in applied research and clinical settings. Three studies, two using college samples (Study 1, n=181 and Study 2, n=297 time 1; 85 time 2) and the third using leukemia patients (Study 3, n=70 time 1; 43 time 2), assessed the utility of the CBI to predict PTG in both cross-sectional and longitudinal designs. Relationships between the CBI and measures of self-reported PTG and well-being indicate that the CBI has construct validity, acceptable test-retest reliability, and very good internal consistency. The CBI may be a useful tool in investigating predictions about the effects of stressful experiences on an individual's assumptive world, PTG, and successful adaptation.","downloadable_attachments":[{"id":50548578,"asset_id":2766574,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":3397710,"first_name":"Tanya","last_name":"Vishnevsky","domain_name":"uncc","page_name":"TanyaVishnevsky","display_name":"Tanya Vishnevsky","profile_url":"https://uncc.academia.edu/TanyaVishnevsky?f_ri=14109","photo":"https://0.academia-photos.com/3397710/1149023/1439152/s65_tanya.vishnevsky.jpg"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=14109","nofollow":false},{"id":9697,"name":"Applied Research","url":"https://www.academia.edu/Documents/in/Applied_Research?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false},{"id":50490,"name":"Stress and Anxiety","url":"https://www.academia.edu/Documents/in/Stress_and_Anxiety?f_ri=14109"},{"id":73149,"name":"Business and Management","url":"https://www.academia.edu/Documents/in/Business_and_Management?f_ri=14109"},{"id":73785,"name":"Personality Assessment Inventory","url":"https://www.academia.edu/Documents/in/Personality_Assessment_Inventory?f_ri=14109"},{"id":104434,"name":"Construct Validity","url":"https://www.academia.edu/Documents/in/Construct_Validity?f_ri=14109"},{"id":123230,"name":"Regression Analysis","url":"https://www.academia.edu/Documents/in/Regression_Analysis?f_ri=14109"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=14109"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=14109"},{"id":314162,"name":"Psychological Tests","url":"https://www.academia.edu/Documents/in/Psychological_Tests?f_ri=14109"},{"id":404000,"name":"Cross Section","url":"https://www.academia.edu/Documents/in/Cross_Section?f_ri=14109"},{"id":549280,"name":"Reproducibility of Results","url":"https://www.academia.edu/Documents/in/Reproducibility_of_Results?f_ri=14109"},{"id":1414499,"name":"Life Change Events","url":"https://www.academia.edu/Documents/in/Life_Change_Events?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_13484498" data-work_id="13484498" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13484498/Vaccination_and_the_risk_of_childhood_acute_leukaemia_the_ESCALE_study_SFCEy_">Vaccination and the risk of childhood acute leukaemia: the ESCALE study (SFCEy)</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Background In 2002, a poster alerted the French health authorities to the possibility that the risk of childhood leukaemia might be increased by hepatitis B vaccination. Elucidating the role of vaccination in the aetiology of childhood... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_13484498" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Background In 2002, a poster alerted the French health authorities to the possibility that the risk of childhood leukaemia might be increased by hepatitis B vaccination. Elucidating the role of vaccination in the aetiology of childhood acute leukaemia (AL) was therefore included in the objectives of an ongoing national study. Methods The ESCALE study was a French national population-based case-control</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13484498" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="25bc0fb02382d01df774df7183e44365" rel="nofollow" data-download="{"attachment_id":38058281,"asset_id":13484498,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/38058281/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32696908" href="https://univ-paris-diderot.academia.edu/Andr%C3%89Baruchel">AndrÉ Baruchel</a><script data-card-contents-for-user="32696908" type="text/json">{"id":32696908,"first_name":"AndrÉ","last_name":"Baruchel","domain_name":"univ-paris-diderot","page_name":"AndrÉBaruchel","display_name":"AndrÉ Baruchel","profile_url":"https://univ-paris-diderot.academia.edu/Andr%C3%89Baruchel?f_ri=14109","photo":"https://0.academia-photos.com/32696908/18291549/18260417/s65_andr_.baruchel.jpg"}</script></span></span></li><li class="js-paper-rank-work_13484498 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="13484498"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 13484498, container: ".js-paper-rank-work_13484498", }); });</script></li><li class="js-percentile-work_13484498 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 13484498; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_13484498"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_13484498 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="13484498"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 13484498; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=13484498]").text(description); $(".js-view-count-work_13484498").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_13484498").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="13484498"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">18</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="892" href="https://www.academia.edu/Documents/in/Statistics">Statistics</a>, <script data-card-contents-for-ri="892" type="text/json">{"id":892,"name":"Statistics","url":"https://www.academia.edu/Documents/in/Statistics?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="1085" href="https://www.academia.edu/Documents/in/Epidemiology">Epidemiology</a>, <script data-card-contents-for-ri="1085" type="text/json">{"id":1085,"name":"Epidemiology","url":"https://www.academia.edu/Documents/in/Epidemiology?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="16664" href="https://www.academia.edu/Documents/in/Risk_assessment">Risk assessment</a><script data-card-contents-for-ri="16664" type="text/json">{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=13484498]'), work: {"id":13484498,"title":"Vaccination and the risk of childhood acute leukaemia: the ESCALE study (SFCEy)","created_at":"2015-07-01T04:19:01.841-07:00","url":"https://www.academia.edu/13484498/Vaccination_and_the_risk_of_childhood_acute_leukaemia_the_ESCALE_study_SFCEy_?f_ri=14109","dom_id":"work_13484498","summary":"Background In 2002, a poster alerted the French health authorities to the possibility that the risk of childhood leukaemia might be increased by hepatitis B vaccination. Elucidating the role of vaccination in the aetiology of childhood acute leukaemia (AL) was therefore included in the objectives of an ongoing national study. Methods The ESCALE study was a French national population-based case-control","downloadable_attachments":[{"id":38058281,"asset_id":13484498,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32696908,"first_name":"AndrÉ","last_name":"Baruchel","domain_name":"univ-paris-diderot","page_name":"AndrÉBaruchel","display_name":"AndrÉ Baruchel","profile_url":"https://univ-paris-diderot.academia.edu/Andr%C3%89Baruchel?f_ri=14109","photo":"https://0.academia-photos.com/32696908/18291549/18260417/s65_andr_.baruchel.jpg"}],"research_interests":[{"id":892,"name":"Statistics","url":"https://www.academia.edu/Documents/in/Statistics?f_ri=14109","nofollow":false},{"id":1085,"name":"Epidemiology","url":"https://www.academia.edu/Documents/in/Epidemiology?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=14109","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109"},{"id":27336,"name":"France","url":"https://www.academia.edu/Documents/in/France?f_ri=14109"},{"id":59057,"name":"Acute Myeloid Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia?f_ri=14109"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=14109"},{"id":125175,"name":"Acute Lymphoblastic Leukaemia","url":"https://www.academia.edu/Documents/in/Acute_Lymphoblastic_Leukaemia?f_ri=14109"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=14109"},{"id":179934,"name":"Vaccination","url":"https://www.academia.edu/Documents/in/Vaccination?f_ri=14109"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=14109"},{"id":622589,"name":"Risk Assessment","url":"https://www.academia.edu/Documents/in/Risk_Assessment-2?f_ri=14109"},{"id":910025,"name":"Case Control Study","url":"https://www.academia.edu/Documents/in/Case_Control_Study?f_ri=14109"},{"id":1334751,"name":"Hepatitis B Vaccine","url":"https://www.academia.edu/Documents/in/Hepatitis_B_Vaccine?f_ri=14109"},{"id":1529194,"name":"Hepatitis B Vaccines","url":"https://www.academia.edu/Documents/in/Hepatitis_B_Vaccines?f_ri=14109"},{"id":1819399,"name":"Case Control Studies","url":"https://www.academia.edu/Documents/in/Case_Control_Studies?f_ri=14109"},{"id":2153358,"name":"Brain Tumour","url":"https://www.academia.edu/Documents/in/Brain_Tumour?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_25328281" data-work_id="25328281" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/25328281/Sorafenib_for_refractory_FMS_like_tyrosine_kinase_receptor_3_FLT3_ITD_acute_myeloid_leukemia_after_allogenic_stem_cell_transplantation">Sorafenib for refractory FMS-like tyrosine kinase receptor-3 (FLT3/ITD+) acute myeloid leukemia after allogenic stem cell transplantation</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/25328281" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="602ce1cae9b491417af63ff3f6f948cc" rel="nofollow" data-download="{"attachment_id":45626755,"asset_id":25328281,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45626755/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="31895669" href="https://independent.academia.edu/GiusepeLeone">Giuseppe G M Leone</a><script data-card-contents-for-user="31895669" type="text/json">{"id":31895669,"first_name":"Giuseppe","last_name":"Leone","domain_name":"independent","page_name":"GiusepeLeone","display_name":"Giuseppe G M Leone","profile_url":"https://independent.academia.edu/GiusepeLeone?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_25328281 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="25328281"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 25328281, container: ".js-paper-rank-work_25328281", }); });</script></li><li class="js-percentile-work_25328281 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 25328281; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_25328281"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_25328281 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="25328281"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 25328281; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=25328281]").text(description); $(".js-view-count-work_25328281").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_25328281").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="25328281"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">11</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="37864" href="https://www.academia.edu/Documents/in/Stem_Cell_Transplantation">Stem Cell Transplantation</a>, <script data-card-contents-for-ri="37864" type="text/json">{"id":37864,"name":"Stem Cell Transplantation","url":"https://www.academia.edu/Documents/in/Stem_Cell_Transplantation?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="59057" href="https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia">Acute Myeloid Leukemia</a>, <script data-card-contents-for-ri="59057" type="text/json">{"id":59057,"name":"Acute Myeloid Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="74780" href="https://www.academia.edu/Documents/in/Mutation">Mutation</a><script data-card-contents-for-ri="74780" type="text/json">{"id":74780,"name":"Mutation","url":"https://www.academia.edu/Documents/in/Mutation?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=25328281]'), work: {"id":25328281,"title":"Sorafenib for refractory FMS-like tyrosine kinase receptor-3 (FLT3/ITD+) acute myeloid leukemia after allogenic stem cell transplantation","created_at":"2016-05-14T12:26:20.006-07:00","url":"https://www.academia.edu/25328281/Sorafenib_for_refractory_FMS_like_tyrosine_kinase_receptor_3_FLT3_ITD_acute_myeloid_leukemia_after_allogenic_stem_cell_transplantation?f_ri=14109","dom_id":"work_25328281","summary":null,"downloadable_attachments":[{"id":45626755,"asset_id":25328281,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":31895669,"first_name":"Giuseppe","last_name":"Leone","domain_name":"independent","page_name":"GiusepeLeone","display_name":"Giuseppe G M Leone","profile_url":"https://independent.academia.edu/GiusepeLeone?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":37864,"name":"Stem Cell Transplantation","url":"https://www.academia.edu/Documents/in/Stem_Cell_Transplantation?f_ri=14109","nofollow":false},{"id":59057,"name":"Acute Myeloid Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia?f_ri=14109","nofollow":false},{"id":74780,"name":"Mutation","url":"https://www.academia.edu/Documents/in/Mutation?f_ri=14109","nofollow":false},{"id":87027,"name":"Tyrosine Kinase Receptor","url":"https://www.academia.edu/Documents/in/Tyrosine_Kinase_Receptor?f_ri=14109"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=14109"},{"id":229285,"name":"Skin Diseases","url":"https://www.academia.edu/Documents/in/Skin_Diseases?f_ri=14109"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109"},{"id":490260,"name":"Pyridines","url":"https://www.academia.edu/Documents/in/Pyridines?f_ri=14109"},{"id":1212103,"name":"Antineoplastic Agents","url":"https://www.academia.edu/Documents/in/Antineoplastic_Agents?f_ri=14109"},{"id":2430299,"name":"Gastrointestinal Diseases","url":"https://www.academia.edu/Documents/in/Gastrointestinal_Diseases?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_4955807" data-work_id="4955807" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/4955807/Outcome_of_Cord_Blood_Transplantation_from_Related_and_Unrelated_Donors">Outcome of Cord-Blood Transplantation from Related and Unrelated Donors</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Cord-blood banks have increased the use of cord-blood transplantation in patients with hematologic disorders. We have established a registry containing information on the outcome of cord-blood transplantation. We sent questionnaires to 45... