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Dit is echter niet verplicht." class=""><span>Account aanmaken</span></a> </li> <li id="pt-login-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=Speciaal:Aanmelden&returnto=Bloedplaatje" title="U wordt van harte uitgenodigd om aan te melden, maar dit is niet verplicht [o]" accesskey="o" class=""><span>Aanmelden</span></a> </li> </ul> </div> </div> </div> <div id="vector-user-links-dropdown" class="vector-dropdown vector-user-menu vector-button-flush-right vector-user-menu-logged-out" title="Meer opties" > <input type="checkbox" id="vector-user-links-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-user-links-dropdown" class="vector-dropdown-checkbox " aria-label="Persoonlijke hulpmiddelen" > <label id="vector-user-links-dropdown-label" for="vector-user-links-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-ellipsis mw-ui-icon-wikimedia-ellipsis"></span> <span class="vector-dropdown-label-text">Persoonlijke hulpmiddelen</span> </label> <div class="vector-dropdown-content"> <div id="p-personal" class="vector-menu mw-portlet mw-portlet-personal user-links-collapsible-item" title="Gebruikersmenu" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-sitesupport" class="user-links-collapsible-item mw-list-item"><a href="//donate.wikimedia.org/wiki/Special:FundraiserRedirector?utm_source=donate&utm_medium=sidebar&utm_campaign=C13_nl.wikipedia.org&uselang=nl"><span>Doneren</span></a></li><li id="pt-createaccount" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Speciaal:GebruikerAanmaken&returnto=Bloedplaatje" title="Registreer u vooral en meld u aan. 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class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">Inhoud</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">naar zijbalk verplaatsen</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">verbergen</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">Top</div> </a> </li> <li id="toc-Beschrijving" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Beschrijving"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Beschrijving</span> </div> </a> <ul id="toc-Beschrijving-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Stolling" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Stolling"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Stolling</span> </div> </a> <ul id="toc-Stolling-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Afweer" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Afweer"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Afweer</span> </div> </a> <ul id="toc-Afweer-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Bepaling" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Bepaling"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Bepaling</span> </div> </a> <ul id="toc-Bepaling-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Ziekten" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Ziekten"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Ziekten</span> </div> </a> <ul id="toc-Ziekten-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Trombocytentransfusie" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Trombocytentransfusie"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>Trombocytentransfusie</span> </div> </a> <ul id="toc-Trombocytentransfusie-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Bloedplaatjes_in_kankerdiagnose" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Bloedplaatjes_in_kankerdiagnose"> <div class="vector-toc-text"> <span class="vector-toc-numb">7</span> <span>Bloedplaatjes in kankerdiagnose</span> </div> </a> <ul id="toc-Bloedplaatjes_in_kankerdiagnose-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Overzicht_hematopoëtische_stamcel_rode_beenmerg" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Overzicht_hematopoëtische_stamcel_rode_beenmerg"> <div class="vector-toc-text"> <span class="vector-toc-numb">8</span> <span>Overzicht hematopoëtische stamcel rode beenmerg</span> </div> </a> <ul id="toc-Overzicht_hematopoëtische_stamcel_rode_beenmerg-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Zie_ook" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Zie_ook"> <div class="vector-toc-text"> <span class="vector-toc-numb">9</span> <span>Zie ook</span> </div> </a> <ul id="toc-Zie_ook-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Inhoud" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Inhoudsopgave omschakelen" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Inhoudsopgave omschakelen</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Bloedplaatje</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Ga naar een artikel in een andere taal. Beschikbaar in 82 talen" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-82" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">82 talen</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-af mw-list-item"><a href="https://af.wikipedia.org/wiki/Bloedplaatjie" title="Bloedplaatjie – Afrikaans" lang="af" hreflang="af" data-title="Bloedplaatjie" data-language-autonym="Afrikaans" data-language-local-name="Afrikaans" class="interlanguage-link-target"><span>Afrikaans</span></a></li><li class="interlanguage-link interwiki-an mw-list-item"><a href="https://an.wikipedia.org/wiki/Plaqueta" title="Plaqueta – Aragonees" lang="an" hreflang="an" data-title="Plaqueta" data-language-autonym="Aragonés" data-language-local-name="Aragonees" class="interlanguage-link-target"><span>Aragonés</span></a></li><li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%B5%D9%81%D9%8A%D8%AD%D8%A9_%D8%AF%D9%85%D9%88%D9%8A%D8%A9" title="صفيحة دموية – Arabisch" lang="ar" hreflang="ar" data-title="صفيحة دموية" data-language-autonym="العربية" data-language-local-name="Arabisch" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-az mw-list-item"><a href="https://az.wikipedia.org/wiki/Trombositl%C9%99r" title="Trombositlər – Azerbeidzjaans" lang="az" hreflang="az" data-title="Trombositlər" data-language-autonym="Azərbaycanca" data-language-local-name="Azerbeidzjaans" class="interlanguage-link-target"><span>Azərbaycanca</span></a></li><li class="interlanguage-link interwiki-be mw-list-item"><a href="https://be.wikipedia.org/wiki/%D0%A2%D1%80%D0%B0%D0%BC%D0%B1%D0%B0%D1%86%D1%8B%D1%82%D1%8B" title="Трамбацыты – Belarussisch" lang="be" hreflang="be" data-title="Трамбацыты" data-language-autonym="Беларуская" data-language-local-name="Belarussisch" class="interlanguage-link-target"><span>Беларуская</span></a></li><li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/%D0%A2%D1%80%D0%BE%D0%BC%D0%B1%D0%BE%D1%86%D0%B8%D1%82" title="Тромбоцит – Bulgaars" lang="bg" hreflang="bg" data-title="Тромбоцит" data-language-autonym="Български" data-language-local-name="Bulgaars" class="interlanguage-link-target"><span>Български</span></a></li><li class="interlanguage-link interwiki-bh mw-list-item"><a href="https://bh.wikipedia.org/wiki/%E0%A4%AA%E0%A5%8D%E0%A4%B2%E0%A5%87%E0%A4%9F%E0%A4%B2%E0%A5%87%E0%A4%9F" title="प्लेटलेट – Bhojpuri" lang="bh" hreflang="bh" data-title="प्लेटलेट" data-language-autonym="भोजपुरी" data-language-local-name="Bhojpuri" class="interlanguage-link-target"><span>भोजपुरी</span></a></li><li class="interlanguage-link interwiki-bn mw-list-item"><a href="https://bn.wikipedia.org/wiki/%E0%A6%85%E0%A6%A3%E0%A7%81%E0%A6%9A%E0%A6%95%E0%A7%8D%E0%A6%B0%E0%A6%BF%E0%A6%95%E0%A6%BE" title="অণুচক্রিকা – Bengaals" lang="bn" hreflang="bn" data-title="অণুচক্রিকা" data-language-autonym="বাংলা" data-language-local-name="Bengaals" class="interlanguage-link-target"><span>বাংলা</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Trombociti" title="Trombociti – Bosnisch" lang="bs" hreflang="bs" data-title="Trombociti" data-language-autonym="Bosanski" data-language-local-name="Bosnisch" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Plaqueta" title="Plaqueta – Catalaans" lang="ca" hreflang="ca" data-title="Plaqueta" data-language-autonym="Català" data-language-local-name="Catalaans" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-ckb mw-list-item"><a href="https://ckb.wikipedia.org/wiki/%D9%BE%DB%95%DA%95%DB%95%DB%8C_%D8%AE%D9%88%DB%8E%D9%86" title="پەڕەی خوێن – Soranî" lang="ckb" hreflang="ckb" data-title="پەڕەی خوێن" data-language-autonym="کوردی" data-language-local-name="Soranî" class="interlanguage-link-target"><span>کوردی</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Krevn%C3%AD_desti%C4%8Dka" title="Krevní destička – Tsjechisch" lang="cs" hreflang="cs" data-title="Krevní destička" data-language-autonym="Čeština" data-language-local-name="Tsjechisch" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-cy mw-list-item"><a href="https://cy.wikipedia.org/wiki/Platennau" title="Platennau – Welsh" lang="cy" hreflang="cy" data-title="Platennau" data-language-autonym="Cymraeg" data-language-local-name="Welsh" class="interlanguage-link-target"><span>Cymraeg</span></a></li><li class="interlanguage-link interwiki-da mw-list-item"><a href="https://da.wikipedia.org/wiki/Blodplade" title="Blodplade – Deens" lang="da" hreflang="da" data-title="Blodplade" data-language-autonym="Dansk" data-language-local-name="Deens" class="interlanguage-link-target"><span>Dansk</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Thrombozyt" title="Thrombozyt – Duits" lang="de" hreflang="de" data-title="Thrombozyt" data-language-autonym="Deutsch" data-language-local-name="Duits" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-dv mw-list-item"><a href="https://dv.wikipedia.org/wiki/%DE%95%DE%B0%DE%8D%DE%AD%DE%93%DE%B0%DE%8D%DE%A8%DE%93%DE%B0" title="ޕްލޭޓްލިޓް – Divehi" lang="dv" hreflang="dv" data-title="ޕްލޭޓްލިޓް" data-language-autonym="ދިވެހިބަސް" data-language-local-name="Divehi" class="interlanguage-link-target"><span>ދިވެހިބަސް</span></a></li><li class="interlanguage-link interwiki-el mw-list-item"><a href="https://el.wikipedia.org/wiki/%CE%91%CE%B9%CE%BC%CE%BF%CF%80%CE%B5%CF%84%CE%AC%CE%BB%CE%B9%CE%BF" title="Αιμοπετάλιο – Grieks" lang="el" hreflang="el" data-title="Αιμοπετάλιο" data-language-autonym="Ελληνικά" data-language-local-name="Grieks" class="interlanguage-link-target"><span>Ελληνικά</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Platelet" title="Platelet – Engels" lang="en" hreflang="en" data-title="Platelet" data-language-autonym="English" data-language-local-name="Engels" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-eo mw-list-item"><a href="https://eo.wikipedia.org/wiki/Trombocito" title="Trombocito – Esperanto" lang="eo" hreflang="eo" data-title="Trombocito" data-language-autonym="Esperanto" data-language-local-name="Esperanto" class="interlanguage-link-target"><span>Esperanto</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Plaqueta" title="Plaqueta – Spaans" lang="es" hreflang="es" data-title="Plaqueta" data-language-autonym="Español" data-language-local-name="Spaans" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-et mw-list-item"><a href="https://et.wikipedia.org/wiki/Vereliistak" title="Vereliistak – Estisch" lang="et" hreflang="et" data-title="Vereliistak" data-language-autonym="Eesti" data-language-local-name="Estisch" class="interlanguage-link-target"><span>Eesti</span></a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/Plaketa" title="Plaketa – Baskisch" lang="eu" hreflang="eu" data-title="Plaketa" data-language-autonym="Euskara" data-language-local-name="Baskisch" class="interlanguage-link-target"><span>Euskara</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D9%BE%D9%84%D8%A7%DA%A9%D8%AA" title="پلاکت – Perzisch" lang="fa" hreflang="fa" data-title="پلاکت" data-language-autonym="فارسی" data-language-local-name="Perzisch" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Verihiutale" title="Verihiutale – Fins" lang="fi" hreflang="fi" data-title="Verihiutale" data-language-autonym="Suomi" data-language-local-name="Fins" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Thrombocyte" title="Thrombocyte – Frans" lang="fr" hreflang="fr" data-title="Thrombocyte" data-language-autonym="Français" data-language-local-name="Frans" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-fy mw-list-item"><a href="https://fy.wikipedia.org/wiki/Bloedplaatsjes" title="Bloedplaatsjes – Fries" lang="fy" hreflang="fy" data-title="Bloedplaatsjes" data-language-autonym="Frysk" data-language-local-name="Fries" class="interlanguage-link-target"><span>Frysk</span></a></li><li class="interlanguage-link interwiki-ga mw-list-item"><a href="https://ga.wikipedia.org/wiki/Pl%C3%A1it%C3%ADn" title="Pláitín – Iers" lang="ga" hreflang="ga" data-title="Pláitín" data-language-autonym="Gaeilge" data-language-local-name="Iers" class="interlanguage-link-target"><span>Gaeilge</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Plaqueta" title="Plaqueta – Galicisch" lang="gl" hreflang="gl" data-title="Plaqueta" data-language-autonym="Galego" data-language-local-name="Galicisch" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%98%D7%A1%D7%99%D7%AA_%D7%93%D7%9D" title="טסית דם – Hebreeuws" lang="he" hreflang="he" data-title="טסית דם" data-language-autonym="עברית" data-language-local-name="Hebreeuws" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-hi mw-list-item"><a href="https://hi.wikipedia.org/wiki/%E0%A4%AC%E0%A4%BF%E0%A4%AE%E0%A5%8D%E0%A4%AC%E0%A4%BE%E0%A4%A3%E0%A5%81" title="बिम्बाणु – Hindi" lang="hi" hreflang="hi" data-title="बिम्बाणु" data-language-autonym="हिन्दी" data-language-local-name="Hindi" class="interlanguage-link-target"><span>हिन्दी</span></a></li><li class="interlanguage-link interwiki-hr mw-list-item"><a href="https://hr.wikipedia.org/wiki/Trombociti" title="Trombociti – Kroatisch" lang="hr" hreflang="hr" data-title="Trombociti" data-language-autonym="Hrvatski" data-language-local-name="Kroatisch" class="interlanguage-link-target"><span>Hrvatski</span></a></li><li class="interlanguage-link interwiki-ht mw-list-item"><a href="https://ht.wikipedia.org/wiki/Plak%C3%A8t" title="Plakèt – Haïtiaans Creools" lang="ht" hreflang="ht" data-title="Plakèt" data-language-autonym="Kreyòl ayisyen" data-language-local-name="Haïtiaans Creools" class="interlanguage-link-target"><span>Kreyòl ayisyen</span></a></li><li class="interlanguage-link interwiki-hy mw-list-item"><a href="https://hy.wikipedia.org/wiki/%D4%B9%D6%80%D5%B8%D5%B4%D5%A2%D5%B8%D6%81%D5%AB%D5%BF" title="Թրոմբոցիտ – Armeens" lang="hy" hreflang="hy" data-title="Թրոմբոցիտ" data-language-autonym="Հայերեն" data-language-local-name="Armeens" class="interlanguage-link-target"><span>Հայերեն</span></a></li><li class="interlanguage-link interwiki-ia mw-list-item"><a href="https://ia.wikipedia.org/wiki/Plachetta" title="Plachetta – Interlingua" lang="ia" hreflang="ia" data-title="Plachetta" data-language-autonym="Interlingua" data-language-local-name="Interlingua" class="interlanguage-link-target"><span>Interlingua</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Keping_darah" title="Keping darah – Indonesisch" lang="id" hreflang="id" data-title="Keping darah" data-language-autonym="Bahasa Indonesia" data-language-local-name="Indonesisch" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-is mw-list-item"><a href="https://is.wikipedia.org/wiki/Bl%C3%B3%C3%B0fl%C3%B6gur" title="Blóðflögur – IJslands" lang="is" hreflang="is" data-title="Blóðflögur" data-language-autonym="Íslenska" data-language-local-name="IJslands" class="interlanguage-link-target"><span>Íslenska</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Piastrina" title="Piastrina – Italiaans" lang="it" hreflang="it" data-title="Piastrina" data-language-autonym="Italiano" data-language-local-name="Italiaans" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja badge-Q17437798 badge-goodarticle mw-list-item" title="goed artikel"><a href="https://ja.wikipedia.org/wiki/%E8%A1%80%E5%B0%8F%E6%9D%BF" title="血小板 – Japans" lang="ja" hreflang="ja" data-title="血小板" data-language-autonym="日本語" data-language-local-name="Japans" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-jv mw-list-item"><a href="https://jv.wikipedia.org/wiki/Trombosit" title="Trombosit – Javaans" lang="jv" hreflang="jv" data-title="Trombosit" data-language-autonym="Jawa" data-language-local-name="Javaans" class="interlanguage-link-target"><span>Jawa</span></a></li><li class="interlanguage-link interwiki-ka mw-list-item"><a href="https://ka.wikipedia.org/wiki/%E1%83%97%E1%83%A0%E1%83%9D%E1%83%9B%E1%83%91%E1%83%9D%E1%83%AA%E1%83%98%E1%83%A2%E1%83%94%E1%83%91%E1%83%98" title="თრომბოციტები – Georgisch" lang="ka" hreflang="ka" data-title="თრომბოციტები" data-language-autonym="ქართული" data-language-local-name="Georgisch" class="interlanguage-link-target"><span>ქართული</span></a></li><li class="interlanguage-link interwiki-kk mw-list-item"><a href="https://kk.wikipedia.org/wiki/%D0%A2%D1%80%D0%BE%D0%BC%D0%B1%D0%BE%D1%86%D0%B8%D1%82" title="Тромбоцит – Kazachs" lang="kk" hreflang="kk" data-title="Тромбоцит" data-language-autonym="Қазақша" data-language-local-name="Kazachs" class="interlanguage-link-target"><span>Қазақша</span></a></li><li class="interlanguage-link interwiki-kn mw-list-item"><a href="https://kn.wikipedia.org/wiki/%E0%B2%95%E0%B2%BF%E0%B2%B0%E0%B3%81%E0%B2%AC%E0%B2%BF%E0%B2%B2%E0%B3%8D%E0%B2%B2%E0%B3%86" title="ಕಿರುಬಿಲ್ಲೆ – Kannada" lang="kn" hreflang="kn" data-title="ಕಿರುಬಿಲ್ಲೆ" data-language-autonym="ಕನ್ನಡ" data-language-local-name="Kannada" class="interlanguage-link-target"><span>ಕನ್ನಡ</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%ED%98%88%EC%86%8C%ED%8C%90" title="혈소판 – Koreaans" lang="ko" hreflang="ko" data-title="혈소판" data-language-autonym="한국어" data-language-local-name="Koreaans" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-ku mw-list-item"><a href="https://ku.wikipedia.org/wiki/Perik%C3%AAn_xw%C3%AEn%C3%AA" title="Perikên