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overflow: hidden; text-overflow: ellipsis; -webkit-line-clamp: 3; -webkit-box-orient: vertical; }</style><div class="col-xs-12 clearfix"><div class="u-floatLeft"><h1 class="PageHeader-title u-m0x u-fs30">Prospective studies</h1><div class="u-tcGrayDark">29,590 Followers</div><div class="u-tcGrayDark u-mt2x">Recent papers in <b>Prospective studies</b></div></div></div></div></div></div><div class="TabbedNavigation"><div class="container"><div class="row"><div class="col-xs-12 clearfix"><ul class="nav u-m0x u-p0x list-inline u-displayFlex"><li class="active"><a href="https://www.academia.edu/Documents/in/Prospective_studies">Top Papers</a></li><li><a href="https://www.academia.edu/Documents/in/Prospective_studies/MostCited">Most Cited Papers</a></li><li><a href="https://www.academia.edu/Documents/in/Prospective_studies/MostDownloaded">Most Downloaded Papers</a></li><li><a href="https://www.academia.edu/Documents/in/Prospective_studies/MostRecent">Newest Papers</a></li><li><a class="" href="https://www.academia.edu/People/Prospective_studies">People</a></li></ul></div><style type="text/css">ul.nav{flex-direction:row}@media(max-width: 567px){ul.nav{flex-direction:column}.TabbedNavigation li{max-width:100%}.TabbedNavigation li.active{background-color:var(--background-grey, #dddde2)}.TabbedNavigation li.active:before,.TabbedNavigation li.active:after{display:none}}</style></div></div></div><div class="container"><div class="row"><div class="col-xs-12"><div class="u-displayFlex"><div class="u-flexGrow1"><div class="works"><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_23243348" data-work_id="23243348" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/23243348/Effect_of_oxygen_concentration_on_human_in_vitro_fertilization_and_embryo_culture">Effect of oxygen concentration on human in-vitro fertilization and embryo culture</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">In this prospective randomized study on 1380 consecutive in-vitro fertilization (IVF) treatments, the results were compared of culture of human oocytes and embryos for the first 2 or 3 days of development in microdroplets of medium under... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_23243348" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">In this prospective randomized study on 1380 consecutive in-vitro fertilization (IVF) treatments, the results were compared of culture of human oocytes and embryos for the first 2 or 3 days of development in microdroplets of medium under oil using a gas phase containing either atmospheric (~20%) or reduced (5%) O 2 concentrations. No significant differences were found between the two groups cultured under either 5% or 20% O 2 in rates of fertilization (60 versus 61%, respectively), embryo development at day 2 or 3, pregnancy (26.6 versus 25.4%, respectively), and implantation (13.4 versus 14.0%, respectively). Culture of surplus embryos under 5% O 2 resulted in a significantly higher mean incidence of blastocyst formation per cycle as compared to the 20% O 2 group (25.8 ⍨ 2.0 versus 20.4 ⍨ 1.9, respectively). The mean number of cells of embryos classified as blastocysts by microscopic observation of a blastocoel was significantly higher in the 5% O 2 group as compared to the 20% O 2 group, both in blastocysts fixed on day 5 (39.8 ⍨ 1.7 versus 31.9 ⍨ 1.9, respectively), as well as those fixed on day 6 (45.6 ⍨ 2.6 versus 33.7 ⍨ 3.4, respectively). This difference was due to the fact that significantly more blastocysts of the 20% O 2 group had an abnormal low cell number of < 25 as compared to the 5% O 2 group, both in blastocysts fixed on day 5 (39 versus 22%, respectively), as well as those fixed on day 6 (43 versus 22%, respectively). To conclude, although culture under 5% O 2 leads to slightly improved preimplantation embryonic viability, this effect is either too marginal to result in higher pregnancy rates, or low O 2 concentrations exert an effect during the later stages of preimplantation development only.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/23243348" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="2b284adf9a214e453e7358deb5dadc5e" rel="nofollow" data-download="{"attachment_id":43726188,"asset_id":23243348,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/43726188/download_file?st=MTczOTgwMzc0NSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="45104820" href="https://independent.academia.edu/JDumoulin">John Dumoulin</a><script data-card-contents-for-user="45104820" type="text/json">{"id":45104820,"first_name":"John","last_name":"Dumoulin","domain_name":"independent","page_name":"JDumoulin","display_name":"John Dumoulin","profile_url":"https://independent.academia.edu/JDumoulin?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_23243348 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="23243348"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 23243348, container: ".js-paper-rank-work_23243348", }); });</script></li><li class="js-percentile-work_23243348 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 23243348; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_23243348"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_23243348 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="23243348"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 23243348; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=23243348]").text(description); $(".js-view-count-work_23243348").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_23243348").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="23243348"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">11</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="41720" rel="nofollow" href="https://www.academia.edu/Documents/in/Human">Human</a>, <script data-card-contents-for-ri="41720" type="text/json">{"id":41720,"name":"Human","url":"https://www.academia.edu/Documents/in/Human?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a>, <script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62550" rel="nofollow" href="https://www.academia.edu/Documents/in/Pregnancy">Pregnancy</a>, <script data-card-contents-for-ri="62550" type="text/json">{"id":62550,"name":"Pregnancy","url":"https://www.academia.edu/Documents/in/Pregnancy?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="105108" rel="nofollow" href="https://www.academia.edu/Documents/in/In_Vitro_Fertilization">In Vitro Fertilization</a><script data-card-contents-for-ri="105108" type="text/json">{"id":105108,"name":"In Vitro Fertilization","url":"https://www.academia.edu/Documents/in/In_Vitro_Fertilization?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=23243348]'), work: {"id":23243348,"title":"Effect of oxygen concentration on human in-vitro fertilization and embryo culture","created_at":"2016-03-14T13:42:31.444-07:00","url":"https://www.academia.edu/23243348/Effect_of_oxygen_concentration_on_human_in_vitro_fertilization_and_embryo_culture?f_ri=62112","dom_id":"work_23243348","summary":"In this prospective randomized study on 1380 consecutive in-vitro fertilization (IVF) treatments, the results were compared of culture of human oocytes and embryos for the first 2 or 3 days of development in microdroplets of medium under oil using a gas phase containing either atmospheric (~20%) or reduced (5%) O 2 concentrations. No significant differences were found between the two groups cultured under either 5% or 20% O 2 in rates of fertilization (60 versus 61%, respectively), embryo development at day 2 or 3, pregnancy (26.6 versus 25.4%, respectively), and implantation (13.4 versus 14.0%, respectively). Culture of surplus embryos under 5% O 2 resulted in a significantly higher mean incidence of blastocyst formation per cycle as compared to the 20% O 2 group (25.8 ⍨ 2.0 versus 20.4 ⍨ 1.9, respectively). The mean number of cells of embryos classified as blastocysts by microscopic observation of a blastocoel was significantly higher in the 5% O 2 group as compared to the 20% O 2 group, both in blastocysts fixed on day 5 (39.8 ⍨ 1.7 versus 31.9 ⍨ 1.9, respectively), as well as those fixed on day 6 (45.6 ⍨ 2.6 versus 33.7 ⍨ 3.4, respectively). This difference was due to the fact that significantly more blastocysts of the 20% O 2 group had an abnormal low cell number of \u003c 25 as compared to the 5% O 2 group, both in blastocysts fixed on day 5 (39 versus 22%, respectively), as well as those fixed on day 6 (43 versus 22%, respectively). To conclude, although culture under 5% O 2 leads to slightly improved preimplantation embryonic viability, this effect is either too marginal to result in higher pregnancy rates, or low O 2 concentrations exert an effect during the later stages of preimplantation development only.","downloadable_attachments":[{"id":43726188,"asset_id":23243348,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":45104820,"first_name":"John","last_name":"Dumoulin","domain_name":"independent","page_name":"JDumoulin","display_name":"John Dumoulin","profile_url":"https://independent.academia.edu/JDumoulin?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":41720,"name":"Human","url":"https://www.academia.edu/Documents/in/Human?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":62550,"name":"Pregnancy","url":"https://www.academia.edu/Documents/in/Pregnancy?f_ri=62112","nofollow":true},{"id":105108,"name":"In Vitro Fertilization","url":"https://www.academia.edu/Documents/in/In_Vitro_Fertilization?f_ri=62112","nofollow":true},{"id":348029,"name":"Fertilization","url":"https://www.academia.edu/Documents/in/Fertilization?f_ri=62112"},{"id":351108,"name":"Human reproduction","url":"https://www.academia.edu/Documents/in/Human_reproduction?f_ri=62112"},{"id":380825,"name":"Oxygen","url":"https://www.academia.edu/Documents/in/Oxygen?f_ri=62112"},{"id":613442,"name":"Fertilization in Vitro","url":"https://www.academia.edu/Documents/in/Fertilization_in_Vitro?f_ri=62112"},{"id":1027717,"name":"Embryos","url":"https://www.academia.edu/Documents/in/Embryos?f_ri=62112"},{"id":1278603,"name":"Pregnancy Rate","url":"https://www.academia.edu/Documents/in/Pregnancy_Rate?f_ri=62112"},{"id":1838309,"name":"Embryo Development","url":"https://www.academia.edu/Documents/in/Embryo_Development?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_27984081 coauthored" data-work_id="27984081" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/27984081/The_Dog_as_an_Animal_Model_for_Intervertebral_Disc_Degeneration">The Dog as an Animal Model for Intervertebral Disc Degeneration?</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Study Design. Prospective observational and analytic study. Objective. To investigate whether spontaneous intervertebral disc degeneration (IVDD) occurring in both chondrodystrophic (CD) and nonchondrodystrophic dogs (NCD) can be used as... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_27984081" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Study Design. Prospective observational and analytic study. Objective. To investigate whether spontaneous intervertebral disc degeneration (IVDD) occurring in both chondrodystrophic (CD) and nonchondrodystrophic dogs (NCD) can be used as a valid translational model for human IVDD research. Summary of Background Data. Different animal models are used in IVDD research, but in most of these models IVDD is induced manually or chemically rather than occurring spontaneously. Methods. A total of 184 intervertebral discs (IVDs) from 19 dogs of different breeds were used. The extent of IVDD was evaluated by macroscopic grading, histopathology, glycosaminoglycan content, and matrix metalloproteinase 2 activity. Canine data were compared with human IVD data acquired in this study or from the literature. Results. Gross pathology of IVDD in both dog types (CD and NCD) and humans showed many similarities, but the cartilaginous endplates were signifi cantly thicker and the subchondral cortices signifi cantly thinner in humans than in dogs. Notochordal cells were still present in the IVDs of adult NCD but were not seen in the CD breeds or in humans. Signs of degeneration were seen in young dogs of CD breeds ( < 1 year of age), whereas this was only seen in older dogs of NCD breeds (5-7 years of age). The relative glycosaminoglycan content and metalloproteinase 2 activity in canine IVDD were similar to those in humans: metalloproteinase 2 activity increased and glycosaminoglycan content decreased with increasing severity of IVDD. Conclusion. IVDD is similar in humans and dogs. Both CD and NCD breeds may therefore serve as models of spontaneous IVDD for human research. However, as with all animal models, it is important to recognize interspecies differences and, indeed, the intraspecies differences between CD and NCD breeds (early vs. late onset of IVDD, respectively) to develop an optimal canine model of human IVDD.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/27984081" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="eeff9469bc98a9af960059c57e6817f6" rel="nofollow" data-download="{"attachment_id":48286519,"asset_id":27984081,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48286519/download_file?st=MTczOTgwMzc0NSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33399028" href="https://independent.academia.edu/NiklasBergknut">Niklas Bergknut</a><script data-card-contents-for-user="33399028" type="text/json">{"id":33399028,"first_name":"Niklas","last_name":"Bergknut","domain_name":"independent","page_name":"NiklasBergknut","display_name":"Niklas Bergknut","profile_url":"https://independent.academia.edu/NiklasBergknut?f_ri=62112","photo":"https://0.academia-photos.com/33399028/13905881/14972206/s65_niklas.bergknut.jpg"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-27984081">+2</span><div class="hidden js-additional-users-27984081"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/AnneSofieLagerstedt">Anne-Sofie Lagerstedt</a></span></div><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://uu.academia.edu/Bj%C3%B6rnMeij">Björn Meij</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-27984081'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-27984081').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_27984081 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="27984081"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 27984081, container: ".js-paper-rank-work_27984081", }); });</script></li><li class="js-percentile-work_27984081 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 27984081; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_27984081"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_27984081 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="27984081"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 27984081; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=27984081]").text(description); $(".js-view-count-work_27984081").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_27984081").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="27984081"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="1131" rel="nofollow" href="https://www.academia.edu/Documents/in/Biomedical_Engineering">Biomedical Engineering</a>, <script data-card-contents-for-ri="1131" type="text/json">{"id":1131,"name":"Biomedical Engineering","url":"https://www.academia.edu/Documents/in/Biomedical_Engineering?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4933" rel="nofollow" href="https://www.academia.edu/Documents/in/Spine">Spine</a>, <script data-card-contents-for-ri="4933" type="text/json">{"id":4933,"name":"Spine","url":"https://www.academia.edu/Documents/in/Spine?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6791" rel="nofollow" href="https://www.academia.edu/Documents/in/Aging">Aging</a>, <script data-card-contents-for-ri="6791" type="text/json">{"id":6791,"name":"Aging","url":"https://www.academia.edu/Documents/in/Aging?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="52438" rel="nofollow" href="https://www.academia.edu/Documents/in/Dogs">Dogs</a><script data-card-contents-for-ri="52438" type="text/json">{"id":52438,"name":"Dogs","url":"https://www.academia.edu/Documents/in/Dogs?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=27984081]'), work: {"id":27984081,"title":"The Dog as an Animal Model for Intervertebral Disc Degeneration?","created_at":"2016-08-24T10:04:32.037-07:00","url":"https://www.academia.edu/27984081/The_Dog_as_an_Animal_Model_for_Intervertebral_Disc_Degeneration?f_ri=62112","dom_id":"work_27984081","summary":"Study Design. Prospective observational and analytic study. Objective. To investigate whether spontaneous intervertebral disc degeneration (IVDD) occurring in both chondrodystrophic (CD) and nonchondrodystrophic dogs (NCD) can be used as a valid translational model for human IVDD research. Summary of Background Data. Different animal models are used in IVDD research, but in most of these models IVDD is induced manually or chemically rather than occurring spontaneously. Methods. A total of 184 intervertebral discs (IVDs) from 19 dogs of different breeds were used. The extent of IVDD was evaluated by macroscopic grading, histopathology, glycosaminoglycan content, and matrix metalloproteinase 2 activity. Canine data were compared with human IVD data acquired in this study or from the literature. Results. Gross pathology of IVDD in both dog types (CD and NCD) and humans showed many similarities, but the cartilaginous endplates were signifi cantly thicker and the subchondral cortices signifi cantly thinner in humans than in dogs. Notochordal cells were still present in the IVDs of adult NCD but were not seen in the CD breeds or in humans. Signs of degeneration were seen in young dogs of CD breeds ( \u003c 1 year of age), whereas this was only seen in older dogs of NCD breeds (5-7 years of age). The relative glycosaminoglycan content and metalloproteinase 2 activity in canine IVDD were similar to those in humans: metalloproteinase 2 activity increased and glycosaminoglycan content decreased with increasing severity of IVDD. Conclusion. IVDD is similar in humans and dogs. Both CD and NCD breeds may therefore serve as models of spontaneous IVDD for human research. However, as with all animal models, it is important to recognize interspecies differences and, indeed, the intraspecies differences between CD and NCD breeds (early vs. late onset of IVDD, respectively) to develop an optimal canine model of human IVDD.","downloadable_attachments":[{"id":48286519,"asset_id":27984081,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33399028,"first_name":"Niklas","last_name":"Bergknut","domain_name":"independent","page_name":"NiklasBergknut","display_name":"Niklas Bergknut","profile_url":"https://independent.academia.edu/NiklasBergknut?f_ri=62112","photo":"https://0.academia-photos.com/33399028/13905881/14972206/s65_niklas.bergknut.jpg"},{"id":52466949,"first_name":"Anne-Sofie","last_name":"Lagerstedt","domain_name":"independent","page_name":"AnneSofieLagerstedt","display_name":"Anne-Sofie Lagerstedt","profile_url":"https://independent.academia.edu/AnneSofieLagerstedt?f_ri=62112","photo":"/images/s65_no_pic.png"},{"id":36418607,"first_name":"Björn","last_name":"Meij","domain_name":"uu","page_name":"BjörnMeij","display_name":"Björn Meij","profile_url":"https://uu.academia.edu/Bj%C3%B6rnMeij?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":1131,"name":"Biomedical Engineering","url":"https://www.academia.edu/Documents/in/Biomedical_Engineering?f_ri=62112","nofollow":true},{"id":4933,"name":"Spine","url":"https://www.academia.edu/Documents/in/Spine?f_ri=62112","nofollow":true},{"id":6791,"name":"Aging","url":"https://www.academia.edu/Documents/in/Aging?f_ri=62112","nofollow":true},{"id":52438,"name":"Dogs","url":"https://www.academia.edu/Documents/in/Dogs?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112"},{"id":133360,"name":"Intervertebral disc","url":"https://www.academia.edu/Documents/in/Intervertebral_disc?f_ri=62112"},{"id":193017,"name":"Intervertebral disc degeneration","url":"https://www.academia.edu/Documents/in/Intervertebral_disc_degeneration?f_ri=62112"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112"},{"id":784076,"name":"Species Specificity","url":"https://www.academia.edu/Documents/in/Species_Specificity?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_8274074" data-work_id="8274074" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/8274074/Topical_amethocaine_Ametop_is_superior_to_EMLA_for_intravenous_cannulation">Topical amethocaine (Ametop™) is superior to EMLA for intravenous cannulation</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Purpose A eutectic mixture of local anesthetics (EMLA) is commonly used to provide topical anesthesia for intravenous (iv) cannulation. One of its side effects is vasoconstriction, which may render cannulation more difficult. A gel... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_8274074" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Purpose A eutectic mixture of local anesthetics (EMLA) is commonly used to provide topical anesthesia for intravenous (iv) cannulation. One of its side effects is vasoconstriction, which may render cannulation more difficult. A gel formulation of amethocaine (Ametop™) is now commercially available. The aim of this study was to compare EMLA and Ametop™ with regard to the degree of topical anesthesia afforded, the incidence of vasoconstriction and the ease of iv cannulation. Methods Thirty two ASA 1 adult volunteers had a # 16 gauge iv cannula inserted on two separate occasions using EMLA and Ametop™ applied in a double blind fashion for topical anesthesia. Parameters that were recorded after each cannulation included visual analogue pain scores (VAPS), the presence of vasoconstriction and the ease of cannulation, graded as: 1 = easy, 2 = moderately difficult, 3 = difficult and 4 = failed. Results The mean VAPS ± SD after cannulation with Ametop™ M was 12 ± 9.9 and with EMLA was 25.3 ± 16.6 (P = 0.002). Vasoconstriction occurred after EMLA application on 17 occasions and twice after Ametop™ (P = 0.001). The grade of difficulty of cannulation was 1.44 ± 0.88 following EMLA and 1.06 ± 0.25 with Ametop™ (P = 0.023). Conclusions Intravenous cannulation was less painful following application of Ametop™ than EMLA. In addition, Ametop™ caused less vasoconstriction and facilitated easier cannulation. Its use as a topical anesthetic agent is recommended, especially when iv access may be problematic. Objectif Un mélange eutectique d’anesthésiques locaux (MEAL) est souvent utilisé pour l’anesthésie topique lors d’une canulation intraveineuse (iv). La vasoconstriction, qui est l’un des effets secondaires du MEAL, peut compliquer la mise en place d’une canule. Une présentation en gel d’améthocaïne (Ametop™) est maintenant offerte dans le commerce. Le but de la présente étude était de comparer le MEAL et l’Ametop™ en regard du degré d’anesthésie topique fourni, de l’incidence de la vasoconstriction et de la facilité de la canulation iv. Méthode: On a inséré, en deux occasions séparées chez 32 volontaires adultes d’état physique ASA 1, une canuleiv de calibre 16 en utilisant en double aveugle le MEAL et Ametop™ pour réaliser l’anesthésie topique. Après chaque canulation, on a enregistré les paramètres suivants: les scores de douleur à l’échelle visuelle analogue (EVA), la présence de vasoconstriction et la facilité de canulation notée 1 = facile, 2 = modérément difficile, 3 = difficile et 4 = impossible. Résultats Les scores moyens à l’EVA ± l’écart type ont été de 12 ± 9,9 à la suite de la canulation avec Ametop™ M et de 25,3 ± 16,6 après le MEAL (P = 0,002). La vasoconstriction est survenue en 17 occasions après l’application du MEAL et deux fois plus souvent après Ametop™ (P = 0,001). Le degré de difficulté de canulation a été de 1,44 ± 0,88 après le MEAL et de 1,06 ± 0,25 après Ametop™ (P = 0,023). Conclusion La canulation intraveineuse est moins douloureuse après l’application d’Ametop™ que celle du MEAL. De plus, l’Ametop™ a provoqué moins de vasoconstriction et a facilité l’introduction d’une canule. Son usage comme anesthésique topique est recommandé, surtout lorsqu’une action rapide est nécessaire ou que l’accèsiv peut être problématique.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/8274074" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="961cdc1634dfd5c84af72030f0dd684d" rel="nofollow" data-download="{"attachment_id":48159050,"asset_id":8274074,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48159050/download_file?st=MTczOTgwMzc0NSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="16399742" href="https://ucc-ie.academia.edu/RobertPlant">Robert Plant</a><script data-card-contents-for-user="16399742" type="text/json">{"id":16399742,"first_name":"Robert","last_name":"Plant","domain_name":"ucc-ie","page_name":"RobertPlant","display_name":"Robert Plant","profile_url":"https://ucc-ie.academia.edu/RobertPlant?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_8274074 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="8274074"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 8274074, container: ".js-paper-rank-work_8274074", }); 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$(".js-view-count[data-work-id=8274074]").text(description); $(".js-view-count-work_8274074").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_8274074").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="8274074"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="56615" rel="nofollow" href="https://www.academia.edu/Documents/in/Canadian">Canadian</a>, <script data-card-contents-for-ri="56615" type="text/json">{"id":56615,"name":"Canadian","url":"https://www.academia.edu/Documents/in/Canadian?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a>, <script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="204388" rel="nofollow" href="https://www.academia.edu/Documents/in/Vasoconstriction">Vasoconstriction</a>, <script data-card-contents-for-ri="204388" type="text/json">{"id":204388,"name":"Vasoconstriction","url":"https://www.academia.edu/Documents/in/Vasoconstriction?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" rel="nofollow" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a><script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=8274074]'), work: {"id":8274074,"title":"Topical amethocaine (Ametop™) is superior to EMLA for intravenous cannulation","created_at":"2014-09-10T07:36:09.454-07:00","url":"https://www.academia.edu/8274074/Topical_amethocaine_Ametop_is_superior_to_EMLA_for_intravenous_cannulation?f_ri=62112","dom_id":"work_8274074","summary":"Purpose A eutectic mixture of local anesthetics (EMLA) is commonly used to provide topical anesthesia for intravenous (iv) cannulation. One of its side effects is vasoconstriction, which may render cannulation more difficult. A gel formulation of amethocaine (Ametop™) is now commercially available. The aim of this study was to compare EMLA and Ametop™ with regard to the degree of topical anesthesia afforded, the incidence of vasoconstriction and the ease of iv cannulation. Methods Thirty two ASA 1 adult volunteers had a # 16 gauge iv cannula inserted on two separate occasions using EMLA and Ametop™ applied in a double blind fashion for topical anesthesia. Parameters that were recorded after each cannulation included visual analogue pain scores (VAPS), the presence of vasoconstriction and the ease of cannulation, graded as: 1 = easy, 2 = moderately difficult, 3 = difficult and 4 = failed. Results The mean VAPS ± SD after cannulation with Ametop™ M was 12 ± 9.9 and with EMLA was 25.3 ± 16.6 (P = 0.002). Vasoconstriction occurred after EMLA application on 17 occasions and twice after Ametop™ (P = 0.001). The grade of difficulty of cannulation was 1.44 ± 0.88 following EMLA and 1.06 ± 0.25 with Ametop™ (P = 0.023). Conclusions Intravenous cannulation was less painful following application of Ametop™ than EMLA. In addition, Ametop™ caused less vasoconstriction and facilitated easier cannulation. Its use as a topical anesthetic agent is recommended, especially when iv access may be problematic. Objectif Un mélange eutectique d’anesthésiques locaux (MEAL) est souvent utilisé pour l’anesthésie topique lors d’une canulation intraveineuse (iv). La vasoconstriction, qui est l’un des effets secondaires du MEAL, peut compliquer la mise en place d’une canule. Une présentation en gel d’améthocaïne (Ametop™) est maintenant offerte dans le commerce. Le but de la présente étude était de comparer le MEAL et l’Ametop™ en regard du degré d’anesthésie topique fourni, de l’incidence de la vasoconstriction et de la facilité de la canulation iv. Méthode: On a inséré, en deux occasions séparées chez 32 volontaires adultes d’état physique ASA 1, une canuleiv de calibre 16 en utilisant en double aveugle le MEAL et Ametop™ pour réaliser l’anesthésie topique. Après chaque canulation, on a enregistré les paramètres suivants: les scores de douleur à l’échelle visuelle analogue (EVA), la présence de vasoconstriction et la facilité de canulation notée 1 = facile, 2 = modérément difficile, 3 = difficile et 4 = impossible. Résultats Les scores moyens à l’EVA ± l’écart type ont été de 12 ± 9,9 à la suite de la canulation avec Ametop™ M et de 25,3 ± 16,6 après le MEAL (P = 0,002). La vasoconstriction est survenue en 17 occasions après l’application du MEAL et deux fois plus souvent après Ametop™ (P = 0,001). Le degré de difficulté de canulation a été de 1,44 ± 0,88 après le MEAL et de 1,06 ± 0,25 après Ametop™ (P = 0,023). Conclusion La canulation intraveineuse est moins douloureuse après l’application d’Ametop™ que celle du MEAL. De plus, l’Ametop™ a provoqué moins de vasoconstriction et a facilité l’introduction d’une canule. Son usage comme anesthésique topique est recommandé, surtout lorsqu’une action rapide est nécessaire ou que l’accèsiv peut être problématique.","downloadable_attachments":[{"id":48159050,"asset_id":8274074,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":16399742,"first_name":"Robert","last_name":"Plant","domain_name":"ucc-ie","page_name":"RobertPlant","display_name":"Robert Plant","profile_url":"https://ucc-ie.academia.edu/RobertPlant?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":56615,"name":"Canadian","url":"https://www.academia.edu/Documents/in/Canadian?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":204388,"name":"Vasoconstriction","url":"https://www.academia.edu/Documents/in/Vasoconstriction?f_ri=62112","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112","nofollow":true},{"id":375078,"name":"Topical Drug Administration","url":"https://www.academia.edu/Documents/in/Topical_Drug_Administration?f_ri=62112"},{"id":468993,"name":"Lidocaine","url":"https://www.academia.edu/Documents/in/Lidocaine?f_ri=62112"},{"id":698785,"name":"Side Effect","url":"https://www.academia.edu/Documents/in/Side_Effect?f_ri=62112"},{"id":1558760,"name":"Tetracaine","url":"https://www.academia.edu/Documents/in/Tetracaine?f_ri=62112"},{"id":1558817,"name":"Prilocaine","url":"https://www.academia.edu/Documents/in/Prilocaine?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_28393195" data-work_id="28393195" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/28393195/Doppler_and_biophysical_assessment_in_growth_restricted_fetuses_distribution_of_test_results">Doppler and biophysical assessment in growth restricted fetuses: distribution of test results</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Methods Three hundred and twenty-eight IUGR fetuses (abdominal circumference < 5th percentile, elevated umbilical artery (UA) pulsatility index (PI)) had concurrent surveillance with UA, middle cerebral artery (MCA) and ductus venosus... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_28393195" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Methods Three hundred and twenty-eight IUGR fetuses (abdominal circumference < 5th percentile, elevated umbilical artery (UA) pulsatility index (PI)) had concurrent surveillance with UA, middle cerebral artery (MCA) and ductus venosus (DV) Doppler ultrasonography and BPS (fetal tone, movement, breathing, maximal amniotic fluid pocket and fetal heart rate). Patients were stratified into three groups according to their Doppler examination: (1) abnormal UA alone; (2) brain sparing (MCA-PI > 2 SD below mean for gestational age); and (3) abnormal DV (PI > 2 SD above the mean for gestational age) and BPS groups: (1) normal (> 6/10);</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/28393195" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="5d8e9c78a3e5a09a986c4a5868e06905" rel="nofollow" data-download="{"attachment_id":48730920,"asset_id":28393195,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48730920/download_file?st=MTczOTgwMzc0NSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="41454605" href="https://independent.academia.edu/ChristophBerg">Christoph Berg</a><script data-card-contents-for-user="41454605" type="text/json">{"id":41454605,"first_name":"Christoph","last_name":"Berg","domain_name":"independent","page_name":"ChristophBerg","display_name":"Christoph Berg","profile_url":"https://independent.academia.edu/ChristophBerg?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_28393195 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="28393195"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 28393195, container: ".js-paper-rank-work_28393195", }); 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$(".js-view-count[data-work-id=28393195]").text(description); $(".js-view-count-work_28393195").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_28393195").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="28393195"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">11</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="502" rel="nofollow" href="https://www.academia.edu/Documents/in/Biophysics">Biophysics</a>, <script data-card-contents-for-ri="502" type="text/json">{"id":502,"name":"Biophysics","url":"https://www.academia.edu/Documents/in/Biophysics?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="625" rel="nofollow" href="https://www.academia.edu/Documents/in/Obstetrics">Obstetrics</a>, <script data-card-contents-for-ri="625" type="text/json">{"id":625,"name":"Obstetrics","url":"https://www.academia.edu/Documents/in/Obstetrics?