알테오젠 SC제형 변경기술…특허 침해의 소지 전혀 없다

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$('.hk-top__search .btn-search').hide(); $('.hk-top__search .hk-top__search__layer').removeClass('auto'); }); }); </script>   <div class="item hk-top__user">  <button type="button" class="btn-hk-user before-login" style="display: none;"> 로그인 </button>  <button type="button" class="btn-hk-user after-login" style="display: none;"> <span class="blind">회원 메뉴</span> </button> <div class="hk-user__layer"> <div class="layer-inner">  <div class="hk-user__info before" style="display: none;"> <div class="hk-user__btns"> <a href="https://member.hankyung.com/apps.frame/sso.join" class="btn-join return-url" rel="nofollow"> <span class="txt">회원가입</span> </a> <a href="https://member.hankyung.com/apps.frame/login" class="btn-login return-url" rel="nofollow"> <span class="txt">로그인</span> </a> </div> <div class="info__panel"> <div class="info-item info-msg"> <p><strong>한국경제 회원이 되어 보세요</strong></p> <p>지금 바로 한국경제 회원으로 가입하시고, 독점 혜택을 누려보세요</p> </div> <ul class="info-item member-benefit"> <li>특별한 뉴스와 분석 보고서 접근</li> <li>주식 시장 및 경제 동향에 대한 최신 정보</li> <li>한경만의 독자적인 콘텐츠에 대한 접근</li> <li>이벤트 및 세미나 참가 기회</li> </ul> <p class="info-item txt"> 이미 회원이시면 <strong><a href="https://member.hankyung.com/apps.frame/login" class="return-url">로그인</a></strong>을 클릭해 주세요 </p> </div> <div class="hk-user__links"> <div class="item"> <a href="https://www.hankyung.com/help" class="item" rel="nofollow">고객센터</a> </div> </div> </div>  <div class="hk-user__info after" style="display: none;"> <div class="info__mypages"> <div class="my-item my-item-account"> <a href="https://member.hankyung.com/apps.frame/member.main" class="my-item__link return-url"> <div class="my-item__icon account-email-icon"></div> <div class="my-item__txt"> <p class="tit account-email"></p> <p class="desc">계정관리</p> </div> </a> </div>  <div class="my-item my-item-myhankyung"> <a href="https://www.hankyung.com/myhankyung" class="my-item__link"> <div class="my-item__txt"> <p class="tit">My한경</p> <p class="desc">기자 구독, 스크랩, 증권</p> </div> </a> </div> <p class="info-txt">한경 AI! 당신의 취향과 관심사를 분석하여 꼭 맞는 뉴스를 선별해드립니다.</p>  <div class="my-item my-item-subscribe"> <a href="https://www.hankyung.com/pay" class="my-item__link"> <div class="my-item__txt"> <p class="tit">구독</p> <p class="desc">유료 상품</p> </div> </a> </div> </div> <div class="hk-user__links"> <div class="item"> <a href="https://member.hankyung.com/apps.frame/login.work.logout" class="return-url">로그아웃</a> </div> <div class="item"> <a href="https://www.hankyung.com/help" class="item" rel="nofollow">고객센터</a> </div> </div> </div> </div> <button type="button" class="btn-close-layer"> <span class="blind">회원 메뉴 닫기</span> </button> </div> </div> <script> // 로그인 여부 체크 function signInCheck(){ // 운영/개발서버 회원 도메인(member) 분기 let is_stg = false; if(location.host != location.host.replace("stg-", "") ){ is_stg = true; } const url = escape(document.location.href); $('.hk-top__user .hk-user__info a.return-url').each(function(index,element){ let member_url = $(element).attr('href'); if(is_stg == true){ member_url = member_url.replace("https://member.hankyung.com", "https://stg-member.hankyung.com"); } $(element).attr('href', member_url+'?url='+url); }); const user_id = $.cookie('UserId'); const tokenCookie = $.cookie('ssoToken'); if(!tokenCookie){ $('.hk-top__user .btn-hk-user.before-login').show(); $('.hk-top__user .hk-user__info.before').show(); $('.hk-top__user .btn-hk-user.after-login').remove(); $('.hk-top__user .hk-user__info.after').remove(); return false; } let checkFlag = true; if( $.cookie('ssoTokenCheckTime') && user_id){ const checkTime = $.cookie('ssoTokenCheckTime'); const today = new Date().toISOString().substring(0,10); if( checkTime == today ) checkFlag = false; } if(!checkFlag){ setSingInfo({result_code:'0000'}); return false; } // 2024.09.26 운영/stg 토큰 구분 추가 tokenUrl = "https://member.hankyung.com/apps.frame/sso.check.token"; if(is_stg == true){ tokenUrl = "https://stg-member.hankyung.com/apps.frame/sso.check.token" } $.ajax({ type : "POST", url : tokenUrl, crossDomain: true, dataType: 'jsonp', jsonp: 'jsonp_callback', data : {'token' : tokenCookie, 'key' : "a8bdf898783883b64503b8915deeb57767f935a24daf44150723299c01c8898a", 'fn' : "setSingInfo" } }); } function setSingInfo(result){ if(result.result_code != "0000"){ $('.hk-top__user .btn-hk-user.before-login').show(); $('.hk-top__user .hk-user__info.before').show(); $('.hk-top__user .btn-hk-user.after-login').remove(); $('.hk-top__user .hk-user__info.after').remove(); return false; } $('.hk-top__user .btn-hk-user.before-login').remove(); $('.hk-top__user .hk-user__info.before').remove(); // 브라우저 종료시 만료되는 쿠키를 셋팅한다. $.cookie('ssoTokenCheckTime', new Date().toISOString().substring(0,10), { expires: null, path: '/', domain: 'hankyung.com'}); // 이름대신 통합회원ID 입력 let iconLoginType = 'icon-mylogin-email'; if($.cookie("login_type")){ iconLoginType = 'icon-mylogin-'+$.cookie("login_type"); } const textLoingTypes = { 'icon-mylogin-email':'한경으로 로그인', 'icon-mylogin-kakao':'카카오로 로그인', 'icon-mylogin-naver':'네이버로 로그인', 'icon-mylogin-google':'구글로 로그인', 'icon-mylogin-apple':'애플로 로그인' } const textLoingType = textLoingTypes[iconLoginType]; $('.hk-top__user .hk-user__info.after .my-item-account .my-item__icon').html('<span class="'+iconLoginType+'"><span class="blind">'+textLoingType+'</span></span>'); $('.hk-top__user .hk-user__info.after .my-item-account .my-item__txt .account-email').text($.cookie("SSOid")); $('.hk-top__user .btn-hk-user.after-login').show(); $('.hk-top__user .hk-user__info.after').show(); } $(document).ready(function(){ signInCheck(); // 회원 레이어 열고/닫기 $('.btn-hk-user').on("click", function() { $('.hk-top__user').toggleClass('active'); }); $('.hk-user__layer .btn-close-layer').on("click", function() { $('.hk-top__user').removeClass('active'); }); // 레이어닫기 $(document).on('mouseup',function(e){ if (!$(e.target).hasClass('hk-user__layer') && !$(e.target).parents().hasClass('hk-user__layer')) { $('.hk-top__user').removeClass('active'); }; }); }); </script>  </div> </div> </div> <div class="promotion-nav-wrap"> <div class="promotion-nav"></div> <div class="promotion-nav-all"><ul></ul></div> </div> <script> if($.fn.slick == undefined){ $('head').append('<link rel="stylesheet" href="https://hkstatic.hankyung.com/resource/common/library/slick/v1.8.1/slick.css">'); slickScript = document.createElement('script'); slickScript.src = "https://hkstatic.hankyung.com/resource/common/library/slick/v1.8.1/slick.min.js"; document.head.appendChild(slickScript); } function setSectionNavigationPostion(){ let path = document.location.pathname; if(path != '/' && path.lastIndexOf('/') == path.length -1){ path = path.slice(0, -1); } let menuarray = path.split("/"); menuarray.shift(); if(menuarray.length == 1 && !path.includes('all-news')){ return