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_4955807" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Cord-blood banks have increased the use of cord-blood transplantation in patients with hematologic disorders. We have established a registry containing information on the outcome of cord-blood transplantation. We sent questionnaires to 45 transplantation centers for information on patients receiving cord-blood transplants from 1988 to 1996. Reports on 143 transplantations, performed at 45 centers, were studied, and the responses were analyzed separately according to whether the donor was related or unrelated to the recipient. Among 78 recipients of cord blood from related donors, the Kaplan-Meier estimate of survival at one year was 63 percent. Younger age, lower weight, transplants from HLA-identical donors, and cytomegalovirus-negative serologic results in the recipient were favorable prognostic factors. Graft-versus-host-disease of at least grade II occurred at estimated rates of 9 percent in 60 recipients of HLA-matched cord blood and 50 percent in 18 recipients of HLA-mismatched cord blood. Neutrophil engraftment was associated with an age of less than six years (P = 0.02) and a weight of less than 20 kg (P = 0.02), and it occurred in 85 percent of patients receiving 37 million or more nucleated cells per kilogram of body weight. Among 65 patients who received cord blood from unrelated donors, the Kaplan-Meier estimate of survival at one year was 29 percent. Cytomegalovirus-negative serologic status in these recipients was associated with improved survival (P = 0.03) and was the most important predictor of graft-versus-host disease (P = 0.04). Neutrophil recovery occurred in 94 percent of the patients who received 37 million or more nucleated cells per kilogram from unrelated donors. Cord blood is a feasible alternative source of hematopoietic stem cells for pediatric and some adult patients with major hematologic disorders, particularly if the donor and the recipient are related.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/4955807" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="8e097adbfb9b20839c9bc42702f0a552" rel="nofollow" data-download="{"attachment_id":49514651,"asset_id":4955807,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/49514651/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="6528734" href="https://unini.academia.edu/juanortega">juan ortega</a><script data-card-contents-for-user="6528734" type="text/json">{"id":6528734,"first_name":"juan","last_name":"ortega","domain_name":"unini","page_name":"juanortega","display_name":"juan ortega","profile_url":"https://unini.academia.edu/juanortega?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_4955807 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="4955807"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 4955807, container: ".js-paper-rank-work_4955807", }); });</script></li><li class="js-percentile-work_4955807 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 4955807; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_4955807"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_4955807 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="4955807"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 4955807; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=4955807]").text(description); $(".js-view-count-work_4955807").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_4955807").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="4955807"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">13</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="10610" href="https://www.academia.edu/Documents/in/Survival_Analysis">Survival Analysis</a>, <script data-card-contents-for-ri="10610" type="text/json">{"id":10610,"name":"Survival Analysis","url":"https://www.academia.edu/Documents/in/Survival_Analysis?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="12426" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a>, <script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a><script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=4955807]'), work: {"id":4955807,"title":"Outcome of Cord-Blood Transplantation from Related and Unrelated Donors","created_at":"2013-11-01T01:01:30.445-07:00","url":"https://www.academia.edu/4955807/Outcome_of_Cord_Blood_Transplantation_from_Related_and_Unrelated_Donors?f_ri=14109","dom_id":"work_4955807","summary":"Cord-blood banks have increased the use of cord-blood transplantation in patients with hematologic disorders. We have established a registry containing information on the outcome of cord-blood transplantation. We sent questionnaires to 45 transplantation centers for information on patients receiving cord-blood transplants from 1988 to 1996. Reports on 143 transplantations, performed at 45 centers, were studied, and the responses were analyzed separately according to whether the donor was related or unrelated to the recipient. Among 78 recipients of cord blood from related donors, the Kaplan-Meier estimate of survival at one year was 63 percent. Younger age, lower weight, transplants from HLA-identical donors, and cytomegalovirus-negative serologic results in the recipient were favorable prognostic factors. Graft-versus-host-disease of at least grade II occurred at estimated rates of 9 percent in 60 recipients of HLA-matched cord blood and 50 percent in 18 recipients of HLA-mismatched cord blood. Neutrophil engraftment was associated with an age of less than six years (P = 0.02) and a weight of less than 20 kg (P = 0.02), and it occurred in 85 percent of patients receiving 37 million or more nucleated cells per kilogram of body weight. Among 65 patients who received cord blood from unrelated donors, the Kaplan-Meier estimate of survival at one year was 29 percent. Cytomegalovirus-negative serologic status in these recipients was associated with improved survival (P = 0.03) and was the most important predictor of graft-versus-host disease (P = 0.04). Neutrophil recovery occurred in 94 percent of the patients who received 37 million or more nucleated cells per kilogram from unrelated donors. Cord blood is a feasible alternative source of hematopoietic stem cells for pediatric and some adult patients with major hematologic disorders, particularly if the donor and the recipient are related.","downloadable_attachments":[{"id":49514651,"asset_id":4955807,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":6528734,"first_name":"juan","last_name":"ortega","domain_name":"unini","page_name":"juanortega","display_name":"juan ortega","profile_url":"https://unini.academia.edu/juanortega?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":10610,"name":"Survival Analysis","url":"https://www.academia.edu/Documents/in/Survival_Analysis?f_ri=14109","nofollow":false},{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=14109"},{"id":88839,"name":"Cord Blood","url":"https://www.academia.edu/Documents/in/Cord_Blood?f_ri=14109"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=14109"},{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies?f_ri=14109"},{"id":153168,"name":"Data Collection","url":"https://www.academia.edu/Documents/in/Data_Collection?f_ri=14109"},{"id":234187,"name":"Recurrence","url":"https://www.academia.edu/Documents/in/Recurrence?f_ri=14109"},{"id":435727,"name":"Major histocompatibility complex","url":"https://www.academia.edu/Documents/in/Major_histocompatibility_complex?f_ri=14109"},{"id":679066,"name":"Blood Donors","url":"https://www.academia.edu/Documents/in/Blood_Donors?f_ri=14109"},{"id":1161066,"name":"New England Journalof Medicine","url":"https://www.academia.edu/Documents/in/New_England_Journalof_Medicine?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_68083217" data-work_id="68083217" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/68083217/Evidence_based_care_for_the_neutropenic_patient_with_leukemia">Evidence-based care for the neutropenic patient with leukemia</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/68083217" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="7b04b9f59102b5e5496087146b1a0838" rel="nofollow" data-download="{"attachment_id":78686915,"asset_id":68083217,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/78686915/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="56078479" href="https://independent.academia.edu/BrendaShelton3">Brenda Shelton</a><script data-card-contents-for-user="56078479" type="text/json">{"id":56078479,"first_name":"Brenda","last_name":"Shelton","domain_name":"independent","page_name":"BrendaShelton3","display_name":"Brenda Shelton","profile_url":"https://independent.academia.edu/BrendaShelton3?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_68083217 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="68083217"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 68083217, container: ".js-paper-rank-work_68083217", }); });</script></li><li class="js-percentile-work_68083217 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 68083217; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_68083217"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_68083217 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="68083217"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 68083217; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=68083217]").text(description); $(".js-view-count-work_68083217").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_68083217").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="68083217"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">17</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="588" href="https://www.academia.edu/Documents/in/Nursing">Nursing</a>, <script data-card-contents-for-ri="588" type="text/json">{"id":588,"name":"Nursing","url":"https://www.academia.edu/Documents/in/Nursing?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="3645" href="https://www.academia.edu/Documents/in/Evidence_Based_Medicine">Evidence Based Medicine</a>, <script data-card-contents-for-ri="3645" type="text/json">{"id":3645,"name":"Evidence Based Medicine","url":"https://www.academia.edu/Documents/in/Evidence_Based_Medicine?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="8942" href="https://www.academia.edu/Documents/in/Treatment">Treatment</a>, <script data-card-contents-for-ri="8942" type="text/json">{"id":8942,"name":"Treatment","url":"https://www.academia.edu/Documents/in/Treatment?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a><script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=68083217]'), work: {"id":68083217,"title":"Evidence-based care for the neutropenic patient with leukemia","created_at":"2022-01-14T02:52:17.564-08:00","url":"https://www.academia.edu/68083217/Evidence_based_care_for_the_neutropenic_patient_with_leukemia?f_ri=14109","dom_id":"work_68083217","summary":null,"downloadable_attachments":[{"id":78686915,"asset_id":68083217,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":56078479,"first_name":"Brenda","last_name":"Shelton","domain_name":"independent","page_name":"BrendaShelton3","display_name":"Brenda Shelton","profile_url":"https://independent.academia.edu/BrendaShelton3?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":588,"name":"Nursing","url":"https://www.academia.edu/Documents/in/Nursing?f_ri=14109","nofollow":false},{"id":3645,"name":"Evidence Based Medicine","url":"https://www.academia.edu/Documents/in/Evidence_Based_Medicine?f_ri=14109","nofollow":false},{"id":8942,"name":"Treatment","url":"https://www.academia.edu/Documents/in/Treatment?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=14109"},{"id":27240,"name":"Prevention","url":"https://www.academia.edu/Documents/in/Prevention?f_ri=14109"},{"id":67405,"name":"Toxicity","url":"https://www.academia.edu/Documents/in/Toxicity?f_ri=14109"},{"id":98134,"name":"United States","url":"https://www.academia.edu/Documents/in/United_States?f_ri=14109"},{"id":101565,"name":"Oncology Nursing","url":"https://www.academia.edu/Documents/in/Oncology_Nursing?f_ri=14109"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=14109"},{"id":387144,"name":"Fever","url":"https://www.academia.edu/Documents/in/Fever?f_ri=14109"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=14109"},{"id":704648,"name":"Clinical Competence","url":"https://www.academia.edu/Documents/in/Clinical_Competence?f_ri=14109"},{"id":784431,"name":"Nursing Assessment","url":"https://www.academia.edu/Documents/in/Nursing_Assessment?f_ri=14109"},{"id":1212103,"name":"Antineoplastic Agents","url":"https://www.academia.edu/Documents/in/Antineoplastic_Agents?f_ri=14109"},{"id":1347023,"name":"Clinical Nursing Research","url":"https://www.academia.edu/Documents/in/Clinical_Nursing_Research?f_ri=14109"},{"id":2969290,"name":"neutropenia","url":"https://www.academia.edu/Documents/in/neutropenia?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_25438209" data-work_id="25438209" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/25438209/Proportionate_mortality_ratio_analysis_of_automobile_mechanics_and_gasoline_service_station_workers_in_New_Hampshire">Proportionate mortality ratio analysis of automobile mechanics and gasoline service station workers in New Hampshire</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/25438209" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="d34e52da0c138ec11aa4ececdc0745e0" rel="nofollow" data-download="{"attachment_id":45755052,"asset_id":25438209,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45755052/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="48804302" href="https://independent.academia.edu/ESchwartz3">E. Schwartz</a><script data-card-contents-for-user="48804302" type="text/json">{"id":48804302,"first_name":"E.","last_name":"Schwartz","domain_name":"independent","page_name":"ESchwartz3","display_name":"E. Schwartz","profile_url":"https://independent.academia.edu/ESchwartz3?