xwînê – Koerdisch" lang="ku" hreflang="ku" data-title="Perikên xwînê" data-language-autonym="Kurdî" data-language-local-name="Koerdisch" class="interlanguage-link-target"><span>Kurdî</span></a></li><li class="interlanguage-link interwiki-ky mw-list-item"><a href="https://ky.wikipedia.org/wiki/%D0%A2%D1%80%D0%BE%D0%BC%D0%B1%D0%BE%D1%86%D0%B8%D1%82%D1%82%D0%B5%D1%80" title="Тромбоциттер – Kirgizisch" lang="ky" hreflang="ky" data-title="Тромбоциттер" data-language-autonym="Кыргызча" data-language-local-name="Kirgizisch" class="interlanguage-link-target"><span>Кыргызча</span></a></li><li class="interlanguage-link interwiki-la mw-list-item"><a href="https://la.wikipedia.org/wiki/Thrombocytus" title="Thrombocytus – Latijn" lang="la" hreflang="la" data-title="Thrombocytus" data-language-autonym="Latina" data-language-local-name="Latijn" class="interlanguage-link-target"><span>Latina</span></a></li><li class="interlanguage-link interwiki-lmo mw-list-item"><a href="https://lmo.wikipedia.org/wiki/Trombocitt" title="Trombocitt – Lombardisch" lang="lmo" hreflang="lmo" data-title="Trombocitt" data-language-autonym="Lombard" data-language-local-name="Lombardisch" class="interlanguage-link-target"><span>Lombard</span></a></li><li class="interlanguage-link interwiki-lt mw-list-item"><a href="https://lt.wikipedia.org/wiki/Trombocitas" title="Trombocitas – Litouws" lang="lt" hreflang="lt" data-title="Trombocitas" data-language-autonym="Lietuvių" data-language-local-name="Litouws" class="interlanguage-link-target"><span>Lietuvių</span></a></li><li class="interlanguage-link interwiki-lv mw-list-item"><a href="https://lv.wikipedia.org/wiki/Tromboc%C4%ABti" title="Trombocīti – Lets" lang="lv" hreflang="lv" data-title="Trombocīti" data-language-autonym="Latviešu" data-language-local-name="Lets" class="interlanguage-link-target"><span>Latviešu</span></a></li><li class="interlanguage-link interwiki-mk mw-list-item"><a href="https://mk.wikipedia.org/wiki/%D0%9A%D1%80%D0%B2%D0%BD%D0%B8_%D0%BF%D0%BB%D0%BE%D1%87%D0%BA%D0%B8" title="Крвни плочки – Macedonisch" lang="mk" hreflang="mk" data-title="Крвни плочки" data-language-autonym="Македонски" data-language-local-name="Macedonisch" class="interlanguage-link-target"><span>Македонски</span></a></li><li class="interlanguage-link interwiki-ml mw-list-item"><a href="https://ml.wikipedia.org/wiki/%E0%B4%AA%E0%B5%8D%E0%B4%B2%E0%B5%87%E0%B4%B1%E0%B5%8D%E0%B4%B1%E0%B5%8D%E2%80%8C%E0%B4%B2%E0%B5%86%E0%B4%B1%E0%B5%8D%E0%B4%B1%E0%B5%8D" title="പ്ലേറ്റ്‌ലെറ്റ് – Malayalam" lang="ml" hreflang="ml" data-title="പ്ലേറ്റ്‌ലെറ്റ്" data-language-autonym="മലയാളം" data-language-local-name="Malayalam" class="interlanguage-link-target"><span>മലയാളം</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Platelet" title="Platelet – Maleis" lang="ms" hreflang="ms" data-title="Platelet" data-language-autonym="Bahasa Melayu" data-language-local-name="Maleis" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-nds mw-list-item"><a href="https://nds.wikipedia.org/wiki/Bloodplattken" title="Bloodplattken – Nedersaksisch" lang="nds" hreflang="nds" data-title="Bloodplattken" data-language-autonym="Plattdüütsch" data-language-local-name="Nedersaksisch" class="interlanguage-link-target"><span>Plattdüütsch</span></a></li><li class="interlanguage-link interwiki-no mw-list-item"><a href="https://no.wikipedia.org/wiki/Blodplate" title="Blodplate – Noors - Bokmål" lang="nb" hreflang="nb" data-title="Blodplate" data-language-autonym="Norsk bokmål" data-language-local-name="Noors - Bokmål" class="interlanguage-link-target"><span>Norsk bokmål</span></a></li><li class="interlanguage-link interwiki-oc mw-list-item"><a href="https://oc.wikipedia.org/wiki/Plaqueta" title="Plaqueta – Occitaans" lang="oc" hreflang="oc" data-title="Plaqueta" data-language-autonym="Occitan" data-language-local-name="Occitaans" class="interlanguage-link-target"><span>Occitan</span></a></li><li class="interlanguage-link interwiki-om mw-list-item"><a href="https://om.wikipedia.org/wiki/Pilaatileetii" title="Pilaatileetii – Afaan Oromo" lang="om" hreflang="om" data-title="Pilaatileetii" data-language-autonym="Oromoo" data-language-local-name="Afaan Oromo" class="interlanguage-link-target"><span>Oromoo</span></a></li><li class="interlanguage-link interwiki-pa mw-list-item"><a href="https://pa.wikipedia.org/wiki/%E0%A8%AA%E0%A8%B2%E0%A9%87%E0%A8%9F%E0%A8%B2%E0%A9%88%E0%A9%B1%E0%A8%9F" title="ਪਲੇਟਲੈੱਟ – Punjabi" lang="pa" hreflang="pa" data-title="ਪਲੇਟਲੈੱਟ" data-language-autonym="ਪੰਜਾਬੀ" data-language-local-name="Punjabi" class="interlanguage-link-target"><span>ਪੰਜਾਬੀ</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Trombocyt" title="Trombocyt – Pools" lang="pl" hreflang="pl" data-title="Trombocyt" data-language-autonym="Polski" data-language-local-name="Pools" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pnb mw-list-item"><a href="https://pnb.wikipedia.org/wiki/%D9%BE%D9%84%DB%8C%D9%B9%D9%84%DB%8C%D9%B9" title="پلیٹلیٹ – Western Punjabi" lang="pnb" hreflang="pnb" data-title="پلیٹلیٹ" data-language-autonym="پنجابی" data-language-local-name="Western Punjabi" class="interlanguage-link-target"><span>پنجابی</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Plaqueta" title="Plaqueta – Portugees" lang="pt" hreflang="pt" data-title="Plaqueta" data-language-autonym="Português" data-language-local-name="Portugees" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-qu mw-list-item"><a href="https://qu.wikipedia.org/wiki/Yawar_llukllunacha" title="Yawar llukllunacha – Quechua" lang="qu" hreflang="qu" data-title="Yawar llukllunacha" data-language-autonym="Runa Simi" data-language-local-name="Quechua" class="interlanguage-link-target"><span>Runa Simi</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Trombocit" title="Trombocit – Roemeens" lang="ro" hreflang="ro" data-title="Trombocit" data-language-autonym="Română" data-language-local-name="Roemeens" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%A2%D1%80%D0%BE%D0%BC%D0%B1%D0%BE%D1%86%D0%B8%D1%82%D1%8B" title="Тромбоциты – Russisch" lang="ru" hreflang="ru" data-title="Тромбоциты" data-language-autonym="Русский" data-language-local-name="Russisch" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Trombociti" title="Trombociti – Servo-Kroatisch" lang="sh" hreflang="sh" data-title="Trombociti" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="Servo-Kroatisch" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-simple mw-list-item"><a href="https://simple.wikipedia.org/wiki/Platelet" title="Platelet – Simple English" lang="en-simple" hreflang="en-simple" data-title="Platelet" data-language-autonym="Simple English" data-language-local-name="Simple English" class="interlanguage-link-target"><span>Simple English</span></a></li><li class="interlanguage-link interwiki-sk mw-list-item"><a href="https://sk.wikipedia.org/wiki/Krvn%C3%A1_do%C5%A1ti%C4%8Dka" title="Krvná doštička – Slowaaks" lang="sk" hreflang="sk" data-title="Krvná doštička" data-language-autonym="Slovenčina" data-language-local-name="Slowaaks" class="interlanguage-link-target"><span>Slovenčina</span></a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Trombocit" title="Trombocit – Sloveens" lang="sl" hreflang="sl" data-title="Trombocit" data-language-autonym="Slovenščina" data-language-local-name="Sloveens" class="interlanguage-link-target"><span>Slovenščina</span></a></li><li class="interlanguage-link interwiki-sq mw-list-item"><a href="https://sq.wikipedia.org/wiki/Trombociti" title="Trombociti – Albanees" lang="sq" hreflang="sq" data-title="Trombociti" data-language-autonym="Shqip" data-language-local-name="Albanees" class="interlanguage-link-target"><span>Shqip</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/%D0%9A%D1%80%D0%B2%D0%BD%D0%B5_%D0%BF%D0%BB%D0%BE%D1%87%D0%B8%D1%86%D0%B5" title="Крвне плочице – Servisch" lang="sr" hreflang="sr" data-title="Крвне плочице" data-language-autonym="Српски / srpski" data-language-local-name="Servisch" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-su mw-list-item"><a href="https://su.wikipedia.org/wiki/Trombosit" title="Trombosit – Soendanees" lang="su" hreflang="su" data-title="Trombosit" data-language-autonym="Sunda" data-language-local-name="Soendanees" class="interlanguage-link-target"><span>Sunda</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Trombocyt" title="Trombocyt – Zweeds" lang="sv" hreflang="sv" data-title="Trombocyt" data-language-autonym="Svenska" data-language-local-name="Zweeds" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-sw mw-list-item"><a href="https://sw.wikipedia.org/wiki/Pleteleti_za_damu" title="Pleteleti za damu – Swahili" lang="sw" hreflang="sw" data-title="Pleteleti za damu" data-language-autonym="Kiswahili" data-language-local-name="Swahili" class="interlanguage-link-target"><span>Kiswahili</span></a></li><li class="interlanguage-link interwiki-ta mw-list-item"><a href="https://ta.wikipedia.org/wiki/%E0%AE%95%E0%AF%81%E0%AE%B0%E0%AF%81%E0%AE%A4%E0%AE%BF%E0%AE%9A%E0%AF%8D_%E0%AE%9A%E0%AE%BF%E0%AE%B1%E0%AF%81%E0%AE%A4%E0%AE%9F%E0%AF%8D%E0%AE%9F%E0%AF%81%E0%AE%95%E0%AF%8D%E0%AE%95%E0%AE%B3%E0%AF%8D" title="குருதிச் சிறுதட்டுக்கள் – Tamil" lang="ta" hreflang="ta" data-title="குருதிச் சிறுதட்டுக்கள்" data-language-autonym="தமிழ்" data-language-local-name="Tamil" class="interlanguage-link-target"><span>தமிழ்</span></a></li><li class="interlanguage-link interwiki-th mw-list-item"><a href="https://th.wikipedia.org/wiki/%E0%B9%80%E0%B8%81%E0%B8%A5%E0%B9%87%E0%B8%94%E0%B9%80%E0%B8%A5%E0%B8%B7%E0%B8%AD%E0%B8%94" title="เกล็ดเลือด – Thai" lang="th" hreflang="th" data-title="เกล็ดเลือด" data-language-autonym="ไทย" data-language-local-name="Thai" class="interlanguage-link-target"><span>ไทย</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Trombosit" title="Trombosit – Turks" lang="tr" hreflang="tr" data-title="Trombosit" data-language-autonym="Türkçe" data-language-local-name="Turks" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%A2%D1%80%D0%BE%D0%BC%D0%B1%D0%BE%D1%86%D0%B8%D1%82%D0%B8" title="Тромбоцити – Oekraïens" lang="uk" hreflang="uk" data-title="Тромбоцити" data-language-autonym="Українська" data-language-local-name="Oekraïens" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-ur mw-list-item"><a href="https://ur.wikipedia.org/wiki/%D8%A7%D9%82%D8%B1%D8%A7%D8%B5_%D8%AE%D9%88%D9%86" title="اقراص خون – Urdu" lang="ur" hreflang="ur" data-title="اقراص خون" data-language-autonym="اردو" data-language-local-name="Urdu" class="interlanguage-link-target"><span>اردو</span></a></li><li class="interlanguage-link interwiki-uz mw-list-item"><a href="https://uz.wikipedia.org/wiki/Trombotsitlar" title="Trombotsitlar – Oezbeeks" lang="uz" hreflang="uz" data-title="Trombotsitlar" data-language-autonym="Oʻzbekcha / ўзбекча" data-language-local-name="Oezbeeks" class="interlanguage-link-target"><span>Oʻzbekcha / ўзбекча</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Ti%E1%BB%83u_c%E1%BA%A7u" title="Tiểu cầu – Vietnamees" lang="vi" hreflang="vi" data-title="Tiểu cầu" data-language-autonym="Tiếng Việt" data-language-local-name="Vietnamees" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-wuu mw-list-item"><a href="https://wuu.wikipedia.org/wiki/%E8%A1%80%E5%B0%8F%E6%9D%BF" title="血小板 – Wuyu" lang="wuu" hreflang="wuu" data-title="血小板" data-language-autonym="吴语" data-language-local-name="Wuyu" class="interlanguage-link-target"><span>吴语</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E8%A1%80%E5%B0%8F%E6%9D%BF" title="血小板 – Chinees" lang="zh" hreflang="zh" data-title="血小板" data-language-autonym="中文" data-language-local-name="Chinees" class="interlanguage-link-target"><span>中文</span></a></li><li class="interlanguage-link interwiki-zh-yue mw-list-item"><a href="https://zh-yue.wikipedia.org/wiki/%E8%A1%80%E5%B0%8F%E6%9D%BF" title="血小板 – Kantonees" lang="yue" 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id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="nl" dir="ltr"><figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/Bestand:Red_White_Blood_cells.