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a><script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=28393195]'), work: {"id":28393195,"title":"Doppler and biophysical assessment in growth restricted fetuses: distribution of test results","created_at":"2016-09-10T10:28:37.574-07:00","url":"https://www.academia.edu/28393195/Doppler_and_biophysical_assessment_in_growth_restricted_fetuses_distribution_of_test_results?f_ri=62112","dom_id":"work_28393195","summary":"Methods Three hundred and twenty-eight IUGR fetuses (abdominal circumference \u003c 5th percentile, elevated umbilical artery (UA) pulsatility index (PI)) had concurrent surveillance with UA, middle cerebral artery (MCA) and ductus venosus (DV) Doppler ultrasonography and BPS (fetal tone, movement, breathing, maximal amniotic fluid pocket and fetal heart rate). Patients were stratified into three groups according to their Doppler examination: (1) abnormal UA alone; (2) brain sparing (MCA-PI \u003e 2 SD below mean for gestational age); and (3) abnormal DV (PI \u003e 2 SD above the mean for gestational age) and BPS groups: (1) normal (\u003e 6/10);","downloadable_attachments":[{"id":48730920,"asset_id":28393195,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":41454605,"first_name":"Christoph","last_name":"Berg","domain_name":"independent","page_name":"ChristophBerg","display_name":"Christoph Berg","profile_url":"https://independent.academia.edu/ChristophBerg?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":502,"name":"Biophysics","url":"https://www.academia.edu/Documents/in/Biophysics?f_ri=62112","nofollow":true},{"id":625,"name":"Obstetrics","url":"https://www.academia.edu/Documents/in/Obstetrics?f_ri=62112","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":62550,"name":"Pregnancy","url":"https://www.academia.edu/Documents/in/Pregnancy?f_ri=62112"},{"id":161719,"name":"Amniotic Fluid","url":"https://www.academia.edu/Documents/in/Amniotic_Fluid?f_ri=62112"},{"id":202428,"name":"Respiration","url":"https://www.academia.edu/Documents/in/Respiration?f_ri=62112"},{"id":571738,"name":"Internal medicine Doppler ultrasonography","url":"https://www.academia.edu/Documents/in/Internal_medicine_Doppler_ultrasonography?f_ri=62112"},{"id":770944,"name":"Fetus","url":"https://www.academia.edu/Documents/in/Fetus?f_ri=62112"},{"id":1318932,"name":"Predictive value of tests","url":"https://www.academia.edu/Documents/in/Predictive_value_of_tests?f_ri=62112"},{"id":1434623,"name":"Pulsatile Flow","url":"https://www.academia.edu/Documents/in/Pulsatile_Flow?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_65472713" data-work_id="65472713" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/65472713/Head_injury_in_very_young_children_Mechanisms_injury_types_and_ophthalmologic_findings_in_100_hospitalized_patients_younger_than_2_years_of_age">Head injury in very young children: Mechanisms, injury types, and ophthalmologic findings in 100 hospitalized patients younger than 2 years of age</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/65472713" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="cb90d218e589fe634159fc7532897477" rel="nofollow" data-download="{"attachment_id":77054045,"asset_id":65472713,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/77054045/download_file?st=MTczOTgwMzc0NSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="35094454" href="https://independent.academia.edu/DBudenz">D. Budenz</a><script data-card-contents-for-user="35094454" type="text/json">{"id":35094454,"first_name":"D.","last_name":"Budenz","domain_name":"independent","page_name":"DBudenz","display_name":"D. 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Budenz","profile_url":"https://independent.academia.edu/DBudenz?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=62112","nofollow":true},{"id":631,"name":"Pediatrics","url":"https://www.academia.edu/Documents/in/Pediatrics?f_ri=62112","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":91079,"name":"Child Abuse","url":"https://www.academia.edu/Documents/in/Child_Abuse?f_ri=62112"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=62112"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112"},{"id":253560,"name":"Newborn Infant","url":"https://www.academia.edu/Documents/in/Newborn_Infant?f_ri=62112"},{"id":368876,"name":"Head injury","url":"https://www.academia.edu/Documents/in/Head_injury?f_ri=62112"},{"id":1159940,"name":"Cerebral Hemorrhage","url":"https://www.academia.edu/Documents/in/Cerebral_Hemorrhage?f_ri=62112"},{"id":1902100,"name":"Biomechanical Phenomena","url":"https://www.academia.edu/Documents/in/Biomechanical_Phenomena?f_ri=62112"},{"id":2489700,"name":"Child preschool","url":"https://www.academia.edu/Documents/in/Child_preschool?f_ri=62112"},{"id":2922956,"name":"Psychology and Cognitive Sciences","url":"https://www.academia.edu/Documents/in/Psychology_and_Cognitive_Sciences?f_ri=62112"},{"id":3761707,"name":"Accidental falls","url":"https://www.academia.edu/Documents/in/Accidental_falls?f_ri=62112"},{"id":3763225,"name":"Medical and Health Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences?f_ri=62112"},{"id":4002452,"name":"Accidents Traffic","url":"https://www.academia.edu/Documents/in/Accidents_Traffic?f_ri=62112"},{"id":4022567,"name":"Brain concussion","url":"https://www.academia.edu/Documents/in/Brain_concussion?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_22839514" data-work_id="22839514" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/22839514/Cryopreservation_of_human_spermatozoa_Comparison_of_two_cryopreservation_methods_and_three_cryoprotectants">Cryopreservation of human spermatozoa: Comparison of two cryopreservation methods and three cryoprotectants</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objective: To evaluate the ability of two cryopreservation methods and three cryoprotectants to preserve sperm quality. Design: A prospective clinical study. Setting: Male infertility clinic at a tertiary healthcare center. Patient(s):... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_22839514" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objective: To evaluate the ability of two cryopreservation methods and three cryoprotectants to preserve sperm quality. Design: A prospective clinical study. Setting: Male infertility clinic at a tertiary healthcare center. Patient(s): Twenty infertile men and 10 healthy donors. Intervention(s): In the first experiment, semen was cryopreserved by either the Irvine Scientific method (IS) or the Cleveland Clinic Foundation (CCF) method. In the second experiment, semen was cryopreserved by the IS method and one of three cryoprotectants: TES and Tris yolk buffer, Sperm Freezing Medium, or Enhance Sperm Freeze. Main Outcome Measure(s): Postthaw sperm motility, cryosurvival, and kinematics. Result(s): Percentages of postthaw sperm motility and cryosurvival were higher in the IS cryopreservation method compared with in the CCF method (15.94 Ϯ 9.19 vs. 12.07 Ϯ 7. 31 and 47.42 Ϯ 17.44 vs. 35.76 Ϯ 17.56). However, the CCF method resulted in significantly better sperm kinematics. Postthaw motility in the donors and patients was highest in the samples frozen in TES and Tris yolk buffer medium.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/22839514" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="795f998d8d0c4fe3bab69306c5b48987" rel="nofollow" data-download="{"attachment_id":43384279,"asset_id":22839514,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/43384279/download_file?st=MTczOTgwMzc0NSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="44494217" href="https://liverpool.academia.edu/NabilAziz">Nabil Aziz</a><script data-card-contents-for-user="44494217" type="text/json">{"id":44494217,"first_name":"Nabil","last_name":"Aziz","domain_name":"liverpool","page_name":"NabilAziz","display_name":"Nabil Aziz","profile_url":"https://liverpool.academia.edu/NabilAziz?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_22839514 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="22839514"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 22839514, container: ".js-paper-rank-work_22839514", }); 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$(".js-view-count[data-work-id=22839514]").text(description); $(".js-view-count-work_22839514").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_22839514").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="22839514"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">8</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="19295" rel="nofollow" href="https://www.academia.edu/Documents/in/Cryopreservation">Cryopreservation</a>, <script data-card-contents-for-ri="19295" type="text/json">{"id":19295,"name":"Cryopreservation","url":"https://www.academia.edu/Documents/in/Cryopreservation?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a>, <script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="98922" rel="nofollow" href="https://www.academia.edu/Documents/in/Fertility_and_Sterility">Fertility and Sterility</a>, <script data-card-contents-for-ri="98922" type="text/json">{"id":98922,"name":"Fertility and Sterility","url":"https://www.academia.edu/Documents/in/Fertility_and_Sterility?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" rel="nofollow" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a><script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=22839514]'), work: {"id":22839514,"title":"Cryopreservation of human spermatozoa: Comparison of two cryopreservation methods and three cryoprotectants","created_at":"2016-03-05T03:05:50.763-08:00","url":"https://www.academia.edu/22839514/Cryopreservation_of_human_spermatozoa_Comparison_of_two_cryopreservation_methods_and_three_cryoprotectants?f_ri=62112","dom_id":"work_22839514","summary":"Objective: To evaluate the ability of two cryopreservation methods and three cryoprotectants to preserve sperm quality. Design: A prospective clinical study. Setting: Male infertility clinic at a tertiary healthcare center. Patient(s): Twenty infertile men and 10 healthy donors. Intervention(s): In the first experiment, semen was cryopreserved by either the Irvine Scientific method (IS) or the Cleveland Clinic Foundation (CCF) method. In the second experiment, semen was cryopreserved by the IS method and one of three cryoprotectants: TES and Tris yolk buffer, Sperm Freezing Medium, or Enhance Sperm Freeze. Main Outcome Measure(s): Postthaw sperm motility, cryosurvival, and kinematics. Result(s): Percentages of postthaw sperm motility and cryosurvival were higher in the IS cryopreservation method compared with in the CCF method (15.94 Ϯ 9.19 vs. 12.07 Ϯ 7. 31 and 47.42 Ϯ 17.44 vs. 35.76 Ϯ 17.56). However, the CCF method resulted in significantly better sperm kinematics. Postthaw motility in the donors and patients was highest in the samples frozen in TES and Tris yolk buffer medium.","downloadable_attachments":[{"id":43384279,"asset_id":22839514,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":44494217,"first_name":"Nabil","last_name":"Aziz","domain_name":"liverpool","page_name":"NabilAziz","display_name":"Nabil Aziz","profile_url":"https://liverpool.academia.edu/NabilAziz?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":19295,"name":"Cryopreservation","url":"https://www.academia.edu/Documents/in/Cryopreservation?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":98922,"name":"Fertility and Sterility","url":"https://www.academia.edu/Documents/in/Fertility_and_Sterility?f_ri=62112","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112","nofollow":true},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=62112"},{"id":897073,"name":"Sperm Motility","url":"https://www.academia.edu/Documents/in/Sperm_Motility?f_ri=62112"},{"id":963536,"name":"Sperm Count","url":"https://www.academia.edu/Documents/in/Sperm_Count?f_ri=62112"},{"id":1043331,"name":"Semen Preservation","url":"https://www.academia.edu/Documents/in/Semen_Preservation?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_20132581" data-work_id="20132581" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/20132581/Comparison_of_two_versions_of_the_Vigileo_FloTracTM_system_1_03_and_1_07_for_stroke_volume_estimation_a_multicentre_blinded_comparison_with_oesophageal_Doppler_measurements">Comparison of two versions of the Vigileo-FloTracTM system (1.03 and 1.07) for stroke volume estimation: a multicentre, blinded comparison with oesophageal Doppler measurements</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">Background. Our aim was to evaluate the validity of stroke volume measurements obtained using the Vigileo-FloTrac TM system in comparison with those obtained using oesophageal Doppler considered as a reference.</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/20132581" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="3e9aac63139ea4744ccf87ca51634c25" rel="nofollow" data-download="{"attachment_id":41225493,"asset_id":20132581,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/41225493/download_file?st=MTczOTgwMzc0NSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="41208943" href="https://independent.academia.edu/StephaneRudnicki">Stephane Rudnicki</a><script data-card-contents-for-user="41208943" type="text/json">{"id":41208943,"first_name":"Stephane","last_name":"Rudnicki","domain_name":"independent","page_name":"StephaneRudnicki","display_name":"Stephane Rudnicki","profile_url":"https://independent.academia.edu/StephaneRudnicki?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_20132581 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="20132581"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 20132581, container: ".js-paper-rank-work_20132581", }); });</script></li><li class="js-percentile-work_20132581 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 20132581; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_20132581"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_20132581 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="20132581"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 20132581; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=20132581]").text(description); $(".js-view-count-work_20132581").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_20132581").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="20132581"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">10</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="53293" rel="nofollow" href="https://www.academia.edu/Documents/in/Software">Software</a>, <script data-card-contents-for-ri="53293" type="text/json">{"id":53293,"name":"Software","url":"https://www.academia.edu/Documents/in/Software?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a>, <script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="74347" rel="nofollow" href="https://www.academia.edu/Documents/in/Hemodynamics">Hemodynamics</a>, <script data-card-contents-for-ri="74347" type="text/json">{"id":74347,"name":"Hemodynamics","url":"https://www.academia.edu/Documents/in/Hemodynamics?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="94234" rel="nofollow" href="https://www.academia.edu/Documents/in/INTENSIVE_CARE">INTENSIVE CARE</a><script data-card-contents-for-ri="94234" type="text/json">{"id":94234,"name":"INTENSIVE CARE","url":"https://www.academia.edu/Documents/in/INTENSIVE_CARE?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=20132581]'), work: {"id":20132581,"title":"Comparison of two versions of the Vigileo-FloTracTM system (1.03 and 1.07) for stroke volume estimation: a multicentre, blinded comparison with oesophageal Doppler measurements","created_at":"2016-01-10T01:58:40.803-08:00","url":"https://www.academia.edu/20132581/Comparison_of_two_versions_of_the_Vigileo_FloTracTM_system_1_03_and_1_07_for_stroke_volume_estimation_a_multicentre_blinded_comparison_with_oesophageal_Doppler_measurements?f_ri=62112","dom_id":"work_20132581","summary":"Background. Our aim was to evaluate the validity of stroke volume measurements obtained using the Vigileo-FloTrac TM system in comparison with those obtained using oesophageal Doppler considered as a reference.","downloadable_attachments":[{"id":41225493,"asset_id":20132581,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":41208943,"first_name":"Stephane","last_name":"Rudnicki","domain_name":"independent","page_name":"StephaneRudnicki","display_name":"Stephane Rudnicki","profile_url":"https://independent.academia.edu/StephaneRudnicki?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":53293,"name":"Software","url":"https://www.academia.edu/Documents/in/Software?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":74347,"name":"Hemodynamics","url":"https://www.academia.edu/Documents/in/Hemodynamics?f_ri=62112","nofollow":true},{"id":94234,"name":"INTENSIVE CARE","url":"https://www.academia.edu/Documents/in/INTENSIVE_CARE?f_ri=62112","nofollow":true},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=62112"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=62112"},{"id":601516,"name":"Flow Velocity","url":"https://www.academia.edu/Documents/in/Flow_Velocity?f_ri=62112"},{"id":647820,"name":"Fluid Therapy","url":"https://www.academia.edu/Documents/in/Fluid_Therapy?f_ri=62112"},{"id":1157501,"name":"Blood Flow Velocity","url":"https://www.academia.edu/Documents/in/Blood_Flow_Velocity?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_54513290" data-work_id="54513290" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/54513290/Mannose_binding_lectin_MBL_substitution_recovery_of_opsonic_function_in_vivo_lags_behind_MBL_serum_levels">Mannose-binding lectin (MBL) substitution: recovery of opsonic function in vivo lags behind MBL serum levels</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">Table of Contents Chapter 1 Introduction Chapter 2 Mannan-binding lectin (MBL)-mediated opsonization is enhanced by the alternative pathway amplification loop</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/54513290" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="488989f9d3cbdf5083f078095faa94b3" rel="nofollow" data-download="{"attachment_id":70841392,"asset_id":54513290,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/70841392/download_file?st=MTczOTgwMzc0NSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="36158831" href="https://independent.academia.edu/PStrengers">P. Strengers</a><script data-card-contents-for-user="36158831" type="text/json">{"id":36158831,"first_name":"P.","last_name":"Strengers","domain_name":"independent","page_name":"PStrengers","display_name":"P. Strengers","profile_url":"https://independent.academia.edu/PStrengers?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_54513290 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="54513290"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 54513290, container: ".js-paper-rank-work_54513290", }); });</script></li><li class="js-percentile-work_54513290 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 54513290; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_54513290"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_54513290 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="54513290"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 54513290; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=54513290]").text(description); $(".js-view-count-work_54513290").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_54513290").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="54513290"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">14</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="1290" rel="nofollow" href="https://www.academia.edu/Documents/in/Immunology">Immunology</a>, <script data-card-contents-for-ri="1290" type="text/json">{"id":1290,"name":"Immunology","url":"https://www.academia.edu/Documents/in/Immunology?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="2705" rel="nofollow" href="https://www.academia.edu/Documents/in/Complement_activation">Complement activation</a>, <script data-card-contents-for-ri="2705" type="text/json">{"id":2705,"name":"Complement activation","url":"https://www.academia.edu/Documents/in/Complement_activation?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="18327" rel="nofollow" href="https://www.academia.edu/Documents/in/Immunology_of_the_Gut">Immunology of the Gut</a>, <script data-card-contents-for-ri="18327" type="text/json">{"id":18327,"name":"Immunology of the Gut","url":"https://www.academia.edu/Documents/in/Immunology_of_the_Gut?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a><script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=54513290]'), work: {"id":54513290,"title":"Mannose-binding lectin (MBL) substitution: recovery of opsonic function in vivo lags behind MBL serum levels","created_at":"2021-09-30T23:59:12.248-07:00","url":"https://www.academia.edu/54513290/Mannose_binding_lectin_MBL_substitution_recovery_of_opsonic_function_in_vivo_lags_behind_MBL_serum_levels?f_ri=62112","dom_id":"work_54513290","summary":"Table of Contents Chapter 1 Introduction Chapter 2 Mannan-binding lectin (MBL)-mediated opsonization is enhanced by the alternative pathway amplification loop","downloadable_attachments":[{"id":70841392,"asset_id":54513290,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":36158831,"first_name":"P.","last_name":"Strengers","domain_name":"independent","page_name":"PStrengers","display_name":"P. Strengers","profile_url":"https://independent.academia.edu/PStrengers?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":1290,"name":"Immunology","url":"https://www.academia.edu/Documents/in/Immunology?f_ri=62112","nofollow":true},{"id":2705,"name":"Complement activation","url":"https://www.academia.edu/Documents/in/Complement_activation?f_ri=62112","nofollow":true},{"id":18327,"name":"Immunology of the Gut","url":"https://www.academia.edu/Documents/in/Immunology_of_the_Gut?f_ri=62112","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=62112"},{"id":161176,"name":"The","url":"https://www.academia.edu/Documents/in/The?f_ri=62112"},{"id":376644,"name":"Phagocytosis","url":"https://www.academia.edu/Documents/in/Phagocytosis?f_ri=62112"},{"id":783432,"name":"Biological activity","url":"https://www.academia.edu/Documents/in/Biological_activity?f_ri=62112"},{"id":894908,"name":"Amino Acid Substitution Rates","url":"https://www.academia.edu/Documents/in/Amino_Acid_Substitution_Rates?f_ri=62112"},{"id":1114258,"name":"Level","url":"https://www.academia.edu/Documents/in/Level?f_ri=62112"},{"id":2489700,"name":"Child preschool","url":"https://www.academia.edu/Documents/in/Child_preschool?f_ri=62112"},{"id":2969290,"name":"neutropenia","url":"https://www.academia.edu/Documents/in/neutropenia?f_ri=62112"},{"id":3630019,"name":"mannose binding lectin","url":"https://www.academia.edu/Documents/in/mannose_binding_lectin?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_9589984" data-work_id="9589984" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/9589984/Doctor_Patient_Communication_Health_Related_Beliefs_and_Adherence_in_Glaucoma">Doctor–Patient Communication, Health-Related Beliefs, and Adherence in Glaucoma</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">Objective: To use multiple data sources to determine drivers of patient adherence to topical ocular hypotensive therapy.</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/9589984" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="15563bfde8283a3bcfdfb1f9958bf9ed" rel="nofollow" data-download="{"attachment_id":47714345,"asset_id":9589984,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/47714345/download_file?st=MTczOTgwMzc0NSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="22721789" href="https://independent.academia.edu/JasonTan23">Jason Tan</a><script data-card-contents-for-user="22721789" type="text/json">{"id":22721789,"first_name":"Jason","last_name":"Tan","domain_name":"independent","page_name":"JasonTan23","display_name":"Jason Tan","profile_url":"https://independent.academia.edu/JasonTan23?f_ri=62112","photo":"https://0.academia-photos.com/22721789/23981691/22972889/s65_jason.tan.jpg"}</script></span></span></li><li class="js-paper-rank-work_9589984 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="9589984"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 9589984, container: ".js-paper-rank-work_9589984", }); });</script></li><li class="js-percentile-work_9589984 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 9589984; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_9589984"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_9589984 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="9589984"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 9589984; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=9589984]").text(description); $(".js-view-count-work_9589984").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_9589984").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="9589984"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="627" rel="nofollow" href="https://www.academia.edu/Documents/in/Ophthalmology">Ophthalmology</a>, <script data-card-contents-for-ri="627" type="text/json">{"id":627,"name":"Ophthalmology","url":"https://www.academia.edu/Documents/in/Ophthalmology?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="859" rel="nofollow" href="https://www.academia.edu/Documents/in/Communication">Communication</a>, <script data-card-contents-for-ri="859" type="text/json">{"id":859,"name":"Communication","url":"https://www.academia.edu/Documents/in/Communication?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="20878" rel="nofollow" href="https://www.academia.edu/Documents/in/Doctor-patient_communication">Doctor-patient communication</a>, <script data-card-contents-for-ri="20878" type="text/json">{"id":20878,"name":"Doctor-patient communication","url":"https://www.academia.edu/Documents/in/Doctor-patient_communication?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a><script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=9589984]'), work: {"id":9589984,"title":"Doctor–Patient Communication, Health-Related Beliefs, and Adherence in Glaucoma","created_at":"2014-12-02T03:10:50.881-08:00","url":"https://www.academia.edu/9589984/Doctor_Patient_Communication_Health_Related_Beliefs_and_Adherence_in_Glaucoma?f_ri=62112","dom_id":"work_9589984","summary":"Objective: To use multiple data sources to determine drivers of patient adherence to topical ocular hypotensive therapy.","downloadable_attachments":[{"id":47714345,"asset_id":9589984,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":22721789,"first_name":"Jason","last_name":"Tan","domain_name":"independent","page_name":"JasonTan23","display_name":"Jason Tan","profile_url":"https://independent.academia.edu/JasonTan23?f_ri=62112","photo":"https://0.academia-photos.com/22721789/23981691/22972889/s65_jason.tan.jpg"}],"research_interests":[{"id":627,"name":"Ophthalmology","url":"https://www.academia.edu/Documents/in/Ophthalmology?f_ri=62112","nofollow":true},{"id":859,"name":"Communication","url":"https://www.academia.edu/Documents/in/Communication?f_ri=62112","nofollow":true},{"id":20878,"name":"Doctor-patient communication","url":"https://www.academia.edu/Documents/in/Doctor-patient_communication?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":135005,"name":"Patient Compliance","url":"https://www.academia.edu/Documents/in/Patient_Compliance?f_ri=62112"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112"},{"id":359001,"name":"Optometry and Ophthalmology","url":"https://www.academia.edu/Documents/in/Optometry_and_Ophthalmology?f_ri=62112"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=62112"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_43849672" data-work_id="43849672" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/43849672/Using_the_theory_of_planned_behavior_to_predict_gambling_behavior">Using the theory of planned behavior to predict gambling behavior</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Gambling is an important public health concern. To better understand gambling behavior, we conducted a classroom-based survey that assessed the role of the theory of planned behavior (TPB; i.e., intentions, subjective norms, perceived... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_43849672" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Gambling is an important public health concern. To better understand gambling behavior, we conducted a classroom-based survey that assessed the role of the theory of planned behavior (TPB; i.e., intentions, subjective norms, perceived behavioral control, and attitudes) in past year gambling and gambling frequency among college students. Results from this research support the utility of the TPB to explain gambling behavior in this population. Specifically, in TPB models to predict gambling behavior, friend and family subjective norms and perceived behavioral control predicted past year gambling and friend and family subjective norms, attitudes and perceived behavioral control predicted gambling frequency. Intention to gamble mediated these relationships. These findings suggest that college responsible gambling efforts should consider targeting misperceptions of approval regarding gambling behavior (i.e., subjective norms), personal approval of gambling behavior (i.e., attitudes), and perceived behavioral control to better manage gambling behavior in various situations.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/43849672" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="2143696007a7f3931c338adbbf74846f" rel="nofollow" data-download="{"attachment_id":64171685,"asset_id":43849672,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/64171685/download_file?st=MTczOTgwMzc0NSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="166340688" href="https://challiance.academia.edu/SarahNelson">Sarah Nelson</a><script data-card-contents-for-user="166340688" type="text/json">{"id":166340688,"first_name":"Sarah","last_name":"Nelson","domain_name":"challiance","page_name":"SarahNelson","display_name":"Sarah Nelson","profile_url":"https://challiance.academia.edu/SarahNelson?f_ri=62112","photo":"https://gravatar.com/avatar/4c201c9426d57c4c33323e643b77b901?s=65"}</script></span></span></li><li class="js-paper-rank-work_43849672 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="43849672"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 43849672, container: ".js-paper-rank-work_43849672", }); 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$(".js-view-count[data-work-id=43849672]").text(description); $(".js-view-count-work_43849672").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_43849672").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="43849672"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">16</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="2827" rel="nofollow" href="https://www.academia.edu/Documents/in/Mental_Health">Mental Health</a>, <script data-card-contents-for-ri="2827" type="text/json">{"id":2827,"name":"Mental Health","url":"https://www.academia.edu/Documents/in/Mental_Health?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4626" rel="nofollow" href="https://www.academia.edu/Documents/in/Social_Cognition">Social Cognition</a>, <script data-card-contents-for-ri="4626" type="text/json">{"id":4626,"name":"Social Cognition","url":"https://www.academia.edu/Documents/in/Social_Cognition?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="10174" rel="nofollow" href="https://www.academia.edu/Documents/in/Mediation">Mediation</a><script data-card-contents-for-ri="10174" type="text/json">{"id":10174,"name":"Mediation","url":"https://www.academia.edu/Documents/in/Mediation?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=43849672]'), work: {"id":43849672,"title":"Using the theory of planned behavior to predict gambling behavior","created_at":"2020-08-13T06:50:10.953-07:00","url":"https://www.academia.edu/43849672/Using_the_theory_of_planned_behavior_to_predict_gambling_behavior?f_ri=62112","dom_id":"work_43849672","summary":"Gambling is an important public health concern. To better understand gambling behavior, we conducted a classroom-based survey that assessed the role of the theory of planned behavior (TPB; i.e., intentions, subjective norms, perceived behavioral control, and attitudes) in past year gambling and gambling frequency among college students. Results from this research support the utility of the TPB to explain gambling behavior in this population. Specifically, in TPB models to predict gambling behavior, friend and family subjective norms and perceived behavioral control predicted past year gambling and friend and family subjective norms, attitudes and perceived behavioral control predicted gambling frequency. Intention to gamble mediated these relationships. These findings suggest that college responsible gambling efforts should consider targeting misperceptions of approval regarding gambling behavior (i.e., subjective norms), personal approval of gambling behavior (i.e., attitudes), and perceived behavioral control to better manage gambling behavior in various situations.","downloadable_attachments":[{"id":64171685,"asset_id":43849672,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":166340688,"first_name":"Sarah","last_name":"Nelson","domain_name":"challiance","page_name":"SarahNelson","display_name":"Sarah Nelson","profile_url":"https://challiance.academia.edu/SarahNelson?f_ri=62112","photo":"https://gravatar.com/avatar/4c201c9426d57c4c33323e643b77b901?s=65"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=62112","nofollow":true},{"id":2827,"name":"Mental Health","url":"https://www.academia.edu/Documents/in/Mental_Health?f_ri=62112","nofollow":true},{"id":4626,"name":"Social Cognition","url":"https://www.academia.edu/Documents/in/Social_Cognition?f_ri=62112","nofollow":true},{"id":10174,"name":"Mediation","url":"https://www.academia.edu/Documents/in/Mediation?f_ri=62112","nofollow":true},{"id":16288,"name":"Public Health","url":"https://www.academia.edu/Documents/in/Public_Health?f_ri=62112"},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112"},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112"},{"id":67761,"name":"Impulse Control Disorders","url":"https://www.academia.edu/Documents/in/Impulse_Control_Disorders?f_ri=62112"},{"id":92164,"name":"Gambling","url":"https://www.academia.edu/Documents/in/Gambling?f_ri=62112"},{"id":102674,"name":"College Students","url":"https://www.academia.edu/Documents/in/College_Students?f_ri=62112"},{"id":144049,"name":"Attitude","url":"https://www.academia.edu/Documents/in/Attitude?f_ri=62112"},{"id":313857,"name":"Risk Factor","url":"https://www.academia.edu/Documents/in/Risk_Factor?f_ri=62112"},{"id":327850,"name":"Questionnaires","url":"https://www.academia.edu/Documents/in/Questionnaires?f_ri=62112"},{"id":368054,"name":"Perceived Behavioral Control","url":"https://www.academia.edu/Documents/in/Perceived_Behavioral_Control?f_ri=62112"},{"id":598602,"name":"Psychological Theory","url":"https://www.academia.edu/Documents/in/Psychological_Theory?f_ri=62112"},{"id":1318932,"name":"Predictive value of tests","url":"https://www.academia.edu/Documents/in/Predictive_value_of_tests?