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_25438209 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="25438209"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 25438209, container: ".js-paper-rank-work_25438209", }); });</script></li><li class="js-percentile-work_25438209 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 25438209; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_25438209"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_25438209 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="25438209"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 25438209; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=25438209]").text(description); $(".js-view-count-work_25438209").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_25438209").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="25438209"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="5285" href="https://www.academia.edu/Documents/in/Petroleum">Petroleum</a>, <script data-card-contents-for-ri="5285" type="text/json">{"id":5285,"name":"Petroleum","url":"https://www.academia.edu/Documents/in/Petroleum?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="45666" href="https://www.academia.edu/Documents/in/Automobiles">Automobiles</a>, <script data-card-contents-for-ri="45666" type="text/json">{"id":45666,"name":"Automobiles","url":"https://www.academia.edu/Documents/in/Automobiles?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="249462" href="https://www.academia.edu/Documents/in/New_Hampshire">New Hampshire</a><script data-card-contents-for-ri="249462" type="text/json">{"id":249462,"name":"New Hampshire","url":"https://www.academia.edu/Documents/in/New_Hampshire?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=25438209]'), work: {"id":25438209,"title":"Proportionate mortality ratio analysis of automobile mechanics and gasoline service station workers in New Hampshire","created_at":"2016-05-18T14:25:01.612-07:00","url":"https://www.academia.edu/25438209/Proportionate_mortality_ratio_analysis_of_automobile_mechanics_and_gasoline_service_station_workers_in_New_Hampshire?f_ri=14109","dom_id":"work_25438209","summary":null,"downloadable_attachments":[{"id":45755052,"asset_id":25438209,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":48804302,"first_name":"E.","last_name":"Schwartz","domain_name":"independent","page_name":"ESchwartz3","display_name":"E. Schwartz","profile_url":"https://independent.academia.edu/ESchwartz3?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":5285,"name":"Petroleum","url":"https://www.academia.edu/Documents/in/Petroleum?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":45666,"name":"Automobiles","url":"https://www.academia.edu/Documents/in/Automobiles?f_ri=14109","nofollow":false},{"id":249462,"name":"New Hampshire","url":"https://www.academia.edu/Documents/in/New_Hampshire?f_ri=14109","nofollow":false},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=14109"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=14109"},{"id":469018,"name":"Neoplasms","url":"https://www.academia.edu/Documents/in/Neoplasms?f_ri=14109"},{"id":743616,"name":"Gasoline","url":"https://www.academia.edu/Documents/in/Gasoline?f_ri=14109"},{"id":962276,"name":"Occupational Diseases","url":"https://www.academia.edu/Documents/in/Occupational_Diseases?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_75384003" data-work_id="75384003" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/75384003/IGHV_gene_features_and_MYD88_L265P_mutation_separate_the_three_marginal_zone_lymphoma_entities_and_Waldenstr%C3%B6m_macroglobulinemia_lymphoplasmacytic_lymphomas">IGHV gene features and MYD88 L265P mutation separate the three marginal zone lymphoma entities and Waldenström macroglobulinemia/lymphoplasmacytic lymphomas</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/75384003" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="154a148537df9c1aca1d5effdd1ae5d3" rel="nofollow" data-download="{"attachment_id":83174283,"asset_id":75384003,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/83174283/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="89156635" href="https://independent.academia.edu/IsabelleSoubeyran">Isabelle Soubeyran</a><script data-card-contents-for-user="89156635" type="text/json">{"id":89156635,"first_name":"Isabelle","last_name":"Soubeyran","domain_name":"independent","page_name":"IsabelleSoubeyran","display_name":"Isabelle Soubeyran","profile_url":"https://independent.academia.edu/IsabelleSoubeyran?f_ri=14109","photo":"https://0.academia-photos.com/89156635/62905097/51203251/s65_isabelle.soubeyran.png"}</script></span></span></li><li class="js-paper-rank-work_75384003 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="75384003"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 75384003, container: ".js-paper-rank-work_75384003", }); });</script></li><li class="js-percentile-work_75384003 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 75384003; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_75384003"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_75384003 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="75384003"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 75384003; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=75384003]").text(description); $(".js-view-count-work_75384003").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_75384003").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="75384003"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="6599" href="https://www.academia.edu/Documents/in/Flow_Cytometry">Flow Cytometry</a>, <script data-card-contents-for-ri="6599" type="text/json">{"id":6599,"name":"Flow Cytometry","url":"https://www.academia.edu/Documents/in/Flow_Cytometry?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="7710" href="https://www.academia.edu/Documents/in/Biology">Biology</a>, <script data-card-contents-for-ri="7710" type="text/json">{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a><script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=75384003]'), work: {"id":75384003,"title":"IGHV gene features and MYD88 L265P mutation separate the three marginal zone lymphoma entities and Waldenström macroglobulinemia/lymphoplasmacytic lymphomas","created_at":"2022-04-03T23:53:21.416-07:00","url":"https://www.academia.edu/75384003/IGHV_gene_features_and_MYD88_L265P_mutation_separate_the_three_marginal_zone_lymphoma_entities_and_Waldenstr%C3%B6m_macroglobulinemia_lymphoplasmacytic_lymphomas?f_ri=14109","dom_id":"work_75384003","summary":null,"downloadable_attachments":[{"id":83174283,"asset_id":75384003,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":89156635,"first_name":"Isabelle","last_name":"Soubeyran","domain_name":"independent","page_name":"IsabelleSoubeyran","display_name":"Isabelle Soubeyran","profile_url":"https://independent.academia.edu/IsabelleSoubeyran?f_ri=14109","photo":"https://0.academia-photos.com/89156635/62905097/51203251/s65_isabelle.soubeyran.png"}],"research_interests":[{"id":6599,"name":"Flow Cytometry","url":"https://www.academia.edu/Documents/in/Flow_Cytometry?f_ri=14109","nofollow":false},{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=14109","nofollow":false},{"id":74780,"name":"Mutation","url":"https://www.academia.edu/Documents/in/Mutation?f_ri=14109"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109"},{"id":489727,"name":"Prognosis","url":"https://www.academia.edu/Documents/in/Prognosis?f_ri=14109"},{"id":2079216,"name":"Lymph nodes","url":"https://www.academia.edu/Documents/in/Lymph_nodes?f_ri=14109"},{"id":2892963,"name":"immunoglobulin M","url":"https://www.academia.edu/Documents/in/immunoglobulin_M?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_28022413" data-work_id="28022413" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/28022413/Patients_perceptions_of_having_a_central_venous_catheter_or_a_totally_implantable_subcutaneous_port_system_results_from_a_randomised_study_in_acute_leukaemia">Patients’ perceptions of having a central venous catheter or a totally implantable subcutaneous port system–results from a randomised study in acute leukaemia</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/28022413" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="94895012d9b559c6b7cf7e42f6fac20e" rel="nofollow" data-download="{"attachment_id":48328742,"asset_id":28022413,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48328742/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="35328867" href="https://stavanger.academia.edu/EvaJohansson">Eva Johansson</a><script data-card-contents-for-user="35328867" type="text/json">{"id":35328867,"first_name":"Eva","last_name":"Johansson","domain_name":"stavanger","page_name":"EvaJohansson","display_name":"Eva Johansson","profile_url":"https://stavanger.academia.edu/EvaJohansson?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_28022413 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="28022413"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 28022413, container: ".js-paper-rank-work_28022413", }); });</script></li><li class="js-percentile-work_28022413 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 28022413; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_28022413"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_28022413 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="28022413"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 28022413; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=28022413]").text(description); $(".js-view-count-work_28022413").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_28022413").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="28022413"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">5</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="133057" href="https://www.academia.edu/Documents/in/Young_Adult">Young Adult</a>, <script data-card-contents-for-ri="133057" type="text/json">{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="144052" href="https://www.academia.edu/Documents/in/Patient_Satisfaction">Patient Satisfaction</a>, <script data-card-contents-for-ri="144052" type="text/json">{"id":144052,"name":"Patient Satisfaction","url":"https://www.academia.edu/Documents/in/Patient_Satisfaction?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="159187" href="https://www.academia.edu/Documents/in/Drug_Delivery_Systems">Drug Delivery Systems</a><script data-card-contents-for-ri="159187" type="text/json">{"id":159187,"name":"Drug Delivery Systems","url":"https://www.academia.edu/Documents/in/Drug_Delivery_Systems?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=28022413]'), work: {"id":28022413,"title":"Patients’ perceptions of having a central venous catheter or a totally implantable subcutaneous port system–results from a randomised study in acute leukaemia","created_at":"2016-08-26T01:47:12.468-07:00","url":"https://www.academia.edu/28022413/Patients_perceptions_of_having_a_central_venous_catheter_or_a_totally_implantable_subcutaneous_port_system_results_from_a_randomised_study_in_acute_leukaemia?f_ri=14109","dom_id":"work_28022413","summary":null,"downloadable_attachments":[{"id":48328742,"asset_id":28022413,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":35328867,"first_name":"Eva","last_name":"Johansson","domain_name":"stavanger","page_name":"EvaJohansson","display_name":"Eva Johansson","profile_url":"https://stavanger.academia.edu/EvaJohansson?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=14109","nofollow":false},{"id":144052,"name":"Patient Satisfaction","url":"https://www.academia.edu/Documents/in/Patient_Satisfaction?f_ri=14109","nofollow":false},{"id":159187,"name":"Drug Delivery Systems","url":"https://www.academia.edu/Documents/in/Drug_Delivery_Systems?f_ri=14109","nofollow":false},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_24852658" data-work_id="24852658" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/24852658/Intensive_high_dose_asparaginase_consolidation_improves_survival_for_pediatric_patients_with_T_cell_acute_lymphoblastic_leukemia_and_advanced_stage_lymphoblastic_lymphoma_a_Pediatric_Oncology_Group_study">Intensive high-dose asparaginase consolidation improves survival for pediatric patients with T cell acute lymphoblastic leukemia and advanced stage lymphoblastic lymphoma: a Pediatric Oncology Group study</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/24852658" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="353e8978660158500458ea7c2c654bf5" rel="nofollow" data-download="{"attachment_id":45176264,"asset_id":24852658,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45176264/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="37973686" href="https://stanford.academia.edu/MichaelAmylon">Michael Amylon</a><script data-card-contents-for-user="37973686" type="text/json">{"id":37973686,"first_name":"Michael","last_name":"Amylon","domain_name":"stanford","page_name":"MichaelAmylon","display_name":"Michael Amylon","profile_url":"https://stanford.academia.edu/MichaelAmylon?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_24852658 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="24852658"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 24852658, container: ".js-paper-rank-work_24852658", }); });</script></li><li class="js-percentile-work_24852658 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 24852658; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_24852658"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_24852658 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="24852658"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 24852658; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=24852658]").text(description); $(".js-view-count-work_24852658").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_24852658").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="24852658"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">7</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="64933" href="https://www.academia.edu/Documents/in/Child">Child</a>, <script data-card-contents-for-ri="64933" type="text/json">{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="134346" href="https://www.academia.edu/Documents/in/Infant">Infant</a><script data-card-contents-for-ri="134346" type="text/json">{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=24852658]'), work: {"id":24852658,"title":"Intensive high-dose asparaginase consolidation improves survival for pediatric patients with T cell acute lymphoblastic leukemia and advanced stage lymphoblastic lymphoma: a Pediatric Oncology Group study","created_at":"2016-04-28T12:02:25.632-07:00","url":"https://www.academia.edu/24852658/Intensive_high_dose_asparaginase_consolidation_improves_survival_for_pediatric_patients_with_T_cell_acute_lymphoblastic_leukemia_and_advanced_stage_lymphoblastic_lymphoma_a_Pediatric_Oncology_Group_study?f_ri=14109","dom_id":"work_24852658","summary":null,"downloadable_attachments":[{"id":45176264,"asset_id":24852658,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":37973686,"first_name":"Michael","last_name":"Amylon","domain_name":"stanford","page_name":"MichaelAmylon","display_name":"Michael Amylon","profile_url":"https://stanford.academia.edu/MichaelAmylon?