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/2/24/Red_White_Blood_cells.jpg/260px-Red_White_Blood_cells.jpg" decoding="async" width="260" height="170" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/24/Red_White_Blood_cells.jpg/390px-Red_White_Blood_cells.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/2/24/Red_White_Blood_cells.jpg 2x" data-file-width="500" data-file-height="326" /></a><figcaption>Rode en witte bloedcel en in het midden een bloedplaatje</figcaption></figure> <p><b>Bloedplaatjes</b> of <b>trombocyten</b> zijn de kleinste <a href="/wiki/Cel_(biologie)" title="Cel (biologie)">cellen</a> (2-3 <a href="/wiki/Micrometer_(eenheid)" title="Micrometer (eenheid)">µm</a> groot) in het <a href="/wiki/Bloed" title="Bloed">bloed</a>. Zij hebben geen <a href="/wiki/Celkern" title="Celkern">celkern</a>. Bloedplaatjes zijn belangrijk voor de <a href="/wiki/Bloedstolling" title="Bloedstolling">bloedstolling</a> na <a href="/wiki/Verwonding" title="Verwonding">verwonding</a> (<a href="/wiki/Hemostase" title="Hemostase">hemostase</a>). </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Beschrijving">Beschrijving</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Bloedplaatje&veaction=edit&section=1" title="Bewerk dit kopje: Beschrijving" class="mw-editsection-visualeditor"><span>bewerken</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Bloedplaatje&action=edit&section=1" title="De broncode bewerken van de sectie: Beschrijving"><span>brontekst bewerken</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Bloedplaatjes worden net als de andere <a href="/wiki/Bloedcel" title="Bloedcel">bloedcellen</a> <a href="/wiki/Trombopo%C3%ABse" title="Trombopoëse">gevormd</a> in het <a href="/wiki/Beenmerg" title="Beenmerg">beenmerg</a>. Trombopoëtine, een hormoon, stimuleert de ontwikkeling en proliferatie van reuscellen die <a href="/wiki/Megakaryoblast" title="Megakaryoblast">megakaryoblasten</a> worden genoemd. Deze reuscellen ondergaan <a href="/wiki/Endomitose" title="Endomitose">endomitose</a>. Dat wil zeggen dat de kern van de cel zich deelt, terwijl de cel hierbij niet groter wordt. De megakaryoblasten differentiëren zich tot <a href="/wiki/Megakaryocyt" title="Megakaryocyt">megakaryocyten</a>. Deze cellen hebben een goed ontwikkeld <a href="/wiki/Golgiapparaat" class="mw-redirect" title="Golgiapparaat">golgiapparaat</a>, vele <a href="/wiki/Mitochondrion" title="Mitochondrion">mitochondriën</a>, ruw <a href="/wiki/Endoplasmatisch_reticulum" title="Endoplasmatisch reticulum">endoplasmatisch reticulum</a> en <a href="/wiki/Lysosoom" title="Lysosoom">lysosomen</a>. Door afsnoeringen van de megakaryocyt worden bloedplaatjes gevormd. Uit een megakaryocyt kunnen wel duizenden bloedplaatjes worden gevormd. Bloedplaatjes zijn dus eigenlijk geen volledige <a href="/wiki/Cel_(biologie)" title="Cel (biologie)">cellen</a> meer maar slechts fragmentjes. De levensduur van een bloedplaatje in de bloedsomloop is ongeveer 8 à 10 dagen. De afbraak van bloedplaatjes vindt plaats in de <a href="/wiki/Milt" title="Milt">milt</a> en de <a href="/wiki/Lever" title="Lever">lever</a>. </p> <div class="mw-heading mw-heading2"><h2 id="Stolling">Stolling</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Bloedplaatje&veaction=edit&section=2" title="Bewerk dit kopje: Stolling" class="mw-editsection-visualeditor"><span>bewerken</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Bloedplaatje&action=edit&section=2" title="De broncode bewerken van de sectie: Stolling"><span>brontekst bewerken</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Als een bloedvatwand beschadigd is, gaan de bloedplaatjes aan de beschadigde wand plakken. Dit komt door binding van de bloedplaatjes aan <a href="/wiki/Collageen" title="Collageen">collageenvezels</a> die door de beschadiging bloot zijn komen te liggen. Daarnaast plakken de bloedplaatjes ook aan elkaar, aggregeren, en begint er zich een prop te vormen. Ook wordt <a href="/wiki/Fibrine" title="Fibrine">fibrine</a> gevormd uit <a href="/wiki/Fibrinogeen" title="Fibrinogeen">fibrinogeen</a>. Fibrine is een vezelachtige stof dat een netwerk van draden gaat vormen om de bloedprop te verstevigen. Daarbij komt ook <a href="/wiki/Tromboplastine" title="Tromboplastine">tromboplastine</a> vrij uit het beschadigde weefsel. Het vrijgekomen tromboplastine en het plakken van de bloedplaatjes staan aan het begin van een ingewikkelde keten van reacties, <a href="/wiki/Bloedstolling" title="Bloedstolling">bloedstolling</a>, die eindigt met het ontstaan van een bloedstolsel. Zo kan er een afsluitende <a href="/wiki/Embolie" title="Embolie">bloedprop</a> gevormd worden. </p> <div class="mw-heading mw-heading2"><h2 id="Afweer">Afweer</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Bloedplaatje&veaction=edit&section=3" title="Bewerk dit kopje: Afweer" class="mw-editsection-visualeditor"><span>bewerken</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Bloedplaatje&action=edit&section=3" title="De broncode bewerken van de sectie: Afweer"><span>brontekst bewerken</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Bij een <a href="/wiki/Virusinfectie" class="mw-redirect" title="Virusinfectie">virusinfectie</a> nemen bloedplaatjes <a href="/wiki/Virus_(biologie)" title="Virus (biologie)">virusdeeltjes</a> op uit de longen, waarna ze terugkeren in de <a href="/wiki/Bloedbaan" class="mw-redirect" title="Bloedbaan">bloedbaan</a> en vervolgens worden opgeruimd in lever of milt. Dit mechanisme kan leiden tot een tekort aan bloedplaatjes met als gevolg een risico op stollings- en acute hart- en vaatproblemen.