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_21691463 coauthored" data-work_id="21691463" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/21691463/Biochemical_Parameters_After_Cholecalciferol_Repletion_in_Hemodialysis_Results_From_the_VitaDial_Randomized_Trial">Biochemical Parameters After Cholecalciferol Repletion in Hemodialysis: Results From the VitaDial Randomized Trial</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/21691463" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="4e6c7131ccd75db7540a5da7dea9959d" rel="nofollow" data-download="{"attachment_id":42387199,"asset_id":21691463,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42387199/download_file?st=MTczOTgwMzc0NSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="42859398" href="https://independent.academia.edu/MichelDhaene">Michel Dhaene</a><script data-card-contents-for-user="42859398" type="text/json">{"id":42859398,"first_name":"Michel","last_name":"Dhaene","domain_name":"independent","page_name":"MichelDhaene","display_name":"Michel Dhaene","profile_url":"https://independent.academia.edu/MichelDhaene?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-21691463">+1</span><div class="hidden js-additional-users-21691463"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/AnnickMassart">Annick Massart</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-21691463'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-21691463').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_21691463 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="21691463"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 21691463, container: ".js-paper-rank-work_21691463", }); });</script></li><li class="js-percentile-work_21691463 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 21691463; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_21691463"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_21691463 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="21691463"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 21691463; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=21691463]").text(description); $(".js-view-count-work_21691463").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_21691463").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="21691463"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">7</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="9531" rel="nofollow" href="https://www.academia.edu/Documents/in/Vitamin_D">Vitamin D</a>, <script data-card-contents-for-ri="9531" type="text/json">{"id":9531,"name":"Vitamin D","url":"https://www.academia.edu/Documents/in/Vitamin_D?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a>, <script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="137516" rel="nofollow" href="https://www.academia.edu/Documents/in/Follow-up_studies">Follow-up studies</a>, <script data-card-contents-for-ri="137516" type="text/json">{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" rel="nofollow" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a><script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=21691463]'), work: {"id":21691463,"title":"Biochemical Parameters After Cholecalciferol Repletion in Hemodialysis: Results From the VitaDial Randomized Trial","created_at":"2016-02-08T07:13:34.874-08:00","url":"https://www.academia.edu/21691463/Biochemical_Parameters_After_Cholecalciferol_Repletion_in_Hemodialysis_Results_From_the_VitaDial_Randomized_Trial?f_ri=62112","dom_id":"work_21691463","summary":null,"downloadable_attachments":[{"id":42387199,"asset_id":21691463,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":42859398,"first_name":"Michel","last_name":"Dhaene","domain_name":"independent","page_name":"MichelDhaene","display_name":"Michel Dhaene","profile_url":"https://independent.academia.edu/MichelDhaene?f_ri=62112","photo":"/images/s65_no_pic.png"},{"id":50775730,"first_name":"Annick","last_name":"Massart","domain_name":"independent","page_name":"AnnickMassart","display_name":"Annick Massart","profile_url":"https://independent.academia.edu/AnnickMassart?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":9531,"name":"Vitamin D","url":"https://www.academia.edu/Documents/in/Vitamin_D?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies?f_ri=62112","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112","nofollow":true},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=62112"},{"id":330953,"name":"Longitudinal Studies","url":"https://www.academia.edu/Documents/in/Longitudinal_Studies?f_ri=62112"},{"id":1611680,"name":"Renal Dialysis","url":"https://www.academia.edu/Documents/in/Renal_Dialysis?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_18664894 coauthored" data-work_id="18664894" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/18664894/Age_Related_Differences_in_Biomarkers_of_Acute_Inflammation_During_Hospitalization_for_Sepsis">Age-Related Differences in Biomarkers of Acute Inflammation During Hospitalization for Sepsis</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The authors aimed to evaluate age-related differences in inflammation biomarkers during the first 72 h of hospitalization for sepsis. This was a secondary analysis of a prospective observational cohort of adult patients (n = 855) from 10... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_18664894" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The authors aimed to evaluate age-related differences in inflammation biomarkers during the first 72 h of hospitalization for sepsis. This was a secondary analysis of a prospective observational cohort of adult patients (n = 855) from 10 urban academic emergency departments with confirmed infection and two or more systemic inflammatory response syndrome criteria. Six inflammation-related biomarkers were analyzedVchemokine (CC-motif) ligand-23, C-reactive protein, interleukin-1 receptor antagonist, neutrophil gelatinaseYassociated lipocalin (NGAL), peptidoglycan recognition protein, and tumor necrosis factor receptor-1a (TNFR-1a)Vmeasured at presentation and 3, 6, 12, 24, 48, or 72 h later. The median age was 56 (interquartile range, 43 Y 72) years, and sepsis severity was 38% sepsis, 16% severe sepsis without shock, and 46% septic shock; the overall 30-day mortality was 12%. Older age was associated with higher sepsis severity: 41% of subjects aged 18 to 34 years had severe sepsis or septic shock compared with 71% for those aged 65 years or older (P G 0.001). In longitudinal models adjusting for demographics, comorbidities, and infection source, older age was associated with higher baseline values for chemokine (CC-motif) ligand-23, interleukin-1 receptor antagonist, NGAL, and TNFR-1a (all P G 0.05). However, older adults had higher mean values during the entire 72-h period only for NGAL and TNFR-1a and higher final 72-h values only for TNFR-1a. Adjustment or stratification by sepsis severity did not change the ageinflammation associations. Although older adults had higher levels of inflammation at presentation and an increased incidence of severe sepsis and septic shock, these age-related differences in inflammation largely resolved during the first 72 h of hospitalization.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/18664894" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="816515f3c07f1dc334b5e8b0fc5272c4" rel="nofollow" data-download="{"attachment_id":40189432,"asset_id":18664894,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/40189432/download_file?st=MTczOTgwMzc0NSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="38739872" href="https://independent.academia.edu/JuddHollander">Judd Hollander</a><script data-card-contents-for-user="38739872" type="text/json">{"id":38739872,"first_name":"Judd","last_name":"Hollander","domain_name":"independent","page_name":"JuddHollander","display_name":"Judd Hollander","profile_url":"https://independent.academia.edu/JuddHollander?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-18664894">+1</span><div class="hidden js-additional-users-18664894"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/GoyalMunish">Munish Goyal</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-18664894'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-18664894').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_18664894 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="18664894"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 18664894, container: ".js-paper-rank-work_18664894", }); });</script></li><li class="js-percentile-work_18664894 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 18664894; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_18664894"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_18664894 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="18664894"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 18664894; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=18664894]").text(description); $(".js-view-count-work_18664894").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_18664894").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="18664894"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">11</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a>, <script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="96213" rel="nofollow" href="https://www.academia.edu/Documents/in/Hospitalization">Hospitalization</a>, <script data-card-contents-for-ri="96213" type="text/json">{"id":96213,"name":"Hospitalization","url":"https://www.academia.edu/Documents/in/Hospitalization?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="98404" rel="nofollow" href="https://www.academia.edu/Documents/in/Shock">Shock</a><script data-card-contents-for-ri="98404" type="text/json">{"id":98404,"name":"Shock","url":"https://www.academia.edu/Documents/in/Shock?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=18664894]'), work: {"id":18664894,"title":"Age-Related Differences in Biomarkers of Acute Inflammation During Hospitalization for Sepsis","created_at":"2015-11-19T19:03:53.025-08:00","url":"https://www.academia.edu/18664894/Age_Related_Differences_in_Biomarkers_of_Acute_Inflammation_During_Hospitalization_for_Sepsis?f_ri=62112","dom_id":"work_18664894","summary":"The authors aimed to evaluate age-related differences in inflammation biomarkers during the first 72 h of hospitalization for sepsis. This was a secondary analysis of a prospective observational cohort of adult patients (n = 855) from 10 urban academic emergency departments with confirmed infection and two or more systemic inflammatory response syndrome criteria. Six inflammation-related biomarkers were analyzedVchemokine (CC-motif) ligand-23, C-reactive protein, interleukin-1 receptor antagonist, neutrophil gelatinaseYassociated lipocalin (NGAL), peptidoglycan recognition protein, and tumor necrosis factor receptor-1a (TNFR-1a)Vmeasured at presentation and 3, 6, 12, 24, 48, or 72 h later. The median age was 56 (interquartile range, 43 Y 72) years, and sepsis severity was 38% sepsis, 16% severe sepsis without shock, and 46% septic shock; the overall 30-day mortality was 12%. Older age was associated with higher sepsis severity: 41% of subjects aged 18 to 34 years had severe sepsis or septic shock compared with 71% for those aged 65 years or older (P G 0.001). In longitudinal models adjusting for demographics, comorbidities, and infection source, older age was associated with higher baseline values for chemokine (CC-motif) ligand-23, interleukin-1 receptor antagonist, NGAL, and TNFR-1a (all P G 0.05). However, older adults had higher mean values during the entire 72-h period only for NGAL and TNFR-1a and higher final 72-h values only for TNFR-1a. Adjustment or stratification by sepsis severity did not change the ageinflammation associations. Although older adults had higher levels of inflammation at presentation and an increased incidence of severe sepsis and septic shock, these age-related differences in inflammation largely resolved during the first 72 h of hospitalization.","downloadable_attachments":[{"id":40189432,"asset_id":18664894,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":38739872,"first_name":"Judd","last_name":"Hollander","domain_name":"independent","page_name":"JuddHollander","display_name":"Judd Hollander","profile_url":"https://independent.academia.edu/JuddHollander?f_ri=62112","photo":"/images/s65_no_pic.png"},{"id":39203730,"first_name":"Munish","last_name":"Goyal","domain_name":"independent","page_name":"GoyalMunish","display_name":"Munish Goyal","profile_url":"https://independent.academia.edu/GoyalMunish?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":96213,"name":"Hospitalization","url":"https://www.academia.edu/Documents/in/Hospitalization?f_ri=62112","nofollow":true},{"id":98404,"name":"Shock","url":"https://www.academia.edu/Documents/in/Shock?f_ri=62112","nofollow":true},{"id":125076,"name":"Sepsis","url":"https://www.academia.edu/Documents/in/Sepsis?f_ri=62112"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=62112"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=62112"},{"id":546419,"name":"Age Factors","url":"https://www.academia.edu/Documents/in/Age_Factors?f_ri=62112"},{"id":568482,"name":"Biological markers","url":"https://www.academia.edu/Documents/in/Biological_markers?f_ri=62112"},{"id":901876,"name":"Sensitivity and Specificity","url":"https://www.academia.edu/Documents/in/Sensitivity_and_Specificity?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_22767551" data-work_id="22767551" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/22767551/Patterns_and_Potential_Value_of_Cardiac_Troponin_I_Elevations_After_Pediatric_Cardiac_Operations">Patterns and Potential Value of Cardiac Troponin I Elevations After Pediatric Cardiac Operations</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Background. Perioperative myocardial injury is a major determinant of postoperative cardiac dysfunction for congenital heart disease, but its assessment during this period is difficult. The objective of this study was to determine the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_22767551" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Background. Perioperative myocardial injury is a major determinant of postoperative cardiac dysfunction for congenital heart disease, but its assessment during this period is difficult. The objective of this study was to determine the suitability of using postoperative serum concentrations of cardiac troponin I (cTnI) for this purpose.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/22767551" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="e8542aa3540c9a009b942c40fa58c1b4" rel="nofollow" data-download="{"attachment_id":43325154,"asset_id":22767551,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/43325154/download_file?st=MTczOTgwMzc0NSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="44404398" href="https://independent.academia.edu/MaryWood6">Mary Wood</a><script data-card-contents-for-user="44404398" type="text/json">{"id":44404398,"first_name":"Mary","last_name":"Wood","domain_name":"independent","page_name":"MaryWood6","display_name":"Mary Wood","profile_url":"https://independent.academia.edu/MaryWood6?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_22767551 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="22767551"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 22767551, container: ".js-paper-rank-work_22767551", }); });</script></li><li class="js-percentile-work_22767551 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 22767551; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_22767551"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_22767551 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="22767551"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 22767551; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=22767551]").text(description); $(".js-view-count-work_22767551").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_22767551").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="22767551"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">19</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="8270" rel="nofollow" href="https://www.academia.edu/Documents/in/Forecasting">Forecasting</a>, <script data-card-contents-for-ri="8270" type="text/json">{"id":8270,"name":"Forecasting","url":"https://www.academia.edu/Documents/in/Forecasting?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="57980" rel="nofollow" href="https://www.academia.edu/Documents/in/Congenital_Heart_Defects">Congenital Heart Defects</a>, <script data-card-contents-for-ri="57980" type="text/json">{"id":57980,"name":"Congenital Heart Defects","url":"https://www.academia.edu/Documents/in/Congenital_Heart_Defects?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a>, <script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="64933" rel="nofollow" href="https://www.academia.edu/Documents/in/Child">Child</a><script data-card-contents-for-ri="64933" type="text/json">{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=22767551]'), work: {"id":22767551,"title":"Patterns and Potential Value of Cardiac Troponin I Elevations After Pediatric Cardiac Operations","created_at":"2016-03-03T12:35:08.523-08:00","url":"https://www.academia.edu/22767551/Patterns_and_Potential_Value_of_Cardiac_Troponin_I_Elevations_After_Pediatric_Cardiac_Operations?f_ri=62112","dom_id":"work_22767551","summary":"Background. Perioperative myocardial injury is a major determinant of postoperative cardiac dysfunction for congenital heart disease, but its assessment during this period is difficult. The objective of this study was to determine the suitability of using postoperative serum concentrations of cardiac troponin I (cTnI) for this purpose.","downloadable_attachments":[{"id":43325154,"asset_id":22767551,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":44404398,"first_name":"Mary","last_name":"Wood","domain_name":"independent","page_name":"MaryWood6","display_name":"Mary Wood","profile_url":"https://independent.academia.edu/MaryWood6?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":8270,"name":"Forecasting","url":"https://www.academia.edu/Documents/in/Forecasting?f_ri=62112","nofollow":true},{"id":57980,"name":"Congenital Heart Defects","url":"https://www.academia.edu/Documents/in/Congenital_Heart_Defects?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=62112","nofollow":true},{"id":94234,"name":"INTENSIVE CARE","url":"https://www.academia.edu/Documents/in/INTENSIVE_CARE?f_ri=62112"},{"id":96213,"name":"Hospitalization","url":"https://www.academia.edu/Documents/in/Hospitalization?f_ri=62112"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=62112"},{"id":211917,"name":"Length of Stay","url":"https://www.academia.edu/Documents/in/Length_of_Stay?f_ri=62112"},{"id":240716,"name":"Body Temperature","url":"https://www.academia.edu/Documents/in/Body_Temperature?f_ri=62112"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112"},{"id":392828,"name":"Myocardium","url":"https://www.academia.edu/Documents/in/Myocardium?f_ri=62112"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=62112"},{"id":489727,"name":"Prognosis","url":"https://www.academia.edu/Documents/in/Prognosis?f_ri=62112"},{"id":735030,"name":"Congenital Heart Disease","url":"https://www.academia.edu/Documents/in/Congenital_Heart_Disease?f_ri=62112"},{"id":759360,"name":"Ventricular Septal Defect","url":"https://www.academia.edu/Documents/in/Ventricular_Septal_Defect?f_ri=62112"},{"id":1309695,"name":"Troponin I","url":"https://www.academia.edu/Documents/in/Troponin_I?f_ri=62112"},{"id":1325909,"name":"Atrial Septal Defect","url":"https://www.academia.edu/Documents/in/Atrial_Septal_Defect?f_ri=62112"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=62112"},{"id":2363093,"name":"Cardiopulmonary bypass","url":"https://www.academia.edu/Documents/in/Cardiopulmonary_bypass?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_25133691" data-work_id="25133691" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/25133691/Management_of_drooling_in_disabled_patients_with_scopolamine_patches">Management of drooling in disabled patients with scopolamine patches</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">• Drooling is a common problem in disabled individuals and has significant physical, psychosocial and aesthetic repercussions. Scopolamine has been used to treat drooling in a number of medical specialities, including otorhinolaryngology,... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_25133691" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">• Drooling is a common problem in disabled individuals and has significant physical, psychosocial and aesthetic repercussions. Scopolamine has been used to treat drooling in a number of medical specialities, including otorhinolaryngology, neurology and palliative care. This study evaluates the efficacy of this treatment in severely disabled patients.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/25133691" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="7592c83f22005d7c85c2e787d99ec01d" rel="nofollow" data-download="{"attachment_id":45454500,"asset_id":25133691,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45454500/download_file?st=MTczOTgwMzc0NSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="48414048" href="https://independent.academia.edu/JacoboLimeres">Jacobo Limeres</a><script data-card-contents-for-user="48414048" type="text/json">{"id":48414048,"first_name":"Jacobo","last_name":"Limeres","domain_name":"independent","page_name":"JacoboLimeres","display_name":"Jacobo Limeres","profile_url":"https://independent.academia.edu/JacoboLimeres?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_25133691 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="25133691"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 25133691, container: ".js-paper-rank-work_25133691", }); 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Scopolamine has been used to treat drooling in a number of medical specialities, including otorhinolaryngology, neurology and palliative care. This study evaluates the efficacy of this treatment in severely disabled patients.","downloadable_attachments":[{"id":45454500,"asset_id":25133691,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":48414048,"first_name":"Jacobo","last_name":"Limeres","domain_name":"independent","page_name":"JacoboLimeres","display_name":"Jacobo Limeres","profile_url":"https://independent.academia.edu/JacoboLimeres?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=62112","nofollow":true},{"id":133057,"name":"Young 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whiplash-associated disorders: a prospective randomised study</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">The study findings will help improve the treatment of patients with chronic WAD.</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/15173785" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="32434c0875ca9887d88b7a8705ad396a" rel="nofollow" data-download="{"attachment_id":43500198,"asset_id":15173785,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" 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class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/3445844/Does_Prior_Short_Segment_Surgery_for_Adult_Scoliosis_Impact_Clinical_Outcome_Among_Patients_Undergoing_Scoliosis_Correction_930">Does Prior Short-Segment Surgery for Adult Scoliosis Impact Clinical Outcome Among Patients Undergoing Scoliosis Correction?: 930</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/3445844" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="29ad2755090cb57836defb63daa875aa" rel="nofollow" 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type="text/json">{"id":650,"name":"Neurosurgery","url":"https://www.academia.edu/Documents/in/Neurosurgery?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="12426" rel="nofollow" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a>, <script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a><script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=3445844]'), work: {"id":3445844,"title":"Does Prior Short-Segment Surgery for Adult Scoliosis Impact Clinical Outcome Among Patients Undergoing Scoliosis Correction?: 930","created_at":"2013-05-02T00:41:09.438-07:00","url":"https://www.academia.edu/3445844/Does_Prior_Short_Segment_Surgery_for_Adult_Scoliosis_Impact_Clinical_Outcome_Among_Patients_Undergoing_Scoliosis_Correction_930?f_ri=62112","dom_id":"work_3445844","summary":null,"downloadable_attachments":[{"id":50278562,"asset_id":3445844,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":4022974,"first_name":"Virginie","last_name":"Lafage","domain_name":"independent","page_name":"VirginieLafage","display_name":"Virginie Lafage","profile_url":"https://independent.academia.edu/VirginieLafage?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery?f_ri=62112","nofollow":true},{"id":650,"name":"Neurosurgery","url":"https://www.academia.edu/Documents/in/Neurosurgery?f_ri=62112","nofollow":true},{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":63890,"name":"Complication","url":"https://www.academia.edu/Documents/in/Complication?f_ri=62112"},{"id":65256,"name":"Outcome","url":"https://www.academia.edu/Documents/in/Outcome?f_ri=62112"},{"id":209856,"name":"Registries","url":"https://www.academia.edu/Documents/in/Registries?f_ri=62112"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112"},{"id":457827,"name":"Scoliosis","url":"https://www.academia.edu/Documents/in/Scoliosis?f_ri=62112"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=62112"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=62112"},{"id":1315242,"name":"Spinal Fusion","url":"https://www.academia.edu/Documents/in/Spinal_Fusion?f_ri=62112"},{"id":1330117,"name":"Orthopedic Procedures","url":"https://www.academia.edu/Documents/in/Orthopedic_Procedures?f_ri=62112"},{"id":2463800,"name":"Severity of Illness Index","url":"https://www.academia.edu/Documents/in/Severity_of_Illness_Index?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_19384514 coauthored" data-work_id="19384514" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/19384514/Development_of_a_short_form_of_the_Severe_Impairment_Battery">Development of a short form of the Severe Impairment Battery</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The authors sought to develop a short form of the Severe Impairment Battery (SIB). Methods: Authors describe the development of an empirically-derived short form of the SIB (SIB-S) by use of data from 191 subjects with severe dementia in... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_19384514" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The authors sought to develop a short form of the Severe Impairment Battery (SIB). Methods: Authors describe the development of an empirically-derived short form of the SIB (SIB-S) by use of data from 191 subjects with severe dementia in the United States and France. Results: Mean (standard deviation) Mini-Mental State Exam scores for the American and French samples were 7.7 (4.8) and 5.7 (3.4), respectively, and original SIB scores were 71.87 (18.34) and 58.38 (26.86), respectively. Exploratory factor analyses were conducted separately and in combination for the two samples, to determine the number of clinically meaningful factors. An eightfactor model, explaining 60.2% of the common variance, was selected. The eight constructs were described as: expressive language, memory (verbal and nonverbal), social interaction, color-naming, praxis, reading and writing, fluency, and attention. Derived SIB-S scores were 38.41 (9.12) and 29.79 (13.17) for the American and French samples, respectively. Conclusions: The original SIB is a valid and reliable research tool developed to enable reliable assessment of patients with severe dementia; it takes approximately 30 minutes to administer. The SIB-S takes only 10-15 minutes to administer, making it more appropriate for use in patients with very severe dementia, while it maintains the attributes of the original SIB. (Am J Geriatr Psychiatry 2005; 13:-)</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/19384514" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="c7aad70dc6a30e025a07c361223eb8f1" rel="nofollow" data-download="{"attachment_id":40590143,"asset_id":19384514,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/40590143/download_file?st=MTczOTgwMzc0NSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="39647754" href="https://independent.academia.edu/KariKastango">Kari Kastango</a><script data-card-contents-for-user="39647754" type="text/json">{"id":39647754,"first_name":"Kari","last_name":"Kastango","domain_name":"independent","page_name":"KariKastango","display_name":"Kari Kastango","profile_url":"https://independent.academia.edu/KariKastango?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-19384514">+1</span><div class="hidden js-additional-users-19384514"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/BrucePollock3">Bruce Pollock</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-19384514'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-19384514').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_19384514 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="19384514"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 19384514, container: ".js-paper-rank-work_19384514", }); });</script></li><li class="js-percentile-work_19384514 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 19384514; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_19384514"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_19384514 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="19384514"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 19384514; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=19384514]").text(description); $(".js-view-count-work_19384514").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_19384514").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="19384514"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">14</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="2599" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychometrics">Psychometrics</a>, <script data-card-contents-for-ri="2599" type="text/json">{"id":2599,"name":"Psychometrics","url":"https://www.academia.edu/Documents/in/Psychometrics?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="3662" rel="nofollow" href="https://www.academia.edu/Documents/in/Dementia">Dementia</a>, <script data-card-contents-for-ri="3662" type="text/json">{"id":3662,"name":"Dementia","url":"https://www.academia.edu/Documents/in/Dementia?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="27336" rel="nofollow" href="https://www.academia.edu/Documents/in/France">France</a>, <script data-card-contents-for-ri="27336" type="text/json">{"id":27336,"name":"France","url":"https://www.academia.edu/Documents/in/France?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="57511" rel="nofollow" href="https://www.academia.edu/Documents/in/Cross-Cultural_Comparison">Cross-Cultural Comparison</a><script data-card-contents-for-ri="57511" type="text/json">{"id":57511,"name":"Cross-Cultural Comparison","url":"https://www.academia.edu/Documents/in/Cross-Cultural_Comparison?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=19384514]'), work: {"id":19384514,"title":"Development of a short form of the Severe Impairment Battery","created_at":"2015-12-02T15:53:22.089-08:00","url":"https://www.academia.edu/19384514/Development_of_a_short_form_of_the_Severe_Impairment_Battery?f_ri=62112","dom_id":"work_19384514","summary":"The authors sought to develop a short form of the Severe Impairment Battery (SIB). Methods: Authors describe the development of an empirically-derived short form of the SIB (SIB-S) by use of data from 191 subjects with severe dementia in the United States and France. Results: Mean (standard deviation) Mini-Mental State Exam scores for the American and French samples were 7.7 (4.8) and 5.7 (3.4), respectively, and original SIB scores were 71.87 (18.34) and 58.38 (26.86), respectively. Exploratory factor analyses were conducted separately and in combination for the two samples, to determine the number of clinically meaningful factors. An eightfactor model, explaining 60.2% of the common variance, was selected. The eight constructs were described as: expressive language, memory (verbal and nonverbal), social interaction, color-naming, praxis, reading and writing, fluency, and attention. Derived SIB-S scores were 38.41 (9.12) and 29.79 (13.17) for the American and French samples, respectively. Conclusions: The original SIB is a valid and reliable research tool developed to enable reliable assessment of patients with severe dementia; it takes approximately 30 minutes to administer. The SIB-S takes only 10-15 minutes to administer, making it more appropriate for use in patients with very severe dementia, while it maintains the attributes of the original SIB. (Am J Geriatr Psychiatry 2005; 13:-)","downloadable_attachments":[{"id":40590143,"asset_id":19384514,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":39647754,"first_name":"Kari","last_name":"Kastango","domain_name":"independent","page_name":"KariKastango","display_name":"Kari Kastango","profile_url":"https://independent.academia.edu/KariKastango?f_ri=62112","photo":"/images/s65_no_pic.png"},{"id":65487503,"first_name":"Bruce","last_name":"Pollock","domain_name":"independent","page_name":"BrucePollock3","display_name":"Bruce Pollock","profile_url":"https://independent.academia.edu/BrucePollock3?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":2599,"name":"Psychometrics","url":"https://www.academia.edu/Documents/in/Psychometrics?f_ri=62112","nofollow":true},{"id":3662,"name":"Dementia","url":"https://www.academia.edu/Documents/in/Dementia?f_ri=62112","nofollow":true},{"id":27336,"name":"France","url":"https://www.academia.edu/Documents/in/France?f_ri=62112","nofollow":true},{"id":57511,"name":"Cross-Cultural Comparison","url":"https://www.academia.edu/Documents/in/Cross-Cultural_Comparison?