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=14109","nofollow":false},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=14109","nofollow":false},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109"},{"id":305057,"name":"L-asparaginase","url":"https://www.academia.edu/Documents/in/L-asparaginase?f_ri=14109"},{"id":1630613,"name":"Acute Lymphoblastic Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Lymphoblastic_Leukemia?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_15721423" data-work_id="15721423" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/15721423/Music_imagery_for_adults_with_acute_leukemia_in_protective_environments_a_feasibility_study">Music imagery for adults with acute leukemia in protective environments: a feasibility study</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/15721423" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="b57c66f7d88f68beda5b2f662d7368f0" rel="nofollow" data-download="{"attachment_id":42937533,"asset_id":15721423,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42937533/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="34910659" href="https://iu-indianapolis.academia.edu/PatrickMonahan">Patrick Monahan</a><script data-card-contents-for-user="34910659" type="text/json">{"id":34910659,"first_name":"Patrick","last_name":"Monahan","domain_name":"iu-indianapolis","page_name":"PatrickMonahan","display_name":"Patrick Monahan","profile_url":"https://iu-indianapolis.academia.edu/PatrickMonahan?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_15721423 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="15721423"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 15721423, container: ".js-paper-rank-work_15721423", }); });</script></li><li class="js-percentile-work_15721423 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 15721423; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_15721423"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_15721423 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="15721423"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 15721423; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=15721423]").text(description); $(".js-view-count-work_15721423").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_15721423").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="15721423"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">18</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="12426" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a>, <script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="19947" href="https://www.academia.edu/Documents/in/Music_Therapy">Music Therapy</a>, <script data-card-contents-for-ri="19947" type="text/json">{"id":19947,"name":"Music Therapy","url":"https://www.academia.edu/Documents/in/Music_Therapy?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="23076" href="https://www.academia.edu/Documents/in/Fatigue">Fatigue</a><script data-card-contents-for-ri="23076" type="text/json">{"id":23076,"name":"Fatigue","url":"https://www.academia.edu/Documents/in/Fatigue?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=15721423]'), work: {"id":15721423,"title":"Music imagery for adults with acute leukemia in protective environments: a feasibility study","created_at":"2015-09-15T05:47:30.530-07:00","url":"https://www.academia.edu/15721423/Music_imagery_for_adults_with_acute_leukemia_in_protective_environments_a_feasibility_study?f_ri=14109","dom_id":"work_15721423","summary":null,"downloadable_attachments":[{"id":42937533,"asset_id":15721423,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":34910659,"first_name":"Patrick","last_name":"Monahan","domain_name":"iu-indianapolis","page_name":"PatrickMonahan","display_name":"Patrick Monahan","profile_url":"https://iu-indianapolis.academia.edu/PatrickMonahan?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":19947,"name":"Music Therapy","url":"https://www.academia.edu/Documents/in/Music_Therapy?f_ri=14109","nofollow":false},{"id":23076,"name":"Fatigue","url":"https://www.academia.edu/Documents/in/Fatigue?f_ri=14109","nofollow":false},{"id":38676,"name":"Anxiety","url":"https://www.academia.edu/Documents/in/Anxiety?f_ri=14109"},{"id":42695,"name":"Post traumatic stress disorder","url":"https://www.academia.edu/Documents/in/Post_traumatic_stress_disorder?f_ri=14109"},{"id":44526,"name":"Feasibility Study","url":"https://www.academia.edu/Documents/in/Feasibility_Study?f_ri=14109"},{"id":50238,"name":"Affect","url":"https://www.academia.edu/Documents/in/Affect?f_ri=14109"},{"id":59057,"name":"Acute Myeloid Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia?f_ri=14109"},{"id":69825,"name":"Negative Affect","url":"https://www.academia.edu/Documents/in/Negative_Affect?f_ri=14109"},{"id":100540,"name":"Feasibility Studies","url":"https://www.academia.edu/Documents/in/Feasibility_Studies?f_ri=14109"},{"id":118531,"name":"Cancer Diagnosis","url":"https://www.academia.edu/Documents/in/Cancer_Diagnosis?f_ri=14109"},{"id":121607,"name":"Missing Data","url":"https://www.academia.edu/Documents/in/Missing_Data?f_ri=14109"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=14109"},{"id":327850,"name":"Questionnaires","url":"https://www.academia.edu/Documents/in/Questionnaires?f_ri=14109"},{"id":623821,"name":"ANXIETY","url":"https://www.academia.edu/Documents/in/ANXIETY-1?f_ri=14109"},{"id":1000489,"name":"Imagery In Psychotherapy","url":"https://www.academia.edu/Documents/in/Imagery_In_Psychotherapy?f_ri=14109"},{"id":1505288,"name":"Relaxation Therapy","url":"https://www.academia.edu/Documents/in/Relaxation_Therapy?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_70731329" data-work_id="70731329" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/70731329/Recombinant_DNA_Approaches_to_Feline_Leukemia_Virus_Immunization">Recombinant DNA Approaches to Feline Leukemia Virus Immunization</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">We have utilized 2 recombinant DNA strategies for immunization against FeLV in cats: (a) modified live virus was attenuated by mutation and recombination, and (b) an immunogen, consisting of subunit envelope protein, was prepared in... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_70731329" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">We have utilized 2 recombinant DNA strategies for immunization against FeLV in cats: (a) modified live virus was attenuated by mutation and recombination, and (b) an immunogen, consisting of subunit envelope protein, was prepared in genetically engineered yeast. Results indicated that the genetically manipulated live virus preparations were not protective against FeLV challenge because they were either not attenuated in virulence or were not sufficiently antigenic. Immunization with yeast-synthesized FeLV envelope protein followed by the modified live virus gave protective immunity in cats under experimental conditions. Future immunization attempts will concentrate on enhancing the immunogenic potency of the yeast- synthesized FeLV envelope protein.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/70731329" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="37978285" href="https://independent.academia.edu/PaulLuciw">Paul Luciw</a><script data-card-contents-for-user="37978285" type="text/json">{"id":37978285,"first_name":"Paul","last_name":"Luciw","domain_name":"independent","page_name":"PaulLuciw","display_name":"Paul Luciw","profile_url":"https://independent.academia.edu/PaulLuciw?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_70731329 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="70731329"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 70731329, container: ".js-paper-rank-work_70731329", }); });</script></li><li class="js-percentile-work_70731329 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 70731329; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_70731329"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_70731329 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="70731329"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 70731329; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=70731329]").text(description); $(".js-view-count-work_70731329").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_70731329").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="70731329"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">6</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="41012" href="https://www.academia.edu/Documents/in/Recombinant_DNA_Technology">Recombinant DNA Technology</a>, <script data-card-contents-for-ri="41012" type="text/json">{"id":41012,"name":"Recombinant DNA Technology","url":"https://www.academia.edu/Documents/in/Recombinant_DNA_Technology?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="41088" href="https://www.academia.edu/Documents/in/Cats">Cats</a>, <script data-card-contents-for-ri="41088" type="text/json">{"id":41088,"name":"Cats","url":"https://www.academia.edu/Documents/in/Cats?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="41749" href="https://www.academia.edu/Documents/in/Genetic_Engineering">Genetic Engineering</a><script data-card-contents-for-ri="41749" type="text/json">{"id":41749,"name":"Genetic Engineering","url":"https://www.academia.edu/Documents/in/Genetic_Engineering?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=70731329]'), work: {"id":70731329,"title":"Recombinant DNA Approaches to Feline Leukemia Virus Immunization","created_at":"2022-02-06T11:02:45.835-08:00","url":"https://www.academia.edu/70731329/Recombinant_DNA_Approaches_to_Feline_Leukemia_Virus_Immunization?f_ri=14109","dom_id":"work_70731329","summary":"We have utilized 2 recombinant DNA strategies for immunization against FeLV in cats: (a) modified live virus was attenuated by mutation and recombination, and (b) an immunogen, consisting of subunit envelope protein, was prepared in genetically engineered yeast. Results indicated that the genetically manipulated live virus preparations were not protective against FeLV challenge because they were either not attenuated in virulence or were not sufficiently antigenic. Immunization with yeast-synthesized FeLV envelope protein followed by the modified live virus gave protective immunity in cats under experimental conditions. Future immunization attempts will concentrate on enhancing the immunogenic potency of the yeast- synthesized FeLV envelope protein.","downloadable_attachments":[],"ordered_authors":[{"id":37978285,"first_name":"Paul","last_name":"Luciw","domain_name":"independent","page_name":"PaulLuciw","display_name":"Paul Luciw","profile_url":"https://independent.academia.edu/PaulLuciw?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":41012,"name":"Recombinant DNA Technology","url":"https://www.academia.edu/Documents/in/Recombinant_DNA_Technology?f_ri=14109","nofollow":false},{"id":41088,"name":"Cats","url":"https://www.academia.edu/Documents/in/Cats?f_ri=14109","nofollow":false},{"id":41749,"name":"Genetic Engineering","url":"https://www.academia.edu/Documents/in/Genetic_Engineering?f_ri=14109","nofollow":false},{"id":295728,"name":"Molecular cloning","url":"https://www.academia.edu/Documents/in/Molecular_cloning?f_ri=14109"},{"id":3647178,"name":"DNA Restriction Enzymes","url":"https://www.academia.edu/Documents/in/DNA_Restriction_Enzymes?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_61537636" data-work_id="61537636" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/61537636/Complement_dependent_cellular_cytotoxicity_lymphoblastoid_lines_that_activate_complement_component_3_C3_and_express_C3_receptors_have_increased_sensitivity_to_lymphocyte_mediated_lysis_in_the_presence_of_fresh_human_serum">Complement-dependent cellular cytotoxicity: lymphoblastoid lines that activate complement component 3 (C3) and express C3 receptors have increased sensitivity to lymphocyte-mediated lysis in the presence of fresh human serum</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/61537636" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="43a9f80843d5aa8d7ffb47c1f79bc00c" rel="nofollow" data-download="{"attachment_id":74541339,"asset_id":61537636,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/74541339/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="24216054" href="https://independent.academia.edu/OscarRamos21">Oscar Ramos</a><script data-card-contents-for-user="24216054" type="text/json">{"id":24216054,"first_name":"Oscar","last_name":"Ramos","domain_name":"independent","page_name":"OscarRamos21","display_name":"Oscar Ramos","profile_url":"https://independent.academia.edu/OscarRamos21?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_61537636 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="61537636"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 61537636, container: ".js-paper-rank-work_61537636", }); });</script></li><li class="js-percentile-work_61537636 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 61537636; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_61537636"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_61537636 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="61537636"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 61537636; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=61537636]").text(description); $(".js-view-count-work_61537636").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_61537636").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="61537636"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">8</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="4987" href="https://www.academia.edu/Documents/in/Kinetics">Kinetics</a>, <script data-card-contents-for-ri="4987" type="text/json">{"id":4987,"name":"Kinetics","url":"https://www.academia.edu/Documents/in/Kinetics?