<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Bepaling">Bepaling</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Bloedplaatje&veaction=edit&section=4" title="Bewerk dit kopje: Bepaling" class="mw-editsection-visualeditor"><span>bewerken</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Bloedplaatje&action=edit&section=4" title="De broncode bewerken van de sectie: Bepaling"><span>brontekst bewerken</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Om te onderzoeken of iemand te weinig, genoeg of te veel bloedplaatjes in zijn bloed heeft, wordt in een <a href="/wiki/Klinische_chemie" title="Klinische chemie">klinisch chemisch laboratorium</a> in het ziekenhuis of in een huisartsenlaboratorium het aantal bloedplaatjes bepaald. Dit gebeurt meestal met een zogenaamd hemocytometrie-apparaat. Dit apparaat kan met behulp van een impedantie of een optische meting bepalen wat de concentratie bloedplaatjes in iemands bloed is. Soms echter gaan de bloedplaatjes klonteren in de buis waarin het bloed afgenomen is. Dit heet EDTA-pseudothrombocytopenie. Het is onschuldig voor de patiënt (dit klonteren gebeurt alleen in de buis), maar het aantal bloedplaatjes is dan niet meer nauwkeurig te bepalen. Bij patiënten met dit fenomeen wordt dan bloed in een buisje met <a href="/wiki/Citroenzuur" title="Citroenzuur">citraat</a> afgenomen om zo het aantal trombocyten (bloedplaatjes) te kunnen bepalen. Over het algemeen heeft het anti-stollingsmiddel in deze buis geen effect op de klontering van de trombocyten na de afname. </p><p>Naast afwijkingen in het aantal bloedplaatjes kan er in het klinisch chemisch laboratorium ook onderzoek gedaan worden naar het vermogen van de bloedplaatjes om te aggregeren, samen te klonteren. Dit onderzoek wordt trombocytenfunctie-onderzoek ofwel <a href="/w/index.php?title=Trombocytenaggregatie&action=edit&redlink=1" class="new" title="Trombocytenaggregatie (de pagina bestaat niet)">trombocytenaggregatie</a>-onderzoek genoemd. Er worden verschillende stoffen aan de bloedplaatjes toegevoegd die bloedplaatjes van gezonde personen laten samenklonteren. Met dit onderzoek kunnen afwijkingen in het functioneren van bloedplaatjes opgespoord worden. </p> <div class="mw-heading mw-heading2"><h2 id="Ziekten">Ziekten</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Bloedplaatje&veaction=edit&section=5" title="Bewerk dit kopje: Ziekten" class="mw-editsection-visualeditor"><span>bewerken</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Bloedplaatje&action=edit&section=5" title="De broncode bewerken van de sectie: Ziekten"><span>brontekst bewerken</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Trombocytopenie" title="Trombocytopenie">Trombocytopenie</a>: een tekort aan bloedplaatjes in het bloed. Het gevolg is dat bloedingen door beschadigingen van de vaatwand niet goed worden gestelpt, wat in ernstige gevallen levensgevaarlijk kan zijn. Ook krijgt men snel blauwe plekken.</li> <li><a href="/wiki/Trombocytose" class="mw-redirect" title="Trombocytose">Trombocytose</a>: een teveel aan bloedplaatjes in het bloed. Hierdoor kunnen spontane bloedstolsels ontstaan (<a href="/wiki/Trombose" title="Trombose">trombose</a>).</li> <li><a href="/w/index.php?title=Trombocytopathie&action=edit&redlink=1" class="new" title="Trombocytopathie (de pagina bestaat niet)">Trombocytopathie</a>: de bloedplaatjes hebben dan een gestoorde functie en doen niet wat ze doen moeten. De symptomen zijn vergelijkbaar met trombocytopenie.</li></ul> <div class="mw-heading mw-heading2"><h2 id="Trombocytentransfusie">Trombocytentransfusie</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Bloedplaatje&veaction=edit&section=6" title="Bewerk dit kopje: Trombocytentransfusie" class="mw-editsection-visualeditor"><span>bewerken</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Bloedplaatje&action=edit&section=6" title="De broncode bewerken van de sectie: Trombocytentransfusie"><span>brontekst bewerken</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Bij een tekort aan trombocyten en risico op bloedingen, kan het soms nodig zijn om een <a href="/wiki/Bloedtransfusie" title="Bloedtransfusie">trombocytentransfusie</a> te geven. Een tekort aan trombocyten wordt dan aangevuld door de patiënt een trombcytenconcentraat verkregen van <a href="/wiki/Donor_(geneeskunde)" title="Donor (geneeskunde)">donoren</a> toe te dienen. Omdat het aanbod van trombocyten gering is, en de levensduur van een getransfundeerde trombocyt maar een paar dagen, heeft dit alleen zin als er uitzicht bestaat dat het trombocytentekort van beperkte duur is. Het wordt b.v. niet gedaan bij mensen die om wat voor reden dan ook geen functionerend beenmerg meer hebben en dat ook niet meer gaan krijgen. </p> <div class="mw-heading mw-heading2"><h2 id="Bloedplaatjes_in_kankerdiagnose">Bloedplaatjes in kankerdiagnose</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Bloedplaatje&veaction=edit&section=7" title="Bewerk dit kopje: Bloedplaatjes in kankerdiagnose" class="mw-editsection-visualeditor"><span>bewerken</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Bloedplaatje&action=edit&section=7" title="De broncode bewerken van de sectie: Bloedplaatjes in kankerdiagnose"><span>brontekst bewerken</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Uit onderzoek is in 2015 gebleken dat bloedplaatjes van patiënten met kanker unieke <a href="/wiki/Ribonucle%C3%AFnezuur" title="Ribonucleïnezuur">RNA</a>-patronen bevatten die het mogelijk maken om gezonde individuen te onderscheiden van kankerpatiënten met een zekerheid van 96%.