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class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17375430/Preliminary_phytochemical_and_pharmacological_screening_of_Murraya_exotica_Linn_leaves_extract"><img alt="Research paper thumbnail of Preliminary phytochemical and pharmacological screening of Murraya exotica Linn. leaves extract" class="work-thumbnail" src="https://attachments.academia-assets.com/39474154/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17375430/Preliminary_phytochemical_and_pharmacological_screening_of_Murraya_exotica_Linn_leaves_extract">Preliminary phytochemical and pharmacological screening of Murraya exotica Linn. leaves extract</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://manarat.academia.edu/AminaKhatun">Amina Khatun</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://manarat.academia.edu/shamimajahan">shamima jahan</a></span></div><div class="wp-workCard_item"><span>Oriental Pharmacy and Experimental Medicine</span><span>, 2014</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="a693e36c5af91cc39ccbe58479a5e451" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":39474154,"asset_id":17375430,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/39474154/download_file?st=MTczMjcxODYyOSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="17289442"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/17289442/Khatun_Murraya"><img alt="Research paper thumbnail of Khatun Murraya" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/17289442/Khatun_Murraya">Khatun Murraya</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://manarat.academia.edu/shamimajahan">shamima jahan</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://manarat.academia.edu/AminaKhatun">Amina Khatun</a></span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="a8ca6be207a9c961afc44391160b97cf" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":39418363,"asset_id":17289442,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/39418363/download_file?st=MTczMjcxODYyOSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="17289442"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="17289442"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17289442; 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(Family: Rutaceae) was evaluated for possible cytotoxic, thrombolytic and antioxidant activities in this study. The extract was tested for phytochemical group test by standard method using chromogenic reagents, in vivo brine shrimp lethality assay using Artemia salina, thrombolytic effect by using the standard streptokinase and antioxidant activity by using 2,2-diphenyl-1-picryl-hydrazyl (DPPH). The study revealed the presence of reducing sugars, tannins, saponins and alkaloids. The extract showed statistically significant (p\u003c0.01) potent cytotoxic effect in brine shrimp lethality bioassay where the value of LC 50 and LC 90 were 1.27 μg/ml and 5.09 μg/ml respectively compared with the standard vincristine sulphate with the value of LC 50 and LC 90 0.09 μg/ml and 4.83 μg/ml respectively after 24 h. The study gave a significant indication to the use of the plant extract as a potential source for cytotoxic compounds. The extract showed mild thrombolytic effect of 15.78 % thrombolytic activity whereas the standard streptokinase showed 76.50±0.82 %. In the antioxidant activity study, the extract showed free radical scavenging activity where IC 50 = 1.25 μg/ml and IC 90 = 4.4 μg/ml, compared with the standard ascorbic acid showing IC 50 =0.01 μg/ml and IC 90 =3.58 μg/ml. Based on the findings of phytochemical, toxicological and anti-oxidative activity, it is evident that the plant may contain some novel compounds that possess potent anti-mutagenic and anti-oxidative activities. 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(Family: Rutaceae) was evaluated for possible cytotoxic, thrombolytic and antioxidant activities in this study. The extract was tested for phytochemical group test by standard method using chromogenic reagents, in vivo brine shrimp lethality assay using Artemia salina, thrombolytic effect by using the standard streptokinase and antioxidant activity by using 2,2-diphenyl-1-picryl-hydrazyl (DPPH). The study revealed the presence of reducing sugars, tannins, saponins and alkaloids. The extract showed statistically significant (p\u003c0.01) potent cytotoxic effect in brine shrimp lethality bioassay where the value of LC 50 and LC 90 were 1.27 μg/ml and 5.09 μg/ml respectively compared with the standard vincristine sulphate with the value of LC 50 and LC 90 0.09 μg/ml and 4.83 μg/ml respectively after 24 h. The study gave a significant indication to the use of the plant extract as a potential source for cytotoxic compounds. The extract showed mild thrombolytic effect of 15.78 % thrombolytic activity whereas the standard streptokinase showed 76.50±0.82 %. In the antioxidant activity study, the extract showed free radical scavenging activity where IC 50 = 1.25 μg/ml and IC 90 = 4.4 μg/ml, compared with the standard ascorbic acid showing IC 50 =0.01 μg/ml and IC 90 =3.58 μg/ml. Based on the findings of phytochemical, toxicological and anti-oxidative activity, it is evident that the plant may contain some novel compounds that possess potent anti-mutagenic and anti-oxidative activities. 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