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="10055" href="https://www.academia.edu/Documents/in/Cell_Adhesion">Cell Adhesion</a>, <script data-card-contents-for-ri="10055" type="text/json">{"id":10055,"name":"Cell Adhesion","url":"https://www.academia.edu/Documents/in/Cell_Adhesion?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="28235" href="https://www.academia.edu/Documents/in/Multidisciplinary">Multidisciplinary</a><script data-card-contents-for-ri="28235" type="text/json">{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=61537636]'), work: {"id":61537636,"title":"Complement-dependent cellular cytotoxicity: lymphoblastoid lines that activate complement component 3 (C3) and express C3 receptors have increased sensitivity to lymphocyte-mediated lysis in the presence of fresh human serum","created_at":"2021-11-11T12:24:14.407-08:00","url":"https://www.academia.edu/61537636/Complement_dependent_cellular_cytotoxicity_lymphoblastoid_lines_that_activate_complement_component_3_C3_and_express_C3_receptors_have_increased_sensitivity_to_lymphocyte_mediated_lysis_in_the_presence_of_fresh_human_serum?f_ri=14109","dom_id":"work_61537636","summary":null,"downloadable_attachments":[{"id":74541339,"asset_id":61537636,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":24216054,"first_name":"Oscar","last_name":"Ramos","domain_name":"independent","page_name":"OscarRamos21","display_name":"Oscar Ramos","profile_url":"https://independent.academia.edu/OscarRamos21?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":4987,"name":"Kinetics","url":"https://www.academia.edu/Documents/in/Kinetics?f_ri=14109","nofollow":false},{"id":10055,"name":"Cell Adhesion","url":"https://www.academia.edu/Documents/in/Cell_Adhesion?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary?f_ri=14109","nofollow":false},{"id":57808,"name":"Cell line","url":"https://www.academia.edu/Documents/in/Cell_line?f_ri=14109"},{"id":563659,"name":"Human Serum","url":"https://www.academia.edu/Documents/in/Human_Serum?f_ri=14109"},{"id":862339,"name":"Component","url":"https://www.academia.edu/Documents/in/Component?f_ri=14109"},{"id":868560,"name":"Lymphocytes","url":"https://www.academia.edu/Documents/in/Lymphocytes?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_71392389" data-work_id="71392389" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/71392389/Health_related_quality_of_life_among_child_and_adolescent_survivors_of_childhood_cancer">Health-related quality of life among child and adolescent survivors of childhood cancer</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/71392389" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="e6728d4ffef7c8acc426da5465d7aac1" rel="nofollow" data-download="{"attachment_id":80754614,"asset_id":71392389,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/80754614/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="134090188" href="https://independent.academia.edu/AmandaRossShaw">Amanda Ross Shaw</a><script data-card-contents-for-user="134090188" type="text/json">{"id":134090188,"first_name":"Amanda","last_name":"Ross Shaw","domain_name":"independent","page_name":"AmandaRossShaw","display_name":"Amanda Ross Shaw","profile_url":"https://independent.academia.edu/AmandaRossShaw?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_71392389 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="71392389"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 71392389, container: ".js-paper-rank-work_71392389", }); });</script></li><li class="js-percentile-work_71392389 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 71392389; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_71392389"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_71392389 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="71392389"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 71392389; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=71392389]").text(description); $(".js-view-count-work_71392389").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_71392389").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="71392389"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">17</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="2885" href="https://www.academia.edu/Documents/in/Child_health">Child health</a>, <script data-card-contents-for-ri="2885" type="text/json">{"id":2885,"name":"Child health","url":"https://www.academia.edu/Documents/in/Child_health?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="7470" href="https://www.academia.edu/Documents/in/Quality_of_life">Quality of life</a>, <script data-card-contents-for-ri="7470" type="text/json">{"id":7470,"name":"Quality of life","url":"https://www.academia.edu/Documents/in/Quality_of_life?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a><script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=71392389]'), work: {"id":71392389,"title":"Health-related quality of life among child and adolescent survivors of childhood cancer","created_at":"2022-02-13T15:56:57.288-08:00","url":"https://www.academia.edu/71392389/Health_related_quality_of_life_among_child_and_adolescent_survivors_of_childhood_cancer?f_ri=14109","dom_id":"work_71392389","summary":null,"downloadable_attachments":[{"id":80754614,"asset_id":71392389,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":134090188,"first_name":"Amanda","last_name":"Ross Shaw","domain_name":"independent","page_name":"AmandaRossShaw","display_name":"Amanda Ross Shaw","profile_url":"https://independent.academia.edu/AmandaRossShaw?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":2885,"name":"Child health","url":"https://www.academia.edu/Documents/in/Child_health?f_ri=14109","nofollow":false},{"id":7470,"name":"Quality of life","url":"https://www.academia.edu/Documents/in/Quality_of_life?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false},{"id":54114,"name":"Canada","url":"https://www.academia.edu/Documents/in/Canada?f_ri=14109"},{"id":55269,"name":"Lymphoma","url":"https://www.academia.edu/Documents/in/Lymphoma?f_ri=14109"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=14109"},{"id":82844,"name":"Health related Quality of Life","url":"https://www.academia.edu/Documents/in/Health_related_Quality_of_Life?f_ri=14109"},{"id":99708,"name":"Clinical","url":"https://www.academia.edu/Documents/in/Clinical?f_ri=14109"},{"id":102957,"name":"Childhood Cancer","url":"https://www.academia.edu/Documents/in/Childhood_Cancer?f_ri=14109"},{"id":115895,"name":"Clinical oncology","url":"https://www.academia.edu/Documents/in/Clinical_oncology?f_ri=14109"},{"id":131185,"name":"Cohort Study","url":"https://www.academia.edu/Documents/in/Cohort_Study?f_ri=14109"},{"id":232534,"name":"Health Status","url":"https://www.academia.edu/Documents/in/Health_Status?f_ri=14109"},{"id":469018,"name":"Neoplasms","url":"https://www.academia.edu/Documents/in/Neoplasms?f_ri=14109"},{"id":615506,"name":"Soft Tissue Sarcoma","url":"https://www.academia.edu/Documents/in/Soft_Tissue_Sarcoma?f_ri=14109"},{"id":1423006,"name":"General Population","url":"https://www.academia.edu/Documents/in/General_Population?f_ri=14109"},{"id":1819399,"name":"Case Control Studies","url":"https://www.academia.edu/Documents/in/Case_Control_Studies?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_26824919" data-work_id="26824919" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/26824919/Evaluation_of_cardiac_troponin_I_and_T_levels_as_markers_of_myocardial_damage_in_doxorubicin_induced_cardiomyopathy_rats_and_their_relationship_with_echocardiographic_and_histological_findings">Evaluation of cardiac troponin I and T levels as markers of myocardial damage in doxorubicin-induced cardiomyopathy rats, and their relationship with echocardiographic and histological findings</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/26824919" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="9131b8f0ecf7fa83e2e6d44262168aac" rel="nofollow" data-download="{"attachment_id":47098702,"asset_id":26824919,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/47098702/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="50824743" href="https://independent.academia.edu/MichelDauzat">Michel Dauzat</a><script data-card-contents-for-user="50824743" type="text/json">{"id":50824743,"first_name":"Michel","last_name":"Dauzat","domain_name":"independent","page_name":"MichelDauzat","display_name":"Michel Dauzat","profile_url":"https://independent.academia.edu/MichelDauzat?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_26824919 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="26824919"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 26824919, container: ".js-paper-rank-work_26824919", }); });</script></li><li class="js-percentile-work_26824919 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 26824919; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_26824919"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_26824919 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="26824919"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 26824919; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=26824919]").text(description); $(".js-view-count-work_26824919").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_26824919").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="26824919"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">15</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="12071" href="https://www.academia.edu/Documents/in/Immunohistochemistry">Immunohistochemistry</a>, <script data-card-contents-for-ri="12071" type="text/json">{"id":12071,"name":"Immunohistochemistry","url":"https://www.academia.edu/Documents/in/Immunohistochemistry?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="37834" href="https://www.academia.edu/Documents/in/Western_blotting">Western blotting</a>, <script data-card-contents-for-ri="37834" type="text/json">{"id":37834,"name":"Western blotting","url":"https://www.academia.edu/Documents/in/Western_blotting?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="60971" href="https://www.academia.edu/Documents/in/Cerebrospinal_Fluid">Cerebrospinal Fluid</a><script data-card-contents-for-ri="60971" type="text/json">{"id":60971,"name":"Cerebrospinal Fluid","url":"https://www.academia.edu/Documents/in/Cerebrospinal_Fluid?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=26824919]'), work: {"id":26824919,"title":"Evaluation of cardiac troponin I and T levels as markers of myocardial damage in doxorubicin-induced cardiomyopathy rats, and their relationship with echocardiographic and histological findings","created_at":"2016-07-07T23:37:11.939-07:00","url":"https://www.academia.edu/26824919/Evaluation_of_cardiac_troponin_I_and_T_levels_as_markers_of_myocardial_damage_in_doxorubicin_induced_cardiomyopathy_rats_and_their_relationship_with_echocardiographic_and_histological_findings?f_ri=14109","dom_id":"work_26824919","summary":null,"downloadable_attachments":[{"id":47098702,"asset_id":26824919,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":50824743,"first_name":"Michel","last_name":"Dauzat","domain_name":"independent","page_name":"MichelDauzat","display_name":"Michel Dauzat","profile_url":"https://independent.academia.edu/MichelDauzat?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":12071,"name":"Immunohistochemistry","url":"https://www.academia.edu/Documents/in/Immunohistochemistry?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":37834,"name":"Western blotting","url":"https://www.academia.edu/Documents/in/Western_blotting?f_ri=14109","nofollow":false},{"id":60971,"name":"Cerebrospinal Fluid","url":"https://www.academia.edu/Documents/in/Cerebrospinal_Fluid?f_ri=14109","nofollow":false},{"id":61946,"name":"Damage Assessment","url":"https://www.academia.edu/Documents/in/Damage_Assessment?f_ri=14109"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109"},{"id":436755,"name":"Degeneration","url":"https://www.academia.edu/Documents/in/Degeneration?f_ri=14109"},{"id":436838,"name":"cystatin C","url":"https://www.academia.edu/Documents/in/cystatin_C?f_ri=14109"},{"id":584613,"name":"Cysteine endopeptidases","url":"https://www.academia.edu/Documents/in/Cysteine_endopeptidases?f_ri=14109"},{"id":732354,"name":"Rat Model","url":"https://www.academia.edu/Documents/in/Rat_Model?f_ri=14109"},{"id":901876,"name":"Sensitivity and Specificity","url":"https://www.academia.edu/Documents/in/Sensitivity_and_Specificity?f_ri=14109"},{"id":956026,"name":"Somatic Cell Count","url":"https://www.academia.edu/Documents/in/Somatic_Cell_Count?f_ri=14109"},{"id":1272906,"name":"Enzyme Linked Immunosorbent Assay","url":"https://www.academia.edu/Documents/in/Enzyme_Linked_Immunosorbent_Assay?f_ri=14109"},{"id":1631043,"name":"Control Group","url":"https://www.academia.edu/Documents/in/Control_Group?f_ri=14109"},{"id":1993786,"name":"Cumulant","url":"https://www.academia.edu/Documents/in/Cumulant?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_25067046" data-work_id="25067046" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/25067046/Leukemia_risk_and_relevant_benzene_exposure_period_Re_Follow_up_time_on_risk_estimates_Am_J_Ind_Med_42_481_489_2002">Leukemia risk and relevant benzene exposure period?Re: Follow-up time on risk estimates, Am J Ind Med 42:481-489, 2002</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/25067046" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="6767c23700904c6f6f7112caa28d4ca1" rel="nofollow" data-download="{"attachment_id":45389057,"asset_id":25067046,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45389057/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="48310821" href="https://independent.academia.edu/DeborahGlass1">Deborah C Glass</a><script data-card-contents-for-user="48310821" type="text/json">{"id":48310821,"first_name":"Deborah","last_name":"Glass","domain_name":"independent","page_name":"DeborahGlass1","display_name":"Deborah C Glass","profile_url":"https://independent.academia.edu/DeborahGlass1?