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112"},{"id":98134,"name":"United States","url":"https://www.academia.edu/Documents/in/United_States?f_ri=62112"},{"id":151448,"name":"American","url":"https://www.academia.edu/Documents/in/American?f_ri=62112"},{"id":163143,"name":"STEM (short form)","url":"https://www.academia.edu/Documents/in/STEM_short_form_?f_ri=62112"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=62112"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=62112"},{"id":549280,"name":"Reproducibility of Results","url":"https://www.academia.edu/Documents/in/Reproducibility_of_Results?f_ri=62112"},{"id":1120234,"name":"Alzheimer Disease","url":"https://www.academia.edu/Documents/in/Alzheimer_Disease?f_ri=62112"},{"id":1627527,"name":"Cognition disorders","url":"https://www.academia.edu/Documents/in/Cognition_disorders?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_22216199" data-work_id="22216199" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/22216199/Assessment_of_the_intrinsic_urethral_sphincter_component_function_in_postprostatectomy_urinary_incontinence">Assessment of the intrinsic urethral sphincter component function in postprostatectomy urinary incontinence</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Postprostatectomy incontinence remains a disabling condition. Sphincter injury, detrusor instability, and decreased bladder compliance have been previously reported as major factors. The aim of this study was to evaluate the urethral... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_22216199" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Postprostatectomy incontinence remains a disabling condition. Sphincter injury, detrusor instability, and decreased bladder compliance have been previously reported as major factors. The aim of this study was to evaluate the urethral sphincter intrinsic component, which may provide passive continence. A urodynamic evaluation was performed in 20 patients undergoing a radical retropubic prostatectomy in the preoperative period and 3 months after surgery. Patients with disabled urinary incontinence underwent a new urodynamic evaluation 6 months later. The urethral pressure pro¢le was measured just before, then 10, 20, and 30 minutes after the injection of 0.5 mg/kg moxisylyte chlorhydrate, an alpha adrenergic blocker. Three di¡erent pressure components were de¢ned in urethral sphincter capacity: baseline, adrenergic, and voluntary. A postoperative intrinsic urethral sphincter pressure component was found in 17 patients and its value was under 6 cm H 2 O in ¢ve cases of severe incontinence. No signi¢cant di¡erence was observed for these patients on urethral pro¢le components 6 months later. In contrast, in cases of signi¢cant intrinsic component value, no incontinence was observed in most patients. Passive continence after radical prostatectomy should be a matter of concern and may also explain paradoxical incontinence, despite high voluntary urethral pressure obtained after reeducation. A follow-up evaluation of the intrinsic sphincter component is suggested, by using an alpha receptor blockage test during urodynamic studies in the management of patients with postprostatectomy incontinence.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/22216199" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="2f2e8701632eacf418f54cdb13595319" rel="nofollow" data-download="{"attachment_id":42869116,"asset_id":22216199,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42869116/download_file?st=MTczOTgwMzc0NSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="43576862" href="https://georouen.academia.edu/HubertBugel">Hubert Bugel</a><script data-card-contents-for-user="43576862" type="text/json">{"id":43576862,"first_name":"Hubert","last_name":"Bugel","domain_name":"georouen","page_name":"HubertBugel","display_name":"Hubert Bugel","profile_url":"https://georouen.academia.edu/HubertBugel?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_22216199 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="22216199"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 22216199, container: ".js-paper-rank-work_22216199", }); });</script></li><li class="js-percentile-work_22216199 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 22216199; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_22216199"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_22216199 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="22216199"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 22216199; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=22216199]").text(description); $(".js-view-count-work_22216199").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_22216199").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="22216199"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">8</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="54217" rel="nofollow" href="https://www.academia.edu/Documents/in/Urinary_incontinence">Urinary incontinence</a>, <script data-card-contents-for-ri="54217" type="text/json">{"id":54217,"name":"Urinary incontinence","url":"https://www.academia.edu/Documents/in/Urinary_incontinence?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a>, <script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="131549" rel="nofollow" href="https://www.academia.edu/Documents/in/Urodynamics">Urodynamics</a>, <script data-card-contents-for-ri="131549" type="text/json">{"id":131549,"name":"Urodynamics","url":"https://www.academia.edu/Documents/in/Urodynamics?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" rel="nofollow" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a><script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=22216199]'), work: {"id":22216199,"title":"Assessment of the intrinsic urethral sphincter component function in postprostatectomy urinary incontinence","created_at":"2016-02-20T05:19:10.344-08:00","url":"https://www.academia.edu/22216199/Assessment_of_the_intrinsic_urethral_sphincter_component_function_in_postprostatectomy_urinary_incontinence?f_ri=62112","dom_id":"work_22216199","summary":"Postprostatectomy incontinence remains a disabling condition. Sphincter injury, detrusor instability, and decreased bladder compliance have been previously reported as major factors. The aim of this study was to evaluate the urethral sphincter intrinsic component, which may provide passive continence. A urodynamic evaluation was performed in 20 patients undergoing a radical retropubic prostatectomy in the preoperative period and 3 months after surgery. Patients with disabled urinary incontinence underwent a new urodynamic evaluation 6 months later. The urethral pressure pro¢le was measured just before, then 10, 20, and 30 minutes after the injection of 0.5 mg/kg moxisylyte chlorhydrate, an alpha adrenergic blocker. Three di¡erent pressure components were de¢ned in urethral sphincter capacity: baseline, adrenergic, and voluntary. A postoperative intrinsic urethral sphincter pressure component was found in 17 patients and its value was under 6 cm H 2 O in ¢ve cases of severe incontinence. No signi¢cant di¡erence was observed for these patients on urethral pro¢le components 6 months later. In contrast, in cases of signi¢cant intrinsic component value, no incontinence was observed in most patients. Passive continence after radical prostatectomy should be a matter of concern and may also explain paradoxical incontinence, despite high voluntary urethral pressure obtained after reeducation. A follow-up evaluation of the intrinsic sphincter component is suggested, by using an alpha receptor blockage test during urodynamic studies in the management of patients with postprostatectomy incontinence.","downloadable_attachments":[{"id":42869116,"asset_id":22216199,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":43576862,"first_name":"Hubert","last_name":"Bugel","domain_name":"georouen","page_name":"HubertBugel","display_name":"Hubert Bugel","profile_url":"https://georouen.academia.edu/HubertBugel?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":54217,"name":"Urinary incontinence","url":"https://www.academia.edu/Documents/in/Urinary_incontinence?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":131549,"name":"Urodynamics","url":"https://www.academia.edu/Documents/in/Urodynamics?f_ri=62112","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112","nofollow":true},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=62112"},{"id":291038,"name":"Pressure","url":"https://www.academia.edu/Documents/in/Pressure?f_ri=62112"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=62112"},{"id":1416160,"name":"Neurourology","url":"https://www.academia.edu/Documents/in/Neurourology?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_14272115" data-work_id="14272115" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/14272115/Saphenofemoral_arteriovenous_fistula_as_hemodialysis_access">Saphenofemoral arteriovenous fistula as hemodialysis access</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Background: An upper limb arteriovenous (AV) fistula is the access of choice for haemodialysis (HD). There have been few reports of saphenofemoral AV fistulas (SFAVF) over the last 10-20 years because of previous suggestions of poor... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_14272115" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Background: An upper limb arteriovenous (AV) fistula is the access of choice for haemodialysis (HD). There have been few reports of saphenofemoral AV fistulas (SFAVF) over the last 10-20 years because of previous suggestions of poor patencies and needling difficulties. Here, we describe our clinical experience with SFAVF.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/14272115" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="e50dd553c223ee999ed7978932e0b7e6" rel="nofollow" data-download="{"attachment_id":44369192,"asset_id":14272115,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44369192/download_file?st=MTczOTgwMzc0NSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="15915765" href="https://independent.academia.edu/VitorValenti">Vitor Valenti</a><script data-card-contents-for-user="15915765" type="text/json">{"id":15915765,"first_name":"Vitor","last_name":"Valenti","domain_name":"independent","page_name":"VitorValenti","display_name":"Vitor Valenti","profile_url":"https://independent.academia.edu/VitorValenti?f_ri=62112","photo":"https://0.academia-photos.com/15915765/9848608/10976932/s65_vitor.valenti.jpg_oh_12cb6e9e8c9534b04bc0b0c881e4bfc0_oe_56492149___gda___1443869733_248a8e9865012ccc14ade346fe65cf6d"}</script></span></span></li><li class="js-paper-rank-work_14272115 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="14272115"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 14272115, container: ".js-paper-rank-work_14272115", }); });</script></li><li class="js-percentile-work_14272115 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14272115; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_14272115"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_14272115 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="14272115"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14272115; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14272115]").text(description); $(".js-view-count-work_14272115").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_14272115").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="14272115"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a>, <script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="101212" rel="nofollow" href="https://www.academia.edu/Documents/in/Hemodialysis">Hemodialysis</a>, <script data-card-contents-for-ri="101212" type="text/json">{"id":101212,"name":"Hemodialysis","url":"https://www.academia.edu/Documents/in/Hemodialysis?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="172673" rel="nofollow" href="https://www.academia.edu/Documents/in/Haemodialysis">Haemodialysis</a>, <script data-card-contents-for-ri="172673" type="text/json">{"id":172673,"name":"Haemodialysis","url":"https://www.academia.edu/Documents/in/Haemodialysis?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" rel="nofollow" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a><script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=14272115]'), work: {"id":14272115,"title":"Saphenofemoral arteriovenous fistula as hemodialysis access","created_at":"2015-07-21T16:31:24.462-07:00","url":"https://www.academia.edu/14272115/Saphenofemoral_arteriovenous_fistula_as_hemodialysis_access?f_ri=62112","dom_id":"work_14272115","summary":"Background: An upper limb arteriovenous (AV) fistula is the access of choice for haemodialysis (HD). There have been few reports of saphenofemoral AV fistulas (SFAVF) over the last 10-20 years because of previous suggestions of poor patencies and needling difficulties. Here, we describe our clinical experience with SFAVF.","downloadable_attachments":[{"id":44369192,"asset_id":14272115,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":15915765,"first_name":"Vitor","last_name":"Valenti","domain_name":"independent","page_name":"VitorValenti","display_name":"Vitor Valenti","profile_url":"https://independent.academia.edu/VitorValenti?f_ri=62112","photo":"https://0.academia-photos.com/15915765/9848608/10976932/s65_vitor.valenti.jpg_oh_12cb6e9e8c9534b04bc0b0c881e4bfc0_oe_56492149___gda___1443869733_248a8e9865012ccc14ade346fe65cf6d"}],"research_interests":[{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":101212,"name":"Hemodialysis","url":"https://www.academia.edu/Documents/in/Hemodialysis?f_ri=62112","nofollow":true},{"id":172673,"name":"Haemodialysis","url":"https://www.academia.edu/Documents/in/Haemodialysis?f_ri=62112","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112","nofollow":true},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=62112"},{"id":561992,"name":"Postoperative Complication","url":"https://www.academia.edu/Documents/in/Postoperative_Complication?f_ri=62112"},{"id":788697,"name":"SAPHENOUS VEIN","url":"https://www.academia.edu/Documents/in/SAPHENOUS_VEIN?f_ri=62112"},{"id":963781,"name":"Upper Limb","url":"https://www.academia.edu/Documents/in/Upper_Limb?f_ri=62112"},{"id":1611680,"name":"Renal Dialysis","url":"https://www.academia.edu/Documents/in/Renal_Dialysis?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_16499219 coauthored" data-work_id="16499219" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/16499219/Immobility_a_major_risk_factor_for_development_of_pressure_ulcers_among_adult_hospitalized_patients_a_prospective_study">Immobility - a major risk factor for development of pressure ulcers among adult hospitalized patients: a prospective study</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objective: To identify risk factors associated with pressure ulcer development among adult hospitalized medical and surgical patients. Design: A prospective comparative study including 530 adult patients from medical and surgical wards.... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_16499219" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objective: To identify risk factors associated with pressure ulcer development among adult hospitalized medical and surgical patients. Design: A prospective comparative study including 530 adult patients from medical and surgical wards. Registered Nurses made the data collection on admission and once a week for up to 12 weeks. The risk assessment scale used was the Risk Assessment Pressure Sore (RAPS) scale, including the following variables; general physical condition, activity, mobility, moisture, food intake, fluid intake, sensory perception, friction and shear, body temperature and serum albumin. Results: Sixty-two (11.7%) patients developed 85 pressure ulcers. The most common pressure ulcer was that of nonblanchable erythema. Patients who developed pressure ulcers were significantly older, hospitalized for a longer time, had lower scores on the total RAPS scale, had lower weight and lower diastolic blood pressure than nonpressure ulcer patients did. In the multiple logistic regression analyses using variables included in the RAPS scale immobility emerged as a strong risk factor. When adding remaining significant variables in the analyses, mobility, time of hospitalization, age, surgical treatment and weight were found to be risk factors for pressure ulcer development. Conclusion: It is confirmed that immobility is a risk factor of major importance for pressure ulcer development among adult hospitalized patients. The results also indicate that the RAPS scale may be useful for prediction of pressure ulcer development in clinical practice.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/16499219" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="c5136205a2e6962604598982123b8aa6" rel="nofollow" data-download="{"attachment_id":42497281,"asset_id":16499219,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42497281/download_file?st=MTczOTgwMzc0NSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="35729560" href="https://independent.academia.edu/LindgrenMargareta">Margareta Lindgren</a><script data-card-contents-for-user="35729560" type="text/json">{"id":35729560,"first_name":"Margareta","last_name":"Lindgren","domain_name":"independent","page_name":"LindgrenMargareta","display_name":"Margareta Lindgren","profile_url":"https://independent.academia.edu/LindgrenMargareta?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-16499219">+1</span><div class="hidden js-additional-users-16499219"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://liu-se.academia.edu/MatsFredrikson">Mats Fredrikson</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-16499219'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-16499219').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_16499219 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="16499219"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 16499219, container: ".js-paper-rank-work_16499219", }); });</script></li><li class="js-percentile-work_16499219 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 16499219; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_16499219"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_16499219 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="16499219"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 16499219; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=16499219]").text(description); $(".js-view-count-work_16499219").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_16499219").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="16499219"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">19</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="588" rel="nofollow" href="https://www.academia.edu/Documents/in/Nursing">Nursing</a>, <script data-card-contents-for-ri="588" type="text/json">{"id":588,"name":"Nursing","url":"https://www.academia.edu/Documents/in/Nursing?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="16664" rel="nofollow" href="https://www.academia.edu/Documents/in/Risk_assessment">Risk assessment</a>, <script data-card-contents-for-ri="16664" type="text/json">{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="44529" rel="nofollow" href="https://www.academia.edu/Documents/in/Activities_of_Daily_Living">Activities of Daily Living</a>, <script data-card-contents-for-ri="44529" type="text/json">{"id":44529,"name":"Activities of Daily Living","url":"https://www.academia.edu/Documents/in/Activities_of_Daily_Living?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="44814" rel="nofollow" href="https://www.academia.edu/Documents/in/Sweden">Sweden</a><script data-card-contents-for-ri="44814" type="text/json">{"id":44814,"name":"Sweden","url":"https://www.academia.edu/Documents/in/Sweden?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=16499219]'), work: {"id":16499219,"title":"Immobility - a major risk factor for development of pressure ulcers among adult hospitalized patients: a prospective study","created_at":"2015-10-06T00:37:27.614-07:00","url":"https://www.academia.edu/16499219/Immobility_a_major_risk_factor_for_development_of_pressure_ulcers_among_adult_hospitalized_patients_a_prospective_study?f_ri=62112","dom_id":"work_16499219","summary":"Objective: To identify risk factors associated with pressure ulcer development among adult hospitalized medical and surgical patients. Design: A prospective comparative study including 530 adult patients from medical and surgical wards. Registered Nurses made the data collection on admission and once a week for up to 12 weeks. The risk assessment scale used was the Risk Assessment Pressure Sore (RAPS) scale, including the following variables; general physical condition, activity, mobility, moisture, food intake, fluid intake, sensory perception, friction and shear, body temperature and serum albumin. Results: Sixty-two (11.7%) patients developed 85 pressure ulcers. The most common pressure ulcer was that of nonblanchable erythema. Patients who developed pressure ulcers were significantly older, hospitalized for a longer time, had lower scores on the total RAPS scale, had lower weight and lower diastolic blood pressure than nonpressure ulcer patients did. In the multiple logistic regression analyses using variables included in the RAPS scale immobility emerged as a strong risk factor. When adding remaining significant variables in the analyses, mobility, time of hospitalization, age, surgical treatment and weight were found to be risk factors for pressure ulcer development. Conclusion: It is confirmed that immobility is a risk factor of major importance for pressure ulcer development among adult hospitalized patients. The results also indicate that the RAPS scale may be useful for prediction of pressure ulcer development in clinical practice.","downloadable_attachments":[{"id":42497281,"asset_id":16499219,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":35729560,"first_name":"Margareta","last_name":"Lindgren","domain_name":"independent","page_name":"LindgrenMargareta","display_name":"Margareta Lindgren","profile_url":"https://independent.academia.edu/LindgrenMargareta?f_ri=62112","photo":"/images/s65_no_pic.png"},{"id":36055279,"first_name":"Mats","last_name":"Fredrikson","domain_name":"liu-se","page_name":"MatsFredrikson","display_name":"Mats Fredrikson","profile_url":"https://liu-se.academia.edu/MatsFredrikson?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":588,"name":"Nursing","url":"https://www.academia.edu/Documents/in/Nursing?f_ri=62112","nofollow":true},{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=62112","nofollow":true},{"id":44529,"name":"Activities of Daily Living","url":"https://www.academia.edu/Documents/in/Activities_of_Daily_Living?f_ri=62112","nofollow":true},{"id":44814,"name":"Sweden","url":"https://www.academia.edu/Documents/in/Sweden?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=62112"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=62112"},{"id":329158,"name":"Caring","url":"https://www.academia.edu/Documents/in/Caring?f_ri=62112"},{"id":413194,"name":"Analysis of Variance","url":"https://www.academia.edu/Documents/in/Analysis_of_Variance?f_ri=62112"},{"id":465839,"name":"Bed Rest","url":"https://www.academia.edu/Documents/in/Bed_Rest?f_ri=62112"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=62112"},{"id":622589,"name":"Risk Assessment","url":"https://www.academia.edu/Documents/in/Risk_Assessment-2?f_ri=62112"},{"id":687277,"name":"Pressure Ulcer","url":"https://www.academia.edu/Documents/in/Pressure_Ulcer?f_ri=62112"},{"id":784431,"name":"Nursing Assessment","url":"https://www.academia.edu/Documents/in/Nursing_Assessment?f_ri=62112"},{"id":854662,"name":"Inpatients","url":"https://www.academia.edu/Documents/in/Inpatients?f_ri=62112"},{"id":1154231,"name":"Immobilization","url":"https://www.academia.edu/Documents/in/Immobilization?f_ri=62112"},{"id":1294607,"name":"Logistic Models","url":"https://www.academia.edu/Documents/in/Logistic_Models?f_ri=62112"},{"id":1312754,"name":"Prospective Study","url":"https://www.academia.edu/Documents/in/Prospective_Study?f_ri=62112"},{"id":1318932,"name":"Predictive value of tests","url":"https://www.academia.edu/Documents/in/Predictive_value_of_tests?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_20080336" data-work_id="20080336" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/20080336/Intensified_therapy_in_acute_lymphoblastic_and_acute_undifferentiated_leukemia_in_adults">Intensified therapy in acute lymphoblastic and acute undifferentiated leukemia in adults</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">One hundred seventy adult patients with acute lymphoblastic leukemia (ALL) or acute undifferentiated leukemia (AUL) were entered into a prospective multicenter therapy trial at 25 hospitals. The aim of the trial was to improve remission... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_20080336" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">One hundred seventy adult patients with acute lymphoblastic leukemia (ALL) or acute undifferentiated leukemia (AUL) were entered into a prospective multicenter therapy trial at 25 hospitals. The aim of the trial was to improve remission duration by using a modified form of an intensified induction regimen that was successful in childhood ALL, to define immunologic subtypes of ALL by use of cell-surface markers, and to extract other possible prognostic factors. The overall complete remission rate was 77.8%. The median overall survival time was 26 months, being 4 months for nonresponders and 32 months for responders. The median remission duration for the 126 patients with complete remission was 20 months. Prognostically favorable factors for remission duration were response to chemotherapy within 4 weeks, age less than 35 years, a low initial leukocyte count, and the immunologic subtypes c-ALL with early response to therapy and T-ALL, where 61% and 58%, respectively, are still in comp...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/20080336" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="f5195a8ee9f1836abea42aba9dfe76c2" rel="nofollow" data-download="{"attachment_id":41249728,"asset_id":20080336,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/41249728/download_file?st=MTczOTgwMzc0NSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="41080518" href="https://uthsc.academia.edu/ArthurNienhuis">Arthur Nienhuis</a><script data-card-contents-for-user="41080518" type="text/json">{"id":41080518,"first_name":"Arthur","last_name":"Nienhuis","domain_name":"uthsc","page_name":"ArthurNienhuis","display_name":"Arthur Nienhuis","profile_url":"https://uthsc.academia.edu/ArthurNienhuis?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_20080336 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="20080336"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 20080336, container: ".js-paper-rank-work_20080336", }); 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$(".js-view-count[data-work-id=20080336]").text(description); $(".js-view-count-work_20080336").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_20080336").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="20080336"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">10</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="14109" rel="nofollow" href="https://www.academia.edu/Documents/in/Leukemia">Leukemia</a>, <script data-card-contents-for-ri="14109" type="text/json">{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a>, <script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="100732" rel="nofollow" href="https://www.academia.edu/Documents/in/Blood">Blood</a><script data-card-contents-for-ri="100732" type="text/json">{"id":100732,"name":"Blood","url":"https://www.academia.edu/Documents/in/Blood?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=20080336]'), work: {"id":20080336,"title":"Intensified therapy in acute lymphoblastic and acute undifferentiated leukemia in adults","created_at":"2016-01-07T05:48:58.029-08:00","url":"https://www.academia.edu/20080336/Intensified_therapy_in_acute_lymphoblastic_and_acute_undifferentiated_leukemia_in_adults?f_ri=62112","dom_id":"work_20080336","summary":"One hundred seventy adult patients with acute lymphoblastic leukemia (ALL) or acute undifferentiated leukemia (AUL) were entered into a prospective multicenter therapy trial at 25 hospitals. The aim of the trial was to improve remission duration by using a modified form of an intensified induction regimen that was successful in childhood ALL, to define immunologic subtypes of ALL by use of cell-surface markers, and to extract other possible prognostic factors. The overall complete remission rate was 77.8%. The median overall survival time was 26 months, being 4 months for nonresponders and 32 months for responders. The median remission duration for the 126 patients with complete remission was 20 months. Prognostically favorable factors for remission duration were response to chemotherapy within 4 weeks, age less than 35 years, a low initial leukocyte count, and the immunologic subtypes c-ALL with early response to therapy and T-ALL, where 61% and 58%, respectively, are still in comp...","downloadable_attachments":[{"id":41249728,"asset_id":20080336,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":41080518,"first_name":"Arthur","last_name":"Nienhuis","domain_name":"uthsc","page_name":"ArthurNienhuis","display_name":"Arthur Nienhuis","profile_url":"https://uthsc.academia.edu/ArthurNienhuis?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":14109,"name":"Leukemia","url":"https://www.academia.edu/Documents/in/Leukemia?f_ri=62112","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":100732,"name":"Blood","url":"https://www.academia.edu/Documents/in/Blood?f_ri=62112","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112"},{"id":280237,"name":"T lymphocytes","url":"https://www.academia.edu/Documents/in/T_lymphocytes?f_ri=62112"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=62112"},{"id":546419,"name":"Age Factors","url":"https://www.academia.edu/Documents/in/Age_Factors?f_ri=62112"},{"id":678853,"name":"B Lymphocytes","url":"https://www.academia.edu/Documents/in/B_Lymphocytes?f_ri=62112"},{"id":1212103,"name":"Antineoplastic Agents","url":"https://www.academia.edu/Documents/in/Antineoplastic_Agents?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_13905579 coauthored" data-work_id="13905579" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13905579/Percutaneous_left_atrial_appendage_closure_with_an_epicardial_suture_ligation_approach_A_prospective_randomized_pre_clinical_feasibility_study">Percutaneous left atrial appendage closure with an epicardial suture ligation approach: A prospective randomized pre-clinical feasibility study</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The aim of this study was to evaluate the results associated with left atrial appendage closure (LAAC) with the AMPLATZER Cardiac Plug (ACP) (St. Jude Medical, Minneapolis, Minnesota) in patients with nonvalvular atrial fibrillation and... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_13905579" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The aim of this study was to evaluate the results associated with left atrial appendage closure (LAAC) with the AMPLATZER Cardiac Plug (ACP) (St. Jude Medical, Minneapolis, Minnesota) in patients with nonvalvular atrial fibrillation and absolute contraindications to anticoagulation therapy.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13905579" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="ed10756ad2b7ba7d6c66840e190e45be" 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pancreatitis. Currently, guided fine needle aspiration is the only means for an early and accurate diagnosis of infected... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_13827208" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Background-Infection of pancreatic necrosis has a major impact on clinical course, management, and outcome in acute pancreatitis. Currently, guided fine needle aspiration is the only means for an early and accurate diagnosis of infected necrosis. Procalcitonin (PCT), a 116 amino acid propeptide of calcitonin, and interleukin 8 (IL-8), a strong neutrophil activating cytokine, are markers of severe inflammation and sepsis. Aims-To analyse the clinical value of PCT and IL-8 as biochemical parameters for predicting infected necrosis in acute pancreatitis. Patients and methods-Fifty patients with acute pancreatitis entered this prospective study and were stratified into three groups according to morphological and bacteriological findings: 18 patients with oedematous pancreatitis (group I), 14 patients with sterile necrosis (group II), and 18 patients who developed infected necrosis a median of 13.5 days after the onset of symptoms (group III). After admission serum samples were drawn daily for two weeks. Concentrations of PCT and IL-8 were measured by chemoluminescent immunoassays (upper reference range 0.5 ng/ml for PCT and 70 pg/ml for IL-8).</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13827208" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="f467fb0cbb0f2fc3bf5e2e6aac7b95df" rel="nofollow" data-download="{"attachment_id":44905671,"asset_id":13827208,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44905671/download_file?st=MTczOTgwMzc0NSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32922931" href="https://uniklinik-saarland.academia.edu/JensMayer">Jens Mayer</a><script data-card-contents-for-user="32922931" type="text/json">{"id":32922931,"first_name":"Jens","last_name":"Mayer","domain_name":"uniklinik-saarland","page_name":"JensMayer","display_name":"Jens Mayer","profile_url":"https://uniklinik-saarland.academia.edu/JensMayer?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_13827208 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="13827208"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 13827208, container: ".js-paper-rank-work_13827208", }); 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Currently, guided fine needle aspiration is the only means for an early and accurate diagnosis of infected necrosis. Procalcitonin (PCT), a 116 amino acid propeptide of calcitonin, and interleukin 8 (IL-8), a strong neutrophil activating cytokine, are markers of severe inflammation and sepsis. Aims-To analyse the clinical value of PCT and IL-8 as biochemical parameters for predicting infected necrosis in acute pancreatitis. Patients and methods-Fifty patients with acute pancreatitis entered this prospective study and were stratified into three groups according to morphological and bacteriological findings: 18 patients with oedematous pancreatitis (group I), 14 patients with sterile necrosis (group II), and 18 patients who developed infected necrosis a median of 13.5 days after the onset of symptoms (group III). After admission serum samples were drawn daily for two weeks. Concentrations of PCT and IL-8 were measured by chemoluminescent immunoassays (upper reference range 0.5 ng/ml for PCT and 70 pg/ml for IL-8).","downloadable_attachments":[{"id":44905671,"asset_id":13827208,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32922931,"first_name":"Jens","last_name":"Mayer","domain_name":"uniklinik-saarland","page_name":"JensMayer","display_name":"Jens Mayer","profile_url":"https://uniklinik-saarland.academia.edu/JensMayer?