false; } // console.log(path); $('.section__nav .section__gnb > li > a').each(function(index, element){ // 2024.11.07 url에 상대경로 있는 경우 const url = new URL($(element).attr('href'), location.origin); let linkpath = url.pathname; if(linkpath.lastIndexOf('/') == linkpath.length -1){ linkpath = linkpath.slice(0, -1); } if(path == linkpath){ $(element).closest('li').addClass('on'); return false; } }); $('.section__nav .section__gnb .nav-dropdown__menu a').each(function(index, element){ // 2024.11.07 url에 상대경로 있는 경우 const url = new URL($(element).attr('href'), location.origin); let linkpath = url.pathname; if(linkpath.lastIndexOf('/') == linkpath.length -1){ linkpath = linkpath.slice(0, -1); } if(path == linkpath){ $(element).closest('li.nav-dropdown').addClass('on'); return false; } }); } $(function () { let is_stg = false; if(location.host != location.host.replace("stg-", "") ){ is_stg = true; } // 2024.07.30 스크롤이 0일때는 버튼 미노출, 스크롤이 0보다 크면 버튼 노출되도록 수정 by yongt // $(window).scroll(function(){ // if($(this).scrollTop() > 0){ // $("html").addClass("isSticky"); // }else{ // $('html').removeClass('isSticky'); // } // }); // 2024.10.07 hk-header 높이에 따라 html sticky class 적용되도록 수정 by yongt // Sticky header let headerTop = $('.hk-header').offset().top; let headerH = $('.hk-header').outerHeight(); // 초기 .hk-header 높이 세팅(fixed 후 스크롤 움직임 방지) $('.hk-header').css('height',headerH); // 스크롤이 헤더 영역을 지나면 html태그에 .isSticky 토글 $(window).scroll(function() { let winScr = $(this).scrollTop(); if (winScr > headerTop + headerH) { $('html').addClass('isSticky'); } else { $('html').removeClass('isSticky'); } }); setSectionNavigationPostion(); // 프로모션 정보 호출 let promotionUrl = 'https://www.hankyung.com/ext-api/promotion'; if(is_stg == true){ promotionUrl = 'https://stg-www.hankyung.com/ext-api/promotion'; } $.get(promotionUrl, function(data, status){ if(data.length == 0){ $('.promotion-nav-wrap').remove(); return; } $.each(data, function(idx, val){ $(".promotion-nav-wrap .promotion-nav").append('\ <div class="item">\ <a href="'+val.link+'" '+(val.isblank == 'Y' ? 'target="_blank" rel="nofollow"' : '')+'>'+val.title+'</a>\ </div>\ '); $(".promotion-nav-wrap .promotion-nav-all ul").append('\ <li>\ <a href="'+val.link+'" '+(val.isblank == 'Y' ? 'target="_blank" rel="nofollow"' : '')+'>'+val.title+'</a>\ </li>\ '); }); $('.promotion-nav a, .promotion-nav-all').on({ mouseenter: function () { $('.promotion-nav-all').addClass('on'); }, mouseleave: function () { $('.promotion-nav-all').removeClass('on'); } }); $('.promotion-nav').slick({ vertical: true, verticalSwiping: true, arrows: false, dots: false, autoplay: true, speed: 300, pauseOnHover: false, }); }); // gnb 메뉴 활성화 blur 처리 $('.nav-dropdown[data-event="hover"]').on('mouseout',function(){ $(this).find('.nav-dropdown__toggle, .nav-link').blur(); }); // 2024.10.31 프로모션 배너 정보 호출 추가 let gnb_banner_url = "https://www.hankyung.com/ext-api/gnb-banner"; if(is_stg == true){ gnb_banner_url = "https://stg-www.hankyung.com/ext-api/gnb-banner"; } $.get(gnb_banner_url, (data) => { if(data){ $(".banner-box").append(` <a href="${data.URL}" ${data.IS_OUTER == 'Y' ? 