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_25067046 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="25067046"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 25067046, container: ".js-paper-rank-work_25067046", }); });</script></li><li class="js-percentile-work_25067046 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 25067046; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_25067046"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_25067046 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="25067046"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 25067046; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=25067046]").text(description); $(".js-view-count-work_25067046").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_25067046").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="25067046"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">14</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="6697" href="https://www.academia.edu/Documents/in/Australia">Australia</a>, <script data-card-contents-for-ri="6697" type="text/json">{"id":6697,"name":"Australia","url":"https://www.academia.edu/Documents/in/Australia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="16664" href="https://www.academia.edu/Documents/in/Risk_assessment">Risk assessment</a>, <script data-card-contents-for-ri="16664" type="text/json">{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="111110" href="https://www.academia.edu/Documents/in/Multiple_Myeloma">Multiple Myeloma</a><script data-card-contents-for-ri="111110" type="text/json">{"id":111110,"name":"Multiple Myeloma","url":"https://www.academia.edu/Documents/in/Multiple_Myeloma?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=25067046]'), work: {"id":25067046,"title":"Leukemia risk and relevant benzene exposure period?Re: Follow-up time on risk estimates, Am J Ind Med 42:481-489, 2002","created_at":"2016-05-05T16:00:45.233-07:00","url":"https://www.academia.edu/25067046/Leukemia_risk_and_relevant_benzene_exposure_period_Re_Follow_up_time_on_risk_estimates_Am_J_Ind_Med_42_481_489_2002?f_ri=14109","dom_id":"work_25067046","summary":null,"downloadable_attachments":[{"id":45389057,"asset_id":25067046,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":48310821,"first_name":"Deborah","last_name":"Glass","domain_name":"independent","page_name":"DeborahGlass1","display_name":"Deborah C Glass","profile_url":"https://independent.academia.edu/DeborahGlass1?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":6697,"name":"Australia","url":"https://www.academia.edu/Documents/in/Australia?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=14109","nofollow":false},{"id":111110,"name":"Multiple Myeloma","url":"https://www.academia.edu/Documents/in/Multiple_Myeloma?f_ri=14109","nofollow":false},{"id":151448,"name":"American","url":"https://www.academia.edu/Documents/in/American?f_ri=14109"},{"id":208460,"name":"Rubber","url":"https://www.academia.edu/Documents/in/Rubber?f_ri=14109"},{"id":396914,"name":"Occupational Exposure","url":"https://www.academia.edu/Documents/in/Occupational_Exposure?f_ri=14109"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=14109"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=14109"},{"id":606320,"name":"Benzene","url":"https://www.academia.edu/Documents/in/Benzene?f_ri=14109"},{"id":622589,"name":"Risk Assessment","url":"https://www.academia.edu/Documents/in/Risk_Assessment-2?f_ri=14109"},{"id":962276,"name":"Occupational Diseases","url":"https://www.academia.edu/Documents/in/Occupational_Diseases?f_ri=14109"},{"id":1819399,"name":"Case Control Studies","url":"https://www.academia.edu/Documents/in/Case_Control_Studies?f_ri=14109"},{"id":2455248,"name":"Risk estimation","url":"https://www.academia.edu/Documents/in/Risk_estimation?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_20555098" data-work_id="20555098" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/20555098/Trends_in_cancer_mortality_in_Kanawha_County_West_Virginia_1950_1984">Trends in cancer mortality in Kanawha County, West Virginia, 1950–1984</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/20555098" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="423e6041296a84452237404732919a78" rel="nofollow" data-download="{"attachment_id":41946973,"asset_id":20555098,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/41946973/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="41357675" href="https://independent.academia.edu/TalbottE">Evelyn Talbott</a><script data-card-contents-for-user="41357675" type="text/json">{"id":41357675,"first_name":"Evelyn","last_name":"Talbott","domain_name":"independent","page_name":"TalbottE","display_name":"Evelyn Talbott","profile_url":"https://independent.academia.edu/TalbottE?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_20555098 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="20555098"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 20555098, container: ".js-paper-rank-work_20555098", }); });</script></li><li class="js-percentile-work_20555098 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 20555098; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_20555098"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_20555098 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="20555098"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 20555098; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=20555098]").text(description); $(".js-view-count-work_20555098").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_20555098").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="20555098"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">8</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="28235" href="https://www.academia.edu/Documents/in/Multidisciplinary">Multidisciplinary</a>, <script data-card-contents-for-ri="28235" type="text/json">{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="396914" href="https://www.academia.edu/Documents/in/Occupational_Exposure">Occupational Exposure</a><script data-card-contents-for-ri="396914" type="text/json">{"id":396914,"name":"Occupational Exposure","url":"https://www.academia.edu/Documents/in/Occupational_Exposure?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=20555098]'), work: {"id":20555098,"title":"Trends in cancer mortality in Kanawha County, West Virginia, 1950–1984","created_at":"2016-01-22T08:12:04.110-08:00","url":"https://www.academia.edu/20555098/Trends_in_cancer_mortality_in_Kanawha_County_West_Virginia_1950_1984?f_ri=14109","dom_id":"work_20555098","summary":null,"downloadable_attachments":[{"id":41946973,"asset_id":20555098,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":41357675,"first_name":"Evelyn","last_name":"Talbott","domain_name":"independent","page_name":"TalbottE","display_name":"Evelyn Talbott","profile_url":"https://independent.academia.edu/TalbottE?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=14109","nofollow":false},{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary?f_ri=14109","nofollow":false},{"id":396914,"name":"Occupational Exposure","url":"https://www.academia.edu/Documents/in/Occupational_Exposure?f_ri=14109","nofollow":false},{"id":416537,"name":"Chemical Industry","url":"https://www.academia.edu/Documents/in/Chemical_Industry?f_ri=14109"},{"id":541328,"name":"Diffuse Large B-Cell Lymphoma","url":"https://www.academia.edu/Documents/in/Diffuse_Large_B-Cell_Lymphoma?f_ri=14109"},{"id":658986,"name":"West Virginia","url":"https://www.academia.edu/Documents/in/West_Virginia?f_ri=14109"},{"id":1656539,"name":"Air Pollutants","url":"https://www.academia.edu/Documents/in/Air_Pollutants?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_18561385" data-work_id="18561385" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/18561385/A_Physical_Transcript_and_Deletion_Map_of_Chromosome_Region_12p12_3_Flanked_byETV6andCDKN1B_Hypermethylation_of_theLRP6CpG_Island_in_Two_Leukemia_Patients_with_Hemizygous_del_12p_">A Physical, Transcript, and Deletion Map of Chromosome Region 12p12.3 Flanked byETV6andCDKN1B:Hypermethylation of theLRP6CpG Island in Two Leukemia Patients with Hemizygous del(12p)</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/18561385" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="cb48d92038cf339b66a059be0abbc0ab" rel="nofollow" data-download="{"attachment_id":40129476,"asset_id":18561385,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/40129476/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="38430694" href="https://independent.academia.edu/AHagemeijer">Anne Hagemeijer</a><script data-card-contents-for-user="38430694" type="text/json">{"id":38430694,"first_name":"Anne","last_name":"Hagemeijer","domain_name":"independent","page_name":"AHagemeijer","display_name":"Anne Hagemeijer","profile_url":"https://independent.academia.edu/AHagemeijer?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_18561385 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="18561385"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 18561385, container: ".js-paper-rank-work_18561385", }); });</script></li><li class="js-percentile-work_18561385 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 18561385; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_18561385"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_18561385 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="18561385"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 18561385; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=18561385]").text(description); $(".js-view-count-work_18561385").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_18561385").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="18561385"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">20</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="37" href="https://www.academia.edu/Documents/in/Information_Systems">Information Systems</a>, <script data-card-contents-for-ri="37" type="text/json">{"id":37,"name":"Information Systems","url":"https://www.academia.edu/Documents/in/Information_Systems?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="156" href="https://www.academia.edu/Documents/in/Genetics">Genetics</a>, <script data-card-contents-for-ri="156" type="text/json">{"id":156,"name":"Genetics","url":"https://www.academia.edu/Documents/in/Genetics?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="3216" href="https://www.academia.edu/Documents/in/Genomics">Genomics</a>, <script data-card-contents-for-ri="3216" type="text/json">{"id":3216,"name":"Genomics","url":"https://www.academia.edu/Documents/in/Genomics?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="3855" href="https://www.academia.edu/Documents/in/Polymorphism">Polymorphism</a><script data-card-contents-for-ri="3855" type="text/json">{"id":3855,"name":"Polymorphism","url":"https://www.academia.edu/Documents/in/Polymorphism?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=18561385]'), work: {"id":18561385,"title":"A Physical, Transcript, and Deletion Map of Chromosome Region 12p12.3 Flanked byETV6andCDKN1B:Hypermethylation of theLRP6CpG Island in Two Leukemia Patients with Hemizygous del(12p)","created_at":"2015-11-18T00:34:06.532-08:00","url":"https://www.academia.edu/18561385/A_Physical_Transcript_and_Deletion_Map_of_Chromosome_Region_12p12_3_Flanked_byETV6andCDKN1B_Hypermethylation_of_theLRP6CpG_Island_in_Two_Leukemia_Patients_with_Hemizygous_del_12p_?f_ri=14109","dom_id":"work_18561385","summary":null,"downloadable_attachments":[{"id":40129476,"asset_id":18561385,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":38430694,"first_name":"Anne","last_name":"Hagemeijer","domain_name":"independent","page_name":"AHagemeijer","display_name":"Anne Hagemeijer","profile_url":"https://independent.academia.edu/AHagemeijer?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":37,"name":"Information Systems","url":"https://www.academia.edu/Documents/in/Information_Systems?f_ri=14109","nofollow":false},{"id":156,"name":"Genetics","url":"https://www.academia.edu/Documents/in/Genetics?f_ri=14109","nofollow":false},{"id":3216,"name":"Genomics","url":"https://www.academia.edu/Documents/in/Genomics?f_ri=14109","nofollow":false},{"id":3855,"name":"Polymorphism","url":"https://www.academia.edu/Documents/in/Polymorphism?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109"},{"id":23323,"name":"Transcription Factors","url":"https://www.academia.edu/Documents/in/Transcription_Factors?f_ri=14109"},{"id":29082,"name":"Sequence Analysis","url":"https://www.academia.edu/Documents/in/Sequence_Analysis?f_ri=14109"},{"id":32923,"name":"Gene Silencing","url":"https://www.academia.edu/Documents/in/Gene_Silencing?f_ri=14109"},{"id":81369,"name":"Expressed Sequence Tags","url":"https://www.academia.edu/Documents/in/Expressed_Sequence_Tags?f_ri=14109"},{"id":87651,"name":"Methylation","url":"https://www.academia.edu/Documents/in/Methylation?f_ri=14109"},{"id":121667,"name":"CpG islands","url":"https://www.academia.edu/Documents/in/CpG_islands?f_ri=14109"},{"id":237185,"name":"Physical chromosome mapping","url":"https://www.academia.edu/Documents/in/Physical_chromosome_mapping?f_ri=14109"},{"id":283547,"name":"Introns","url":"https://www.academia.edu/Documents/in/Introns?f_ri=14109"},{"id":309086,"name":"High Resolution","url":"https://www.academia.edu/Documents/in/High_Resolution?f_ri=14109"},{"id":372667,"name":"Tumor Suppressor Gene","url":"https://www.academia.edu/Documents/in/Tumor_Suppressor_Gene?f_ri=14109"},{"id":732028,"name":"Genome sequence","url":"https://www.academia.edu/Documents/in/Genome_sequence?f_ri=14109"},{"id":983317,"name":"Cell Cycle Proteins","url":"https://www.academia.edu/Documents/in/Cell_Cycle_Proteins?f_ri=14109"},{"id":1007674,"name":"CpG island","url":"https://www.academia.edu/Documents/in/CpG_island?f_ri=14109"},{"id":1186610,"name":"DNA binding proteins","url":"https://www.academia.edu/Documents/in/DNA_binding_proteins?f_ri=14109"},{"id":2212882,"name":"Chromosome Banding","url":"https://www.academia.edu/Documents/in/Chromosome_Banding?