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":3243,"name":"Nonparametric Statistics","url":"https://www.academia.edu/Documents/in/Nonparametric_Statistics?f_ri=62112","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":70432,"name":"Course Management 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Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences?f_ri=62112"},{"id":3989031,"name":"Referral and consultation","url":"https://www.academia.edu/Documents/in/Referral_and_consultation?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_11061737" data-work_id="11061737" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/11061737/Communication_factors_in_the_follow_up_of_abnormal_mammograms">Communication factors in the follow-up of abnormal mammograms</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">To identify the communication factors that are significantly associated with appropriate short-term follow-up of abnormal mammograms.</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/11061737" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="bdc7db6ddf346ae0832ea901647b64ce" rel="nofollow" data-download="{"attachment_id":46930159,"asset_id":11061737,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46930159/download_file?st=MTczOTgwMzc0NSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa 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data-has-card-for-ri="859" rel="nofollow" href="https://www.academia.edu/Documents/in/Communication">Communication</a>, <script data-card-contents-for-ri="859" type="text/json">{"id":859,"name":"Communication","url":"https://www.academia.edu/Documents/in/Communication?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="2974" rel="nofollow" href="https://www.academia.edu/Documents/in/Primary_Health_Care">Primary Health Care</a>, <script data-card-contents-for-ri="2974" type="text/json">{"id":2974,"name":"Primary Health Care","url":"https://www.academia.edu/Documents/in/Primary_Health_Care?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="3286" rel="nofollow" href="https://www.academia.edu/Documents/in/Patient_Safety">Patient Safety</a>, <script data-card-contents-for-ri="3286" type="text/json">{"id":3286,"name":"Patient 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with appropriate short-term follow-up of abnormal mammograms.","downloadable_attachments":[{"id":46930159,"asset_id":11061737,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":26747059,"first_name":"Eric","last_name":"Poon","domain_name":"independent","page_name":"PoonE","display_name":"Eric Poon","profile_url":"https://independent.academia.edu/PoonE?f_ri=62112","photo":"https://0.academia-photos.com/26747059/27300208/25679644/s65_eric.poon.jpg"}],"research_interests":[{"id":859,"name":"Communication","url":"https://www.academia.edu/Documents/in/Communication?f_ri=62112","nofollow":true},{"id":2974,"name":"Primary Health Care","url":"https://www.academia.edu/Documents/in/Primary_Health_Care?f_ri=62112","nofollow":true},{"id":3286,"name":"Patient Safety","url":"https://www.academia.edu/Documents/in/Patient_Safety?f_ri=62112","nofollow":true},{"id":8974,"name":"Quality of Mental Health Care","url":"https://www.academia.edu/Documents/in/Quality_of_Mental_Health_Care?f_ri=62112","nofollow":true},{"id":10572,"name":"General Internal Medicine","url":"https://www.academia.edu/Documents/in/General_Internal_Medicine?f_ri=62112"},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112"},{"id":69426,"name":"General","url":"https://www.academia.edu/Documents/in/General?f_ri=62112"},{"id":209590,"name":"Mammography","url":"https://www.academia.edu/Documents/in/Mammography?f_ri=62112"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112"},{"id":414843,"name":"Longitudinal Study","url":"https://www.academia.edu/Documents/in/Longitudinal_Study?f_ri=62112"},{"id":874382,"name":"Medical Records","url":"https://www.academia.edu/Documents/in/Medical_Records?f_ri=62112"},{"id":1034177,"name":"Continuity of Patient Care","url":"https://www.academia.edu/Documents/in/Continuity_of_Patient_Care?f_ri=62112"},{"id":1587858,"name":"Confidence Interval","url":"https://www.academia.edu/Documents/in/Confidence_Interval?f_ri=62112"},{"id":2000388,"name":"Insurance Coverage","url":"https://www.academia.edu/Documents/in/Insurance_Coverage?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_3284221" data-work_id="3284221" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/3284221/Adherence_to_sport_injury_rehabilitation_programs_an_integrated_psycho_social_approach_Rehabilitation_adherence_in_sport">Adherence to sport injury rehabilitation programs: an integrated psycho-social approach: Rehabilitation adherence in sport</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The aim of the present study was to examine an adapted integrated psycho-social model to predict sport injury rehabilitation adherence. A longitudinal prospective design was used whereby 70 patients attending private physiotherapy clinics... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_3284221" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The aim of the present study was to examine an adapted integrated psycho-social model to predict sport injury rehabilitation adherence. A longitudinal prospective design was used whereby 70 patients attending private physiotherapy clinics completed a battery of questionnaires both pre- and post-rehabilitation treatment based on the adapted framework. All participants were receiving treatment for tendonitis-related injuries. Adherence was monitored prospectively over the entire rehabilitation program using an observational measure of clinic adherence, a self-report measure of home-based adherence, in addition to monitoring attendance at rehabilitation sessions. In the initial phase of rehabilitation learning goal orientation, attitudes and perceived severity were found to predict rehabilitation intention. Intentions were also found to mediate the relationship between the aforementioned variables and clinic rehabilitation. Self-efficacy and self-motivation were predictors of clinic rehabilitation and attendance but not home rehabilitation. During the maintenance phase of rehabilitation coping ability and social support were predictors regarding all three measures of adherence. Implications for practitioners rehabilitating injured athletes are discussed.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/3284221" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="57d9d73a1c27729164a7ca33cb1a727d" rel="nofollow" data-download="{"attachment_id":50364801,"asset_id":3284221,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/50364801/download_file?st=MTczOTgwMzc0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="1800946" href="https://qut.academia.edu/RemcoPolman">Remco Polman</a><script data-card-contents-for-user="1800946" type="text/json">{"id":1800946,"first_name":"Remco","last_name":"Polman","domain_name":"qut","page_name":"RemcoPolman","display_name":"Remco Polman","profile_url":"https://qut.academia.edu/RemcoPolman?f_ri=62112","photo":"https://0.academia-photos.com/1800946/1371720/12887544/s65_remco.polman.jpg"}</script></span></span></li><li class="js-paper-rank-work_3284221 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="3284221"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 3284221, container: ".js-paper-rank-work_3284221", }); 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A longitudinal prospective design was used whereby 70 patients attending private physiotherapy clinics completed a battery of questionnaires both pre- and post-rehabilitation treatment based on the adapted framework. All participants were receiving treatment for tendonitis-related injuries. Adherence was monitored prospectively over the entire rehabilitation program using an observational measure of clinic adherence, a self-report measure of home-based adherence, in addition to monitoring attendance at rehabilitation sessions. In the initial phase of rehabilitation learning goal orientation, attitudes and perceived severity were found to predict rehabilitation intention. Intentions were also found to mediate the relationship between the aforementioned variables and clinic rehabilitation. Self-efficacy and self-motivation were predictors of clinic rehabilitation and attendance but not home rehabilitation. During the maintenance phase of rehabilitation coping ability and social support were predictors regarding all three measures of adherence. Implications for practitioners rehabilitating injured athletes are discussed.","downloadable_attachments":[{"id":50364801,"asset_id":3284221,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":1800946,"first_name":"Remco","last_name":"Polman","domain_name":"qut","page_name":"RemcoPolman","display_name":"Remco Polman","profile_url":"https://qut.academia.edu/RemcoPolman?f_ri=62112","photo":"https://0.academia-photos.com/1800946/1371720/12887544/s65_remco.polman.jpg"}],"research_interests":[{"id":60,"name":"Mechanical Engineering","url":"https://www.academia.edu/Documents/in/Mechanical_Engineering?f_ri=62112","nofollow":true},{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=62112","nofollow":true},{"id":646,"name":"Sports Medicine","url":"https://www.academia.edu/Documents/in/Sports_Medicine?f_ri=62112","nofollow":true},{"id":44293,"name":"Literature Review","url":"https://www.academia.edu/Documents/in/Literature_Review?f_ri=62112","nofollow":true},{"id":46406,"name":"Motivation","url":"https://www.academia.edu/Documents/in/Motivation?f_ri=62112"},{"id":50456,"name":"Sports","url":"https://www.academia.edu/Documents/in/Sports?f_ri=62112"},{"id":50581,"name":"Self Efficacy","url":"https://www.academia.edu/Documents/in/Self_Efficacy?f_ri=62112"},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112"},{"id":123230,"name":"Regression Analysis","url":"https://www.academia.edu/Documents/in/Regression_Analysis?f_ri=62112"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=62112"},{"id":135005,"name":"Patient Compliance","url":"https://www.academia.edu/Documents/in/Patient_Compliance?f_ri=62112"},{"id":139358,"name":"Conceptual Model","url":"https://www.academia.edu/Documents/in/Conceptual_Model?f_ri=62112"},{"id":327850,"name":"Questionnaires","url":"https://www.academia.edu/Documents/in/Questionnaires?f_ri=62112"},{"id":330953,"name":"Longitudinal Studies","url":"https://www.academia.edu/Documents/in/Longitudinal_Studies?f_ri=62112"},{"id":343667,"name":"Theoretical Models","url":"https://www.academia.edu/Documents/in/Theoretical_Models?f_ri=62112"},{"id":412636,"name":"Theoretical Framework","url":"https://www.academia.edu/Documents/in/Theoretical_Framework?f_ri=62112"},{"id":419479,"name":"Applied Sport and Exercise Psychology","url":"https://www.academia.edu/Documents/in/Applied_Sport_and_Exercise_Psychology?f_ri=62112"},{"id":592611,"name":"Cognitive Appraisal","url":"https://www.academia.edu/Documents/in/Cognitive_Appraisal?f_ri=62112"},{"id":1274629,"name":"Area of Interest","url":"https://www.academia.edu/Documents/in/Area_of_Interest?f_ri=62112"},{"id":2529977,"name":"attitude to health","url":"https://www.academia.edu/Documents/in/attitude_to_health?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_30731046" data-work_id="30731046" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/30731046/Limited_effects_of_growth_hormone_replacement_in_patients_with_GH_deficiency_during_long_term_cure_of_acromegaly">Limited effects of growth hormone replacement in patients with GH deficiency during long-term cure of acromegaly</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The aim of this study was to assess the effects of replacement with recombinant human growth hormone (rhGH) in patients with GH deficiency (GHD) after treatment of acromegaly. Intervention study. Sixteen patients (8 men, age 56 years),... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_30731046" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The aim of this study was to assess the effects of replacement with recombinant human growth hormone (rhGH) in patients with GH deficiency (GHD) after treatment of acromegaly. Intervention study. Sixteen patients (8 men, age 56 years), treated for acromegaly by surgery and radiotherapy, with an insufficient GH response to insulininduced hypoglycaemia, were treated with 1 year of rhGH replacement. Study parameters were assessed at baseline and after 1 year of rhGH replacement. Study parameters were cardiac function, body composition, bone mineral density (BMD), fasting lipids, glucose, bone turnover markers, and Quality of Life (QoL). During rhGH replacement IGF-I concentrations increased from -0.4 ± 0.7 to 1.0 ± 1.5 SD (P = 0.001), with a mean daily dose of 0.2 ± 0.1 mg in men and 0.3 ± 0.2 mg in women. Nonetheless, rhGH replacement did not alter cardiac function, lipid and glucose concentrations, body composition or QoL. Bone turnover markers (PINP and b crosslaps) levels increased (P = 0.005 and P = 0.021, respectively), paralleled by a small, but significant decrease in BMD of the hip. The beneficial effects of rhGH replacement in patients with GHD during cure from acromegaly are limited in this study.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/30731046" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="d0d9e0ea2aae2dea5616a60793a98348" rel="nofollow" data-download="{"attachment_id":51178700,"asset_id":30731046,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/51178700/download_file?st=MTczOTgwMzc0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="58403059" href="https://independent.academia.edu/FerdinandRoelfsema">Ferdinand Roelfsema</a><script data-card-contents-for-user="58403059" type="text/json">{"id":58403059,"first_name":"Ferdinand","last_name":"Roelfsema","domain_name":"independent","page_name":"FerdinandRoelfsema","display_name":"Ferdinand Roelfsema","profile_url":"https://independent.academia.edu/FerdinandRoelfsema?f_ri=62112","photo":"https://0.academia-photos.com/58403059/49115808/37085760/s65_ferdinand.roelfsema.png"}</script></span></span></li><li class="js-paper-rank-work_30731046 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="30731046"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 30731046, container: ".js-paper-rank-work_30731046", }); 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$(".js-view-count[data-work-id=30731046]").text(description); $(".js-view-count-work_30731046").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_30731046").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="30731046"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">20</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="7470" rel="nofollow" href="https://www.academia.edu/Documents/in/Quality_of_life">Quality of life</a>, <script data-card-contents-for-ri="7470" type="text/json">{"id":7470,"name":"Quality of life","url":"https://www.academia.edu/Documents/in/Quality_of_life?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="12426" rel="nofollow" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a>, <script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="52562" rel="nofollow" href="https://www.academia.edu/Documents/in/Growth_Hormone">Growth Hormone</a>, <script data-card-contents-for-ri="52562" type="text/json">{"id":52562,"name":"Growth Hormone","url":"https://www.academia.edu/Documents/in/Growth_Hormone?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a><script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=30731046]'), work: {"id":30731046,"title":"Limited effects of growth hormone replacement in patients with GH deficiency during long-term cure of acromegaly","created_at":"2017-01-04T04:02:42.401-08:00","url":"https://www.academia.edu/30731046/Limited_effects_of_growth_hormone_replacement_in_patients_with_GH_deficiency_during_long_term_cure_of_acromegaly?f_ri=62112","dom_id":"work_30731046","summary":"The aim of this study was to assess the effects of replacement with recombinant human growth hormone (rhGH) in patients with GH deficiency (GHD) after treatment of acromegaly. Intervention study. Sixteen patients (8 men, age 56 years), treated for acromegaly by surgery and radiotherapy, with an insufficient GH response to insulininduced hypoglycaemia, were treated with 1 year of rhGH replacement. Study parameters were assessed at baseline and after 1 year of rhGH replacement. Study parameters were cardiac function, body composition, bone mineral density (BMD), fasting lipids, glucose, bone turnover markers, and Quality of Life (QoL). During rhGH replacement IGF-I concentrations increased from -0.4 ± 0.7 to 1.0 ± 1.5 SD (P = 0.001), with a mean daily dose of 0.2 ± 0.1 mg in men and 0.3 ± 0.2 mg in women. Nonetheless, rhGH replacement did not alter cardiac function, lipid and glucose concentrations, body composition or QoL. Bone turnover markers (PINP and b crosslaps) levels increased (P = 0.005 and P = 0.021, respectively), paralleled by a small, but significant decrease in BMD of the hip. The beneficial effects of rhGH replacement in patients with GHD during cure from acromegaly are limited in this study.","downloadable_attachments":[{"id":51178700,"asset_id":30731046,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":58403059,"first_name":"Ferdinand","last_name":"Roelfsema","domain_name":"independent","page_name":"FerdinandRoelfsema","display_name":"Ferdinand Roelfsema","profile_url":"https://independent.academia.edu/FerdinandRoelfsema?f_ri=62112","photo":"https://0.academia-photos.com/58403059/49115808/37085760/s65_ferdinand.roelfsema.png"}],"research_interests":[{"id":7470,"name":"Quality of life","url":"https://www.academia.edu/Documents/in/Quality_of_life?f_ri=62112","nofollow":true},{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=62112","nofollow":true},{"id":52562,"name":"Growth Hormone","url":"https://www.academia.edu/Documents/in/Growth_Hormone?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":69565,"name":"Human Growth Hormone","url":"https://www.academia.edu/Documents/in/Human_Growth_Hormone?f_ri=62112"},{"id":71289,"name":"Glucose","url":"https://www.academia.edu/Documents/in/Glucose?f_ri=62112"},{"id":100336,"name":"Body Composition","url":"https://www.academia.edu/Documents/in/Body_Composition?f_ri=62112"},{"id":131495,"name":"Heart","url":"https://www.academia.edu/Documents/in/Heart?f_ri=62112"},{"id":139532,"name":"Bone Density","url":"https://www.academia.edu/Documents/in/Bone_Density?f_ri=62112"},{"id":184609,"name":"Lipid metabolism","url":"https://www.academia.edu/Documents/in/Lipid_metabolism?f_ri=62112"},{"id":208591,"name":"Hypopituitarism","url":"https://www.academia.edu/Documents/in/Hypopituitarism?f_ri=62112"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=62112"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=62112"},{"id":438516,"name":"Bone Mineral Density","url":"https://www.academia.edu/Documents/in/Bone_Mineral_Density?f_ri=62112"},{"id":613467,"name":"Intervention study","url":"https://www.academia.edu/Documents/in/Intervention_study?f_ri=62112"},{"id":656285,"name":"Acromegaly","url":"https://www.academia.edu/Documents/in/Acromegaly?f_ri=62112"},{"id":963794,"name":"Pituitary","url":"https://www.academia.edu/Documents/in/Pituitary?f_ri=62112"},{"id":1432367,"name":"Recombinant Human Growth Hormone","url":"https://www.academia.edu/Documents/in/Recombinant_Human_Growth_Hormone?f_ri=62112"},{"id":1621167,"name":"Hormone Replacement Therapy","url":"https://www.academia.edu/Documents/in/Hormone_Replacement_Therapy?f_ri=62112"},{"id":2481953,"name":"Cardiac function","url":"https://www.academia.edu/Documents/in/Cardiac_function?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_16245514" data-work_id="16245514" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/16245514/Contrast_Enhanced_Ultrasound_CEUS_For_The_Evaluation_Of_Focal_Liver_Lesions_A_Prospective_Multicenter_Study_Of_Its_Usefulness_In_Clinical_Practice">Contrast-Enhanced Ultrasound (CEUS) For The Evaluation Of Focal Liver Lesions – A Prospective Multicenter Study Of Its Usefulness In Clinical Practice</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/16245514" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="f40b33573cffcccac1733c0eabe1a151" rel="nofollow" data-download="{"attachment_id":42616796,"asset_id":16245514,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42616796/download_file?st=MTczOTgwMzc0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="35337755" href="https://independent.academia.edu/GSmira">G. Smira</a><script data-card-contents-for-user="35337755" type="text/json">{"id":35337755,"first_name":"G.","last_name":"Smira","domain_name":"independent","page_name":"GSmira","display_name":"G. 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Information and feeling in control were consistently associated with positive psychological outcomes. (BIRTH 17:1, March 1990)</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/16514275" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="83d3a4a5e4238c2d5d25575f081a4647" rel="nofollow" data-download="{"attachment_id":42452267,"asset_id":16514275,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42452267/download_file?st=MTczOTgwMzc0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="35755702" href="https://independent.academia.edu/JosephineGreen">Josephine Green</a><script data-card-contents-for-user="35755702" type="text/json">{"id":35755702,"first_name":"Josephine","last_name":"Green","domain_name":"independent","page_name":"JosephineGreen","display_name":"Josephine Green","profile_url":"https://independent.academia.edu/JosephineGreen?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_16514275 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="16514275"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 16514275, container: ".js-paper-rank-work_16514275", }); 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Information and feeling in control were consistently associated with positive psychological outcomes. (BIRTH 17:1, March 1990)","downloadable_attachments":[{"id":42452267,"asset_id":16514275,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":35755702,"first_name":"Josephine","last_name":"Green","domain_name":"independent","page_name":"JosephineGreen","display_name":"Josephine Green","profile_url":"https://independent.academia.edu/JosephineGreen?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112","nofollow":true},{"id":30494,"name":"England","url":"https://www.academia.edu/Documents/in/England?f_ri=62112","nofollow":true},{"id":49296,"name":"Birth","url":"https://www.academia.edu/Documents/in/Birth?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":62550,"name":"Pregnancy","url":"https://www.academia.edu/Documents/in/Pregnancy?f_ri=62112"},{"id":100383,"name":"Stereotyping","url":"https://www.academia.edu/Documents/in/Stereotyping?f_ri=62112"},{"id":327850,"name":"Questionnaires","url":"https://www.academia.edu/Documents/in/Questionnaires?f_ri=62112"},{"id":767909,"name":"Parity","url":"https://www.academia.edu/Documents/in/Parity?f_ri=62112"},{"id":1157423,"name":"Personal Satisfaction","url":"https://www.academia.edu/Documents/in/Personal_Satisfaction?f_ri=62112"},{"id":1312754,"name":"Prospective Study","url":"https://www.academia.edu/Documents/in/Prospective_Study?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_27449224 coauthored" data-work_id="27449224" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/27449224/Leaflet_area_as_a_determinant_of_tricuspid_regurgitation_severity_in_patients_with_pulmonary_hypertension">Leaflet area as a determinant of tricuspid regurgitation severity in patients with pulmonary hypertension</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Tricuspid regurgitation (TR) is a risk factor for mortality in pulmonary hypertension (PH). TR severity varies among patients with comparable degrees of PH and right ventricular remodeling. The contribution of leaflet adaptation to the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_27449224" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Tricuspid regurgitation (TR) is a risk factor for mortality in pulmonary hypertension (PH). TR severity varies among patients with comparable degrees of PH and right ventricular remodeling. The contribution of leaflet adaptation to the pathophysiology of TR has yet to be examined. We hypothesized that tricuspid leaflet area (TLA) is increased in PH, and that the adequacy of this increase relative to right ventricular remodeling determines TR severity. A prospective cohort of 255 patients with PH from pre and postcapillary pathogeneses was assembled from 2 centers. Patients underwent a 3-dimensional echocardiogram focused on the tricuspid apparatus. TLA was measured with the Omni 4D software package. Compared with normal controls, patients with PH had a 2-fold increase in right ventricular volumes, 62% increase in annular area, and 49% increase in TLA. Those with severe TR demonstrated inadequate increase in TLA relative to the closure area, such that the ratio of TLA:closure area &l...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/27449224" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="4bd7ac12089a3272d4729b3505c6353c" rel="nofollow" data-download="{"attachment_id":47707492,"asset_id":27449224,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/47707492/download_file?st=MTczOTgwMzc0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="51586568" href="https://independent.academia.edu/LanqiHua">Lanqi Hua</a><script data-card-contents-for-user="51586568" type="text/json">{"id":51586568,"first_name":"Lanqi","last_name":"Hua","domain_name":"independent","page_name":"LanqiHua","display_name":"Lanqi Hua","profile_url":"https://independent.academia.edu/LanqiHua?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-27449224">+1</span><div class="hidden js-additional-users-27449224"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/MarkHandschumacher">Mark Handschumacher</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-27449224'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-27449224').html(); 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TR severity varies among patients with comparable degrees of PH and right ventricular remodeling. The contribution of leaflet adaptation to the pathophysiology of TR has yet to be examined. We hypothesized that tricuspid leaflet area (TLA) is increased in PH, and that the adequacy of this increase relative to right ventricular remodeling determines TR severity. A prospective cohort of 255 patients with PH from pre and postcapillary pathogeneses was assembled from 2 centers. Patients underwent a 3-dimensional echocardiogram focused on the tricuspid apparatus. TLA was measured with the Omni 4D software package. Compared with normal controls, patients with PH had a 2-fold increase in right ventricular volumes, 62% increase in annular area, and 49% increase in TLA. Those with severe TR demonstrated inadequate increase in TLA relative to the closure area, such that the ratio of TLA:closure area \u0026l...","downloadable_attachments":[{"id":47707492,"asset_id":27449224,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":51586568,"first_name":"Lanqi","last_name":"Hua","domain_name":"independent","page_name":"LanqiHua","display_name":"Lanqi Hua","profile_url":"https://independent.academia.edu/LanqiHua?f_ri=62112","photo":"/images/s65_no_pic.png"},{"id":51666062,"first_name":"Mark","last_name":"Handschumacher","domain_name":"independent","page_name":"MarkHandschumacher","display_name":"Mark Handschumacher","profile_url":"https://independent.academia.edu/MarkHandschumacher?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":31958,"name":"Pulmonary Hypertension","url":"https://www.academia.edu/Documents/in/Pulmonary_Hypertension?f_ri=62112","nofollow":true},{"id":53293,"name":"Software","url":"https://www.academia.edu/Documents/in/Software?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=62112","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=62112"},{"id":803294,"name":"Ventricular Remodeling","url":"https://www.academia.edu/Documents/in/Ventricular_Remodeling?f_ri=62112"},{"id":1819399,"name":"Case Control Studies","url":"https://www.academia.edu/Documents/in/Case_Control_Studies?f_ri=62112"},{"id":2463800,"name":"Severity of Illness Index","url":"https://www.academia.edu/Documents/in/Severity_of_Illness_Index?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_14370365" data-work_id="14370365" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/14370365/Reimplantation_of_the_right_internal_thoracic_artery_as_a_free_graft_into_the_left_in_situ_internal_thoracic_artery_Y_Procedure_One_year_angiographic_results">Reimplantation of the right internal thoracic artery as a free graft into the left in situ internal thoracic artery (Y Procedure): One-year angiographic results</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Reimplantation of the right internal thoracic artery, as a free graft, into the left in situ internal thoracic artery (Y procedure) has enabled us to bypass more distant marginal vessels, which was not possible by the bilateral technique... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_14370365" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Reimplantation of the right internal thoracic artery, as a free graft, into the left in situ internal thoracic artery (Y procedure) has enabled us to bypass more distant marginal vessels, which was not possible by the bilateral technique alone. This prospective study was aimed at evaluating the clinical state of the patients and the degree of patency of grafts within 16 months of follow-up. All 80 patients who underwent the Y procedure between January 1988 and January 1992 were included. This group represented 10% of the 840 patients having coronary bypass during the same period. A total of 202 coronary anastomoses were performed in this series. Early postoperative (30 days) complications included three deaths (3.75%), eight myocardial infarctions (10%), one case of phrenic nerve paralysis (1.25%), two cases of respiratory failure (2.5%), and six wound infections (7.5%). At 3 months' follow-up, 96% of patients were free of symptoms. During the follow-up period, four patients died of noncardiac causes (lung, pancreatic, and brain cancer and rupture of an abdominal aortic aneurysm). At 1 year, 71 patients were free of symptoms (97%). Sixty-one patients underwent coronary angiography between 12 and 24 months. Six patients with peripheral arterial disease were not suitable for coronary angiography, and six refused to be tested. These 12 patients had normal thallium test results in the bypassed area (stress or dipyridamole test). The patency rate of the left internal thoracic artery was 98.3% (n = 60), occlusion rate 1.6% (n = 1), and incidence of threadlike arteries 4.9% (n = 3). Thus the rate of perfect patency was 93.4%. The patency rate of the right internal thoracic artery as a free graft was 93.4% (n = 57), occlusion rate 6.5% (n = 4), and the incidence of threadlike arteries 8% (n = 5). Thus the rate of perfect patency was 85.2%. A total of 169 anastomoses were studied. The rate of patency of the anastomoses to the left anterior descending coronary artery was 96% (n = 58) and the occlusion rate, 4% (n = 2). The patency rate of sequential anastomoses (side to side) to diagonal arteries was 100% (n = 16). Patency rate of anastomoses to obtuse marginal arteries was 95% (n = 58) and the rate of occlusion, 4.9% (n = 3). The patency rate of anastomoses to the posterior descending artery or distal branches of the right coronary artery was 80% (n = 4/5). We conclude that the Y procedure is a ~safe technique with an acceptable morbidity and a good patency rate. This procedure can be used when the in situ technique is not possible because of far-reaching distal marginal coronary arteries. (J THORAC CARDIOVASC SURG 1995;109:1042-8)</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/14370365" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="bf69efe653f2da8e5576d1c0aa121a64" rel="nofollow" data-download="{"attachment_id":44275349,"asset_id":14370365,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44275349/download_file?st=MTczOTgwMzc0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33313310" href="https://univ-brest.academia.edu/JacquesMansourati">Jacques Mansourati</a><script data-card-contents-for-user="33313310" type="text/json">{"id":33313310,"first_name":"Jacques","last_name":"Mansourati","domain_name":"univ-brest","page_name":"JacquesMansourati","display_name":"Jacques Mansourati","profile_url":"https://univ-brest.academia.edu/JacquesMansourati?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_14370365 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="14370365"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 14370365, container: ".js-paper-rank-work_14370365", }); 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$(".js-view-count[data-work-id=14370365]").text(description); $(".js-view-count-work_14370365").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_14370365").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="14370365"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">15</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a>, <script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="137516" rel="nofollow" href="https://www.academia.edu/Documents/in/Follow-up_studies">Follow-up studies</a>, <script data-card-contents-for-ri="137516" type="text/json">{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="167876" rel="nofollow" href="https://www.academia.edu/Documents/in/Myocardial_Revascularization">Myocardial Revascularization</a>, <script data-card-contents-for-ri="167876" type="text/json">{"id":167876,"name":"Myocardial Revascularization","url":"https://www.academia.edu/Documents/in/Myocardial_Revascularization?