<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Overzicht_hematopoëtische_stamcel_rode_beenmerg"><span id="Overzicht_hematopo.C3.ABtische_stamcel_rode_beenmerg"></span>Overzicht <a href="/wiki/Hematopo%C3%ABtische_stamcel" title="Hematopoëtische stamcel">hematopoëtische stamcel</a> rode beenmerg</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Bloedplaatje&veaction=edit&section=8" title="Bewerk dit kopje: Overzicht hematopoëtische stamcel rode beenmerg" class="mw-editsection-visualeditor"><span>bewerken</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Bloedplaatje&action=edit&section=8" title="De broncode bewerken van de sectie: Overzicht hematopoëtische stamcel rode beenmerg"><span>brontekst bewerken</span></a><span class="mw-editsection-bracket">]</span></span></div> <table class="wikitable vatop" style="text-align:center"> <tbody><tr> <th colspan="10"><a href="/wiki/Hematopo%C3%ABse" title="Hematopoëse">Hematopoëse</a> </th></tr> <tr> <td colspan="8"><a href="/wiki/Leukopo%C3%ABse" title="Leukopoëse">Leukopoëse</a> </td> <td><a href="/wiki/Erytropo%C3%ABse" title="Erytropoëse">Erytropoëse</a> </td> <td><a href="/wiki/Trombopo%C3%ABse" title="Trombopoëse">Trombopoëse</a> </td></tr> <tr> <td rowspan="3" colspan="3"><br /><a href="/wiki/Myeloblast" title="Myeloblast">Myeloblast</a> </td> <td rowspan="3"><br /><a href="/wiki/Monoblast" title="Monoblast">Monoblast</a> </td> <td rowspan="3" colspan="3"><br /><a href="/wiki/Lymfoblast" title="Lymfoblast">Lymfoblast</a> </td> <td rowspan="4"> </td> <td><a href="/wiki/Pro-erytroblast" title="Pro-erytroblast">Pro-erytroblast</a> </td> <td rowspan="3"><br /><a href="/wiki/Megakaryoblast" title="Megakaryoblast">Megakaryoblast</a> </td></tr> <tr> <td><a href="/wiki/Erytroblast" title="Erytroblast">Erytroblast</a> </td></tr> <tr> <td><a href="/wiki/Normoblast" title="Normoblast">Normoblast</a> </td></tr> <tr> <td colspan="3"><a href="/wiki/Promyelocyt" title="Promyelocyt">Promyelocyt</a> </td> <td><a href="/wiki/Monocyt" title="Monocyt">Monocyt</a> </td> <td colspan="3"><a href="/wiki/Lymfocyt" title="Lymfocyt">Lymfocyt</a> </td> <td><a href="/wiki/Reticulocyt" title="Reticulocyt">Reticulocyt</a> </td> <td><a href="/wiki/Megakaryocyt" title="Megakaryocyt">Megakaryocyt</a> </td></tr> <tr> <td><a href="/wiki/Neutrofiele_granulocyt" title="Neutrofiele granulocyt">Neutrofiele<br />granulocyt</a> </td> <td><a href="/wiki/Basofiele_granulocyt" title="Basofiele granulocyt">Basofiele<br />granulocyt</a> </td> <td><a href="/wiki/Eosinofiele_granulocyt" title="Eosinofiele granulocyt">Eosinofiele<br />granulocyt</a> </td> <td><a href="/wiki/Macrofaag" title="Macrofaag">Macrofaag</a> </td> <td><a href="/wiki/B-cel" title="B-cel">B-cel</a> </td> <td><a href="/wiki/T-cel" title="T-cel">T-cel</a> </td> <td><a href="/wiki/NK-cel" title="NK-cel">NK-cel</a> </td> <td><a href="/wiki/Mestcel" title="Mestcel">Mastocyt</a> </td> <td><a href="/wiki/Rode_bloedcel" title="Rode bloedcel">Erytrocyt</a> </td> <td><a class="mw-selflink selflink">Trombocyt</a> </td></tr></tbody></table> <div class="mw-heading mw-heading2"><h2 id="Zie_ook">Zie ook</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Bloedplaatje&veaction=edit&section=9" title="Bewerk dit kopje: Zie ook" class="mw-editsection-visualeditor"><span>bewerken</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Bloedplaatje&action=edit&section=9" title="De broncode bewerken van de sectie: Zie ook"><span>brontekst bewerken</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Hematopo%C3%ABse" title="Hematopoëse">Hematopoëse</a></li> <li><a href="/wiki/Trombopo%C3%ABse" title="Trombopoëse">Trombopoëse</a></li></ul> <div class="toccolours appendix" role="presentation" style="font-size:90%; margin:1em 0 -0.5em; clear:both;"> <div><span style="font-weight:bold">Bronnen, noten en/of referenties</span></div> <div class="reflist" style="list-style-type: decimal;"><div class="mw-references-wrap"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><a href="#cite_ref-1">↑</a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="https://www.umcutrecht.nl/nieuws/rol-bloedplaatjes-bij-stolling-en-afweer">Umcutrecht.nl, <i>Rol bloedplaatjes bij stolling en afweer</i>, nieuwsbericht van 1 juli 2020</a></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><a href="#cite_ref-2">↑</a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="https://www.vumc.nl/nieuws/nieuwsdetail/druppel-bloed-straks-voldoende-voor-diagnosticeren-kanker.htm">Druppel bloed straks voldoende voor diagnosticeren kanker</a>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20220525141003/https://www.vumc.nl/nieuws/nieuwsdetail/druppel-bloed-straks-voldoende-voor-diagnosticeren-kanker.htm">Gearchiveerd</a> op 25 mei 2022.</span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><a href="#cite_ref-3">↑</a></span> <span class="reference-text"><span class="citation"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20150922015959/http://mediator.zonmw.nl/mediator-5-april-2014/tumor-doorgronden-via-bloedplaatjes/">Tumor doorgronden via bloedplaatjes</a>. Gearchiveerd op <span class="mw-formatted-date" title="2015-09-22">22 september 2015</span>. Geraadpleegd op <span class="mw-formatted-date" title="2015-11-09">9 november 2015</span>. </span></span> </li> </ol></div></div> </div>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">Overgenomen van "<a dir="ltr" href="https://nl.wikipedia.org/w/index.php?title=Bloedplaatje&oldid=68060748">https://nl.wikipedia.org/w/index.php?title=Bloedplaatje&oldid=68060748</a>"</div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/Categorie:Alles" title="Categorie:Alles">Categorieën</a>: <ul><li><a href="/wiki/Categorie:Hematologie" title="Categorie:Hematologie">Hematologie</a></li><li><a href="/wiki/Categorie:Cel" title="Categorie:Cel">Cel</a></li></ul></div></div> </div> </main> </div> <div class="mw-footer-container"> <footer id="footer" class="mw-footer" > <ul id="footer-info"> <li id="footer-info-lastmod"> Deze pagina is voor het laatst bewerkt op 3 sep 2024 om 08:18.</li> <li id="footer-info-copyright">De tekst is beschikbaar onder de licentie <a rel="nofollow" class="external text" href="//creativecommons.org/licenses/by-sa/4.0/deed.nl">Creative Commons Naamsvermelding/Gelijk delen</a>, er kunnen aanvullende voorwaarden van toepassing zijn. 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