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_32936482" data-work_id="32936482" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/32936482/MLL_partial_tandem_duplications_in_acute_leukemia_cell_lines">MLL partial tandem duplications in acute leukemia cell lines</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/32936482" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="750dd3d4a577be7b337da687e5bc775b" rel="nofollow" data-download="{"attachment_id":53068974,"asset_id":32936482,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/53068974/download_file?st=MTczMjgzOTk0Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="64118104" href="https://independent.academia.edu/HilmarQuentmeier">Hilmar Quentmeier</a><script data-card-contents-for-user="64118104" type="text/json">{"id":64118104,"first_name":"Hilmar","last_name":"Quentmeier","domain_name":"independent","page_name":"HilmarQuentmeier","display_name":"Hilmar Quentmeier","profile_url":"https://independent.academia.edu/HilmarQuentmeier?f_ri=14109","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_32936482 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="32936482"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 32936482, container: ".js-paper-rank-work_32936482", }); });</script></li><li class="js-percentile-work_32936482 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 32936482; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_32936482"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_32936482 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="32936482"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 32936482; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=32936482]").text(description); $(".js-view-count-work_32936482").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_32936482").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="32936482"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">16</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="626" href="https://www.academia.edu/Documents/in/Oncology">Oncology</a>, <script data-card-contents-for-ri="626" type="text/json">{"id":626,"name":"Oncology","url":"https://www.academia.edu/Documents/in/Oncology?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="1290" href="https://www.academia.edu/Documents/in/Immunology">Immunology</a>, <script data-card-contents-for-ri="1290" type="text/json">{"id":1290,"name":"Immunology","url":"https://www.academia.edu/Documents/in/Immunology?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="3642" href="https://www.academia.edu/Documents/in/Stem_Cells">Stem Cells</a>, <script data-card-contents-for-ri="3642" type="text/json">{"id":3642,"name":"Stem Cells","url":"https://www.academia.edu/Documents/in/Stem_Cells?f_ri=14109","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="14109" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a><script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=32936482]'), work: {"id":32936482,"title":"MLL partial tandem duplications in acute leukemia cell lines","created_at":"2017-05-10T06:04:35.647-07:00","url":"https://www.academia.edu/32936482/MLL_partial_tandem_duplications_in_acute_leukemia_cell_lines?f_ri=14109","dom_id":"work_32936482","summary":null,"downloadable_attachments":[{"id":53068974,"asset_id":32936482,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":64118104,"first_name":"Hilmar","last_name":"Quentmeier","domain_name":"independent","page_name":"HilmarQuentmeier","display_name":"Hilmar Quentmeier","profile_url":"https://independent.academia.edu/HilmarQuentmeier?f_ri=14109","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":626,"name":"Oncology","url":"https://www.academia.edu/Documents/in/Oncology?f_ri=14109","nofollow":false},{"id":1290,"name":"Immunology","url":"https://www.academia.edu/Documents/in/Immunology?f_ri=14109","nofollow":false},{"id":3642,"name":"Stem Cells","url":"https://www.academia.edu/Documents/in/Stem_Cells?f_ri=14109","nofollow":false},{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=14109","nofollow":false},{"id":23323,"name":"Transcription Factors","url":"https://www.academia.edu/Documents/in/Transcription_Factors?f_ri=14109"},{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis?f_ri=14109"},{"id":50781,"name":"Haematology","url":"https://www.academia.edu/Documents/in/Haematology?f_ri=14109"},{"id":57808,"name":"Cell line","url":"https://www.academia.edu/Documents/in/Cell_line?f_ri=14109"},{"id":59057,"name":"Acute Myeloid Leukemia","url":"https://www.academia.edu/Documents/in/Acute_Myeloid_Leukemia?f_ri=14109"},{"id":100657,"name":"Therapy","url":"https://www.academia.edu/Documents/in/Therapy?f_ri=14109"},{"id":107235,"name":"C2H2 zinc fingers","url":"https://www.academia.edu/Documents/in/C2H2_zinc_fingers?f_ri=14109"},{"id":186941,"name":"Gene Duplication","url":"https://www.academia.edu/Documents/in/Gene_Duplication?f_ri=14109"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=14109"},{"id":489727,"name":"Prognosis","url":"https://www.academia.edu/Documents/in/Prognosis?f_ri=14109"},{"id":1186610,"name":"DNA binding proteins","url":"https://www.academia.edu/Documents/in/DNA_binding_proteins?f_ri=14109"},{"id":2685947,"name":"Proto-Oncogenes","url":"https://www.academia.edu/Documents/in/Proto-Oncogenes?f_ri=14109"}]}, }) } })();</script></ul></li></ul></div></div></div><div class="u-taCenter Pagination"><ul class="pagination"><li class="next_page"><a href="/Documents/in/Leukemia?after=50%2C32936482" rel="next">Next</a></li><li class="last next"><a href="/Documents/in/Leukemia?page=last">Last »</a></li></ul></div></div><div class="hidden-xs hidden-sm"><div class="u-pl6x"><div style="width: 300px;"><div class="panel panel-flat u-mt7x"><div class="panel-heading u-p5x"><div class="u-tcGrayDark u-taCenter u-fw700 u-textUppercase">Related Topics</div></div><ul class="list-group"><li class="list-group-item media_v2 u-mt0x u-p3x"><div class="media-body"><div class="u-tcGrayDarker u-fw700"><a class="u-tcGrayDarker" href="https://www.academia.edu/Documents/in/Glioblastoma_Multiforme">Glioblastoma Multiforme</a></div></div><div class="media-right media-middle"><a class="u-tcGreen u-textDecorationNone u-linkUnstyled u-fw500 hidden" data-follow-ri-id="463461">Follow</a><a class="u-tcGray u-textDecorationNone u-linkUnstyled u-fw500 hidden" data-unfollow-ri-id="463461">Following</a></div></li><li class="list-group-item media_v2 u-mt0x u-p3x"><div class="media-body"><div class="u-tcGrayDarker u-fw700"><a class="u-tcGrayDarker" href="https://www.academia.edu/Documents/in/Medicine_and_Health_Sciences">Medicine and Health Sciences</a></div></div><div class="media-right media-middle"><a class="u-tcGreen u-textDecorationNone u-linkUnstyled u-fw500 hidden" data-follow-ri-id="882996">Follow</a><a class="u-tcGray u-textDecorationNone u-linkUnstyled u-fw500 hidden" data-unfollow-ri-id="882996">Following</a></div></li><li class="list-group-item media_v2 u-mt0x u-p3x"><div class="media-body"><div class="u-tcGrayDarker u-fw700"><a class="u-tcGrayDarker" href="https://www.academia.edu/Documents/in/Hematopoietic_Stem_Cells">Hematopoietic Stem Cells</a></div></div><div class="media-right media-middle"><a class="u-tcGreen u-textDecorationNone u-linkUnstyled u-fw500 hidden" data-follow-ri-id="53113">Follow</a><a class="u-tcGray u-textDecorationNone u-linkUnstyled u-fw500 hidden" data-unfollow-ri-id="53113">Following</a></div></li><li class="list-group-item media_v2 u-mt0x u-p3x"><div class="media-body"><div class="u-tcGrayDarker u-fw700"><a class="u-tcGrayDarker" href="https://www.academia.edu/Documents/in/Brain_cancer">Brain cancer</a></div></div><div class="media-right media-middle"><a class="u-tcGreen u-textDecorationNone u-linkUnstyled u-fw500 hidden" data-follow-ri-id="23165">Follow</a><a class="u-tcGray u-textDecorationNone u-linkUnstyled u-fw500 hidden" data-unfollow-ri-id="23165">Following</a></div></li><li class="list-group-item media_v2 u-mt0x u-p3x"><div class="media-body"><div class="u-tcGrayDarker u-fw700"><a class="u-tcGrayDarker" href="https://www.academia.edu/Documents/in/Cell_and_Molecular_Biology">Cell and Molecular Biology</a></div></div><div class="media-right media-middle"><a class="u-tcGreen u-textDecorationNone u-linkUnstyled u-fw500 hidden" data-follow-ri-id="46578">Follow</a><a class="u-tcGray u-textDecorationNone u-linkUnstyled u-fw500 hidden" data-unfollow-ri-id="46578">Following</a></div></li><li class="list-group-item media_v2 u-mt0x u-p3x"><div class="media-body"><div class="u-tcGrayDarker u-fw700"><a class="u-tcGrayDarker" href="https://www.academia.edu/Documents/in/Hematology">Hematology</a></div></div><div class="media-right media-middle"><a class="u-tcGreen u-textDecorationNone u-linkUnstyled u-fw500 hidden" data-follow-ri-id="619">Follow</a><a class="u-tcGray u-textDecorationNone u-linkUnstyled u-fw500 hidden" data-unfollow-ri-id="619">Following</a></div></li><li class="list-group-item media_v2 u-mt0x u-p3x"><div class="media-body"><div class="u-tcGrayDarker u-fw700"><a class="u-tcGrayDarker" href="https://www.academia.edu/Documents/in/Lymphoma">Lymphoma</a></div></div><div class="media-right media-middle"><a class="u-tcGreen u-textDecorationNone u-linkUnstyled u-fw500 hidden" data-follow-ri-id="55269">Follow</a><a class="u-tcGray u-textDecorationNone u-linkUnstyled u-fw500 hidden" data-unfollow-ri-id="55269">Following</a></div></li><li class="list-group-item media_v2 u-mt0x u-p3x"><div class="media-body"><div class="u-tcGrayDarker u-fw700"><a class="u-tcGrayDarker" href="https://www.academia.edu/Documents/in/MicroRNA">MicroRNA</a></div></div><div class="media-right media-middle"><a class="u-tcGreen u-textDecorationNone u-linkUnstyled u-fw500 hidden" data-follow-ri-id="5490">Follow</a><a class="u-tcGray u-textDecorationNone u-linkUnstyled u-fw500 hidden" data-unfollow-ri-id="5490">Following</a></div></li><li class="list-group-item media_v2 u-mt0x u-p3x"><div class="media-body"><div class="u-tcGrayDarker u-fw700"><a class="u-tcGrayDarker" href="https://www.academia.edu/Documents/in/Molecular_Biology_Cancer">Molecular Biology Cancer</a></div></div><div class="media-right media-middle"><a class="u-tcGreen u-textDecorationNone u-linkUnstyled u-fw500 hidden" data-follow-ri-id="46992">Follow</a><a class="u-tcGray u-textDecorationNone u-linkUnstyled u-fw500 hidden" data-unfollow-ri-id="46992">Following</a></div></li><li class="list-group-item media_v2 u-mt0x u-p3x"><div class="media-body"><div class="u-tcGrayDarker u-fw700"><a class="u-tcGrayDarker" href="https://www.academia.edu/Documents/in/Cancer_stem_cells">Cancer stem cells</a></div></div><div class="media-right media-middle"><a class="u-tcGreen u-textDecorationNone u-linkUnstyled u-fw500 hidden" data-follow-ri-id="10027">Follow</a><a class="u-tcGray u-textDecorationNone u-linkUnstyled u-fw500 hidden" data-unfollow-ri-id="10027">Following</a></div></li></ul></div></div></div></div></div></div><script>// MIT License // Copyright © 2011 Sebastian Tschan, https://blueimp.net // Permission is hereby granted, free of charge, to any person obtaining a copy of // this software and associated documentation files (the "Software"), to deal in // the Software without restriction, including without limitation the rights to // use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of // the Software, and to permit persons to whom the Software is furnished to do so, // subject to the following conditions: // The above copyright notice and this permission notice shall be included in all // copies or substantial portions of the Software. // THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR // IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS // FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR // COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER // IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN // CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. !function(n){"use strict";function d(n,t){var r=(65535&n)+(65535&t);return(n>>16)+(t>>16)+(r>>16)<<16|65535&r}function f(n,t,r,e,o,u){return d((c=d(d(t,n),d(e,u)))<<(f=o)|c>>>32-f,r);var c,f}function l(n,t,r,e,o,u,c){return f(t&r|~t&e,n,t,o,u,c)}function v(n,t,r,e,o,u,c){return f(t&e|r&~e,n,t,o,u,c)}function g(n,t,r,e,o,u,c){return f(t^r^e,n,t,o,u,c)}function m(n,t,r,e,o,u,c){return f(r^(t|~e),n,t,o,u,c)}function i(n,t){var r,e,o,u;n[t>>5]|=128<<t%32,n[14+(t+64>>>9<<4)]=t;for(var c=1732584193,f=-271733879,i=-1732584194,a=271733878,h=0;h<n.length;h+=16)c=l(r=c,e=f,o=i,u=a,n[h],7,-680876936),a=l(a,c,f,i,n[h+1],12,-389564586),i=l(i,a,c,f,n[h+2],17,606105819),f=l(f,i,a,c,n[h+3],22,-1044525330),c=l(c,f,i,a,n[h+4],7,-176418897),a=l(a,c,f,i,n[h+5],12,1200080426),i=l(i,a,c,f,n[h+6],17,-1473231341),f=l(f,i,a,c,n[h+7],22,-45705983),c=l(c,f,i,a,n[h+8],7,1770035416),a=l(a,c,f,i,n[h+9],12,-1958414417),i=l(i,a,c,f,n[h+10],17,-42063),f=l(f,i,a,c,n[h+11],22,-1990404162),c=l(c,f,i,a,n[h+12],7,1804603682),a=l(a,c,f,i,n[h+13],12,-40341101),i=l(i,a,c,f,n[h+14],17,-1502002290),c=v(c,f=l(f,i,a,c,n[h+15],22,1236535329),i,a,n[h+1],5,-165796510),a=v(a,c,f,i,n[h+6],9,-1069501632),i=v(i,a,c,f,n[h+11],14,643717713),f=v(f,i,a,c,n[h],20,-373897302),c=v(c,f,i,a,n[h+5],5,-701558691),a=v(a,c,f,i,n[h+10],9,38016083),i=v(i,a,c,f,n[h+15],14,-660478335),f=v(f,i,a,c,n[h+4],20,-405537848),c=v(c,f,i,a,n[h+9],5,568446438),a=v(a,c,f,i,n[h+14],9,-1019803690),i=v(i,a,c,f,n[h+3],14,-187363961),f=v(f,i,a,c,n[h+8],20,1163531501),c=v(c,f,i,a,n[h+13],5,-1444681467),a=v(a,c,f,i,n[h+2],9,-51403784),i=v(i,a,c,f,n[h+7],14,1735328473),c=g(c,f=v(f,i,a,c,n[h+12],20,-1926607734),i,a,n[h+5],4,-378558),a=g(a,c,f,i,n[h+8],11,-2022574463),i=g(i,a,c,f,n[h+11],16,1839030562),f=g(f,i,a,c,n[h+14],23,-35309556),c=g(c,f,i,a,n[h+1],4,-1530992060),a=g(a,c,f,i,n[h+4],11,1272893353),i=g(i,a,c,f,n[h+7],16,-155497632),f=g(f,i,a,c,n[h+10],23,-1094730640),c=g(c,f,i,a,n[h+13],4,681279174),a=g(a,c,f,i,n[h],11,-358537222),i=g(i,a,c,f,n[h+3],16,-722521979),f=g(f,i,a,c,n[h+6],23,76029189),c=g(c,f,i,a,n[h+9],4,-640364487),a=g(a,c,f,i,n[h+12],11,-421815835),i=g(i,a,c,f,n[h+15],16,530742520),c=m(c,f=g(f,i,a,c,n[h+2],23,-995338651),i,a,n[h],6,-198630844),a=m(a,c,f,i,n[h+7],10,1126891415),i=m(i,a,c,f,n[h+14],15,-1416354905),f=m(f,i,a,c,n[h+5],21,-57434055),c=m(c,f,i,a,n[h+12],6,1700485571),a=m(a,c,f,i,n[h+3],10,-1894986606),i=m(i,a,c,f,n[h+10],15,-1051523),f=m(f,i,a,c,n[h+1],21,-2054922799),c=m(c,f,i,a,n[h+8],6,1873313359),a=m(a,c,f,i,n[h+15],10,-30611744),i=m(i,a,c,f,n[h+6],15,-1560198380),f=m(f,i,a,c,n[h+13],21,1309151649),c=m(c,f,i,a,n[h+4],6,-145523070),a=m(a,c,f,i,n[h+11],10,-1120210379),i=m(i,a,c,f,n[h+2],15,718787259),f=m(f,i,a,c,n[h+9],21,-343485551),c=d(c,r),f=d(f,e),i=d(i,o),a=d(a,u);return[c,f,i,a]}function a(n){for(var t="",r=32*n.length,e=0;e<r;e+=8)t+=String.fromCharCode(n[e>>5]>>>e%32&255);return t}function h(n){var t=[];for(t[(n.length>>2)-1]=void 0,e=0;e<t.length;e+=1)t[e]=0;for(var r=8*n.length,e=0;e<r;e+=8)t[e>>5]|=(255&n.charCodeAt(e/8))<<e%32;return t}function e(n){for(var t,r="0123456789abcdef",e="",o=0;o<n.length;o+=1)t=n.charCodeAt(o),e+=r.charAt(t>>>4&15)+r.charAt(15&t);return e}function r(n){return unescape(encodeURIComponent(n))}function o(n){return a(i(h(t=r(n)),8*t.length));var t}function u(n,t){return function(n,t){var r,e,o=h(n),u=[],c=[];for(u[15]=c[15]=void 0,16<o.length&&(o=i(o,8*n.length)),r=0;r<16;r+=1)u[r]=909522486^o[r],c[r]=1549556828^o[r];return e=i(u.concat(h(t)),512+8*t.length),a(i(c.concat(e),640))}(r(n),r(t))}function t(n,t,r){return t?r?u(t,n):e(u(t,n)):r?o(n):e(o(n))}"function"==typeof define&&define.amd?define(function(){return t}):"object"==typeof module&&module.exports?module.exports=t:n.md5=t}(this);</script><script>window.AbTest = (function() { return { 'ab_test': (uniqueId, test_name, buckets) => { let override = new URLSearchParams(window.location.search).get(`ab_test[${test_name}]`); if ( override ) { return override; } const bucketNames = buckets.map((bucket) => { return typeof bucket === 'string' ? bucket : Object.keys(bucket)[0]; }); const weights = buckets.map((bucket) => { return typeof bucket === 'string' ? 