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="222776" rel="nofollow" href="https://www.academia.edu/Documents/in/Respiratory_Failure">Respiratory Failure</a><script data-card-contents-for-ri="222776" type="text/json">{"id":222776,"name":"Respiratory Failure","url":"https://www.academia.edu/Documents/in/Respiratory_Failure?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=14370365]'), work: {"id":14370365,"title":"Reimplantation of the right internal thoracic artery as a free graft into the left in situ internal thoracic artery (Y Procedure): One-year angiographic results","created_at":"2015-07-24T11:11:17.108-07:00","url":"https://www.academia.edu/14370365/Reimplantation_of_the_right_internal_thoracic_artery_as_a_free_graft_into_the_left_in_situ_internal_thoracic_artery_Y_Procedure_One_year_angiographic_results?f_ri=62112","dom_id":"work_14370365","summary":"Reimplantation of the right internal thoracic artery, as a free graft, into the left in situ internal thoracic artery (Y procedure) has enabled us to bypass more distant marginal vessels, which was not possible by the bilateral technique alone. This prospective study was aimed at evaluating the clinical state of the patients and the degree of patency of grafts within 16 months of follow-up. All 80 patients who underwent the Y procedure between January 1988 and January 1992 were included. This group represented 10% of the 840 patients having coronary bypass during the same period. A total of 202 coronary anastomoses were performed in this series. Early postoperative (30 days) complications included three deaths (3.75%), eight myocardial infarctions (10%), one case of phrenic nerve paralysis (1.25%), two cases of respiratory failure (2.5%), and six wound infections (7.5%). At 3 months' follow-up, 96% of patients were free of symptoms. During the follow-up period, four patients died of noncardiac causes (lung, pancreatic, and brain cancer and rupture of an abdominal aortic aneurysm). At 1 year, 71 patients were free of symptoms (97%). Sixty-one patients underwent coronary angiography between 12 and 24 months. Six patients with peripheral arterial disease were not suitable for coronary angiography, and six refused to be tested. These 12 patients had normal thallium test results in the bypassed area (stress or dipyridamole test). The patency rate of the left internal thoracic artery was 98.3% (n = 60), occlusion rate 1.6% (n = 1), and incidence of threadlike arteries 4.9% (n = 3). Thus the rate of perfect patency was 93.4%. The patency rate of the right internal thoracic artery as a free graft was 93.4% (n = 57), occlusion rate 6.5% (n = 4), and the incidence of threadlike arteries 8% (n = 5). Thus the rate of perfect patency was 85.2%. A total of 169 anastomoses were studied. The rate of patency of the anastomoses to the left anterior descending coronary artery was 96% (n = 58) and the occlusion rate, 4% (n = 2). The patency rate of sequential anastomoses (side to side) to diagonal arteries was 100% (n = 16). Patency rate of anastomoses to obtuse marginal arteries was 95% (n = 58) and the rate of occlusion, 4.9% (n = 3). The patency rate of anastomoses to the posterior descending artery or distal branches of the right coronary artery was 80% (n = 4/5). We conclude that the Y procedure is a ~safe technique with an acceptable morbidity and a good patency rate. This procedure can be used when the in situ technique is not possible because of far-reaching distal marginal coronary arteries. (J THORAC CARDIOVASC SURG 1995;109:1042-8)","downloadable_attachments":[{"id":44275349,"asset_id":14370365,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33313310,"first_name":"Jacques","last_name":"Mansourati","domain_name":"univ-brest","page_name":"JacquesMansourati","display_name":"Jacques Mansourati","profile_url":"https://univ-brest.academia.edu/JacquesMansourati?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies?f_ri=62112","nofollow":true},{"id":167876,"name":"Myocardial Revascularization","url":"https://www.academia.edu/Documents/in/Myocardial_Revascularization?f_ri=62112","nofollow":true},{"id":222776,"name":"Respiratory Failure","url":"https://www.academia.edu/Documents/in/Respiratory_Failure?f_ri=62112","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112"},{"id":291048,"name":"Cardiac Catheterization","url":"https://www.academia.edu/Documents/in/Cardiac_Catheterization?f_ri=62112"},{"id":374984,"name":"Coronary Angiography","url":"https://www.academia.edu/Documents/in/Coronary_Angiography?f_ri=62112"},{"id":398808,"name":"Coronary heart disease","url":"https://www.academia.edu/Documents/in/Coronary_heart_disease?f_ri=62112"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=62112"},{"id":789977,"name":"Coronary Artery Disease","url":"https://www.academia.edu/Documents/in/Coronary_Artery_Disease?f_ri=62112"},{"id":1305425,"name":"Abdominal Aortic Aneurysm","url":"https://www.academia.edu/Documents/in/Abdominal_Aortic_Aneurysm?f_ri=62112"},{"id":1312754,"name":"Prospective Study","url":"https://www.academia.edu/Documents/in/Prospective_Study?f_ri=62112"},{"id":1831343,"name":"Peripheral artery disease","url":"https://www.academia.edu/Documents/in/Peripheral_artery_disease?f_ri=62112"},{"id":1883354,"name":"Thoracic and cardiovascular surgery","url":"https://www.academia.edu/Documents/in/Thoracic_and_cardiovascular_surgery?f_ri=62112"},{"id":2356404,"name":"Coronary artery","url":"https://www.academia.edu/Documents/in/Coronary_artery?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_10497290" data-work_id="10497290" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/10497290/Voriconazole_versus_natamycin_as_primary_treatment_in_fungal_corneal_ulcers">Voriconazole versus natamycin as primary treatment in fungal corneal ulcers</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">Background: To evaluate the efficacy of topical 1% voriconazole versus 5% natamycin in treatment of fungal corneal ulcers.</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/10497290" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="73d264d99a5dc836774d21de449a0273" rel="nofollow" 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type="text/json">{"id":25743033,"first_name":"Ravinder","last_name":"Kaur","domain_name":"independent","page_name":"RavinderKaur28","display_name":"Ravinder Kaur","profile_url":"https://independent.academia.edu/RavinderKaur28?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_10497290 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="10497290"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 10497290, container: ".js-paper-rank-work_10497290", }); });</script></li><li class="js-percentile-work_10497290 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 10497290; 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Solutions","url":"https://www.academia.edu/Documents/in/Ophthalmic_Solutions?f_ri=62112"},{"id":2178525,"name":"Indian Journal of Clinical and Experimental Ophthalmology","url":"https://www.academia.edu/Documents/in/Indian_Journal_of_Clinical_and_Experimental_Ophthalmology?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_17765349 coauthored" data-work_id="17765349" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/17765349/A_prospective_multicenter_derivation_of_a_biomarker_panel_to_assess_risk_of_organ_dysfunction_shock_and_death_in_emergency_department_patients_with_suspected_sepsis">A prospective, multicenter derivation of a biomarker panel to assess risk of organ dysfunction, shock, and death in emergency department patients with suspected sepsis</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">Objective: To define a biomarker panel to predict organ dysfunction, shock, and in-hospital mortality in emergency department (ED) patients with suspected sepsis.</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/17765349" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="cdde94ffaf12c1b8a7d85939bd43a8c1" rel="nofollow" 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itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/RonnyOtero">Ronny Otero</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-17765349'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-17765349').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_17765349 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="17765349"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 17765349, container: ".js-paper-rank-work_17765349", }); });</script></li><li class="js-percentile-work_17765349 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: 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Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=17765349]'), work: {"id":17765349,"title":"A prospective, multicenter derivation of a biomarker panel to assess risk of organ dysfunction, shock, and death in emergency department patients with suspected sepsis","created_at":"2015-11-04T14:58:18.656-08:00","url":"https://www.academia.edu/17765349/A_prospective_multicenter_derivation_of_a_biomarker_panel_to_assess_risk_of_organ_dysfunction_shock_and_death_in_emergency_department_patients_with_suspected_sepsis?f_ri=62112","dom_id":"work_17765349","summary":"Objective: To define a biomarker panel to predict organ dysfunction, shock, and in-hospital mortality in emergency department (ED) patients with suspected sepsis.","downloadable_attachments":[{"id":39697225,"asset_id":17765349,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":37670283,"first_name":"David","last_name":"Milzman","domain_name":"georgetown","page_name":"DavidMilzman","display_name":"David Milzman","profile_url":"https://georgetown.academia.edu/DavidMilzman?f_ri=62112","photo":"https://0.academia-photos.com/37670283/10610079/11843023/s65_david.milzman.jpg"},{"id":38739872,"first_name":"Judd","last_name":"Hollander","domain_name":"independent","page_name":"JuddHollander","display_name":"Judd Hollander","profile_url":"https://independent.academia.edu/JuddHollander?f_ri=62112","photo":"/images/s65_no_pic.png"},{"id":37786643,"first_name":"Tiffany","last_name":"Osborn","domain_name":"independent","page_name":"OsbornTiffany","display_name":"Tiffany 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studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112"},{"id":125076,"name":"Sepsis","url":"https://www.academia.edu/Documents/in/Sepsis?f_ri=62112"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=62112"},{"id":568482,"name":"Biological markers","url":"https://www.academia.edu/Documents/in/Biological_markers?f_ri=62112"},{"id":622589,"name":"Risk Assessment","url":"https://www.academia.edu/Documents/in/Risk_Assessment-2?f_ri=62112"},{"id":709138,"name":"Acute Phase Proteins","url":"https://www.academia.edu/Documents/in/Acute_Phase_Proteins?f_ri=62112"},{"id":901284,"name":"Hospital Mortality","url":"https://www.academia.edu/Documents/in/Hospital_Mortality?f_ri=62112"},{"id":1271254,"name":"Multiple Organ Failure","url":"https://www.academia.edu/Documents/in/Multiple_Organ_Failure?f_ri=62112"},{"id":1318932,"name":"Predictive value of tests","url":"https://www.academia.edu/Documents/in/Predictive_value_of_tests?f_ri=62112"},{"id":1435137,"name":"Emergency Department","url":"https://www.academia.edu/Documents/in/Emergency_Department?f_ri=62112"},{"id":1924712,"name":"Interleukin","url":"https://www.academia.edu/Documents/in/Interleukin?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_29122947" data-work_id="29122947" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/29122947/Maternal_role_development_following_childbirth_among_Australian_women">Maternal role development following childbirth among Australian women</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">This paper is a report on the examination of demographic, birthing and social correlates of maternal role development in childbearing women.</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/29122947" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="829d60dc7851a6bab4a267ceaa07b531" rel="nofollow" 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window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_29122947"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_29122947 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="29122947"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29122947; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29122947]").text(description); $(".js-view-count-work_29122947").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_29122947").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="29122947"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">12</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="588" rel="nofollow" href="https://www.academia.edu/Documents/in/Nursing">Nursing</a>, <script data-card-contents-for-ri="588" type="text/json">{"id":588,"name":"Nursing","url":"https://www.academia.edu/Documents/in/Nursing?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4545" rel="nofollow" href="https://www.academia.edu/Documents/in/Parenting">Parenting</a>, <script data-card-contents-for-ri="4545" type="text/json">{"id":4545,"name":"Parenting","url":"https://www.academia.edu/Documents/in/Parenting?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="11015" rel="nofollow" href="https://www.academia.edu/Documents/in/Social_Support">Social Support</a>, <script data-card-contents-for-ri="11015" type="text/json">{"id":11015,"name":"Social Support","url":"https://www.academia.edu/Documents/in/Social_Support?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a><script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=29122947]'), work: {"id":29122947,"title":"Maternal role development following childbirth among Australian women","created_at":"2016-10-13T05:16:05.661-07:00","url":"https://www.academia.edu/29122947/Maternal_role_development_following_childbirth_among_Australian_women?f_ri=62112","dom_id":"work_29122947","summary":"This paper is a report on the examination of demographic, birthing and social correlates of maternal role development in childbearing women.","downloadable_attachments":[{"id":49569459,"asset_id":29122947,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":54954763,"first_name":"Winsome St","last_name":"John","domain_name":"independent","page_name":"WinsomeStJohn","display_name":"Winsome St John","profile_url":"https://independent.academia.edu/WinsomeStJohn?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":588,"name":"Nursing","url":"https://www.academia.edu/Documents/in/Nursing?f_ri=62112","nofollow":true},{"id":4545,"name":"Parenting","url":"https://www.academia.edu/Documents/in/Parenting?f_ri=62112","nofollow":true},{"id":11015,"name":"Social Support","url":"https://www.academia.edu/Documents/in/Social_Support?f_ri=62112","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112","nofollow":true},{"id":57912,"name":"Marriage","url":"https://www.academia.edu/Documents/in/Marriage?f_ri=62112"},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112"},{"id":65970,"name":"Advanced Nursing Practice","url":"https://www.academia.edu/Documents/in/Advanced_Nursing_Practice?f_ri=62112"},{"id":68567,"name":"Queensland","url":"https://www.academia.edu/Documents/in/Queensland?f_ri=62112"},{"id":211917,"name":"Length of Stay","url":"https://www.academia.edu/Documents/in/Length_of_Stay?f_ri=62112"},{"id":535184,"name":"Maternal Behavior","url":"https://www.academia.edu/Documents/in/Maternal_Behavior?f_ri=62112"},{"id":546419,"name":"Age Factors","url":"https://www.academia.edu/Documents/in/Age_Factors?f_ri=62112"},{"id":767173,"name":"Parturition","url":"https://www.academia.edu/Documents/in/Parturition?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_68552961" data-work_id="68552961" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/68552961/Auditory_brainstem_response_in_premature_and_full_term_children">Auditory brainstem response in premature and full-term children</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objectives: To compare the absolute latencies of peaks I, III and V and interpeak intervals of premature and full-term children. Methods: Prospective, comparative cohort study. Study subjects were premature and full-term children with... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_68552961" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objectives: To compare the absolute latencies of peaks I, III and V and interpeak intervals of premature and full-term children. Methods: Prospective, comparative cohort study. Study subjects were premature and full-term children with auditory brainstem response (ABR) measured at ages 4, 12 and 20 months. The children had previously undergone otorhinolaryngolic and audiologic evaluations to exclude those with altered hearing. Results: One hundred and twenty-four children were included in the study (73 premature). No differences were found between children of different sexes nor between the right and left ears of the individual children, so the statistical unit sed for the study was the ear. Using the t-test for independent samples, the absolute latencies of peaks I, III and IV and the interpeak intervals I-III, I-IV and III-V presented statistically significant differences between the groups at ages 4 and 12 months. At 20 months, only peak I failed to show a difference in absolute latency. Strong inverse correlation was found (Pearson's coefficient) between gestational age and absolute peak latency, as well as for interpeak intervals. Conclusions: Maturation of the auditory system, as measured by ABR, occurs differently between premature and full-term children, suggesting that gestational age be taken into consideration when using ABR in premature children younger than 20 months old.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/68552961" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="eea0b5038cc938d8987b1c32f8a2a05b" rel="nofollow" data-download="{"attachment_id":78988466,"asset_id":68552961,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/78988466/download_file?st=MTczOTgwMzc0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="52454091" href="https://32.academia.edu/PedroCoser">Pedro Coser</a><script data-card-contents-for-user="52454091" type="text/json">{"id":52454091,"first_name":"Pedro","last_name":"Coser","domain_name":"32","page_name":"PedroCoser","display_name":"Pedro Coser","profile_url":"https://32.academia.edu/PedroCoser?f_ri=62112","photo":"https://0.academia-photos.com/52454091/14530806/31945312/s65_pedro.coser.jpg"}</script></span></span></li><li class="js-paper-rank-work_68552961 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="68552961"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 68552961, container: ".js-paper-rank-work_68552961", }); });</script></li><li class="js-percentile-work_68552961 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 68552961; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_68552961"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_68552961 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="68552961"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 68552961; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=68552961]").text(description); $(".js-view-count-work_68552961").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_68552961").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="68552961"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">13</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a>, <script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="64933" rel="nofollow" href="https://www.academia.edu/Documents/in/Child">Child</a>, <script data-card-contents-for-ri="64933" type="text/json">{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="76880" rel="nofollow" href="https://www.academia.edu/Documents/in/Hearing_disorders">Hearing disorders</a><script data-card-contents-for-ri="76880" type="text/json">{"id":76880,"name":"Hearing disorders","url":"https://www.academia.edu/Documents/in/Hearing_disorders?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=68552961]'), work: {"id":68552961,"title":"Auditory brainstem response in premature and full-term children","created_at":"2022-01-17T11:54:25.044-08:00","url":"https://www.academia.edu/68552961/Auditory_brainstem_response_in_premature_and_full_term_children?f_ri=62112","dom_id":"work_68552961","summary":"Objectives: To compare the absolute latencies of peaks I, III and V and interpeak intervals of premature and full-term children. Methods: Prospective, comparative cohort study. Study subjects were premature and full-term children with auditory brainstem response (ABR) measured at ages 4, 12 and 20 months. The children had previously undergone otorhinolaryngolic and audiologic evaluations to exclude those with altered hearing. Results: One hundred and twenty-four children were included in the study (73 premature). No differences were found between children of different sexes nor between the right and left ears of the individual children, so the statistical unit sed for the study was the ear. Using the t-test for independent samples, the absolute latencies of peaks I, III and IV and the interpeak intervals I-III, I-IV and III-V presented statistically significant differences between the groups at ages 4 and 12 months. At 20 months, only peak I failed to show a difference in absolute latency. Strong inverse correlation was found (Pearson's coefficient) between gestational age and absolute peak latency, as well as for interpeak intervals. Conclusions: Maturation of the auditory system, as measured by ABR, occurs differently between premature and full-term children, suggesting that gestational age be taken into consideration when using ABR in premature children younger than 20 months old.","downloadable_attachments":[{"id":78988466,"asset_id":68552961,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":52454091,"first_name":"Pedro","last_name":"Coser","domain_name":"32","page_name":"PedroCoser","display_name":"Pedro Coser","profile_url":"https://32.academia.edu/PedroCoser?f_ri=62112","photo":"https://0.academia-photos.com/52454091/14530806/31945312/s65_pedro.coser.jpg"}],"research_interests":[{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=62112","nofollow":true},{"id":76880,"name":"Hearing disorders","url":"https://www.academia.edu/Documents/in/Hearing_disorders?f_ri=62112","nofollow":true},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=62112"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112"},{"id":253560,"name":"Newborn Infant","url":"https://www.academia.edu/Documents/in/Newborn_Infant?f_ri=62112"},{"id":766434,"name":"Auditory Brainstem Response","url":"https://www.academia.edu/Documents/in/Auditory_Brainstem_Response?f_ri=62112"},{"id":797418,"name":"Gestational Age","url":"https://www.academia.edu/Documents/in/Gestational_Age?f_ri=62112"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=62112"},{"id":2489700,"name":"Child preschool","url":"https://www.academia.edu/Documents/in/Child_preschool?f_ri=62112"},{"id":3693190,"name":"mass Screening","url":"https://www.academia.edu/Documents/in/mass_Screening?f_ri=62112"},{"id":3789883,"name":"Paediatrics and reproductive medicine","url":"https://www.academia.edu/Documents/in/Paediatrics_and_reproductive_medicine?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_49058360" data-work_id="49058360" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/49058360/SCENARIOS_LEARNING_AND_ACTING_FROM_THE_FUTURE_PART_3_THREE_SCHOOLS_OF_SCENARIO_PLANNING">SCENARIOS: LEARNING AND ACTING FROM THE FUTURE PART 3: THREE SCHOOLS OF SCENARIO PLANNING</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">In 1987 William Huss and Edward Honton published the paper “Scenario Planning—What style should you use?”, in which they distinguish three types of scenario development approaches, namely ‘Intuitive Logics’, ‘Trend-Impact Analysis’ and... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_49058360" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">In 1987 William Huss and Edward Honton published the paper “Scenario Planning—What style should you use?”, in which they distinguish three types of scenario development approaches, namely ‘Intuitive Logics’, ‘Trend-Impact Analysis’ and ‘Cross-Impact Analysis’.<br />In 2002, Heijden, Bradfield, Burt, and Wright (Heijden et al., 2002: 128-129; Bradfield, et al.: 805) stated that the categorization presented above had two problems: the first one relates to the omission of the “La Prospective” methodology which it is for these authors a true school of Scenario Planning; the second one relates to the fact that the “Trend Impact Analysis” and the “Cross Impact Analysis”, although being standalone techniques, share the same foundations, which are anchored in the mathematical improvement of extrapolated time series data. In this sense, these two techniques must be viewed as a coherent group of techniques which, for convenience, those authors called `probabilistic modified trends' (PMT) methodology (Heijden, et al., 2002).<br />In this article we will present and characterize the three major schools or techniques of Scenario Planning identified by Bradfield et al. (20052): “Intuitive Logics”, the “Probabilistic Modified Trends” and the “La Prospective” methodologies.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/49058360" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="99145d31a23e133c789e5bf4c2ee726c" rel="nofollow" data-download="{"attachment_id":67448908,"asset_id":49058360,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/67448908/download_file?st=MTczOTgwMzc0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="131109111" href="https://ulisboa.academia.edu/PauloSoeiroCarvalho">Paulo Soeiro Carvalho</a><script data-card-contents-for-user="131109111" type="text/json">{"id":131109111,"first_name":"Paulo","last_name":"Soeiro Carvalho","domain_name":"ulisboa","page_name":"PauloSoeiroCarvalho","display_name":"Paulo Soeiro Carvalho","profile_url":"https://ulisboa.academia.edu/PauloSoeiroCarvalho?f_ri=62112","photo":"https://0.academia-photos.com/131109111/52125183/40224263/s65_paulo.soeiro_carvalho.jpg"}</script></span></span></li><li class="js-paper-rank-work_49058360 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="49058360"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 49058360, container: ".js-paper-rank-work_49058360", }); });</script></li><li class="js-percentile-work_49058360 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 49058360; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_49058360"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_49058360 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="49058360"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 49058360; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=49058360]").text(description); $(".js-view-count-work_49058360").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_49058360").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="49058360"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="3477" rel="nofollow" href="https://www.academia.edu/Documents/in/Strategic_Foresight">Strategic Foresight</a>, <script data-card-contents-for-ri="3477" type="text/json">{"id":3477,"name":"Strategic Foresight","url":"https://www.academia.edu/Documents/in/Strategic_Foresight?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="5009" rel="nofollow" href="https://www.academia.edu/Documents/in/Strategic_Management">Strategic Management</a>, <script data-card-contents-for-ri="5009" type="text/json">{"id":5009,"name":"Strategic Management","url":"https://www.academia.edu/Documents/in/Strategic_Management?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="17581" rel="nofollow" href="https://www.academia.edu/Documents/in/Futures_Studies">Futures Studies</a>, <script data-card-contents-for-ri="17581" type="text/json">{"id":17581,"name":"Futures Studies","url":"https://www.academia.edu/Documents/in/Futures_Studies?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="18289" rel="nofollow" href="https://www.academia.edu/Documents/in/Scenario_planning">Scenario planning</a><script data-card-contents-for-ri="18289" type="text/json">{"id":18289,"name":"Scenario planning","url":"https://www.academia.edu/Documents/in/Scenario_planning?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=49058360]'), work: {"id":49058360,"title":"SCENARIOS: LEARNING AND ACTING FROM THE FUTURE PART 3: THREE SCHOOLS OF SCENARIO PLANNING","created_at":"2021-05-28T01:30:26.003-07:00","url":"https://www.academia.edu/49058360/SCENARIOS_LEARNING_AND_ACTING_FROM_THE_FUTURE_PART_3_THREE_SCHOOLS_OF_SCENARIO_PLANNING?f_ri=62112","dom_id":"work_49058360","summary":"In 1987 William Huss and Edward Honton published the paper “Scenario Planning—What style should you use?”, in which they distinguish three types of scenario development approaches, namely ‘Intuitive Logics’, ‘Trend-Impact Analysis’ and ‘Cross-Impact Analysis’.\nIn 2002, Heijden, Bradfield, Burt, and Wright (Heijden et al., 2002: 128-129; Bradfield, et al.: 805) stated that the categorization presented above had two problems: the first one relates to the omission of the “La Prospective” methodology which it is for these authors a true school of Scenario Planning; the second one relates to the fact that the “Trend Impact Analysis” and the “Cross Impact Analysis”, although being standalone techniques, share the same foundations, which are anchored in the mathematical improvement of extrapolated time series data. In this sense, these two techniques must be viewed as a coherent group of techniques which, for convenience, those authors called `probabilistic modified trends' (PMT) methodology (Heijden, et al., 2002).\nIn this article we will present and characterize the three major schools or techniques of Scenario Planning identified by Bradfield et al. (20052): “Intuitive Logics”, the “Probabilistic Modified Trends” and the “La Prospective” methodologies. \n","downloadable_attachments":[{"id":67448908,"asset_id":49058360,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":131109111,"first_name":"Paulo","last_name":"Soeiro Carvalho","domain_name":"ulisboa","page_name":"PauloSoeiroCarvalho","display_name":"Paulo Soeiro Carvalho","profile_url":"https://ulisboa.academia.edu/PauloSoeiroCarvalho?f_ri=62112","photo":"https://0.academia-photos.com/131109111/52125183/40224263/s65_paulo.soeiro_carvalho.jpg"}],"research_interests":[{"id":3477,"name":"Strategic Foresight","url":"https://www.academia.edu/Documents/in/Strategic_Foresight?f_ri=62112","nofollow":true},{"id":5009,"name":"Strategic Management","url":"https://www.academia.edu/Documents/in/Strategic_Management?f_ri=62112","nofollow":true},{"id":17581,"name":"Futures Studies","url":"https://www.academia.edu/Documents/in/Futures_Studies?f_ri=62112","nofollow":true},{"id":18289,"name":"Scenario planning","url":"https://www.academia.edu/Documents/in/Scenario_planning?f_ri=62112","nofollow":true},{"id":36260,"name":"Futures Studies and Foresight","url":"https://www.academia.edu/Documents/in/Futures_Studies_and_Foresight?f_ri=62112"},{"id":46271,"name":"Strategy","url":"https://www.academia.edu/Documents/in/Strategy?f_ri=62112"},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112"},{"id":187905,"name":"Scenarios","url":"https://www.academia.edu/Documents/in/Scenarios?f_ri=62112"},{"id":300353,"name":"Prospectiva","url":"https://www.academia.edu/Documents/in/Prospectiva?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_3355680" data-work_id="3355680" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/3355680/Type_2_d%C4%B1abetes_mell%C4%B1tus_and_CA_19_9_levels">Type 2 dıabetes mellıtus and CA 19-9 levels</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">5331 Right liver lobe/albumin ratio: Contribution to non-invasive assessment of portal hypertension Alempijevic T, 5336 Liver biopsy in a district general hospital: Changes over two decades Syn WK, Bruckner-Holt C, Farmer A, Howdle S,... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_3355680" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">5331 Right liver lobe/albumin ratio: Contribution to non-invasive assessment of portal hypertension Alempijevic T, 5336 Liver biopsy in a district general hospital: Changes over two decades Syn WK, Bruckner-Holt C, Farmer A, Howdle S, Bateman J 5343 Effects of a 24-week course of interferon-a therapy after curative treatment of hepatitis C virus-associated hepatocellular carcinoma 5351 Pancreatic fistula after pancreaticoduodenectomy: A comparison between the two pancreaticojejunostomy methods for approximating the pancreatic parenchyma to the jejunal seromuscular layer: Interrupted vs continuous stitches Lee SE, Yang SH, Jang JY, Kim SW 5357 Type 2 dıabetes mellıtus and CA 19-9 levels Uygur-Bayramiçli O, Dabak R, Orbay E, Dolapçıoğlu C, Sargın M, Kılıçoğlu G, Güleryüzlü Y, Mayadağlı A 5360 Holistic Acupuncture approach to idiopathic refractory nausea, abdominal pain and bloating Ouyang A, Xu L CLINICAL RESEARCH VIRAL HEPATITIS REVIEW World Journal of Gastroenterology </div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/3355680" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="4a963b67846098e4b61c2601250f651c" rel="nofollow" data-download="{"attachment_id":31165625,"asset_id":3355680,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/31165625/download_file?st=MTczOTgwMzc0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="3892573" href="https://independent.academia.edu/GamzeSarg%C4%B1n">Gamze Sargın</a><script data-card-contents-for-user="3892573" type="text/json">{"id":3892573,"first_name":"Gamze","last_name":"Sargın","domain_name":"independent","page_name":"GamzeSargın","display_name":"Gamze Sargın","profile_url":"https://independent.academia.edu/GamzeSarg%C4%B1n?f_ri=62112","photo":"https://0.academia-photos.com/3892573/1441051/1764396/s65_gamze.sarg_n.jpg"}</script></span></span></li><li class="js-paper-rank-work_3355680 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="3355680"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 3355680, container: ".js-paper-rank-work_3355680", }); });</script></li><li class="js-percentile-work_3355680 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 3355680; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_3355680"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_3355680 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="3355680"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 3355680; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=3355680]").text(description); $(".js-view-count-work_3355680").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_3355680").