'target="_blank"' : ''}> <img src="${data.IMG2_URL}" alt="${data.ALT}"> </a> `); }else{ $(".banner-box").remove(); } }); }); </script> <div class="section__gnb__wrap"> <div class="section__logo__area"> <h1 class="section__logo"> <a href="https://www.hankyung.com/bioinsight" class="section__title logo__bioinsight"> <span class="blind">BIO Insight</span> </a> </h1> </div> </div> <div class="scroll-indicator"> <div></div> </div> </div> </header> <div class="ad-top ad_area" style="height: 250px;"></div>  <div id="container"> <div class="article-wrap"> <div class="article-container v2"> <article class="article-contents"> <h1 class="headline"> 알테오젠 "SC제형 변경기술…특허 침해의 소지 전혀 없다" </h1> <div class="content "> <div class="article"> <div class="article-byline-wrap"> <div class="author-container login_need">  <div class="author-list"> <div class="author link subs_author_list" data-email="youforest@hankyung.com" data-name="김유림 기자"> <a href="https://www.hankyung.com/reporter/3601" class="item">김유림 기자</a> <button type="button" class="btn-star-toggle" onclick="clickMyReporter('youforest@hankyung.com', this)"> <svg x="0" y="0" width="15" height="15" viewBox="0 0 21.35 20.45"> <path class="svg-star-fill" d="M4.96,20.45c-0.29,0-0.59-0.09-0.84-0.27c-0.44-0.32-0.66-0.86-0.57-1.4l0.97-5.66L0.43,9.17 C0.04,8.79-0.1,8.23,0.07,7.71c0.17-0.52,0.61-0.89,1.15-0.97l5.68-0.83L9.4,0.8C9.64,0.31,10.13,0,10.68,0 c0.51,0,1.04,0.31,1.28,0.8l2.54,5.15l5.63,0.79c0.54,0.08,0.98,0.45,1.15,0.97c0.17,0.52,0.03,1.08-0.36,1.46l-4.11,4.01l0.99,5.6 c0.09,0.54-0.13,1.08-0.57,1.4c-0.44,0.32-1.02,0.36-1.5,0.11l-5.08-2.67l-5.02,2.67C5.42,20.39,5.19,20.45,4.96,20.45z" fill="#ddd"></path> <path class="svg-star" d="M4.96,20.45c-0.29,0-0.59-0.09-0.84-0.27c-0.44-0.32-0.66-0.86-0.57-1.4l0.97-5.66L0.43,9.17 C0.04,8.79-0.1,8.23,0.07,7.71c0.17-0.52,0.61-0.89,1.15-0.97l5.68-0.83L9.4,0.8C9.64,0.31,10.13,0,10.68,0 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ALT-B4는 정맥주사 의약품을 피하주사 제형으로 바꿔주는 알테오젠의 플랫폼 기술이다. 알테오젠은 2020년 6월 미국 머크(MSD), 이달 초 일본 다이이찌산쿄와 ALT-B4 플랫폼 기술수출 계약을 맺었다.<br /><br />전 부사장은 “MSD, 다이이찌산쿄 등과 기술이전 계약을 맺기 전에 ALT-B4의 특허 문제를 다각적으로 검토해 문제가 없다는 확인을 받았다”고 설명했다.<br /><br />알테오젠의 특허 침해 논란은 미국 골드만삭스가 지난 19일 MSD의 면역항암제 키트루다에 사용된 ALT-B4가 할로자임의 엠다제(MDASE) 특허를 침해했을 가능성을 제기하면서 불거졌다. 알테오젠과 할로자임은 히알루로니다제 효소를 활용해 정맥주사를 피하주사로 바꿔주는 제형 변경 기술을 보유하고 있다. 할로자임 특허는 당초 미국에서 2027년 만료될 예정이었지만 효소를 변경하는 방식인 엠다제로 특허 기간을 2034년까지 늘렸다.<br /><br />전 부사장은 “미국의 유명 특허 소송 로펌 세 곳에서 특허 분석을 거친 결과 문제가 없다는 의견을 받았다”고 말했다. 알테오젠 ALT-B4의 미국 특허 만료 시기는 2043년이다.<br /><br />알테오젠은 MSD와 맺은 기존 계약이 견고하다고 강조했다. 전 부사장은 “MSD가 할로자임의 기술로 키트루다 피하주사 제형을 상용화하기 위해서는 처음부터 다시 개발해야 한다”며 “2028년 키트루다 정맥주사 제형 특허가 만료되는 걸 감안하면 MSD가 다른 선택을 하기 어렵다”고 했다. MSD는 지난해 매출 35조원을 올린 세계 1위 항암제 키트루다의 특허 절벽을 피하기 위해 키트루다 피하주사 제형을 개발 중이다.<br /><br />MSD는 12일 미국 특허청에 할로자임 엠다제의 특허 무효심판 청구를 제기했다. 특허 적용 대상이 광범위하고 불투명하다는 이유에서다.<br /><br />특허 침해 논란에 이날 알테오젠 주가는 29만2000원으로 전날 대비 15.73% 급락했다.<br /><br />김유림 기자 youforest@hankyung.com </div> </div> <div class="empathy-wrap not_personal_service"> <button type="button" class="btn-like" data-kind="1" data-reaction="good" onclick="clickReaction('2024112293071', 1, this)"> <svg x="0" y="0" width="26" height="28" viewBox="0 0 25.3 25.5"> <path class="svg-icon" d="M24.7,11c-1-1.4-2.9-1.4-3.2-1.4h-4.9c-0.1,0-0.2-0.1-0.2-0.1c0-0.1-0.1-0.2,0-0.3c0.4-0.6,0.6-1.1,0.8-1.4 c0.5-1,2-4.4-0.3-6.7c-1-1-2.2-1.3-3.4-1c-0.8,0.2-1.4,0.7-1.9,1.4L6,9.6H1c-0.6,0-1,0.5-1,1v13.8c0,0.6,0.5,1,1,1h5.5h10.4 c0.7,0,1.3-0.1,2-0.4c1.3-0.5,2.3-1.5,2.9-2.8l0-0.1c0.7-1.5,2.3-4.9,3.1-7.2C25.5,13.4,25.4,12,24.7,11z M2.1,11.7h3.4v11.7H2.1 V11.7z M23,14.3c-0.7,2.1-2.3,5.5-3,7l0,0.1c-0.4,0.8-1,1.5-1.8,1.8c-0.4,0.2-0.9,0.3-1.3,0.3H7.5V11l5.7-8.3 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