1 : Object.values(bucket)[0]; }); const total = weights.reduce((sum, weight) => sum + weight); const hash = md5(`${uniqueId}${test_name}`); const hashNum = parseInt(hash.slice(-12), 16); let bucketPoint = total * (hashNum % 100000) / 100000; const bucket = bucketNames.find((_, i) => { if (weights[i] > bucketPoint) { return true; } bucketPoint -= weights[i]; return false; }); return bucket; } }; })();</script><div data-auto_select="false" data-client_id="331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b" data-landing_url="https://www.academia.edu/Documents/in/Leukemia" data-login_uri="https://www.academia.edu/registrations/google_one_tap" data-moment_callback="onGoogleOneTapEvent" id="g_id_onload"></div><script>function onGoogleOneTapEvent(event) { var momentType = event.getMomentType(); var momentReason = null; if (event.isNotDisplayed()) { momentReason = event.getNotDisplayedReason(); } else if (event.isSkippedMoment()) { momentReason = event.getSkippedReason(); } else if (event.isDismissedMoment()) { momentReason = event.getDismissedReason(); } Aedu.arbitraryEvents.write('GoogleOneTapEvent', { moment_type: momentType, moment_reason: momentReason, }); }</script><script>(function() { var auvid = unescape( document.cookie .split(/; ?/) .find((s) => s.startsWith('auvid')) .substring(6)); var bucket = AbTest.ab_test(auvid, 'lo_ri_one_tap_google_sign_on', ['control', 'one_tap_google_sign_on']); if (bucket === 'control') return; var oneTapTag = document.createElement('script') oneTapTag.async = true oneTapTag.defer = true oneTapTag.src = 'https://accounts.google.com/gsi/client' document.body.appendChild(oneTapTag) })();</script></div></div></div> </div> <div class="bootstrap login"><div class="modal fade login-modal" id="login-modal"><div class="login-modal-dialog modal-dialog"><div class="modal-content"><div class="modal-header"><button class="close close" data-dismiss="modal" type="button"><span aria-hidden="true">×</span><span class="sr-only">Close</span></button><h4 class="modal-title text-center"><strong>Log In</strong></h4></div><div class="modal-body"><div class="row"><div class="col-xs-10 col-xs-offset-1"><button class="btn btn-fb btn-lg btn-block btn-v-center-content" id="login-facebook-oauth-button"><svg style="float: left; width: 19px; line-height: 1em; margin-right: .3em;" aria-hidden="true" focusable="false" data-prefix="fab" data-icon="facebook-square" class="svg-inline--fa fa-facebook-square fa-w-14" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 448 512"><path fill="currentColor" d="M400 32H48A48 48 0 0 0 0 80v352a48 48 0 0 0 48 48h137.25V327.69h-63V256h63v-54.64c0-62.15 37-96.48 93.67-96.48 27.14 0 55.52 4.84 55.52 4.84v61h-31.27c-30.81 0-40.42 19.12-40.42 38.73V256h68.78l-11 71.69h-57.78V480H400a48 48 0 0 0 48-48V80a48 48 0 0 0-48-48z"></path></svg><small><strong>Log in</strong> with <strong>Facebook</strong></small></button><br /><button class="btn btn-google btn-lg btn-block btn-v-center-content" id="login-google-oauth-button"><svg style="float: left; width: 22px; line-height: 1em; margin-right: .3em;" aria-hidden="true" focusable="false" data-prefix="fab" data-icon="google-plus" class="svg-inline--fa fa-google-plus fa-w-16" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M256,8C119.1,8,8,119.1,8,256S119.1,504,256,504,504,392.9,504,256,392.9,8,256,8ZM185.3,380a124,124,0,0,1,0-248c31.3,0,60.1,11,83,32.3l-33.6,32.6c-13.2-12.9-31.3-19.1-49.4-19.1-42.9,0-77.2,35.5-77.2,78.1S142.3,334,185.3,334c32.6,0,64.9-19.1,70.1-53.3H185.3V238.1H302.2a109.2,109.2,0,0,1,1.9,20.7c0,70.8-47.5,121.2-118.8,121.2ZM415.5,273.8v35.5H380V273.8H344.5V238.3H380V202.8h35.5v35.5h35.2v35.5Z"></path></svg><small><strong>Log in</strong> with <strong>Google</strong></small></button><br /><style type="text/css">.sign-in-with-apple-button { width: 100%; height: 52px; border-radius: 3px; border: 1px solid black; cursor: pointer; }</style><script src="https://appleid.cdn-apple.com/appleauth/static/jsapi/appleid/1/en_US/appleid.auth.js" type="text/javascript"></script><div class="sign-in-with-apple-button" data-border="false" data-color="white" id="appleid-signin"><span   ="Sign Up with Apple" class="u-fs11"></span></div><script>AppleID.auth.init({ clientId: 'edu.academia.applesignon', scope: 'name email', redirectURI: 'https://www.academia.edu/sessions', state: "61f152d5ff098f964f41ba403396401508c23ff570a1faa23201c115e7b617fa", });</script><script>// Hacky way of checking if on fast loswp if (window.loswp == null) { (function() { const Google = window?.Aedu?.Auth?.OauthButton?.Login?.Google; const Facebook = window?.Aedu?.Auth?.OauthButton?.Login?.Facebook; if (Google) { new Google({ el: '#login-google-oauth-button', rememberMeCheckboxId: 'remember_me', track: null }); } if (Facebook) { new Facebook({ el: '#login-facebook-oauth-button', rememberMeCheckboxId: 'remember_me', track: null }); } })(); }</script></div></div></div><div class="modal-body"><div class="row"><div class="col-xs-10 col-xs-offset-1"><div class="hr-heading login-hr-heading"><span class="hr-heading-text">or</span></div></div></div></div><div class="modal-body"><div class="row"><div class="col-xs-10 col-xs-offset-1"><form class="js-login-form" action="https://www.academia.edu/sessions" accept-charset="UTF-8" method="post"><input name="utf8" type="hidden" value="✓" autocomplete="off" /><input type="hidden" name="authenticity_token" value="8nvrRniojwb/WHlDQSD3dzevC+/DbTeA8F2Qv1qcJ2+/ZZwzJe6mSiIReK0iNDjvHu2asiuy2Q5AY/A+mccCQQ==" autocomplete="off" /><div class="form-group"><label class="control-label" for="login-modal-email-input" style="font-size: 14px;">Email</label><input class="form-control" id="login-modal-email-input" name="login" type="email" /></div><div class="form-group"><label class="control-label" for="login-modal-password-input" style="font-size: 14px;">Password</label><input class="form-control" id="login-modal-password-input" name="password" type="password" /></div><input type="hidden" name="post_login_redirect_url" id="post_login_redirect_url" value="https://www.academia.edu/Documents/in/Leukemia" autocomplete="off" /><div class="checkbox"><label><input type="checkbox" name="remember_me" id="remember_me" value="1" checked="checked" /><small style="font-size: 12px; margin-top: 2px; display: inline-block;">Remember me on this computer</small></label></div><br><input type="submit" name="commit" value="Log In" class="btn btn-primary btn-block btn-lg js-login-submit" data-disable-with="Log In" /></br></form><script>typeof window?.Aedu?.recaptchaManagedForm === 'function' && window.Aedu.recaptchaManagedForm( document.querySelector('.js-login-form'), document.querySelector('.js-login-submit') );</script><small style="font-size: 12px;"><br />or <a data-target="#login-modal-reset-password-container" data-toggle="collapse" href="javascript:void(0)">reset password</a></small><div class="collapse" id="login-modal-reset-password-container"><br /><div class="well margin-0x"><form class="js-password-reset-form" action="https://www.academia.edu/reset_password" accept-charset="UTF-8" method="post"><input name="utf8" type="hidden" value="✓" autocomplete="off" /><input type="hidden" name="authenticity_token" value="UV7RI+gsexIDWtCmCMCmsIHl/niwU+E0XePozorfUqkcQKZWtWpSXt4T0Uhr1GkoqKdvJViMD7rt3YhPSYR3hw==" autocomplete="off" /><p>Enter the email address you signed up with and we'll email you a reset link.</p><div class="form-group"><input class="form-control" name="email" type="email" /></div><script src="https://recaptcha.net/recaptcha/api.js" async defer></script> <script> var invisibleRecaptchaSubmit = function () { var closestForm = function (ele) { var curEle = ele.parentNode; while (curEle.nodeName !== 'FORM' && curEle.nodeName !== 'BODY'){ curEle = curEle.parentNode; } return curEle.nodeName === 'FORM' ? curEle : null }; var eles = document.getElementsByClassName('g-recaptcha'); if (eles.length > 0) { var form = closestForm(eles[0]); if (form) { form.submit(); } } }; </script> <input type="submit" data-sitekey="6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj" data-callback="invisibleRecaptchaSubmit" class="g-recaptcha btn btn-primary btn-block" value="Email me a link" value=""/> </form></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/collapse-45805421cf446ca5adf7aaa1935b08a3a8d1d9a6cc5d91a62a2a3a00b20b3e6a.js"], function() { // from javascript_helper.rb $("#login-modal-reset-password-container").on("shown.bs.collapse", function() { $(this).find("input[type=email]").focus(); }); }); </script> </div></div></div><div class="modal-footer"><div class="text-center"><small style="font-size: 12px;">Need an account? <a rel="nofollow" href="https://www.academia.edu/signup">Click here to sign up</a></small></div></div></div></div></div></div><script>// If we are on subdomain or non-bootstrapped page, redirect to login page instead of showing modal (function(){ if (typeof $ === 'undefined') return; var host = window.location.hostname; if ((host === $domain || host === "www."+$domain) && (typeof $().modal === 'function')) { $("#nav_log_in").click(function(e) { // Don't follow the link and open the modal e.preventDefault(); $("#login-modal").on('shown.bs.modal', function() { $(this).find("#login-modal-email-input").focus() }).modal('show'); }); } })()</script> <div class="bootstrap" id="footer"><div class="footer-content clearfix text-center padding-top-7x" style="width:100%;"><ul class="footer-links-secondary footer-links-wide list-inline margin-bottom-1x"><li><a href="https://www.academia.edu/about">About</a></li><li><a href="https://www.academia.edu/press">Press</a></li><li><a rel="nofollow" href="https://medium.com/academia">Blog</a></li><li><a href="https://www.academia.edu/documents">Papers</a></li><li><a href="https://www.academia.edu/topics">Topics</a></li><li><a href="https://www.academia.edu/journals">Academia.edu Journals</a></li><li><a rel="nofollow" href="https://www.academia.edu/hiring"><svg style="width: 13px; height: 13px;" aria-hidden="true" focusable="false" data-prefix="fas" data-icon="briefcase" class="svg-inline--fa fa-briefcase fa-w-16" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M320 336c0 8.84-7.16 16-16 16h-96c-8.84 0-16-7.16-16-16v-48H0v144c0 25.6 22.4 48 48 48h416c25.6 0 48-22.4 48-48V288H320v48zm144-208h-80V80c0-25.6-22.4-48-48-48H176c-25.6 0-48 22.4-48 48v48H48c-25.6 0-48 22.4-48 48v80h512v-80c0-25.6-22.4-48-48-48zm-144 0H192V96h128v32z"></path></svg> <strong>We're Hiring!</strong></a></li><li><a rel="nofollow" href="https://support.academia.edu/"><svg style="width: 12px; height: 12px;" aria-hidden="true" focusable="false" data-prefix="fas" data-icon="question-circle" class="svg-inline--fa fa-question-circle fa-w-16" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M504 256c0 136.997-111.043 248-248 248S8 392.997 8 256C8 119.083 119.043 8 256 8s248 111.083 248 248zM262.655 90c-54.497 0-89.255 22.957-116.549 63.758-3.536 5.286-2.353 12.415 2.715 16.258l34.699 26.31c5.205 3.947 12.621 3.008 16.665-2.122 17.864-22.658 30.113-35.797 57.303-35.797 20.429 0 45.698 13.148 45.698 32.958 0 14.976-12.363 22.667-32.534 33.976C247.128 238.528 216 254.941 216 296v4c0 6.627 5.373 12 12 12h56c6.627 0 12-5.373 12-12v-1.333c0-28.462 83.186-29.647 83.186-106.667 0-58.002-60.165-102-116.531-102zM256 338c-25.365 0-46 20.635-46 46 0 25.364 20.635 46 46 46s46-20.636 46-46c0-25.365-20.635-46-46-46z"></path></svg> <strong>Help Center</strong></a></li></ul><ul class="footer-links-tertiary list-inline margin-bottom-1x"><li class="small">Find new research papers in:</li><li class="small"><a href="https://www.academia.edu/Documents/in/Physics">Physics</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Chemistry">Chemistry</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Biology">Biology</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Health_Sciences">Health Sciences</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Ecology">Ecology</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Earth_Sciences">Earth Sciences</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Cognitive_Science">Cognitive Science</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Mathematics">Mathematics</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Computer_Science">Computer Science</a></li></ul></div></div><div class="DesignSystem" id="credit" style="width:100%;"><ul class="u-pl0x footer-links-legal list-inline"><li><a rel="nofollow" href="https://www.academia.edu/terms">Terms</a></li><li><a rel="nofollow" href="https://www.academia.edu/privacy">Privacy</a></li><li><a rel="nofollow" href="https://www.academia.edu/copyright">Copyright</a></li><li>Academia ©2024</li></ul></div><script> //<![CDATA[ window.detect_gmtoffset = true; window.Academia && window.Academia.set_gmtoffset && Academia.set_gmtoffset('/gmtoffset'); //]]> </script> <div id='overlay_background'></div> <div id='bootstrap-modal-container' class='bootstrap'></div> <div id='ds-modal-container' class='bootstrap DesignSystem'></div> <div id='full-screen-modal'></div> </div> </body> </html>