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="3355680"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">13</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a>, <script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="71300" rel="nofollow" href="https://www.academia.edu/Documents/in/Blood_Glucose">Blood Glucose</a>, <script data-card-contents-for-ri="71300" type="text/json">{"id":71300,"name":"Blood Glucose","url":"https://www.academia.edu/Documents/in/Blood_Glucose?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="71511" rel="nofollow" href="https://www.academia.edu/Documents/in/Diabetes_mellitus">Diabetes mellitus</a>, <script data-card-contents-for-ri="71511" type="text/json">{"id":71511,"name":"Diabetes mellitus","url":"https://www.academia.edu/Documents/in/Diabetes_mellitus?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="73606" rel="nofollow" href="https://www.academia.edu/Documents/in/World">World</a><script data-card-contents-for-ri="73606" type="text/json">{"id":73606,"name":"World","url":"https://www.academia.edu/Documents/in/World?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=3355680]'), work: {"id":3355680,"title":"Type 2 dıabetes mellıtus and CA 19-9 levels","created_at":"2013-04-22T02:51:06.217-07:00","url":"https://www.academia.edu/3355680/Type_2_d%C4%B1abetes_mell%C4%B1tus_and_CA_19_9_levels?f_ri=62112","dom_id":"work_3355680","summary":"5331 Right liver lobe/albumin ratio: Contribution to non-invasive assessment of portal hypertension Alempijevic T, 5336 Liver biopsy in a district general hospital: Changes over two decades Syn WK, Bruckner-Holt C, Farmer A, Howdle S, Bateman J 5343 Effects of a 24-week course of interferon-a therapy after curative treatment of hepatitis C virus-associated hepatocellular carcinoma 5351 Pancreatic fistula after pancreaticoduodenectomy: A comparison between the two pancreaticojejunostomy methods for approximating the pancreatic parenchyma to the jejunal seromuscular layer: Interrupted vs continuous stitches Lee SE, Yang SH, Jang JY, Kim SW 5357 Type 2 dıabetes mellıtus and CA 19-9 levels Uygur-Bayramiçli O, Dabak R, Orbay E, Dolapçıoğlu C, Sargın M, Kılıçoğlu G, Güleryüzlü Y, Mayadağlı A 5360 Holistic Acupuncture approach to idiopathic refractory nausea, abdominal pain and bloating Ouyang A, Xu L CLINICAL RESEARCH VIRAL HEPATITIS REVIEW World Journal of Gastroenterology ","downloadable_attachments":[{"id":31165625,"asset_id":3355680,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":3892573,"first_name":"Gamze","last_name":"Sargın","domain_name":"independent","page_name":"GamzeSargın","display_name":"Gamze Sargın","profile_url":"https://independent.academia.edu/GamzeSarg%C4%B1n?f_ri=62112","photo":"https://0.academia-photos.com/3892573/1441051/1764396/s65_gamze.sarg_n.jpg"}],"research_interests":[{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":71300,"name":"Blood Glucose","url":"https://www.academia.edu/Documents/in/Blood_Glucose?f_ri=62112","nofollow":true},{"id":71511,"name":"Diabetes mellitus","url":"https://www.academia.edu/Documents/in/Diabetes_mellitus?f_ri=62112","nofollow":true},{"id":73606,"name":"World","url":"https://www.academia.edu/Documents/in/World?f_ri=62112","nofollow":true},{"id":92788,"name":"Pancreas","url":"https://www.academia.edu/Documents/in/Pancreas?f_ri=62112"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=62112"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112"},{"id":568482,"name":"Biological markers","url":"https://www.academia.edu/Documents/in/Biological_markers?f_ri=62112"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=62112"},{"id":915951,"name":"Type 2 Diabetes Mellitus","url":"https://www.academia.edu/Documents/in/Type_2_Diabetes_Mellitus?f_ri=62112"},{"id":959921,"name":"X ray Computed Tomography","url":"https://www.academia.edu/Documents/in/X_ray_Computed_Tomography?f_ri=62112"},{"id":1318932,"name":"Predictive value of tests","url":"https://www.academia.edu/Documents/in/Predictive_value_of_tests?f_ri=62112"},{"id":1819399,"name":"Case Control Studies","url":"https://www.academia.edu/Documents/in/Case_Control_Studies?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_4617202" data-work_id="4617202" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/4617202/High_Resolution_Computed_Tomography_of_Temporal_Bone_Part_III_Axial_Postoperative_Anatomy">High-Resolution Computed Tomography of Temporal Bone: Part III: Axial Postoperative Anatomy</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Pathologic conditions involving the temporal bone in infants and children are now commonly diagnosed by computed tomography (CT). The importance of utilizing high resolution computed tomography (HRCT) with magnified, thin (1.5 mm) scans... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_4617202" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Pathologic conditions involving the temporal bone in infants and children are now commonly diagnosed by computed tomography (CT). The importance of utilizing high resolution computed tomography (HRCT) with magnified, thin (1.5 mm) scans in both the axial and coronal planes is stressed in order to obtain the maximal anatomic information that is critical for proper diagnosis. A retrospective analysis of 388 cases reveals a positive diagnostic yield ranging from 65% in temporal bone trauma to 20% in clinically suspected neoplasm. Selected case reports of congenital abnormalities, inflammatory processes, traumatic lesions, and tumors will be presented. We conclude that HRCT is an excellent diagnostic modality and should be used liberally to evaluate the temporal bone in children.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/4617202" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="7d914e7e6e168c5086054851f87ed2ce" rel="nofollow" data-download="{"attachment_id":49754590,"asset_id":4617202,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/49754590/download_file?st=MTczOTgwMzc0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="5821515" href="https://dkfz.academia.edu/SoenkeBartling">Soenke Bartling</a><script data-card-contents-for-user="5821515" type="text/json">{"id":5821515,"first_name":"Soenke","last_name":"Bartling","domain_name":"dkfz","page_name":"SoenkeBartling","display_name":"Soenke Bartling","profile_url":"https://dkfz.academia.edu/SoenkeBartling?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_4617202 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="4617202"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 4617202, container: ".js-paper-rank-work_4617202", }); 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$(".js-view-count[data-work-id=4617202]").text(description); $(".js-view-count-work_4617202").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_4617202").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="4617202"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">16</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a>, <script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="64933" rel="nofollow" href="https://www.academia.edu/Documents/in/Child">Child</a>, <script data-card-contents-for-ri="64933" type="text/json">{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="134346" rel="nofollow" href="https://www.academia.edu/Documents/in/Infant">Infant</a><script data-card-contents-for-ri="134346" type="text/json">{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=4617202]'), work: {"id":4617202,"title":"High-Resolution Computed Tomography of Temporal Bone: Part III: Axial Postoperative Anatomy","created_at":"2013-09-29T00:18:29.331-07:00","url":"https://www.academia.edu/4617202/High_Resolution_Computed_Tomography_of_Temporal_Bone_Part_III_Axial_Postoperative_Anatomy?f_ri=62112","dom_id":"work_4617202","summary":"Pathologic conditions involving the temporal bone in infants and children are now commonly diagnosed by computed tomography (CT). The importance of utilizing high resolution computed tomography (HRCT) with magnified, thin (1.5 mm) scans in both the axial and coronal planes is stressed in order to obtain the maximal anatomic information that is critical for proper diagnosis. A retrospective analysis of 388 cases reveals a positive diagnostic yield ranging from 65% in temporal bone trauma to 20% in clinically suspected neoplasm. Selected case reports of congenital abnormalities, inflammatory processes, traumatic lesions, and tumors will be presented. We conclude that HRCT is an excellent diagnostic modality and should be used liberally to evaluate the temporal bone in children.","downloadable_attachments":[{"id":49754590,"asset_id":4617202,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":5821515,"first_name":"Soenke","last_name":"Bartling","domain_name":"dkfz","page_name":"SoenkeBartling","display_name":"Soenke Bartling","profile_url":"https://dkfz.academia.edu/SoenkeBartling?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective 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Specificity","url":"https://www.academia.edu/Documents/in/Sensitivity_and_Specificity?f_ri=62112"},{"id":959921,"name":"X ray Computed Tomography","url":"https://www.academia.edu/Documents/in/X_ray_Computed_Tomography?f_ri=62112"},{"id":1000427,"name":"Reference Values","url":"https://www.academia.edu/Documents/in/Reference_Values?f_ri=62112"},{"id":1198057,"name":"Computer","url":"https://www.academia.edu/Documents/in/Computer?f_ri=62112"},{"id":1253980,"name":"Cochlear Implantation","url":"https://www.academia.edu/Documents/in/Cochlear_Implantation?f_ri=62112"},{"id":1275883,"name":"*Radiographic Image Enhancement","url":"https://www.academia.edu/Documents/in/_Radiographic_Image_Enhancement?f_ri=62112"},{"id":2489700,"name":"Child preschool","url":"https://www.academia.edu/Documents/in/Child_preschool?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_14231020" data-work_id="14231020" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/14231020/The_Consensus_Sleep_Diary_Standardizing_Prospective_Sleep_Self_Monitoring">The Consensus Sleep Diary: Standardizing Prospective Sleep Self-Monitoring</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">estimate treatment effect sizes. 5-8 However, these effect size estimates were based on data from a variety of sleep diaries with distinctive instructional sets and inconsistent definitions of target sleep measures.</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/14231020" 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class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33206400" href="https://independent.academia.edu/KennethLichstein">Kenneth Lichstein</a><script data-card-contents-for-user="33206400" type="text/json">{"id":33206400,"first_name":"Kenneth","last_name":"Lichstein","domain_name":"independent","page_name":"KennethLichstein","display_name":"Kenneth Lichstein","profile_url":"https://independent.academia.edu/KennethLichstein?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_14231020 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="14231020"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 14231020, container: ".js-paper-rank-work_14231020", }); });</script></li><li class="js-percentile-work_14231020 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14231020; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_14231020"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_14231020 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="14231020"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14231020; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14231020]").text(description); $(".js-view-count-work_14231020").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_14231020").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="14231020"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">12</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="4193" rel="nofollow" href="https://www.academia.edu/Documents/in/Focus_Groups">Focus Groups</a>, <script data-card-contents-for-ri="4193" type="text/json">{"id":4193,"name":"Focus Groups","url":"https://www.academia.edu/Documents/in/Focus_Groups?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="47884" rel="nofollow" href="https://www.academia.edu/Documents/in/Biological_Sciences">Biological Sciences</a>, <script data-card-contents-for-ri="47884" type="text/json">{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a><script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=14231020]'), work: {"id":14231020,"title":"The Consensus Sleep Diary: Standardizing Prospective Sleep Self-Monitoring","created_at":"2015-07-20T14:21:35.271-07:00","url":"https://www.academia.edu/14231020/The_Consensus_Sleep_Diary_Standardizing_Prospective_Sleep_Self_Monitoring?f_ri=62112","dom_id":"work_14231020","summary":"estimate treatment effect sizes. 5-8 However, these effect size estimates were based on data from a variety of sleep diaries with distinctive instructional sets and inconsistent definitions of target sleep measures.","downloadable_attachments":[{"id":44429536,"asset_id":14231020,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33206400,"first_name":"Kenneth","last_name":"Lichstein","domain_name":"independent","page_name":"KennethLichstein","display_name":"Kenneth Lichstein","profile_url":"https://independent.academia.edu/KennethLichstein?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":4193,"name":"Focus Groups","url":"https://www.academia.edu/Documents/in/Focus_Groups?f_ri=62112","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112","nofollow":true},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":83306,"name":"Consensus","url":"https://www.academia.edu/Documents/in/Consensus?f_ri=62112"},{"id":106431,"name":"Sleep disorders","url":"https://www.academia.edu/Documents/in/Sleep_disorders?f_ri=62112"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=62112"},{"id":133324,"name":"Sleep","url":"https://www.academia.edu/Documents/in/Sleep?f_ri=62112"},{"id":182342,"name":"Personal Health Records / Clouds","url":"https://www.academia.edu/Documents/in/Personal_Health_Records_Clouds?f_ri=62112"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=62112"},{"id":327850,"name":"Questionnaires","url":"https://www.academia.edu/Documents/in/Questionnaires?f_ri=62112"},{"id":1030142,"name":"Self report","url":"https://www.academia.edu/Documents/in/Self_report?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_53270481" data-work_id="53270481" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/53270481/Effects_of_Qigong_in_patients_with_burnout_A_randomized_controlled_trial">Effects of Qigong in patients with burnout: A randomized controlled trial</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objective: To evaluate the efficacy of Qigong in rehabili tation for patients with burnout. Design: Prospective, randomized controlled trial. Subjects: Eighty-two patients (68 women and 14 men, mean age 44.3 (standard deviation 9.1)... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_53270481" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objective: To evaluate the efficacy of Qigong in rehabili tation for patients with burnout. Design: Prospective, randomized controlled trial. Subjects: Eighty-two patients (68 women and 14 men, mean age 44.3 (standard deviation 9.1) years) diagnosed with burnout. Methods: Basic care was offered to both the intervention and the control group. Patients in the intervention group received basic care and, in addition, performed Qigong twice a week for 12 weeks. Psychological variables, health-related quality of life, perceived relaxation and physical measurements were assessed at baseline and after the intervention period. Results: No significant difference in treatment efficacy between the groups was found by either intention-to-treat or per-protocol analyses. Both groups improved significantly over time, with reduced levels of burnout, fatigue, anxiety and depression, and increased dynamic balance and physical capacity. Conclusion: In this study, a Qigong intervention twice a week for 12 weeks had no additional effect beyond basic care for patients with burnout.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/53270481" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="d065b8f439589854507f2072f38f9439" rel="nofollow" data-download="{"attachment_id":70164473,"asset_id":53270481,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/70164473/download_file?st=MTczOTgwMzc0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33957605" href="https://umu.academia.edu/ChristinaAhlgren">Christina Ahlgren</a><script data-card-contents-for-user="33957605" type="text/json">{"id":33957605,"first_name":"Christina","last_name":"Ahlgren","domain_name":"umu","page_name":"ChristinaAhlgren","display_name":"Christina Ahlgren","profile_url":"https://umu.academia.edu/ChristinaAhlgren?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_53270481 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="53270481"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 53270481, container: ".js-paper-rank-work_53270481", }); 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$(".js-view-count[data-work-id=53270481]").text(description); $(".js-view-count-work_53270481").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_53270481").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="53270481"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">7</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="641" rel="nofollow" href="https://www.academia.edu/Documents/in/Rehabilitation_Medicine">Rehabilitation Medicine</a>, <script data-card-contents-for-ri="641" type="text/json">{"id":641,"name":"Rehabilitation Medicine","url":"https://www.academia.edu/Documents/in/Rehabilitation_Medicine?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="7470" rel="nofollow" href="https://www.academia.edu/Documents/in/Quality_of_life">Quality of life</a>, <script data-card-contents-for-ri="7470" type="text/json">{"id":7470,"name":"Quality of life","url":"https://www.academia.edu/Documents/in/Quality_of_life?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="12426" rel="nofollow" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a>, <script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a><script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=53270481]'), work: {"id":53270481,"title":"Effects of Qigong in patients with burnout: A randomized controlled trial","created_at":"2021-09-23T14:01:04.958-07:00","url":"https://www.academia.edu/53270481/Effects_of_Qigong_in_patients_with_burnout_A_randomized_controlled_trial?f_ri=62112","dom_id":"work_53270481","summary":"Objective: To evaluate the efficacy of Qigong in rehabili tation for patients with burnout. Design: Prospective, randomized controlled trial. Subjects: Eighty-two patients (68 women and 14 men, mean age 44.3 (standard deviation 9.1) years) diagnosed with burnout. Methods: Basic care was offered to both the intervention and the control group. Patients in the intervention group received basic care and, in addition, performed Qigong twice a week for 12 weeks. Psychological variables, health-related quality of life, perceived relaxation and physical measurements were assessed at baseline and after the intervention period. Results: No significant difference in treatment efficacy between the groups was found by either intention-to-treat or per-protocol analyses. Both groups improved significantly over time, with reduced levels of burnout, fatigue, anxiety and depression, and increased dynamic balance and physical capacity. Conclusion: In this study, a Qigong intervention twice a week for 12 weeks had no additional effect beyond basic care for patients with burnout.","downloadable_attachments":[{"id":70164473,"asset_id":53270481,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33957605,"first_name":"Christina","last_name":"Ahlgren","domain_name":"umu","page_name":"ChristinaAhlgren","display_name":"Christina Ahlgren","profile_url":"https://umu.academia.edu/ChristinaAhlgren?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":641,"name":"Rehabilitation Medicine","url":"https://www.academia.edu/Documents/in/Rehabilitation_Medicine?f_ri=62112","nofollow":true},{"id":7470,"name":"Quality of life","url":"https://www.academia.edu/Documents/in/Quality_of_life?f_ri=62112","nofollow":true},{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112"},{"id":413196,"name":"Randomized Controlled Trial","url":"https://www.academia.edu/Documents/in/Randomized_Controlled_Trial?f_ri=62112"},{"id":3464648,"name":"Breathing exercises","url":"https://www.academia.edu/Documents/in/Breathing_exercises?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_14523378 coauthored" data-work_id="14523378" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/14523378/Migrainous_vertigo_clinical_oculographic_and_posturographic_findings">Migrainous vertigo: clinical, oculographic and posturographic findings</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Migrainous vertigo (MV) is accepted as a common cause of episodic vertigo. The peripheral or central vestibular localization of the deficit as well as the pathophysiology is unclear. This prospective study was designed to assess the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_14523378" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Migrainous vertigo (MV) is accepted as a common cause of episodic vertigo. The peripheral or central vestibular localization of the deficit as well as the pathophysiology is unclear. This prospective study was designed to assess the clinical features of MV and to search for the localization of the vestibular pathology. Thirty-five patients with MV, 20 patients with migraine and 20 healthy volunteers were studied. Comprehensive neurotological tests were performed between attacks. None of the normal controls or the patients with migraine had ocular motor deficits or caloric test abnormalities. Three patients in the MV group showed saccadic pursuit (8.6%), in one of whom saccadic hypometria was also present. Caloric test results revealed unilateral caloric hypofunction in seven patients (20%). Static posturography results revealed increased sway velocity when the eyes were closed or the platform was distorted in patients with MV. These findings during the symptom-free period revealed that peripheral vestibular dysfunction was more common than a central deficit. ᮀ Migraine, migrainous vertigo, posturography, video-oculography Neşe Çelebisoy MD,</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/14523378" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="0dfbc5eebcb343a5bf8a1d69d8cb117e" rel="nofollow" data-download="{"attachment_id":44093140,"asset_id":14523378,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44093140/download_file?st=MTczOTgwMzc0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33564154" href="https://ege.academia.edu/FG%C3%B6k%C3%A7ay">F. Gökçay</a><script data-card-contents-for-user="33564154" type="text/json">{"id":33564154,"first_name":"F.","last_name":"Gökçay","domain_name":"ege","page_name":"FGökçay","display_name":"F. Gökçay","profile_url":"https://ege.academia.edu/FG%C3%B6k%C3%A7ay?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-14523378">+1</span><div class="hidden js-additional-users-14523378"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://ege.academia.edu/Ne%C5%9Fe%C3%87elebisoy">Neşe Çelebisoy</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-14523378'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-14523378').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_14523378 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="14523378"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 14523378, container: ".js-paper-rank-work_14523378", }); });</script></li><li class="js-percentile-work_14523378 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14523378; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_14523378"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_14523378 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="14523378"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14523378; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14523378]").text(description); $(".js-view-count-work_14523378").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_14523378").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="14523378"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">7</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a>, <script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="221430" rel="nofollow" href="https://www.academia.edu/Documents/in/Vertigo">Vertigo</a>, <script data-card-contents-for-ri="221430" type="text/json">{"id":221430,"name":"Vertigo","url":"https://www.academia.edu/Documents/in/Vertigo?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="228356" rel="nofollow" href="https://www.academia.edu/Documents/in/Posture">Posture</a><script data-card-contents-for-ri="228356" type="text/json">{"id":228356,"name":"Posture","url":"https://www.academia.edu/Documents/in/Posture?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=14523378]'), work: {"id":14523378,"title":"Migrainous vertigo: clinical, oculographic and posturographic findings","created_at":"2015-07-30T22:04:21.040-07:00","url":"https://www.academia.edu/14523378/Migrainous_vertigo_clinical_oculographic_and_posturographic_findings?f_ri=62112","dom_id":"work_14523378","summary":"Migrainous vertigo (MV) is accepted as a common cause of episodic vertigo. The peripheral or central vestibular localization of the deficit as well as the pathophysiology is unclear. This prospective study was designed to assess the clinical features of MV and to search for the localization of the vestibular pathology. Thirty-five patients with MV, 20 patients with migraine and 20 healthy volunteers were studied. Comprehensive neurotological tests were performed between attacks. None of the normal controls or the patients with migraine had ocular motor deficits or caloric test abnormalities. Three patients in the MV group showed saccadic pursuit (8.6%), in one of whom saccadic hypometria was also present. Caloric test results revealed unilateral caloric hypofunction in seven patients (20%). Static posturography results revealed increased sway velocity when the eyes were closed or the platform was distorted in patients with MV. These findings during the symptom-free period revealed that peripheral vestibular dysfunction was more common than a central deficit. ᮀ Migraine, migrainous vertigo, posturography, video-oculography Neşe Çelebisoy MD,","downloadable_attachments":[{"id":44093140,"asset_id":14523378,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33564154,"first_name":"F.","last_name":"Gökçay","domain_name":"ege","page_name":"FGökçay","display_name":"F. Gökçay","profile_url":"https://ege.academia.edu/FG%C3%B6k%C3%A7ay?f_ri=62112","photo":"/images/s65_no_pic.png"},{"id":33478849,"first_name":"Neşe","last_name":"Çelebisoy","domain_name":"ege","page_name":"NeşeÇelebisoy","display_name":"Neşe Çelebisoy","profile_url":"https://ege.academia.edu/Ne%C5%9Fe%C3%87elebisoy?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":221430,"name":"Vertigo","url":"https://www.academia.edu/Documents/in/Vertigo?f_ri=62112","nofollow":true},{"id":228356,"name":"Posture","url":"https://www.academia.edu/Documents/in/Posture?f_ri=62112","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=62112"},{"id":1312754,"name":"Prospective Study","url":"https://www.academia.edu/Documents/in/Prospective_Study?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_20132238" data-work_id="20132238" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/20132238/Visual_outcome_and_patient_satisfaction_after_multifocal_intraocular_lens_implantation_Aspheric_versus_spherical_design">Visual outcome and patient satisfaction after multifocal intraocular lens implantation: Aspheric versus spherical design</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">PURPOSE: To evaluate visual outcomes and patient satisfaction after implantation of an aspheric apodized diffractive intraocular lens (IOL) or a spherical apodized diffractive IOL in cataract surgery.</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/20132238" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="deee092b482197fb0696572064adadfb" rel="nofollow" data-download="{"attachment_id":41217805,"asset_id":20132238,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/41217805/download_file?st=MTczOTgwMzc0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="41208025" href="https://independent.academia.edu/CarrollWebers">Carroll Webers</a><script data-card-contents-for-user="41208025" 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Webers","profile_url":"https://independent.academia.edu/CarrollWebers?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":40271,"name":"Visual acuity","url":"https://www.academia.edu/Documents/in/Visual_acuity?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":135373,"name":"Contrast sensitivity","url":"https://www.academia.edu/Documents/in/Contrast_sensitivity?f_ri=62112","nofollow":true},{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies?f_ri=62112","nofollow":true},{"id":144034,"name":"Cataract","url":"https://www.academia.edu/Documents/in/Cataract?f_ri=62112"},{"id":144052,"name":"Patient 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itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/25853794/Technical_Refinements_and_Results_in_Full_Right_Full_Left_Splitting_of_the_Deceased_Donor_Liver">Technical Refinements and Results in Full-Right Full-Left Splitting of the Deceased Donor Liver</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objective: Splitting of the liver at the line of Cantlie of otherwise healthy people is accepted worldwide as a reasonable procedure for the donors in adult living donor liver transplantation. A similar operation is still considered as... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_25853794" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objective: Splitting of the liver at the line of Cantlie of otherwise healthy people is accepted worldwide as a reasonable procedure for the donors in adult living donor liver transplantation. A similar operation is still considered as experimental if performed in the deceased donor liver. The aim of this study is to evaluate the technical evolution and the results of this variant splitting technique. Patients and Methods: From January 1999 to August 2004, a total of 35 transplants of hemilivers from deceased donors (segments V-VIII: n ϭ 16 and segments (I)II-IV: n ϭ 19) were performed in our center. Seven splits were performed in situ and 12 ex situ. Splitting of the vena cava was applied in 18 splits and splitting of the middle hepatic vein in 8. Seven adults and 12 adolescents received the left hemiliver with a mean age of 12 years (range, 3-64 years), of whom 21% were UNOS status 1. Recipients of right hemilivers were exclusively adults with a mean age of 48 years (range, 31-65 years), none of them were high urgent. The outcome of these 35 recipients of hemilivers was prospectively evaluated. Results: Mean deceased donor age was 27 years (range, 12-57 years), the donor's body weight ranged between 55 kg and 100 kg. The mean weight of the right and left hemilivers was 1135 g (range, 745-1432 g) and 602 g (range, 289 -1100 g), respectively. The mean graft recipient weight ratio in left and right hemiliver group was 1.46% (range, 0.88%-3.54%) and 1.58% (range, 1.15%-1.99%), respectively. Median follow-up was 27.4 months (range, 1-68.3 months). Four patients died (actual patient survival FR group: 87.5% versus FL group: 89.5%), 3 due to septic MOF and 1 due to graft versus host disease. In each of the 2 groups, 2 recipients had to undergo retransplantation, which resulted in an actual right and left hemiliver survival rate of 75% and 84%, respectively. The causes for retransplantation were primary nonfunction in 2 left hemilivers, chronic graft dysfunction in 1 right hemiliver, and recurrence of the primary disease in 1 recipient of a right hemiliver. Primary poor function was observed in 1 recipient of a right hemiliver. Early and late biliary complications occurred in both right and left hemiliver groups at the rate of 37.5% (n ϭ 6) and 21% (n ϭ 4), respectively. Arterial, portal, and venous complications were not observed in either group. Conclusion: The technical development of splitting along Cantlie's line is almost complete with the last challenge being the reduction of biliary complications. The key to success is the choice of adequate deceased donors and recipients. Full-right full-left splitting is safely possible and should be considered as a reasonable instrument to alleviate mortality on the adult waiting list and to reduce the need for adult and adolescent living donation. (Ann Surg 2005;242: 802-813) From the *Numbers indicate the consecutive number of the splitting procedure. L indicates left hemiliver; R, right hemiliver.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/25853794" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="6580b336ab65d032244381caefe0c11f" rel="nofollow" data-download="{"attachment_id":46220873,"asset_id":25853794,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46220873/download_file?st=MTczOTgwMzc0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="49567784" href="https://independent.academia.edu/DieterBroering">Dieter Broering</a><script data-card-contents-for-user="49567784" type="text/json">{"id":49567784,"first_name":"Dieter","last_name":"Broering","domain_name":"independent","page_name":"DieterBroering","display_name":"Dieter Broering","profile_url":"https://independent.academia.edu/DieterBroering?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_25853794 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="25853794"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 25853794, container: ".js-paper-rank-work_25853794", }); 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A similar operation is still considered as experimental if performed in the deceased donor liver. The aim of this study is to evaluate the technical evolution and the results of this variant splitting technique. Patients and Methods: From January 1999 to August 2004, a total of 35 transplants of hemilivers from deceased donors (segments V-VIII: n ϭ 16 and segments (I)II-IV: n ϭ 19) were performed in our center. Seven splits were performed in situ and 12 ex situ. Splitting of the vena cava was applied in 18 splits and splitting of the middle hepatic vein in 8. Seven adults and 12 adolescents received the left hemiliver with a mean age of 12 years (range, 3-64 years), of whom 21% were UNOS status 1. Recipients of right hemilivers were exclusively adults with a mean age of 48 years (range, 31-65 years), none of them were high urgent. The outcome of these 35 recipients of hemilivers was prospectively evaluated. Results: Mean deceased donor age was 27 years (range, 12-57 years), the donor's body weight ranged between 55 kg and 100 kg. The mean weight of the right and left hemilivers was 1135 g (range, 745-1432 g) and 602 g (range, 289 -1100 g), respectively. The mean graft recipient weight ratio in left and right hemiliver group was 1.46% (range, 0.88%-3.54%) and 1.58% (range, 1.15%-1.99%), respectively. Median follow-up was 27.4 months (range, 1-68.3 months). Four patients died (actual patient survival FR group: 87.5% versus FL group: 89.5%), 3 due to septic MOF and 1 due to graft versus host disease. In each of the 2 groups, 2 recipients had to undergo retransplantation, which resulted in an actual right and left hemiliver survival rate of 75% and 84%, respectively. The causes for retransplantation were primary nonfunction in 2 left hemilivers, chronic graft dysfunction in 1 right hemiliver, and recurrence of the primary disease in 1 recipient of a right hemiliver. Primary poor function was observed in 1 recipient of a right hemiliver. Early and late biliary complications occurred in both right and left hemiliver groups at the rate of 37.5% (n ϭ 6) and 21% (n ϭ 4), respectively. Arterial, portal, and venous complications were not observed in either group. Conclusion: The technical development of splitting along Cantlie's line is almost complete with the last challenge being the reduction of biliary complications. The key to success is the choice of adequate deceased donors and recipients. Full-right full-left splitting is safely possible and should be considered as a reasonable instrument to alleviate mortality on the adult waiting list and to reduce the need for adult and adolescent living donation. (Ann Surg 2005;242: 802-813) From the *Numbers indicate the consecutive number of the splitting procedure. L indicates left hemiliver; R, right hemiliver.","downloadable_attachments":[{"id":46220873,"asset_id":25853794,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":49567784,"first_name":"Dieter","last_name":"Broering","domain_name":"independent","page_name":"DieterBroering","display_name":"Dieter Broering","profile_url":"https://independent.academia.edu/DieterBroering?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":3243,"name":"Nonparametric Statistics","url":"https://www.academia.edu/Documents/in/Nonparametric_Statistics?f_ri=62112","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=62112","nofollow":true},{"id":71437,"name":"Liver","url":"https://www.academia.edu/Documents/in/Liver?f_ri=62112"},{"id":155901,"name":"Liver Transplantation","url":"https://www.academia.edu/Documents/in/Liver_Transplantation?f_ri=62112"},{"id":247948,"name":"Cadaver","url":"https://www.academia.edu/Documents/in/Cadaver?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_22162388" data-work_id="22162388" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/22162388/Treatment_of_complex_fractures_of_the_distal_radius_A_prospective_randomised_comparison_of_external_fixation_versus_locked_volar_plating">Treatment of complex fractures of the distal radius: A prospective randomised comparison of external fixation ‘versus’ locked volar plating</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/22162388" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a32c5d55cd614556c07d5edc81ba663c" rel="nofollow" data-download="{"attachment_id":42825215,"asset_id":22162388,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42825215/download_file?st=MTczOTgwMzc0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="43511920" href="https://independent.academia.edu/PMassin">Philippe Massin</a><script data-card-contents-for-user="43511920" type="text/json">{"id":43511920,"first_name":"Philippe","last_name":"Massin","domain_name":"independent","page_name":"PMassin","display_name":"Philippe Massin","profile_url":"https://independent.academia.edu/PMassin?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_22162388 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="22162388"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 22162388, container: ".js-paper-rank-work_22162388", }); 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$(".js-view-count[data-work-id=22162388]").text(description); $(".js-view-count-work_22162388").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_22162388").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="22162388"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">12</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="588" rel="nofollow" href="https://www.academia.edu/Documents/in/Nursing">Nursing</a>, <script data-card-contents-for-ri="588" type="text/json">{"id":588,"name":"Nursing","url":"https://www.academia.edu/Documents/in/Nursing?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="12426" rel="nofollow" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a>, <script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a>, <script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="80562" rel="nofollow" href="https://www.academia.edu/Documents/in/Injury">Injury</a><script data-card-contents-for-ri="80562" type="text/json">{"id":80562,"name":"Injury","url":"https://www.academia.edu/Documents/in/Injury?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=22162388]'), work: {"id":22162388,"title":"Treatment of complex fractures of the distal radius: A prospective randomised comparison of external fixation ‘versus’ locked volar plating","created_at":"2016-02-18T22:36:18.300-08:00","url":"https://www.academia.edu/22162388/Treatment_of_complex_fractures_of_the_distal_radius_A_prospective_randomised_comparison_of_external_fixation_versus_locked_volar_plating?f_ri=62112","dom_id":"work_22162388","summary":null,"downloadable_attachments":[{"id":42825215,"asset_id":22162388,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":43511920,"first_name":"Philippe","last_name":"Massin","domain_name":"independent","page_name":"PMassin","display_name":"Philippe Massin","profile_url":"https://independent.academia.edu/PMassin?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":588,"name":"Nursing","url":"https://www.academia.edu/Documents/in/Nursing?f_ri=62112","nofollow":true},{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":80562,"name":"Injury","url":"https://www.academia.edu/Documents/in/Injury?f_ri=62112","nofollow":true},{"id":125564,"name":"Statistical Significance","url":"https://www.academia.edu/Documents/in/Statistical_Significance?f_ri=62112"},{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies?f_ri=62112"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=62112"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=62112"},{"id":546419,"name":"Age Factors","url":"https://www.academia.edu/Documents/in/Age_Factors?f_ri=62112"},{"id":1142792,"name":"Fracture Fixation","url":"https://www.academia.edu/Documents/in/Fracture_Fixation?f_ri=62112"},{"id":1312233,"name":"External Fixators","url":"https://www.academia.edu/Documents/in/External_Fixators?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_37040032" data-work_id="37040032" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/37040032/Prospectiva_en_Am%C3%A9rica_Latina_Aprendizajes_a_partir_de_la_pr%C3%A1ctica_SEMINARIOS_Y_CONFERENCIAS_No_88">Prospectiva en América Latina. Aprendizajes a partir de la práctica. SEMINARIOS Y CONFERENCIAS No.88</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Esta publicación es producto de la selección y edición de los mejores trabajos presentados durante las Terceras Jornadas de Planificación para el Desarrollo, que se celebraron en paralelo con el seminario internacional “Los Objetivos de... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_37040032" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Esta publicación es producto de la selección y edición de los mejores trabajos presentados durante las Terceras Jornadas de Planificación para el Desarrollo, que se celebraron en paralelo con el seminario internacional “Los Objetivos de Desarrollo Sostenible y la Construcción de Futuros para América Latina y el Caribe”, organizado en Santiago de Chile, del 18 al 20 de mayo de 2016, por el Instituto Latinoamericano y del Caribe de Planificación Económica y Social (ILPES) de la Comisión Económica para América Latina y el Caribe (CEPAL). Este seminario se desarrolló en el marco de las actividades del convenio de cooperación técnica entre la CEPAL y la República de Corea.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/37040032" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="05d7a736eb439a7799a653158d7fcb4c" rel="nofollow" data-download="{"attachment_id":56990381,"asset_id":37040032,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/56990381/download_file?st=MTczOTgwMzc0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="9001556" href="https://cepal.academia.edu/MauricioCuervo">Mauricio Cuervo</a><script data-card-contents-for-user="9001556" type="text/json">{"id":9001556,"first_name":"Mauricio","last_name":"Cuervo","domain_name":"cepal","page_name":"MauricioCuervo","display_name":"Mauricio Cuervo","profile_url":"https://cepal.academia.edu/MauricioCuervo?f_ri=62112","photo":"https://0.academia-photos.com/9001556/2935598/3645046/s65_mauricio.cuervo.jpg"}</script></span></span></li><li class="js-paper-rank-work_37040032 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="37040032"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 37040032, container: ".js-paper-rank-work_37040032", }); });</script></li><li class="js-percentile-work_37040032 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 37040032; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_37040032"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_37040032 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="37040032"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 37040032; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=37040032]").text(description); $(".js-view-count-work_37040032").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_37040032").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="37040032"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">7</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="388" rel="nofollow" href="https://www.academia.edu/Documents/in/Latin_American_Studies">Latin American Studies</a>, <script data-card-contents-for-ri="388" type="text/json">{"id":388,"name":"Latin American Studies","url":"https://www.academia.edu/Documents/in/Latin_American_Studies?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6631" rel="nofollow" href="https://www.academia.edu/Documents/in/Economics_of_Innovation">Economics of Innovation</a>, <script data-card-contents-for-ri="6631" type="text/json">{"id":6631,"name":"Economics of Innovation","url":"https://www.academia.edu/Documents/in/Economics_of_Innovation?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="7739" rel="nofollow" href="https://www.academia.edu/Documents/in/Strategic_Planning">Strategic Planning</a>, <script data-card-contents-for-ri="7739" type="text/json">{"id":7739,"name":"Strategic Planning","url":"https://www.academia.edu/Documents/in/Strategic_Planning?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="9771" rel="nofollow" href="https://www.academia.edu/Documents/in/Foresight">Foresight</a><script data-card-contents-for-ri="9771" type="text/json">{"id":9771,"name":"Foresight","url":"https://www.academia.edu/Documents/in/Foresight?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=37040032]'), work: {"id":37040032,"title":"Prospectiva en América Latina. Aprendizajes a partir de la práctica. SEMINARIOS Y CONFERENCIAS No.88","created_at":"2018-07-13T08:29:13.060-07:00","url":"https://www.academia.edu/37040032/Prospectiva_en_Am%C3%A9rica_Latina_Aprendizajes_a_partir_de_la_pr%C3%A1ctica_SEMINARIOS_Y_CONFERENCIAS_No_88?f_ri=62112","dom_id":"work_37040032","summary":"Esta publicación es producto de la selección y edición de los mejores trabajos presentados durante las Terceras Jornadas de Planificación para el Desarrollo, que se celebraron en paralelo con el seminario internacional “Los Objetivos de Desarrollo Sostenible y la Construcción de Futuros para América Latina y el Caribe”, organizado en Santiago de Chile, del 18 al 20 de mayo de 2016, por el Instituto Latinoamericano y del Caribe de Planificación Económica y Social (ILPES) de la Comisión Económica para América Latina y el Caribe (CEPAL). Este seminario se desarrolló en el marco de las actividades del convenio de cooperación técnica entre la CEPAL y la República de Corea.","downloadable_attachments":[{"id":56990381,"asset_id":37040032,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":9001556,"first_name":"Mauricio","last_name":"Cuervo","domain_name":"cepal","page_name":"MauricioCuervo","display_name":"Mauricio Cuervo","profile_url":"https://cepal.academia.edu/MauricioCuervo?f_ri=62112","photo":"https://0.academia-photos.com/9001556/2935598/3645046/s65_mauricio.cuervo.jpg"}],"research_interests":[{"id":388,"name":"Latin American Studies","url":"https://www.academia.edu/Documents/in/Latin_American_Studies?f_ri=62112","nofollow":true},{"id":6631,"name":"Economics of Innovation","url":"https://www.academia.edu/Documents/in/Economics_of_Innovation?f_ri=62112","nofollow":true},{"id":7739,"name":"Strategic Planning","url":"https://www.academia.edu/Documents/in/Strategic_Planning?f_ri=62112","nofollow":true},{"id":9771,"name":"Foresight","url":"https://www.academia.edu/Documents/in/Foresight?f_ri=62112","nofollow":true},{"id":20436,"name":"Urban And Regional Planning","url":"https://www.academia.edu/Documents/in/Urban_And_Regional_Planning?f_ri=62112"},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112"},{"id":71006,"name":"Technology Foresight","url":"https://www.academia.edu/Documents/in/Technology_Foresight?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_17791733" data-work_id="17791733" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/17791733/The_effects_of_five_year_growth_hormone_replacement_therapy_on_muscle_strength_in_elderly_hypopituitary_patients">The effects of five-year growth hormone replacement therapy on muscle strength in elderly hypopituitary patients</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objective Little is known of the long-term effects of GH replacement therapy on muscle strength in elderly adults with adult onset GH deficiency (GHD). In this study, the effects of 5 years of GH replacement therapy on muscle function... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_17791733" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objective Little is known of the long-term effects of GH replacement therapy on muscle strength in elderly adults with adult onset GH deficiency (GHD). In this study, the effects of 5 years of GH replacement therapy on muscle function were determined in adults over 60 years of age with adult onset GHD. Design A prospective, open-label, single-centre study. Patients Twenty-six (12 male and 14 female) consecutive hypopituitary adults with adult onset GHD, mean age 65·0 (range 61-74) years. Measurements Upper leg muscle strength was measured using a Kin-Com dynamometer. Right and left handgrip strength were measured using an electronic grip force instrument.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/17791733" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="9c574571452c75a7e897e792ec0a6757" rel="nofollow" data-download="{"attachment_id":39713712,"asset_id":17791733,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/39713712/download_file?st=MTczOTgwMzc0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="37716122" href="https://independent.academia.edu/BengtakeBengtsson">Bengt-ake Bengtsson</a><script data-card-contents-for-user="37716122" type="text/json">{"id":37716122,"first_name":"Bengt-ake","last_name":"Bengtsson","domain_name":"independent","page_name":"BengtakeBengtsson","display_name":"Bengt-ake Bengtsson","profile_url":"https://independent.academia.edu/BengtakeBengtsson?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_17791733 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="17791733"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 17791733, container: ".js-paper-rank-work_17791733", }); 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$(".js-view-count[data-work-id=17791733]").text(description); $(".js-view-count-work_17791733").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_17791733").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="17791733"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">15</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="4228" rel="nofollow" href="https://www.academia.edu/Documents/in/Skeletal_muscle_biology">Skeletal muscle biology</a>, <script data-card-contents-for-ri="4228" type="text/json">{"id":4228,"name":"Skeletal muscle biology","url":"https://www.academia.edu/Documents/in/Skeletal_muscle_biology?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="12426" rel="nofollow" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a>, <script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="44530" rel="nofollow" href="https://www.academia.edu/Documents/in/Muscle_strength">Muscle strength</a>, <script data-card-contents-for-ri="44530" type="text/json">{"id":44530,"name":"Muscle strength","url":"https://www.academia.edu/Documents/in/Muscle_strength?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="52562" rel="nofollow" href="https://www.academia.edu/Documents/in/Growth_Hormone">Growth Hormone</a><script data-card-contents-for-ri="52562" type="text/json">{"id":52562,"name":"Growth Hormone","url":"https://www.academia.edu/Documents/in/Growth_Hormone?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=17791733]'), work: {"id":17791733,"title":"The effects of five-year growth hormone replacement therapy on muscle strength in elderly hypopituitary patients","created_at":"2015-11-05T06:16:33.265-08:00","url":"https://www.academia.edu/17791733/The_effects_of_five_year_growth_hormone_replacement_therapy_on_muscle_strength_in_elderly_hypopituitary_patients?f_ri=62112","dom_id":"work_17791733","summary":"Objective Little is known of the long-term effects of GH replacement therapy on muscle strength in elderly adults with adult onset GH deficiency (GHD). In this study, the effects of 5 years of GH replacement therapy on muscle function were determined in adults over 60 years of age with adult onset GHD. Design A prospective, open-label, single-centre study. Patients Twenty-six (12 male and 14 female) consecutive hypopituitary adults with adult onset GHD, mean age 65·0 (range 61-74) years. Measurements Upper leg muscle strength was measured using a Kin-Com dynamometer. Right and left handgrip strength were measured using an electronic grip force instrument.","downloadable_attachments":[{"id":39713712,"asset_id":17791733,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":37716122,"first_name":"Bengt-ake","last_name":"Bengtsson","domain_name":"independent","page_name":"BengtakeBengtsson","display_name":"Bengt-ake Bengtsson","profile_url":"https://independent.academia.edu/BengtakeBengtsson?f_ri=62112","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":4228,"name":"Skeletal muscle biology","url":"https://www.academia.edu/Documents/in/Skeletal_muscle_biology?f_ri=62112","nofollow":true},{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=62112","nofollow":true},{"id":44530,"name":"Muscle strength","url":"https://www.academia.edu/Documents/in/Muscle_strength?f_ri=62112","nofollow":true},{"id":52562,"name":"Growth Hormone","url":"https://www.academia.edu/Documents/in/Growth_Hormone?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112"},{"id":100336,"name":"Body Composition","url":"https://www.academia.edu/Documents/in/Body_Composition?f_ri=62112"},{"id":208591,"name":"Hypopituitarism","url":"https://www.academia.edu/Documents/in/Hypopituitarism?f_ri=62112"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=62112"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=62112"},{"id":413194,"name":"Analysis of Variance","url":"https://www.academia.edu/Documents/in/Analysis_of_Variance?f_ri=62112"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=62112"},{"id":556021,"name":"Muscle contraction","url":"https://www.academia.edu/Documents/in/Muscle_contraction?f_ri=62112"},{"id":923234,"name":"Clinical Endocrinology","url":"https://www.academia.edu/Documents/in/Clinical_Endocrinology?f_ri=62112"},{"id":973999,"name":"Tensile Strength","url":"https://www.academia.edu/Documents/in/Tensile_Strength?f_ri=62112"},{"id":1145265,"name":"Knee Joint","url":"https://www.academia.edu/Documents/in/Knee_Joint?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_30731061" data-work_id="30731061" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/30731061/Limited_effects_of_growth_hormone_replacement_in_adults_with_growth_hormone_deficiency_after_treatment_for_acromegaly">Limited effects of growth hormone replacement in adults with growth hormone deficiency after treatment for acromegaly</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The aim of this study was to assess the effects of replacement with recombinant human growth hormone (rhGH) in patients with GH deficiency (GHD) after treatment of acromegaly. Intervention study. Sixteen patients (8 men, age 56 years),... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_30731061" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The aim of this study was to assess the effects of replacement with recombinant human growth hormone (rhGH) in patients with GH deficiency (GHD) after treatment of acromegaly. Intervention study. Sixteen patients (8 men, age 56 years), treated for acromegaly by surgery and radiotherapy, with an insufficient GH response to insulininduced hypoglycaemia, were treated with 1 year of rhGH replacement. Study parameters were assessed at baseline and after 1 year of rhGH replacement. Study parameters were cardiac function, body composition, bone mineral density (BMD), fasting lipids, glucose, bone turnover markers, and Quality of Life (QoL). During rhGH replacement IGF-I concentrations increased from -0.4 ± 0.7 to 1.0 ± 1.5 SD (P = 0.001), with a mean daily dose of 0.2 ± 0.1 mg in men and 0.3 ± 0.2 mg in women. Nonetheless, rhGH replacement did not alter cardiac function, lipid and glucose concentrations, body composition or QoL. Bone turnover markers (PINP and b crosslaps) levels increased (P = 0.005 and P = 0.021, respectively), paralleled by a small, but significant decrease in BMD of the hip. The beneficial effects of rhGH replacement in patients with GHD during cure from acromegaly are limited in this study.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/30731061" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a782a3acccbe1005648be6d0e75824e7" rel="nofollow" data-download="{"attachment_id":51178701,"asset_id":30731061,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/51178701/download_file?st=MTczOTgwMzc0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="58403059" href="https://independent.academia.edu/FerdinandRoelfsema">Ferdinand Roelfsema</a><script data-card-contents-for-user="58403059" type="text/json">{"id":58403059,"first_name":"Ferdinand","last_name":"Roelfsema","domain_name":"independent","page_name":"FerdinandRoelfsema","display_name":"Ferdinand Roelfsema","profile_url":"https://independent.academia.edu/FerdinandRoelfsema?f_ri=62112","photo":"https://0.academia-photos.com/58403059/49115808/37085760/s65_ferdinand.roelfsema.png"}</script></span></span></li><li class="js-paper-rank-work_30731061 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="30731061"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 30731061, container: ".js-paper-rank-work_30731061", }); 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$(".js-view-count[data-work-id=30731061]").text(description); $(".js-view-count-work_30731061").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_30731061").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="30731061"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">15</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="7470" rel="nofollow" href="https://www.academia.edu/Documents/in/Quality_of_life">Quality of life</a>, <script data-card-contents-for-ri="7470" type="text/json">{"id":7470,"name":"Quality of life","url":"https://www.academia.edu/Documents/in/Quality_of_life?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="12426" rel="nofollow" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a>, <script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a>, <script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="69565" rel="nofollow" href="https://www.academia.edu/Documents/in/Human_Growth_Hormone">Human Growth Hormone</a><script data-card-contents-for-ri="69565" type="text/json">{"id":69565,"name":"Human Growth Hormone","url":"https://www.academia.edu/Documents/in/Human_Growth_Hormone?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=30731061]'), work: {"id":30731061,"title":"Limited effects of growth hormone replacement in adults with growth hormone deficiency after treatment for acromegaly","created_at":"2017-01-04T04:02:48.092-08:00","url":"https://www.academia.edu/30731061/Limited_effects_of_growth_hormone_replacement_in_adults_with_growth_hormone_deficiency_after_treatment_for_acromegaly?f_ri=62112","dom_id":"work_30731061","summary":"The aim of this study was to assess the effects of replacement with recombinant human growth hormone (rhGH) in patients with GH deficiency (GHD) after treatment of acromegaly. Intervention study. Sixteen patients (8 men, age 56 years), treated for acromegaly by surgery and radiotherapy, with an insufficient GH response to insulininduced hypoglycaemia, were treated with 1 year of rhGH replacement. Study parameters were assessed at baseline and after 1 year of rhGH replacement. Study parameters were cardiac function, body composition, bone mineral density (BMD), fasting lipids, glucose, bone turnover markers, and Quality of Life (QoL). During rhGH replacement IGF-I concentrations increased from -0.4 ± 0.7 to 1.0 ± 1.5 SD (P = 0.001), with a mean daily dose of 0.2 ± 0.1 mg in men and 0.3 ± 0.2 mg in women. Nonetheless, rhGH replacement did not alter cardiac function, lipid and glucose concentrations, body composition or QoL. Bone turnover markers (PINP and b crosslaps) levels increased (P = 0.005 and P = 0.021, respectively), paralleled by a small, but significant decrease in BMD of the hip. The beneficial effects of rhGH replacement in patients with GHD during cure from acromegaly are limited in this study.","downloadable_attachments":[{"id":51178701,"asset_id":30731061,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":58403059,"first_name":"Ferdinand","last_name":"Roelfsema","domain_name":"independent","page_name":"FerdinandRoelfsema","display_name":"Ferdinand Roelfsema","profile_url":"https://independent.academia.edu/FerdinandRoelfsema?f_ri=62112","photo":"https://0.academia-photos.com/58403059/49115808/37085760/s65_ferdinand.roelfsema.png"}],"research_interests":[{"id":7470,"name":"Quality of life","url":"https://www.academia.edu/Documents/in/Quality_of_life?f_ri=62112","nofollow":true},{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=62112","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=62112","nofollow":true},{"id":69565,"name":"Human Growth Hormone","url":"https://www.academia.edu/Documents/in/Human_Growth_Hormone?f_ri=62112","nofollow":true},{"id":71289,"name":"Glucose","url":"https://www.academia.edu/Documents/in/Glucose?f_ri=62112"},{"id":100336,"name":"Body Composition","url":"https://www.academia.edu/Documents/in/Body_Composition?f_ri=62112"},{"id":131495,"name":"Heart","url":"https://www.academia.edu/Documents/in/Heart?f_ri=62112"},{"id":139532,"name":"Bone Density","url":"https://www.academia.edu/Documents/in/Bone_Density?f_ri=62112"},{"id":184609,"name":"Lipid metabolism","url":"https://www.academia.edu/Documents/in/Lipid_metabolism?f_ri=62112"},{"id":208591,"name":"Hypopituitarism","url":"https://www.academia.edu/Documents/in/Hypopituitarism?f_ri=62112"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=62112"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=62112"},{"id":656285,"name":"Acromegaly","url":"https://www.academia.edu/Documents/in/Acromegaly?f_ri=62112"},{"id":963794,"name":"Pituitary","url":"https://www.academia.edu/Documents/in/Pituitary?f_ri=62112"},{"id":1621167,"name":"Hormone Replacement Therapy","url":"https://www.academia.edu/Documents/in/Hormone_Replacement_Therapy?f_ri=62112"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_19276177" data-work_id="19276177" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/19276177/Comparison_of_Continuation_or_Cessation_of_Growth_Hormone_GH_Therapy_on_Body_Composition_and_Metabolic_Status_in_Adolescents_with_Severe_GH_Deficiency_at_Completion_of_Linear_Growth">Comparison of Continuation or Cessation of Growth Hormone (GH) Therapy on Body Composition and Metabolic Status in Adolescents with Severe GH Deficiency at Completion of Linear Growth</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Although GH replacement improves the features of GH deficiency (GHD) in adults, it has yet to be established whether cessation of GH at completion of childhood growth results in adverse consequences for the adolescent with GHD. Effects of... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_19276177" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Although GH replacement improves the features of GH deficiency (GHD) in adults, it has yet to be established whether cessation of GH at completion of childhood growth results in adverse consequences for the adolescent with GHD. Effects of continuation or cessation of GH on body composition, insulin sensitivity, and lipid levels were studied in 24 adolescents (13 males, 11 females, aged 17.0 ؎ 0.3, yr, mean ؎ SE, puberty stage 4 or 5) in whom height velocity was less than 2 cm/yr. Provocative testing confirmed severe GHD [peak GH < 9 mU/liter (3 g/liter)] in all cases and was followed by a lead-in period of 3 months during which the pediatric dose of GH continued unchanged. Baseline investigations were then performed using dual-energy x-ray absorptiometry (body composition), lipid measurements, and assessment of insulin sensitivity by both homeostasis model assessment and a short insulin tolerance test. Twelve patients remained on GH (0.35 U/kg⅐wk), and 12 patients ceased GH treatment. The groups were followed up in parallel with repeat observations made after 6 and 12 months.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/19276177" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="d8ff4ff5d6414ff8a2c2e48832c89ef9" rel="nofollow" data-download="{"attachment_id":40530650,"asset_id":19276177,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/40530650/download_file?st=MTczOTgwMzc0Niw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="39406904" href="https://independent.academia.edu/JohnMonson">John Monson</a><script data-card-contents-for-user="39406904" type="text/json">{"id":39406904,"first_name":"John","last_name":"Monson","domain_name":"independent","page_name":"JohnMonson","display_name":"John Monson","profile_url":"https://independent.academia.edu/JohnMonson?f_ri=62112","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_19276177 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="19276177"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 19276177, container: ".js-paper-rank-work_19276177", }); 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$(".js-view-count[data-work-id=19276177]").text(description); $(".js-view-count-work_19276177").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_19276177").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="19276177"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">11</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="51373" rel="nofollow" href="https://www.academia.edu/Documents/in/Insulin_Resistance">Insulin Resistance</a>, <script data-card-contents-for-ri="51373" type="text/json">{"id":51373,"name":"Insulin Resistance","url":"https://www.academia.edu/Documents/in/Insulin_Resistance?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="52055" rel="nofollow" href="https://www.academia.edu/Documents/in/Lipids">Lipids</a>, <script data-card-contents-for-ri="52055" type="text/json">{"id":52055,"name":"Lipids","url":"https://www.academia.edu/Documents/in/Lipids?f_ri=62112","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="52562" rel="nofollow" href="https://www.academia.edu/Documents/in/Growth_Hormone">Growth Hormone</a><script data-card-contents-for-ri="52562" type="text/json">{"id":52562,"name":"Growth Hormone","url":"https://www.academia.edu/Documents/in/Growth_Hormone?f_ri=62112","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=19276177]'), work: {"id":19276177,"title":"Comparison of Continuation or Cessation of Growth Hormone (GH) Therapy on Body Composition and Metabolic Status in Adolescents with Severe GH Deficiency at Completion of Linear Growth","created_at":"2015-12-01T01:26:56.668-08:00","url":"https://www.academia.edu/19276177/Comparison_of_Continuation_or_Cessation_of_Growth_Hormone_GH_Therapy_on_Body_Composition_and_Metabolic_Status_in_Adolescents_with_Severe_GH_Deficiency_at_Completion_of_Linear_Growth?f_ri=62112","dom_id":"work_19276177","summary":"Although GH replacement improves the features of GH deficiency (GHD) in adults, it has yet to be established whether cessation of GH at completion of childhood growth results in adverse consequences for the adolescent with GHD. Effects of continuation or cessation of GH on body composition, insulin sensitivity, and lipid levels were studied in 24 adolescents (13 males, 11 females, aged 17.0 ؎ 0.3, yr, mean ؎ SE, puberty stage 4 or 5) in whom height velocity was less than 2 cm/yr. Provocative testing confirmed severe GHD [peak GH \u003c 9 mU/liter (3 g/liter)] in all cases and was followed by a lead-in period of 3 months during which the pediatric dose of GH continued unchanged. Baseline investigations were then performed using dual-energy x-ray absorptiometry (body composition), lipid measurements, and assessment of insulin sensitivity by both homeostasis model assessment and a short insulin tolerance test. Twelve patients remained on GH (0.35 U/kg⅐wk), and 12 patients ceased GH treatment. 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